• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

TANIMOTO Kousuke  谷本 幸介

ORCIDConnect your ORCID iD *help
… Alternative Names

TANIMOTO Kosuke  谷本 幸介

Less
Researcher Number 60611613
Other IDs
Affiliation (Current) 2025: 東京科学大学, 大学院医歯学総合研究科, 特任講師
Affiliation (based on the past Project Information) *help 2023: 長崎大学, 熱帯医学・グローバルヘルス研究科, 客員研究員
2013 – 2022: 東京医科歯科大学, 難治疾患研究所, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor therapeutics
Except Principal Investigator
Complex systems / Basic Section 54030:Infectious disease medicine-related / Medium-sized Section 50:Oncology and related fields / Tumor biology / Tumor diagnostics
Keywords
Principal Investigator
スプライシング制御 / がん体細胞変異 / データベース / TCGA / がん体細胞バリアント / スプライシング / エピゲノム / HDAC阻害剤 / ヒストンアセチル化 / ヒストン脱アセチル化酵素阻害剤 … More
Except Principal Investigator
… More がん / オートファジー / マイクロRNA / ゲノム / バイオマーカー / オミクス解析 / オミクス / 分子標的治療 / システム生物学 / エピゲノム / 遺伝子発現解析 / 回復期 / 急性期 / シングルセル解析 / T細胞受容体 / メモリー細胞 / エフェクター細胞 / シングルセルmRNA発現解析 / T 細胞レパトワ解析 / T細胞レセプター遺伝子 / 重症型デング熱 / 細胞障害性T細胞 / ヒト免疫応答性 / ワクチン開発 / デング熱 / 代謝 / 代謝酵素 / 染色体構造 / ヒストンメチル化 / 核内遺伝子配置 / CREB / HIF / クロマチン構造 / 遺伝子発現 / 低酸素応答 / 癌 / 核酸創薬 / 既存薬再配置 / 浸潤・転移 / がん特性 / 核酸抗がん薬 / がん抑制型マイクロRNA / がん悪性特性 / DR / がん代謝異常 / がん細胞文脈 / DDS / 核酸医薬 / 上皮間葉転換(EMT) / 細胞文脈 / chromothripsis / 全ゲノムシークエンス / 次世代型シークエンサー / HOC313 / 次世代シークエンサー / 口腔がん / DNA二重鎖切断 / マイクロビーム照射装置 / ゲノム不安定性 / ゲノム再構成 / 染色体粉砕 / Chromothripsis / 分子標的薬 / DNAメチル化 / 癌抑制遺伝子 / 癌遺伝子 / 難治がん / ビメンチン / EMT / 治療標的 / p62 / 上皮間葉転換 / がん個別化医療 / 遺伝子ネットワーク / がん抑制遺伝子 / がん遺伝子 / 分子標的 / 薬剤耐性 / miRNA / NRF2 / バイオリソース / がん治療標的分子 / ゲノム・エピゲノム解析 Less
  • Research Projects

    (8 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (12 People)
  •  Single cell analysis of TCR genotypes of CTL at recovery phase of acute Dengue infection

    • Principal Investigator
      Hirayama Kenji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 54030:Infectious disease medicine-related
    • Research Institution
      Nagasaki University
  •  Massive identification of somatic variants in exonic splicing enhancers using public databasesPrincipal Investigator

    • Principal Investigator
      Tanimoto Kousuke
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Comprehensive analysis of 3D nuclear gene position involved in malignant transformation of hypoxic cancer

    • Principal Investigator
      Nakayama Koh
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Asahikawa Medical College
      Tokyo Medical and Dental University
  •  exploring direct target genes of HDAC inhibitor for epigenomic evidenced based medicinePrincipal Investigator

    • Principal Investigator
      Tanimoto Kousuke
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Tokyo Medical and Dental University
  •  Establishment of novel concept for cancer diagnostics and therapeutics based on the systematic comprehension of cellular context in cancer

    • Principal Investigator
      Inazawa Johji
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo Medical and Dental University
  •  Comprehensive understanding of molecular carcinogenesis through omics analysis and development of molecular diagnostics for personalized medicine

    • Principal Investigator
      Johji Inazawa
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Tumor diagnostics
    • Research Institution
      Tokyo Medical and Dental University
  •  Chromothripsis-like pattern in cancer-cell genome after irradiation by a focused vertical micro-beam system, SPICE

    • Principal Investigator
      INAZAWA Johji
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Tokyo Medical and Dental University
  •  Integrative omics analysis to explore molecular targets and biomarkers for personalized medicine in cancer

    • Principal Investigator
      INAZAWA Johji
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo Medical and Dental University

All 2019 2018 2017 2016 2015

All Journal Article Presentation Patent

  • [Journal Article] Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas2019

    • Author(s)
      Tanimoto Kousuke、Muramatsu Tomoki、Inazawa Johji
    • Journal Title

      Cancer Medicine

      Volume: 8 Issue: 17 Pages: 7372-7384

    • DOI

      10.1002/cam4.2619

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-18H02688, KAKENHI-PROJECT-18K15305
  • [Journal Article] miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein2018

    • Author(s)
      Tonouchi Erina、Gen Yasuyuki、Muramatsu Tomoki、Hiramoto Hidekazu、Tanimoto Kousuke、Inoue Jun、Inazawa Johji
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 4482-4482

    • DOI

      10.1038/s41598-018-22767-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K14630, KAKENHI-PROJECT-15K19040, KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-18H02688
  • [Journal Article] miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer2017

    • Author(s)
      Hiramoto Hidekazu、Muramatsu Tomoki、Ichikawa Daisuke、Tanimoto Kousuke、Yasukawa Satoru、Otsuji Eigo、Inazawa Johji
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1

    • DOI

      10.1038/s41598-017-04191-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-16K14630
  • [Journal Article] Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma.2017

    • Author(s)
      Nagata H, Kozaki K, Muramatsu T, Hiramoto H, Tanimoto K, Fujiwara N, Imoto S, Ichikawa D, Otsuji E, Miyano S, Kawano T, Inazawa J
    • Journal Title

      Oncotarget

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05908
  • [Journal Article] Genome-wide screening of DNA methylation associated with lymph node metastasis in esophageal squamous cell carcinoma2017

    • Author(s)
      Nagata Hiroaki、Kozaki Ken-Ichi、Muramatsu Tomoki、Hiramoto Hidekazu、Tanimoto Kousuke、Fujiwara Naoto、Imoto Seiya、Ichikawa Daisuke、Otsuji Eigo、Miyano Satoru、Kawano Tatsuyuki、Inazawa Johji
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 23 Pages: 37740-37750

    • DOI

      10.18632/oncotarget.17147

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05908, KAKENHI-PLANNED-15H05912, KAKENHI-PROJECT-16K14630
  • [Journal Article] Receptor tyrosine kinase amplification is predictive of distant metastasis in patients with oral squamous cell carcinoma.2016

    • Author(s)
      Oikawa Y, Morita KI, Kayamori K, Tanimoto K, Sakamoto K, Katoh H, Ishikawa S, Inazawa J, Harada H
    • Journal Title

      Cancer Sci.

      Volume: 108 Issue: 2 Pages: 256-266

    • DOI

      10.1111/cas.13126

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-16H02481, KAKENHI-PROJECT-16H05510
  • [Journal Article] Mitochondrial Apoptosis Pathway and Enhances Chemotherapy-Induced Cytotoxicity.2015

    • Author(s)
      2. Fujiwara N, Inoue J, Kawano T, Tanimoto K, Kozaki K, Inazawa J
    • Journal Title

      Cancer Res.

      Volume: 75 Issue: 18 Pages: 3890-3901

    • DOI

      10.1158/0008-5472.can-15-0257

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K08301, KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-26670815, KAKENHI-PROJECT-26293067
  • [Journal Article] Simultaneous detection of both single nucleotide variations and copy number alterations by next-generation sequencing in Gorlin syndrome2015

    • Author(s)
      Morita K, Naruto T, Tanimoto K, Yasukawa C, Oikawa Y, Masuda K, Imoto I, Inazawa J, Omura K, Harada H.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 11 Pages: e0140480-e0140480

    • DOI

      10.1371/journal.pone.0140480

    • NAID

      120006871193

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08949, KAKENHI-PROJECT-15K15735, KAKENHI-PLANNED-15H05908, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-26293304
  • [Patent] 食道がんのリンパ節転移可能性のデータ取得方法2017

    • Inventor(s)
      稲澤譲治、村松智輝、永田啓明、谷本幸介、河野辰幸 他2名
    • Industrial Property Rights Holder
      国立大学法人東京医科歯科大学、株式会社ビー・エム・エル
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-036122
    • Filing Date
      2017-02-28
    • Data Source
      KAKENHI-PLANNED-15H05908
  • [Presentation] 統合的 mRNA, miRNA 発現情報を基盤とした独自のマイクロ RNA標的遺伝子予測データベースの構築2019

    • Author(s)
      内藤諒、村松智輝、谷本幸介、稲澤譲治
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PLANNED-15H05908
  • [Presentation] miR-3140 suppresses tumor cell growth by targeting BRD4 via its coding sequence and downregulates the BRD4-NUT fusion oncoprotein2018

    • Author(s)
      Muramatsu T, Tonouchi E, Gen Y, Hiramoto H, Tanimoto K, Inoue J, Inazawa J
    • Organizer
      AACR Annual Meeting 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05908
  • [Presentation] Exploring target genes of eukaryotic initiation factor 5A in cancer using RNA sequence analysis2016

    • Author(s)
      Muramatsu T, Tanimoto K, Inazawa J
    • Organizer
      AACR
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2016-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05908
  • [Presentation] Exploring target genes of eukaryotic initiation factor 5A in cancer using RNA sequence analysis2016

    • Author(s)
      Muramatsu T, Tanimoto K, Inazawa J
    • Organizer
      AACR
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2016-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25250019
  • [Presentation] Exploring target genes of eukaryotic initiation factor 5A in cancer using RNA sequence analysis2016

    • Author(s)
      Muramatsu T, Tanimoto K, Inazawa J
    • Organizer
      AACR2016 Annual Meeting
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2016-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-15H05908
  • 1.  INAZAWA Johji (30193551)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 2.  INOUE Jun (50568326)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 3.  KOZAKI Ken-ichi (50270715)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  Muramatsu Tomoki (90732553)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 5.  Nakayama Koh (10451923)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Hirayama Kenji (60189868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  玄 泰行 (80596156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  谷水 直樹 (00333386)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  與那城 亮 (60453809)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  水上 修作 (00508971)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  グエン フイティエン (20457526)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  増田 清士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi