TOKORO MIYUKI 所美雪 (馬渕美雪)

… Alternative Names

TOKORO(MABUCHI) MIYUKI 所美雪

馬渕美雪

MABUCHI MIYUKI 馬渕美雪

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Researcher Number	60714897
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 兵庫医科大学, 薬学部, 助教 2015 – 2019: 兵庫医療大学, 薬学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 37030:Chemical biology-related / Drug development chemistry Except Principal Investigator Basic Section 56010:Neurosurgery-related / Drug development chemistry
Keywords	Principal Investigator Rab / アフィニティ樹脂 / 低分子化合物 / アレルギー / 前立腺 / Cisplatin / 中皮腫 / 前立腺癌 / ＡＬＫＢＨ３ / ＰＣＡ－１ … More / MESO-4 / 悪性中皮腫 / 併用効果 / Docetaxel / 前立腺がん / 抗がん剤 / ALKBH3 / PCA-1 … More Except Principal Investigator 機械学習 / ビッグデータ / 代謝物 / ドラッグリポジショニング / 膠芽腫 / 前立腺がん / PCA-1阻害剤 / 経口剤 / xenograftモデル / 代謝安定性 / 前立腺癌 / 創薬化学 / PCA-1 / 抗がん剤 Less

臨床ビッグデータ情報と医薬品代謝物への構造変化を基軸した膠芽腫治療薬の創製
- Principal Investigator
  
  清水忠
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hyogo Medical University
Discovery of anti-allergic drugs regulating a novel target molecule, Rab, identified by affinity technology.Principal Investigator
- Principal Investigator
  
  TOKORO(MABUCHI) MIYUKI
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Hyogo Medical University
  Hyogo University of Health Sciences
Drug discovery research for clinical application of PCA-1 inhibitorsPrincipal Investigator
- Principal Investigator
  
  TOKORO(MABUCHI) Miyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hyogo University of Health Sciences
Design and synthesis of novel PCA-1 inhibitor for clinical anticancer drug
- Principal Investigator
  
  TANAKA AKITO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hyogo University of Health Sciences

All 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Novel Metabolically Stable PCA-1/ALKBH3 Inhibitor Has Potent Antiproliferative Effects on DU145 Cells In Vivo.2018
- Author(s)
  Ueda M, Shimizu T, Mabuchi M, Horiike K, Kitae K, Hase H, Ueda Y, Tsujikawa K, Tanaka A
- Journal Title
  
  Anticancer Res.
  
  Volume: 38 Issue: 1 Pages: 211-218
- DOI
  10.21873/anticanres.12210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07186, KAKENHI-PROJECT-15K08036
[Journal Article] Systematic Trial for Evaluating Docetaxel in a Human Prostate Cancer Cell DU145 Xenograft Model2017
- Author(s)
  MIYUKI MABUCHI, MASAHIRO UEDA, YURI YOSHIDA, KOTA HORIIKE, KENTA YAMAOKA, SYUHEI NAKAO, TADASHI SHIMIZU, YUKO UEDA, KAZUTAKE TSUJIKAWA, AKITO TANAKA
- Journal Title
  
  anticancer research
  
  Volume: 37 Issue: 4 Pages: 1665-1676
- DOI
  10.21873/anticanres.11496
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460164, KAKENHI-PROJECT-15K08036, KAKENHI-PROJECT-16K07186
[Journal Article] 3.Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK5062015
- Author(s)
  Mabuchi M, Shimizu T, Ueda M, Mitamura K, Ikegawa S, Tanaka A.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 14 Pages: 2788-2792
- DOI
  10.1016/j.bmcl.2015.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460211, KAKENHI-PROJECT-15K08036
[Presentation] 新規固相担体AquaFirmusの応用研究（１）2016
- Author(s)
  馬渕美雪
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都テルサ　テルサホール（京都府京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-15K08036
[Presentation] 前立腺癌治療薬を目指したprostate cancer antigen-1(PCA-1/ALKBH3)阻害剤HUHS015のデザインと合成2014
- Author(s)
  中尾周平,　清水忠,　馬渕美雪,　上田昌宏,　上田裕子,　辻川和丈,　田中明人
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26460164
[Presentation] 前立腺癌治療薬を目指した創薬研究：新規PCA-1阻害剤HUHS015の塩検討による体内動態改善およびXenograft model薬効向上研究2014
- Author(s)
  馬渕美雪, 清水忠, 笹川由香, 中尾周平, 上田昌宏, 上田裕子,辻川和丈,　田中明人
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26460164

1. TANAKA AKITO (30454789)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. TSUJIKAWA KAZUTAKE (10207376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. INOUE TAKASHI (20263204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山下政克 (00311605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 清水忠 (40509022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 篠山隆司 (10379399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 高良恒史 (00329939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 中尾周平 (90868605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 長野秀嗣 (31003494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 三田村邦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOKORO MIYUKI 所 美雪 (馬渕 美雪)

TOKORO(MABUCHI) MIYUKI 所 美雪

馬渕美雪

MABUCHI MIYUKI 馬渕 美雪

Research Projects

Research Products

Co-Researchers

臨床ビッグデータ情報と医薬品代謝物への構造変化を基軸した膠芽腫治療薬の創製

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovery of anti-allergic drugs regulating a novel target molecule, Rab, identified by affinity technology.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug discovery research for clinical application of PCA-1 inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Design and synthesis of novel PCA-1 inhibitor for clinical anticancer drug

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Novel Metabolically Stable PCA-1/ALKBH3 Inhibitor Has Potent Antiproliferative Effects on DU145 Cells In Vivo.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systematic Trial for Evaluating Docetaxel in a Human Prostate Cancer Cell DU145 Xenograft Model2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 3.Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK5062015

Author(s)

Journal Title

DOI

Data Source

[Presentation] 新規固相担体AquaFirmusの応用研究（１）2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 前立腺癌治療薬を目指したprostate cancer antigen-1(PCA-1/ALKBH3)阻害剤HUHS015のデザインと合成2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 前立腺癌治療薬を目指した創薬研究：新規PCA-1阻害剤HUHS015の塩検討による体内動態改善およびXenograft model薬効向上研究2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

TOKORO MIYUKI 所美雪 (馬渕美雪)

TOKORO(MABUCHI) MIYUKI 所美雪

MABUCHI MIYUKI 馬渕美雪