MARUHAMA Kotaro 丸濱功太郎

Researcher Number	60712792
Affiliation (based on the past Project Information) *help	2016 – 2020: 岡山大学, 医歯薬学総合研究科, 助教 2013 – 2016: 岡山大学, 医歯(薬)学総合研究科, 助教
Review Section/Research Field	Principal Investigator Prosthodontics/ Dental materials science and Except Principal Investigator Biomedical engineering/Biomaterial science and engineering / Basic Section 57080:Social dentistry-related / Prosthodontics/ Dental materials science and
Keywords	Principal Investigator 神経障害性疼痛 / 三叉神経 / 神経伝達物質 / ボツリヌス毒素 / 歯学 / 脳・神経 / 解剖学 / 神経科学 / SNAP-25 / 知覚神経節 / 精製A型ボツリヌス毒素 / 軸索輸送 … More Except Principal Investigator … More 細菌 / 神経障害性疼痛 / ボツリヌス神経毒素 / 予防医学 / ポドプラニン研究 / マウス実験 / TLR阻害剤 / 疫学的メタ解析 / 複雑系 / 腸管免疫撹乱 / 歯周病 / TLR / フレイル / LPS / リン再吸収抑制ホルモン / アンジオテンシン変換酵素2 / Porphyromonas gingivalis / 歯周疾患 / ACE2 / SGLT2 / 白血球接着因子 / lipopolysaccharide / P. gingivalis / toll-like receptor / 歯周炎 / 糖尿病性腎症 / SNAREタンパク質 / SNAP-25 / 疼痛抑制 / fMRI / ボツリヌス毒素 / PET/CT / 咬合違和感 / 歯根膜感覚 Less

Study on epidemiological meta-analysis of diabetic nephropathy focusing on complex systems of periodontal disease and intestinal immune disturbance
- Principal Investigator
  
  SAWA Yoshihiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Okayama University
Preclinical study on botulinum toxin therapy in treatment for neuropathic pain
- Principal Investigator
  
  YAMAMOTO Yumiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Okayama University
Involvement of signal transduction by chemical synapse in neuropathic pain mechanisms.Principal Investigator
- Principal Investigator
  
  Maruhama Kotaro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Okayama University
Neural transmission mechanisms of tooth mechanical stimulation -Development of treatment for occlusal dysesthesia patients-
- Principal Investigator
  
  MATSUKA Yoshizo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  The University of Tokushima
Clarification of molecular mechanisms underlying the analgesic effect of botulinum toxin and applied study
- Principal Investigator
  
  YAMAMOTO YUMIKO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Okayama University
Analgesic mechanism of Botulinum toxin in neuropathic painPrincipal Investigator
- Principal Investigator
  
  MARUHAMA Kotaro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Prosthodontics/ Dental materials science and
- Research Institution
  Okayama University

All 2019 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Convergent nociceptive input to spinal dorsal horn neurons after peripheral nerve injury2015
- Author(s)
  Terayama R, Kishimoto N, Yamamoto Y, Maruhama K, Tsuchiya H, Mizutani M, Iida S, Sugimoto T
- Journal Title
  
  Neurochem Res
  
  Volume: 40 Issue: 3 Pages: 438-445
- DOI
  10.1007/s11064-014-1484-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592764, KAKENHI-PROJECT-25893140
[Journal Article] Cross-Excitation in Peripheral Sensory Ganglia Associated with Pain Transmission.2015
- Author(s)
  Omoto K, Maruhama K, Terayama R, Yamamoto Y, Matsushita O, Sugimoto T, Oguma K, Matsuka Y
- Journal Title
  
  Toxins (Basel)
  
  Volume: 7 Issue: 8 Pages: 2906-2917
- DOI
  10.3390/toxins7082906
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26350499, KAKENHI-PROJECT-26293412
[Journal Article] Basic research and clinical investigations of the neural basis of orofacial pain2015
- Author(s)
  Matsuka Y, Iwata K, Terayama R, Imamura Y, Maruhama K, Shinoda M, Tsuboi Y, Kondo M, Honda K, Katagiri A, Sugimoto T
- Journal Title
  
  J Oral Biosci
  
  Volume: 57 Issue: 1 Pages: 27-36
- DOI
  10.1016/j.job.2014.09.001
- NAID
  120006493387
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592764, KAKENHI-PROJECT-24593064, KAKENHI-PROJECT-15K11326, KAKENHI-PROJECT-26293412
[Journal Article] Assessment of intraoral mucosal pain induced by the application of capsaicin2014
- Author(s)
  Terayama R, Maruhama K, Tsuchiya H, Mizutani M, Iida S, Sugimoto T
- Journal Title
  
  Arch Oral Biol
  
  Volume: 59 Issue: 12 Pages: 1334-1341
- DOI
  10.1016/j.archoralbio.2014.08.008
- NAID
  120005477122
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592764, KAKENHI-PROJECT-25893140
[Presentation] ボツリヌス神経毒素の三叉神経節での作用機構の解析2019
- Author(s)
  山本由弥子、丸濱功太郎、松香芳三、美間健彦、後藤和義、Arief Waskitho、横田憲治、阪口義彦、松下治、小熊惠二
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-17K01358
[Presentation] 末梢神経損傷後の脊髄後角ニューロンの興奮性における時間空間的変化2016
- Author(s)
  寺山隆司，山本裕也，岸本宜子，田畑光康，丸濱功太郎，飯田征二，杉本朋貞
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-16K21187
[Presentation] 神経障害性疼痛における神経伝達物質遊離抑制と鎮痛効果2015
- Author(s)
  大本勝弘，丸濱功太郎，田中紗友里，大倉一夫，松香芳三
- Organizer
  補綴若手研究会
- Place of Presentation
  ニューアカオ（静岡県・熱海市）
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-26293412
[Presentation] Pain transmission within peripheral sensory ganglia2015
- Author(s)
  Omoto K, Maruhama K, Yamamoto Y, Sugimoto T, Matsushita O, Neubert JK, Matsuka Y
- Organizer
  Society for Neuroscience
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293412
[Presentation] Relationship between neurotransmitter release within sensory ganglia and pain transmission2015
- Author(s)
  Omoto K, Tanaka S, Suzuki Y, Okura K, Maruhama K, Sugimoto T, Matsuka Y
- Organizer
  . International Association for Dental Research
- Place of Presentation
  Boston, America
- Year and Date
  2015-03-13
- Data Source
  KAKENHI-PROJECT-26293412
[Presentation] The axonal transport and analgesic effect of newly developed Botulinum neurotoxin type A2014
- Author(s)
  Kotaro Maruhama, Yoshizo Matsuka, Yumiko Yamamoto, Ryuji Terayama, Tomosada Sugimoto
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25893140
[Presentation] Neural excitation with positron emission tomography after tooth mechanical stimulation2014
- Author(s)
  Omoto K, Maruhama K, Sugimoto T, Matsuka Y
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington DC, America
- Year and Date
  2014-11-18
- Data Source
  KAKENHI-PROJECT-26293412
[Presentation] 末梢知覚神経節における神経伝達物質遊離抑制と鎮痛効果2014
- Author(s)
  田中紗友里，大本勝弘，丸濱功太郎，杉本朋貞，松香芳三
- Organizer
  日本補綴歯科学会中国・四国、関西支部合同学術大会
- Place of Presentation
  倉敷芸文館（岡山県・倉敷市）
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-26293412
[Presentation] 末梢知覚神経節における神経伝達物質遊離抑制による情報伝達の変化2014
- Author(s)
  大本勝弘, 丸濱功太郎, 田中紗友里, 大倉一夫, 杉本朋貞, 松香芳三
- Organizer
  日本口腔顔面痛学会
- Place of Presentation
  東京医科歯科大学（東京都・文京区）
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-26293412
[Presentation] ボツリヌス毒素を利用した神経障害性疼痛治療
- Author(s)
  松香芳三，丸濱功太郎，山本由弥子，小熊惠二，松下治
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  岐阜
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26350499
[Presentation] Neural excitation with positron emission tomography after tooth mechanical stimulation
- Author(s)
  Katsuhiro Omoto, Kotaro Maruhama, Tomosada Sugimoto, Yoshizo Matsuka
- Organizer
  Society for Neuroscience 2014
- Place of Presentation
  Washington convention center
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25893140
[Presentation] 三叉神経におけるA型ボツリヌス神経毒素の局在と軸索輸送
- Author(s)
  山本由弥子，丸濱功太郎，松香芳三，美間健彦，後藤和義，横田憲治，松下治，小熊惠二
- Organizer
  第67回日本細菌学会中国・四国支部総会
- Place of Presentation
  徳島
- Year and Date
  2014-10-04 – 2014-10-05
- Data Source
  KAKENHI-PROJECT-26350499
[Presentation] Relationship Between Neurotransmitter release within sensory ganglia and pain transmission
- Author(s)
  K. Omoto, K. Maruhama, Y. Suzuki, K. Okura, Y. Matsuka
- Organizer
  IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Boston
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-25893140
[Presentation] 精製A型ボツリヌス毒素の軸索輸送と疼痛抑制効果
- Author(s)
  丸濱功太郎，松香芳三，山本由弥子，寺山隆司，杉本朋貞
- Organizer
  第37回日本神経科学大会 Neuroscience 2014
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-26350499
[Presentation] The axonal transport and analgesic effect of newly developed Botulinum neurotoxin type A
- Author(s)
  Kotaro Maruhama, Yoshizo Matsuka, Yumiko Yamamoto, Ryuji Terayama, Tomosada Sugimoto
- Organizer
  Neuroscience 2014
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25893140

1. MATSUKA Yoshizo (90243477)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
2. YAMAMOTO YUMIKO (20403496)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. MATSUSHITA Osamu (00209537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. SAWA Yoshihiko (70271666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 小川匠 (20267537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 小出隆規 (70322253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 加藤幸成 (00571811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 坂上竜資 (50215612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OGUMA Keiji

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. SUGIMOTO Tomosada

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 寺山隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

MARUHAMA Kotaro 丸濱 功太郎

Research Projects

Research Products

Co-Researchers

Study on epidemiological meta-analysis of diabetic nephropathy focusing on complex systems of periodontal disease and intestinal immune disturbance

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preclinical study on botulinum toxin therapy in treatment for neuropathic pain

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of signal transduction by chemical synapse in neuropathic pain mechanisms.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neural transmission mechanisms of tooth mechanical stimulation -Development of treatment for occlusal dysesthesia patients-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of molecular mechanisms underlying the analgesic effect of botulinum toxin and applied study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analgesic mechanism of Botulinum toxin in neuropathic painPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Convergent nociceptive input to spinal dorsal horn neurons after peripheral nerve injury2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cross-Excitation in Peripheral Sensory Ganglia Associated with Pain Transmission.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Basic research and clinical investigations of the neural basis of orofacial pain2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Assessment of intraoral mucosal pain induced by the application of capsaicin2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] ボツリヌス神経毒素の三叉神経節での作用機構の解析2019

Author(s)

Organizer

Data Source

[Presentation] 末梢神経損傷後の脊髄後角ニューロンの興奮性における時間空間的変化2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 神経障害性疼痛における神経伝達物質遊離抑制と鎮痛効果2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Pain transmission within peripheral sensory ganglia2015

Author(s)

MARUHAMA Kotaro 丸濱功太郎