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Tsubota (Hirano) Arisa  坪田 有沙 (平野 有沙)

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Tsubota Arisa  坪田 有沙

平野 有沙

平野有沙

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Researcher Number 60806230
Other IDs
Affiliation (Current) 2025: 筑波大学, 医学医療系, 助教
Affiliation (based on the past Project Information) *help 2018 – 2025: 筑波大学, 医学医療系, 助教
2017: 筑波大学, 国際統合睡眠医科学研究機構, 助教
Review Section/Research Field
Principal Investigator
Complex systems / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 46030:Function of nervous system-related / Basic Section 43030:Functional biochemistry-related / Neurophysiology / General neuroscience
Except Principal Investigator
Transformative Research Areas, Section (III) / Biological Sciences
Keywords
Principal Investigator
概日時計 / 概日リズム / 視交叉上核 / 睡眠 / サーカディアンリズム / 視床下部 / 睡眠リズム / 体内時計 / 光遺伝学 / 低代謝 … More / QIH / 冬眠様行動 / 体温 / SCN / CRYPTOCHROME / 光受容 / 光受容体 / CRY / 神経ペプチド … More
Except Principal Investigator
視交叉上核 / 記憶痕跡 / 海馬 / QIH / 概日リズム / 記憶 / 冬眠 / 創薬科学 / 脳機能 / 神経生物学 / 睡眠 Less
  • Research Projects

    (8 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (17 People)
  •  体温リズムを制御する神経メカニズムの解明Principal Investigator

    • Principal Investigator
      坪田 有沙 (平野 有沙)
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      University of Tsukuba
  •  低温状態での脳機能動態

    • Principal Investigator
      田中 和正
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Okinawa Institute of Science and Technology Graduate University
  •  Deciphering the mysteries of sleep:creating a global network of sleep neurobiologists

    • Principal Investigator
      柳沢 正史
    • Project Period (FY)
      2022 – 2028
    • Research Category
      Fund for the Promotion of Joint International Research (International Leading Research )
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  冬眠様状態の脳における時の流れの研究Principal Investigator

    • Principal Investigator
      坪田 有沙 (平野有沙)
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      University of Tsukuba
  •  Molecular and functional analysis of neural network of the circadian clockPrincipal Investigator

    • Principal Investigator
      Hirano Arisa
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 46030:Function of nervous system-related
    • Research Institution
      University of Tsukuba
  •  時刻依存的な睡眠パターンを形成する神経基盤の解明Principal Investigator

    • Principal Investigator
      坪田 有沙 (平野有沙)
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      University of Tsukuba
  •  Functional analysis of mammalian CRY protein in photo-receptionPrincipal Investigator

    • Principal Investigator
      Tsubota Arisa
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      University of Tsukuba
  •  睡眠覚醒リズムを生み出す神経ネットワークの解明Principal Investigator

    • Principal Investigator
      坪田 有沙 (平野有沙)
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      University of Tsukuba

All 2024 2023 2022 2020 2018 2017

All Journal Article Presentation

  • [Journal Article] Crucial role of TFAP2B in the nervous system for regulating NREM sleep2024

    • Author(s)
      Nakai Ayaka、Kashiwagi Mitsuaki、Fujiyama Tomoyuki、Iwasaki Kanako、Hirano Arisa、Funato Hiromasa、Yanagisawa Masashi、Sakurai Takeshi、Hayashi Yu
    • Journal Title

      Molecular Brain

      Volume: 17 Issue: 1

    • DOI

      10.1186/s13041-024-01084-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19354, KAKENHI-PUBLICLY-23H04210, KAKENHI-PUBLICLY-23H04668, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
  • [Journal Article] Analysis of circadian rhythm components in EEG/EMG data of aged mice.2023

    • Author(s)
      Masuda K, Katsuda Y, Niwa Y, Sakurai T and Hirano A
    • Journal Title

      Front. Neurosci.

      Volume: 17 Pages: 1173537-1173537

    • DOI

      10.3389/fnins.2023.1173537

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-22K15157, KAKENHI-PROJECT-22KJ0377, KAKENHI-PROJECT-20K07732, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04944
  • [Journal Article] Measuring body temperature of freely moving mice under optogenetics-induced long-term hypothermic state2023

    • Author(s)
      Takahashi TM, Sakurai T, Hirano A
    • Journal Title

      STAR Protocol

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H00298
  • [Journal Article] SIK3-HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice2023

    • Author(s)
      Asano Fuyuki、Kim Staci J.、Fujiyama Tomoyuki、Miyoshi Chika、Hotta-Hirashima Noriko、Asama Nodoka、Iwasaki Kanako、Kakizaki Miyo、Mizuno Seiya、Mieda Michihiro、Sugiyama Fumihiro、Takahashi Satoru、Shi Shoi、Hirano Arisa、Funato Hiromasa、Yanagisawa Masashi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 120 Issue: 11 Pages: 1-11

    • DOI

      10.1073/pnas.2218209120

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K05985, KAKENHI-PROJECT-22K19410, KAKENHI-PROJECT-21K15004, KAKENHI-PROJECT-22H04918, KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-23K24064, KAKENHI-PLANNED-20H05903, KAKENHI-PROJECT-20H00567
  • [Journal Article] Structure and Function of Neuronal Circuits linking Ventrolateral Preoptic Nucleus and Lateral Hypothalamic Area.2023

    • Author(s)
      Kseniia P, Saito YC, Niwa Y, Mizuno S, Takahashi S, Hirano A, Sakurai T
    • Journal Title

      Journal of Neuroscience

      Volume: - Issue: 22 Pages: 4075-4092

    • DOI

      10.1523/jneurosci.1913-22.2023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-20K07732, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
  • [Journal Article] Aripiprazole disrupts cellular synchrony in the suprachiasmatic nucleus and enhances entrainment to environmental light?dark cycles in mice2023

    • Author(s)
      Li Ruoshi、Masuda Kosaku、Ono Daisuke、Kanbayashi Takashi、Hirano Arisa、Sakurai Takeshi
    • Journal Title

      Frontiers in Neuroscience

      Volume: 17 Pages: 1201137-1201137

    • DOI

      10.3389/fnins.2023.1201137

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15157, KAKENHI-PROJECT-22KJ0377, KAKENHI-PROJECT-22KJ0351, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
  • [Journal Article] Measuring body temperature of freely moving mice under an optogenetics-induced long-term hypothermic state2023

    • Author(s)
      Takahashi Tohru M.、Sakurai Takeshi、Hirano Arisa
    • Journal Title

      STAR Protocols

      Volume: 4 Issue: 2 Pages: 102321-102321

    • DOI

      10.1016/j.xpro.2023.102321

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15219, KAKENHI-PROJECT-22KJ0373, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
  • [Journal Article] Singularity response reveals entrainment properties in mammalian circadian clock.2023

    • Author(s)
      Masuda K, Kon N, Iizuka K, Fukada Y, Sakurai T, Hirano A
    • Journal Title

      Nature Communications

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H00298
  • [Journal Article] Singularity response reveals entrainment properties in mammalian circadian clock2023

    • Author(s)
      Masuda Kosaku、Kon Naohiro、Iizuka Kosuke、Fukada Yoshitaka、Sakurai Takeshi、Hirano Arisa
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 2819-2819

    • DOI

      10.1038/s41467-023-38392-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15157, KAKENHI-PROJECT-22KJ0377, KAKENHI-ORGANIZER-23H04939, KAKENHI-PLANNED-23H04941, KAKENHI-PLANNED-23H04944, KAKENHI-PROJECT-21H05036
  • [Journal Article] Editorial: The Role of Neuropeptides in Sleep/Wakefulness States and the Circadian Clock2022

    • Author(s)
      Tsujino Natsuko、Ikeda Masayuki、Hirano Arisa、Sakurai Takeshi
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 91337-91337

    • DOI

      10.3389/fnins.2022.913371

    • Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-20K15921
  • [Journal Article] Optogenetic induction of hibernation-like state with modified human Opsin4 in mice2022

    • Author(s)
      Takahashi Tohru M.、Hirano Arisa、Kanda Takeshi、Saito Viviane M.、Ashitomi Hiroto、Tanaka Kazumasa Z.、Yokoshiki Yasufumi、Masuda Kosaku、Yanagisawa Masashi、Vogt Kaspar E.、Tokuda Takashi、Sakurai Takeshi
    • Journal Title

      Cell Reports Methods

      Volume: 2 Issue: 11 Pages: 100336-100336

    • DOI

      10.1016/j.crmeth.2022.100336

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06922, KAKENHI-PROJECT-22K15219, KAKENHI-PROJECT-22H04918, KAKENHI-PROJECT-21H02585, KAKENHI-PROJECT-22KJ0373, KAKENHI-PROJECT-21K19287, KAKENHI-PUBLICLY-21H00298, KAKENHI-PROJECT-21H05036
  • [Journal Article] A Discrete Glycinergic Neuronal Population in the Ventromedial Medulla That Induces Muscle Atonia during REM Sleep and Cataplexy in Mice2020

    • Author(s)
      Shuntaro Uchida, Shingo Soya, Yuki C Saito, Arisa Hirano, Keisuke Koga, Makoto Tsuda, Manabu Abe, Kenji Sakimura, Takeshi Sakurai
    • Journal Title

      journal of neuroscience

      Volume: 41 Issue: 7 Pages: 1582-1596

    • DOI

      10.1523/jneurosci.0688-20.2020

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K15921, KAKENHI-PROJECT-20K16133, KAKENHI-ORGANIZER-16H06400, KAKENHI-PLANNED-16H06401, KAKENHI-PUBLICLY-19H04894, KAKENHI-PUBLICLY-19H05305, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02595, KAKENHI-PROJECT-18J21114
  • [Journal Article] DEC2 modulates orexin expression and regulates sleep.2018

    • Author(s)
      Hirano A, Hsu PK, Zhang L, Xing L, McMahon T, Yamazaki M, Ptacek LJ, Fu YH.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 115 Issue: 13 Pages: 3434-3439

    • DOI

      10.1073/pnas.1801693115

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06546
  • [Journal Article] FAD Regulates CRYPTOCHROME Protein Stability and Circadian Clock in Mice.2017

    • Author(s)
      Hirano A, Braas D, Fu YH, Ptacek LJ.
    • Journal Title

      Cell Reports

      Volume: 19 Issue: 2 Pages: 255-266

    • DOI

      10.1016/j.celrep.2017.03.041

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06546
  • [Journal Article] Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein2017

    • Author(s)
      Naoto Hayasaka, Arisa Hirano, Yuka Miyoshi, Isao T. Tokuda, Hikari Yoshitane, Junichiro Matsuda, Yoshitaka Fukada
    • Journal Title

      eLife

      Volume: 6

    • DOI

      10.7554/elife.24779

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K00343, KAKENHI-PROJECT-26286086, KAKENHI-PROJECT-17H06546, KAKENHI-PROJECT-17H06096, KAKENHI-PROJECT-15K15040
  • [Presentation] Projection mapping of SCN neurons and its functional analysis.2020

    • Author(s)
      Arisa Hirano, Yuki Saito, Takeshi Sakurai
    • Organizer
      第27回日本時間生物学会学術大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H05305
  • [Presentation] Neural circuit of circadian sleep regulation in mice.2020

    • Author(s)
      Arisa Hirano, Yuki Saito, Takeshi Sakurai
    • Organizer
      第43回日本神経科学大会(招待講演)
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-19H05305
  • [Presentation] Neural circuit of circadian sleep regulation in mice2020

    • Author(s)
      Arisa Hirano, Yuki Saito, Takeshi Sakurai
    • Organizer
      第43回日本神経科学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K15921
  • [Presentation] Function of CRY in photo-sensing in mouse retina2020

    • Author(s)
      Arisa Hirano
    • Organizer
      Society for research on biological rhythms, 2020 meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H05305
  • [Presentation] Function of CRY in photo-sensing in mouse retina2020

    • Author(s)
      Arisa Hirano
    • Organizer
      Society for research on biological rhythms, 2020 meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14646
  • [Presentation] Projection mapping of SCN neurons and its functional analysis2020

    • Author(s)
      Arisa Hirano, Yuki Saito, Takeshi Sakurai
    • Organizer
      第27回日本時間生物学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K15921
  • [Presentation] Function of CRY in photo-sensing in mouse retina2020

    • Author(s)
      Arisa Hirano
    • Organizer
      Society for research on biological rhythms, 2020 meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K15921
  • 1.  柳沢 正史 (20202369)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  阿部 高志 (00549644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  本城 咲季子 (30551379)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  林 悠 (40525812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  史 蕭逸 (40803656)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  桜井 武 (60251055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  坂口 昌徳 (60407088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ラザルス ミハエル (80469650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  斉藤 毅 (80609933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Vogt Kaspar (80740034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  田中 和正 (10772650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  FUNATO Hiromasa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  三好 千香
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  上田 壮志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  増田 亘作
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 16.  高橋 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  徳田 功
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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