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NAGASAWA Shigeharu
長沢 滋治
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Alternative Names
長澤 滋治 ナガサワ シゲハル
NAGASAWA SHIGEHARU 長沢 滋治
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Researcher Number
70029958
External Links
Affiliation (based on the past Project Information)
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1998 – 2000: 北海道大学, 大学院・薬学研究科, 教授
1999: 北海道大学, 薬学部・衛生化学講座, 教授
1998: 北海道大学, 大学院・薬学系研究科, 教授
1998: 北海道大学, 大学院薬学研究科, 教授
1991 – 1997: 北海道大学, 薬学部, 教授
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1993: Hokkaido Univ. Fac.Pharm.Sci.Professor
1990: 北海道大学, 薬学部, 助教授
1989: 北海道大学, 医学部, 助教授
1988: 北海道大学, 薬学部
1986 – 1988: Faculty of Pharmaceutical Sciences, Hokkaido Univ., Associate Prof., 薬学部, 助教授
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Review Section/Research Field
Principal Investigator
Biological pharmacy
/
物質生物化学
/
応用薬理学・医療系薬学
Except Principal Investigator
Virology
/
Laboratory animal science
/
物質生物化学
Keywords
Principal Investigator
補体 / 免疫 / 補体系 / アポトーシス / Complement / 生体防御 / 食細胞 / COMPLEMENT / 血漿蛋白質 / 急性相蛋白質
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/ 外因系凝固 / プロテアーゼ / Immunology / complement / EF-1α / tumor cells / APOPTOSIS / M.fermentans / Protease / 麻疹ウイルス / 補体レセプター / phagocytosis / C4b結合蛋白質(C4bp) / 先天性免疫 / ガン細胞 / 阻害因子 / レセプター / プロティンS / 人工膜 / apoptosis / sulfatides / プロテアーゼ阻害物質 / インターαトリプシンインヒビター / Medical Polymer / 血漿分離膜 / IMMUNOLOGY / アナフィラトキシン / MHCクラスI / カリクレイン / セレブロシド / neutrophils / 細胞傷害作用 / Plasma Protein / Anaphylatoxin / RECEPTORS / C4b結合性蛋白質 / 制御因子 / 医用高分子膜 / NK細胞 / 細胞増殖 / M161抗原 / Inter- trypsin Inhibitor / 血管内皮細胞 / 活性酸素 / 異種臓器移植 / 臓器移植 / スルファチド / Active site / セレン / トリプシン / プロテインS / Host defense system / 遺伝子解析 / M. fermentans / IMMUNE RESPONSE / 活性化機構 / Fcレセプター / natural killer cells (NK) / スフィンゴ脂質 / マクロファージ / 補体制御因子 / POSONIZATION / C3 convertase / C3コンベルターゼ / オプソニン / Artificial Organ / PHAGOCYTES / Regulatory factor / MACROPHAGE / OPSONIN / Receptor / 活性部位 / Endothelial cells / 遺伝子工学 / 癌細胞 / インターロイキン-6(IL-6) / Zeno-transplantation / Gene technology / 免疫応答 / Measles virus / PHAGOCYTOSIS / Innate immunity / チオレドキシン還元酵素 / ナチュラルキラー細胞(NK) / Complement system / cytotoxicity / 抗体レセプター / オプソニン効果 / アポトシス / Host defense / MCP
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More
Except Principal Investigator
cDNAクローニング / 組織因子 / チオールプロテアーゼ / 合胞体形成阻害 / キニンリセプター / プロテインCインヒビタ- / XII因子 / 単クローン抗体 / プロテアーゼインヒビター / キニノーゲン / 麻疹ウイルス / IX因子 / 3′-UTサイレンサー / C4b結合タンパク質 / Thiol-protease / Protease inhibitor / ウェスタンブロッティング / β_2ー糖タンパク質 / Kinin / 補体制御因子 / Kininogen / B Cell / Plasma kallikrein / Ornitho-kinin / 異種移植 / CD46 / VIII因子 / ラットTキニノーゲン / フィブリノ-ゲン異常分子 / トリキニン / ヒトCD46(membrane cofactor protein) / VII因子 / Rat T-kininogen / モノクロナール抗体 / マーモセット / 麻疹ウィルスレセプター / ラットΤ-キニノーゲン / トランススジェニックマウス / カリクレイン / キニン
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Research Projects
(
17
results)
Co-Researchers
(
19
People)
Project Start Year (Newest)
Project Start Year (Oldest)
ヒトCD46高発現トランスジェニック動物の開発
Principal Investigator
SEYA Tsukasa
Project Period (FY)
1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Laboratory animal science
Research Institution
Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
第2の麻疹ウィルスレセプター -蛋白化学的同定とcDNAクローニング-
Principal Investigator
瀬谷 司
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Virology
Research Institution
Research Institute, Osaka Medical Center for Cancer and Cardiovascular Disaeses
Studies on effector molecules of innate immunity responsible for cytotoxicity to tumor cells.
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
新規,細胞増殖因子としてのセレン含有蛋白質の探索
Principal Investigator
Principal Investigator
長澤 滋治
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Biological pharmacy
Research Institution
Hokkaido University
Studies on effector molecules of innate immunity responsible for cytotoxicity to tumor cells.
Principal Investigator
Principal Investigator
NAGASAWASHIGEHARU
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
APOPTOSIS AND COMPLEMENT-STUDIES ON THE MECHANISM OF COMPKEMENT ACTIVATION AND THE BIOLOGICAL SIGNIFICANCE
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
STUDIES ON THE BIOLOGICAL FUNCTIONS OF THE COMPLEMENT SYSTEM
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1994 – 1995
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
Molecular design of low molecular fragments of complement regulatory factor for medical applications to zeno-transplantation and prevention of measles virus infection
Principal Investigator
Principal Investigator
NAGASAWA Shegeharu
Project Period (FY)
1994 – 1996
Research Category
Grant-in-Aid for Scientific Research (A)
Research Field
Biological pharmacy
Research Institution
HOKKAIDO UNIVERSITY
Studies on molecular constitution and effector functions of complement system
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Biological pharmacy
Research Institution
Hokkaido University
ヒト血漿カリクレインの新しい基質蛋白質PKー120の構造解析に関する研究
Principal Investigator
Principal Investigator
長澤 滋治
Project Period (FY)
1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
物質生物化学
Research Institution
Hokkaido University
血液凝固の分子機構の研究
Principal Investigator
IWANAGA Sadaaki
Project Period (FY)
1990
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Kyushu University
補体系による外因系血液凝固の活性化と制御に関する研究
Principal Investigator
Principal Investigator
長沢 滋治
Project Period (FY)
1989
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
補体系による外因系血液凝固の活性化と制御に関する研究
Principal Investigator
Principal Investigator
長沢 滋治
Project Period (FY)
1988
Research Category
Grant-in-Aid for Scientific Research on Priority Areas
Research Institution
Hokkaido University
Biochemical Studies on Human Inter- trypsin Inhibitor
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
物質生物化学
Research Institution
Hokkaido University
Artificial Organ and Complement----Basic Studies for Development of New Biomedical Polymer
Principal Investigator
Principal Investigator
NAGASAWA Shigeharu
Project Period (FY)
1987 – 1988
Research Category
Grant-in-Aid for Developmental Scientific Research
Research Field
応用薬理学・医療系薬学
Research Institution
Hokkaido University
Biological Significance of Plasma Kallikrein-kinin System
Principal Investigator
IWANAGA Sadaaki
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
物質生物化学
Research Institution
Kyushu University
Studies on the mechanism of activation of a protease in the complement system, C3 convertase.
Principal Investigator
Principal Investigator
NAGASAWA SHIGEHARU
Project Period (FY)
1985 – 1986
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
物質生物化学
Research Institution
Hokkaido University
# of Projects (Dsc)
# of Projects (Asc)
1.
TAKAHASHI Kazuhiko
(10113581)
# of Collaborated Projects:
9 results
# of Collaborated Products:
0 results
2.
SEYA Tsukasa
(10301805)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
3.
YAMASHITA Toshiyuki
(90192400)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
NISHIMURA Hitoshi
(80241347)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
MURAKAMI Yusuke
(10250466)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
IWANAGA Sadaaki
(90029942)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
ARIGA Hiroyoshi
(20143505)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
MIYAGAWA Shuji
(90273648)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
SATO Noriyuki
(50158937)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
SAKAMOTO Wataru
(30001952)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
SASAKI Makoto
(10080003)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
NAKANISHI Shigetada
(20089105)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
KATORI Makoto
(50050365)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
MATSUDA Takehisa
(60142189)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
加藤 久雄
(80029959)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
森田 隆司
(90128108)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
17.
小林 紀夫
(60008539)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
18.
松田 道生
(50048980)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
19.
松本 美佐子
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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