HIGUCHI FUMIHIRO 樋口文宏

… Alternative Names

樋口文宏ヒグチフミヒロ

HIGUCHI Fumihiro 樋口文宏

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Researcher Number	60711249
Other IDs
Affiliation (Current)	2025: 山口大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2023: 山口大学, 医学部附属病院, 講師 2018: 山口大学, 医学部附属病院, 講師 2017: 山口大学, 大学院医学系研究科, 助教 2014 – 2016: 山口大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Psychiatric science Except Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science
Keywords	Principal Investigator うつ病 / うつ / ストレスレジリエンス / 遺伝子発現 / 動物モデル / マイクロRNA / ストレス / 神経可塑性 / 気分障害 / microRNA-124 … More Except Principal Investigator … More うつ病 / 光トポグラフィー / 前頭葉 / 情動調整障害 / フロー体験 / ニューロフィードバック / CaMKII / HDAC / ストレス脆弱性 / 神経ネットワーク / 遺伝子発現 / うつ / エピジェネティクス / ストレス Less

Development of a treatment for depression using frontal lobe neurofeedback with flow experience.
- Principal Investigator
  
  松原敏郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Yamaguchi University
MicroRNA profiling in stress-resilient and stress-susceptible micePrincipal Investigator
- Principal Investigator
  
  HIGUCHI Fumihiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Molecular and neural mechanisms of depression
- Principal Investigator
  
  WATANABE Yoshifumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University
Hippocampal microRNA-124 enhances chronic stress resilience in micePrincipal Investigator
- Principal Investigator
  
  HIGUCHI Fumihiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Yamaguchi University

All 2018 2017 2016 Other

All Journal Article Presentation

[Journal Article] Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression2018
- Author(s)
  Yamagata Hirotaka、Uchida Shusaku、Matsuo Koji、Harada Kenichiro、Kobayashi Ayumi、Nakashima Mami、Higuchi Fumihiro、Watanuki Toshio、Matsubara Toshio、Watanabe Yoshifumi
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 233 Pages: 79-85
- DOI
  10.1016/j.jad.2017.08.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09832, KAKENHI-PROJECT-16K10189, KAKENHI-PROJECT-17K16380
[Journal Article] Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior2016
- Author(s)
  Naoko Abe-Higuchi, Shusaku Uchida, Hirotaka Yamagata, Fumihiro Higuchi, Teruyuki Hobara, Kumiko Hara, Ayumi Kobayashi, and Yoshifumi Watanabe
- Journal Title
  
  Biological Psychiatry
  
  Volume: In press Issue: 11 Pages: 815-826
- DOI
  10.1016/j.biopsych.2016.01.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25893152, KAKENHI-PROJECT-26670542, KAKENHI-PROJECT-26860481, KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-15K09807
[Journal Article] Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice.2016
- Author(s)
  Higuchi F, Uchida S, Yamagata H, Abe-Higuchi N, Hobara T, Hara K, Kobayashi A, Shintaku T, Itoh Y, Suzuki T, Watanabe Y.
- Journal Title
  
  J Neurosci.
  
  Volume: 36 Issue: 27 Pages: 7253-7267
- DOI
  10.1523/jneurosci.0319-16.2016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04895, KAKENHI-PROJECT-16K10189
[Presentation] ストレス適応機構に対するヒストン脱アセチル化酵素の役割の解析2017
- Author(s)
  樋口文宏
- Organizer
  日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-17K16380
[Presentation] ストレス適応破綻からみたうつ病態における神経可塑性異常とその分子基盤2016
- Author(s)
  内田周作、山形弘隆、芳原輝之、樋口文宏、樋口尚子、渡辺義文
- Organizer
  第38回日本生物学的精神医学会第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] Identification of biomarkers in blood in elder patients with early-onset major depressive disorder.2016
- Author(s)
  6.Hirotaka Yamagata, Shuaku Uchida, Kenichiro Harada, Fumihiro Higuchi, Koji Matsuo, Shigeo Miyata, Masato Fukuda, Masahiko Mikuni, Yoshifumi Watanabe
- Organizer
  Society for Neuroscience
- Place of Presentation
  San Diego Convention Center (USA)
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] うつ病の発症脆弱性の分子機構を考える.2016
- Author(s)
  3.渡辺義文, 内田周作, 山形弘隆, 樋口文宏
- Organizer
  第38回日本生物学的精神医学会第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] うつ病と神経細胞死2016
- Author(s)
  4.山形弘隆, 内田周作, 樋口文宏, 渡邉義文
- Organizer
  第38回日本生物学的精神医学会第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場 (福岡県・福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] Hippocampal microRNA-124 enhances chronic stress resilience in mice2016
- Author(s)
  樋口文宏、内田周作、山形弘隆、渡辺義文
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26860930
[Presentation] Hippocampal SIRT1 signaling mediates depression-related behacior in mice.2016
- Author(s)
  1.Shusaku Uchida, Naoko Abe-Higuchi, Fumihiro Higuchi, Hirotaka Yamagata, Koji Matsuo, Yoshifumi Watanabe
- Organizer
  Society of Biological Psychiatry 71st Annual meeting
- Place of Presentation
  Atlanta Convention Center (USA)
- Year and Date
  2016-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04895
[Presentation] うつ様行動と神経可塑性におけるmicroRNA-124とHDAC7の役割の解析
- Author(s)
  樋口文宏、内田周作、山形弘隆、大朏孝治、芳原輝之、樋口尚子、柴田朋彦、渡邉義文
- Organizer
  第36回生物学的精神医学会/第57回日本神経化学会大会
- Place of Presentation
  奈良県文化会館
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-26860930

1. WATANABE Yoshifumi (90182964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 内田周作 (10403669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 山形弘隆 (10549934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 松原敏郎 (60526896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 藤田悠介 (40509527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 原田健一郎 (50761011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 中川伸 (60360905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 陳冲 (70783067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松尾幸治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 樋口尚子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIGUCHI FUMIHIRO 樋口 文宏

樋口 文宏 ヒグチ フミヒロ

HIGUCHI Fumihiro 樋口 文宏

Research Projects

Research Products

Co-Researchers

Development of a treatment for depression using frontal lobe neurofeedback with flow experience.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

MicroRNA profiling in stress-resilient and stress-susceptible micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular and neural mechanisms of depression

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hippocampal microRNA-124 enhances chronic stress resilience in micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Altered plasma protein glycosylation in a mouse model of depression and in patients with major depression2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hippocampal Sirtuin 1 Signaling Mediates Depression-like Behavior2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice.2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] ストレス適応機構に対するヒストン脱アセチル化酵素の役割の解析2017

Author(s)

Organizer

Data Source

[Presentation] ストレス適応破綻からみたうつ病態における神経可塑性異常とその分子基盤2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Identification of biomarkers in blood in elder patients with early-onset major depressive disorder.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] うつ病の発症脆弱性の分子機構を考える.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] うつ病と神経細胞死2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Hippocampal microRNA-124 enhances chronic stress resilience in mice2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Hippocampal SIRT1 signaling mediates depression-related behacior in mice.2016

HIGUCHI FUMIHIRO 樋口文宏

樋口文宏ヒグチフミヒロ

HIGUCHI Fumihiro 樋口文宏