Tanaka Hiroki 田中浩揮

Researcher Number	60801743
Other IDs
Affiliation (Current)	2025: 東北大学, 薬学研究科, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 東北大学, 薬学研究科, 准教授 2023: 東北大学, 薬学研究科, 助教 2020 – 2022: 千葉大学, 大学院薬学研究院, 助教 2017 – 2019: 千葉大学, 大学院薬学研究院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 90120:Biomaterials-related / Basic Section 90110:Biomedical engineering-related / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Basic Section 90120:Biomaterials-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator ドラッグデリバリーシステム / 炎症性疾患 / Lipid nanoparticles / mRNAデリバリー / mRNA送達 / ドラッグデリバリー / ナノ粒子 / 遺伝子治療 / mRNA / RNAデリバリー … More / 免疫抑制 / Lipid nanodparticles / 自己免疫疾患 / 細胞内動態 / 炎症 / Drug Delivery System / リポソーム / 炎症性腸疾患 / 遺伝子 / 核酸 / 遺伝子導入 / 自己分解性材料 … More Except Principal Investigator Nose-to-Brain / ゲノム編集 / RNA送達 / 神経変性疾患 / 脳内伝播 / 共集合化ナノ粒子 / mRNAデリバリー / がん抗原 / RNA / ワクチン / 脂質ナノ粒子 / ネオ抗原 / 癌治療 / 凍結乾燥 / ＲＮＡワクチン / 癌免疫 / RNAワクチン / DDS / 機能性ペプチド / 脂質様材料 / siRNAデリバリー / 海馬 / 脂質材料 / 膜透過性ペプチド / ミクログリア / マイクロ流体デバイス / 核酸デリバリー / 多成分集合型ナノ粒子 / グリア標的治療 / ナノ粒子 / 核酸DDS Less

Development of "Immune Stealth LNP" for mRNA-based gene therapyPrincipal Investigator
- Principal Investigator
  
  田中浩揮
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Tohoku University
脳内病態伝播拠点標的RNA送達Nose-to-Brainミセル開発と脳神経ゲノム編集治療基盤構築
- Principal Investigator
  
  金沢貴憲
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokushima
  University of Shizuoka
Ready-tp-Use RNA-drug discovery for the acceleration of personalized cancer vaccine
- Principal Investigator
  
  秋田英万
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Tohoku University
  Chiba University
Development of immunosuppressive dendritic cells and autoimmune disease treatment based on mRNA delivery technologyPrincipal Investigator
- Principal Investigator
  
  Tanaka Hiroki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Tohoku University
  Chiba University
Development of nucleic acid delivery nano-DDS based on nose-to-brain route and its application to glia targeted therapy
- Principal Investigator
  
  Takanori Kanazawa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  University of Shizuoka
Development of self-degradable lipid like material based on intraparticle reactionPrincipal Investigator
- Principal Investigator
  
  Tanaka Hiroki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Chiba University
pH感受性脂質の分子改変による炎症組織の細胞内ポリソームを標的としたmRNA送達Principal Investigator
- Principal Investigator
  
  田中浩揮
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Chiba University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book Patent

[Book] mRNAを製造するための原料：細胞内環境応答性脂質ナノ粒子によるDDS効果の向上（14章）2023
- Author(s)
  田中浩揮、秋田英万
- Total Pages
  10
- Publisher
  技術情報協会
- ISBN
  9784861049378
- Data Source
  KAKENHI-PROJECT-21K18035
[Book] 医薬品におけるDDS技術開発と製剤への応用（4章2節）2021
- Author(s)
  田中浩揮、秋田英万
- Total Pages
  401
- Publisher
  情報機構
- ISBN
  9784865022278
- Data Source
  KAKENHI-PROJECT-21K18035
[Book] 創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術（6章7節）2021
- Author(s)
  田中浩揮、秋田英万
- Total Pages
  598
- Publisher
  技術情報協会
- ISBN
  9784861048562
- Data Source
  KAKENHI-PROJECT-21K18035
[Journal Article] The Effect of Cholesterol Content on the Adjuvant Activity of Nucleic-Acid-Free Lipid Nanoparticles2024
- Author(s)
  Anindita Jessica、Tanaka Hiroki、Yamakawa Takuma、Sato Yuka、Matsumoto Chika、Ishizaki Kota、Oyama Taiji、Suzuki Satoko、Ueda Keisuke、Higashi Kenjirou、Moribe Kunikazu、Sasaki Kasumi、Ogura Yumika、Yonemochi Etsuo、Sakurai Yu、Hatakeyama Hiroto、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 16 Issue: 2 Pages: 181-181
- DOI
  10.3390/pharmaceutics16020181
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-21K18035
[Journal Article] Lymphatic Endothelial Cells Produce Chemokines in Response to the Lipid Nanoparticles Used in RNA Vaccines2024
- Author(s)
  Liu Yi、Suzuoki Miho、Tanaka Hiroki、Sakurai Yu、Hatakeyama Hiroto、Akita Hidetaka
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 47 Issue: 3 Pages: 698-707
- DOI
  10.1248/bpb.b23-00689
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2024-03-26
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18035
[Journal Article] An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses2023
- Author(s)
  Oyama Ryotaro、Ishigame Harumichi、Tanaka Hiroki、Tateshita Naho、Itazawa Moeko、Imai Ryosuke、Nishiumi Naomasa、Kishikawa Jun-ichi、Kato Takayuki、Anindita Jessica、Nishikawa Yoshifumi、Maeki Masatoshi、Tokeshi Manabu、Tange Kota、Nakai Yuta、Sakurai Yu、Okada Takaharu、Akita Hidetaka
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 19 Pages: 18758-18774
- DOI
  10.1021/acsnano.3c02251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-20KK0152, KAKENHI-PROJECT-21K18035
[Journal Article] Reactivation of Anticancer Immunity by Resetting Interorgan Crosstalk in Immune-Suppressive Cells with a Nanoparticulated Anti-Inflammatory Drug2023
- Author(s)
  Doi M, Tanaka H, Ohoto T, Miura N, Sakurai Y, Hatakeyama H, Akita H
- Journal Title
  
  Small
  
  Volume: - Issue: 16
- DOI
  10.1002/smll.202205131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-21K18035
[Journal Article] Ready-to-Use-Type Lyophilized Lipid Nanoparticle Formulation for the Postencapsulation of Messenger RNA2023
- Author(s)
  Tanaka Hiroki、Hagiwara Shinya、Shirane Daiki、Yamakawa Takuma、Sato Yuka、Matsumoto Chika、Ishizaki Kota、Hishinuma Miho、Chida Katsuyuki、Sasaki Kasumi、Yonemochi Etsuo、Ueda Keisuke、Higashi Kenjirou、Moribe Kunikazu、Tadokoro Takashi、Maenaka Katsumi、Taneichi Sakura、et al.
- Journal Title
  
  ACS Nano
  
  Volume: 17 Issue: 3 Pages: 2588-2601
- DOI
  10.1021/acsnano.2c10501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06545, KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-21K18035
[Journal Article] siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles2023
- Author(s)
  Sakurai Y, Yoshikawa K, Arai K, Kazaoka A, Aoki S, Ito K, Nakai Y, Tange K, Furihata T, Tanaka H, Akita H
- Journal Title
  
  J Control Release
  
  Volume: 353 Pages: 122-135
- DOI
  10.1016/j.jconrel.2022.11.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18320
[Journal Article] Development of an Alcohol Dilution?Lyophilization Method for the Preparation of mRNA-LNPs with Improved Storage Stability2023
- Author(s)
  Shirane Daiki、Tanaka Hiroki、Sakurai Yu、Taneichi Sakura、Nakai Yuta、Tange Kota、Ishii Itsuko、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 15 Issue: 7 Pages: 1819-1819
- DOI
  10.3390/pharmaceutics15071819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18035
[Journal Article] Development of a Ready-to-Use-Type RNA Vaccine Carrier Based on an Intracellular Environment-Responsive Lipid-like Material with Immune-Activating Vitamin E Scaffolds2023
- Author(s)
  Anindita Jessica、Tanaka Hiroki、Oyama Ryotaro、Hagiwara Shinya、Shirane Daiki、Taneichi Sakura、Nakai Yuta、Tange Kota、Hatakeyama Hiroto、Sakurai Yu、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 15 Issue: 12 Pages: 2702-2702
- DOI
  10.3390/pharmaceutics15122702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-21K18035
[Journal Article] 細胞内動態・崩壊性を制御するDDS材料としての脂質様材料の分子デザイン2022
- Author(s)
  田中浩揮、秋田英万
- Journal Title
  
  有機合成化学協会誌
  
  Volume: 80 Pages: 55-63
- NAID
  130008141123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K18035
[Journal Article] Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine‐Loaded Lipid Nanoparticles2022
- Author(s)
  Masaki Gomi, Yu Sakurai, Minami Sato, Hiroki Tanaka, Yumi Miyatake, Koichi Fujiwara, Mizuki Watanabe, Satoshi Shuto, Yuta Nakai, Kota Tange, Hiroto Hatakeyama, Hidetaka Akita
- Journal Title
  
  Advanced Healthcare Materials
  
  Volume: 12 Issue: 9 Pages: 2202528-2202528
- DOI
  10.1002/adhm.202202528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06494, KAKENHI-PROJECT-21K18320, KAKENHI-PROJECT-19K06965, KAKENHI-PROJECT-22KJ0465
[Journal Article] Investigation of the Transport Pathways Associated with Enhanced Brain Delivery of Peptide Drugs by Intranasal Coadministration with Penetratin2021
- Author(s)
  Kamei Noriyasu、Suwabe Susumu、Arime Kenji、Bando Hidemi、Murata Kaho、Yamaguchi Maika、Yokoyama Natsuki、Tanaka Erina、Hashimoto Ayaka、Kanazawa Takanori、Ago Yukio、Takeda-Morishita Mariko
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 11 Pages: 1745-1745
- DOI
  10.3390/pharmaceutics13111745
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07032, KAKENHI-PROJECT-20H04537
[Journal Article] Proteomics Analysis of Lymphatic Metastasis-Related Proteins Using Highly Metastatic Human Melanoma Cells Originated by Sequential in Vivo Implantation2021
- Author(s)
 Chida Katsuyuki、Sakurai Yu、Ohtani Asa、Masuda Takeshi、Ohtsuki Sumio、Tanaka Hiroki、Akita Hidetaka
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 44 Issue: 10 Pages: 1551-1556
- DOI
 10.1248/bpb.b21-00463
- NAID
 130008095758
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2021-10-01
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19K05544, KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-21K18035
[Journal Article] Improvement of mRNA Delivery Efficiency to a T Cell Line by Modulating PEG-Lipid Content and Phospholipid Components of Lipid Nanoparticles2021
- Author(s)
  Tanaka Hiroki、Miyama Ryo、Sakurai Yu、Tamagawa Shinya、Nakai Yuta、Tange Kota、Yoshioka Hiroki、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 12 Pages: 2097-2097
- DOI
  10.3390/pharmaceutics13122097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-20H00657, KAKENHI-PROJECT-21K18035
[Journal Article] Optimization of Sentinel Lymph Node Imaging Methodology Using Anionic Liposome and Hyaluronidase2021
- Author(s)
  Sakurai Yu、Suzuoki Miho、Gomi Masaki、Tanaka Hiroki、Akita Hidetaka
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 9 Pages: 1462-1462
- DOI
  10.3390/pharmaceutics13091462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-21K18035, KAKENHI-PROJECT-22KJ0465
[Journal Article] Self‐Degradable Lipid‐Like Materials Based on “Hydrolysis accelerated by the intra‐Particle Enrichment of Reactant (HyPER)” for Messenger RNA Delivery2020
- Author(s)
  Tanaka Hiroki、...Sakurai Yu、Ueda Keisuke、Higashi Kenjirou、Moribe Kunikazu、Shinsho Eiji、Nishida Ruka、Fukuzawa Kaori、Yonemochi Etsuo、Okuwaki Koji、Mochizuki Yuji、Nakai Yuta、Tange Kota、Yoshioka Hiroki、Tamagawa Shinya、Akita Hidetaka
- Journal Title
  
  Advanced Functional Materials
  
  Volume: 30 Issue: 34 Pages: 1910575-1910575
- DOI
  10.1002/adfm.201910575
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20195, KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-20H00657
[Journal Article] Vitamin E Scaffolds of pH-Responsive Lipid Nanoparticles as DNA Vaccines in Cancer and Protozoan Infection.2020
- Author(s)
  Maeta M, Miura N, Tanaka H, Nakamura T, Kawanishi R, Nishikawa Y, Asano K, Tanaka M, Tamagawa S, Nakai Y, Tange K, Yoshioka H, Harashima H, Akita H.
- Journal Title
  
  Mol Pharm.
  
  Volume: 17 Issue: 4 Pages: 1237-1247
- DOI
  10.1021/acs.molpharmaceut.9b01262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21359, KAKENHI-PROJECT-20KK0152, KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-20H00657, KAKENHI-PROJECT-20H03473
[Journal Article] Development of lipid-like materials for RNA delivery based on intracellular environment-responsive membrane destabilization and spontaneous collapse.2020
- Author(s)
  Tanaka H, Sakurai Y, Anindita J, Akita H.
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: 154-155 Pages: 210-226
- DOI
  10.1016/j.addr.2020.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18377
[Journal Article] Development of a lipoplex-type mRNA carrier composed of an ionizable lipid with a vitamin E scaffold and the KALA peptide for use as an ex vivo dendritic cell-based cancer vaccine2019
- Author(s)
  Tateshita N, Miura N, Tanaka H, Masuda T, Ohtsuki S, Tange K, Nakai Y, Yoshioka H, Akita H
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 310 Pages: 36-46
- DOI
  10.1016/j.jconrel.2019.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-19K05544
[Journal Article] Inhibition of the Inflammatory Pathway Enhances Both the in Vitro and in Vivo Transfection Activity of Exogenous in Vitro-Transcribed mRNAs Delivered by Lipid Nanoparticles2019
- Author(s)
 Ohto T, Konishi M, Tanaka H, Onomoto K, Yoneyama M, Nakai Y, Tange K, Yoshioka H, Akita H
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 42 Issue: 2 Pages: 299-302
- DOI
 10.1248/bpb.b18-00783
- NAID
 130007587594
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2019-02-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-17K15699
[Journal Article] Development of an Alcohol Dilution–Lyophilization Method for Preparing Lipid Nanoparticles Containing Encapsulated siRNA2018
- Author(s)
  Shirane D, Tanaka H, Nakai Y, Yoshioka H, Akita H
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 8 Pages: 1291-1294
- DOI
  10.1248/bpb.b18-00208
- NAID
  130007429032
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2018-08-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18377
[Journal Article] In vivo Introduction of mRNA Encapsulated in Lipid-Nano-Particles to Brain Neuronal Cells and Astrocytes via Intracerebroventricular Administration.2018
- Author(s)
  Hiroki Tanaka, Taichi Nakatani, Tomomi Furihara, Kota Tange, Yuta Nakai, Hiroki Yoshioka, Hideyoshi Harashima, Hidetaka Akita.
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06558
[Journal Article] The delivery of mRNA to colon inflammatory lesions by lipid-nano-particles containing environmentally-sensitive lipid-like materials with oleic acid scaffolds.2018
- Author(s)
  Tanaka H, Watanabe A, Konishi M, Nakai Y, Yoshioka H, Ohkawara T, Takeda H, Harashima H, Akita H.
- Journal Title
  
  Heliyon
  
  Volume: 4 Issue: 12 Pages: e00959-e00959
- DOI
  10.1016/j.heliyon.2018.e00959
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05500, KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-17K19473
[Journal Article] In Vivo Introduction of mRNA Encapsulated in Lipid Nanoparticles to Brain Neuronal Cells and Astrocytes via Intracerebroventricular Administration.2018
- Author(s)
  Tanaka H, Nakatani T, Frihata T, Tange K, Nakai Y, Yoshioka H, Harashima H, Akita H.
- Journal Title
  
  Mol Pharm
  
  Volume: 15 Issue: 5 Pages: 2060-2067
- DOI
  10.1021/acs.molpharmaceut.7b01084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-17K19473
[Journal Article] A hepatic pDNA delivery system based on an intracellular environment sensitive vitamin E-scaffold lipid-like material with the aid of an anti-inflammatory drug.2018
- Author(s)
  Togashi R, Tanaka H, Nakamura S, Yokota H, Tange K, Nakai Y, Yoshioka H, Harashima H, Akita H
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 279 Pages: 262-270
- DOI
  10.1016/j.jconrel.2018.04.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18377, KAKENHI-PROJECT-17K19473
[Journal Article] DNA-loaded nano-adjuvant formed with a vitamin E-scaffold intracellular environmentally-responsive lipid-like material for cancer immunotherapy.2018
- Author(s)
  Kawai M, Nakamura T, Mura N, Maeta M, Tanaka H, Ueda K, Higashi K, Moribe K, Tange K, Nakai Y, Yoshioka H, Harashima H, Akita H
- Journal Title
  
  Nanomedicine
  
  Volume: 14 Issue: 8 Pages: 2587-2597
- DOI
  10.1016/j.nano.2018.08.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K18377
[Journal Article] 環境応答性脂質様材料：ssPalmを基盤とした体内・細胞内動態制御技術　～遺伝子・核酸デリバリーへの応用を中心として～2017
- Author(s)
  田中浩揮・秋田英万
- Journal Title
  
  細胞(Cell)10月臨時増刊号　特集：ナノマテリアルとDDS
  
  Volume: 49 Pages: 597-601
- Data Source
  KAKENHI-PROJECT-17H06558
[Journal Article] 環境応答性脂質様材料：ssPalmを基盤としたナノテクノロジー　～遺伝子・核酸デリバリーへの応用展開～2017
- Author(s)
  田中浩揮、三浦尚也、秋田英万
- Journal Title
  
  医学のあゆみ
  
  Volume: 262 Pages: 131-136
- Data Source
  KAKENHI-PROJECT-17H06558
[Patent] 脂質ナノ粒子の凍結乾燥組成物2020
- Inventor(s)
  秋田英万、田中浩揮ほか
- Industrial Property Rights Holder
  秋田英万、田中浩揮ほか
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-18K18377
[Patent] 細胞内動態を改善した新規カチオン性脂質2019
- Inventor(s)
  秋田英万、田中浩揮他
- Industrial Property Rights Holder
  秋田英万、田中浩揮他
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K18377
[Patent] 細胞内動態を改善した新規カチオン性脂質2018
- Inventor(s)
  秋田英万、田中浩揮、吉岡宏樹、丹下耕太、中井悠太、他４名
- Industrial Property Rights Holder
  秋田英万、田中浩揮、吉岡宏樹、丹下耕太、中井悠太、他４名
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H06558
[Presentation] Contribution of lipid composition and morphology of lipid nanoparticle to its immunostimulatory properties2024
- Author(s)
  essica Anindita, 田中浩揮、山川拓真、佐藤裕果、石崎弘汰、松本千佳、植田圭祐、東顕二郎、森部久仁一、佐々木香純、米持悦生、櫻井遊、秋田英万
- Organizer
  日本薬剤学会　第38年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] ビタミンE足場型pH応答性脂質様材料を用いたRNAワクチンによる細胞性免疫の活性化2024
- Author(s)
  大山遼太朗、石亀晴道、田中浩揮、西川義文、岡田峰陽、秋田英万
- Organizer
  第22回遺伝子・デリバリー研究会シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] Lipid composition and morphology of lipid nanoparticle contributed to its immuostimulatory properties2024
- Author(s)
  Jessica Anindita, 田中浩揮、植田圭祐、東顕二郎、森部久仁一、佐々木香純、米持悦生、櫻井遊、秋田英万
- Organizer
  日本DDS学会　第39年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 2本鎖アンチセンスオリゴ核酸内封 Ready-to-Use型脂質ナノ粒子の開発2024
- Author(s)
  松本千佳、田中浩揮、佐藤裕果、中井悠太、丹下耕太、櫻井遊、秋田英万
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] In vitro系を用いた脂質ナノ粒子（LNP）の免疫刺激性の解析2023
- Author(s)
  劉怡、鈴置真歩、田中浩揮、櫻井遊、秋田英万
- Organizer
  日本薬剤学会　第38年会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ビタミンE足場型pH応答性脂質様材料を用いたRNAワクチンによる細胞性免疫の活性化2023
- Author(s)
  大山遼太朗、石亀晴道、田中浩揮、西川義文、岡田峰陽、秋田英万
- Organizer
  第22回遺伝子・デリバリー研究会シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 「使用者の利便性を追求したmRNA-LNP製剤の開発」2022
- Author(s)
  田中浩揮、秋田英万
- Organizer
  日本薬剤学会第37年会学術シンポジウム4
- Invited
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ビタミンE足場型材料が誘導する免疫活性化メカニズムの解明2022
- Author(s)
  大山遼太朗、Jessica Anindita、田中浩揮、櫻井遊、石亀晴道、岡田峰陽、丹下耕太、中井悠太、吉岡宏樹、秋田英万
- Organizer
  遺伝子・デリバリー研究会第21回シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] リンパ球指向性を有する脂質ナノ粒子の開発2022
- Author(s)
  岩崎光希、櫻井遊、丹下耕太、中井悠太、田中浩揮、秋田英万
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 脳を標的とするNose-to-Brain型mRNA送達技術の開発2022
- Author(s)
  藤田翔也，田中浩揮，櫻井遊，中井悠太，丹下耕太，金沢貴憲，秋田英万
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 脳を標的とするNose-to-Brain型mRNA送達技術の開発2022
- Author(s)
  藤田翔也、田中浩揮、櫻井遊、中井悠太、丹下耕太、金沢貴憲、秋田英万
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H04537
[Presentation] アニオン性脂質ナノ粒子による脾臓標的化mRNA送達技術の開発2022
- Author(s)
  堀瑞歩、櫻井遊、五味昌樹、中井悠太、丹下耕太、田中浩揮、秋田英万
- Organizer
  第7回日本核酸医薬学会年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] mRNA内封脂質ナノ粒子Ready-to-Use製剤の物性評価2022
- Author(s)
  山川拓真、田中浩揮、萩原伸哉、白根大貴、高田奈依、櫻井遊、福田翔、福澤薫、米持悦生、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  第7回日本核酸医薬学会年会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 抗炎症薬搭載ナノ粒子による組織間の免疫抑制クロストークを標的とした新規がん治療戦略の提唱2022
- Author(s)
  土井瑞貴、大東昴良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 脳を標的とするNose-to-Brain型mRNA送達技術の開発2022
- Author(s)
  山本理奈、藤田翔也、田中浩揮、櫻井遊、中井悠太、丹下耕太、金沢貴憲、秋田英万
- Organizer
  遺伝子・デリバリー研究会第21回シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] Ready-to-Use型mRNA内封脂質ナノ粒子製剤の物性評価2022
- Author(s)
  山川拓真、田中浩揮、萩原伸哉、櫻井遊、佐々木香純、米持悦生、福沢薫、中井悠太、丹下耕太、秋田英万
- Organizer
  遺伝子・デリバリー研究会第21回シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] Ready-to-Use型LNP製剤の開発2022
- Author(s)
  田中浩揮、萩原伸哉、山川拓真、白根大貴、高田奈依、櫻井遊、福田翔、福澤薫、米持悦生、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  第7回日本核酸医薬学会年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 一工程で使用可能なmRNA内封脂質ナノ粒子Ready-to-Use液体製剤の開発2022
- Author(s)
  佐藤裕果、田中浩揮、萩原伸哉、山川拓真、櫻井遊、中井悠太、丹下耕太、秋田英万
- Organizer
  第43回生体膜と薬物相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 脳を標的とするNose-to-Brain型mRNA送達技術の開発2022
- Author(s)
  山本理奈、藤田翔也、田中浩揮、櫻井遊、中井悠太、丹下耕太、金沢貴憲、秋田英万
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] Ready-to-Use型mRNA内封脂質ナノ粒子製剤の物性評価2022
- Author(s)
  山川拓真、田中浩揮、萩原伸哉、櫻井遊、佐々木香純、米持悦生、福澤薫、中井悠太、丹下耕太、秋田英万
- Organizer
  遺伝子・デリバリー研究会　第21回シンポジウム・第20回夏季セミナー
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 一工程で使用可能なmRNA内封脂質ナノ粒子Ready-to-Use液体製剤の開発2022
- Author(s)
  佐藤裕果、田中浩揮、萩原伸哉、山川拓真、櫻井遊、中井悠太、丹下耕太、秋田英万
- Organizer
  第43回生体膜と薬物相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] mRNA delivery to Secondary Lymphoid Tissues by Lipid Nanoparticles Loading Phosphatidylserine2022
- Author(s)
  Gomi M, Sakurai Y, Tanaka H, Sato M, Miyatake Y, Fujiwara K, Watanabe M, Shuto S, Nakai Y, Tange K, Akita H
- Organizer
  NIMS WEEK2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] Ready-to-Use’ ssPalmE-Phe lipid nanoparticle as a platform for RNA-based cancer vaccine delivery2021
- Author(s)
  Jessica Anindita、田中浩揮、大山遼太郎、萩原伸哉、白根大貴、玉川晋也、中井悠太、丹下耕太、吉岡宏樹、秋田英万
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] Ready-to-Use’-type ssPalmE-Phe lipid nanoparticle as a platform for RNA-based vaccine2021
- Author(s)
  Jessica Anindita、田中浩揮、大山遼太郎、萩原伸哉、白根大貴、玉川晋也、中井悠太、丹下耕太、吉岡宏樹、秋田英万
- Organizer
  日本核酸医薬学会第６回年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] ビタミンE足場型新規材料を用いたmRNAがんワクチンの開発とその機能解析2021
- Author(s)
  大山遼太朗，舘下菜穂，Jessica Anindita，田中浩揮，三浦尚也，櫻井遊，石亀晴道，岡田隆陽，丹下耕太，中井裕太，吉岡宏樹，秋田英万
- Organizer
  日本薬剤学会（学生主催シンポジウム）
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 抗腫瘍免疫の正常化を介したRISET療法の作用機序解析と応用展開2021
- Author(s)
  土井瑞貴,　大東昂良, 田中浩揮, 三浦尚也, 櫻井遊秋田英万.
- Organizer
  日本DDS学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 使用者の利便性を限りなく追求したmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 一工程でmRNAを内封できるReady-to-Use型脂質ナノ粒子製剤の創生2021
- Author(s)
  萩原伸哉，田中浩揮，白根大貴，山川拓真，櫻井遊，玉川晋也，中井悠太，丹下耕太，秋田英万
- Organizer
  日本薬学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 脂質ナノ粒子による統合的ストレス応答(ISR)メカニズムの解明2021
- Author(s)
  菱沼美保、田中浩揮、秋田英万
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 自己分解性脂質を用いたsiRNA/ASOの送達2021
- Author(s)
  田中浩揮，高田奈依, 吉田徳幸，井上貴雄，丹下耕太，中井裕太，吉岡宏樹，秋田英万
- Organizer
  核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 使用者の利便性を限りなく追求したmRNA内封脂質ナノ粒子Ready-to-Use製剤の創成2021
- Author(s)
  萩原伸哉，田中浩揮，白根大貴，高田奈依，櫻井遊，玉川晋也，中井悠太，丹下耕太，秋田英万
- Organizer
  日本薬剤学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ワンステップで使用可能なmRNA内封脂質ナノ粒子Ready-to-Use製剤の創成2021
- Author(s)
  萩原伸哉，田中浩揮，白根大貴，高田奈依，櫻井遊，玉川晋也，中井悠太，丹下耕太，秋田英万
- Organizer
  日本DDS学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ビタミンE足場型新規材料を基盤とするmRNAがんワクチンの開発とその機能解析2021
- Author(s)
  大山遼太朗，舘下菜穂，Jessica Anindita，田中浩揮，三浦尚也，櫻井遊，石亀晴道，岡田隆陽，丹下耕太，中井悠太，吉岡宏樹，秋田英万
- Organizer
  日本薬剤学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] pH応答性脂質を基盤としたT細胞へのmRNA送達技術の開発2021
- Author(s)
  三山亮，田中浩揮，中井悠太，櫻井遊，玉川晋也，丹下耕太，秋田英万
- Organizer
  日本DDS学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] mRNA創薬の加速を目指した脂質分子の構造改変と製剤検討2021
- Author(s)
  田中浩揮，秋田英万
- Organizer
  日本薬剤学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 自己分解性脂質を用いたオリゴ核酸の送達2021
- Author(s)
  田中浩揮，高田奈依, 吉田徳幸，井上貴雄，丹下耕太，中井裕太，吉岡宏樹，秋田英万
- Organizer
  日本DDS学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ビタミンE足場型新規材料を基盤とするmRNAワクチンの開発2021
- Author(s)
  山遼太朗，舘下菜穂，Jessica Anindita，田中浩揮，三浦尚也，櫻井遊，石亀晴道，岡田隆陽，丹下耕太，中井裕太，吉岡宏樹，秋田英万
- Organizer
  核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ‘Ready-to-Use’ ssPalmE-Phe lipid nanoparticle as a platform for RNA-based cancer vaccine delivery2021
- Author(s)
  Jessica Anindita, Hiroki Tanaka, Ryotaro Oyama, Shinya Hagiwara, Daiki Shirane1, Shinya Tamagawa, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Hidetaka Akita
- Organizer
  日本薬剤学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 使用者の利便性を限りなく追求したmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] 組織間のクロストークを標的とした新規がん治療戦略の提唱2021
- Author(s)
  土井　瑞貴、大東　昂良、田中　浩揮、三浦　尚也、櫻井　遊、秋田　英万
- Organizer
  日本薬学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] T細胞エンジニアリングを可能とする脂質ナノキャリアの開発2021
- Author(s)
  三山亮，田中浩揮，中井悠太，櫻井遊，玉川晋也，丹下耕太，秋田英万
- Organizer
  日本薬学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 水和の一工程のみで使用可能なmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉，田中浩揮，白根大貴，山川拓真，櫻井遊，玉川晋也，中井悠太，丹下耕太，秋田英万
- Organizer
  核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] 水和の一工程のみで使用可能なmRNA内封脂質ナノ粒子Ready-to-Use製剤の創生2021
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、山川拓真、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  日本核酸医薬学会第６回年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] Ready-to-Use型脂質ナノ粒子製剤の物性評価2021
- Author(s)
  山川拓真，田中浩揮，萩原伸哉，白根大貴，高田奈依，櫻井遊，福田翔，福澤薫，米持悦生，玉川晋也，中井悠太，丹下耕太，秋田英万
- Organizer
  日本薬学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ‘Ready-to-use’ ssPalmE-Phe lipid nanoparticle as a carrier for RNA-based vaccine delivery2021
- Author(s)
  Anindita Jessica、田中浩揮、大山遼太郎、萩原伸哉、白根大貴、玉川晋也、中井悠太、丹下耕太、吉岡宏樹、秋田英万
- Organizer
  日本薬学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] Ready-to-Use' ssPalmE-Phe lipid nanoparticle as a platform for RNA-based cancer vaccine delivery2021
- Author(s)
  31.Jessica Anindita、田中浩揮、大山遼太郎、萩原伸哉、白根大貴、玉川晋也、中井悠太、丹下耕太、吉岡宏樹、秋田英万
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21K18320
[Presentation] ‘Ready-to-Use’-type ssPalmE-Phe lipid nanoparticle as a platform for RNA-based vaccine2021
- Author(s)
  Jessica Anindita, Hiroki Tanaka, Ryotaro Oyama, Shinya Hagiwara, Daiki Shirane1, Shinya Tamagawa, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Hidetaka Akita
- Organizer
  核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ‘Ready-to-Use’ ssPalmE-Phe lipid nanoparticle as a platform for RNA-based cancer vaccine delivery2021
- Author(s)
  Jessica Anindita, Hiroki Tanaka, Ryotaro Oyama, Shinya Hagiwara, Daiki Shirane, Shinya Tamagawa, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Hidetaka Akita
- Organizer
  日本DDS学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] mRNA内封脂質ナノ粒子Ready-to-Use製剤の物性評価2021
- Author(s)
  山川拓真，萩原伸哉，田中浩揮，白根大貴，高田奈依，櫻井遊，福田翔，福澤薫，米持悦生，玉川晋也，中井悠太，丹下耕太，秋田英万
- Organizer
  日本DDS学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ビタミンE足場型pH応答性材料が誘導するワクチン効果メカニズムの解明2021
- Author(s)
  大山遼太朗，舘下菜穂，Jessica Anindita，田中浩揮，三浦尚也，櫻井遊，石亀晴道2，岡田隆陽2，丹下耕太3，中井裕太3，吉岡宏樹3，秋田英万1
- Organizer
  日本DDS学会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] ビタミンE足場型材料が誘導する免疫活性化メカニズムの解明2021
- Author(s)
  大山遼太朗, Jessica Anindita, 田中浩揮, 櫻井遊，石亀晴道，岡田峰陽，丹下耕太，中井裕太，吉岡宏樹，秋田英万
- Organizer
  日本薬学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K18035
[Presentation] エマルション型ナノ粒子製剤における薬物の疎水性が血中動態に及ぼす影響2020
- Author(s)
  土井瑞貴、田中浩揮、櫻井遊、秋田英万
- Organizer
  第36回日本DDS学会学術集会　神戸学院大学ポートアイランドキャンパス
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] mRNAとビタミンE足場型の新規pH応答性材料を基盤とするがんワクチン技術の開発2020
- Author(s)
  大山遼太朗、舘下菜穂、Jessica Anindita、田中浩揮、三浦尚也、櫻井遊、石亀晴道、岡田峰陽、秋田英万
- Organizer
  第36回日本DDS学会学術集会神戸学院大学ポートアイランドキャンパス
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] ビタミンE足場型pH応答性新規材料を基盤とするmRNAがんワクチンの開発2020
- Author(s)
  大山遼太朗、舘下菜穂、Jessica Anindita、田中浩揮、三浦尚也、櫻井遊、石亀晴道、岡田峰陽、丹下耕太、中井裕太、吉岡宏樹、秋田英万
- Organizer
  第24回日本がん免疫学会総会、2020年10月7-9日、ホテルライフォート札幌（北海道）（Web参加）、口頭発表
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 凍結乾燥を基盤とするmRNA内封脂質ナノ粒子Ready-to-Use製剤の創成2020
- Author(s)
  萩原伸哉、田中浩揮、白根大貴、高田奈依、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  日本薬剤学会　第35年会、熊本
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 抗腫瘍免疫の正常化を目的とした脾臓の炎症環境の改善：RISET療法の提唱2020
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  第24回日本がん免疫学会総会、2020年10月7-9日、ホテルライフォート札幌（北海道）（Web参加）、口頭発表
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of RNA vaccine platform based on environmentally-responsive and self-degradable lipid-like material with Vitamin E scaffold（ ssPalmE-Ph）2020
- Author(s)
  Jessica Anindita、田中浩揮、大山遼太郎、萩原伸哉、白根大貴、櫻井遊、玉川晋也、中井悠太、丹下耕太、秋田英万
- Organizer
  日本薬剤学会　第35年会、熊本
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 人工mRNAベクターを基盤とするT細胞エンジニアリング技術の開発2020
- Author(s)
  三山亮、田中浩揮、中井悠太、櫻井遊、玉川晋也、丹下耕太、秋田英万
- Organizer
  第43回日本分子生物学会、2020年12月2-4日、オンライン、ポスター発表
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 人工mRNAベクターを基盤とするT細胞エンジニアリング技術の開発2020
- Author(s)
  三山亮、田中浩揮、中井悠太、櫻井遊、玉川晋也、丹下耕太、秋田英万
- Organizer
  日本薬剤学会　第35年会、熊本
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 抗炎症薬搭載ナノ粒子による脾臓を標的とした新規がん治療戦略の開発2020
- Author(s)
  土井瑞貴、大東昂良、田中浩揮、三浦尚也、櫻井遊、秋田英万
- Organizer
  日本薬剤学会　第35年会、熊本
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of RNA vaccine platform based on environment-responsive materials for cancer immunotherapy2019
- Author(s)
  Anindita J, Tateshita N, Miura N, Tange K, Nakai Y, Yoshioka H, Tanaka H, Akita H.
- Organizer
  1st Chiba-Alberta Joint Symposium on Pharmaceutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 凍結乾燥ワンポット法を用いた核酸搭載型脂質ナノ粒子乾燥製剤の開発2019
- Author(s)
  白根大貴、田中浩揮、丹下耕太、中井悠太、吉岡宏樹、櫻井遊、秋田英万
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of DDS material and formulation technology that accelerates therapeutic application of mRNA2019
- Author(s)
  Hiroki Tanaka
- Organizer
  Dean's Grand Rounds Seminar, University of Alberta
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of RNA vaccine platform based on an intracellular environment-responsive lipid-like material with Vitamin E-scaffold2019
- Author(s)
  Oyama R, Tateshita N, Anindita J, Tanaka H, Miura N, Sakurai Y, Tange K, Nakai Y, Yoshioka H, Akita H
- Organizer
  Liposome Research Days 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Cytoplasmic delivery of exogenous IVT-mRNA using lipid-like material2019
- Author(s)
  Tanaka H, Konishi M, Takata N, Takahasi T, Nakai Y, Tange K, Yoshioka H, Tamagawa S, Akita H
- Organizer
  Liposome Research Days 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of freeze-dried formulation of RNA-loaded neutral lipid-nanoparticle based on pH-sensitive lipid-like material2019
- Author(s)
  Shirane D, Tanaka H, Tange K, Nakai Y, Yoshioka H, Sakurai Y, Akita H
- Organizer
  19th Symposium for Gene, Design and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of DNA/RNA vaccine platform based on an intracellular environment-responsive material (ssPalm) for cancer immune therapy2019
- Author(s)
  Tateshita N, Ohyama R, Anindita J, Tanaka H, Miura N, Nakai Y, Tange K, Yoshioka H, Tamagawa S, Sakurai Y, Akita H
- Organizer
  Lymphatic Forum 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of RNA carriers based on self-degradable materials2019
- Author(s)
  Tanaka H, Konishi M, Takata N, Takahashi T, Nakai Y, Tange K, Yoshioka H, Tamagawa N, Akita H
- Organizer
  1st Chiba-Alberta Joint Symposium on Pharmaceutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of RNA carriers based on self-degradable materials2019
- Author(s)
  Hiroki Tanaka, Manami Konishi, Nae Takata, Tatsunari Takahasi, Yuta Nakai, Kota Tange, Hiroki Yoshioka, Shinya Tamagawa, Hidetaka Akita
- Organizer
  1st Chiba-Alberta Joint Symposium on Pharmaceutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] ワンポット調製法を用いた siRNA 搭載型中性脂質ナノ粒子の開発2019
- Author(s)
  白根大貴, 田中浩揮, 吉岡宏樹, 丹下耕太, 中井悠太, 秋田英万
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Cytoplasmic delivery of exogenous IVT-mRNA using self-degradable lipid-like material2019
- Author(s)
  Tanaka H, Konishi M, Takata N, Takahasi T, Nakai Y, Tange K, Yoshioka H, Tamagawa S, Akita H
- Organizer
  7th International mRNA Health Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of RNA vaccine platform based on an intracellular environment-responsive lipid-like material with Vitamin E-scaffold2019
- Author(s)
  Oyama R, Tateshita N, Anindita J, Tanaka H, Miura N, Sakurai Y, Tange K, Nakai Y, Yoshioka H, Akita H
- Organizer
  19th Symposium for Gene, Design and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 自己分解性脂質様物質を用いたmRNAの肝臓導入と反復投与に関する検討2019
- Author(s)
  小西真奈美、田中浩揮、白根大貴、中井悠太、丹下耕太、玉川晋也、櫻井遊、秋田英万
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] ビタミンE足場型pH応答性脂質様材料を基盤とするmRNAワクチンの開発2019
- Author(s)
  大山遼太朗、舘下菜穂、Jessica Anindita、田中浩揮、三浦尚也、櫻井遊、丹下耕太、中井裕太、吉岡宏樹、秋田英万
- Organizer
  第25回創剤フォーラム若手研究会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 細胞内/粒子内環境に応答性を有する脂質様材料の分子設計と核酸キャリアの物性評価2019
- Author(s)
  田中浩揮, 中井悠太, 丹下耕太, 吉岡宏樹, 秋田英万
- Organizer
  日本薬学会　第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] ナノ粒子物性がリンパシステム内動態に及ぼす影響：リンパ流改変モデルマウスを用いた検証2019
- Author(s)
  五味昌樹、櫻井遊、田中浩揮、三浦尚哉、秋田新介、山路佳久、三科信之、秋田英万
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] COPD 根治治療薬としての Am80 封入 ssPalm ナノ粒子の有用性の検討2019
- Author(s)
  長島彰太, 加藤大貴, 三浦可南子, 秋田智后, 田中浩揮, 秋田英万,山下親正
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Development of self-hydrolyzable lipid-like material equipped with environment sensing motifs.2018
- Author(s)
  Tanaka H, Konishi M, Takata N, Takahashi T, Nakai Y, Yoshioka H, Akita H.
- Organizer
  18th Symposium for Gene, Design and Delivery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 凍結乾燥ワンポット法によるsiRNA 搭載型中性脂質ナノ粒子の開発と機能評価2018
- Author(s)
  白根大貴、田中浩揮、丹下耕太、中井悠太、吉岡宏樹、秋田英万
- Organizer
  第34回日本ＤＤＳ学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 還元環境依存的な粒子内分解機構を搭載した自己崩壊型RNA送達システムの開発2018
- Author(s)
  高田奈依、田中浩揮、高橋達成、小西真奈美、中井悠太、丹下耕太、吉岡宏樹、玉川晋也、秋田英万
- Organizer
  日本核酸医薬学会第4回年会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 細胞内環境応答性脂質様材料を基盤とするin vivoメッセンジャーRNA送達システムの開発2018
- Author(s)
  小西真奈美、田中浩揮、高橋達也、高田奈依、中井悠太、丹下耕太、吉岡宏樹、玉川晋也、秋田英万
- Organizer
  第12回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 環境応答性材料ssPalmを用いたmRNAキャリアの開発と癌免疫療法を目指したワクチン技術への応用2018
- Author(s)
  館下菜穂、三浦尚也、田中浩揮、中井悠太、吉岡宏樹、秋田英万
- Organizer
  第34回日本ＤＤＳ学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 細胞内における動態制御・崩壊を考慮した脂質様材料の開発とその物性および機能評価2018
- Author(s)
  秋田英万、田中浩揮
- Organizer
  日本薬学会第138年会　シンポジウム　「ナノＤＤＳ製剤の特性解析とその分析評価技術」　2018年3月28日　金沢市アートホール
- Invited
- Data Source
  KAKENHI-PROJECT-17H06558
[Presentation] 粒子内自己分解性脂質様材料の開発とmRNA送達への応用2018
- Author(s)
  高橋達成、田中浩揮、中井悠太、吉岡宏樹、秋田英万
- Organizer
  遺伝子・デリバリー研究会第18回夏期セミナー
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] ワンポット調製法を用いた siRNA 搭載型中性脂質ナノ粒子の開発2018
- Author(s)
  白根大貴, 田中浩揮, 吉岡宏樹, 丹下耕太, 中井悠太, 秋田英万
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H06558
[Presentation] リンパ流改変モデルマウスの開発およびナノ粒子の物性がリンパ節移行性に及ぼす影響の解析2018
- Author(s)
  五味昌樹、櫻井遊、田中浩揮、三浦尚也、秋田新介、山路佳久、三川信之、秋田英万
- Organizer
  遺伝子・デリバリー研究会第18回夏期セミナー
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 環境応答性脂質様材料を基盤とする外来mRNA導入技術の設計と開発2018
- Author(s)
  田中浩揮、秋田英万
- Organizer
  日本薬学会第138年会　シンポジウム　「人工RNAによる生体機能制御への挑戦」
- Invited
- Data Source
  KAKENHI-PROJECT-17H06558
[Presentation] 抗腫瘍免疫の正常化を目的とした脾臓および腫瘍組織における炎症環境の同時改善：がん治療における RISET 戦略の提唱2018
- Author(s)
  大東昂良、田中浩揮、土井瑞貴、三浦尚也、丹下耕太、中井悠太、吉岡宏樹、秋田英万
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] 環境応答性脂質様物質を用いた生体投与型mRNAデリバリーシステムの構築2018
- Author(s)
  田中浩揮、小西真奈美、高田奈江、高橋達成、中井悠太、丹下耕太、吉岡宏樹、玉川晋也、秋田英万
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-18K18377
[Presentation] Analysis of physicochemical properties of self-nanoemulsion constructed from environment sensitive ionizable lipid2017
- Author(s)
  Hiroki Tanaka, Sho Oasa, Masataka Kinjo, Kota Tange, Yuta Nakai, Hideyoshi Harashima, Hidetaka Akita
- Organizer
  FIP PSWC2017 6th Pharmaceutical Sciences World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06558
[Presentation] 炎症大腸を標的とした核酸封入型中性脂質ナノ粒子の創成2017
- Author(s)
  田中浩揮、渡邊綾香、丹下耕太、中井悠太、原島秀吉、秋田英万
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17H06558
[Presentation] 凍結乾燥技術を用いた中性脂質ナノ粒子のワンポット調製法の開発2017
- Author(s)
  白根大貴、田中浩揮、丹下耕太、中井悠太、秋田英万
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17H06558
[Presentation] 炎症大腸に対するナノ粒子核酸送達システムの開発2017
- Author(s)
  田中浩揮、渡辺綾香、丹下耕太、中井悠太、原島秀吉、秋田英万
- Organizer
  核酸医薬学会第 3 回年会
- Data Source
  KAKENHI-PROJECT-17H06558

1. Takanori Kanazawa (60434015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 小菅康弘 (70383726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 秋田英万 (80344472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
4. 櫻井遊 (00707234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
5. 松下博和 (80597782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 増田豪 (70383940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 澤村正典 (60852423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MORISHITA Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. OHKAWARA Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. TAKEDA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. HIGASHI Kenjirou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 亀井敬泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 森部久仁一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 植田圭祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 西川義文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 渡邉瑞貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Hiroki 田中 浩揮

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Development of "Immune Stealth LNP" for mRNA-based gene therapyPrincipal Investigator

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脳内病態伝播拠点標的RNA送達Nose-to-Brainミセル開発と脳神経ゲノム編集治療基盤構築

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Ready-tp-Use RNA-drug discovery for the acceleration of personalized cancer vaccine

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Development of immunosuppressive dendritic cells and autoimmune disease treatment based on mRNA delivery technologyPrincipal Investigator

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Development of nucleic acid delivery nano-DDS based on nose-to-brain route and its application to glia targeted therapy

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Development of self-degradable lipid like material based on intraparticle reactionPrincipal Investigator

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pH感受性脂質の分子改変による炎症組織の細胞内ポリソームを標的としたmRNA送達Principal Investigator

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[Book] mRNAを製造するための原料： 細胞内環境応答性脂質ナノ粒子によるDDS効果の向上（14章）2023

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[Book] 医薬品におけるDDS技術開発と製剤への応用（4章2節）2021

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[Book] 創薬研究者・アカデミア研究者が知っておくべき最新の免疫学とその応用技術（6章7節）2021

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[Journal Article] The Effect of Cholesterol Content on the Adjuvant Activity of Nucleic-Acid-Free Lipid Nanoparticles2024

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[Journal Article] Lymphatic Endothelial Cells Produce Chemokines in Response to the Lipid Nanoparticles Used in RNA Vaccines2024

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[Journal Article] An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses2023

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Tanaka Hiroki 田中浩揮

[Book] mRNAを製造するための原料：細胞内環境応答性脂質ナノ粒子によるDDS効果の向上（14章）2023