Tsubota (Hirano) Arisa 坪田有沙 (平野有沙)

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Tsubota Arisa 坪田有沙

平野有沙

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Researcher Number	60806230
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 助教
Affiliation (based on the past Project Information) *help	2018 – 2025: 筑波大学, 医学医療系, 助教 2017: 筑波大学, 国際統合睡眠医科学研究機構, 助教
Review Section/Research Field	Principal Investigator Complex systems / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 46030:Function of nervous system-related / Basic Section 43030:Functional biochemistry-related / Neurophysiology / General neuroscience Except Principal Investigator Transformative Research Areas, Section (III) / Biological Sciences
Keywords	Principal Investigator 概日時計 / 概日リズム / 視交叉上核 / 睡眠 / サーカディアンリズム / 視床下部 / 睡眠リズム / 体内時計 / 光遺伝学 / 低代謝 … More / QIH / 冬眠様行動 / 体温 / SCN / CRYPTOCHROME / 光受容 / 光受容体 / CRY / 神経ペプチド … More Except Principal Investigator 視交叉上核 / 記憶痕跡 / 海馬 / QIH / 概日リズム / 記憶 / 冬眠 / 創薬科学 / 脳機能 / 神経生物学 / 睡眠 Less

体温リズムを制御する神経メカニズムの解明Principal Investigator
- Principal Investigator
  
  坪田有沙 (平野有沙)
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  University of Tsukuba
低温状態での脳機能動態
- Principal Investigator
  
  田中和正
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
Deciphering the mysteries of sleep:creating a global network of sleep neurobiologists
- Principal Investigator
  
  柳沢正史
- Project Period (FY)
  2022 – 2028
- Research Category
  
  Fund for the Promotion of Joint International Research (International Leading Research )
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
冬眠様状態の脳における時の流れの研究Principal Investigator
- Principal Investigator
  
  坪田有沙 (平野有沙)
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  University of Tsukuba
Molecular and functional analysis of neural network of the circadian clockPrincipal Investigator
- Principal Investigator
  
  Hirano Arisa
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  University of Tsukuba
時刻依存的な睡眠パターンを形成する神経基盤の解明Principal Investigator
- Principal Investigator
  
  坪田有沙 (平野有沙)
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  University of Tsukuba
Functional analysis of mammalian CRY protein in photo-receptionPrincipal Investigator
- Principal Investigator
  
  Tsubota Arisa
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  University of Tsukuba
睡眠覚醒リズムを生み出す神経ネットワークの解明Principal Investigator
- Principal Investigator
  
  坪田有沙 (平野有沙)
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  University of Tsukuba

All 2024 2023 2022 2020 2018 2017

All Journal Article Presentation

[Journal Article] Crucial role of TFAP2B in the nervous system for regulating NREM sleep2024
- Author(s)
  Nakai Ayaka、Kashiwagi Mitsuaki、Fujiyama Tomoyuki、Iwasaki Kanako、Hirano Arisa、Funato Hiromasa、Yanagisawa Masashi、Sakurai Takeshi、Hayashi Yu
- Journal Title
  
  Molecular Brain
  
  Volume: 17 Issue: 1
- DOI
  10.1186/s13041-024-01084-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19354, KAKENHI-PUBLICLY-23H04210, KAKENHI-PUBLICLY-23H04668, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
[Journal Article] Analysis of circadian rhythm components in EEG/EMG data of aged mice.2023
- Author(s)
  Masuda K, Katsuda Y, Niwa Y, Sakurai T and Hirano A
- Journal Title
  
  Front. Neurosci.
  
  Volume: 17 Pages: 1173537-1173537
- DOI
  10.3389/fnins.2023.1173537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-22K15157, KAKENHI-PROJECT-22KJ0377, KAKENHI-PROJECT-20K07732, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04944
[Journal Article] Measuring body temperature of freely moving mice under optogenetics-induced long-term hypothermic state2023
- Author(s)
  Takahashi TM, Sakurai T, Hirano A
- Journal Title
  
  STAR Protocol
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00298
[Journal Article] SIK3-HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice2023
- Author(s)
  Asano Fuyuki、Kim Staci J.、Fujiyama Tomoyuki、Miyoshi Chika、Hotta-Hirashima Noriko、Asama Nodoka、Iwasaki Kanako、Kakizaki Miyo、Mizuno Seiya、Mieda Michihiro、Sugiyama Fumihiro、Takahashi Satoru、Shi Shoi、Hirano Arisa、Funato Hiromasa、Yanagisawa Masashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 11 Pages: 1-11
- DOI
  10.1073/pnas.2218209120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05985, KAKENHI-PROJECT-22K19410, KAKENHI-PROJECT-21K15004, KAKENHI-PROJECT-22H04918, KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-23K24064, KAKENHI-PLANNED-20H05903, KAKENHI-PROJECT-20H00567
[Journal Article] Structure and Function of Neuronal Circuits linking Ventrolateral Preoptic Nucleus and Lateral Hypothalamic Area.2023
- Author(s)
  Kseniia P, Saito YC, Niwa Y, Mizuno S, Takahashi S, Hirano A, Sakurai T
- Journal Title
  
  Journal of Neuroscience
  
  Volume: － Issue: 22 Pages: 4075-4092
- DOI
  10.1523/jneurosci.1913-22.2023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-20K07732, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
[Journal Article] Aripiprazole disrupts cellular synchrony in the suprachiasmatic nucleus and enhances entrainment to environmental light?dark cycles in mice2023
- Author(s)
  Li Ruoshi、Masuda Kosaku、Ono Daisuke、Kanbayashi Takashi、Hirano Arisa、Sakurai Takeshi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 17 Pages: 1201137-1201137
- DOI
  10.3389/fnins.2023.1201137
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15157, KAKENHI-PROJECT-22KJ0377, KAKENHI-PROJECT-22KJ0351, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
[Journal Article] Measuring body temperature of freely moving mice under an optogenetics-induced long-term hypothermic state2023
- Author(s)
  Takahashi Tohru M.、Sakurai Takeshi、Hirano Arisa
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 2 Pages: 102321-102321
- DOI
  10.1016/j.xpro.2023.102321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15219, KAKENHI-PROJECT-22KJ0373, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
[Journal Article] Singularity response reveals entrainment properties in mammalian circadian clock.2023
- Author(s)
  Masuda K, Kon N, Iizuka K, Fukada Y, Sakurai T, Hirano A
- Journal Title
  
  Nature Communications
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00298
[Journal Article] Singularity response reveals entrainment properties in mammalian circadian clock2023
- Author(s)
  Masuda Kosaku、Kon Naohiro、Iizuka Kosuke、Fukada Yoshitaka、Sakurai Takeshi、Hirano Arisa
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 2819-2819
- DOI
  10.1038/s41467-023-38392-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15157, KAKENHI-PROJECT-22KJ0377, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
[Journal Article] Editorial: The Role of Neuropeptides in Sleep/Wakefulness States and the Circadian Clock2022
- Author(s)
  Tsujino Natsuko、Ikeda Masayuki、Hirano Arisa、Sakurai Takeshi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 91337-91337
- DOI
  10.3389/fnins.2022.913371
- Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-20K15921
[Journal Article] Optogenetic induction of hibernation-like state with modified human Opsin4 in mice2022
- Author(s)
  Takahashi Tohru M.、Hirano Arisa、Kanda Takeshi、Saito Viviane M.、Ashitomi Hiroto、Tanaka Kazumasa Z.、Yokoshiki Yasufumi、Masuda Kosaku、Yanagisawa Masashi、Vogt Kaspar E.、Tokuda Takashi、Sakurai Takeshi
- Journal Title
  
  Cell Reports Methods
  
  Volume: 2 Issue: 11 Pages: 100336-100336
- DOI
  10.1016/j.crmeth.2022.100336
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06922, KAKENHI-PROJECT-22K15219, KAKENHI-PROJECT-22H04918, KAKENHI-PROJECT-21H02585, KAKENHI-PROJECT-22KJ0373, KAKENHI-PROJECT-21K19287, KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-21H05036
[Journal Article] A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice2020
- Author(s)
  Shuntaro Uchida, Shingo Soya, Yuki C Saito, Arisa Hirano, Keisuke Koga, Makoto Tsuda, Manabu Abe, Kenji Sakimura, Takeshi Sakurai
- Journal Title
  
  journal of neuroscience
  
  Volume: 41 Issue: 7 Pages: 1582-1596
- DOI
  10.1523/jneurosci.0688-20.2020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15921, KAKENHI-PROJECT-20K16133, KAKENHI-ORGANIZER-16H06400, KAKENHI-PLANNED-16H06401, KAKENHI-PUBLICLY-19H04894, KAKENHI-PUBLICLY-19H05305, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02595, KAKENHI-PROJECT-18J21114
[Journal Article] DEC2 modulates orexin expression and regulates sleep.2018
- Author(s)
  Hirano A, Hsu PK, Zhang L, Xing L, McMahon T, Yamazaki M, Ptacek LJ, Fu YH.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 115 Issue: 13 Pages: 3434-3439
- DOI
  10.1073/pnas.1801693115
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06546
[Journal Article] FAD Regulates CRYPTOCHROME Protein Stability and Circadian Clock in Mice.2017
- Author(s)
  Hirano A, Braas D, Fu YH, Ptacek LJ.
- Journal Title
  
  Cell Reports
  
  Volume: 19 Issue: 2 Pages: 255-266
- DOI
  10.1016/j.celrep.2017.03.041
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06546
[Journal Article] Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein2017
- Author(s)
  Naoto Hayasaka, Arisa Hirano, Yuka Miyoshi, Isao T. Tokuda, Hikari Yoshitane, Junichiro Matsuda, Yoshitaka Fukada
- Journal Title
  
  eLife
  
  Volume: 6
- DOI
  10.7554/elife.24779
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00343, KAKENHI-PROJECT-26286086, KAKENHI-PROJECT-17H06546, KAKENHI-PROJECT-17H06096, KAKENHI-PROJECT-15K15040
[Presentation] Projection mapping of SCN neurons and its functional analysis.2020
- Author(s)
  Arisa Hirano, Yuki Saito, Takeshi Sakurai
- Organizer
  第27回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05305
[Presentation] Neural circuit of circadian sleep regulation in mice.2020
- Author(s)
  Arisa Hirano, Yuki Saito, Takeshi Sakurai
- Organizer
  第43回日本神経科学大会（招待講演）
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05305
[Presentation] Neural circuit of circadian sleep regulation in mice2020
- Author(s)
  Arisa Hirano, Yuki Saito, Takeshi Sakurai
- Organizer
  第43回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K15921
[Presentation] Function of CRY in photo-sensing in mouse retina2020
- Author(s)
  Arisa Hirano
- Organizer
  Society for research on biological rhythms, 2020 meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H05305
[Presentation] Function of CRY in photo-sensing in mouse retina2020
- Author(s)
  Arisa Hirano
- Organizer
  Society for research on biological rhythms, 2020 meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14646
[Presentation] Projection mapping of SCN neurons and its functional analysis2020
- Author(s)
  Arisa Hirano, Yuki Saito, Takeshi Sakurai
- Organizer
  第27回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K15921
[Presentation] Function of CRY in photo-sensing in mouse retina2020
- Author(s)
  Arisa Hirano
- Organizer
  Society for research on biological rhythms, 2020 meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15921

1. 柳沢正史 (20202369)

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2. 阿部高志 (00549644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 本城咲季子 (30551379)

# of Collaborated Projects: 1 results

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4. 林悠 (40525812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 史蕭逸 (40803656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 桜井武 (60251055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 坂口昌徳 (60407088)

# of Collaborated Projects: 1 results

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8. ラザルスミハエル (80469650)

# of Collaborated Projects: 1 results

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9. 斉藤毅 (80609933)

# of Collaborated Projects: 1 results

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10. Vogt Kaspar (80740034)

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11. 田中和正 (10772650)

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12. FUNATO Hiromasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 三好千香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 上田壮志

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# of Collaborated Products: 1 results
15. 増田亘作

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# of Collaborated Products: 2 results
16. 高橋徹

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# of Collaborated Products: 1 results
17. 徳田功

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# of Collaborated Products: 1 results

Tsubota (Hirano) Arisa 坪田 有沙 (平野 有沙)

Tsubota Arisa 坪田 有沙

平野 有沙

平野有沙

Research Projects

Research Products

Co-Researchers

体温リズムを制御する神経メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

低温状態での脳機能動態

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Deciphering the mysteries of sleep:creating a global network of sleep neurobiologists

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

冬眠様状態の脳における時の流れの研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular and functional analysis of neural network of the circadian clockPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

時刻依存的な睡眠パターンを形成する神経基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of mammalian CRY protein in photo-receptionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

睡眠覚醒リズムを生み出す神経ネットワークの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Crucial role of TFAP2B in the nervous system for regulating NREM sleep2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of circadian rhythm components in EEG/EMG data of aged mice.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Measuring body temperature of freely moving mice under optogenetics-induced long-term hypothermic state2023

Author(s)

Journal Title

Data Source

[Journal Article] SIK3-HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure and Function of Neuronal Circuits linking Ventrolateral Preoptic Nucleus and Lateral Hypothalamic Area.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aripiprazole disrupts cellular synchrony in the suprachiasmatic nucleus and enhances entrainment to environmental light?dark cycles in mice2023

Tsubota (Hirano) Arisa 坪田有沙 (平野有沙)

Tsubota Arisa 坪田有沙

平野有沙