Ozaka Sotaro 小坂聡太郎

Researcher Number	60835700
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2022 – 2023: 大分大学, 医学部, 助教 2020 – 2021: 大分大学, 医学部, 医員
Review Section/Research Field	Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 47050:Environmental and natural pharmaceutical resources-related Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 炎症性腸疾患 / SLPI / バイオマーカー / 腸炎 / DSS腸炎 / 漢方薬 / 大建中湯 Except Principal Investigator 遺伝子欠損マウス / 腸炎 / 感染性腸炎 … More / 疾患モデルマウス / ゲノム編集マウス / CCR6 / CCR2 / ケモカイン受容体 / Th17細胞 / 炎症性腸疾患 Less

炎症性腸疾患におけるSLPIの新規バイオマーカーとしての可能性と有用性の検討Principal Investigator
- Principal Investigator
  
  小坂聡太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Oita University
Elucidation of the pathophysiology of colitis in CCR-deficient mice and establishment of a functional classification method for intestinal Th17 cells.
- Principal Investigator
  
  Kobayashi Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Oita University
The functional analysis of antimicrobial peptide SLPI in the intestine and a colon protective effect of DaikenchutoPrincipal Investigator
- Principal Investigator
  
  Ozaka Sotaro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Oita University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] 国民の栄養白書　2021年度版　日本の食と栄養が創る　新時代の健康第1部日本人と食のチカラ第2章日本人の身体に合った食事～腸内環境から考える日本人の理想の食～2022
- Author(s)
  小坂聡太郎, 小林隆志
- Total Pages
  193
- Publisher
  日本医療企画
- Data Source
  KAKENHI-PROJECT-21K07984
[Book] 国民の栄養白書2021年度版2021
- Author(s)
  小坂聡太郎, 小林隆志
- Total Pages
  204
- Publisher
  日本医療企画
- ISBN
  9784867290811
- Data Source
  KAKENHI-PROJECT-20K16028
[Book] 消化性潰瘍診療ガイドライン2020改訂第3版2020
- Author(s)
  小池和彦，渡辺純夫，佐藤貴一，鎌田智有，伊藤俊之，伊藤公訓，岩本淳一，沖本忠義，小坂聡太郎　他
- Total Pages
  199
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-20K16028
[Journal Article] 大腸内視鏡検査で治療経過を追ったメトロニダゾール抵抗性アメーバ性大腸炎2024
- Author(s)
  小坂聡太郎、神山長慶、長谷川英男、水上一弘、鹿子嶋洋明、草場敬浩、西田陽登、小林隆志、村上和成
- Journal Title
  
  大分県医学会雑誌
  
  Volume: 31 Pages: 52-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07984
[Journal Article] Tapeworm Infection Diagnosed after Campylobacter jejuni-induced Enteritis2024
- Author(s)
 Ozaka Sotaro、Soma Ryusuke、Takahashi Haruhiko、Shimomori Yuta、Fukuda Masahide、Tsutsumi Koshiro、Hirashita Yuka、Fukuda Kensuke、Ogawa Ryo、Mizukami Kazuhiro、Kagoshima Yomei、Sachi Nozomi、Kamiyama Naganori、Hasegawa Hideo、Kobayashi Takashi、Kodama Masaaki、Murakami Kazunari
- Journal Title
 
 Intern. Med.
 
 Volume: 63 Issue: 21 Pages: 2939-2942
- DOI
 10.2169/internalmedicine.3388-23
- ISSN
 0918-2918, 1349-7235
- Year and Date
 2024-11-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-23K16304, KAKENHI-PROJECT-21K07984
[Journal Article] CCL20/CCR6 chemokine signaling is not essential for pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis2023
- Author(s)
  Sachi Nozomi、Kamiyama Naganori、Saechue Benjawan、Ozaka Sotaro、Dewayani Astri、Ariki Shimpei、Chalalai Thanyakorn、Soga Yasuhiro、Fukuda Chiaki、Kagoshima Yomei、Ekronarongchai Supanuch、Kobayashi Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 641 Pages: 123-131
- DOI
  10.1016/j.bbrc.2022.11.088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-22K20860, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K16499, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-17H04649, KAKENHI-PROJECT-23K16304
[Journal Article] Tocilizumab-induced mucosal injury in the terminal ileum mimicking intestinal Behcet’s disease: A case report2023
- Author(s)
  Ozaka Sotaro、Fukuda Masahide、Takahashi Haruhiko、Tsutsumi Koshiro、Iwao Masao、Hirashita Yuka、Fukuda Kensuke、Okamoto Kazuhisa、Arakawa Mie、Ogawa Ryo、Endo Mizuki、Mizukami Kazuhiro、Kamiyama Naganori、Kobayashi Takashi、Kodama Masaaki、Murakami Kazunari
- Journal Title
  
  Medicine
  
  Volume: 102 Issue: 25 Pages: e34118-e34118
- DOI
  10.1097/md.0000000000034118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16024, KAKENHI-PROJECT-23K16304
[Journal Article] TRAF6 signaling in dendritic cells plays protective role against infectious colitis by limiting C. rodentium infection through the induction of Th1 and Th17 responses2023
- Author(s)
  Chalalai Thanyakorn、Kamiyama Naganori、Saechue Benjawan、Sachi Nozomi、Ozaka Sotaro、Ariki Shimpei、Dewayani Astri、Soga Yasuhiro、Kagoshima Yomei、Ekronarongchai Supanuch、Okumura Ryu、Kayama Hisako、Takeda Kiyoshi、Kobayashi Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 669 Pages: 103-112
- DOI
  10.1016/j.bbrc.2023.05.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15077, KAKENHI-PROJECT-23K16304, KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-22K20860
[Journal Article] GM-CSF-producing CCR2+ CCR6+ Th17 cells are pathogenic in dextran sodium sulfate-induced colitis model in mice2023
- Author(s)
  Ariki Shimpei、Ozaka Sotaro、Sachi Nozomi、Chalalai Thanyakorn、Soga Yasuhiro、Fukuda Chiaki、Kagoshima Yomei、Ekronarongchai Supanuch、Mizukami Kazuhiro、Kamiyama Naganori、Murakami Kazunari、Kobayashi Takashi
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 4 Pages: 267-276
- DOI
  10.1111/gtc.13008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-22K20860, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K16499, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-17H04649, KAKENHI-PROJECT-23K16304
[Journal Article] TRAF6 signaling in T cells is crucial for the pathogenicity of experimental autoimmune encephalomyelitis2023
- Author(s)
  Kamiyama Naganori、Saechue Benjawan、Sachi Nozomi、Dewayani Astri、Chalalai Thanyakorn、Ozaka Sotaro、Ariki Shimpei、Soga Yasuhiro、Kagoshima Yomei、Ekronarongchai Supanuch、Hidano Shinya、Kobayashi Takashi
- Journal Title
  
  International Immunology
  
  Volume: 36 Issue: 5 Pages: 241-256
- DOI
  10.1093/intimm/dxad055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K15077, KAKENHI-PROJECT-23K16304, KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-22K20860
[Journal Article] Acute Cholecystitis Associated with Eosinophilic Granulomatosis with Polyangiitis That Responded to Glucocorticoid Therapy2023
- Author(s)
  Ozaka Sotaro、Kodera Takamoto、Tsutsumi Koshiro、Fukuda Masahide、Iwao Masao、Hirashita Yuka、Takahashi Haruhiko、Fukuda Kensuke、Okamoto Kazuhisa、Arakawa Mie、Ogawa Ryo、Endo Mizuki、Mizukami Kazuhiro、Okimoto Tadayoshi、Kamiyama Naganori、Kodama Masaaki、Kobayashi Takashi、Murakami Kazunari
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 10 Pages: 1501-1506
- DOI
  10.2169/internalmedicine.0437-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-05-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-17H04649
[Journal Article] Differences in clinical features and morphology between differentiated and undifferentiated gastric cancer after Helicobacter pylori eradication2023
- Author(s)
  Kodama M, Mizukami K, Hirashita Y, Okimoto T, Wada Y, Fukuda M, Ozaka S, Kudo Y, Ito K, Ogawa R, Okamoto K, Fukuda K, Murakami K
- Journal Title
  
  PLos One
  
  Volume: 18 Issue: 3 Pages: 0282341-0282341
- DOI
  10.1371/journal.pone.0282341
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-22K16024, KAKENHI-PROJECT-23K16304, KAKENHI-PROJECT-23K06443
[Journal Article] TRAF6 signaling pathway in T cells regulates anti-tumor immunity through the activation of tumor specific Th9 cells and CTLs2022
- Author(s)
  Dewayani Astri、Kamiyama Naganori、Sachi Nozomi、Ozaka Sotaro、Saechue Benjawan、Ariki Shimpei、Goto Mizuki、Chalalai Thanyakorn、Soga Yasuhiro、Fukuda Chiaki、Kagoshima Yomei、Maekawa Yoichi、Kobayashi Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 613 Pages: 26-33
- DOI
  10.1016/j.bbrc.2022.04.125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03478, KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-22K20860, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K16499, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-17H04649, KAKENHI-PROJECT-19K21582
[Journal Article] Potential association of eEF1A dimethylation at lysine 55 in the basal area of Helicobacter pylori-eradicated gastric mucosa with the risk of gastric cancer: a retrospective observational study2022
- Author(s)
  Hirashita Yuka、Fukuda Masahide、Kodama Masaaki、Tsukamoto Yoshiyuki、Okimoto Tadayoshi、Mizukami Kazuhiro、Kawahara Yoshinari、Wada Yasuhiro、Ozaka Sotaro、Togo Kazumi、Kinoshita Keisuke、Fuchino Takafumi、Fukuda Kensuke、Okamoto Kazuhisa、Ogawa Ryo、Matsunari Osamu、Honda Koichi、Murakami Kazunari
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 22 Issue: 1 Pages: 490-490
- DOI
  10.1186/s12876-022-02521-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16024, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-23K21375
[Journal Article] Acute pancreatitis soon after COVID-19 vaccination2022
- Author(s)
  Ozaka Sotaro、Kodera Takamoto、Ariki Shimpei、Kobayashi Takashi、Murakami Kazunari
- Journal Title
  
  Medicine
  
  Volume: 101 Issue: 2 Pages: e28471-e28471
- DOI
  10.1097/md.0000000000028471
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-17H04649
[Journal Article] Comprehensive lipidomics of lupus-prone mice using LC-MS/MS identifies the reduction of palmitoylethanolamide that suppresses TLR9-mediated inflammation.2022
- Author(s)
  Ozaki T, Kamiyama N, Saechue B, Soga Y, Gotoh R, Nakayama T, Fukuda C, Dewayani A, Chalalai T, Ariki S, Ozaka S, Sonoda A, Hirose H, Gendo Y, Noguchi K, Sachi N, Hidano S, Maeshima K, Gotoh K, Masaki T, Ishii K, Osada Y, Shibata H, Kobayashi T
- Journal Title
  
  Genes Cells.
  
  Volume: 27 Issue: 7 Pages: 493-504
- DOI
  10.1111/gtc.12944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11605, KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K16499, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-17H04649
[Journal Article] COVID-19 vaccination and liver disease2022
- Author(s)
  Ozaka Sotaro、Kobayashi Takashi、Mizukami Kazuhiro、Murakami Kazunari
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 28 Issue: 48 Pages: 6791-6810
- DOI
  10.3748/wjg.v28.i48.6791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-20K07394, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-17H04649
[Journal Article] Saireito, a Japanese herbal medicine, alleviates leaky gut associated with antibiotic-induced dysbiosis in mice2022
- Author(s)
  Ozaka S、Sonoda A、Ariki S、Minata M、Kamiyama N、Hidano S、Sachi N、Ito K、Kudo Y、Dewayani A、Chalalai T、Ozaki T、Soga Y、Fukuda C、Mizukami K、Ishizawa S、Nishiyama M、Fujitsuka N、Mogami S、Kubota K、Murakami K、Kobayashi T
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 6 Pages: e0269698-e0269698
- DOI
  10.1371/journal.pone.0269698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K16499, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-17H04649
[Journal Article] Endoscopic Removal of Multiple Ingested Cylindrical Batteries2022
- Author(s)
  Ozaka Sotaro、Inoue Kunimitsu、Tasaki Takako、Ono Hideki、Murakami Kazunari
- Journal Title
  
  Cureus
  
  Volume: -
- DOI
  10.7759/cureus.21789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16028
[Journal Article] Analysis of the Prevalence and Species of Anisakis nematode in Sekisaba, Scomber japonicus Caught in Coastal Waters off Saganoseki, Oita in Japan2021
- Author(s)
 Hidano Shinya、Mizukami Kazuhiro、Yahiro Takaaki、Shirakami Kohei、Ito Hideyuki、Ozaka Sotaro、Ariki Shimpei、Saechue Benjawan、Dewayani Astri、Chalalai Thanyakorn、Soga Yasuhiro、Goto Mizuki、Sonoda Akira、Ozaki Takashi、Sachi Nozomi、Kamiyama Naganori、Nishizono Akira、Murakami Kazunari、Kobayashi Takashi
- Journal Title
 
 Jpn J Infect Dis
 
 Volume: 74 Issue: 5 Pages: 387-391
- DOI
 10.7883/yoken.JJID.2020.859
- NAID
 130008090913
- ISSN
 1344-6304, 1884-2836
- Year and Date
 2021-09-30
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K16499, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-18K08009, KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-17H04649
[Journal Article] Comment on “A case of acute necrotising pancreatitis following the second dose of Pfizer‐BioNTech COVID‐19 mRNA vaccine”2021
- Author(s)
  Ozaka Sotaro、Kobayashi Takashi、Murakami Kazunari
- Journal Title
  
  British Journal of Clinical Pharmacology
  
  Volume: 88 Issue: 5 Pages: 2449-2449
- DOI
  10.1111/bcp.15159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-17H04649
[Journal Article] Monomorphic epitheliotropic intestinal T-cell lymphoma presenting as melena with long-term survival: A case report and review of literature2021
- Author(s)
  Ozaka Sotaro、Inoue Kunimitsu、Okajima Tomoya、Tasaki Takako、Ariki Shimpei、Ono Hideki、Ando Takeaki、Daa Tsutomu、Murakami Kazunari
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 27 Issue: 38 Pages: 6501-6510
- DOI
  10.3748/wjg.v27.i38.6501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K17025
[Journal Article] Rectal varix treated with endoscopic cyanoacrylate injection therapy2021
- Author(s)
  Ozaka Sotaro、Gotoh Yasuhiko、Honda Shunichiro、Iwao Toshiaki、Kawahara Yoshinari、Kinoshita Keisuke、Nakaya Tomohisa、Noguchi Chishio、Kagawa Koichi、Murakami Kazunari
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: - Issue: 3 Pages: 791-795
- DOI
  10.1007/s12328-020-01305-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16028
[Journal Article] Protease inhibitory activity of secretory leukocyte protease inhibitor ameliorates murine experimental colitis by protecting the intestinal epithelial barrier2021
- Author(s)
  Ozaka S, Sonoda A, Ariki S, Kamiyama N, Hidano S, Sachi N, Ito K, Kudo Y, Minata M, Saechue B, Dewayani A, Chalalai T, Soga Y, Takahashi Y, Fukuda C, Mizukami K, Okumura R, Kayama H, Murakami K, Takeda K, Kobayashi T.
- Journal Title
  
  Genes to Cells
  
  Volume: 26 Issue: 10 Pages: 807-822
- DOI
  10.1111/gtc.12888
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07984, KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K16499, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-17H04649
[Journal Article] Development of a portable reverse transcription loop‐mediated isothermal amplification system to detect the E1 region of Chikungunya virus in a cost‐effective manner2020
- Author(s)
  Saechue Benjawan、Kamiyama Naganori、Fukuda Chiaki、Watanabe Kei、Soga Yasuhiro、Goto Mizuki、Dewayani Astri、Ariki Shimpei、Hirose Haruna、Ozaka Sotaro、Sachi Nozomi、Hidano Shinya、Shirin Tahmina、Mondal Dinesh、Murakami Kazunari、Kobayashi Takashi
- Journal Title
  
  Genes to Cells
  
  Volume: 9 Issue: 9 Pages: 615-625
- DOI
  10.1111/gtc.12797
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16028, KAKENHI-PROJECT-20K16499, KAKENHI-PROJECT-20K17025, KAKENHI-PROJECT-20K18482, KAKENHI-PROJECT-17H04649
[Presentation] CCL20/CCR6 axis is not necessarily required for experimental autoimmune encephalomyelitis2024
- Author(s)
  Nozomi Sachi, Naganori Kamiyama, Sotaro Ozaka, Chalalai Thanyakorn, Yasuhiro Soga, Yomei Kagoshima, Takashi Kobayashi.
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] 小児に対する下部消化管内視鏡検査の現状とその鎮静法に関する臨床的検討2024
- Author(s)
  小坂聡太郎, 堤康志郎, 髙橋晴彦, 福田健介, 小川竜, 水上一弘, 村上和成
- Organizer
  第20回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-23K16304
[Presentation] Investigating the Role of CCL20 on IMQ-Induced Psoriatic Inflammation Using CCL20 Deficient Mice.2023
- Author(s)
  Supanuch Ekronarongchai, Natsuki Ito, Nozomi Sachi, Yomei Kagoshima, Yasuhiro Soga, Thanyakorn Chalalai, Sotaro Ozaka, Naganori Kamiyama, Takashi Kobayashi.
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] In vitro and In vivo Analysis of the Effects of the Lipid Mediator Palmitoylethanolamide (PEA) on T Cells.2023
- Author(s)
  Yasuhiro Soga, Naganori Kamiyama, ThanyakornChalalai, Nozomi Sachi, Sotaro Ozaka, Yomei Kagoshima, Supanuch Ekronarongchai, Takashi Kobayashi.
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Development of new preventive methodfor congenital toxoplasmosis using CCR2-deficient mice.2023
- Author(s)
  Naganori Kamiyama, Mai Ueno, Nozomi Sachi, Ozaka Sotaro, Thanyakorn Chalalai, Yasuhiro Soga Yomei Kagoshima, Supanuch Ekronarongchai, Takashi Kobayashi
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] 抗菌ペプチド誘導を介した大建中湯のマウス腸内微生物叢に及ぼす影響と腸炎保護作用の解析2023
- Author(s)
  小坂聡太郎, 小林隆志, 村上和成
- Organizer
  第31回日本消化器関連学会週間 (JDDW 2023)
- Data Source
  KAKENHI-PROJECT-23K16304
[Presentation] 抗菌薬で生じるリーキーガットに対する柴苓湯の保護効果に関する基礎研究2023
- Author(s)
  小坂聡太郎, 神山長慶, 佐知望美, 堤康志郎, 髙橋晴彦, 福田健介, 小川竜, 水上一弘, 小林隆志, 村上和成
- Organizer
  第19回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-23K16304
[Presentation] The role of secretory leukocyte protease inhibitor in the pathogenesis of innammatory bowel disease and a colon protective effect of Daikenchuto.2023
- Author(s)
  Sotaro Ozaka, Naganori Kamiyama, Yomei Kagoshima, Nozomi Sachi, Thanyakom Chalalai, Supanuch Ekronarongchai, Yasuhiro Soga, Kazuhiro Mizukami, Kazunari Murakami, Takashi Kobayashi.
- Organizer
  United European Gastroenterology Week 2023
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] 炎症性腸疾患患者における5-ASA不耐に関する検討2023
- Author(s)
  小坂聡太郎, 髙橋晴彦, 水上一弘, 村上和成
- Organizer
  第115回日本消化器内視鏡学会九州支部例会
- Data Source
  KAKENHI-PROJECT-23K16304
[Presentation] 抗菌薬で生じるリーキーガットに対する柴苓湯の保護効果に関する基礎研究2023
- Author(s)
  小坂聡太郎, 神山長慶, 佐知望美, 堤康志郎, 髙橋晴彦, 福田健介, 小川竜, 水上一弘, 小林隆志, 村上和成
- Organizer
  第19回日本消化管学会総会学術総会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] 先天性トキソプラズマ症モデルマウスを用いたその予防法の開発2023
- Author(s)
  神山　長慶, 佐知　望美, 小坂　聡太郎, Thanyakorn Chalalai, 曽我　泰裕, 鹿子嶋　洋明, Supanuch Ekronarongchai, 小林　隆志
- Organizer
  第13回癌・炎症と抗酸化研究会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Analysis of pathophysiological functions of the chemokine CCL9 in multiple sclerosis using genome-edited mice.2023
- Author(s)
  Nozomi Sachi, Yomei Kagoshima, Supanuch Ekronarongchai, Yasuhiro Soga, Sotaro Ozaka, Naganori Kamiyama, Takashi Kobayashi.
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] 柴苓湯のマウス腸内細菌叢に及ぼす影響とLeaky gut改善作用の解析2023
- Author(s)
  鹿子嶋　洋明, 小坂　聡太郎, 神山　長慶, 佐知　望美, 曽我　泰裕, Supanuch Ekronarongchai, 水上　一弘, 村上　和成, 小林　隆志
- Organizer
  第13回癌・炎症と抗酸化研究会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] THE ROLE OF SECRETORY LEUKOCYTE PROTEASE INHIBITOR IN THE PATHOGENESIS OF INFLAMMATORY BOWEL DISEASE AND A COLON PROTECTIVE EFFECT OF DAIKENCHUTO2023
- Author(s)
  Sotaro Ozaka, Naganori Kamiyama, Yomei Kagoshima, Nozomi Sachi, Thanyakorn Chalalai, Supanuch Ekronarongchai, Yasuhiro Soga, Kazuhiro Mizukami, Kazunari Murakami, Takashi Kobayashi
- Organizer
  UEGW 2023 第31回欧州消化器病週間
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K16304
[Presentation] CCL20/CCR6ケモカインシグナル伝達は多発性硬化症の病態形成に必ずしも必要ではない2023
- Author(s)
  佐知　望美, 神山　長慶, 小坂　聡太郎, Thanyakorn Chalalai, 曽我　泰裕, 鹿子嶋　洋明, Supanuch Ekronarongchai, 小林　隆志
- Organizer
  第13回癌・炎症と抗酸化研究会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] 大建中湯はmicrobiomeを変化させ実験的大腸炎を軽減する2023
- Author(s)
  小坂聡太郎, 小林隆志, 村上和成
- Organizer
  第9回Gut Microbiota研究会
- Data Source
  KAKENHI-PROJECT-23K16304
[Presentation] Zika virus induces pathogenic T cell-attracting chemokines in the central nervous system and exacerbates experimental autoimmune encephalomyelitis2022
- Author(s)
  Naganori Kamiyama, Thanyakorn Chalalai, Sotaro Ozaka, Shimpei Ariki, Yomei Kagoshima, Nozomi Sachi, Takashi Kobayashi
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Physiological relevance of TRAF6 signaling in dendritic cells in controlling C. rodentium infection2022
- Author(s)
  Thanyakorn Chalalai, Naganori Kamiyama, Shimpei Ariki, Sotaro Ozaka, Nozomi Sachi, Yomei Kagoshima, Ryu Okumura, Kiyoshi Takeda, Takashi Kobayashi
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] 分泌型好中球プロテアーゼインヒビターは腸管上皮バリアを保護することでマウス実験腸炎を軽減する2022
- Author(s)
  小坂聡太郎, 有木晋平, 神山長慶, 鹿子嶋洋明, 佐知望美, Astri Dewayani, Thanyakorn Chalalai, 水上一弘, 竹田潔, 村上和成, 小林隆志
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] Physiological function of chemokine CCL20 and its receptor CCR6 in multiple sclerosis in mice2022
- Author(s)
  Nozomi Sachi, Naganori Kamiyama, Sotaro Ozaka, Shimpei Ariki, Thanyakorn Chalalai, Yomei Kagoshima, Takashi Kobayashi
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Identification of pathogenic Th17 cells in gastrointestinal tract using chemokine receptor deficient mice2022
- Author(s)
  Shimpei Ariki, Sotaro Ozaka, Nozomi Sachi, Yomei Kagoshima, Thanyakorn Chalalai, Naganori Kamiyama, Takashi Kobayashi
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Secretory leukocyte protease inhibitor ameliorates murine experimental colitis by protecting the intestinal epithelial barrier2022
- Author(s)
  Sotaro Ozaka, Shimpei Ariki, Yomei Kagoshima, Naganori Kamiyama, Nozomi Sachi, Thanyakorn Chalalai, Astri Dewayani, Takashi Kobayashi
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Functional analysis of chemokine receptor CCR2 in a murine congenital toxoplasmosis model2022
- Author(s)
  Noganori Kamiyama, Nozomi Sachi, Sotaro Ozaka, Shimpei Ariki, Thanyakorn Chalalai, Yasuhiro Soga, Chiaki Fukuda, Yomei Kagoshima, Supanuch Ekronarongchai, Masahiro Yamamoto, Takashi Kobayashi
- Organizer
  第15回寄生虫感染免疫研究会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Dysbiosisに起因するLeaky gutモデルに対する柴苓湯の有効性2022
- Author(s)
  小坂聡太郎, 有木晋平, 水上一弘, 神山長慶, 福田健介, 岡本和久, 小川竜, 沖本忠義, 小林隆志, 村上和成
- Organizer
  第30回日本消化器関連学会週間 (JDDW 2022)
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] Secretory leukocyte protease inhibitor ameliorates experimental colitis by protecting the intestinal epithelial barrier2022
- Author(s)
  Sotaro Ozaka, Shimpei Ariki, Naganori Kamiyama, Yomei Kagoshima, Nozomi Sachi, Thanyakorn Chalalai, Yasuhiro Soga, Kazuhiro Mizukami, Kazunari Murakami, Takashi Kobayashi
- Organizer
  第12回　癌・炎症と抗酸化研究会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] "Identification of a responsible amino acid in prME protein for cell entry of Zika virus using single-round infectious particles (SRIPs)"2021
- Author(s)
  Chiaki Fukuda, Naganori Kamiyama, Benjawan Saechue, Astri Dewayani, Chalalai Thanyakorn, Sotaro Ozaka, Shinpei Ariki, Yasuhiro Soga, Mizuki Minata, Nozomi Sachi, Shinya Hidano, Ryosuke Suzuki,Takashi Kobayashi
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Establishment of a reporter assay system to quantity TRAF6 mediated inflammatory signals and search for novel anti-inflammatory.2021
- Author(s)
  Soga Y., Kamiyama N., Saechue B., Dewayani A., Hidano S., Sachi N., Ozaka S., Ariki S., Goto M., Kobayashi T.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] Verification of T cell inhibitory effect of lipid mediator Oleylethanolamide2021
- Author(s)
  Yasuhiro Soga, Naganori Kamiyama, Takashi Ozaki, Benjawan Saechue, Astri Dewayani, Nozomi Sachi, Sotaro Ozaka, Shinpei Ariki, Thanyakorn Chalalai, Chiaki Fukuda, Takashi Kobayash
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Zika virus induces Th17 cell-attracting chemokines in the central nervous system and exacerbates neurological disorders.2021
- Author(s)
  Naganori Kamiyama, Benjawan Saechue, Astri Dewayani, Chalalai Thanyakorn, Sotaro Ozaka, Shimpei Ariki, Chiaki Fukuda, Yasuhiro Soga, Mizuki Minata, Nozomi Sachi, Shinya Hidano, Takashi Kobayashi.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] CCL20欠損マウスを用いた多発性硬化症の発症におけるCCL20の機能解析.2021
- Author(s)
  佐知望美，神山長慶，Benjawan Saechue，小坂聡太郎，Astri Dewayani，有木晋平，Thanyakorn Chalalai，曽我泰裕，福田千瑛，小林隆志.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] "CCL20欠損マウスを用いた多発性硬化症の発症におけるCCL20の機能解析 Analysis of the role of CCL20 in the development of multiple sclerosis using CCL20-deficient mice"2021
- Author(s)
  Nozomi Sachi, Naganori Kamiyama, Benjawan Saechue, Sotaro Ozaka, Astri Dewayani, Shimpei Ariki, Thanyakorn Chalalai, Yasuhiro Soga, Chiaki Fukuda, Takashi Kobayashi
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] 一回感染性ジカウイルス様粒子（SRIPｓ）を用いた宿主細胞侵入に関わるprME領域のアミノ酸の同定.2021
- Author(s)
  福田千瑛，神山長慶，Benjawan Saechue，Astri Dewayani，Thanyakorn Chalalai，小坂聡太郎，有木晋平，曽我泰裕，皆田美月，佐知望美，飛彈野真也，鈴木亮介，小林隆志.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] 大建中湯のSLPI発現増強を介した腸管保護作用の解析.2021
- Author(s)
  皆田美月, 小坂聡太郎, 有木晋平, 神山長慶, 佐知望美, Benjawan Saechue, Astri Dewayani, Thanyakorn Chalalai, 曽我泰裕, 福田千瑛, 水上一弘, 村上和成, 小林隆志.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] マウス腸炎モデルを用いた大建中湯のSLPI発現を介した腸管保護作用の解析2021
- Author(s)
  小坂聡太郎, 皆田美月, 有木晋平, 水上一弘, 神山長慶, 小林隆志, 村上和成.
- Organizer
  第29回日本消化器関連学会週間 (JDDW 2021)
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] 上部消化管出血を契機に診断され長期生存している単形性上皮向性腸管T細胞リンパ腫の1例2021
- Author(s)
  小坂聡太郎, 井上邦光, 岡嶋智也, 田崎貴子, 有木晋平, 小野英樹, 村上和成
- Organizer
  第111回日本消化器内視鏡学会九州支部例会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] T細胞特異的TRAF6欠損マウスを用いた腸管におけるnon-pathogenic Th17細胞に関する研究2021
- Author(s)
  有木晋平, 小坂聡太郎, 神山長慶, Benjawan Saechue, Astri Dewayani, Thanyakorn Chalalai, 佐知望美, 曽我泰裕, 福田千瑛, 水上一弘, 村上和成, 小林隆志
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] 柴苓湯はマウスにおいて抗菌薬によるdysbiosisに起因するLeaky gutを軽減する.2021
- Author(s)
  小坂聡太郎, 有木晋平, 皆田美月, 神山長慶，佐知望美，Benjawan Saechue，Astri Dewayani, Thanyakorn Chalalai,　曽我泰裕, 福田千瑛, 水上一弘, 村上和成, 小林隆志.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] TRAF6 regulates Th9 cells and cytotoxic T lymphocytes in tumor immunity2021
- Author(s)
  Astri Dewayani, Naganori Kamiyama, Shinya Hidano, Nozomi Sachi, Sotaro Ozaka, Shimpei Ariki, Benjawan Saechue, Yasuhiro Soga, Thanyakorn Chalalai, Chiaki Fukuda, Takashi Kobayashi
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] Physiological relevance of TRAF6 signaling in dendritic cells in controlling C. rodentium infection2021
- Author(s)
  Chalalai T., Kamiyama N., Saechue B., Dewayani A., Ariki S., Ozaka S., Sachi N., Fukuda C., Soga Y., Okumura R., Kayama H., Takeda K., Kobayashi T
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] TRAF6 promotes the migration of Th17 cells into the CNS by regulating CCR6 expression in experimental autoimmune encephalomyelitis mice.2021
- Author(s)
  Kamiyama N., Saechue B., Dewayani A., Thanyakorn C., Ozaka S., Ariki S., Soga Y., Goto M., Sachi N., Hidano S., Kobayashi T.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] 大建中湯のSLPI発現増強を介した腸管保護作用の解析2021
- Author(s)
  皆田美月, 小坂聡太郎, 有木晋平, 神山長慶, 佐知望美, Benjawan Saechue, Astri Dewayani, Thanyakorn Chalalai, 曽我泰裕, 福田千瑛, 水上一弘, 村上和成, 小林隆志
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] TRAF6 Regulates Th9 Cells and Cytotoxic T Lymphocytes in Tumor Immunity.2021
- Author(s)
  Dewayani A., Kamiyama N., Hidano S., Sachi N., Ozaka S., Ariki S., Saechue B., Soga Y., Chalalai T., Fukuda C., Kobayashi T.
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] 柴苓湯はマウスにおいて抗菌薬によるdysbiosisに起因するLeaky gutを軽減する2021
- Author(s)
  小坂聡太郎, 有木晋平, 皆田美月, 神山長慶，佐知望美，Benjawan Saechue，Astri Dewayani, Thanyakorn Chalalai,　曽我泰裕, 福田千瑛, 水上一弘, 村上和成, 小林隆志
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] 樹状細胞におけるTRAF6シグナルがCitrobacter rodentium感染性腸炎に与える役割.2021
- Author(s)
  望月晶子, Thanyakorn chalalai1, 伊藤加奈子, 有木晋平, 小坂聡太郎, 佐知望美, 神山長慶, 小林隆志.
- Organizer
  第11回癌・炎症と抗酸化研究会(CIA研究会).
- Data Source
  KAKENHI-PROJECT-21K07984
[Presentation] DSS腸炎モデルを用いたSLPIの結腸における生理的機能の解析2020
- Author(s)
  小坂聡太郎, 有木晋平, 園田光, 神山長慶, 飛彈野真也, 水上一弘, 小林隆志, 村上和成
- Organizer
  第28回 JDDW 日本消化器関連学会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] 抗生物質起因性大腸炎マウスモデルに対する柴苓湯の有効性の解明2020
- Author(s)
  小坂聡太郎, 園田光, 有木晋平, 水上一弘, 村上和成
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K16028
[Presentation] 内視鏡的シアノアクリレート注入療法が奏功した直腸静脈瘤の1例2020
- Author(s)
  小坂聡太郎, 本田俊一郎, 川原義成, 仲谷朋久, 野口地塩, 後藤康彦, 香川浩一, 村上和成
- Organizer
  第110回日本消化器内視鏡学会九州支部例会
- Data Source
  KAKENHI-PROJECT-20K16028

1. Kobayashi Takashi (30380520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 33 results
2. 村上和成 (00239485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
3. 前川洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 平下有香

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 有木晋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 正木孝幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 後藤孔郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 柴田洋孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ozaka Sotaro 小坂 聡太郎

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炎症性腸疾患におけるSLPIの新規バイオマーカーとしての可能性と有用性の検討Principal Investigator

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Elucidation of the pathophysiology of colitis in CCR-deficient mice and establishment of a functional classification method for intestinal Th17 cells.

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The functional analysis of antimicrobial peptide SLPI in the intestine and a colon protective effect of DaikenchutoPrincipal Investigator

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[Book] 国民の栄養白書 2021年度版 日本の食と栄養が創る 新時代の健康 第1部 日本人と食のチカラ 第2章 日本人の身体に合った食事～腸内環境から考える日本人の理想の食～2022

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[Book] 国民の栄養白書2021年度版2021

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[Book] 消化性潰瘍診療ガイドライン2020改訂第3版2020

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[Journal Article] 大腸内視鏡検査で治療経過を追ったメトロニダゾール抵抗性アメーバ性大腸炎2024

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[Journal Article] Tapeworm Infection Diagnosed after <i>Campylobacter jejuni</i>-induced Enteritis2024

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[Journal Article] CCL20/CCR6 chemokine signaling is not essential for pathogenesis in an experimental autoimmune encephalomyelitis mouse model of multiple sclerosis2023

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[Journal Article] Tocilizumab-induced mucosal injury in the terminal ileum mimicking intestinal Behcet’s disease: A case report2023

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[Journal Article] TRAF6 signaling in dendritic cells plays protective role against infectious colitis by limiting C. rodentium infection through the induction of Th1 and Th17 responses2023

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[Journal Article] GM-CSF-producing CCR2+ CCR6+ Th17 cells are pathogenic in dextran sodium sulfate-induced colitis model in mice2023

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[Journal Article] TRAF6 signaling in T cells is crucial for the pathogenicity of experimental autoimmune encephalomyelitis2023

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[Journal Article] Acute Cholecystitis Associated with Eosinophilic Granulomatosis with Polyangiitis That Responded to Glucocorticoid Therapy2023

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Ozaka Sotaro 小坂聡太郎

[Book] 国民の栄養白書　2021年度版　日本の食と栄養が創る　新時代の健康第1部日本人と食のチカラ第2章日本人の身体に合った食事～腸内環境から考える日本人の理想の食～2022