Hoang Hai ＨｏａｎｇＨａｉ

… Alternative Names

HOANG HAI ホアンハイ

HOANG Hai ホアンハイ

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Researcher Number	60623246
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 特任講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 大阪公立大学, 大学院医学研究科, 研究員 2021: 大阪市立大学, 大学院医学研究科, 研究員 2015 – 2017: 大阪市立大学, 大学院医学研究科, 研究員 2014: 大阪市立大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords	Principal Investigator pancreatic tumor / liver tumor / Demethylation / Promoter / Cytoglobin / Liver cancer / DAC / Huh-7 / Liver tumor / CYGB promoter / DNA methylation / 遺伝子 / HCC SNP … More Except Principal Investigator … More ROS / TGF-β / TGFβ / コラーゲン / Cytoglobin / 肝線維化 / 星細胞 / マイクロRNA / SVR / 肝発癌 / C型肝炎ウイルス Less

肝細胞のがん化における細胞間相互作用を介した星細胞の役割
- Principal Investigator
  
  河田則文
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
Cytoglobin (CYGB)-overexpression and targeted demethylation of CYGB promoter impair liver and pancreatic tumor growthPrincipal Investigator
- Principal Investigator
  
  HOANG HAI
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Osaka Metropolitan University
  Osaka City University
Hepatic pathology of patients achieved sustained hepatitis C viral response
- Principal Investigator
  
  TAMORI Akihiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University
Study on miRNA expression and single nucleotide polymorphisms in hepatocellular carcinoma after HCV eradicationPrincipal Investigator
- Principal Investigator
  
  HOANG HAI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University

All 2024 2023 2022 2017 2016 2015 Other

All Journal Article Presentation Book Other

[Book] Liver Pathophysiology: Therapies and Antioxidants2017
- Author(s)
  Le Thi Thanh Thuy, Tuong Thi Van Thuy, Hoang Hai, and Norifumi Kawada
- Total Pages
  914
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-26860522
[Journal Article] Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40?CD40L Linkage2024
- Author(s)
  Ngo Hanh Vinh、Thanh Le Thuy Thi、Vu Hieu Ngoc、Hoang Hai、Ikenaga Hiroko、Sato-Matsubara Misako、Uchida-Kobayashi Sawako、Urushima Hayato、Van Nguyen Khanh、Nguyen Ha Thi、Shinkawa Hiroji、Kubo Shoji、Ohtani Naoko、Enomoto Masaru、Tamori Akihiro、Kawada Norifumi
- Journal Title
  
  The American Journal of Pathology
  
  Volume: in press Issue: 7 Pages: 1230-1247
- DOI
  10.1016/j.ajpath.2024.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07921, KAKENHI-PROJECT-21K07990, KAKENHI-PROJECT-23K24322
[Journal Article] Increased spine bone density in patients with chronic hepatitis B switched to tenofovir alafenamide: A prospective, multinational study2023
- Author(s)
  Ogawa E, Jun DW, Toyoda H, Hsu YC, Yoon EL, Ahn SB, Yeh ML, Do S, Trinh HN, Takahashi H, Enomoto M, Kawada N, Yasuda S, Tseng CH, Kawashima K, Lee HA, Inoue K, Haga H, Do AT, Maeda M, Hoang JH, Cheung R, Ueno Y, Eguchi Y, Furusyo N, Yu ML, Tanaka Y, Nguyen MH
- Journal Title
  
  Alimentary Pharmacology & Therapeutics
  
  Volume: 59 Issue: 2 Pages: 239-248
- DOI
  10.1111/apt.17785
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07989, KAKENHI-PROJECT-23K24322
[Journal Article] Nitric Oxide Derived from Cytoglobin-Deficient Hepatic Stellate Cells Causes Suppression of Cytochrome c Oxidase Activity in Hepatocytes2023
- Author(s)
  Yoshinori Okina, Misako Sato-Matsubara, Yasutoshi Kido, Hayato Urushima, Atsuko Daikoku, Chiho Kadono, Yu Nakagama, Yuko Nitahara, Truong Huu Hoang, Le Thi Thanh Thuy, Tsutomu Matsubara, Naoko Ohtani, Kazuo Ikeda, Katsutoshi Yoshizato, Norifumi Kawada.
- Journal Title
  
  Antioxid Redox Signal.
  
  Volume: 38 Pages: 463-479
- DOI
  10.1089/ars.2021.0279
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-20H00335, KAKENHI-PROJECT-21H03369, KAKENHI-PROJECT-23K21359, KAKENHI-PROJECT-21K06757, KAKENHI-PROJECT-20K16226, KAKENHI-PROJECT-23K24322
[Journal Article] Soluble Immune Checkpoint Protein CD27 Is a Novel Prognostic Biomarker of Hepatocellular Carcinoma Development in Hepatitis C Virus?Sustained Virological Response Patients2022
- Author(s)
  Dong Minh Phuong、Thuy Le Thi Thanh、Hoang Dinh Viet、Hai Hoang、Hoang Truong Huu、Sato-Matsubara Misako、Hieu Vu Ngoc、Daikoku Atsuko、Hanh Ngo Vinh、Urushima Hayato、Dat Ninh Quoc、Uchida-Kobayashi Sawako、Enomoto Masaru、Ohtani Naoko、Tamori Akihiro、Kawada Norifumi
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 192 Issue: 10 Pages: 1379-1396
- DOI
  10.1016/j.ajpath.2022.07.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07921, KAKENHI-PROJECT-21K07990, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-20K16226, KAKENHI-PROJECT-21H03369, KAKENHI-PROJECT-23K24322
[Journal Article] Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species2022
- Author(s)
  Hoang Dinh Viet、Thuy Le Thi Thanh、Hai Hoang、Hieu Vu Ngoc、Kimura Kenjiro、Oikawa Daisuke、Ikura Yoshihiro、Dat Ninh Quoc、Hoang Truong Huu、Sato-Matsubara Misako、Dong Minh Phuong、Hanh Ngo Vinh、Uchida-Kobayashi Sawako、Tokunaga Fuminori、Kubo Shoji、Ohtani Naoko、Yoshizato Katsutoshi、Kawada Norifumi
- Journal Title
  
  Oncogenesis
  
  Volume: 11 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41389-022-00389-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06873, KAKENHI-PROJECT-21K07921, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-22K18385, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-21H03369, KAKENHI-PUBLICLY-21H00291, KAKENHI-PROJECT-23K24322
[Journal Article] Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms.2022
- Author(s)
  Huu Hoang T, Sato-Matsubara M, Yuasa H, Matsubara T, Thuy LTT, Ikenaga H, Phuong DM, Hanh NV, Hieu VN, Hoang DV, Hai H, Okina Y, Enomoto M, Tamori A, Daikoku A, Urushima H, Ikeda K, Dat NQ, Yasui Y, Shinkawa H, Kubo S, Yamagishi R, Ohtani N, Yoshizato K, Gracia-Sancho J, Kawada N.
- Journal Title
  
  Sci Adv.
  
  Volume: 8(39) Issue: 39 Pages: 5525-5525
- DOI
  10.1126/sciadv.abo5525
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06757, KAKENHI-PROJECT-21K07968, KAKENHI-PROJECT-21K07990, KAKENHI-PROJECT-22K08083, KAKENHI-PROJECT-20K16226, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H03369, KAKENHI-PROJECT-23K21359, KAKENHI-PROJECT-23K24322
[Journal Article] Outcomes for Cirrhotic Patients with Hepatitis C Virus 1b Treated with Asunaprevir and Daclatasvir Combination2017
- Author(s)
  Tamori Akihiro、Hai Hoang、Uchida-Kobayashi Sawako、Enomoto Masaru、Kozuka Ritsuzo、Motoyama Hiroyuki、Kawamura Etsushi、Hagihara Atsushi、Teranishi Yuga、Yoshida Kanako、Morikawa Hiroyasu、Murakami Yoshiki、Kawada Norifumi
- Journal Title
  
  Annals of Hepatology
  
  Volume: 16 Issue: 5 Pages: 734-741
- DOI
  10.5604/01.3001.0010.2732
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09369, KAKENHI-PROJECT-17K09467, KAKENHI-PROJECT-15K09019
[Journal Article] Pathophysiological role of cytoglobin, the fourth globin in mammals, in liver diseases.2016
- Author(s)
  Thuｙ　Le　ＴT, Nguen Thi Thanh Hai, Hoang Hai, Norifumi Kawada.
- Journal Title
  
  Histol Histopathol.
  
  Volume: 31 Pages: 257-267
- Data Source
  KAKENHI-PROJECT-26860522
[Presentation] Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression.2024
- Author(s)
  Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Nguyen Thi Ha, Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Cell-cell interaction of LSECs-HSCs in the microenvironment of Diethyl nitrosamine treated Cytoglobin Knock-out mice.2024
- Author(s)
  Nguyen Thi Ha, Le Thi Thanh Thuy, Hoang Hai, Pham Minh Duc, Ngo Vinh Hanh, Nguyen Van Khanh, Nguyen Tran Quang Sang, Inoue Mana, Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Soluble PD-1 and BTLA proteins as biomarkers for predicting the anti-HBV treatment responsiveness.2024
- Author(s)
  Hoang Hai, Masaru Enomoto, Le Thi Thanh Thuy, Naoshi Odagiri, Kohei Kotani, Hiroyuki Motoyama, Ritsuzo Kozuka, Atsushi Hagihara, Etsushi Kawamura, Hideki Fujii, Sawako Uchida-Kobayashi, and Norifumi Kawada
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Baseline sCD27, sCD28, and sCD40 levels - novel predictors of HCC development in HCV-SVR patients2023
- Author(s)
  Le Thi Thanh Thuy, Minh Phuong Dong, Hoang Hai, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Norifumi Kawada
- Organizer
  the 32nd Annual Meeting of Asian Pacific Association for the Study of the Liver (APASL)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Role of Cytoglobin in Liver Fibrosis and Steatohepatitis.2023
- Author(s)
  Le Thi Thanh Thuy, Hoang Hai, and Kawada N
- Organizer
  The 3rd Japan Society of Hepatology International Liver Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression.2023
- Author(s)
  Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Nguyen Thi Ha and Norifumi Kawada
- Organizer
  第３７回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] The promising therapeutics of recombinant human cytoglobin against acetaminophen-induced liver injury.2023
- Author(s)
  Pham Minh Duc, Le Thi Thanh Thuy, Hoang Hai, Nguyen Thi Ha, Vu Ngoc Hieu, Kawada N
- Organizer
  The 3rd Japan Society of Hepatology International Liver Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] CD40 expression in liver cancer cells is upregulated by CD4+T cells through IFN gamma and ERK 1/2 pathway.2023
- Author(s)
  Ngo Vinh Hanh, Le Thi Thanh Thuy, Hoang Hai, Vu Ngoc Hieu, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Kawada N
- Organizer
  European Association for the Study of Liver Annual Congress (EASL) 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Therapeutic effect of recombinant human Cytoglobin against mouse liver fibrosis and stellate cell activation via ROS scavenger function and activation of JAK-STAT1 pathway.2023
- Author(s)
  Kawada N, Pham Minh Duc, Le Thi Thanh Thuy, and Hoang Hai
- Organizer
  European Association for the Study of Liver Annual Congress (EASL) 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Down-regulation of CYGB expression by promoter methylation is associated with hepatocellular carcinoma progression2022
- Author(s)
  Hoang Hai
- Organizer
  第36回肝類洞壁細胞研究会学術集会
- Data Source
  KAKENHI-PROJECT-21K07921
[Presentation] Anti-fibrotic Capacity of Extracellular Globins via Scavenging Reactive Oxygen Species2022
- Author(s)
  Le Thi Thanh Thuy, Vu Ngoc Hieu, Hoang Hai, and Norifumi Kawada
- Organizer
  XXI International Conference on Oxygen Binding and Sensing Proteins (O2BIP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Soluble immune checkpoint protein CD27 is a novel prognostic predictor of HCC development in HCV-SVR patients2022
- Author(s)
  Le Thi Thanh Thuy, Minh Phuong Dong, Hoang Hai, Vu Ngoc Hieu, Dinh Viet Hoang, Sawako Uchida-Kobayashi, Masaru Enomoto, Akihiro Tamori and Norifumi Kawada
- Organizer
  Annual Meeting of American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Cytoglobin, Neuroglobin, Myoglobin, but not Hemoglobin Exhibited Anti-Fibrotic Properties In Vitro and In Vivo2022
- Author(s)
  Le Thi Thanh Thuy, Vu Ngoc Hieu, Hoang Hai, Dinh Viet Hoang, and Norifumi Kawada
- Organizer
  the 58th Annual Meeting of the Japan Society of Hepatology
- Data Source
  KAKENHI-PROJECT-23K24322
[Presentation] Emerged NS5A RAS was associated with clinical course, and was not continuously predominant after DAA failure2017
- Author(s)
  Hoang Hai、田守昭博、河田則文
- Organizer
  第53回日本肝臓学会総会ワーショップ
- Data Source
  KAKENHI-PROJECT-15K09019
[Presentation] The MICA but not the DEPDC5, PNPLA3 and HCP5 polymorphism is associated with chronic hepatitis C-related hepatocellular carcinoma.2015
- Author(s)
  Hoang Hai
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  鶴屋ホール (熊本県・熊本市)
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26860522
[Presentation] MICA SNP, but not DEPDC5, PNPLA3 and HCP5 SNPs, is associated with chronic hepatitis C-related hepatocellular carcinoma2015
- Author(s)
  Hoang Hai, Akihiro Tamori, Kanako Yoshida, Atsushi Hagihara, Etsushi Kawamura, Sawako K. Uchida, Hiroyasu Morikawa, Masaru Enomoto, Yoshiki Murakami, Thuy T. Le, Norifumi Kawada.
- Organizer
  AASLD Annual Meeting.
- Place of Presentation
  サンフランシスコ(アメリカ合衆国)
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860522
[]

1. KAWADA Norifumi (30271191)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
2. LE THITHANHTHUY (10572175)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TAMORI Akihiro (30291595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 村上善基 (00397556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 榎本大 (20423874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 大藤さとこ (70433290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 久保正二 (80221224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松原三佐子 (00635120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. LE Thuy

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results
10. 松原三佐子(佐藤三佐子)

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 松原勤

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 及川大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 池田一雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 宇留島隼人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hoang Hai Ｈｏａｎｇ Ｈａｉ

HOANG HAI ホアン ハイ

HOANG Hai ホアン ハイ

Research Projects

Research Products

Co-Researchers

肝細胞のがん化における細胞間相互作用を介した星細胞の役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cytoglobin (CYGB)-overexpression and targeted demethylation of CYGB promoter impair liver and pancreatic tumor growthPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Hepatic pathology of patients achieved sustained hepatitis C viral response

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on miRNA expression and single nucleotide polymorphisms in hepatocellular carcinoma after HCV eradicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Liver Pathophysiology: Therapies and Antioxidants2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40?CD40L Linkage2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased spine bone density in patients with chronic hepatitis B switched to tenofovir alafenamide: A prospective, multinational study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nitric Oxide Derived from Cytoglobin-Deficient Hepatic Stellate Cells Causes Suppression of Cytochrome c Oxidase Activity in Hepatocytes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Soluble Immune Checkpoint Protein CD27 Is a Novel Prognostic Biomarker of Hepatocellular Carcinoma Development in Hepatitis C Virus?Sustained Virological Response Patients2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cytoglobin attenuates pancreatic cancer growth via scavenging reactive oxygen species2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cancer cells produce liver metastasis via gap formation in sinusoidal endothelial cells through proinflammatory paracrine mechanisms.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Outcomes for Cirrhotic Patients with Hepatitis C Virus 1b Treated with Asunaprevir and Daclatasvir Combination2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathophysiological role of cytoglobin, the fourth globin in mammals, in liver diseases.2016

Author(s)

Journal Title

Data Source

[Presentation] Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression.2024

Author(s)

Organizer

Data Source

[Presentation] Cell-cell interaction of LSECs-HSCs in the microenvironment of Diethyl nitrosamine treated Cytoglobin Knock-out mice.2024

Author(s)

Hoang Hai ＨｏａｎｇＨａｉ

HOANG HAI ホアンハイ

HOANG Hai ホアンハイ