TAKEHARA Toshiyuki 竹原俊幸

Researcher Number	60580561
Other IDs
Affiliation (Current)	2025: 近畿大学, 大学病院, 講師
Affiliation (based on the past Project Information) *help	2019 – 2025: 近畿大学, 大学病院, 助教 2011 – 2018: 近畿大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Obstetrics and gynecology Except Principal Investigator Basic Section 56020:Orthopedics-related / Basic Section 52020:Neurology-related / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator 多能性幹細胞 / 再生医療 / ES細胞 / リプログラミング / βcatenin / β-catenin / iPS細胞 / 老化メタボライト / 老化 / 脂肪髄 … More / ヒトナイーブ型多能性幹細胞 / Gastruloid / 間葉系幹細胞 / ヒトiPS細胞 / ヒト多能性幹細胞 / 基底状態 / naive型とprimed型 / reprogram / beta catenin / 転写コアクティベーター / リプログラム / CBP/p300 / 高度生殖医療 / 熱刺激応答 / 半数体精子 / Oct4 dePE / 低酸素 / EpiSC / 生殖細胞 / 半数体細胞 / 始原生殖細胞 / 低酸素培養 / 生殖細胞誘導 … More Except Principal Investigator 間葉系幹細胞 / 老化 / 再生医療 / 幹細胞 / アンチエイジング / プロテオミクス / 脂肪髄 / SCA8 / 運動ニューロン / iPS細胞 / 筋萎縮性側索硬化症 / サルコペニア / 幹細胞老化 / scRNAseq / 未分化維持機構 / 細胞表面抗原 / 単一細胞解析 / 糖鎖解析 / 転写因子 / 骨髄由来間葉系幹細胞 / 脂肪 / 骨髄組織 / 治療法開発 / 病態解明 / リピート病 / 核酸治療薬 / 小脳失調症 / ALS / 幹細胞性（ステムネス） / ステムネス / TWIST1 / Twist1 / 転写制御 / 組織幹細胞 / ゲノム解析 / 筋衛星細胞 / 遺伝子治療 / 遺伝子発現 / 運動器 / 移植 / TGFβ / Hippo pathway / 抗ストレス / プロテオミクス解析 / TAK1 / Lyar / Hippo Pathway / Tak1 / 細胞移植 / 細胞増殖 / iPS / 非翻訳領域反復配列 / ATXN8 / ATXN8OS / 非翻訳領域反復配列延長 / 核酸医薬品 / ロコモ / Nrf2 / 酸化ストレス / miRNA / ロコモティブシンドローム Less

老化骨髄での代謝変化がもたらす脂肪髄進行メカニズムの解明と制御Principal Investigator
- Principal Investigator
  
  竹原俊幸
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Development of stemness specific markers in MSCs based on activity of transcription factor TWIST1
- Principal Investigator
  
  寺村岳士
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
The clarification of pathomechanism and the establishment of treatment for repeat expansion-associated amyotrophic lateral sclerosis
- Principal Investigator
  
  平野牧人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kindai University
加齢に伴う脂肪髄化は間葉系幹細胞におけるLyarの発現低下によるものである。
- Principal Investigator
  
  小野寺勇太
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagasaki University
  Kindai University
Creation of mesenchymal stem cells using transdifferentiation and undifferentiated induction by the transcription factor TWIST1
- Principal Investigator
  
  Mori Tatsufumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Elucidation of the Developmental Mechanism of MSCs Using Human GastruloidsPrincipal Investigator
- Principal Investigator
  
  Takehara Toshiyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Molecular mechanism of stem cell aging in the bone marrow and muscular tissues
- Principal Investigator
  
  Teramura Takeshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Identification of proteins associated with ATXN8OS-related amyotrophic lateral sclerosis and treatment of iPS cell models
- Principal Investigator
  
  Hirano Makito
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kindai University
Transforming Growth Factor beta-Activated Kinase 1 Regulates Mesenchymal Stem Cell Proliferation Through Stabilization of Yap1/Taz Proteins
- Principal Investigator
  
  ONODERA Yuta
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kindai University
Acquisition of novel naive pluripotent stem cells by activation and regulation of post-transcriptional modification on beta cateninPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Toshiyuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kindai University
Function and regulation of Nrf2 in mesenchymal stem cells
- Principal Investigator
  
  FUKUDA Kanji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Kindai University
The activation of CBP/beta-catenin signal pathway promotes reprogramming of pluripotency on mice and human cells.Principal Investigator
- Principal Investigator
  
  TAKEHARA Toshiyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kindai University
Induction of haploid germ cell from mammalian embryonic stem cellPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Toshiyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kinki University

All 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Patent

[Journal Article] LRRC15 expression indicates high level of stemness regulated by TWIST1 in mesenchymal stem cells.2023
- Author(s)
  Kensuke Toriumi, Yuta Onodera, Toshiyuki Takehara, Tatsufumi Mori, Joe Hasei, Kanae Shigi, Natsumi Iwawaki, Toshifumi Ozaki, Masao Akagi, Mahito Nakanishi, Takeshi Teramura
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 7 Pages: 106946-106946
- DOI
  10.1016/j.isci.2023.106946
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09413
[Journal Article] Fibrinogen supports self-renewal of mesenchymal stem cells under serum-reduced condition through autophagy activation2023
- Author(s)
  Tatsufumi Mori, Masatsugu Igarashi, Yuta Onodera, Toshiyuki Takehara, Maki Itokazu, Takeshi Teramura
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 651 Pages: 70-78
- DOI
  10.1016/j.bbrc.2023.02.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09413
[Journal Article] Depletion of NIMA-related kinase Nek2 induces aberrant self-renewal and apoptosis in stem/progenitor cells of aged muscular tissues2022
- Author(s)
  Mori Tatsufumi、Onodera Yuta、Itokazu Maki、Takehara Toshiyuki、Shigi Kanae、Iwawaki Natsumi、Akagi Masao、Teramura Takeshi
- Journal Title
  
  Mechanisms of Ageing and Development
  
  Volume: 201 Pages: 111619-111619
- DOI
  10.1016/j.mad.2022.111619
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09562, KAKENHI-PROJECT-20H03810
[Journal Article] Adipose-derived exosomes block muscular stem cell proliferation in aged mouse by delivering miRNA Let-7d-3p that targets transcription factor HMGA22022
- Author(s)
  Itokazu Maki、Onodera Yuta、Mori Tatsufumi、Inoue Shinji、Yamagishi Kotaro、Moritake Akihiro、Iwawaki Natsumi、Shigi Kanae、Takehara Toshiyuki、Higashimoto Yuji、Akagi Masao、Teramura Takeshi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 7 Pages: 102098-102098
- DOI
  10.1016/j.jbc.2022.102098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11325, KAKENHI-PROJECT-22K09413, KAKENHI-PROJECT-20H03810
[Journal Article] Transforming Growth Factor β-Activated Kinase 1 Regulates Mesenchymal Stem Cell Proliferation Through Stabilization of Yap1/Taz Proteins.2019
- Author(s)
  Onodera Y, Teramura T, Takehara T, Fukuda K.
- Journal Title
  
  Stem cells
  
  Volume: 37(12) Issue: 12 Pages: 1595-1605
- DOI
  10.1002/stem.3083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09562, KAKENHI-PROJECT-17K11036
[Journal Article] Inflammation-associated miR-155 activates differentiation of muscular satellite cells2018
- Author(s)
  Onodera Yuta、Teramura Takeshi、Takehara Toshiyuki、Itokazu Maki、Mori Tatsufumi、Fukuda Kanji
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 10 Pages: 204860-204881
- DOI
  10.1371/journal.pone.0204860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01487, KAKENHI-PROJECT-17K11036, KAKENHI-PROJECT-16K01484, KAKENHI-PROJECT-16K21508
[Journal Article] Inflammation-induced miRNA-155 inhibits self-renewal of neural stem cells via suppression of CCAAT/enhancer binding protein β (C/EBPβ) expression2017
- Author(s)
  Obora K, Onodera Y, Takehara T, Frampton J, Hasei J, Ozaki T, Teramura T, Fukuda K
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 43604-43604
- DOI
  10.1038/srep43604
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861217, KAKENHI-PROJECT-16K01484, KAKENHI-PROJECT-16K21508
[Journal Article] miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells2017
- Author(s)
  Onodera Yuta、Teramura Takeshi、Takehara Toshiyuki、Obora Kayoko、Mori Tatsufumi、Fukuda Kanji
- Journal Title
  
  Aging Cell
  
  Volume: 16 Issue: 6 Pages: 1369-1380
- DOI
  10.1111/acel.12680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K01484, KAKENHI-PROJECT-16K21508
[Journal Article] Cdh2 stabilizes FGFR1 and contributes to primed-state pluripotency in mouse epiblast stem cells2015
- Author(s)
  Toshiyuki Takehara
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 14722-14722
- DOI
  10.1038/srep14722
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861216, KAKENHI-PROJECT-26861217
[Journal Article] Induction of Functional Mesenchymal Stem Cells in Severe Hypoxic Condition from Rabbit Embryonic Stem Cells2013
- Author(s)
  Teramura T, Onodera Y, Takehara T, Frampton J, Matsuoka T, Ito S, Nakagawa K, Miki Y, Hosoi Y, Hamanishi C, and Fukuda K
- Journal Title
  
  Cell Transplantation
  
  Volume: 22(2) Pages: 309-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791859
[Journal Article] c-Jun N-terminal kinase (JNK) mediates Rho/ROCK induced Sox9 diminution in chondrocytes2013
- Author(s)
  Onodera Y, Teramura T, Takehara T, Fukuda K
- Journal Title
  
  Acta Medica Kinki University
  
  Volume: 巻38 No.2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791859
[Journal Article] Generation of Embryonic Stem Cell Lines from Immature Rabbit Ovarian Follicles2013
- Author(s)
  Teramura T, Sugimoto H, Frampton J, Kida Y, Nakano M, Kawakami M, Izumi H, Fukunaga N, Onodera Y, Takehara T, Fukuda K, Hosoi Y
- Journal Title
  
  Stem Cells Dev
  
  Volume: 22(6) Pages: 928-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791859
[Journal Article] Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants2012
- Author(s)
  Nakagawa K, Teramura T, Takehara T, Onodera Y, Hamanishi C, Akagi M, Fukuda K
- Journal Title
  
  Inflamm Res
  
  Volume: 61(10) Pages: 1093-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791859
[Journal Article] Reduced oxygen concentration enhances conversion of embryonic stem cells to epiblast stem cells2012
- Author(s)
  Takehara T, Teramura T, Onodera Y, Hamanishi C, Fukuda K
- Journal Title
  
  Stem Cells Dev
  
  Volume: 21(8) Pages: 1239-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791859
[Journal Article] Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells2012
- Author(s)
  Teramura T, Takehara T, Onodera Y, Nakagawa K, Hamanishi C, Fukuda K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 417(2) Pages: 836-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791859
[Journal Article] Reduced Oxygen Concentration Enhances Conversion of Embryonic Stem Cells to Epiblast Stem Cells.2011
- Author(s)
  Takehara T,
- Journal Title
  
  Stem cells and Development
  
  Volume: Epub ahead of print Issue: 8 Pages: 1239-1249
- DOI
  10.1089/scd.2011.0322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791859
[Patent] βカテニンこファクター阻害剤によるNaive型多能性幹細胞の作製法2019
- Inventor(s)
  竹原俊幸
- Industrial Property Rights Holder
  竹原俊幸
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K11037
[Presentation] 副甲状腺組織再生を目指した多能性幹細胞由来副甲状腺細胞の誘導の試み2023
- Author(s)
  竹原俊幸
- Organizer
  第22回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-21K09313
[Presentation] Phenotypic variation and therapeutic strategy of SCA8-associated amyotrophic lateral sclerosis2022
- Author(s)
  Makito Hirano, Toshiyuki Takehara, Shigeo Murayama, Yuishin Izumi, Makoto Samukawa, Tomoyasu Matsubara, Yuko Saito, Kazumasa Saigoh, Yusaku Nakamura, Kanji Fukuda, Susumu Kusunoki, Yoshitaka Nagai
- Organizer
  第63回　日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K07984
[Presentation] NINA-related kinase (NEK2)は加齢マウスでの筋衛星細胞の減少に関与する2022
- Author(s)
  森樹史, 小野寺勇太, 信貴香苗, 糸数万紀, 岩脇菜摘, 竹原俊幸, 赤木將男, 寺村岳士
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K09562
[Presentation] 加齢脂肪組織由来エクソソームはmiRNA Let7d-Hmga2経路で筋衛星細胞の細胞増殖を阻害する2022
- Author(s)
  糸数万紀, 小野寺勇太, 森樹史, 岩脇菜摘, 信貴香苗, 竹原俊幸, 福田寛二, 寺村岳士
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K09562
[Presentation] Phenotypic variation and therapeutic strategy of SCA8-associated amyotrophic lateral sclerosis2022
- Author(s)
  Makito Hirano, Toshiyuki Takehara, Shigeo Murayama, Yuishin Izumi, Makoto Samukawa, Tomoyasu Matsubara, Yuko Saito, Kazumasa Saigoh, Yusaku Nakamura, Kanji Fukuda Susumu Kusunoki, Yoshitaka Nagai
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07510
[Presentation] 核小体タンパク質LYARは骨髄間葉系幹細胞の脂肪分化を制御する2022
- Author(s)
  小野寺勇太, 信貴香苗, 糸数万紀, 森樹史, 岩脇菜摘, 竹原俊幸, 福田寛二, 寺村岳士
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K09562
[Presentation] 骨髄間葉系幹細胞におけるTak1の抑制は静止期を誘導し移植細胞の定着効率を向上させる2021
- Author(s)
  小野寺勇太、寺村岳士、竹原俊幸、福田寛二
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03810
[Presentation] Tak1はYap1/Tazとの相互作用を介し骨髄間葉系幹細胞（BMMSC）の細胞周期を制御する。2021
- Author(s)
  福田寛二、小野寺勇太、寺村岳士、竹原俊幸、福田寛二
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03810
[Presentation] Tak1は増殖性サイトカイン依存性のBMMSC増殖を制御し、その阻害は可逆的増殖停止を誘導する2021
- Author(s)
  信貴香苗、小野寺勇太、竹原俊幸、寺村岳士、福田寛二
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03810
[Presentation] 骨髄間葉系幹細胞におけるTak1の抑制は静止期を誘導し移植細胞の定着効率を向上させる。2020
- Author(s)
  小野寺勇太　寺村岳士　竹原俊幸　福田寛二
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K09562
[Presentation] Tak1はYap1/Tazとの相互作用を介し骨髄間葉系幹細胞（BMMSC）の細胞周期を制御する。2020
- Author(s)
  福田寛二　小野寺勇太　信貴香苗　竹原俊幸　寺村岳士
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K09562
[Presentation] Tak1は増殖性サイトカイン依存性のBMMSC増殖を制御し、その阻害は可逆的増殖停止を誘導する。2020
- Author(s)
  信貴香苗　小野寺勇太　竹原俊幸　寺村岳士　福田寛二
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K09562
[Presentation] 異なる多能性状態:Naive型及びPrimed型に対するβ-cateninの役割2020
- Author(s)
  竹原俊幸、小野寺勇太、福田寛二、寺村岳士
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K11037
[Presentation] 第15回日本生殖発生医学会学術集会2020
- Author(s)
  竹原俊幸、小野寺勇太、福田寛二、寺村岳士
- Organizer
  β-cateninを標的とした新たなヒトNaive型多能性幹細胞獲得の試み
- Data Source
  KAKENHI-PROJECT-17K11037
[Presentation] 骨髄間葉系幹細胞（BMMSC）におけるTGFβ-activated kinase (Tak1)の抑制は静止期を誘導し移植細胞の定着効率を向上させる2020
- Author(s)
  小野寺勇太　寺村岳士　信貴香苗　森樹史　竹原俊幸　福田寛二
- Organizer
  第33回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-19K09562
[Presentation] 間葉系幹細胞におけるTGFb-activated kinase (TAK1)の抑制はYap1の制御を介して静止期を誘導し細胞移植の効率に寄与する。2019
- Author(s)
  小野寺勇太　竹原俊幸　寺村岳士　福田寛二
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19K09562
[Presentation] β-catenin経路に着目した新規iPS細胞誘導技術の開発2017
- Author(s)
  竹原俊幸、寺村岳士、小野寺勇太、福田寛二
- Organizer
  第16回日本再生医療学会
- Place of Presentation
  仙台国際センター宮城県
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-26861216
[Presentation] The activation of CBP/beta-catenin signal pathway is involved in the transition from primed- to naïve state on mice pluripotent stem cells2015
- Author(s)
  Toshiyuki Takehara
- Organizer
  International Society for Stem Cell Research
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861216
[Presentation] ウサギ体外成熟卵子をレシピエント卵子とした核移植胚由来ES細胞の樹立2014
- Author(s)
  竹原俊幸、木田雄太、中野美穂、杉本浩伸、寺村岳士、小野寺勇太、細井美彦、福田寛二
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都国際会議場、京都
- Year and Date
  2014-03-04
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] CBP/β-cateninシグナル経路の活性化がマウス多能性幹細胞の形質転換に及ぼす影響2013
- Author(s)
  竹原俊幸、寺村岳士、小野寺勇太、福田寛二
- Organizer
  第12回日本再生医療学会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] INDUCTION OF DIFFERENTIATION INTO PRIMORDIAL GERM CELL FROM EPIBLAST STEM CELL DERIVED FROM MOUSE EMBRYONIC STEM CELL2013
- Author(s)
  Toshiyuki Takehara, Takeshi Teramura, Yuta Onodera, Kanji Fukuda
- Organizer
  11^<th> International Society for Stem Cell Research, Annual Meeting
- Place of Presentation
  ボストン、アメリカ
- Year and Date
  2013-06-13
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] INDUCTION OF DIFFERENTIATION INTO PRIMORDIAL GERM CELL FROM EPIBLAST STEM CELL DERIVED FROM MOUSE EMBRYONIC STEM CELL2013
- Author(s)
  Toshiyuki Takehara
- Organizer
  11th International Society for Stem Cell Research
- Place of Presentation
  Boston MA, USA
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] INDUCTION OF DIFFERENTIATION INTO PRIMORDIAL GERM CELL FROM EPIBLAST STEM CELL DERIVED FROM MOUSE EMBRYONIC STEM CELL2013
- Author(s)
  Toshiyuki Takehara ほか3人
- Organizer
  ISSCR 11th
- Place of Presentation
  Boston MA, USA
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] マウスES細胞からの生殖細胞誘導の試み2012
- Author(s)
  竹原俊幸、寺村岳士、小野寺勇太、浜西千秋、福田寛二
- Organizer
  第11回日本再生医療学会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2012-06-12
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] Differentiation reversibility between mouse embryonic stem cells and epiblast stem cells2012
- Author(s)
  Toshiyuki Takehara, Takeshi Teramura, Yuta Onodera, Chiaki Hamanishi, Kanji Fukuda
- Organizer
  10^<th> International Society for Stem Cell Research, Annual Meeting
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] ヒトiPS細胞からの間葉系幹細胞の分化誘導2012
- Author(s)
  竹原俊幸
- Organizer
  第25回日本軟骨代謝学会
- Place of Presentation
  ウィル愛知（名古屋市）
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] マウスES細胞からの生殖細胞誘導の試み2012
- Author(s)
  竹原俊幸　他3人
- Organizer
  第11回日本再生医療学会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] Reduced oxygen concentration enhances conversion of embryonic stem cells to epiblast stem cells2011
- Author(s)
  竹原俊幸
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23791859
[Presentation] THE ACTIVATION OF CBP/BETA-CATENIN SIGNAL PATHWAY IS INVOLVED IN THE TRANSITION FROM PRIMED- TO NAIVE STATE ON MICE PLURIPOTENT STEM CELLS
- Author(s)
  Toshiyuki Takehara
- Organizer
  International Society for Stem Cell Research
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2015-06-24 – 2015-06-27
- Data Source
  KAKENHI-PROJECT-26861216

1. Teramura Takeshi (40460901)

# of Collaborated Projects: 9 results

# of Collaborated Products: 20 results
2. ONODERA Yuta (30510911)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
3. FUKUDA Kanji (50201744)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. Hirano Makito (50347548)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. Mori Tatsufumi (40760492)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 村川泰裕 (50765469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 丹羽淳子 (60122082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高橋英夫 (60335627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 末盛博文 (90261198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 味八木茂 (10392490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 舘野浩章 (30450670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 後藤公志 (00437229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 糸数万紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 東本有司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKEHARA Toshiyuki 竹原 俊幸

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老化骨髄での代謝変化がもたらす脂肪髄進行メカニズムの解明と制御Principal Investigator

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Elucidation of the Developmental Mechanism of MSCs Using Human GastruloidsPrincipal Investigator

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Acquisition of novel naive pluripotent stem cells by activation and regulation of post-transcriptional modification on beta cateninPrincipal Investigator

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The activation of CBP/beta-catenin signal pathway promotes reprogramming of pluripotency on mice and human cells.Principal Investigator

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Induction of haploid germ cell from mammalian embryonic stem cellPrincipal Investigator

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[Journal Article] LRRC15 expression indicates high level of stemness regulated by TWIST1 in mesenchymal stem cells.2023

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[Journal Article] Fibrinogen supports self-renewal of mesenchymal stem cells under serum-reduced condition through autophagy activation2023

TAKEHARA Toshiyuki 竹原俊幸