Kaihara Keiko 貝原恵子

Researcher Number	60638641
Other IDs
Affiliation (Current)	2022: 岡山大学, 医学部, 技術専門職員
Affiliation (based on the past Project Information) *help	2017 – 2021: 岡山大学, 医学部, 技術専門職員
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering / Basic Section 90110:Biomedical engineering-related Except Principal Investigator Basic Section 55030:Cardiovascular surgery-related / Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator メカノトランスダクション / 心不全 / 活性酸素（ROS） / NOX4 / NADPH oxidase 4 / 活性酸素（ROS) / 単離心筋細胞 / 圧負荷 / NADPH oxidase 4（NOX4) / 活性酸素( ROS ) … More / 生理学 / 循環器・高血圧 / 生理活性 / NADPHオキシダーゼ（NOX）4 / 活性酸素 … More Except Principal Investigator ヒト単離心筋細胞 / カーボンファイバー / 活性酸素 / 機械的負荷 Less

Force-Length Relationによる単離ヒト心筋細胞の機能評価
- Principal Investigator
  
  小松弘明
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Okayama University
心筋機械感受性制御におけるROSシグナリングの役割とその心不全治療への展開
- Principal Investigator
  
  入部玄太郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Asahikawa Medical College
Investigation of NOX4-mediated mechanotransduction in mechanically-induced cardiac failurePrincipal Investigator
- Principal Investigator
  
  貝原恵子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Okayama University
Physiological and pathophysiological role of NOX4 in cardiac mechano-transductionPrincipal Investigator
- Principal Investigator
  
  Kaihara Keiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Okayama University

All 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Ischemia Enhances the Acute Stretch-Induced Increase in Calcium Spark Rate in Ventricular Myocytes2020
- Author(s)
  Breanne A. Cameron, Hiroaki Kai, Keiko Kaihara, Gentaro Iribe and T. Alexander Quinn
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 11 Pages: 289-298
- DOI
  10.3389/fphys.2020.00289
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01359
[Journal Article] Mechano-sensitivity of mitochondrial function in mouse cardiac myocytes.2017
- Author(s)
  Iribe Gentaro、Kaihara Keiko、Yamaguchi Yohei、Nakaya Michio、Inoue Ryuji、Naruse Keiji
- Journal Title
  
  Progress in Biophysics and Molecular Biology
  
  Volume: 130 Pages: 315-322
- DOI
  10.1016/j.pbiomolbio.2017.05.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01359, KAKENHI-PUBLICLY-17H05510, KAKENHI-PROJECT-26220203, KAKENHI-PROJECT-15H04678, KAKENHI-PROJECT-17H03984
[Presentation] Effects of NOX4-induced ROS on single cell mechanics in mouse ventricular cardiomyocytes.2021
- Author(s)
  Keiko Kaihara, Keiji Naruse, Gentaro Iribe
- Organizer
  第126回日本解剖学会総会・全国学術集会 / 第98回日本生理学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-20K12598
[Presentation] Effects of NADPH oxidase (NOX) 4 on single cell mechanics in mouse ventricular cardiomyocytes.2020
- Author(s)
  貝原恵子、成瀬恵治、入部玄太郎
- Organizer
  第97回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K01359
[Presentation] Involvement of myocardial acute stretch-induced ROS production in pressure overload-induced contractile dysfunction in mouse hearts2020
- Author(s)
  Keiko Kaihara, Keiji Naruse, Gentaro Iribe
- Organizer
  第59回日本生体医工学会大会
- Data Source
  KAKENHI-PROJECT-20K12598
[Presentation] マウス心筋の伸展誘発性活性酸素産生およびミトコンドリア過分極におけるパネキシンヘミチャネルの役割2019
- Author(s)
  桂大輔、貝原恵子、赤嶺透子、成瀬恵治、入部玄太郎
- Organizer
  第71回　日本生理学会中国四国地方会
- Data Source
  KAKENHI-PROJECT-17K01359
[Presentation] 心筋バイオメカニクス制御におけるプリン作動性シグナリングの役割2019
- Author(s)
  赤嶺透子、貝原恵子、桂大輔、成瀬恵治、入部玄太郎
- Organizer
  第42回　日本生体医工学会中国四国支部大会
- Data Source
  KAKENHI-PROJECT-17K01359
[Presentation] Role of pannexin hemichannel on stretch-induced mitochondrial hyperpolarization in cardiomyocytes2019
- Author(s)
  Daisuke Katsura, Gentaro Iribe, Keiko Kaihara, Keiji Naruse.
- Organizer
  9th FAOPS CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01359
[Presentation] Effects of stretch-induced reactive oxygen species on single cell mechanics in mouse ventricular cardiomyocytes.2018
- Author(s)
  Keiko Kaihara, Gentaro Iribe ,Yohei Hayama, Hiroaki Kai, Keiji Naruse
- Organizer
  第95回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K01359
[Presentation] Single cell mechanics effects of NADPH oxidase (NOX) 4 in mouse ventricular cardiomyocytes.2018
- Author(s)
  Keiko Kaihara, Gentaro Iribe, Hiroaki Kai, Keiji Naruse.
- Organizer
  第56回　生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K01359
[Presentation] Effects of stretch-induced reactive oxygen species on calcium handling in mouse ventricular cardiomyocytes2018
- Author(s)
  Hiroaki Kai, Gentaro Iribe, Keiko Kaihara, Yohei Yamaguchi, Keiji Naruse
- Organizer
  第95回　日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K01359

1. 入部玄太郎 (90284885)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. 小松弘明 (40894952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 小谷恭弘 (90534678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山口陽平 (40831912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 金子智之 (80638643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 成瀬恵治 (40252233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. NAKAYA Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 王英正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 井上隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kaihara Keiko 貝原 恵子

Research Projects

Research Products

Co-Researchers

Force-Length Relationによる単離ヒト心筋細胞の機能評価

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

心筋機械感受性制御におけるROSシグナリングの役割とその心不全治療への展開

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of NOX4-mediated mechanotransduction in mechanically-induced cardiac failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological and pathophysiological role of NOX4 in cardiac mechano-transductionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ischemia Enhances the Acute Stretch-Induced Increase in Calcium Spark Rate in Ventricular Myocytes2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechano-sensitivity of mitochondrial function in mouse cardiac myocytes.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Effects of NOX4-induced ROS on single cell mechanics in mouse ventricular cardiomyocytes.2021

Author(s)

Organizer

Data Source

[Presentation] Effects of NADPH oxidase (NOX) 4 on single cell mechanics in mouse ventricular cardiomyocytes.2020

Author(s)

Organizer

Data Source

[Presentation] Involvement of myocardial acute stretch-induced ROS production in pressure overload-induced contractile dysfunction in mouse hearts2020

Author(s)

Organizer

Data Source

[Presentation] マウス心筋の伸展誘発性活性酸素産生およびミトコンドリア過分極におけるパネキシンヘミチャネルの役割2019

Author(s)

Organizer

Data Source

[Presentation] 心筋バイオメカニクス制御におけるプリン作動性シグナリングの役割2019

Author(s)

Organizer

Data Source

[Presentation] Role of pannexin hemichannel on stretch-induced mitochondrial hyperpolarization in cardiomyocytes2019

Author(s)

Organizer

Data Source

[Presentation] Effects of stretch-induced reactive oxygen species on single cell mechanics in mouse ventricular cardiomyocytes.2018

Author(s)

Organizer

Data Source

[Presentation] Single cell mechanics effects of NADPH oxidase (NOX) 4 in mouse ventricular cardiomyocytes.2018

Author(s)

Organizer

Data Source

[Presentation] Effects of stretch-induced reactive oxygen species on calcium handling in mouse ventricular cardiomyocytes2018

Author(s)

Organizer

Data Source

Kaihara Keiko 貝原恵子