Niinuma Takeshi 新沼猛

… Alternative Names

Takeshi Niinuma 新沼猛

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Researcher Number	60708113
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 札幌医科大学, 医学部, 講師 2014 – 2020: 札幌医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56050:Otorhinolaryngology-related / Basic Section 50010:Tumor biology-related / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 消化器がん / noncoding RNA / エピジェネティクス / long noncoding RNA / lncRNA / 大腸癌 / 細胞周期 / ミトコンドリア / IFNシグナル / IFNシグナリング … More / 胃癌 / noncodingRNA / 転移 / 消化管がん / 大腸がん / colon cancer / GIST / 消化管間質腫瘍 … More Except Principal Investigator 大腸がん / 腫瘍微小環境 / がん免疫 / インターフェロン応答 / DOT1L / エピゲノム / ヒストン修飾 / 腫瘍免疫 / がん関連線維芽細胞 / short ORF / マイクロプロテイン / noncoding RNA / 浸潤 / 微小環境 / 腫瘍関連好中球 / マクロファージ / SAA1 / 早期大腸がん Less

Identification of colorectal cancer-associated microproteins translated from noncoding RNAs
- Principal Investigator
  
  北嶋洋志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Sapporo Medical University
細胞周期とミトコンドリア代謝を制御するlncRNAによる消化器がん促進機構の解明Principal Investigator
- Principal Investigator
  
  新沼猛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Elucidation of Molecular Mechanisms in the Tumor Microenvironment of Head and Neck Cancer and Its Application to Cancer Immunotherapy.
- Principal Investigator
  
  萬顕
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Sapporo Medical University
大腸低分化腺がんにおけるSAA1の分子機能解明と診断・治療への応用
- Principal Investigator
  
  青木敬則
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
DOT1L阻害によるインターフェロン応答の機序解明とがん免疫療法への応用
- Principal Investigator
  
  鈴木拓
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Sapporo Medical University
がん細胞のインターフェロンシグナルを制御する長鎖noncoding RNAの解析Principal Investigator
- Principal Investigator
  
  新沼猛
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Comprehensive analysis of epigenetic alteration and lncRNA involved to colon cancer developmentPrincipal Investigator
- Principal Investigator
  
  Niinuma Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Epigenetic dysregulation of noncoding RNAs in gastrointestinal cancer progressionPrincipal Investigator
- Principal Investigator
  
  Niinuma Takeshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Epigenetic regulation of noncoding RNA in gastrointestinal stromal tumorPrincipal Investigator
- Principal Investigator
  
  Takeshi Niinuma
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas2024
- Author(s)
  Aoki Hironori、Takasawa Akira、Yamamoto Eiichiro、Niinuma Takeshi、Yamano Hiro-o、Harada Taku、Kubo Toshiyuki、Yorozu Akira、Kitajima Hiroshi、Ishiguro Kazuya、Kai Masahiro、Katanuma Akio、Shinohara Toshiya、Nakase Hiroshi、Sugai Tamotsu、Osanai Makoto、Suzuki Hiromu
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 24 Issue: 1 Pages: 24-24
- DOI
  10.1186/s12876-024-03175-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07964, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-23K07420, KAKENHI-PROJECT-23K24186
[Journal Article] CXCL12 is expressed by skeletal muscle cells in tongue oral squamous cell carcinoma.2023
- Author(s)
  Yorozu A, Sekiguchi S, Takasawa A, Okazaki F, Niinuma T, Kitajima H, Yamamoto E, Kai M, Toyota M, Hatanaka Y, Nishiyama K, Ogi K, Dehari H, Obata K, Kurose M, Kondo A, Osanai M, Miyazaki A, Takano K, Suzuki H.
- Journal Title
  
  Cancer Med.
  
  Volume: 12 Issue: 5 Pages: 5953-5963
- DOI
  10.1002/cam4.5392
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-22K17188, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-23K24186, KAKENHI-PROJECT-22K09687, KAKENHI-PROJECT-23K06445
[Journal Article] Serum amyloid A1 recruits neutrophils to the invasive front of T1 colorectal cancers.2023
- Author(s)
  Yoshido A, Sudo G, Takasawa A, Aoki H, Kitajima H, Yamamoto E, Niinuma T, Harada T, Kubo T, Sasaki H, Ishiguro K, Yorozu A, Kai M, Katanuma A, Yamano HO, Osanai M, Nakase H, Suzuki H.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 38 Issue: 2 Pages: 301-310
- DOI
  10.1111/jgh.16055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07964, KAKENHI-PROJECT-21K15556, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-22K16001, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-20K07662, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-23K24186, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-23K07420
[Journal Article] TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells2023
- Author(s)
  Kitajima Hiroshi、Maruyama Reo、Niinuma Takeshi、Yamamoto Eiichiro、Takasawa Akira、Takasawa Kumi、Ishiguro Kazuya、Tsuyada Akihiro、Suzuki Ryo、Sudo Gota、Kubo Toshiyuki、Idogawa Masashi、Toyota Mutsumi、Yoshido Ayano、Kumegawa Kohei、Kai Masahiro、Tokino Takashi、Osanai Makoto、Nakase Hiroshi、Suzuki Hiromu
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 7 Pages: 424-424
- DOI
  10.1038/s41419-023-05953-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16001, KAKENHI-PROJECT-21K07130, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07173, KAKENHI-PROJECT-23K06426, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K24186
[Journal Article] ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma2023
- Author(s)
  Sekiguchi Shohei、Yorozu Akira、Okazaki Fumika、Niinuma Takeshi、Takasawa Akira、Yamamoto Eiichiro、Kitajima Hiroshi、Kubo Toshiyuki、Hatanaka Yui、Nishiyama Koyo、Ogi Kazuhiro、Kai Masahiro、Hirohashi Yoshihiko、Torigoe Toshihiko、Kojima Takashi、Osanai Makoto、Takano Kenichi、Miyazaki Akihiro、Suzuki Hiromu
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 17 Pages: 4303-4303
- DOI
  10.3390/cancers15174303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17188, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K09687, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-23K24186
[Journal Article] Genome-Wide Analysis of microRNA and mRNA Expression in Colorectal Intramucosal Neoplasia and Colorectal Cancer With a Microsatellite-Stable Phenotype Based on Adenoma-Carcinoma Sequences2022
- Author(s)
  Sugai Tamotsu、Osakabe Mitsumasa、Niinuma Takeshi、Sugimoto Ryo、Eizuka Makoto、Tanaka Yoshihito、Yanagawa Naoki、Otsuka Koki、Sasaki Akira、Matsumoto Takayuki、Suzuki Hiromu
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 12 Pages: 831100-831100
- DOI
  10.3389/fonc.2022.831100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-23K24186
[Journal Article] Comprehensive analyses of microRNA and mRNA expression in colorectal serrated lesions and colorectal cancer with a microsatellite instability phenotype2021
- Author(s)
  Sugai Tamotsu、Osakabe Mitsumasa、Niinuma Takeshi、Eizuka Makoto、Tanaka Yoshihito、Yamada Shun、Yanagawa Naoki、Otsuka Koki、Sasaki Akira、Matsumoto Takayuki、Suzuki Hiromu
- Journal Title
  
  Genes, Chromosomes and Cancer
  
  Volume: 61 Issue: 3 Pages: 161-171
- DOI
  10.1002/gcc.23016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-23K24186
[Journal Article] Evaluation of Urinary DNA Methylation as a Marker for Recurrent Bladder Cancer: A 2-Center Prospective Study.2018
- Author(s)
  Shindo T, Shimizu T, Nojima M, Niinuma T, Maruyama R, Kitajima H, Kai M, Itoh N, Suzuki H, Masumori N
- Journal Title
  
  Urology.
  
  Volume: 113 Pages: 71-78
- DOI
  10.1016/j.urology.2017.11.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19352
[Journal Article] Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer.2017
- Author(s)
  Aoki H, Yamamoto E, Takasawa A, Niinuma T, Yamano HO, Harada T, Matsushita HO, Yoshikawa K, Takagi R, Harada E, Tanaka Y, Yoshida Y, Aoyama T, Eizuka M, Yorozu A, Kitajima H, Kai M, Sawada N, Sugai T, Nakase H, Suzuki H.
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Issue: 4 Pages: 4707-4721
- DOI
  10.18632/oncotarget.23523
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-17K15956, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16K19352, KAKENHI-PROJECT-16K21250, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-15K08973
[Journal Article] Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.2017
- Author(s)
  Kai M, Yamamoto E, Sato A, Yamano HO, Niinuma T, Kitajima H, Harada T, Aoki H, Maruyama R, Toyota M, Hatahira T, Nakase H, Sugai T, Yamashita T, Toyota M, Suzuki H.
- Journal Title
  
  Mol Carcinog
  
  Volume: - Issue: 7 Pages: 1743-1752
- DOI
  10.1002/mc.22631
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18431, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16K19352, KAKENHI-PROJECT-15K08973
[Journal Article] Downregulation of miR-186 is associated with metastatic recurrence of gastrointestinal stromal tumors.2017
- Author(s)
  Niinuma T, Kai M, Kitajima H, Yamamoto E, Harada T, Maruyama R, Nobuoka T, Kanda T, Hasegawa T, Tokino T, Sugai T, Shimomura Y, Nakase H, Suzuki H
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Pages: 5703-5710
- DOI
  10.3892/ol.2017.6911
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16H05419, KAKENHI-PROJECT-16K15600, KAKENHI-PROJECT-16K19352, KAKENHI-PROJECT-15K08973
[Journal Article] Downregulation of miR-186 is associated with metastatic recurrence of gastrointestinal stromal tumors2017
- Author(s)
  Takeshi Niinuma
- Journal Title
  
  Oncolgy Letters
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19352
[Journal Article] A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors.2015
- Author(s)
  Isosaka M, Niinuma T, Nojima M, Kai M, Yamamoto E, Maruyama R, Nobuoka T, Nishida T, Kanda T, Taguchi T, Hasegawa T, Tokino T, Hirata K, Suzuki H, Shinomura Y
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 7 Pages: e0133754-e0133754
- DOI
  10.1371/journal.pone.0133754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08973, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-15K15584, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-26640110, KAKENHI-PROJECT-26860514
[Presentation] LINC02154は口腔扁平上皮がんにおいて細胞周期関連遺伝子とミトコンドリア関連遺伝子を制御する2023
- Author(s)
  新沼猛
- Organizer
  第34回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] LINC02154 regulates cell cycle- and mitochondria-related genes in head and neck squamous cell carcinoma2023
- Author(s)
  新沼猛
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] 多発性骨髄腫においてDOT1L阻害は自然免疫シグナルを活性化する．2023
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，塚原智英，粂川昴平，関口翔平，佐々木基，甲斐正広，仲瀬裕志，鈴木拓．
- Organizer
  第16回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 多発性骨髄腫においてDOT1L阻害は自然免疫シグナルを活性化し，免疫調整津薬の効果を増強する．2023
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，塚原智英，廣橋良彦，粂川昂平，関口翔平，佐々木基，甲斐正広，鳥越俊彦，仲瀬裕志，鈴木拓．
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 早期大腸がん浸潤先進部の分子解析．2023
- Author(s)
  須藤豪太，山本英一郎，青木敬則，高澤啓，吉戸文乃，新沼猛，久保俊之，原田拓，萬顕，北嶋洋志，甲斐正広，小山内誠，仲瀬裕志，鈴木拓．
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07964
[Presentation] SMOC1のダウンレギュレーションは大腸鋸歯状病変の進展と関連する．2023
- Author(s)
  青木敬則，高澤啓，山本英一郎，新沼猛，山野泰穂，原田拓，久保俊之，北嶋洋志，甲斐正広，仲瀬裕志，菅井有，小山内誠，鈴木拓．
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07964
[Presentation] DOT1L inhibition activates innate immune signaling in multiple myeloma.2023
- Author(s)
  Ishiguro K, Kitajima H, Niinuma T, Maruyama R, Tsukahara T, Hirohashi Y, Kumegawa K, Sekiguchi S, Sasaki S, Kai M, Torigoe T, Nakase H, Suzuki H.
- Organizer
  2nd JCA-AACR Precision Cancer Medicine International Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] DOT1L阻害は乳がん細胞のインターフェロンシグナルを活性化することで抗腫瘍効果を示す．2023
- Author(s)
  吉戸文乃，石黒一也，新沼猛，丸山玲緒，北嶋洋志，粂川昂平，甲斐正広，鈴木拓．
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 多発性骨髄腫においてDOT1L阻害は自然免疫シグナルを活性化する．2023
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，塚原智英，廣橋良彦，粂川昴平，関口翔平，吉戸文乃，甲斐正広，鳥越俊彦，仲瀬裕志，鈴木拓．
- Organizer
  第127回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 大腸鋸歯状病変のDNAメチル化は正常大腸粘膜の抑制的なヒストン修飾と相関する．2023
- Author(s)
  鈴木拓，山本英一郎，須藤豪太，青木敬則，久保俊之，佐々木基，新沼猛，北嶋洋志，甲斐正広，山野泰穂，仲瀬裕志，菅井有．
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07964
[Presentation] LINC02154 regulates cell cycle- and mitochondria-related genes in head and neck squamous cell carcinoma2023
- Author(s)
  新沼猛
- Organizer
  第46回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] 胃炎・胃がん関連長鎖non-coding RNAはストレス顆粒形成を促進してアポトーシスを抑制する2022
- Author(s)
  北嶋洋志，丸山玲緒，新沼猛，高澤啓，山本英一郎，石黒一也，吉戸文乃，甲斐正広，小山内誠，時野隆至，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] Identification and functional analysis of a novel head and neck squamous cell carcinoma-associated long non-coding RNA2022
- Author(s)
  新沼猛
- Organizer
  第81回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] 活性化マクロファージはIL-1β-SAA1 axisを介して早期大腸がんの浸潤を促進する．2022
- Author(s)
  須藤豪太，山本英一郎，青木敬則，高澤啓，吉戸文乃，新沼猛，久保俊之，原田拓，萬顕，北嶋洋志，甲斐正広，小山内誠，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07964
[Presentation] Serum amyloid A1は好中球をリクルートして早期大腸癌の浸潤を促進する2022
- Author(s)
  吉戸文乃，須藤豪太，高澤啓，北嶋洋志，山本英一郎，青木敬則，新沼猛，石黒一也，久保俊之，原田拓，甲斐正広，小山内誠，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] SMOC1の大腸腫瘍診断マーカーとしての臨床的有用性の検討．2022
- Author(s)
  青木敬則，高澤啓，山本英一郎，新沼猛，山野泰穂，北嶋洋志，甲斐正広，久保俊之，原田拓，小山内誠，仲瀬裕志，菅井有，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07964
[Presentation] 多発性骨髄腫においてDOT1L阻害は免疫シグナルを活性化する2022
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，粂川昴平，関口翔平，甲斐正広，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 新規口腔扁平上皮がん関連長鎖noncoding RNAの同定と機能解析2022
- Author(s)
  新沼猛
- Organizer
  第15回エピジェネティクス研究会総会
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] DOT1L阻害は乳がん細胞のインターフェロンシグナルを活性化する2022
- Author(s)
  鈴木拓，丸山玲緒，北嶋洋志，石黒一也，新沼猛，粂川昴平，吉戸文乃，甲斐正広，仲瀬裕志．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 活性化マクロファージはIL-1β-SAA1 axisを介して早期大腸がんの浸潤を促進する2022
- Author(s)
  須藤豪太，山本英一郎，青木敬則，高澤啓，吉戸文乃，新沼猛，久保俊之，原田拓，萬顕，北嶋洋志，甲斐正広，小山内誠，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] Serum amyloid A1は好中球をリクルートして早期大腸癌の浸潤を促進する．2022
- Author(s)
  吉戸文乃，須藤豪太，高澤啓，北嶋洋志，山本英一郎，青木敬則，新沼猛，石黒一也，久保俊之，原田拓，甲斐正広，小山内誠，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07964
[Presentation] DLEU1 promotes oral squamous cell carcinoma progression by activating interferon-stimulated genes2021
- Author(s)
  新沼猛
- Organizer
  第32回消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] Identification and functional analysis of a novel head and neck squamous cell carcinoma-associated long non-coding RNA2021
- Author(s)
  新沼猛
- Organizer
  第39回札幌国際癌シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] Identification and functional analysis of a novel head and neck squamous cell carcinoma-associated long non-coding RNA2021
- Author(s)
  新沼猛
- Organizer
  第80回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] DLEU1 regulates interferon-related genes and relates to OSCC progression2021
- Author(s)
  新沼猛
- Organizer
  第22回日本RNA学会総会
- Data Source
  KAKENHI-PROJECT-21K07945
[Presentation] 口腔がん悪性度に関与するDLEU1の作用機構の解明とその臨床応用2020
- Author(s)
  新沼猛
- Organizer
  第71回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-18K07977
[Presentation] Dysregulation of lncRNAs located at the HOXA locus in metastatic pancreatic ductal carcinoma2020
- Author(s)
  Takeshi Niinuma
- Organizer
  第79回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-18K07977
[Presentation] UHRF1 depletion and HDAC inhibition synergistically reactivate epigenetically silenced genes in colorectal cancer cells.2019
- Author(s)
  新沼　猛
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07977
[Presentation] UHRF1 depletion and HDAC inhibition synergistically reactivate epigenetically silenced genes in colorectal cancer cells2018
- Author(s)
  新沼　猛
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07977
[Presentation] 消化管間質腫瘍におけるエピジェネティック制御を受けるlncRNAの解析2017
- Author(s)
  新沼　猛　　北嶋　洋志　　甲斐　正広　　鈴木　拓
- Organizer
  第11回　日本エピジェネティクス研究会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19352
[Presentation] 消化管間質腫瘍においてエピジェネティックに制御される長鎖noncoding RNAの探索2017
- Author(s)
  新沼　猛　北嶋　洋志　山本　英一郎　甲斐　正広　仲瀬裕志　時野隆至　今井浩三　鈴木　拓
- Organizer
  第76回　日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19352
[Presentation] 消化管間質腫瘍の再発に関連するmicroRNAの解析2016
- Author(s)
  新沼　猛
- Organizer
  第10回日本エピジェネティクス研究会年会
- Place of Presentation
  大阪府豊中市　千里ライフサイエンスセンター
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K19352
[Presentation] 消化管間質腫瘍の再発に関連するmicroRNAの解析2016
- Author(s)
  新沼　猛
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市　パシフィコ横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19352
[Presentation] 消化管間質腫瘍の再発に関連するmicroRNAの解析2015
- Author(s)
  新沼　猛
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860514
[Presentation] 消化管間質腫瘍におけるmicroRNA遺伝子のエピジェネティックな制御機構2015
- Author(s)
  新沼　猛
- Organizer
  第9回日本エピジェネティクス研究会
- Place of Presentation
  学術総合センター一橋講堂（東京都千代田区）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26860514
[Presentation] 消化管間質腫瘍の再発に関連するmicroRNAの解析2014
- Author(s)
  新沼　猛
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26860514
[Presentation] 消化管間質腫瘍における microRNA 遺伝子のエピジェネティックな制御2014
- Author(s)
  新沼　猛
- Organizer
  日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26860514
[Presentation] 消化管間質腫瘍における microRNA 遺伝子のエピジェネティックな制御2014
- Author(s)
  新沼　猛
- Organizer
  日本エピジェネティクス研究会年会
- Place of Presentation
  東京
- Year and Date
  2014-05-27
- Data Source
  KAKENHI-PROJECT-26860514

1. Suzuki Hiromu (20381254)

# of Collaborated Projects: 5 results

# of Collaborated Products: 14 results
2. 北嶋洋志 (90777971)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
3. 高澤啓 (00593021)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. 青木敬則 (40749496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 山本英一郎 (60567915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. 萬顕 (20792120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 仲瀬裕志 (60362498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. 菅井有

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 原田拓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 時野隆至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 須藤豪太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 畠中柚衣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Niinuma Takeshi 新沼 猛

Takeshi Niinuma 新沼 猛

Research Projects

Research Products

Co-Researchers

Identification of colorectal cancer-associated microproteins translated from noncoding RNAs

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細胞周期とミトコンドリア代謝を制御するlncRNAによる消化器がん促進機構の解明Principal Investigator

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Elucidation of Molecular Mechanisms in the Tumor Microenvironment of Head and Neck Cancer and Its Application to Cancer Immunotherapy.

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大腸低分化腺がんにおけるSAA1の分子機能解明と診断・治療への応用

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DOT1L阻害によるインターフェロン応答の機序解明とがん免疫療法への応用

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がん細胞のインターフェロンシグナルを制御する長鎖noncoding RNAの解析Principal Investigator

Principal Investigator

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Comprehensive analysis of epigenetic alteration and lncRNA involved to colon cancer developmentPrincipal Investigator

Principal Investigator

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Epigenetic dysregulation of noncoding RNAs in gastrointestinal cancer progressionPrincipal Investigator

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Epigenetic regulation of noncoding RNA in gastrointestinal stromal tumorPrincipal Investigator

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[Journal Article] Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas2024

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[Journal Article] CXCL12 is expressed by skeletal muscle cells in tongue oral squamous cell carcinoma.2023

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[Journal Article] Serum amyloid A1 recruits neutrophils to the invasive front of T1 colorectal cancers.2023

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Data Source

[Journal Article] TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells2023

Author(s)

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Data Source

[Journal Article] ACLP Activates Cancer-Associated Fibroblasts and Inhibits CD8+ T-Cell Infiltration in Oral Squamous Cell Carcinoma2023

Niinuma Takeshi 新沼猛

Takeshi Niinuma 新沼猛