MA GUANGYU 馬光宇

Researcher Number	60572162
Affiliation (based on the past Project Information) *help	2011: 東京大学, 医科学研究所, 助教
Review Section/Research Field	Except Principal Investigator Laboratory animal science
Keywords	Except Principal Investigator 間接リウマチ / 関節リウマチ / Th17細胞 / 自己免疫疾患 / 疾患モデル動物 / サイトカイン

Establishment of an IL-1-related gene-manipulated mice library, aiming at uncovering pathophysiology of disease from a view point of systems biology
- Principal Investigator
  
  IWAKURA Yoichiro
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  The University of Tokyo

All 2012 2011 2010 2009 2008

All Journal Article Presentation Patent

[Journal Article] Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier2012
- Author(s)
  有馬康伸
- Journal Title
  
  Cell
  
  Volume: 148(3) Issue: 3 Pages: 447-457
- DOI
  10.1016/j.cell.2012.01.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J05573, KAKENHI-PROJECT-11J00819, KAKENHI-PROJECT-20220009, KAKENHI-PUBLICLY-22021029
[Journal Article] Involvement of Interleukin-1 in Lead Nitrate-Induced Hypercholesterolemia in Mice2012
- Author(s)
  M.Kojima
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 2 Pages: 246-250
- DOI
  10.1248/bpb.35.246
- NAID
  130001872300
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-22590166
[Journal Article] Memory/effector(CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology2011
- Author(s)
  Kamanaka, M., Huber, S., Zenewicz, L. A., Gagliani, N., Rathinam, C., O' Connor, W. Jr., Wan, Y. Y., Nakae, S., Iwakura, Y., Hao, L., and Flavell, R. A.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 208 Pages: 1027-1040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Desmoglein 3-specific CD4+T cells induce pemphigus vulgaris and interface dermatitis in mice2011
- Author(s)
  Takahashi, H., Kouno, M., Nagao, K., Wada, N., Hata, T., Nishimoto, S., Iwakura, Y., Yoshimura, A., Yamada, T., Kuwana, M., Fujii, H., Koyasu, S., and Amagai, M.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 121 Pages: 3677-3688
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Muramyldipeptide augments the actions of lipopolysacchairde in mice by stimulating macrophages to produe pro-IL-1B and by down-regulation of suppressor of cytokine signaling 1(SOCS1)2011
- Author(s)
  Shikama, Y., Kuroishi, T., Nagai, Y., Iwakura, Y., Shimauchi, H., Takada, H., Sugawara, S., and Endo, Y.
- Journal Title
  
  Innate Immun.
  
  Volume: 17 Pages: 54-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin-1 Controls the Constitutive Expression of the Cyp7a1 Gene by Regulating the Expression of Cyp7a1 Transcriptional Regulators in the Mouse Liver2011
- Author(s)
  M.Kojima
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 34 Issue: 10 Pages: 1644-1647
- DOI
  10.1248/bpb.34.1644
- NAID
  130001086603
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-22590166
[Journal Article] Local microbleeding facilitates IL-6-and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells2011
- Author(s)
  Murakami, M., Okuyama, Y., Ogura, H., Asano, S., Arima, Y., Tsuruoka, M., Harada, M., Kanamoto, M., Sawa, Y., Iwakura, Y., Takatsu, K., Kamimura, D., and Hirano, T.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 208 Pages: 103-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice2011
- Author(s)
  M.S.Madhur
- Journal Title
  
  Arterioscler Thromb Vase Biol
  
  Volume: 31 Issue: 7 Pages: 1565-1572
- DOI
  10.1161/atvbaha.111.227629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Natural Killer T Cell-Derived IL-17Mediates Lung Ischemia-Reperfusion Injury2011
- Author(s)
  Sharma, A K
- Journal Title
  
  Am.J.Respir.Crit.Care Med.
  
  Volume: (in press)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Control of T(H) 17 cells occurs in the small intestine2011
- Author(s)
  Esplugues, E., Huber, S., Gagliani, N., Hauser, A. E., Town, T., Wan, Y. Y., O' Connor, W., Rongvaux, A., Van Rooijen, N., Haberman, A. M., Iwakura, Y., Kuchroo, V. K., Kolls, J. K., Bluestone, J. A., Herold, K. C., and Flavell, R. A.
- Journal Title
  
  Nature
  
  Volume: 475 Pages: 514-518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Protective role of naturally occurring interleukin-17A-producing Yδ T cells in the lung at the early stage of systemic candidiasis in mice2011
- Author(s)
  T.Dejima
- Journal Title
  
  Infect Immun
  
  Volume: 79 Issue: 11 Pages: 4503-4510
- DOI
  10.1128/iai.05799-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PUBLICLY-22021032, KAKENHI-PROJECT-22790468
[Journal Article] Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology2011
- Author(s)
  M.Kamanaka
- Journal Title
  
  J Exp Med
  
  Volume: 208 Issue: 5 Pages: 1027-1040
- DOI
  10.1084/jem.20102149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PROJECT-21390303
[Journal Article] NYAP : a phosphoprotein family that links PI3K to WAVE1 signalling in neurons2011
- Author(s)
  K.Yokoyama
- Journal Title
  
  EMBO J
  
  Volume: 30 Issue: 23 Pages: 4739-4754
- DOI
  10.1038/emboj.2011.348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009, KAKENHI-PLANNED-21115006, KAKENHI-PROJECT-21229006, KAKENHI-PROJECT-21680033, KAKENHI-PROJECT-22700391, KAKENHI-PROJECT-22700448, KAKENHI-PUBLICLY-23114504
[Journal Article] Muramyldipeptide augments the actions of lipopolysacchairde in mice by stimulating macrophages to produe pro-IL-1B and by down-regulation of suppressor of cytokine signaling 1 (SOCS1).2010
- Author(s)
  Shikama, Y.
- Journal Title
  
  Innate Immun. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] TNF but not IL-6 and IL17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Ill rn-/-mice.2010
- Author(s)
  Nakajima, A.
- Journal Title
  
  J.Immunol.
  
  Volume: 185 Pages: 1887-1893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung2010
- Author(s)
  Okamoto Yoshida, Y., Umemura, M., Yahagi, A., O' Brien, R. L., Ikuta, K., Kishihara, K., Hara, H., Nakae, S., Iwakura, Y., and Matsuzaki, G.
- Journal Title
  
  J. Immunol.
  
  Volume: 184 Pages: 4414-4422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Functional hypothalamic amenorrhea due to increased CRH tone in melanocortin receptor 2-deficient mice.2010
- Author(s)
  Matsuwaki, T.
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 5489-5496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] M. Type I interferon signaling constrains IL-17A/F secretion byγδT cells during bacterial infection2010
- Author(s)
  Henry, T., Kirimanjeswara, G. S., Ruby, T., Jones, J. W., Peng, K., Perret, M., Ho, L., Sauer, J.-D., Iwakura, Y., Metzger, D. W., and Monack, D.
- Journal Title
  
  J. Immunol.
  
  Volume: 184 Pages: 3755-3767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infection2010
- Author(s)
  Miyazaki, Y., Hamano, S., Wang, S., Shimanoe, Y., Iwakura, Y., and Yoshida, H.
- Journal Title
  
  J. Immunol.
  
  Volume: 185 Pages: 1150-1157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn^<-/-> mice2010
- Author(s)
  Nakajima, A., Matsuki, T., Komine, M., Asahina, A., Horai, R., Nakae, S., Ishigame, H., Kakuta, S., Saijo, S., and Iwakura, Y.
- Journal Title
  
  J. Immunol.
  
  Volume: 185 Pages: 1887-1893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Dectin-2 recognition ofα-mannans and induction of Th17 differentiation is essential for host defense against Candida albicans2010
- Author(s)
  Saijo, S., Ikeda, S., Yamabe, K., Kakuta, S., Ishigame, H., Akitsu, A., Fujikado, N., Kusaka, T., Kubo, S., Chung, S., Komatsu, R., Miura, N., Adachi, Y., Ohno, N., Shibuya, K., Yamamoto, N., Kawakami, K., Yamasaki, S., Saito, T., Akira, S., and Iwakura,
- Journal Title
  
  Immunity
  
  Volume: 32 Pages: 681-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-1 plays an important role in the bone metabolism under physiological conditions2010
- Author(s)
  Lee, Y.-M., Fujikado, N., Manaka, H., Yasuda, H., and Iwakura, Y.
- Journal Title
  
  Int. Immunol.
  
  Volume: 22 Pages: 805-816
- NAID
  10027907526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] E. Pulmonary inflammation triggered by Ricin toxin requires macrophages and IL-1 signaling2009
- Author(s)
  Lindauer, M. L., Wong, J., Iwakura, Y., and Magun, B.
- Journal Title
  
  J. Immunol.
  
  Volume: 183 Pages: 1419-1426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responsesfor the development of experimental autoimmune encephalo myelitis.2009
- Author(s)
  Oyamada, A.
- Journal Title
  
  J.Immunol. 183
  
  Pages: 7539-7546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] MHC-matched corneal allograft rejection in an IFN-γ/IL-17-independent manner in C57BL/6 mice.2009
- Author(s)
  Yamada, J.
- Journal Title
  
  Invest.Ophthalmol. Vis.Sci. 50
  
  Pages: 2139-2146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Differential roles of IL-17A and IL-17F in host defense against mucoepithelial bacterial infection and allergic responses2009
- Author(s)
  Ishigame, H., Kakuta, S., Nagai, T., Nambu, A., Komiyama, Y., Kadoki, M., Tanahashi, Y., Akitsu, A., Kotaki, H., Sudo, K., Nakae, S., Sasakawa, C., and Iwakura, Y
- Journal Title
  
  Immunity
  
  Volume: 30 Pages: 108-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Dok-7 activates the muscle receptor kinase MuSK and shapes synapse formation2009
- Author(s)
  Inoue, A., Setoguchi, K., Matsubara, Y., Okada, K., Sato, N., Iwakura, Y., Higuchi, O., and Yamanashi, Y.
- Journal Title
  
  Science Signaling
  
  Volume: 2 Pages: 7-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] A. A protective function for interleukin 17A in T cell-mediated intestinal inflammation2009
- Author(s)
  O' Connor, W. Jr., Kamanaka, M., Booth, C. J., Town, T., Nakae, S., Iwakura, Y., Kolls, J. K., and Flavell, R.
- Journal Title
  
  Nat. Immunol.
  
  Volume: 10 Pages: 603-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Therapeutic effects of interleukin-6 blockade in a murine model of polymyositis that does not require interleukin-17A.2009
- Author(s)
  Okiyama, N.
- Journal Title
  
  Arth.Rheum. 60
  
  Pages: 2505-2512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-1 regulates the Cyp7al gene and serum total cholesterol level at steady state in mice.2009
- Author(s)
  Kojima, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun., 279
  
  Pages: 239-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Pivotal role of cerebral interleukin-17-producingγδT cells in the delayed phase of ischemic brain injury2009
- Author(s)
  Shichita, T., Sugiyama, Y., Ooboshi, H., Sugimori, H., Nakagawa, R., Takada, I., Iwaki, T., Okada, Y., Iida, M., Cua, D. J., Iwakura, Y., and Yoshimura, A.
- Journal Title
  
  Nat. Med.
  
  Volume: 15 Pages: 946-950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction.2009
- Author(s)
  Madhur, M.S.
- Journal Title
  
  Hypertension 55
  
  Pages: 500-507
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin(IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-172009
- Author(s)
  Munoz, M., Heimesaat, M. M., Danker, K., Struck, D., Lohmann, U., Plickert, R., Bereswill, S., Fischer, A., Dunay, I. R., Wolk, K., Loddenkemper, C., Krell, H.-W., Libert, C., Lund, L. R., Frey, O., Holscher, C., Iwakura, Y., Ghilardi, N., Ouyang, W., Kamradt, T., Sabat, R., and Liesenfeld, O.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 206 Pages: 3047-3059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Deficiency of Tumor Necrosis Factor-α and Interferon-γ in Bone Marrow Cells Synergistically Inhibits Neointimal Formation Following Vascular Injury.2008
- Author(s)
  Muryama, H.
- Journal Title
  
  Cardiovasc. Res., 80
  
  Pages: 175-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of Natural Killer T cells and IL-172008
- Author(s)
  Pichavant, M., Goya, S., Meyer, E. H., Johnston, R. A., Kim, H. Y., Matangkasombut, P., Zhu, M., Iwakura, Y., Savage, P. B., DeKruyff, R. H., Shore, S. A., and Umetsu, D. T.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 205 Pages: 385-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Endogenous IL-17 Does Not Play a Significant Role in the Development of Experimental Murine Allergic Conjunctivitis.2008
- Author(s)
  Fukushima, A.
- Journal Title
  
  Int. Arch. Allergy Immjnol., 147
  
  Pages: 206-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-17A Produced by γδT Cells Plays a Critical Role in Immunity against Listeria monocytogenes Infection in the Liver.2008
- Author(s)
  Hamada, S.
- Journal Title
  
  J. Immunol., 181
  
  Pages: 3456-3463
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8^+T cells.2008
- Author(s)
  Tajima, M.
- Journal Title
  
  J. Exp. Med., 205
  
  Pages: 1019-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Either a Th17 or a Th1 effector response can drive autoimmunity : conditions of disease induction affect dominant effector category2008
- Author(s)
  Luger, D., Silver, P. B., Tang, J., Cua, D., Chen, Z., Iwakura, Y., Bowman, E. P., Sgambellone, N. M., Chan, C.-C. and Caspi, R.
- Journal Title
  
  J. Exp. Med.
  
  Volume: 205 Pages: 799-810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] The role of DCIR in the development of autoimmune diseases2008
- Author(s)
  Fujikado, N., Saijo, S., Yonezawa, T., Shimamori, K., Ishii, A., Sugai, S., Kotaki, H., Sudo, K., Nose, M., and Iwakura, Y.
- Journal Title
  
  Cytokine
  
  Volume: 43 Pages: 244-244
- NAID
  40017145116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis2008
- Author(s)
  Izcue, A., Hue, S., Buonocore, S., Arancibia-Carcamo, C. V., Ahern, P. P., Iwakura, Y., Maloy, K. J., and Powrie, F
- Journal Title
  
  Immunity
  
  Volume: 28 Pages: 559-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] K. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia2008
- Author(s)
  Aujla, S. J., Fei, M., Pociask, D. A., Reinhart, T. A., Edeal, J., Gaus, K., Kreindler, J. L., Dubin, P. J., Zheng, M., Pilewski, J. M., Myerburg, M. M., Mason, C. A., Iwakura, Y., and Kolls, J.
- Journal Title
  
  Nature Med.
  
  Volume: 14 Pages: 275-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] L-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8^+T cells2008
- Author(s)
  Tajima, M., Wakita, D., Noguchi, D., Chamoto, K., Yue, Z, Fugo, K., Ishigame, H., Iwakura, Y., Kitamura, H., and Nishimura, T
- Journal Title
  
  J. Exp. Med.
  
  Volume: 205 Pages: 1019-1027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction2008
- Author(s)
  Ogura, H., Murakami, M., Okyuyama, Y., Tsuruoka, M., Kitabayashi, C., Kanamoto, M., Nishihara, M., Iwakura, Y., and Hirano, T.
- Journal Title
  
  Immunity
  
  Volume: 29 Pages: 628-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Journal Article] Contribution of IL-1 to resistance to Streptococcus pneumoniae infection2008
- Author(s)
  Kafka, D., Ling, E., Feldman, G., Benharroch, D., Voronov, E., Givon-Laci, N., Iwakura, Y., Dagan, R., Apte, R. N., and Mizrachi-Nebenzahi, Y.
- Journal Title
  
  Int. Immunol.
  
  Volume: 9 Pages: 1139-1146
- NAID
  10022599302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20220009
[Patent] 樹状細胞免疫受容体刺激剤2011
- Inventor(s)
  岩倉洋一郎、藤門範行、馬光宇
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2011-02-23
- Overseas
- Data Source
  KAKENHI-PROJECT-20220009
[Patent] 骨免疫疾患の予防・治療剤2010
- Inventor(s)
  岩倉洋一郎、藤門範行、馬光宇
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2010-02-23
- Data Source
  KAKENHI-PROJECT-20220009
[Patent] 骨免疫疾患の予防・治療剤2010
- Inventor(s)
  岩倉洋一郎、藤門範行、馬光宇
- Industrial Property Rights Holder
  国立大学法人,東京大学, 他3名
- Filing Date
  2010-02-23
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] Identification of rheumatoid arthritis-related gene by comparative analysis of two rheumatoid arthritis model mice2011
- Author(s)
  Masanori A.Murayama
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ,千葉
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] DCIR deficient mice develop ankylosing spondylitis-like pathology in humans2011
- Author(s)
  Takumi Maruhashi
- Organizer
  9^<th> Joint Meeting of the ICS and ISICR
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] DCIR欠損マウスは強直性脊椎炎様の病態を示す2011
- Author(s)
  Maruhashi Takumi
- Organizer
  第40回日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ,千葉
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] DCIR : A new therapeutic target for autoimmune disorders.2010
- Author(s)
  Guangyu Ma
- Organizer
  8th Joint Conference of the ICS and ISICR, Cytokines 2010
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] A novel arthritis-regulatory gene identified by using two mouse rheumatoid arthritis models.2010
- Author(s)
  Masanori A.Murayama
- Organizer
  8th Joint Conference of the ICS and ISICR, Cytokines 2010
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20220009
[Presentation] The roles of Dcir in bone metabolic diseases2010
- Author(s)
  Guangyu Ma
- Organizer
  14^<th> interntional congress of immunology
- Place of Presentation
  Kobe神戸ポートピアホテル神戸国際展示場
- Data Source
  KAKENHI-PROJECT-20220009

1. IWAKURA Yoichiro (10089120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 25 results
2. SAIJO Shinobu (60396877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KAKUTA Shigeru (80345032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. FUJIKADO Noriyuki (90447334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. KUSAKA Toshimasa (60466836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. KAIFU TomonoriI (90343037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. CE Tang (00572166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 有馬康伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

MA GUANGYU 馬 光宇

Research Projects

Research Products

Co-Researchers

Establishment of an IL-1-related gene-manipulated mice library, aiming at uncovering pathophysiology of disease from a view point of systems biology

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier2012

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[Journal Article] Involvement of Interleukin-1 in Lead Nitrate-Induced Hypercholesterolemia in Mice2012

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[Journal Article] Memory/effector(CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology2011

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[Journal Article] Desmoglein 3-specific CD4+T cells induce pemphigus vulgaris and interface dermatitis in mice2011

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[Journal Article] Muramyldipeptide augments the actions of lipopolysacchairde in mice by stimulating macrophages to produe pro-IL-1B and by down-regulation of suppressor of cytokine signaling 1(SOCS1)2011

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[Journal Article] Interleukin-1 Controls the Constitutive Expression of the Cyp7a1 Gene by Regulating the Expression of Cyp7a1 Transcriptional Regulators in the Mouse Liver2011

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[Journal Article] Local microbleeding facilitates IL-6-and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells2011

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[Journal Article] Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice2011

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[Journal Article] Natural Killer T Cell-Derived IL-17Mediates Lung Ischemia-Reperfusion Injury2011

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[Journal Article] Control of T(H) 17 cells occurs in the small intestine2011

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[Journal Article] Protective role of naturally occurring interleukin-17A-producing Yδ T cells in the lung at the early stage of systemic candidiasis in mice2011

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[Journal Article] Memory/effector (CD45RB(lo)) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology2011

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[Journal Article] NYAP : a phosphoprotein family that links PI3K to WAVE1 signalling in neurons2011

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[Journal Article] Muramyldipeptide augments the actions of lipopolysacchairde in mice by stimulating macrophages to produe pro-IL-1B and by down-regulation of suppressor of cytokine signaling 1 (SOCS1).2010

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[Journal Article] TNF but not IL-6 and IL17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Ill rn-/-mice.2010

MA GUANGYU 馬光宇