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yoshioka yusuke  吉岡 祐亮

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Yoshioka Yusuke  吉岡 祐亮

吉岡祐亮

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Researcher Number 60721503
Other IDs
Affiliation (Current) 2025: 東京医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2024: 東京医科大学, 医学部, 講師
2019 – 2024: 東京医科大学, 医学部, 講師(特任)
2015 – 2018: 国立研究開発法人国立がん研究センター, 研究所, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor therapeutics
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56020:Orthopedics-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55040:Respiratory surgery-related / Basic Section 56030:Urology-related / Respiratory organ internal medicine
Keywords
Principal Investigator
細胞外小胞 / Exosome / がんの転移 / がん / エクソソーム / Extracellular vesicles / 転移 / がん転移 / 低分子化合物 / マイクロRNA … More / 腫瘍 / スクリーニング / 治療 / microRNA … More
Except Principal Investigator
エクソソーム / リキッドバイオプシー / 肺癌 / バイオマーカー / 骨転移 / 組織修復 / バイオインフォマティクス解析 / バイオインフォマティックス解析 / miRNA / 変形性関節症 / 間葉系幹細胞 / セクレトーム / mRNA / 急性拒絶反応 / 腎移植 / 小細胞癌 / 膀胱腔内注入療法 / ExoScreen / CD55 / 膀胱癌 / マイクロパーティクル / ARDS / 細胞外小胞 / IPF / COPD Less
  • Research Projects

    (8 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (16 People)
  •  エクソソームおよびマイクロRNA測定による新たな腎移植後慢性拒絶反応の診断法の開発

    • Principal Investigator
      岩本 整
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Tokyo Medical University
  •  Development of novel therapeutic approach using serum exosomes to conquer bone metastases from lung cancer

    • Principal Investigator
      工藤 勇人
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tokyo Medical University
  •  小細胞肺癌における神経変性疾患関連分子の役割の解明と新規個別化治療への応用

    • Principal Investigator
      嶋田 善久
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Tokyo Medical University
  •  変形性関節症に対する間葉系間質細胞由来セクレトーム治療における作用機序の解明

    • Principal Investigator
      中村 憲正
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Osaka University
  •  Novel method for diagnosis and therapy of bladder cancer by targeting urinary CD55/CD9 double-positive exosomes

    • Principal Investigator
      Kikuchi Eiji
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      St. Marianna University School of Medicine
  •  Discovery of an inhibitor for exosome secretion in cancer cells using a small-molecule library approach.Principal Investigator

    • Principal Investigator
      Yoshioka Yusuke
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Tokyo Medical University
  •  Identification of exosome secretion-suppressive miRNAs and its target genes.Principal Investigator

    • Principal Investigator
      Yoshioka Yusuke
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      National Cancer Center Japan
  •  The analyses of cell type-specific extracellular vesicles derived from lung quiescent or cytokine-activated lung endothelial cells

    • Principal Investigator
      YAMADA MITSUHIRO
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Tohoku University

All 2023 2022 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book

  • [Book] 決定版エクソソーム実験ガイド2020

    • Author(s)
      吉岡 祐亮、落谷 孝広
    • Total Pages
      199
    • Publisher
      羊土社
    • ISBN
      9784758122467
    • Data Source
      KAKENHI-PROJECT-19K16848
  • [Book] 医療を変えるエクソソーム2018

    • Author(s)
      落谷 孝広、吉岡 祐亮
    • Total Pages
      240
    • Publisher
      化学同人
    • ISBN
      9784759819786
    • Data Source
      KAKENHI-PROJECT-16K07189
  • [Journal Article] High‐grade bladder cancer cells secrete extracellular vesicles containing miRNA‐146a‐5p and promotes angiogenesis2022

    • Author(s)
      Prieto‐Vila Marta、Usuba Wataru、Yoshioka Yusuke、Takeshita Fumitaka、Yoshiike Miki、Sasaki Hideo、Yamamoto Yusuke、Kikuchi Eiji、Ochiya Takahiro
    • Journal Title

      Journal of Extracellular Biology

      Volume: 1 Issue: 8

    • DOI

      10.1002/jex2.47

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09384, KAKENHI-PROJECT-21K16759, KAKENHI-PROJECT-21H02721, KAKENHI-PROJECT-20K07580
  • [Journal Article] Extracellular Vesicles in Cancer Metastasis: Potential as Therapeutic Targets and Materials2020

    • Author(s)
      Kogure Akiko、Yoshioka Yusuke、Ochiya Takahiro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 12 Pages: 4463-4463

    • DOI

      10.3390/ijms21124463

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16848
  • [Journal Article] Serum extracellular vesicular miR-21-5p is a predictor of the prognosis in idiopathic pulmonary fibrosis.2016

    • Author(s)
      Makiguchi T, Yamada M, Yoshioka Y, Sugiura H, Koarai A, Chiba S, Fujino N, Tojo Y, Ota C, Kubo H, Kobayashi S, Yanai M, Shimura S, Ochiya T, Ichinose M.
    • Journal Title

      Respir Res

      Volume: 17 Issue: 1 Pages: 110-110

    • DOI

      10.1186/s12931-016-0427-3

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05307, KAKENHI-PROJECT-26293195, KAKENHI-PROJECT-15K09206, KAKENHI-PROJECT-16K15453
  • [Presentation] 尿中CD55/CD9共陽性エクソソームは膀胱癌の新規診断バイオマーカーかつ予後進展に関与する2023

    • Author(s)
      薄場渉, 吉池美紀, 荒武里衣, 吉岡祐亮, 山田龍治, 早川望, 落谷孝広, 菊地栄次
    • Organizer
      第110回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-21K09384
  • [Presentation] 膀胱がんにおける尿中エクソソームの表面抗原CD55・CD9と内包物質miR-146a-5pのバイオマーカーとしての検討.2023

    • Author(s)
      薄場渉, 吉池美紀, 荒武里衣, 吉岡祐亮, 山田龍治, 早川望, 落谷孝弘, 菊地栄次.
    • Organizer
      第32回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-21K09384
  • [Presentation] CD55 positive exosomes as a novel urinary biomarker for bladder cancer.2022

    • Author(s)
      Hayakawa Nozomi, Yamada Ryuji, Aratake Satoe, Yoshiike Miki, Usuba Wataru, Yoshioka Yusuke, Ochiya Takahiro, Kikuchi Eiji.
    • Organizer
      19th Urological Association of Asia Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09384
  • [Presentation] Role of Extracellular Vesicles in Cancer: Possible Diagnostic and Therapeutic Applications.2020

    • Author(s)
      Yusuke Yoshioka, Takahiro Ochiya.
    • Organizer
      Japan Association for Animal Cell Technology 2020
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16848
  • [Presentation] 細胞外小胞エクソソームの生理学的機能と臨床応用: エクソソームは生体ネットワーク解析の新たなツールとなりうるか?2020

    • Author(s)
      吉岡祐亮, 落谷孝広
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K16848
  • [Presentation] エクソソーム分泌を阻害する低分子化合物のスクリーニング (Discovery of an inhibitor for EV secretion in cancer cells using a small-molecule library)2019

    • Author(s)
      吉岡祐亮, 横井暁, 落谷孝広.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K16848
  • [Presentation] エクソソーム分泌を阻害する低分子化合物のスクリーニング2019

    • Author(s)
      吉岡祐亮, 横井暁, 落谷孝広.
    • Organizer
      第6回日本細胞外小胞学会
    • Data Source
      KAKENHI-PROJECT-19K16848
  • [Presentation] エクソソームを標的とした新規がん治療法の開発2018

    • Author(s)
      吉岡祐亮, 小坂展慶, 落谷孝広.
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K07189
  • [Presentation] NAPG can regulate tumour-specific EV secretion.2017

    • Author(s)
      Yusuke Yoshioka, Nobuyoshi Kosaka, Takahiro Ochiya.
    • Organizer
      6th International meeting of ISEV
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07189
  • [Presentation] 新規エクソソーム分泌制御因子の同定と治療応用.2017

    • Author(s)
      吉岡祐亮, 小坂 展慶, 落谷 孝広
    • Organizer
      ConBio 2017 (第40回日本分子生物学会)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K07189
  • [Presentation] MicroRNAs as a regulator of extracellular vesicle secretion in cancer cells.2017

    • Author(s)
      Yusuke Yoshioka, Nobuyoshi Kosaka, Takahiro Ochiya
    • Organizer
      第76回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K07189
  • [Presentation] NAPG による細胞外小胞の分泌抑制とがん治療効果の検証.2017

    • Author(s)
      吉岡祐亮, 小坂展慶, 落谷孝広.
    • Organizer
      第4回細胞外小胞学会
    • Data Source
      KAKENHI-PROJECT-16K07189
  • [Presentation] Identification of serum extracellular vesicle microRNA as a biomarker for prognosis in idiopathic pulmonary fibrosis2016

    • Author(s)
      Tomonori Makiguchi , Mitsuhiro Yamada , Yusuke Yoshioka , Hisatoshi Sugiura , Akira Koarai , Hiroshi Kubo , Takahiro Ochiya , Masakazu Ichinose
    • Organizer
      ATS 2016
    • Place of Presentation
      サンフランシスコ、米国
    • Year and Date
      2016-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09206
  • [Presentation] 特発性肺線維症の予後予測因子としての血清エクソソームmicroRNA2016

    • Author(s)
      牧口友紀、山田充啓、吉岡祐亮、杉浦久敏、小荒井晃、大田千晴、久保裕司、小林誠一、矢内勝、志村早苗、落谷孝広、一ノ瀬正和
    • Organizer
      第56回 日本呼吸器学会学術講演会
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2016-04-10
    • Data Source
      KAKENHI-PROJECT-15K09206
  • [Presentation] エクソソーム分泌を制御するマイクロRNAと標的遺伝子の同定2016

    • Author(s)
      吉岡祐亮、小坂展慶、富永直臣、山本雄介、落谷孝広
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K07189
  • [Presentation] 細胞外小胞エクソソームの分泌を阻害するmicroRNAおよびその標的遺伝子の同定2016

    • Author(s)
      吉岡祐亮、小坂展慶、富永直臣、山本雄介、落谷孝広
    • Organizer
      第3回日本細胞外小胞学会
    • Place of Presentation
      グランドプリンスホテル広島(広島県広島市)
    • Year and Date
      2016-08-31
    • Data Source
      KAKENHI-PROJECT-16K07189
  • [Presentation] 炎症刺激・酸化・ニトロ化ストレス下の血管内皮細胞由来エクソソームの動態2015

    • Author(s)
      牧口友紀,山田充啓,吉岡祐亮,杉浦久敏,小荒井晃,久保裕司,落谷孝広,一ノ瀬正和
    • Organizer
      第55回日本呼吸器学会学術講演会
    • Place of Presentation
      東京、東京国際フォーラム
    • Year and Date
      2015-04-18
    • Data Source
      KAKENHI-PROJECT-15K09206
  • [Presentation] The Detection of Cell Type-Specific Extracellular Vesicles Derived from Lung Epithelial Cells, Stable or Cytokine-Activated Endothelial Cells by Exoscreen.2015

    • Author(s)
      Makiguchi T, Yamada M, Yoshioka Y, Sugiura H, Koarai A, Kubo H, Ochiya T, Kikuchi T, Ichinose M.
    • Organizer
      American Thoracic Society International Conference
    • Place of Presentation
      Denver, USA
    • Year and Date
      2015-05-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09206
  • 1.  落谷 孝広 (60192530)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  YAMADA MITSUHIRO (00396483)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 3.  Kikuchi Eiji (10286552)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  薄場 渉 (90867649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 5.  嶋田 善久 (00459497)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  池田 徳彦 (70246205)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  岩本 整 (00338831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  上野 琢哉 (00296469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  今野 理 (50385027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  尾田 高志 (90531187)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  中村 憲正 (50273719)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  辻井 聡 (70898014)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  工藤 勇人 (80623800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  竹下 文隆 (40466199)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Sugiura Hisatosi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  一ノ瀬 正和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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