• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Wake Hidenori  和氣 秀徳

ORCIDConnect your ORCID iD *help
… Alternative Names

WAKE Hidenori  和氣 秀徳

Less
Researcher Number 60570520
Other IDs
Affiliation (Current) 2025: 近畿大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2023 – 2025: 近畿大学, 医学部, 准教授
2020 – 2022: 近畿大学, 医学部, 講師
2017 – 2019: 岡山大学, 医歯薬学総合研究科, 講師
2016: 岡山大学, 医歯薬学総合研究科, 助教
2014 – 2015: 岡山大学, 大学院医歯薬学総合研究科, 助教
2011 – 2015: 岡山大学, 医歯(薬)学総合研究科, 助教
2011 – 2012: 岡山大学, 大学院・医歯薬学総合研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 55060:Emergency medicine-related / Basic Section 48030:Pharmacology-related / General pharmacology / Applied pharmacology
Except Principal Investigator
General pharmacology / Applied pharmacology / Basic Section 59010:Rehabilitation science-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 56020:Orthopedics-related / Basic Section 47040:Pharmacology-related … More / Basic Section 48030:Pharmacology-related / Basic Section 49010:Pathological biochemistry-related / Periodontology / Biological pharmacy / Cerebral neurosurgery Less
Keywords
Principal Investigator
2価鉄イオン / 血管内皮障害 / 敗血症 / HRG / グリコカリックス / 細胞死 / 血管内皮細胞 / 高ヒスチジン糖タンパク質 / HRG / Immunothrombosis … More / In vivoイメージング / Immunothrombosis / 免疫血栓 / 活性酸素 / 免疫血栓形成 / HMGB1 / 抗腫瘍薬 / 抗体医薬 / 薬物治療学 … More
Except Principal Investigator
HMGB1 / HRG / 炎症 / 血管新生 / 抗体医薬 / 脳浮腫 / 血管内皮細胞 / 炎症性サイトカイン / 高ヒスチジン糖タンパク / 敗血症 / 慢性炎症 / ミクログリア / 脳外傷 / 血液脳関門 / 高ヒスチジン糖蛋白質 / 再生、修復促進 / ホメオスタシス / ヒト由来血管内皮細胞株 / 創傷治癒 / 運動介入 / 食品 / 細胞老化 / Inflammaging / 終末糖化産物 / TNF / 疼痛 / 変形性膝関節症 / 炎症性メディエーター / IL-33 / IL33 / DAMP / ヒスタミン / 血漿糖タンパク質 / 炎症生サイトカイン / 慢性炎症性疾患 / 抗HMGB1抗体 / サイトカイン類 / トランスロケーション / 胎盤形成 / 妊娠高血圧 / 血圧 / 妊娠 / 高血圧 / 高ヒスチジン血漿タンパク / 胎盤 / 血管リモデリング / トロホブラスト / 妊娠高血圧症候群 / 遺伝子 / 免疫学 / 歯学 / 抗体療法 / 歯周炎 / 好中球 / 歯肉上皮細胞 / マクロファージ / サイトカイン / 歯周病 / 生活習慣病 / 遺伝子発現 / 肝 / DAMPs / 血漿タンパク / 急性炎症 / トランスレーションリサーチ / 蛋白質 / ARDS / Immunothrombus / トランスレーショナルリサーチ / 薬理学 / 神経細胞 / アストロサイト / 神経 / AGE / RAGE / アミロイドβ / アルツハイマー / 脳腫瘍 / 脊髄損傷 / グリチルリチン / 血液-脳関門 / 抗体治療 / 脳梗塞 / 脳血管透過性 Less
  • Research Projects

    (18 results)
  • Research Products

    (298 results)
  • Co-Researchers

    (33 People)
  •  新規Anti-PAMPs因子HRGのPAMPs誘発敗血症関連血液血管系細胞応答反応への作用Principal Investigator

    • Principal Investigator
      和氣 秀徳
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Kindai University
  •  Role of TNF-alpha in knee osteoarthritis pain and analgesic effect of plasma protein HRG

    • Principal Investigator
      ハティポール オメル・ファルク
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Kindai University
  •  Development of control method for inflammaging by targeting advanced glycation end products

    • Principal Investigator
      西中 崇
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Kindai University
  •  運動介入による再生、修復促進効果の新しい機序の解析研究

    • Principal Investigator
      高橋 英夫
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kindai University
  •  Homeostatic effect of improvement candidate drug targeting IL-33

    • Principal Investigator
      Hatipoglu Omer Faruk
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Kindai University
  •  Elucidation of the vasoprotective mechanism of sepsis-associated DAMPs antagonist HRGPrincipal Investigator

    • Principal Investigator
      Wake Hidenori
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Kindai University
  •  Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.

    • Principal Investigator
      Teshigawara Kiyoshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Okayama University
  •  Analysis dynamics of HMGB1 as a biosensor molecule and its multiple functions

    • Principal Investigator
      Nishibori Masahiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Okayama University
  •  Elucidation of an inhibitory mechanism of septic immunothrombosis by novel plasma factor:HRGPrincipal Investigator

    • Principal Investigator
      Wake Hidenori
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Okayama University
  •  Functional characterization of histidine-rich glycoprotein (HRG) under the inflammatory conditions.

    • Principal Investigator
      Teshigawara Kiyoshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  Functional analysis of HMGB1 as an inflammatory mediator in periodontitis

    • Principal Investigator
      YAMASHIRO KEISUKE
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Periodontology
    • Research Institution
      Okayama University
  •  Mechanism for microthrombus formation on NETosis and development of therapy for ARDS.

    • Principal Investigator
      Nishibori Masahiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Okayama University
  •  A novel pathological mechanism of Alzheimer's disease as a chronic inflammation through RAGE signal activity.

    • Principal Investigator
      Teshigawara Kiyoshi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Okayama University
  •  Drug development for brain and spinal cord trauma targeting HMGB1

    • Principal Investigator
      NISHIBORI Masahiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Okayama University
  •  Development oftherapy for acute traumatic brain injury

    • Principal Investigator
      NISHIBORI Masahiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Okayama University
  •  The development of broad-spectrum antitumor agents with anti-HMGB1 antibody and clarification of its action mechanismPrincipal Investigator

    • Principal Investigator
      WAKE HIDENORI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Okayama University
  •  Mechanism for HMGB-or HMGB1-derived peptide-induced increase in BBB permeability

    • Principal Investigator
      NISHIBORI Masahiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Okayama University
  •  Development of monoclonal antibodies therapy for cerebral infarction and cerebral edema

    • Principal Investigator
      RYU Katsuyaku
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Okayama University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent

  • [Journal Article] Histamine promotes angiogenesis through a histamine H1 receptor-PKC-VEGF-mediated pathway in human endothelial cells2023

    • Author(s)
      Hatipoglu Omer Faruk、Nishinaka Takashi、Nishibori Masahiro、Watanabe Masahiro、Toyomura Takao、Mori Shuji、Yaykasli Kursat Oguz、Wake Hidenori、Takahashi Hideo
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 151 Issue: 4 Pages: 177-186

    • DOI

      10.1016/j.jphs.2023.02.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15354, KAKENHI-PROJECT-21K06588
  • [Journal Article] Different modulation of STING/TBK1/IRF3 signaling by advanced glycation end products2023

    • Author(s)
      Nishinaka Takashi、Hatipoglu Omer Faruk、Wake Hidenori、Watanabe Masahiro、Toyomura Takao、Mori Shuji、Nishibori Masahiro、Takahashi Hideo
    • Journal Title

      Archives of Biochemistry and Biophysics

      Volume: 750 Pages: 109808-109808

    • DOI

      10.1016/j.abb.2023.109808

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K10465, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K15354
  • [Journal Article] Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway2023

    • Author(s)
      Toyomura Takao、Watanabe Masahiro、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
    • Journal Title

      Molecular Biology Reports

      Volume: 50 Issue: 7 Pages: 5849-5858

    • DOI

      10.1007/s11033-023-08509-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K10465, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06657, KAKENHI-PROJECT-21K06701
  • [Journal Article] Cationic ribosomal proteins can inhibit pro‐inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products2023

    • Author(s)
      Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
    • Journal Title

      Biotechnology and Applied Biochemistry

      Volume: 71 Issue: 2 Pages: 264-271

    • DOI

      10.1002/bab.2538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06657, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
  • [Journal Article] Glycolaldehyde-derived advanced glycation end products suppress STING/TBK1/IRF3 signaling via CD362022

    • Author(s)
      Nishinaka Takashi、Hatipoglu Omer Faruk、Wake Hidenori、Watanabe Masahiro、Toyomura Takao、Mori Shuji、Nishibori Masahiro、Takahashi Hideo
    • Journal Title

      Life Sciences

      Volume: 310 Pages: 121116-121116

    • DOI

      10.1016/j.lfs.2022.121116

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K15354
  • [Journal Article] Identification of ribosomal protein L9 as a novel regulator of proinflammatory damage-associated molecular pattern molecules2022

    • Author(s)
      Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
    • Journal Title

      Molecular Biology Reports

      Volume: 49 Issue: 4 Pages: 2831-2838

    • DOI

      10.1007/s11033-021-07096-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
  • [Journal Article] Role of histidine-rich glycoprotein as anti-DAMPs and therapeutic effects on DAMPs-related diseases2022

    • Author(s)
      Wake Hidenori
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 157 Issue: 6 Pages: 426-428

    • DOI

      10.1254/fpj.22074

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Journal Article] Central high mobility group box-1 induces mechanical hypersensitivity with spinal microglial activation in a mouse model of hemi-Parkinson’s disease2022

    • Author(s)
      Sato Fumiaki、Nakamura Yoki、Ma Simeng、Kochi Takahiro、Hisaoka-Nakashima Kazue、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Morioka Norimitsu
    • Journal Title

      Biomedicine & Pharmacotherapy

      Volume: 145 Pages: 112479-112479

    • DOI

      10.1016/j.biopha.2021.112479

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K18476, KAKENHI-PROJECT-19H03408
  • [Journal Article] Nordihydroguaiaretic acid inhibits glyoxalase I, and causes the accumulation of methylglyoxal followed by cell-growth inhibition2022

    • Author(s)
      Watanabe Masahiro、Toyomura Takao、Ikegami Ryo、Suwaki Yui、Sada Minami、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
    • Journal Title

      Molecular Biology Reports

      Volume: 49 Issue: 11 Pages: 10499-10507

    • DOI

      10.1007/s11033-022-07929-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
  • [Journal Article] Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A.2021

    • Author(s)
      Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
    • Journal Title

      J Immunol.

      Volume: 206(4) Issue: 4 Pages: 737-750

    • DOI

      10.4049/jimmunol.2000817

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-16H06277
  • [Journal Article] Pretreatment with High Mobility Group Box-1 Monoclonal Antibody Prevents the Onset of Trigeminal Neuropathy in Mice with a Distal Infraorbital Nerve Chronic Constriction Injury2021

    • Author(s)
      Kochi Takahiro、Nakamura Yoki、Ma Simeng、Hisaoka-Nakashima Kazue、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Irifune Masahiro、Morioka Norimitsu
    • Journal Title

      Molecules

      Volume: 26 Issue: 7 Pages: 2035-2035

    • DOI

      10.3390/molecules26072035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K18476, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K10139
  • [Journal Article] Perineural high-mobility group box 1 induces mechanical hypersensitivity through activation of spinal microglia: involvement of glutamate-NMDA receptor dependent mechanism in spinal dorsal horn.2021

    • Author(s)
      Nakamura Y, Fukuta A, Miyashita K, Zhang FF, Wang D, Liu K, Wake H, Hisaoka-Nakashima K, Nishibori M, Morioka N
    • Journal Title

      Biochem Pharmacol

      Volume: 186 Pages: 114496-114496

    • DOI

      10.1016/j.bcp.2021.114496

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07291, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K18476
  • [Journal Article] Involvement of multiple scavenger receptors in advanced glycation end product-induced vessel tube formation in endothelial cells2021

    • Author(s)
      Yamazaki Yui、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Liu Keyue、Watanabe Masahiro、Toyomura Takao、Mori Shuji、Yoshino Tadashi、Nishibori Masahiro、Takahashi Hideo
    • Journal Title

      Experimental Cell Research

      Volume: 408 Issue: 1 Pages: 112857-112857

    • DOI

      10.1016/j.yexcr.2021.112857

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07290, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K15354
  • [Journal Article] Osteopontin silencing attenuates bleomycin-induced murine pulmonary fibrosis by regulating epithelial-mesenchymal transition2021

    • Author(s)
      Hatipoglu OF, Uctepe E, Opoku G, Wake H, Ikemura K, Ohtsuki T, Inagaki J, Gunduz M, Gunduz E, Watanabe S, Nishinaka T, Takahashi H, Hirohata S.
    • Journal Title

      Biomed Pharmacother

      Volume: 139 Pages: 111633-111633

    • DOI

      10.1016/j.biopha.2021.111633

    • NAID

      120007099347

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K11791, KAKENHI-PROJECT-20H00548, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K15354
  • [Journal Article] Various functions of plasma histidine-rich glycoprotein and its clinical application as the biomarker and therapeutic drug for sepsis2020

    • Author(s)
      Wake Hidenori、Nishibori Masahiro
    • Journal Title

      Folia Pharmacologica Japonica

      Volume: 155 Issue: 3 Pages: 155-158

    • DOI

      10.1254/fpj.19150

    • NAID

      130007839043

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Journal Article] Advanced glycation end products (AGEs) synergistically potentiated the proinflammatory action of lipopolysaccharide (LPS) and high mobility group box-1 (HMGB1) through their direct interactions.2020

    • Author(s)
      Watanabe M, Toyomura T, Tomiyama M, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S.
    • Journal Title

      Mol Biol Rep.

      Volume: 47(9) Issue: 9 Pages: 7153-7159

    • DOI

      10.1007/s11033-020-05783-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-18K06807, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-18K14969
  • [Journal Article] Cystitis-Related Bladder Pain Involves ATP-Dependent HMGB1 Release from Macrophages and Its Downstream H2S/Cav3.2 Signaling in Mice2020

    • Author(s)
      Hiramoto Shiori、Tsubota Maho、Yamaguchi Kaoru、Okazaki Kyoko、Sakaegi Aya、Toriyama Yuki、Tanaka Junichi、Sekiguchi Fumiko、Ishikura Hiroyasu、Wake Hidenori、Nishibori Masahiro、Nguyen Huy Du、Okada Takuya、Toyooka Naoki、Kawabata Atsufumi
    • Journal Title

      Cells

      Volume: 9 Issue: 8 Pages: 1748-1748

    • DOI

      10.3390/cells9081748

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Journal Article] Cav3.2 overexpression in L4 dorsal root ganglion neurons after L5 spinal nerve cutting involves Egr-1, USP5 and HMGB1 in rats: An emerging signaling pathway for neuropathic pain2020

    • Author(s)
      Tomita Shiori、Sekiguchi Fumiko、Kasanami Yoshihito、Naoe Katsuki、Tsubota Maho、Wake Hidenori、Nishibori Masahiro、Kawabata Atsufumi
    • Journal Title

      European Journal of Pharmacology

      Volume: 888 Pages: 173587-173587

    • DOI

      10.1016/j.ejphar.2020.173587

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Journal Article] Histidine-rich glycoprotein possesses antioxidant activity through self-oxidation and inhibition of hydroxyl radical production via chelating divalent metal ions in Fenton's reaction.2020

    • Author(s)
      Wake H, Takahashi Y, Yoshii Y, Gao S, Mori S, Wang D, Teshigawara K, Nishibori M.
    • Journal Title

      Free Radic Res.

      Volume: 54(8-9) Issue: 8-9 Pages: 649-661

    • DOI

      10.1080/10715762.2020.1825703

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Journal Article] Corticosterone Induces HMGB1 Release in Primary Cultured Rat Cortical Astrocytes: Involvement of Pannexin-1 and P2X7 Receptor-Dependent Mechanisms2020

    • Author(s)
      Hisaoka-Nakashima Kazue、Azuma Honami、Ishikawa Fumina、Nakamura Yoki、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Nakata Yoshihiro、Morioka Norimitsu
    • Journal Title

      Cells

      Volume: 9 Issue: 5 Pages: 1068-1068

    • DOI

      10.3390/cells9051068

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408
  • [Journal Article] High Mobility Group Box-1 and Blood Brain Barrier Disruption2020

    • Author(s)
      Nishibori Masahiro、Wang Dengli、Ousaka Daiki、Wake Hidenori
    • Journal Title

      Cells

      Volume: 9 Issue: 12 Pages: 2650-2650

    • DOI

      10.3390/cells9122650

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408
  • [Journal Article] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes2020

    • Author(s)
      Wang Dengli、Liu Keyue、Fukuyasu Yusuke、Teshigawara Kiyoshi、Fu Li、Wake Hidenori、Ohtsuka Aiji、Nishibori Masahiro
    • Journal Title

      Cells

      Volume: 9 Issue: 3 Pages: 643-643

    • DOI

      10.3390/cells9030643

    • NAID

      120006860110

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Journal Article] An Evaluation of the Activity of Histidine-Rich Glycoprotein on Differentiated Neutrophil-Like Cells from Human Cell Lines.2020

    • Author(s)
      Yoshii Y, Wake H, Nishimura Y, Teshigawara K, Wang D, Nishibori M.
    • Journal Title

      J Pharmacol Exp Ther.

      Volume: 375(3) Issue: 3 Pages: 406-413

    • DOI

      10.1124/jpet.120.000182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Journal Article] Histidine-Rich Glycoprotein Inhibits High-Mobility Group Box-1-Mediated Pathways in Vascular Endothelial Cells through CLEC-1A2020

    • Author(s)
      Gao Shangze、Wake Hidenori、Sakaguchi Masakiyo、Wang Dengli、Takahashi Youhei、Teshigawara Kiyoshi、Zhong Hui、Mori Shuji、Liu Keyue、Takahashi Hideo、Nishibori Masahiro
    • Journal Title

      iScience

      Volume: 23 Issue: 6 Pages: 101180-101180

    • DOI

      10.1016/j.isci.2020.101180

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-16H06277
  • [Journal Article] Spinal high-mobility group box-1 induces long-lasting mechanical hypersensitivity through the toll-like receptor 4 and upregulation of interleukin-1β in activated astrocytes.2019

    • Author(s)
      Morioka N, Miyauchi K, Miyashita K, Kochi T, Zhang FF, Nakamura Y, Liu K, Wake H, Hisaoka-Nakashima K, Nishibori M, Nakata Y.
    • Journal Title

      J Neurochem

      Volume: 150 Issue: 6 Pages: 738-58

    • DOI

      10.1111/jnc.14812

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Journal Article] Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B2019

    • Author(s)
      Nishimura Yoshito、Wake Hidenori、Teshigawara Kiyoshi、Wang Dengli、Sakaguchi Masakiyo、Otsuka Fumio、Nishibori Masahiro
    • Journal Title

      Pharmacology Research & Perspectives

      Volume: 7 Issue: 3

    • DOI

      10.1002/prp2.481

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-17H03577
  • [Journal Article] Differential contribution of possible pattern‐recognition receptors to advanced glycation end product?induced cellular responses in macrophage‐like RAW264.7 cells2019

    • Author(s)
      Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Liu Keyue、Teshigawara Kiyoshi、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
    • Journal Title

      Biotechnology and Applied Biochemistry

      Volume: in press Issue: 2 Pages: 265-272

    • DOI

      10.1002/bab.1843

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-18K14969, KAKENHI-PROJECT-18K06807
  • [Journal Article] Histidine-rich Glycoprotein Modulates the Blood-vascular System in Septic Condition2019

    • Author(s)
      Wake Hidenori
    • Journal Title

      Acta Medica Okayama

      Volume: 73 Issue: 5 Pages: 379-382

    • DOI

      10.18926/AMO/57366

    • NAID

      120006732619

    • URL

      https://ousar.lib.okayama-u.ac.jp/57366

    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Journal Article] Role of non-macrophage cell-derived HMGB1 in oxaliplatin-induced peripheral neuropathy and its prevention by the thrombin/thrombomodulin system in rodents: negative impact of anticoagulants2019

    • Author(s)
      Tsubota Maho、Fukuda Ryotaro、Hayashi Yusuke、Miyazaki Takaya、Ueda Shin、Yamashita Rika、Koike Nene、Sekiguchi Fumiko、Wake Hidenori、Wakatsuki Shuji、Ujiie Yuka、Araki Toshiyuki、Nishibori Masahiro、Kawabata Atsufumi
    • Journal Title

      Journal of Neuroinflammation

      Volume: 16 Issue: 1 Pages: 199-199

    • DOI

      10.1186/s12974-019-1581-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06710, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-17K09046, KAKENHI-PROJECT-17K19945, KAKENHI-PROJECT-16H06276
  • [Journal Article] Histidine-rich glycoprotein ameliorates endothelial barrier dysfunction through regulation of NF-κB and MAPK signal pathway2019

    • Author(s)
      Gao S, Wake H, Gao Y, Wang D, Mori S, Liu K, Teshigawara K, Takahashi H, Nishibori M
    • Journal Title

      Br J Pharmacol.

      Volume: 176 Issue: 15 Pages: 2808-2824

    • DOI

      10.1111/bph.14711

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-17K15580
  • [Journal Article] Histidine-Rich Glycoprotein Suppresses Hyperinflammatory Responses of Lung in a Severe Acute Pancreatitis Mouse Model2018

    • Author(s)
      Terao K, Wake H, Adachi N, Liu K, Teshigawara K, Takahashi H, Mori S, Nishibori M
    • Journal Title

      Pancreas

      Volume: 47 Issue: 9 Pages: 1156-1164

    • DOI

      10.1097/mpa.0000000000001153

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-17K15580, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
  • [Journal Article] Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis.2018

    • Author(s)
      Kobori T, Hamasaki S, Kitaura A, Yamazaki Y, Nishinaka T, Niwa A, Nakao S, Wake H, Mori S, Yoshino T, Nishibori M, Takahashi H
    • Journal Title

      Frontiers in Immunology

      Volume: 9 Pages: 334-334

    • DOI

      10.3389/fimmu.2018.00334

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01881, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H07272, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K18996, KAKENHI-PROJECT-18K15035
  • [Journal Article] Decrease in histidine-rich glycoprotein as a novel biomarker to predict sepsis amongsystemic inflammatory response syndrome.2018

    • Author(s)
      Kuroda K, Wake H, Mori S, Hinotsu S, Nishibori M, Morimatsu H.
    • Journal Title

      Critical Care Medicine

      Volume: 46 Issue: 4 Pages: 570-576

    • DOI

      10.1097/ccm.0000000000002947

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Journal Article] The C‐terminal region of tumor necrosis factor like weak inducer of apoptosis is required for interaction with advanced glycation end products2018

    • Author(s)
      Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Liu Keyue、Teshigawara Kiyoshi、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
    • Journal Title

      Biotechnology and Applied Biochemistry

      Volume: 66 Issue: 2 Pages: 254-260

    • DOI

      10.1002/bab.1706

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K14969, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-18K06807
  • [Journal Article] Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions.2018

    • Author(s)
      Zhong H, Wake H, Liu K, Gao Y, Teshigawara K, Sakaguchi M, Mori S, Nishibori M.
    • Journal Title

      J Pharmacol Sci.

      Volume: 136(3) Issue: 3 Pages: 97-106

    • DOI

      10.1016/j.jphs.2017.11.003

    • NAID

      130007902144

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17K15580
  • [Journal Article] Anti-HMGB1 Neutralizing Antibody Attenuates Periodontal Inflammation and Bone Resorption in a Murine Periodontitis Model2018

    • Author(s)
      Yoshihara-Hirata Chiaki、Yamashiro Keisuke、Yamamoto Tadashi、Aoyagi Hiroaki、Ideguchi Hidetaka、Kawamura Mari、Suzuki Risa、Ono Mitsuaki、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
    • Journal Title

      Infection and Immunity

      Volume: 86 Issue: 5

    • DOI

      10.1128/iai.00111-18

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050, KAKENHI-PROJECT-16K11624
  • [Journal Article] Histidine-rich glycoprotein as an excellent biomarker for sepsis and beyond2018

    • Author(s)
      Nishibori Masahiro、Wake Hidenori、Morimatsu Hiroshi
    • Journal Title

      Critical Care

      Volume: 22 Issue: 1 Pages: 209-209

    • DOI

      10.1186/s13054-018-2127-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Journal Article] Anti-High Mobility Group Box 1 Antibody Therapy May Prevent Cognitive Dysfunction After Traumatic Brain Injury2018

    • Author(s)
      Okuma Y, Wake H, Teshigawara K, Takahashi Y, Hishikawa T, Yasuhara T, Mori S, Takahashi HK, Date I, Nishibori M
    • Journal Title

      World neurosurgery

      Volume: 122 Pages: 119-123

    • DOI

      10.1016/j.wneu.2018.10.164

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-19K09508, KAKENHI-PROJECT-19K09528, KAKENHI-PROJECT-17H04303
  • [Journal Article] Inter-α inhibitor proteins maintain neutrophils in a resting state by regulating shape and reducing ROS production.2018

    • Author(s)
      Htwe SS, Wake H, Liu K, Teshigawara K, Stonestreet BS, Lim YP, Nishibori M.
    • Journal Title

      Blood Adv.

      Volume: 2(15) Issue: 15 Pages: 1923-1934

    • DOI

      10.1182/bloodadvances.2018018986

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
  • [Journal Article] HMGB1-induced inflammatory response promotes bone healing in murine tooth extraction socket2018

    • Author(s)
      Aoyagi Hiroaki、Yamashiro Keisuke、Hirata-Yoshihara Chiaki、Ideguchi Hidetaka、Yamasaki Mutsuyo、Kawamura Mari、Yamamoto Tadashi、Kochi Shinsuke、Wake Hidenori、Nishibori Masahiro、Takashiba Shogo
    • Journal Title

      Journal of Cellular Biochemistry

      Volume: - Issue: 7 Pages: 5481-5490

    • DOI

      10.1002/jcb.26710

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06994, KAKENHI-PROJECT-16K20670, KAKENHI-PROJECT-18K17050
  • [Journal Article] Anti-high mobility group box-1 (HMGB1) antibody inhibits hemorrhage-induced brain injury and improved neurological deficits in rats.2017

    • Author(s)
      Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
    • Journal Title

      Sci Rep.

      Volume: 7:46243. Issue: 1 Pages: 46243-46243

    • DOI

      10.1038/srep46243

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
  • [Journal Article] Advanced glycation end products attenuate the function of tumor necrosis factor-like weak inducer of apoptosis to regulate the inflammatory response2017

    • Author(s)
      Watanabe M, Toyomura T, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S
    • Journal Title

      Molecular and Cellular Biochemistry

      Volume: 印刷中 Issue: 1-2 Pages: 153-162

    • DOI

      10.1007/s11010-017-3045-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H06785, KAKENHI-PROJECT-15K08605, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15K08253
  • [Journal Article] The specific localization of advanced glycation end-products (AGEs) in rat pancreatic islets.2017

    • Author(s)
      Morioka Y, Teshigawara K, Tomono Y, Wang D, Izushi Y, Wake H, Liu K, Takahashi HK, Mori S, Nishibori M.
    • Journal Title

      J Pharmacol Sci.

      Volume: 134(4) Issue: 4 Pages: 218-224

    • DOI

      10.1016/j.jphs.2017.07.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K08605
  • [Journal Article] Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.2017

    • Author(s)
      Fu L, Liu K, Wake H, Teshigawara K, Yoshino T, Takahashi H, Mori S, Nishibori M.
    • Journal Title

      Sci Rep.

      Volume: 7(1):1179. Issue: 1 Pages: 1179-1179

    • DOI

      10.1038/s41598-017-01325-y

    • NAID

      130007901378

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15K08253
  • [Journal Article] Phagocytosis of Advanced Glycation End Products (AGEs) in Macrophages Induces Cell Apoptosis.2017

    • Author(s)
      Gao Y, Wake H, Morioka Y, Liu K, Teshigawara K, Shibuya M, Zhou J, Mori S, Takahashi H, Nishibori M.
    • Journal Title

      Oxid Med Cell Longev.

      Volume: 2017:8419035 Issue: 1 Pages: 8419035-8419035

    • DOI

      10.1155/2017/8419035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K08605
  • [Journal Article] Anti-high mobility group box-1 (HMGB1) antibody attenuates delayed cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats2016

    • Author(s)
      Haruma J, Teshigawara K, Hishikawa T, Wang D, Liu K, Wake H, Mori S, Takahashi HK, Sugiu K, Date I, Nishibori M.
    • Journal Title

      Scientific reports

      Volume: 6 Issue: 1 Pages: 37755-37768

    • DOI

      10.1038/srep37755

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909
  • [Journal Article] Histidine-rich glycoprotein prevents septic lethality through regulation of immunothrombosis and inflammation.2016

    • Author(s)
      Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakaguchi M, Kuroda K, Gao Y, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H, Nishibori M.
    • Journal Title

      EBioMedicine

      Volume: 9 Pages: 180-194

    • DOI

      10.1016/j.ebiom.2016.06.003

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232
  • [Journal Article] Soluble form of the receptor for advanced glycation end-products attenuates inflammatory pathogenesis in a rat model of lipopolysaccharide-induced lung injury.2016

    • Author(s)
      Izushi Y, Teshigawara K, Liu K, Wang D, Wake H, Takata K, Yoshino T, Takahashi HK, Mori S, Nishibori M.
    • Journal Title

      J Pharmacol Sci.

      Volume: S1347-8613(16)00026-8. Issue: 4 Pages: 1-9

    • DOI

      10.1016/j.jphs.2016.02.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232
  • [Journal Article] Voluntary exercise induces neurogenesis in the hypothalamus and ependymal lining of the third ventricle.2015

    • Author(s)
      Niwa A, Nishibori M, Hamasaki S, Kobori T, Liu K, Wake H, Mori S, Yoshino T, Takahashi H.
    • Journal Title

      Brain Structure & Function

      Volume: 印刷中 Issue: 3 Pages: 1863-2653

    • DOI

      10.1007/s00429-015-0995-x

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-26350918
  • [Journal Article] Glycyrrhizin inhibits traumatic brain injury by reducing HMGB1-RAGE interaction.2014

    • Author(s)
      OkumaY, Liu K, Wake H, Liu R, Nishimura Y, Zhong H, Teshigawara K, Haruma J, Yamamoto Y, Yamamoto H, Date I, Takahashi HK, Mori S, Nishibori M.
    • Journal Title

      Neuropharmacology

      Volume: 85 Pages: 18-26

    • DOI

      10.1016/j.neuropharm.2014.05.007

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-25461335, KAKENHI-PROJECT-25670464, KAKENHI-PROJECT-26293323
  • [Journal Article] Histamine inhibits high mobility group box 1-induced adhesion molecule expression on human monocytes2013

    • Author(s)
      Takahashi H、Sadamori H、Teshigawara K、Niwa A、Liu K、Wake H、Mori S、Yoshino T、Nishibori M
    • Journal Title

      Eur J Phamacol

      Volume: Vol.718、No.1-3 Issue: 1-3 Pages: 305-313

    • DOI

      10.1016/j.ejphar.2013.08.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591864, KAKENHI-PROJECT-23790601, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PROJECT-24590672, KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-25461947, KAKENHI-PROJECT-25670464
  • [Journal Article] Role of cell-cell interactions in high mobility group box 1 cytokine activity in human peripheral blood mononuclear cells and mouse splenocytes2013

    • Author(s)
      Kohka Takahashi H, Sadamori H, Liu K, Wake H, Mori S, Yoshino T, Yamamoto Y, Yamamoto H, Nishibori M
    • Journal Title

      European Journal of Pharmacology

      Volume: 701(1-3) Issue: 1-3 Pages: 194-202

    • DOI

      10.1016/j.ejphar.2012.11.058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591864, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-24590672
  • [Journal Article] Anti-high mobility group box-1 antibody therapy for traumatic brain injury2012

    • Author(s)
      Okuma Y, Liu K, Wake H, Zhang J, Maruo T, Date I, Yoshino T, Ohtsuka A, Otani N, Tomura S, Shima K, Yamamoto Y, Yamamoto H, Takahashi H K, Mori S, Nishibori M
    • Journal Title

      Annals of Neurology

      Volume: 72 Issue: 3 Pages: 373-384

    • DOI

      10.1002/ana.23602

    • NAID

      130004427993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390349, KAKENHI-PROJECT-23659430, KAKENHI-PROJECT-23659687, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PROJECT-24590658, KAKENHI-PROJECT-24590672
  • [Journal Article] Anti-High Mobility Group Box-1 Antibody Therapy for Traumatic Brain Injury2012

    • Author(s)
      Okuma Y., Liu K., Wake H., Zhang J., Maruo T., Date I., Yoshio T., Ohtsuka A., Otani N., Tomura S., Shima K., Yamamoto Y., Yamamoto H., Takahashi H., Mori S.,Nishibori M
    • Journal Title

      Annals of Neurology

      Volume: in press

    • NAID

      130004427993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Journal Article] Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood-Brain Barrier from Ischemia-Induced Disruption in Rats.2011

    • Author(s)
      Zhang J, Liu K, Wake H, Nishibori M. et al.(11名、11番目)
    • Journal Title

      Stroke

      Volume: 42(5) Pages: 1420-1428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats2011

    • Author(s)
      Zhang J, Takahashi HK, Liu K, Wake H, Liu R, Maruo T, Date I, Yoshino T, Ohtsuka A, Mori S, Nishibori M
    • Journal Title

      Stroke

      Volume: 42(5) Pages: 1420-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Anti-high Mobility Group Box-1 Monoclonal Antibody Protects the Blood-Brain Barrier from Ischemia-Induced Disruption in Rats.2011

    • Author(s)
      Zhang J, Takahashi HK, Liu K, Wake K, Liu R, Maruo T, Date I, Yoshino T, Ohtsuka A, Mori S, Nishibori M.
    • Journal Title

      Stroke

      Volume: 42(5) Pages: 1420-1428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Journal Article] Beta2-adrenoceptor stimulation inhibits advanced glycation end products-induced adhesion molecule expression and cytokine production in human peripheral bloodmononuclear cells2010

    • Author(s)
      Takahashi HK, Mori S, Liu K, Wake H, Zhang J, Liu R, Yoshino T, Nishibori M
    • Journal Title

      Eur J Pharmacol

      Volume: 627(1-3) Pages: 313-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Histamine inhibits adhesion molecule expression in human monocytes, induced by advanced glycation end products, during the mixed lymphocyte reaction.2010

    • Author(s)
      Zhang J, Liu K, Wake H, Nishibori M., et al.(11名、11番目)
    • Journal Title

      Br J Pharmacol

      Volume: 160 Pages: 1378-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Effect of nicotine on advanced glycation end product-induced immune response in human monocytes2010

    • Author(s)
      Takahashi HK, Liu K, Wake H, Nishibori M, et al., (8名、8番目)
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 332 Pages: 1013-1021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Prostaglandin E2 inhibits advanced glycation end product induced adhesion molecule expression on monocytes, cytokine production, and lymphocyte proliferation during human mixed lymphocyte reaction2010

    • Author(s)
      Takahashi HK, Zhang J, Mori S, Liu K, Wake H, Liu R, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 34(3) Pages: 964-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Advanced glycation end products enhance monocyte activation during human mixedlymphocyte reaction2010

    • Author(s)
      Ohashi K, Takahashi HK, Mori S, Liu K, Wake H, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M, Tanaka N
    • Journal Title

      Clin Immunol

      Volume: 134(3) Pages: 345-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Ciprofloxacin inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.2010

    • Author(s)
      Mori S, Liu K, Wake H, Nishibori M., et al.(8名、8番目)
    • Journal Title

      Br J Pharmacol

      Volume: 161 Pages: 229-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression on monocytes, cytokine production, and lymphocyte proliferation during human mixed lymphocyte reaction.2010

    • Author(s)
      Takahashi HK, Liu K, Wake H, Nishibori M., et al.(11名、11番目)
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 334 Pages: 964-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Advanced glycation end products enhance monocyte activation during human mixed lymphocyte reaction.2010

    • Author(s)
      Ohashi K, Liu K, Wake H, Nishibori M, et al., (11名、10番目)
    • Journal Title

      Clin Immunol

      Volume: 134 Pages: 345-353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Anti-Sp100 antibody2010

    • Author(s)
      Mori S, Wake H, Liu K, Takahashi HK, Nishibori M
    • Journal Title

      Nihon Rinsho

      Volume: 68 Suppl 6 Pages: 711-3

    • NAID

      40017181877

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Effect of nicotine on advanced glycation end product-induced immune response in humanmonocytes2010

    • Author(s)
      Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 332(3) Pages: 1013-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts : heparin's effect on binding.2009

    • Author(s)
      Liu R, Mori S, Wake H, Zhang J, Liu K, Izushi Y, Takahashi HK, Peng B, Nishibori M.
    • Journal Title

      Acta Med Okayama. 63(4)

      Pages: 203-211

    • NAID

      120002312782

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2009

    • Author(s)
      Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M.
    • Journal Title

      J Pharmacol Exp Ther 330(1)

      Pages: 89-98

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells2009

    • Author(s)
      Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 331(2) Pages: 656-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Prostaglandins E2 inhibits advanced glycation end products-induced adhesion molecule expression, cytokine production and lymphocyte proliferation in human peripheral blood mononuclear cells2009

    • Author(s)
      Takahashi HK, Liu K, Wake H, Nishibori M, et al., (8名、8番目)
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 331 Pages: 656-670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.2009

    • Author(s)
      Wake H
    • Journal Title

      J Pharmacol Exp Ther. 330

      Pages: 826-830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes2009

    • Author(s)
      Wake H, Takahashi HK, Mori S, Liu K, Yoshino T, Nishibori M
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 330(3) Pages: 826-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells.2009

    • Author(s)
      Takahashi HK, Wake H, Liu K, Nishibori M, et al., (10名、10番目)
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 330 Pages: 89-98

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells2009

    • Author(s)
      Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 330(1) Pages: 89-98

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes.2009

    • Author(s)
      Wake H, Takahashi HK, Liu K, Nishibori M, et al., (6名、6番目)
    • Journal Title

      J. Pharmacol Exp Ther

      Volume: 330 Pages: 826-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Journal Article] Establishment of in vitro binding assay of high mobility group box-1 and S100A12 to receptor for advanced glycation endproducts : heparin's effect on binding2009

    • Author(s)
      Liu R, Mori S, Wake H, Zhang J, Liu K, Izushi Y, Takahashi HK, Peng B, Nishibori M
    • Journal Title

      Acta Med Okayama

      Volume: 63(4) Pages: 203-11

    • NAID

      120002312782

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] High mobility group box 1 complexed with heparin induced angiogenesis in a matrigelplug assay2009

    • Author(s)
      Wake H, Mori S, Liu K, Takahashi HK, Nishibori M
    • Journal Title

      Acta Med Okayama

      Volume: 63(5) Pages: 249-62

    • NAID

      120002312983

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Histidine-rich glycoprotein inhibited high mobility group box 1 in complex with heparin-induced angiogenesis in matrigel plug assay2009

    • Author(s)
      Wake H, Mori S, Liu K, Takahashi HK, Nishibori M
    • Journal Title

      Eur J Pharmacol

      Volume: 623(1-3) Pages: 89-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Journal Article] Anti-High Mobility Group Box-1 Antibody Therapy for Traumatic Brain Injury

    • Author(s)
      Okuma Y., Liu K., Wake H., Nishibori M., et al.(16名、16番目)
    • Journal Title

      Annals of Neurology

      Volume: (in press)

    • NAID

      130004427993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Patent] 活性酸素の産生抑制剤及び/又は消去促進剤2021

    • Inventor(s)
      西堀正洋、森秀治、和氣秀徳
    • Industrial Property Rights Holder
      西堀正洋、森秀治、和氣秀徳
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Patent] 赤血球保護剤2018

    • Inventor(s)
      西堀正洋、和氣秀徳、衷輝、森秀治、阪口政清
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Patent] 赤血球保護剤2018

    • Inventor(s)
      西堀正洋、和氣秀徳、衷輝、森秀治、阪口政清
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Patent] 赤血球保護剤2017

    • Inventor(s)
      西堀正洋、和氣秀徳、衷輝、森秀治、阪口政清
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-028738
    • Filing Date
      2017-02-20
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Patent] THERAPEUTIC AGENT, METHOD OF TREATMENT AND METHOD FOR PREDICTING THE SEVERITY OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME(SIRS), DISEASES CAUSED OR ACCOMPANIED BY NEUTROPHIL ACTIVATION2016

    • Inventor(s)
      西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約、勅使川原匡 他3名
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Patent] サイトカインストーム抑制剤2015

    • Inventor(s)
      西堀 正洋、森 秀治、和氣 秀徳
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-154972
    • Filing Date
      2015-08-05
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Patent] 好中球活性化に起因する疾患の治療薬及び検査方法2015

    • Inventor(s)
      西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約 ほか2名
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015
    • Acquisition Date
      2017
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Patent] サイトカインストーム抑制剤2015

    • Inventor(s)
      西堀 正洋、森 秀治、和氣 秀徳
    • Industrial Property Rights Holder
      岡山大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-12-21
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010

    • Inventor(s)
      西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
    • Industrial Property Rights Holder
      西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
    • Industrial Property Number
      2010-214019
    • Filing Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Patent] RAGEとAGEの結合抑制剤のスクリーニング方法2010

    • Inventor(s)
      西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約
    • Industrial Property Rights Holder
      国立大学法人岡山大学
    • Industrial Property Number
      2010-214019
    • Filing Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Patent] 外傷性神経障害治療剤2010

    • Inventor(s)
      西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
    • Industrial Property Rights Holder
      西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
    • Industrial Property Number
      2010-270133
    • Filing Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-21590594
  • [Patent] 外傷性神経障害治療剤2010

    • Inventor(s)
      西堀正洋、森秀治、高橋英夫、和氣秀徳、劉克約、伊達勲、大熊佑、友野靖子
    • Industrial Property Rights Holder
      国立大学法人岡山大学、医療法人創和会
    • Industrial Property Number
      2010-270133
    • Filing Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Presentation] Glycolaldehyde derived advanced glycation end products suppress STING signaling in macrophage2023

    • Author(s)
      西中崇、ハティポール オメル ファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K10465
  • [Presentation] 自然免疫シグナルSTINGの活性制御に対する終末糖化産物の関与2023

    • Author(s)
      西中崇、ハティポール オメル ファルク、和氣秀徳、渡邊政博、豊村隆男、森秀治、西堀正洋、高橋英夫
    • Organizer
      第143回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-23K10465
  • [Presentation] ヒスタミンは血管内皮細胞のH1受容体を介して管腔形成を促進する2023

    • Author(s)
      ハティポール オメル ファルク、西中 崇、西堀 正洋、渡邊 政博、豊村 隆男、森 秀治、和氣 秀徳、高橋 英夫
    • Organizer
      第55回日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K10465
  • [Presentation] ヒスタミンはEA.hy926血管内皮細胞のH1受容体を介して管腔形成を促進する2023

    • Author(s)
      ハティポール オメル ファルク、西中 崇、西堀 正洋、渡邊 政博、豊村 隆男、森 秀治、和氣 秀徳、高橋 英夫
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K10465
  • [Presentation] 高ヒスチジン糖タンパク質は好中球恒常性維持に寄与する多面的機能を有する2023

    • Author(s)
      和氣 秀徳、森 秀治、西堀 正洋、西中 崇、ハティポール オメル ファルク、髙橋 英夫
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K10465
  • [Presentation] TNFαはインテグリンα3-β8を介して血管内皮細胞の管腔形成を促進する2023

    • Author(s)
      ハティポール オメル ファルク、西中 崇、和氣 秀徳、西堀 正洋、渡邊 政博、豊村 隆男、森 秀治、高橋 英夫
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K10465
  • [Presentation] Histamine promotes tube formation of human vascular endothelial cells via H1 receptor2023

    • Author(s)
      ハティポール オメル ファルク、西中 崇、西堀 正洋、渡邊 政博、豊村 隆男、森 秀治、和氣 秀徳、高橋 英夫
    • Organizer
      第55回日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] Histamine promotes tube formation in human vascular endothelial cells(EA.hy926) by acting through the H1 receptor.2023

    • Author(s)
      ハティポール オメル ファルク、西中 崇、西堀 正洋、渡邊 政博、豊村 隆男、森 秀治、和氣 秀徳、高橋 英夫
    • Organizer
      第96 回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] TNFα Promotes Vascular Endothelial Cell Tube Formation via Integrin α3-β82023

    • Author(s)
      ハティポール オメル ファルク、西中 崇、西堀 正洋、渡邊 政博、豊村 隆男、森 秀治、和氣 秀徳、高橋 英夫
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] 終末糖化産物によるSTINGシグナルの調節はカルボニル化合物の種類や濃度に依存する2023

    • Author(s)
      西中 崇、ハティポール オメル ファルク、和氣 秀徳、渡邊 政博、豊村 隆男、森 秀治、西堀 正洋、高橋 英夫
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-23K10465
  • [Presentation] 血液系恒常性維持に密接に関与する多機能タンパク2023

    • Author(s)
      和氣 秀徳、西中 崇、ハティポール オメル ファルク、渡邊 政博、豊村 隆男、森 秀治、西堀 正洋、高橋 英夫
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K10465
  • [Presentation] 神経障害性疼痛マウスにおける認知機能傷害に対するHMGB1中和抗体の効果に関する検討2022

    • Author(s)
      吉本夏輝、中島一恵、大畑一努、中村庸輝、王登莉、劉克約、和氣秀徳、吾郷由希夫、西堀正洋、森岡徳光
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] Effect of advanced glycation end products on STING pathway in macrophage2022

    • Author(s)
      Takashi Nishinaka, Omer Faruk Hatipoglu, Hidenori Wake, Masahiro Watanabe, Takao Toyomura, Masahiro Nishibori, Hideo Takahashi
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] Long-term Advanced Glycation End Product 3 (AGE3) Stimulation Reduces Aggrecan and Type II Collagen Production in Human Chondrocytes2022

    • Author(s)
      Omer Faruk Hatipoglu, Takashi Nishinaka, Hidenori Wake, Shuji Mori, Masahiro Watanabe, Takao Toyomura, Hideo Takahashi
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] 終末糖化産物によるSTINGシグナルの調節2022

    • Author(s)
      西中 崇 、ハティポール オメル ファルク、和氣 秀徳 、渡邊 政博 、豊村 隆男 、森 秀治、西堀 正洋 、高橋 英夫
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] ヒスチジンに富む糖タンパク質の抗酸化能は、敗血症の病態生理の改善に寄与する2022

    • Author(s)
      和氣 秀徳 、森 秀治 、西堀 正洋 、ハティポール オメル ファルク 、西中 崇 、高橋 英夫
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] 血漿タンパクHRGは敗血症防止と生体恒常性維持に働く重要な因子である2022

    • Author(s)
      西堀 正洋、和氣 秀徳、阪口 政清
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Presentation] ヒスタミンは血管内皮細胞の管腔形成を促進する2022

    • Author(s)
      ハティポール オメル ファルク、西中 崇、西堀 正洋、渡邊 政博、豊村 隆男、森 秀治、和氣 秀徳、高橋 英夫
    • Organizer
      第37回 創薬・薬理フォーラム岡山
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] Anti-DAMPsタンパク質HRGの敗血症治療薬としての可能性とDAMPs関連病態への応用2022

    • Author(s)
      和氣 秀徳
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Presentation] ヒスタミンは血管内皮細胞の管腔形成を促進する2022

    • Author(s)
      ハティポール オメル ファルク、西中 崇、西堀 正洋、渡邊 政博、豊村 隆男、森 秀治、和氣 秀徳、高橋 英夫
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] 高ヒスチジン糖タンパク質の抗酸化能は敗血症病態改善に寄与する2022

    • Author(s)
      和氣 秀徳、森 秀治、西堀 正洋、ハティポール オメル ファルク、西中 崇、高橋 英夫
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Presentation] パーキンソン病における痛覚過敏へのhigh mobility group box-1中和抗体の抑制効果2021

    • Author(s)
      佐藤史爽、中村庸輝、麻思萌、河内貴弘、中島一恵、王登莉、劉克約、和氣秀徳、西堀正洋、森岡徳光
    • Organizer
      第94回日本薬理学会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] マウス周産期における血漿高ヒスチジン糖タンパクの生理的動態解析2021

    • Author(s)
      勅使川原匡、劉克約、王登莉、和氣秀徳、森秀治、髙橋英夫、西堀正洋
    • Organizer
      第94回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] ADAMTS5の発現はヒト軟骨肉腫細胞において NF-κβによって アップレギュレートされる2021

    • Author(s)
      Omer Faruk Hatipoglu, Bilgic Dilek Gun, Takashi Nishinaka. Hidenori Wake, Satoshi Hirohata, Hideo Takahashi
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] 敗血症病態改善作用を有する高ヒスチジン糖タンパク質の抗酸化能2021

    • Author(s)
      和氣 秀徳、森 秀治、西堀 正洋、西中 崇、ハティポール オメル ファルク、高橋 英夫
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Presentation] 終末糖化産物による LPS-HMGB1共刺激炎症応答の相乗的活性化作用2021

    • Author(s)
      森 秀治, 渡邊 政博, 和氣 秀徳, 西中 崇, ハティポール オメル ファルク, 高橋 英夫, 西堀 正洋, 豊村 隆男
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.2021

    • Author(s)
      Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Hidenori Wake, Shuji Mori, Hideo Kohka Takahashi, Masahiro Nishibori
    • Organizer
      The 22nd World Congress of International Society for the Study of Hypertension in Pregnancy (ISSHP2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 敗血症病態改善作用を有する高ヒスチジン糖タンパク質の抗酸化能2021

    • Author(s)
      和氣 秀徳, 森 秀治, 西堀 正洋, 西中 崇, ハティポール オメル ファルク, 高橋 英夫
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06588
  • [Presentation] マウス周産期における血漿高ヒスチジン糖タンパクの生理的動態解析2021

    • Author(s)
      勅使川原匡, 劉克約, 王登莉, 和氣秀徳, 森秀治, 高橋英夫, 西堀正洋
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Presentation] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes.2020

    • Author(s)
      王登莉、劉克約、勅使川原匡、和氣秀徳、西堀正洋
    • Organizer
      第137回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes.2020

    • Author(s)
      王登莉, 劉克約, 勅使川原匡, 和氣秀徳, 西堀正洋
    • Organizer
      第137回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Presentation] HMGB1 中和抗体の局所投与はマウス遠位眼窩下神経慢性絞扼により発生する顔面感覚異常の発症を予防する2020

    • Author(s)
      河内貴弘、中村庸輝、中島恵、劉克約、和氣秀徳、西堀正洋、入舩正浩、森岡徳光
    • Organizer
      第137回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] Histamine induced high mobility group box 1 release from vascular endothelial cells.2020

    • Author(s)
      Gao S, Wake H, Liu K, Wang D, Teshigawara K, Nishibori M.
    • Organizer
      第22回日本ヒスタミン学会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] 抗HMGB1抗体による硬膜下血腫の治療2020

    • Author(s)
      王登莉、高尚澤、劉克約、和氣秀徳、勅使川原 匡、森秀治、西堀正洋
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] Histidine-rich glycoprotein regulates neutrophil condition in sepsis.2020

    • Author(s)
      Wake H, Mori S, Takahashi H, Wang D, Teshigawara K, Nishibori M.
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] The effects of histidine-rich glycoprotein on neutrophil-like differentiated cell lines.2020

    • Author(s)
      Yoshii Y, Wake H, Teshigawara K, Wang D, Liu K, Takahashi Y, Nishibori M.
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] 抗HMGB1抗体による硬膜下血腫の治療2020

    • Author(s)
      王登莉, 高尚澤, 劉克約, 和氣秀徳, 勅使川原匡, 森秀治, 西堀正洋
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-20K07290
  • [Presentation] ラットの脳内出血および硬膜下出血に対する抗HMGB1抗体の治療効果2020

    • Author(s)
      王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] 好中球様細胞におけるHistidine-Rich Glycoprotein(HRG)の効果2020

    • Author(s)
      吉井 将哲、和氣 秀徳、勅使川原 匡、王 登莉、劉 克約、髙橋 陽平、西堀 正洋
    • Organizer
      日本薬理学会(横浜、新型コロナのため誌上開催、2020年3月16日-18日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 終末糖化産物結合因子の探索研究とAGEs-RAGE結合遮断領域の同定2020

    • Author(s)
      森 秀治、渡邊 政博、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、豊村 隆男
    • Organizer
      日本薬理学会(横浜、新型コロナのため誌上開催、2020年3月16日-18日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] Functional Evaluation of Neutrophils Spheroidized by HRG.2020

    • Author(s)
      Takahashi Y, Wake H, Teshigawara K, Wang D, Nishibori M.
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] 胎盤形成と妊娠期高血圧における血漿高ヒスチジン糖タンパクの生理的役割の解析2020

    • Author(s)
      勅使川原 匡、劉 克約、和氣 秀徳、王 登莉、森 秀治、髙橋 英夫、西堀 正洋
    • Organizer
      日本薬理学会(横浜、新型コロナのため誌上開催、2020年3月16日-18日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 高ヒスチジン糖タンパク質は敗血症病態下における好中球の状態を制御する2020

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、王 登莉、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会(横浜、新型コロナのため誌上開催、2020年3月16日-18日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 眼窩下神経慢性絞扼モデルマウスに対する神経傷害部位へのHMGB1中和抗体投与は三叉神経領域における疼痛様行動を抑制する2020

    • Author(s)
      河内貴弘、中村庸輝、中島一恵、劉克約、和氣秀徳、西堀正洋、入舩正浩、森岡徳光
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] HRGの作用により球状化した好中球の機能評価2020

    • Author(s)
      高橋 陽平、和氣 秀徳、勅使川原 匡、Wang Dengli、吉井 将哲、西堀 正洋
    • Organizer
      日本薬理学会(横浜、新型コロナのため誌上開催、2020年3月16日-18日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] ラットの脳内出血および硬膜下出血に対する抗HMGB1抗体の治療効果2020

    • Author(s)
      王 登莉、劉 克約、和氣 秀徳、勅使川原 匡、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会(横浜、新型コロナのため誌上開催、2020年3月16日-18日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] High mobility group box-1 は三叉神経障害に起因する痛覚異常の発症に寄与する2019

    • Author(s)
      中村庸輝、河内貴弘、中島一恵、劉克約、和氣秀徳、西堀正洋、入船正浩、森岡徳光
    • Organizer
      生体機能と創薬シンポジウム2019
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] Roles of innate immune molecules in repeated stress-induced neuronal and behavioral changes.2019

    • Author(s)
      Kitaoka S, Tomohiro A, Ukeshima S, Liu K, Wake H, Teshigawara K, Nishibori M, Furuyashiki T.
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] 終末糖化産物はラクトフェリンに結合し,ラクトフェリン誘導性TNF-α発現応答を抑制する2019

    • Author(s)
      森 秀治、渡邊 政博、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、豊村 隆男
    • Organizer
      日本薬理学会 (大阪、2019年3月14日-16日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019

    • Author(s)
      Shangze Gao, Hidenori Wake, Sakaguchi Masakiyo, Dengli Wang, Shuji Mori, Keyue Liu, Kiyoshi Teshigawara, Yuan Gao, Hideo Takahashi, Masahiro Nishibori.
    • Organizer
      9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧の病態解析2019

    • Author(s)
      勅使川原 匡、劉 克約、和氣 秀徳、王 登莉、髙橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会(大阪、2019年3月14日-16日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] AGEs結合因子の分子同定と炎症性サイトカイン発現応答への影響2019

    • Author(s)
      森 秀治、渡邊 政博、和氣 秀徳、勅使川原 匡、劉 克約、高橋 英夫、西堀 正洋、豊村 隆男
    • Organizer
      日本分子生物学会年会(福岡、2019年12月3-6日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats.2019

    • Author(s)
      Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] Roles and mechanisms of neuroinflammation in stress and depression.2019

    • Author(s)
      Furuyashiki T, Ukeshima S, Kitaoka S, Nie X, Liu K, Wake H, Teshigawara K, Nishibori M.
    • Organizer
      American College of Neuropsychopharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] HRGの作用により球状化したヒト好中球の貪食機能解析2019

    • Author(s)
      高橋陽平、和氣秀徳、吉井將哲、阪口政清、劉克約、勅使川原 匡、高橋英夫、森秀治、西堀正洋
    • Organizer
      日本薬理学会近畿部会(岐阜、2019年6月21日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] マウス反復社会挫折ストレスによる社会忌避行動の誘導におけるHMGB1の役割2019

    • Author(s)
      北岡志保、友廣彩夏、請島慎也、劉克約、和氣秀徳、勅使川原匡、西堀正洋、古屋敷智之
    • Organizer
      第135回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] 炎症誘発活性を有する新規AGEs結合分子の同定2019

    • Author(s)
      渡邊 政博、豊村 隆男、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、森 秀治
    • Organizer
      日本薬理学会近畿部会(岐阜、2019年6月21日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 好中球様細胞におけるHistidine-Rich Glycoprotein(HRG)の影響2019

    • Author(s)
      吉井 将哲、和氣 秀徳、高橋 陽平、王 登莉、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会近畿部会(岐阜、2019年6月21日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] インターアルファインヒビタータンパクは好中球形態を制御し、活性酸素分子種産生を抑制することによって好中球の静穏状態を維持する2019

    • Author(s)
      HTWE SOE SOE、和氣 秀徳、劉 克約、勅使川原 匡、Stonestreet Barbara S.、Lim Yow-Pin、西堀 正洋
    • Organizer
      日本薬理学会(大阪、2019年3月14日-16日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] マウス反復社会挫折ストレスによる社会忌避行動の誘導におけるHMGB1の役割2019

    • Author(s)
      北岡志保、友廣彩夏、請島慎也、劉克約、和氣秀徳、勅使川原 匡、西堀正洋、古屋敷智之
    • Organizer
      日本薬理学会近畿部会(岐阜、2019年6月21日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] HRGの作用により球状化したヒト好中球の貪食能解析2019

    • Author(s)
      高橋陽平, 和氣秀徳, 吉井將哲, 阪口政清, 劉克約, 勅使川原匡, 高橋英夫, 森秀治, 西堀正洋
    • Organizer
      第135回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧、及び、胎盤形成異常の解析2019

    • Author(s)
      勅使川原 匡、劉 克約、和氣 秀徳、王 登莉、髙橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本内分泌学会(仙台、2019年5月9日-11日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019

    • Author(s)
      Gao S, Wake H, Sakaguchi M, Wang D, Mori S, Liu K, Teshigawara K, Gao Y, Takahashi H, Nishibori M.
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] Perineural treatment with anti-HMGB1 antibody alleviates trigeminal neuropathy in mouse with chronic constriction injury of distal infraorbital nerve.2019

    • Author(s)
      Kochi T, Nakamura Y, Hisaoka-Nakashima K, Liu K, Wake H, Nishibori M, Irifune M, Morioka N.
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] 終末糖化産物による炎症応答と細胞増殖応答2019

    • Author(s)
      豊村 隆男、渡邊 政博、和氣 秀徳、勅使川原 匡、劉 克約、高橋 英夫、西堀 正洋、森 秀治
    • Organizer
      日本分子生物学会年会(福岡、2019年12月3-6日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] AGEs と炎症関連分子の共存が炎症反応に与える変化の検討2019

    • Author(s)
      渡邊 政博、豊村 隆男、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、森 秀治
    • Organizer
      日本薬理学会近畿部会(大阪、2019年11月23日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 周産期における高ヒスチジン糖タンパク(HRG)の生理的役割の解析2019

    • Author(s)
      勅使川原 匡、劉 克約、和氣 秀徳、王 登莉、髙橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会近畿部会(岐阜、2019年6月21日)
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] Roles of innate immune molecules in repeated stress-induced neuronal and behavioral changes.2019

    • Author(s)
      Shiho Kitaoka, Ayaka Tomohiro, Shinya Ukeshima, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Masahiro Nishibori, Tomoyuki Furuyashiki.
    • Organizer
      9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 好中球様細胞におけるHistidine-Rich Glycoprotein(HRG)の影響2019

    • Author(s)
      吉井将哲, 和氣秀徳, 高橋陽平, 王登莉, 勅使川原匡, 西堀正洋
    • Organizer
      第135回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] The role of HMGB1 in oral inflammation and regeneration.2019

    • Author(s)
      Yamashiro K, Ideguchi H, Aoyagi H, Yoshihara-Hirata C, Kawamura M, Yamasaki M, Kyoshima-Suzuki R, Yao Z, Hirai A, Wake H, Nishibori M, Yamamoto T, Takashiba A.
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019

    • Author(s)
      Gao S, Wake H, Sakaguchi M, Wang D, Mori S, Liu K, Teshigawara K, Gao Y, Takahashi H, Nishibori M.
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] Therapeutic time window of anti-high mobility group box-1 antibody administration in mouse model of spinal cord injury.2019

    • Author(s)
      Nakajo M, Uezono N, Nakashima H, Wake H, Nishibori M, Nakashima K, Tanagushi N.
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03408
  • [Presentation] Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats.2019

    • Author(s)
      Dengli Wang, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
    • Organizer
      9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] Advanced glycation end products interact with lactoferrin, and change the lactoferrin-stimulated proinflammatory cytokine response.2019

    • Author(s)
      Shuji Mori, Masahiro Watanabe, Hidenori Wake, Kiyoshi Teshigawara, Keyue Liu, Hideo Takahashi, Masahiro Nishibori, Takao Toyomura.
    • Organizer
      9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07401
  • [Presentation] 高ヒスチジン糖タンパク(histidine-rich glycoprotein)遺伝子欠損マウスの妊娠期表現型の解析2018

    • Author(s)
      勅使川原 匡、劉 克約、和氣 秀徳、王 登莉、髙橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会近畿部会(広島、2018年6月1日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Effects of inter-alpha inhibitor proteins (IAIP) on neutrophil functions.2018

    • Author(s)
      Htwe SS, Wake H, Liu K, Teshigawara K, Stonestreet BS, Lim YP.
    • Organizer
      第138回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Characterization of histidine-rich glycoprotein (HRG) production under the experimental pathological conditions.2018

    • Author(s)
      Kiyoshi Teshigawara, Atsuko Niwa, Hidenori Wake, Dengli Wang, Keyue Liu, Shuji Mori, Hideo Takahashi, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Pathophysiological role of a factor affecting AGEs-RAGE interaction on endothelial cell responses.2018

    • Author(s)
      Shuji Mori, Masahiro Watanabe, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Hideo Takahashi, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Anti-High Mobility Group Box-1 Antibody Therapy Might Prevent Cognitive Dysfunction After Traumatic Brain Injury.2018

    • Author(s)
      Yu Okuma, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Hideo K Takahashi, Nobuyuki Hirotsune, Shigeki Nishino, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Protective effect of histidine rich glycoprotein (HRG) on human vascular endothelial cells.2018

    • Author(s)
      Gao Y, Wake H, Liu K, Teshigawara K, NishiboriM.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 遺伝子改変細胞を用いたDAMPs分子の作用メカニズム解析2018

    • Author(s)
      渡邊 政博、豊村 隆男、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、森秀治
    • Organizer
      日本薬理学会近畿部会(広島、2018年6月1日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Anti-HMGB1 mAb therapy for intracerebral hemorrhage-induced brain injury in rats.2018

    • Author(s)
      Dengli Wang, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] The role of histidine-rich glycoprotein on immunothrombosis in septic organ failure.2018

    • Author(s)
      Hidenori Wake, Shuji Mori, Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Yuan Gao, Hideo K Takahashi, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧症候群様表現型の解析2018

    • Author(s)
      勅使川原 匡、劉 克約、兼森 玄、和氣 秀徳、王 登莉、髙橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会近畿部会(神戸、2018年11月23日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Protective Effects of Histidine-rich Glycoprotein on Barrier Dysfunction of Vascular Endothelial Cells.2018

    • Author(s)
      Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Protective effects of Histidine-rich glycoprotein on human vascular endothelial cells.2018

    • Author(s)
      Yuan Gao, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] The role of histidine-rich glycoprotein on immunothrombosis in septic organ failure.2018

    • Author(s)
      Wake H, Mori S, Teshigawara K, Liu K, Wang D, Gao Y, Takahashi HK, Nishibori M.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] 血漿タンパクHistidine-rich glycoprotein の多彩な作用とバイオ製剤の臨床応用2018

    • Author(s)
      和氣秀徳、西堀正洋
    • Organizer
      第92回日本薬理学会年会(シンポジウム)
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] The involvement of immunothrombosis in septic multiple organ failure.2018

    • Author(s)
      和氣 秀徳
    • Organizer
      第40回日本血栓止血学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] AGEs-TWEAK相互作用による炎症応答の制御2018

    • Author(s)
      森 秀治、渡邊 政博、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、豊村 隆男
    • Organizer
      日本生化学会(京都、2018年9月24-26日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] The role of histidine-rich glycoprotein on immunothrombosis in septic organ failure.2018

    • Author(s)
      Wake H, Mori S, Teshigawara K, Liu K, Wang D, Gao Y, Takahashi HK, Nishibori M.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Effects of inter-alpha inhibitor proteins (IAIP) on neutrophil functions.2018

    • Author(s)
      Htwe SS, Wake H, Liu K, Teshigawa K, Stonestreet BS, Lim YP, Nishibori M.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 新規敗血症治療薬及び診断マーカーHistidine-rich glycoproteinの開発2018

    • Author(s)
      和氣 秀徳、森 秀治、王 登莉、勅使川原 匡、西堀 正洋
    • Organizer
      日本生化学会(京都、2018年9月24-26日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Protective effects of histidine-rich glycoprotein on barrier dysfunction of vascular endothelial cells.2018

    • Author(s)
      Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] Effects of histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: implications for a role under septic conditions.2018

    • Author(s)
      Zhong H, Wake H, Liu K, Gao Y, Teshigawara K, Sakaguchi M, Mori S, Nishibori M.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] 炎症関連血管障害に関与するDAMP/anti-DAMP2018

    • Author(s)
      和氣 秀徳
    • Organizer
      CVMW2018心血管代謝週間
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] 高ヒスチジン糖タンパク(histidine-rich glycoprotein, HRG)と結合親和性をもつ炎症関連血漿タンパクの探索解析2018

    • Author(s)
      勅使川原 匡、丹羽 淳子、衷 輝、和氣 秀徳、劉 克約、王 登莉、高橋 英夫、森秀治、西堀正洋
    • Organizer
      日本生化学会(京都、2018年9月24-26日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Effects of Histidine-Rich Glycoprotein on Erythrocyte Aggregation and Hemolysis: Implications for a Role under Septic Conditions.2018

    • Author(s)
      Hui Zhong, Hidenori Wake, Keyue Liu, Yuan Gao, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Shuji Mori, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Protective Effects of Histidine-rich Glycoprotein on Barrier Dysfunction of Vascular Endothelial Cells.2018

    • Author(s)
      Shangze Gao, Yuan Gao, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Shiji Mori, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] The effects of histidine-rich glycoprotein on neutrophil-like differentiated cell lines.2018

    • Author(s)
      Yukinori Yoshii, Hidenori Wake, Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Yohei Takahashi, Masahiro Nishibori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] ダメージ関連分子HMGB1の糖代謝制御への関与の検討2018

    • Author(s)
      兼森 玄、勅使川原 匡、劉 克約、和氣 秀徳、王 登莉、高橋 英夫、森 秀治、西堀 正洋
    • Organizer
      西日本医学生学術フォーラム2018(三重、2018年12月15日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] 炎症惹起因子HMGB1の糖代謝制御に対する生理的役割の検討2018

    • Author(s)
      兼森 玄、勅使川原 匡、劉 克約、和氣 秀徳、王 登莉、高橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会近畿部会(神戸、2018年11月23日)
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice.2018

    • Author(s)
      Masahiro Nishibori, Li Fu, Hidenori Wake, Dengli Wang, Kiyoshi Teshigawara, Keyue Liu, Hideo K Takahashi, Shuji Mori.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology (WCP2018). (Japan, Kyoto,Jul 1-6/2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Protective effects of histidine-rich glycoprotein (HRG) on human vascular endothelial cells2017

    • Author(s)
      高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Histidine-rich glycoprotein (HRG)の好中球制御による敗血症治療薬の可能性2017

    • Author(s)
      和氣秀徳、高遠、森秀治、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第132回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 敗血症病態におけるNETsと免疫血栓形成に対する高ヒスチジン糖タンパク質の役割2017

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] 抗HMGB1抗体による脳内出血の治療2017

    • Author(s)
      王 登莉、劉 克約、和氣 秀徳、勅使川原 匡、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] The role of histidine-rich glycoprotein on NETosis and immunothrombosis in septic condition2017

    • Author(s)
      和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2017-03-17
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 赤血球のPSエクスプレション、吸着と疑集におけるHistidine rich-glycoprotein の調節機構2017

    • Author(s)
      衷 輝、和氣 秀徳、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] 抗HMGB1モノクローナル抗体によるピロカルピン誘導性癲癇マウスの病態改善効果の検討2017

    • Author(s)
      富 麗、劉 克約、和氣 秀徳、勅使川原 匡、高橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Protective effects of histidine-rich glycoprotein (HRG) on vascular endothelial cells2017

    • Author(s)
      高尚澤、和氣秀徳、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2017-03-16
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Protective effects of histidine-rich glycoprotein on barrier function of vascular endothelial cells.2017

    • Author(s)
      Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M.
    • Organizer
      第131回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] EFFECTS OF INTER-ALPHA INHIBITOR PROTEINS (IAIP) ON THE SHAPE AND REACTIVE OXYGEN SPECIES (ROS) PRODUCTION IN PURIFIED HUMAN NEUTROPHILS2017

    • Author(s)
      Soe Soe Htwe、Hidenori Wake、Keyue Liu、Kiyoshi Teshigawara、Yow Pin Lim、Masahiro Nishibori
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Histidine-rich glycoprotein protects vascular endothelial cells and red blood cells in sepsis.2017

    • Author(s)
      Wake H, Gao Y, Hui Z, Gao S, Mori S, Morimatsu H, Nishibori M.
    • Organizer
      Sepsis2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] EFFECTS OF INTER-ALPHA INHIBITOR PROTEINS (IAIP) ON THE SHAPE AND REACTIVE OXYGEN SPECIES (ROS) PRODUCTION IN PURIFIED HUMAN NEUTROPHILS2017

    • Author(s)
      Soe Soe Htwe, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Yow Pin Lim, Masahiro Nishibori
    • Organizer
      日本薬理学会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Protective effects of histidine-rich glycoprotein on barrier function of vascular endothelial cells.2017

    • Author(s)
      Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M.
    • Organizer
      第131回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] Histidine rich-glycoprotein regulates erythrocyte PS expression adherent and aggregation2017

    • Author(s)
      衷輝、和氣秀徳、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2017-03-16
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Histidine-rich glycoprotein (HRG)の好中球制御による敗血症治療薬の可能性2017

    • Author(s)
      和氣秀徳、高遠、森秀治、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第132回日本薬理学会近畿部会
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] Hitidine-Rich Glycoprotein as a Novel Prognostic Blomarker for Sepsis: Multicenter prospective observational study.2017

    • Author(s)
      Kuroda K, Morimatsu H, Kawanoue N, Wake H, Mori S, Nishibori M.
    • Organizer
      Sepsis2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 動脈硬化・血栓症とDAMP/anti-DAMP2017

    • Author(s)
      和氣 秀徳
    • Organizer
      第49回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K15580
  • [Presentation] Histidine-rich glycoprotein (HRG) の血管内皮細胞保護の効果2017

    • Author(s)
      高 尚澤、和氣 秀徳、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] ヒト血管内皮細胞におけるHistidine rich-glycoprotein (HRG) の保護効果2017

    • Author(s)
      高 遠、和氣 秀徳、劉 克約、勅使川原 匡、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-15
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] 敗血症性ARDSにおけるImmunothrombosis2016

    • Author(s)
      和氣 秀徳、西堀 正洋
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 破骨細胞分化過程に対して非炎症分子SHILsが及ぼす影響2016

    • Author(s)
      豊村 隆男、渡邉 政博、和氣 秀徳、勅使川原 匡、劉 克約、高橋 英夫、西堀 正洋、森 秀治
    • Organizer
      日本生化学会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] ヒト血管内皮細胞におけるHistidine rich glycoprotein(HRG)の保護効果2016

    • Author(s)
      高 遠、和氣 秀徳、劉 克約、勅使川原 匡、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] AGEs親和性因子としての60S ribosomal proteinの単離2016

    • Author(s)
      森 秀治、渡邊 政博、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、豊村 隆男
    • Organizer
      日本生化学会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] ピロカルピン誘導性てんかんモデルマウスにおける抗HMGB1抗体の炎症抑制効果2016

    • Author(s)
      富 麗、劉 克約、和氣 秀徳、勅使川原 匡、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 敗血症時好中球微小循環イメージング2016

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] ヒト血管内皮細胞におけるHistidine rich glycoprotein (HRG) の保護効果2016

    • Author(s)
      高 遠、和氣 秀徳、劉 克約、勅使川原 匡、森 秀治、西堀 正洋
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Endotoxemia併発急性膵炎に対するHistidine-rich gloycoprotein(HRG)の動態及び治療効果2016

    • Author(s)
      寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、高橋英夫、森秀治、西堀正洋
    • Organizer
      第129回日本薬理学会近畿部会
    • Place of Presentation
      広島県医師会館(広島県広島市)
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] AGEsによるTNF関連分子の機能変化2016

    • Author(s)
      渡邊 政博、豊村 隆男、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、森 秀治
    • Organizer
      日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Year and Date
      2016-11-19
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Histidine rich glycoproteinの敗血症時好中球性微小循環障害に対する影響2016

    • Author(s)
      和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第129回日本薬理学会近畿部会
    • Place of Presentation
      広島県医師会館(広島県広島市)
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 抗HMGB1抗体による脳内出血の治療2016

    • Author(s)
      王 登莉、劉 克約、和氣 秀徳、勅使川原 匡、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] Anti-HMGB1 mAb attenuates cerebral vasospasm and brain injury after subarachnoid hemorrhage in rats.2016

    • Author(s)
      勅使川原 匡、春間 純、菱川 朋人、王 登莉、劉 克約、和氣 秀徳、森 秀治、髙橋 英夫、杉生 憲志、伊達 勲、西堀 正洋
    • Organizer
      日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Year and Date
      2016-11-19
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] 敗血症時好中球微小循環イメージング2016

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 敗血症性ARDSにおけるimmunothrombus形成に対する高ヒスチジン糖タンパク質の役割2016

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本生化学会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Damps関連サイトカインの機能に対するAGEsの影響2016

    • Author(s)
      渡邊 政博、豊村 隆男、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、森 秀治
    • Organizer
      日本生化学会
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] 70kD AGEs結合因子によるAGEsシグナリングへの影響2016

    • Author(s)
      森 秀治、渡邊 政博、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、豊村 隆男
    • Organizer
      日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] Protective effects of histidine rich glycoprotein (HRG) on human vascular endothelial cells2016

    • Author(s)
      高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
    • Organizer
      第129回日本薬理学会近畿部会
    • Place of Presentation
      広島県医師会館(広島県広島市)
    • Year and Date
      2016-06-24
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 敗血症性ARDSにおけるimmunothrombus形成に対する高ヒスチジン糖タンパク質の役割2016

    • Author(s)
      和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] ストレプトゾトシン誘発糖尿病ラットにおけるAdvanced glycation end-productsの検出2016

    • Author(s)
      森岡 祐太、和氣 秀徳、勅使川原 匡、劉 克約、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 非炎症分子SHILsはサイトカインとともに破骨細胞分化を調節する2016

    • Author(s)
      豊村 隆男、渡邊 政博、和氣 秀徳、勅使川原 匡、劉 克約、高橋 英夫、西堀 正洋、森 秀治
    • Organizer
      日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K08232
  • [Presentation] The effects of anti-HMGB1 antibody on pilocarpine-induced epilepsy in mice.2015

    • Author(s)
      Fu L, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
    • Organizer
      7th International Symposium DAMPS and HMGB1.
    • Place of Presentation
      Germany, Bonn, University Hospital Bonn.
    • Year and Date
      2015-09-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 高ヒスチジン糖タンパク質(HRG)の敗血症性immunothrombosis形成に対する影響2015

    • Author(s)
      和氣 秀徳、森 秀治、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      第128回日本薬理学会近畿部会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2015-11-20
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 敗血症病態における微小循環障害に対する高ヒスチジン糖タンパク質の役割2015

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] 敗血症病態における高ヒスチジン糖タンパク質(HRG)の好中球形態と微小循環に対する影響2015

    • Author(s)
      和氣 秀徳、森 秀治、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会近畿部会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] Tissue factor ( TF ) 誘発DICモデルにおけるHistidine-rich glycoprotein ( HRG ) の動態及び治療効果について2015

    • Author(s)
      寺尾 欣也、和氣 秀徳、森岡 祐太、勅使川原 匡、劉 克約、高橋 英夫、森 秀治、西堀 正洋
    • Organizer
      第127回日本薬理学会近畿部会
    • Place of Presentation
      長良川国際会議場(岐阜県岐阜市)
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Tissue factor ( TF ) 誘発DICモデルにおけるHistidine-rich glycoprotein ( HRG ) の動態及び治療効果について2015

    • Author(s)
      寺尾 欣也、和氣 秀徳、森岡 祐太、勅使川原 匡、劉 克約、髙橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会近畿部会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 敗血症病態における高ヒスチジン糖タンパク質(HRG)の好中球形態と微小循環に対する影響2015

    • Author(s)
      和氣 秀徳、森 秀治、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      第127回日本薬理学会近畿部会
    • Place of Presentation
      長良川国際会議場(岐阜県岐阜市)
    • Year and Date
      2015-06-26
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Histidine-Rich Glycoprotein as a Novel Prognostic Biomarker in Critically Ill Patients.2015

    • Author(s)
      Kuroda K, Morimatsu H, Wake H, Mori S, Nishibori M.
    • Organizer
      Euroanaesthesia 2015 (Annual meeting of European Society of Anesthesiology)
    • Place of Presentation
      Berlin(Germany)
    • Year and Date
      2015-05-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Anti-HMGB1 therapy for intracerebral hemorrhage.2015

    • Author(s)
      Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
    • Organizer
      7th International Symposium DAMPS and HMGB1.
    • Place of Presentation
      Germany, Bonn, University Hospital Bonn.
    • Year and Date
      2015-09-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] SIRSにおける新たな重症度バイオマーカーとしてのHistidine-Rich Glycoprotein:前向き観察研究2015

    • Author(s)
      黒田 浩佐、森松 博史、和氣 秀徳、森 秀治、西堀 正洋
    • Organizer
      日本麻酔科学会 第62回学術集会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県神戸市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-15H04686
  • [Presentation] Receptor for advanced glycation end product と肺障害2014

    • Author(s)
      出石 恭久、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] AGEs結合親和性に基づいたAGEs遮断ペプチドの同定2014

    • Author(s)
      横山隆太、豊村隆男、和氣秀徳、勅使川原匡、劉克約、高橋英夫、西堀正洋、森秀治
    • Organizer
      第125回日本薬理学会近畿部会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Year and Date
      2014-06-20
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] コラゲナーゼ誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014

    • Author(s)
      劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] Endotoxin血症併発急性膵炎に対するHistidine Rich Grycoprotein(HRG)の効果2014

    • Author(s)
      寺尾 欣也、和氣 秀徳、森岡 祐太、勅使川原 匡、劉 克約、森 秀治、高橋 英夫、西堀 正洋
    • Organizer
      日本薬理学会 近畿部会
    • Place of Presentation
      岡山
    • Year and Date
      2014-06-20
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014

    • Author(s)
      劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター(仙台)
    • Year and Date
      2014-03-20
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014

    • Author(s)
      劉 克約、王 登利、和氣 秀徳、勅使川原 匡、高橋 英夫、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 高ヒスチジン糖タンパク(HRG)による敗血症治療の可能性2014

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 炎症誘発因子HMGB1とインスリン抵抗性の関係についての検討2014

    • Author(s)
      衷 輝、勅使川原 匡、和氣 秀徳、劉 克約、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 高ヒスチジン糖タンパク質の好中球走化性に対する影響2013

    • Author(s)
      和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody.2013

    • Author(s)
      Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S.
    • Organizer
      Signalling in the Blood-Brain Barriers.
    • Place of Presentation
      Hotel Kapitany, Sumeg, Hungary.
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013

    • Author(s)
      Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S
    • Organizer
      Merinoff World Congress 2013:HMGB1
    • Place of Presentation
      Feinstein Institute for Medical Research, New York, USA
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013

    • Author(s)
      Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S
    • Organizer
      Signalling in the Blood-Brain Barriers
    • Place of Presentation
      Hotel Kapitány,Sümeg, Hungary
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] Glycyrrhizin therapy for traumatic brain injury.2013

    • Author(s)
      Okuma Y, Liu K, Wake H, Teshigawara K, Haruma J, Date I, Nishibori M.
    • Organizer
      Shanghai BRAIN 2013.
    • Place of Presentation
      Shanghai International Convention Center, Shanghai, China.
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013

    • Author(s)
      Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S
    • Organizer
      Signalling in the Blood-Brain Barriers
    • Place of Presentation
      Hotel Kapitany, Sumeg, Hungary
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013

    • Author(s)
      Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S
    • Organizer
      Merinoff World Congress 2013 : HMGB1
    • Place of Presentation
      Feinstein Institute for Medical Research, New York, USA
    • Year and Date
      2013-10-09
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] ピルカルピンで誘発癲癇モデルにおける抗HMGB1単クローン抗体の効果2013

    • Author(s)
      劉克約、富麗、和氣秀徳、勅使川原匡、西堀正洋
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] ラットリンパ節細胞を用いた抗AGEモノクローナル抗体の作製2012

    • Author(s)
      森岡祐太,友野靖子,和氣秀徳,劉克約,勅使川原匡,高橋英夫,森秀治,西堀正洋
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] 虚血時脳神経細胞内HMGB1は、核からペルオキシソーム/ミトコンドリアに移動する2012

    • Author(s)
      福安悠介,劉克約,和氣秀徳,西村義人,勅使川原匡,西堀正洋
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] Anti-high mobility group box-1 antibody therapy for traumatic brain injury2012

    • Author(s)
      Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Tomura S, Otani N, Shima K, Yamamoto Y, Yamamoto H, Takahashi H, Mori S, Date I, Nishibori M
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans Morial Convention Center, New Orleans, USA
    • Year and Date
      2012-10-16
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2012

    • Author(s)
      和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2012-03-15
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] マクロファージによるAdvanced glycation end product (AGE)の細胞内取り込み2012

    • Author(s)
      (13)周京秀,渋谷恵,和氣秀徳,劉克約,森岡祐太,岡村舞,森秀治,西堀正洋
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2012

    • Author(s)
      和氣秀徳,森秀治,高橋英夫,劉克約,勅使川原匡,西堀正洋
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] 虚血時のBBB透過性亢進を濾出したEvans blue/Albuminの追跡検討2012

    • Author(s)
      劉克約,張継勇,和氣秀徳,勅使川原匡,高橋英夫,森秀治,西堀正洋
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] 頭部外傷モデルを用いた抗HMDB1抗体の神経保護効果の検討2012

    • Author(s)
      大熊佑、劉克約、和氣秀徳、勅使川原匡、高橋英夫、森秀治、伊達勲、西堀正洋
    • Organizer
      第121回日本薬理学会近畿部会
    • Place of Presentation
      あわぎんホール(徳島)
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2011

    • Author(s)
      和氣秀徳、森秀治、劉克約、高橋英夫、西堀正洋
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] HRGのHMGB1-ヘパリン複合体誘導性血管新生調節機構2011

    • Author(s)
      和氣秀徳、森秀治、高橋英夫、西堀正洋
    • Organizer
      第120回日本薬理学会近畿部会
    • Place of Presentation
      ホテルグランヴィア京都(京都)
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] Early translocation and release of HMGB1 in ischemic brain in rats2011

    • Author(s)
      劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-03-22
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Presentation] 抗HMGB1単クローン抗体はラット脳虚血による血液-脳関門の破錠を制御する2011

    • Author(s)
      西堀正洋, 張継勇, 劉克約,和氣秀徳, 高橋英夫, 森秀治,大塚愛二
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2011

    • Author(s)
      和氣秀徳, 森秀治, 劉克約,高橋英夫, 西堀正洋
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] HRGのHMGB1-ヘパリン複合体誘導性血管新生調節機構2011

    • Author(s)
      和氣秀徳, 森秀治, 高橋英夫, 西堀正洋
    • Organizer
      第120回日本薬理学会近畿部会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] 抗HMGB1抗体は脳虚血誘発性の血液-脳関門破綻を防ぐ2011

    • Author(s)
      劉克約,張 継勇, 和氣秀徳, 大塚愛二,森 秀治, 高橋英夫,西堀正洋
    • Organizer
      第119回日本薬理学会近畿部会
    • Place of Presentation
      愛知
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] .HMGB1単クローン抗体によるラットMCAO誘発脳梗塞の治療2011

    • Author(s)
      西堀正洋、劉克約、張継勇, 和氣秀徳, 大塚愛二,吉野正,伊達勲,高橋英夫, 森秀治
    • Organizer
      第47回高血圧関連疾患モデル学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23659687
  • [Presentation] 脳虚血早期におけるHMGB1の動態2010

    • Author(s)
      劉克約, 張継勇, 和氣秀徳, 高橋英夫, 森秀治, 西堀正洋
    • Organizer
      第118回日本薬理学会近畿部会
    • Place of Presentation
      千里ライフサイエンスセンター
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Presentation] Histamine inhibits advanced glycation end product-induced adhesion molecule expression on monocytes during human mixed lymphocyte reaction.2010

    • Author(s)
      張継勇, 高橋英夫, 劉克約, 和氣秀徳, 劉瑞, 森秀治, 西堀正洋
    • Organizer
      第117回日本薬理学会近畿部会
    • Place of Presentation
      徳島県郷土文化会館
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Presentation] 移植術後糖尿病に対するヒスタミンの効果の基礎検討2010

    • Author(s)
      高橋英夫, 劉克約, 和氣秀徳, 森秀治, 西堀正洋
    • Organizer
      第14回日本ヒスタミン学会
    • Place of Presentation
      川崎グランドホテル
    • Year and Date
      2010-10-24
    • Data Source
      KAKENHI-PROJECT-21390071
  • [Presentation] ラットリンパ節法によるALE特異モノクローナル抗体の作製

    • Author(s)
      森岡祐太、大西香織、友野靖子、森秀治、和氣秀徳、劉克約、勅使川原匡、西堀正洋
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] Histidine-rich glycoprotein prevents septic lethality through neutrophil regulation.

    • Author(s)
      Masahiro Nishibori, Hidenori Wake, Shuji Mori, Keyue Liu, Yuta Morioka, Kiyoshi Teshigawara, Masakiyo Sakaguchi, Kosuke Kuroda, Hideo Takahashi, Aiji Ohtsuka, Tadashi Yoshino, Hiroshi Morimatsu
    • Organizer
      Sepsis Symposium
    • Place of Presentation
      France, Paris, Pasteur Institute
    • Year and Date
      2014-12-03 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 破骨細胞様細胞の分化培養における非炎症性物質の影響

    • Author(s)
      豊村 隆男、和氣 秀徳、勅使川原 匡、劉 克約、高橋 英夫、西堀 正洋、森 秀治
    • Organizer
      日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] 好中球活性化制御に着目した敗血症病態解析と治療法開発

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] ピロカルピン誘発性てんかんモデルマウスにおける抗HMGB-1抗体の効果

    • Author(s)
      富麗、劉克約、和氣秀徳、西堀正洋
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] HRGのHMGB1-ヘパリン複合体誘導性血管新生調節機構

    • Author(s)
      和氣秀徳
    • Organizer
      第120回日本薬理学会近畿部会
    • Place of Presentation
      ホテルグランヴィア京都
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] グリチルリチンはHMGB1に結合し脳外傷を抑制する

    • Author(s)
      春間純、大熊佑、劉克約、和氣秀徳、衷輝、勅使川原匡、伊達勲、西堀正洋
    • Organizer
      第123回日本薬理学会近畿部会
    • Place of Presentation
      ウインク愛知
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] 高ヒスチジン糖タンパク質(HRG)の敗血症時血管内好中球流動性に対する効果

    • Author(s)
      和氣 秀徳、森 秀治、高橋 英夫、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats.

    • Author(s)
      Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S.
    • Organizer
      Merinoff World Congress 2013:HMGB1
    • Place of Presentation
      Feinstein Institute for Medical Research, New York, USA.
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] 高ヒスチジン糖タンパク質の好中球走化性に対する影響

    • Author(s)
      和氣秀徳
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析

    • Author(s)
      森秀治、和氣秀徳、劉克約、勅使川原匡、高橋英夫、西堀正洋、豊村隆男
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果

    • Author(s)
      劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
    • Organizer
      第87回日本薬理学会年会
    • Place of Presentation
      仙台国際センター
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する

    • Author(s)
      和氣秀徳
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-23790601
  • [Presentation] マクロファージによるAdvanced glycation end productsの細胞内取り込み

    • Author(s)
      森岡 祐太、周 京秀、渋谷 恵、和氣 秀徳、劉 克約、勅使川原 匡、森 秀治、西堀 正洋
    • Organizer
      日本薬理学会 近畿部会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] グリチルリチンはHMGB1に結合し脳外傷を抑制する

    • Author(s)
      春間 純、大熊 佑、劉 克約、和氣 秀徳、衷 輝、勅使川原 匡、伊達 勲、西堀 正洋
    • Organizer
      日本薬理学会 近畿部会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] ラットリンパ節法によるALE特異モノクローナル抗体の作製

    • Author(s)
      森岡 祐太、大西 香織、友野 靖子、森 秀治、和氣 秀徳、劉 克約、勅使川原 匡、西堀 正洋
    • Organizer
      日本薬理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析

    • Author(s)
      森 秀治、和氣 秀徳、劉 克約、勅使川原 匡、高橋 英夫、西堀 正洋、豊村 隆男
    • Organizer
      日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25460649
  • [Presentation] マクロファージによるadvanced glycation end products (AGEs)の細胞内取り込み

    • Author(s)
      高遠、森岡祐太、森秀治、和氣秀徳、劉克約、西堀正洋
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-24390061
  • [Presentation] Histidine-rich glycoprotein inhibited high mobility group box 1 in complex with heparin induced angiogenesis in matrigel plug assay

    • Author(s)
      和氣秀徳
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-23790601
  • 1.  NISHIBORI Masahiro (50135943)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 210 results
  • 2.  TAKAHASHI Hideo (60335627)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 111 results
  • 3.  RYU Katsuyaku (40432637)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 172 results
  • 4.  TESHIGAWARA Kiyoshi (40403737)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 136 results
  • 5.  Hatipoglu Omer Faruk (90791765)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 26 results
  • 6.  西中 崇 (50786184)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 28 results
  • 7.  王 登莉 (40815693)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 31 results
  • 8.  MORI Shuji (50220009)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 35 results
  • 9.  西田 圭一郎 (80284058)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  廣畑 聡 (90332791)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 11.  DATE Isao (70236785)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 12.  TERADA SEISHI (20332794)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YAMASHIRO KEISUKE (30581087)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  AOYAGI Hiroaki (10814501)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  IDEGUCHI Hidetaka (80779421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  KOCHI Shinsuke (70803138)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  YAMAMOTO Tadashi (50432662)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKASHIBA Shogo (50226768)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  白井 敦 (20302226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  丹羽 淳子 (60122082)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 21.  阪口 政清 (70379840)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 22.  逢坂 大樹 (70839141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  OKUMA Yu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  SADAMORI Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 25.  HISAOKA Kazue
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  WATANABE Shogo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  MATSUNAMI Maho
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  小堀 宅郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  豊村 隆男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  渡邊 政博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 31.  中村 庸輝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 32.  森岡 徳光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  稲垣 純子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi