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NAGASAWA Shigeharu
長沢 滋治
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Alternative Names
長澤 滋治 ナガサワ シゲハル
NAGASAWA SHIGEHARU 長沢 滋治
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Researcher Number
70029958
External Links
Affiliation (based on the past Project Information)
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1998 – 2000: 北海道大学, 大学院・薬学研究科, 教授
1999: 北海道大学, 薬学部・衛生化学講座, 教授
1998: 北海道大学, 大学院・薬学系研究科, 教授
1998: 北海道大学, 大学院薬学研究科, 教授
1991 – 1997: 北海道大学, 薬学部, 教授
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1993: Hokkaido Univ. Fac.Pharm.Sci.Professor
1990: 北海道大学, 薬学部, 助教授
1989: 北海道大学, 医学部, 助教授
1988: 北海道大学, 薬学部
1986 – 1988: Faculty of Pharmaceutical Sciences, Hokkaido Univ., Associate Prof., 薬学部, 助教授
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Review Section/Research Field
Principal Investigator
Biological pharmacy
/
物質生物化学
/
応用薬理学・医療系薬学
Except Principal Investigator
Laboratory animal science
/
Virology
/
物質生物化学
Keywords
Principal Investigator
補体 / 免疫 / 補体系 / 生体防御 / Complement / 食細胞 / アポトーシス / 外因系凝固 / 急性相蛋白質 / 血漿蛋白質
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/ Immunology / 補体レセプター / COMPLEMENT / APOPTOSIS / 麻疹ウイルス / M.fermentans / tumor cells / complement / EF-1α / プロテアーゼ / Protease / C4b結合性蛋白質 / プロティンS / カリクレイン / 遺伝子解析 / セレン / 細胞増殖 / チオレドキシン還元酵素 / C4b結合蛋白質(C4bp) / プロテインS / インターロイキン-6(IL-6) / アナフィラトキシン / 血管内皮細胞 / レセプター / Anaphylatoxin / Host defense / Endothelial cells / Receptor / Fcレセプター / 免疫応答 / 抗体レセプター / 活性酸素 / PHAGOCYTES / IMMUNE RESPONSE / POSONIZATION / RECEPTORS / 制御因子 / 異種臓器移植 / 活性部位 / 遺伝子工学 / 臓器移植 / 補体制御因子 / Regulatory factor / Zeno-transplantation / Measles virus / Active site / Gene technology / オプソニン / マクロファージ / アポトシス / ガン細胞 / PHAGOCYTOSIS / OPSONIN / IMMUNOLOGY / MACROPHAGE / 先天性免疫 / ナチュラルキラー細胞(NK) / 癌細胞 / 細胞傷害作用 / NK細胞 / MHCクラスI / M161抗原 / オプソニン効果 / Innate immunity / natural killer cells (NK) / cytotoxicity / M. fermentans / スルファチド / MCP / セレブロシド / スフィンゴ脂質 / sulfatides / neutrophils / phagocytosis / apoptosis / C3コンベルターゼ / 活性化機構 / Complement system / Host defense system / C3 convertase / インターαトリプシンインヒビター / 阻害因子 / トリプシン / プロテアーゼ阻害物質 / Inter- trypsin Inhibitor / Plasma Protein / 人工膜 / 医用高分子膜 / 血漿分離膜 / Artificial Organ / Medical Polymer
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More
Except Principal Investigator
IX因子 / 組織因子 / β_2ー糖タンパク質 / C4b結合タンパク質 / フィブリノ-ゲン異常分子 / VII因子 / プロテインCインヒビタ- / VIII因子 / ヒトCD46(membrane cofactor protein) / トランススジェニックマウス / 麻疹ウイルス / 補体制御因子 / 異種移植 / 3′-UTサイレンサー / 麻疹ウィルスレセプター / CD46 / マーモセット / B Cell / cDNAクローニング / 単クローン抗体 / 合胞体形成阻害 / ウェスタンブロッティング / キニン / カリクレイン / キニノーゲン / チオールプロテアーゼ / プロテアーゼインヒビター / ラットTキニノーゲン / トリキニン / XII因子 / モノクロナール抗体 / キニンリセプター / ラットΤ-キニノーゲン / Kinin / Plasma kallikrein / Kininogen / Thiol-protease / Protease inhibitor / Rat T-kininogen / Ornitho-kinin
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Research Projects
(
17
results)
Co-Researchers
(
19
People)
Project Start Year (Newest)
Project Start Year (Oldest)
ヒトCD46高発現トランスジェニック動物の開発
Principal Investigator
SEYA Tsukasa
Project Period (FY)
1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Laboratory animal science
Research Institution
Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
第2の麻疹ウィルスレセプター -蛋白化学的同定とcDNAクローニング-
Principal Investigator
瀬谷 司
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Virology
Research Institution
Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
Studies on effector molecules of innate immunity responsible for cytotoxicity to tumor cells.
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
新規,細胞増殖因子としてのセレン含有蛋白質の探索
Principal Investigator
Principal Investigator
長澤 滋治
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Biological pharmacy
Research Institution
Hokkaido University
Studies on effector molecules of innate immunity responsible for cytotoxicity to tumor cells.
Principal Investigator
Principal Investigator
NAGASAWASHIGEHARU
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
APOPTOSIS AND COMPLEMENT-STUDIES ON THE MECHANISM OF COMPKEMENT ACTIVATION AND THE BIOLOGICAL SIGNIFICANCE
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
STUDIES ON THE BIOLOGICAL FUNCTIONS OF THE COMPLEMENT SYSTEM
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
Molecular design of low molecular fragments of complement regulatory factor for medical applications to zeno-transplantation and prevention of measles virus infection
Principal Investigator
Principal Investigator
NAGASAWA Shegeharu
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
Studies on molecular constitution and effector functions of complement system
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
Hokkaido University
ヒト血漿カリクレインの新しい基質蛋白質PKー120の構造解析に関する研究
Principal Investigator
Principal Investigator
長澤 滋治
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
物質生物化学
Research Institution
Hokkaido University
血液凝固の分子機構の研究
Principal Investigator
IWANAGA Sadaaki
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyushu University
補体系による外因系血液凝固の活性化と制御に関する研究
Principal Investigator
Principal Investigator
長沢 滋治
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
補体系による外因系血液凝固の活性化と制御に関する研究
Principal Investigator
Principal Investigator
長沢 滋治
Project Period (FY)
1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
Biochemical Studies on Human Inter- trypsin Inhibitor
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
物質生物化学
Research Institution
Hokkaido University
Artificial Organ and Complement----Basic Studies for Development of New Biomedical Polymer
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
応用薬理学・医療系薬学
Research Institution
Hokkaido University
Biological Significance of Plasma Kallikrein-kinin System
Principal Investigator
IWANAGA Sadaaki
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
物質生物化学
Research Institution
Kyushu University
Studies on the mechanism of activation of a protease in the complement system, C3 convertase.
Principal Investigator
Principal Investigator
NAGASAWA SHIGEHARU
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
物質生物化学
Research Institution
Hokkaido University
# of Projects (Dsc)
# of Projects (Asc)
1.
TAKAHASHI Kazuhiko
(10113581)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
2.
SEYA Tsukasa
(10301805)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
3.
YAMASHITA Toshiyuki
(90192400)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
NISHIMURA Hitoshi
(80241347)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
MURAKAMI Yusuke
(10250466)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
IWANAGA Sadaaki
(90029942)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
ARIGA Hiroyoshi
(20143505)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
MIYAGAWA Shuji
(90273648)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
SATO Noriyuki
(50158937)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
SAKAMOTO Wataru
(30001952)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
SASAKI Makoto
(10080003)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
NAKANISHI Shigetada
(20089105)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
KATORI Makoto
(50050365)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
MATSUDA Takehisa
(60142189)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
加藤 久雄
(80029959)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
森田 隆司
(90128108)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
小林 紀夫
(60008539)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
松田 道生
(50048980)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
松本 美佐子
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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