ONISHI AKIRA 大西輝

… Alternative Names

Onishi Akira 大西輝

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Researcher Number	60634269
Other IDs
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都大学, 医学研究科, 特定講師 2018 – 2020: 神戸大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 58010:Medical management and medical sociology-related / Basic Section 54020:Connective tissue disease and allergy-related Except Principal Investigator Basic Section 58010:Medical management and medical sociology-related / Basic Section 58060:Clinical nursing-related / Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator 関節リウマチ / 合併症 / コホート研究 / NDB / 多施設共同レジストリー / 単施設コホート研究 / レセプトデータベース / メタ疫学研究 / メタ疫学 / 遺伝子一塩基多型 / 予測モデル / メトトレキサート / 薬剤代謝関連遺伝子一塩基多型 … More Except Principal Investigator … More 腸内細菌叢 / SLE / カヘキシア / フレイル / サルコペニア / QOL / 主観的幸福度 / 関節リウマチ / 薬物体内動態 / 質量分析 / バイオトランスフォーメーション / 抗体医薬品 / エビデンスプラクティスギャップ / リウマチ膠原病 / レセプトデータ / 病名検証研究 Less

保険ビッグデータを用いたエビデンスプラクティスギャップの測定と診療の質の向上
- Principal Investigator
  
  佐田憲映
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Kochi University
Analysis of biotransformation in therapeutic antibody
- Principal Investigator
  
  米澤淳
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Keio University
全身性エリテマトーデス患者におけるサルコペニア有病割合と関連因子に関する研究
- Principal Investigator
  
  鳥井美江
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Kyoto University
NDB・多施設レジストリー・単施設コホートの融合による関節リウマチの合併症の解明Principal Investigator
- Principal Investigator
  
  大西輝
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Kyoto University
The fluctuation in subjective well-being of patients with early rheumatoid arthritis
- Principal Investigator
  
  蔭山豪一
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Hyogo Prefectural Amagasaki General Medical Center
Development of personalized medicine for rheumatoid arthritis by integrating different research levelsPrincipal Investigator
- Principal Investigator
  
  Onishi Akira
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyoto University
  Kobe University

All 2024 2023 2019 2018

All Journal Article Presentation

[Journal Article] Predictive value of baseline concomitant glucocorticoid for abatacept-mediated long-term inhibition of radiographic progression: insights from the KURAMA cohort.2024
- Author(s)
  Kosaku Murakami; Ryu Watanabe; Toshimitsu Fujisaki; Hiromu Ito; Koichi Murata; Wataru Yamamoto; Takayuki Fujii; Hideo Onizawa; Akira Onishi; Masao Tanaka; Motomu Hashimoto; Akio Morinobu
- Journal Title
  
  Immunological medicine
  
  Volume: 47 Issue: 1 Pages: 45-51
- DOI
  10.1080/25785826.2023.2265148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-21K09298
[Journal Article] Comparison of safety and effectiveness between etanercept biosimilar LBEC0101 and reference in patients with rheumatoid arthritis in real-world data using the KURAMA cohort.2024
- Author(s)
  Tomoya Kawakami; Sho Masui; Akira Onishi; Hideo Onizawa; Takayuki Fujii; Kosaku Murakami; Koichi Murata; Masao Tanaka; Takashi Shimada; Shunsaku Nakagawa; Shuichi Matsuda; Akio Morinobu; Tomohiro Terada; Atsushi Yonezawa
- Journal Title
  
  Modern rheumatology
  
  Volume: - Issue: 6 Pages: 1135-1141
- DOI
  10.1093/mr/roae018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-23K27340
[Journal Article] Association of large joint involvement at the start of biological disease-modifying antirheumatic drugs and Janus kinase inhibitors with disease activity and drug retention in patients with rheumatoid arthritis: The ANSWER cohort study.2024
- Author(s)
  Iku Shirasugi; Akira Onishi; Keisuke Nishimura; Wataru Yamamoto; Kosaku Murakami; Hideo Onizawa; Yuichi Maeda; Kosuke Ebina; Yonsu Son; Hideki Amuro; Masaki Katayama; Ryota Hara; Koji Nagai; Yuri Hiramatsu; Motomu Hashimoto; Tadashi Okano; Toshihisa Maeda; Shinya Hayashi; Sho Sendo; Sadao Jinno; Yuzuru Yamamoto; Hirota
- Journal Title
  
  International journal of rheumatic diseases
  
  Volume: 27 Issue: 3
- DOI
  10.1111/1756-185x.15097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-23K08651
[Journal Article] Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis.2024
- Author(s)
  Shintaro Honda; Koichi Murata; Shunsuke Fujibayashi; Bungo Otsuki; Takayoshi Shimizu; Takayuki Fujii; Yaichiro Okuzu; Toshiyuki Kawai; Yutaka Kuroda; Akira Onishi; Kosaku Murakami; Hideo Onizawa; Masao Tanaka; Akio Morinobu; Shuichi Matsuda
- Journal Title
  
  Journal of neurosurgery. Spine
  
  Volume: - Issue: 1 Pages: 1-9
- DOI
  10.3171/2024.1.spine231199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414
[Journal Article] Comparison of retention of biologics in Japanese patients with elderly-onset rheumatoid arthritis-the ANSWER cohort study.2024
- Author(s)
  Sadao Jinno; Akira Onishi; Shuhei Hattori; Maureen Dubreuil; Yo Ueda; Keisuke Nishimura; Takaichi Okano; Hirotaka Yamada; Wataru Yamamoto; Koichi Murata; Hideo Onizawa; Kosuke Ebina; Yuichi Maeda; Yonsu Son; Hideki Amuro; Ryota Hara; Kenichiro Hata; Hideyuki Shiba; Masaki Katayama; Ryu Watanabe; Motomu Hashimoto; Jun S
- Journal Title
  
  Rheumatology (Oxford, England)
  
  Volume: - Issue: 2 Pages: 509-516
- DOI
  10.1093/rheumatology/keae081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-23K08651
[Journal Article] Avacopan's potential to decrease MPO-ANCA titres concurrent with ameliorated activity in ANCA-associated vasculitis.2024
- Author(s)
  Tomoki Taniguchi; Ryosuke Hiwa; Mikihito Shoji; Eriho Yamaguchi; Mirei Shirakashi; Hideo Onizawa; Hideaki Tsuji; Koji Kitagori; Ran Nakashima; Shuji Akizuki; Akira Onishi; Hajime Yoshifuji; Masao Tanaka; Akio Morinobu
- Journal Title
  
  Modern rheumatology case reports
  
  Volume: - Issue: 2 Pages: 314-317
- DOI
  10.1093/mrcr/rxae016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414
[Journal Article] Management and treatment outcomes of rheumatoid arthritis in the era of biologic and targeted synthetic therapies: evaluation of 10-year data from the KURAMA cohort.2024
- Author(s)
  Takayuki Fujii; Koichi Murata; Hideo Onizawa; Akira Onishi; Masao Tanaka; Kosaku Murakami; Kohei Nishitani; Moritoshi Furu; Ryu Watanabe; Motomu Hashimoto; Hiromu Ito; Takao Fujii; Tsuneyo Mimori; Akio Morinobu; Shuichi Matsuda
- Journal Title
  
  Arthritis research & therapy
  
  Volume: 26 Issue: 1 Pages: 16-16
- DOI
  10.1186/s13075-023-03251-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-22K16359
[Journal Article] A case of?atypical IgG4-related disease presenting hypereosinophilia, polyneuropathy, and?liver dysfunction.2023
- Author(s)
  Hiroki Mukoyama; Kosaku Murakami; Hideo Onizawa; Mirei Shirakashi; Ryosuke Hiwa; Hideaki Tsuji; Koji Kitagori; Shuji Akizuki; Ran Nakashima; Akira Onishi; Hajime Yoshifuji; Masao Tanaka; Akio Morinobu
- Journal Title
  
  Modern rheumatology case reports
  
  Volume: 8 Issue: 1 Pages: 172-177
- DOI
  10.1093/mrcr/rxad053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414
[Journal Article] Comparative effectiveness of biological disease-modifying antirheumatic drugs and Janus kinase inhibitor monotherapy in rheumatoid arthritis.2023
- Author(s)
  Akira Onishi; Hirotaka Yamada; Wataru Yamamoto; Ryu Watanabe; Ryota Hara; Masaki Katayama; Yasutaka Okita; Yuichi Maeda; Hideki Amuro; Yonsu Son; Ayaka Yoshikawa; Kenichiro Hata; Motomu Hashimoto; Jun Saegusa; Akio Morinobu
- Journal Title
  
  Rheumatology (Oxford, England)
  
  Volume: - Issue: 11 Pages: 3065-3073
- DOI
  10.1093/rheumatology/kead620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414
[Journal Article] Pathogenicity of IgG-Fc desialylation and its association with Th17 cells in an animal model of systemic lupus erythematosus.2023
- Author(s)
  Yuri Nishida; Mirei Shirakashi; Noritaka Hashii; Ran Nakashima; Yoichi Nakayama; Masao Katsushima; Ryu Watanabe; Hideo Onizawa; Ryosuke Hiwa; Hideaki Tsuji; Koji Kitagori; Shuji Akizuki; Akira Onishi; Kosaku Murakami; Hajime Yoshifuji; Masao Tanaka; Tatsuaki Tsuruyama; Akio Morinobu; Motomu Hashimoto
- Journal Title
  
  Modern rheumatology
  
  Volume: 34 Issue: 3 Pages: 523-529
- DOI
  10.1093/mr/road054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-22K20770
[Journal Article] POS0241?MONOCYTE-DERIVED TRANSCRIPTOMES EXPLAIN THE INEFFECTIVENESS OF ABATACEPT IN RHEUMATOID ARTHRITIS2023
- Author(s)
  T. Iwasaki; R. Watanabe; H. Ito; T. Fujii; K. Ohmura; H. Yoshitomi; K. Murata; K. Murakami; A. Onishi; M. Tanaka; S. Matsuda; F. Matsuda; A. Morinobu; M. Hashimoto
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 82 Pages: 353-354
- DOI
  10.1136/annrheumdis-2023-eular.970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414
[Journal Article] Efficacy of personalized exercise program on physical function in elderly patients with rheumatoid arthritis at high risk for sarcopenia: study protocol for a randomized controlled trial2023
- Author(s)
  Akira Onishi; Mie Torii; Yu Hidaka; Ryuji Uozumi; Yohei Oshima; Hiroki Tanaka; Hideo Onizawa; Takayuki Fujii; Koichi Murata; Kosaku Murakami; Masao Tanaka; Shuichi Matsuda; Akio Morinobu; Hidenori Arai; Motomu Hashimoto
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 24 Issue: 1 Pages: 280-280
- DOI
  10.1186/s12891-023-06185-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-21H02834, KAKENHI-PROJECT-23H05378
[Journal Article] Twenty-year follow-up of promising clinical studies reported in highly circulated newspapers: a meta-epidemiological study.2023
- Author(s)
  Aran Tajika; Yasushi Tsujimoto; Akira Onishi; Yusuke Tsutsumi; Satoshi Funada; Yusuke Ogawa; Nozomi Takeshima; Yu Hayasaka; Naotsugu Iwakami; Toshi A Furukawa
- Journal Title
  
  BMJ health & care informatics
  
  Volume: 30 Issue: 1 Pages: e100768-e100768
- DOI
  10.1136/bmjhci-2023-100768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414
[Journal Article] Trends of disease activity in Japanese patients over 75 years with rheumatoid arthritis from 2014 to 2021- the ANSWER cohort study.2023
- Author(s)
  Hirotaka Yamada; Sadao Jinno; Toshihisa Maeda; Shinya Hayashi; Wataru Yamamoto; Akira Onishi; Hideo Onizawa; Tohru Takeuchi; Yuri Hiramatsu; Yasutaka Okita; Kosuke Ebina; Yonsu Son; Naofumi Yoshida; Ryu Watanabe; Ryota Hara; Mai Yamashita; Yoko Nose; Yuzuru Yamamoto; Takaichi Okano; Keisuke Nishimura; Yo Ueda; Sho Send
- Journal Title
  
  Rheumatology (Oxford, England)
  
  Volume: - Issue: 8 Pages: 2147-2151
- DOI
  10.1093/rheumatology/kead539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-23K08651
[Journal Article] Prognostic Factors Affecting Death in Patients with Rheumatoid Arthritis Complicated by Pneumocystis jirovecii Pneumonia and One-Year Clinical Course: The ANSWER Cohort Study.2023
- Author(s)
  Hideyuki Shiba; Takuya Kotani; Koji Nagai; Kenichiro Hata; Wataru Yamamoto; Ayaka Yoshikawa; Yumiko Wada; Yuri Hiramatsu; Hidehiko Makino; Yo Ueda; Akira Onishi; Koichi Murata; Hideki Amuro; Yonsu Son; Ryota Hara; Toru Hirano; Kosuke Ebina; Masaki Katayama; Motomu Hashimoto; Tohru Takeuchi
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 24 Issue: 8 Pages: 7399-7399
- DOI
  10.3390/ijms24087399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-21K09298
[Journal Article] IL-6 inhibitors and JAK inhibitors as favourable treatment options for patients with anaemia and rheumatoid arthritis: ANSWER cohort study.2023
- Author(s)
  Yoichi Nakayama; Ryu Watanabe; Wataru Yamamoto; Kosuke Ebina; Toru Hirano; Takuya Kotani; Hideyuki Shiba; Masaki Katayama; Yonsu Son; Hideki Amuro; Akira Onishi; Sadao Jinno; Ryota Hara; Kosaku Murakami; Koichi Murata; Hiromu Ito; Masao Tanaka; Shuichi Matsuda; Akio Morinobu; Motomu Hashimoto
- Journal Title
  
  Rheumatology (Oxford, England)
  
  Volume: 63 Issue: 2 Pages: 349-357
- DOI
  10.1093/rheumatology/kead299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10414, KAKENHI-PROJECT-23K08651
[Journal Article] Genetic and clinical prediction models for the efficacy and hepatotoxicity of methotrexate in patients with rheumatoid arthritis: a multicenter cohort study2019
- Author(s)
  Onishi Akira、Kamitsuji Shigeo、Nishida Miwa、Uemura Yuko、Takahashi Miho、Saito Toshiharu、Yoshida Yuichiro、Kobayashi Masaki、Kawate Mizuho、Nishimura Keisuke、Misaki Kenta、Nobuhara Yumiko、Nakazawa Takashi、Hatachi Saori、Tsuji Goh、Morinobu Akio、Kumagai Shunichi
- Journal Title
  
  The Pharmacogenomics Journal
  
  Volume: - Issue: 3 Pages: 433-442
- DOI
  10.1038/s41397-019-0134-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16150, KAKENHI-PROJECT-16K19599
[Journal Article] 関節リウマチにおけるゲノム情報に基づくメトトレキサートの個別改良の可能性2019
- Author(s)
  大西輝、熊谷俊一
- Journal Title
  
  Precision Medicine
  
  Volume: 2 Pages: 72-76
- Data Source
  KAKENHI-PROJECT-18K16150
[Journal Article] 関節リウマチにおけるファーマコジェノミクスによるMTXの反応性、副作用予測2019
- Author(s)
  大西輝、熊谷俊一
- Journal Title
  
  Precision Medicine
  
  Volume: 1 Pages: 49-53
- Data Source
  KAKENHI-PROJECT-18K16150
[Presentation] The genetic and clinical prediction models for efficacy and hepatotoxicity of methotrexate in patients with rheumatoid arthritis2018
- Author(s)
  A. Onishi* 1, M. Nishida2, M. Takahashi3, Y. Yoshida4, M. Kobayashi4, S. Kamitsuji5, M. Kawate4, K. Nishimura6, K. Misaki7
- Organizer
  EULAR congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16150

1. 森信暁雄 (10294216)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 佐田憲映 (70423308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 宮脇義亜 (10761116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 木田節 (20848501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 下島恭弘 (50436896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 柳井亮 (50621166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 一瀬邦弘 (60437895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 吉見竜介 (70585265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 米澤淳 (90452341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中川俊作 (50721916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 蔭山豪一 (80631621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 三枝淳 (20514970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 籏智さおり (70414117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 西村啓佑 (20771497)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 脇大輔 (00914243)

# of Collaborated Projects: 1 results

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16. 鳥井美江 (60615285)

# of Collaborated Projects: 1 results

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17. 任和子 (40243084)

# of Collaborated Projects: 1 results

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18. 荒井秀典 (60232021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 板谷崇央 (70963536)

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20. 木下彩栄 (80321610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ONISHI AKIRA 大西 輝

Onishi Akira 大西 輝

Research Projects

Research Products

Co-Researchers

保険ビッグデータを用いたエビデンスプラクティスギャップの測定と診療の質の向上

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of biotransformation in therapeutic antibody

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

全身性エリテマトーデス患者におけるサルコペニア有病割合と関連因子に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

NDB・多施設レジストリー・単施設コホートの融合による関節リウマチの合併症の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The fluctuation in subjective well-being of patients with early rheumatoid arthritis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of personalized medicine for rheumatoid arthritis by integrating different research levelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Predictive value of baseline concomitant glucocorticoid for abatacept-mediated long-term inhibition of radiographic progression: insights from the KURAMA cohort.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of safety and effectiveness between etanercept biosimilar LBEC0101 and reference in patients with rheumatoid arthritis in real-world data using the KURAMA cohort.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of large joint involvement at the start of biological disease-modifying antirheumatic drugs and Janus kinase inhibitors with disease activity and drug retention in patients with rheumatoid arthritis: The ANSWER cohort study.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of high disease activity on spinal sagittal malalignment in patients with rheumatoid arthritis.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of retention of biologics in Japanese patients with elderly-onset rheumatoid arthritis-the ANSWER cohort study.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Avacopan's potential to decrease MPO-ANCA titres concurrent with ameliorated activity in ANCA-associated vasculitis.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Management and treatment outcomes of rheumatoid arthritis in the era of biologic and targeted synthetic therapies: evaluation of 10-year data from the KURAMA cohort.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of?atypical IgG4-related disease presenting hypereosinophilia, polyneuropathy, and?liver dysfunction.2023

Author(s)

Journal Title

DOI

ONISHI AKIRA 大西輝

Onishi Akira 大西輝