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HIGUCHI FUMIHIRO  樋口 文宏

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… Alternative Names

樋口 文宏  ヒグチ フミヒロ

HIGUCHI Fumihiro  樋口 文宏

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Researcher Number 60711249
Other IDs
Affiliation (Current) 2025: 山口大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help 2023: 山口大学, 医学部附属病院, 講師
2018: 山口大学, 医学部附属病院, 講師
2017: 山口大学, 大学院医学系研究科, 助教
2014 – 2016: 山口大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Psychiatric science
Except Principal Investigator
Basic Section 52030:Psychiatry-related / Psychiatric science
Keywords
Principal Investigator
うつ病 / うつ / ストレスレジリエンス / 遺伝子発現 / 動物モデル / マイクロRNA / ストレス / 神経可塑性 / 気分障害 / microRNA-124 … More
Except Principal Investigator
… More うつ病 / 光トポグラフィー / 前頭葉 / 情動調整障害 / フロー体験 / ニューロフィードバック / CaMKII / HDAC / ストレス脆弱性 / 神経ネットワーク / 遺伝子発現 / うつ / エピジェネティクス / ストレス Less
  • Research Projects

    (4 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (10 People)
  •  Development of a treatment for depression using frontal lobe neurofeedback with flow experience.

    • Principal Investigator
      松原 敏郎
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Yamaguchi University
  •  MicroRNA profiling in stress-resilient and stress-susceptible micePrincipal Investigator

    • Principal Investigator
      HIGUCHI Fumihiro
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Yamaguchi University
  •  Molecular and neural mechanisms of depression

    • Principal Investigator
      WATANABE Yoshifumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Yamaguchi University
  •  Hippocampal microRNA-124 enhances chronic stress resilience in micePrincipal Investigator

    • Principal Investigator
      HIGUCHI Fumihiro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Psychiatric science
    • Research Institution
      Yamaguchi University

All 2018 2017 2016 Other

All Journal Article Presentation

  • [Journal Article] Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression2018

    • Author(s)
      Yamagata Hirotaka、Uchida Shusaku、Matsuo Koji、Harada Kenichiro、Kobayashi Ayumi、Nakashima Mami、Higuchi Fumihiro、Watanuki Toshio、Matsubara Toshio、Watanabe Yoshifumi
    • Journal Title

      Journal of Affective Disorders

      Volume: 233 Pages: 79-85

    • DOI

      10.1016/j.jad.2017.08.057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09832, KAKENHI-PROJECT-16K10189, KAKENHI-PROJECT-17K16380
  • [Journal Article] Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior2016

    • Author(s)
      Naoko Abe-Higuchi, Shusaku Uchida, Hirotaka Yamagata, Fumihiro Higuchi, Teruyuki Hobara, Kumiko Hara, Ayumi Kobayashi, and Yoshifumi Watanabe
    • Journal Title

      Biological Psychiatry

      Volume: In press Issue: 11 Pages: 815-826

    • DOI

      10.1016/j.biopsych.2016.01.009

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25893152, KAKENHI-PROJECT-26670542, KAKENHI-PROJECT-26860481, KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-15K09807
  • [Journal Article] Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice.2016

    • Author(s)
      Higuchi F, Uchida S, Yamagata H, Abe-Higuchi N, Hobara T, Hara K, Kobayashi A, Shintaku T, Itoh Y, Suzuki T, Watanabe Y.
    • Journal Title

      J Neurosci.

      Volume: 36 Issue: 27 Pages: 7253-7267

    • DOI

      10.1523/jneurosci.0319-16.2016

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-16K10189
  • [Presentation] ストレス適応機構に対するヒストン脱アセチル化酵素の役割の解析2017

    • Author(s)
      樋口文宏
    • Organizer
      日本生物学的精神医学会
    • Data Source
      KAKENHI-PROJECT-17K16380
  • [Presentation] ストレス適応破綻からみたうつ病態における神経可塑性異常とその分子基盤2016

    • Author(s)
      内田周作、山形弘隆、芳原輝之、樋口文宏 、樋口尚子、 渡辺義文
    • Organizer
      第38回日本生物学的精神医学会 第59回日本神経化学会大会
    • Place of Presentation
      福岡国際会議場 (福岡県・福岡市)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-15H04895
  • [Presentation] Identification of biomarkers in blood in elder patients with early-onset major depressive disorder.2016

    • Author(s)
      6.Hirotaka Yamagata, Shuaku Uchida, Kenichiro Harada, Fumihiro Higuchi, Koji Matsuo, Shigeo Miyata, Masato Fukuda, Masahiko Mikuni, Yoshifumi Watanabe
    • Organizer
      Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (USA)
    • Year and Date
      2016-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04895
  • [Presentation] うつ病の発症脆弱性の分子機構を考える.2016

    • Author(s)
      3.渡辺義文, 内田周作, 山形弘隆, 樋口文宏
    • Organizer
      第38回日本生物学的精神医学会 第59回日本神経化学会大会
    • Place of Presentation
      福岡国際会議場 (福岡県・福岡市)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-15H04895
  • [Presentation] うつ病と神経細胞死2016

    • Author(s)
      4.山形弘隆, 内田周作, 樋口文宏, 渡邉義文
    • Organizer
      第38回日本生物学的精神医学会 第59回日本神経化学会大会
    • Place of Presentation
      福岡国際会議場 (福岡県・福岡市)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-15H04895
  • [Presentation] Hippocampal microRNA-124 enhances chronic stress resilience in mice2016

    • Author(s)
      樋口文宏、内田周作、山形弘隆、渡辺義文
    • Organizer
      第38回日本生物学的精神医学会・第59回日本神経化学会大会 合同年会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2016-09-08
    • Data Source
      KAKENHI-PROJECT-26860930
  • [Presentation] Hippocampal SIRT1 signaling mediates depression-related behacior in mice.2016

    • Author(s)
      1.Shusaku Uchida, Naoko Abe-Higuchi, Fumihiro Higuchi, Hirotaka Yamagata, Koji Matsuo, Yoshifumi Watanabe
    • Organizer
      Society of Biological Psychiatry 71st Annual meeting
    • Place of Presentation
      Atlanta Convention Center (USA)
    • Year and Date
      2016-05-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04895
  • [Presentation] うつ様行動と神経可塑性におけるmicroRNA-124とHDAC7の役割の解析

    • Author(s)
      樋口文宏、内田周作、山形弘隆、大朏孝治、芳原輝之、樋口尚子、柴田朋彦、渡邉義文
    • Organizer
      第36回生物学的精神医学会/第57回日本神経化学会大会
    • Place of Presentation
      奈良県文化会館
    • Year and Date
      2014-09-29 – 2014-10-01
    • Data Source
      KAKENHI-PROJECT-26860930
  • 1.  WATANABE Yoshifumi (90182964)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  内田 周作 (10403669)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 3.  山形 弘隆 (10549934)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 4.  松原 敏郎 (60526896)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  藤田 悠介 (40509527)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  原田 健一郎 (50761011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  中川 伸 (60360905)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  陳 冲 (70783067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  松尾 幸治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  樋口 尚子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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