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Sakamoto Tatsuhiro  坂本 竜弘

Researcher Number 60815398
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-6852-0721
Affiliation (Current) 2022: 筑波大学, 医学医療系, 講師
Affiliation (based on the past Project Information) *help 2021 – 2022: 筑波大学, 医学医療系, 講師
2018 – 2020: 筑波大学, 附属病院, 病院講師
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related
Except Principal Investigator
Basic Section 52010:General internal medicine-related / Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
骨髄微小環境 / 赤血球造血 / Nestin陽性細胞 / Notchシグナル / IL-6 / 局所炎症 / 造血微小環境 / 赤芽球分化 / マクロファージ / Nestin陽性間葉系細胞 … More / 赤芽球造血 / 間葉系幹細胞 / 急性骨髄性白血病 / 治療反応性 / 再発 / 非腫瘍細胞 / 相互作用 … More
Except Principal Investigator
HEV / 血小板輸血 / 輸血関連感染症 / 造血細胞移植 / HEV感染 / 輸血用血液製剤 / 細菌感染 / 血液製剤汚染 / 血小板濃厚液 / HTLV-I / 輸血 / 輸血感染症 / 造血幹細胞 / 血小板 Less
  • Research Projects

    (4 results)
  • Research Products

    (20 results)
  • Co-Researchers

    (19 People)
  •  ヒト造血幹細胞の不均一性の解明と機能制御

    • Principal Investigator
      錦井 秀和
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      University of Tsukuba
  •  急性骨髄性白血病において非腫瘍細胞が果たす役割の解明Principal Investigator

    • Principal Investigator
      坂本 竜弘
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      University of Tsukuba
  •  A pilot study for transfusion related new infection research

    • Principal Investigator
      長谷川 雄一
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      University of Tsukuba
  •  Role of bone marrow microenvironment for erythropoiesisPrincipal Investigator

    • Principal Investigator
      Sakamoto Tatsuhiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      University of Tsukuba

All 2022 2021 2020 2019 2018

All Journal Article Presentation Book

  • [Book] The Peripheral T‐Cell Lymphomas2021

    • Author(s)
      Tatsuhiro Sakamoto, Mamiko Sakata-Yanagimoto, Owen A. O'Connor M.D., Ph.D.,Won Seog KimPier Luigi Zinzani M.D., Ph.D., et al.
    • Total Pages
      392
    • Publisher
      WILEY
    • ISBN
      9781119671312
    • Data Source
      KAKENHI-PROJECT-18K16107
  • [Journal Article] Salvage Cord Blood Transplantation Using a Short-term Reduced-intensity Conditioning Regimen for Graft Failure2022

    • Author(s)
      Suma Sakurako、Yokoyama Yasuhisa、Momose Haruka、Makishima Kenichi、Kiyoki Yusuke、Sakamoto Tatsuhiro、Kusakabe Manabu、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Internal Medicine

      Volume: 60 Issue: 11 Pages: 1673-1679

    • DOI

      10.2169/internalmedicine.7836-21

    • NAID

      130008119247

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16261
  • [Journal Article] A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodelling2022

    • Author(s)
      Abe Y, Sakata-Yanagimoto M, Fujisawa M, Miyoshi H, Suehara Y, Hattori K, Kusakabe M, Sakamoto T, Nishikii H, Nguyen TB, Owada Y, Enomoto T, Sawa A, Bando H, Yoshida C, Tabata R, Terao T, Nakayama M, Ohshima K, Usuki K, Oda T, Matsue K, Chiba S
    • Journal Title

      Nature Cell Biology

      Volume: 24 Pages: 565-578

    • DOI

      10.1038/s41556-022-00866-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-21K16261
  • [Journal Article] Early administration of cyclosporine may reduce the incidence of cytokine release syndrome after HLA-haploidentical hematopoietic stem-cell transplantation with post-transplant cyclophosphamide2021

    • Author(s)
      Kurita Naoki、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Yokoyama Yasuhisa、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Annals of Hematology

      Volume: 100 Pages: 1295-1301

    • DOI

      10.1007/s00277-021-04439-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-20K08725, KAKENHI-PROJECT-21K08365, KAKENHI-PROJECT-21K16261
  • [Journal Article] Tet2 deficiency in immune cells exacerbates tumor progression by increasing angiogenesis in a lung cancer model2021

    • Author(s)
      Nguyen YTM, Fujisawa M, Nguyen TB, Suehara Y, Tatsuhiro S, Matsuoka R, Abe Y, Fukumoto K, Hattori K, Noguchi M, Matsubara D, Chiba S, Sakata-Yanagimoto M.
    • Journal Title

      Cancer Science

      Volume: 112 Pages: 4931-4943

    • DOI

      10.1111/cas.15165

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17820, KAKENHI-PROJECT-21K16261
  • [Journal Article] Haploidentical transplantation from a related donor as first-line treatment for fulminant aplastic anemia2020

    • Author(s)
      槇島 健一、長谷川 雄一、千葉 滋、小原 直、坂本 竜弘、加藤 貴康、日下部 学、錦井 秀和、栗田 尚樹、横山 泰久、坂田(柳元) 麻実子
    • Journal Title

      Jpn. J. Clin. Hematol.

      Volume: 61 Issue: 10 Pages: 1464-1468

    • DOI

      10.11406/rinketsu.61.1464

    • NAID

      130007937040

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16107
  • [Journal Article] VAV1 mutations contribute to development of T-cell neoplasms in mice2020

    • Author(s)
      Fukumoto Kota、Sakata-Yanagimoto Mamiko、Fujisawa Manabu、Sakamoto Tatsuhiro、Miyoshi Hiroaki、Suehara Yasuhito、Nguyen Tran B.、Suma Sakurako、Yanagimoto Shintaro、Shiraishi Yuichi、Chiba Kenichi、Bouska Alyssa、Kataoka Keisuke、Ogawa Seishi、Iqbal Javeed、Ohshima Koichi、Chiba Shigeru
    • Journal Title

      Blood

      Volume: 136 Pages: 3018-3032

    • DOI

      10.1182/blood.2020006513

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19J11329, KAKENHI-PROJECT-18K16107
  • [Journal Article] Philadelphia chromosome-positive acute lymphoblastic leukemia complicated by bone marrow necrosis during consolidation chemotherapy2020

    • Author(s)
      石塚 幹太郎、錦井 秀和、横山 泰久、坂田(柳元) 麻実子、長谷川 雄一、品川 篤司、千葉 滋、小原 直、周山 拓也、松岡 亮太、丸山 ゆみ子、坂本 竜弘、日下部 学、加藤 貴康、栗田 尚樹
    • Journal Title

      Jpn. J. Clin. Hematol.

      Volume: 61 Issue: 5 Pages: 462-467

    • DOI

      10.11406/rinketsu.61.462

    • NAID

      130007852244

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16165, KAKENHI-PROJECT-18K16107
  • [Journal Article] Durable Leukemic Remission and Autologous Marrow Recovery with Random Chromosomal Abnormalities after Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia.2019

    • Author(s)
      Nishikii Hidekazu、Kurita Naoki、Shinagawa Atsushi、Sakamoto Tatsuhiro、Kusakabe Manabu、Yokoyama Yasuhisa、Kato Takayasu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Nakamura Naoya、Chiba Shigeru
    • Journal Title

      Case Report in Hematology

      Volume: 2019 Pages: 1-5

    • DOI

      10.1155/2019/9710790

    • NAID

      120007128070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K08316, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09946
  • [Journal Article] The prognosis of disseminated intravascular coagulation associated with hematologic malignancy and its response to recombinant human thrombomodulin.2019

    • Author(s)
      Kurita Naoki、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Yokoyama Yasuhisa、Nishikii Hidekazu、Sakata-Yanagimoto Mamiko、Obara Naoshi、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Thromb Res

      Volume: 173 Pages: 57-64

    • DOI

      10.1016/j.thromres.2018.11.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K09946
  • [Journal Article] Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis.2019

    • Author(s)
      Cao-Sy Luan、Obara Naoshi、Sakamoto Tatsuhiro、Kato Takayasu、Hattori Keiichiro、Sakashita Shingo、Nannya Yasuhito、Ogawa Seishi、Harada Hironori、Sakata-Yanagimoto Mamiko、Nishikii Hidekazu、Chiba Shigeru
    • Journal Title

      Int J Hematol

      Volume: 109 Pages: 309-318

    • DOI

      10.1007/s12185-018-02576-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-16K09831, KAKENHI-PROJECT-18K08316, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656
  • [Journal Article] High efficacy of eculizumab treatment for fulminant hemolytic anemia in primary cold agglutinin disease.2019

    • Author(s)
      Makishima Kenichi、Obara Naoshi、Ishitsuka Kantaro、Sukegawa Shinichiro、Suma Sakurako、Kiyoki Yusuke、Baba Naoko、Sakamoto Tatsuhiro、Kato Takayasu、Kusakabe Manabu、Nishikii Hidekazu、Kurita Naoki、Yokoyama Yasuhisa、Sakata-Yanagimoto Mamiko、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Ann Hematol

      Volume: 98 Pages: 1031-1032

    • DOI

      10.1007/s00277-018-3521-4

    • NAID

      120007128039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09898
  • [Journal Article] Notch signaling in Nestin-expressing cells in the bone marrow maintains erythropoiesis via macrophage integrity.2019

    • Author(s)
      Sakamoto Tatsuhiro、Obara Naoshi、Nishikii Hidekazu、Kato Takayasu、Luan Cao Sy、Fujimura Ryosuke、Yagita Hideo、Sakata-Yanagimoto Mamiko、Takahashi Satoru、Chiba Shigeru
    • Journal Title

      Stem cells

      Volume: 印刷中 Pages: 924-936

    • DOI

      10.1002/stem.3011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K08316, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-17K09915
  • [Journal Article] An Unprecedented Case of p190 BCR-ABL Chronic Myeloid Leukemia Diagnosed during Treatment for Multiple Myeloma: A Case Report and Review of the Literature2018

    • Author(s)
      Miki Kosuke、Obara Naoshi、Makishima Kenichi、Sakamoto Tatsuhiro、Kusakabe Manabu、Kato Takayasu、Kurita Naoki、Nishikii Hidekazu、Yokoyama Yasuhisa、Sakata-Yanagimoto Mamiko、Hasegawa Yuichi、Chiba Shigeru
    • Journal Title

      Case Reports in Hematology

      Volume: 2018 Pages: 1-5

    • DOI

      10.1155/2018/7863943

    • NAID

      120007128268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107
  • [Journal Article] Liquid biopsy for the identification of intravascular large B-cell lymphoma2018

    • Author(s)
      Suehara Yasuhito、Sakata-Yanagimoto Mamiko、et al
    • Journal Title

      Haematologica

      Volume: in press

    • DOI

      10.3324/haematol.2017.178830

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K15497, KAKENHI-PROJECT-17K09898, KAKENHI-PROJECT-17K09946, KAKENHI-PROJECT-18K07436, KAKENHI-PROJECT-18K16076, KAKENHI-PROJECT-18K16107, KAKENHI-PROJECT-16H02660
  • [Presentation] トロンボポエチン受容体作動薬治療を受けた再生不良性貧血患者の骨髄細胞における遺伝子変異の検討2021

    • Author(s)
      Tatsuhiro Sakamoto, Naoshi Obara, Yasuhito Nannya, Manabu Kusakabe1), Takayasu Kato1), Naoki Kurita1), Yasuhisa Yokoyama, Hidekazu Nishikii, Mamiko Sakata-Yanagimoto, Yuichi Hasegawa, Shigeru Chiba
    • Organizer
      第82回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K16107
  • [Presentation] Notch signaling in nestin-expressing bone marrow stromal cells supports erythropoietic niche2019

    • Author(s)
      Tatsuhiro Sakamoto
    • Organizer
      The 10th JSH INTERNATIONAL SYMPOSIUM
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16107
  • [Presentation] Impairment of bone marrow erythropoiesis is induced by disruption of Notch signaling in specific bone marrow microenvironment2018

    • Author(s)
      Tatsuhiro Sakamoto , Naoshi Obara , Hidekazu Nishikii , Takayasu Kato , Ryosuke Fujimura , Luan Cao Sy , Mamiko Sakata-Yanagimoto , Satoru Takahashi , Shigeru Chiba
    • Organizer
      The 16th Stem Cell Research Symposium
    • Data Source
      KAKENHI-PROJECT-18K16107
  • [Presentation] BONE MARROW ERYTHROPOIETIC DEFECT ACCOMPANYING EXTRAMEDULLARY HEMATOPOIESIS IS MIMICKED BY DOWNREGULATION OF NOTCH SIGNALING IN SPECIFIC MICROENVIRONMENT.2018

    • Author(s)
      Tatsuhiro Sakamoto , Naoshi Obara , Hidekazu Nishikii , Takayasu Kato , Ryosuke Fujimura , Luan Cao Sy , Mamiko Sakata-Yanagimoto , Satoru Takahashi , Shigeru Chiba
    • Organizer
      23rd Congress of EHA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16107
  • [Presentation] Bone Marrow Erythropoiesis is Maintained by Notch Signaling in Specific Bone Marrow Microenvironment2018

    • Author(s)
      Tatsuhiro Sakamoto , Naoshi Obara , Hidekazu Nishikii , Takayasu Kato , Ryosuke Fujimura , Luan Cao Sy , Mamiko Sakata-Yanagimoto , Satoru Takahashi , Shigeru Chiba
    • Organizer
      The 9th JSH International Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16107
  • 1.  長谷川 雄一 (00251059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  加藤 貴康 (20646591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  錦井 秀和 (30512834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  須藤 和寛 (10392002)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  山崎 聡 (50625580)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YOKOYAMA Yasuhisa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  KURITA Naoki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 8.  Sato Aiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  Chiba Shigeru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 10.  HARADA Yuka
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  NANYA Yasuhito
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  Hattori Keichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  小川 誠司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 14.  片岡 竜貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  小原 直
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 9 results
  • 16.  日下部 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 17.  原田 浩徳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  松岡 亮太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  坂田 麻実子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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