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FUJIWARA Yoshisada  藤原 美定

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… Alternative Names

藤原 義定  フジワラ ヨシサダ

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Researcher Number 70030848
Affiliation (based on the past Project Information) *help 1998 – 2000: 神戸大学, 医学部, 教授
1996: KOBE UNIVERSITY SCHOOL OF MEDICINE,PROFESSOR, 医学部・, 教授
1987 – 1996: 神戸大学, 医学部, 教授
1995: 神戸大学, 医学部, 助教授
1986: Kobe University School of Medicine , Professor, 医学部, 教授
1985: 神戸大学, 医, 教授
Review Section/Research Field
Principal Investigator
放射線5生物学 / 環境影響評価(含放射線生物学) / Biological Sciences
Except Principal Investigator
環境影響評価(含放射線生物学) / Experimental pathology / Biological Sciences / 放射線5生物学
Keywords
Principal Investigator
色素性乾皮症 / 修復遺伝子 / DNA修復 / VDAC / Bcl-XL / Bax / cDNA / ミトコンドリア / Bcl-2 / アポトーシス … More / 放射線 / DNA除去修復 / 発癌 / Mitomycin C / Cross-link repair gene / DNA-nediated gene transfer / Fanconi's anemia / 形質転換 / マイトマイシンC / ファンコニ貧血症 / Cytochrome c release / Mitochondria / Apoptosis / Ionizing radiation / カスパーゼ活性化DNase(CAD) / DNaseγ / Ca^<2+> / チトクロームC / ミトコンドリア膨化 / Bax蛋白質 / p53蛋白質 / 放射線アポトーシス / ウオルトマンニン / アタキシア細胞 / Li-Fraumeni細胞 / ATM / p53リン酸化 / p53 / チトクロームc遊離 / Expression cloning / XPD-complementing cDNA transformation / repair defect / DNA excision repair / xeroderma pigmentosum / D群相補遺伝子 / DNA除去終復 / cDNA導入による形質転換 / D群相補cDNA / 発現クローニング / DNA修復欠損 / 色素性乾皮症D群 / 修復因子 / (6-4)産物抗体 / チミンダイマー抗体 / 日本人色素性乾皮症患者の現况 / 皮膚発癌 / 塩基2量体と(6ー4)産物のモノクローナル抗体 / 不定期DNA合成 / 修復タンパク因子 / 除去修復 / A群遺伝子 / DNA導入 / UV抵抗性形質転換 / 細胞不死化 / C-myc / H-ras / 2細胞 / 【C_3】H10T1 / 染色体異常 / 発癌遺伝子 / X線形質転換 / ヒト線維芽細胞 / Bak / チトクロームC遊離 / チトクロームc / イオン化放射線 / 変異 / 抗XPD抗体 / DNAヘリカーゼ / D群色素性乾皮症(XPD)タンパク質 / D群色素性乾皮症(XPD)遺伝子 / 遺伝子変異 / 色素性乾皮症D群抗体 / 修復ヘリカーゼ / 色素性乾皮症D群蛋白質 / 色素性乾皮症D群遺伝子 / ミスマッチ修復酵素 / APEXヌクレアーゼ / 発癌性遺伝子突然変異 / 損傷認識抗体 / 紫外線DNA損傷 / 色素性乾皮症相補蛋白 / 色素性乾皮症遺伝子 / 発癌性突然変異 / UV損傷に対する特異抗体 / 修復酵素 / 色素性乾皮症A群の遺伝子診断 / in vitro修復検出系 / UV誘発突然変異 / UV損傷単クロ-ン抗体 / DNA依存性ATPase / A群色素性乾皮症相神遺伝子 / 突然変異 / DNA損傷特異抗体 / 修復タンパク / 高発癌性遺伝病 … More
Except Principal Investigator
p53 / DNA損傷 / 日光角化症 / 皮膚癌有病率 / 皮膚癌検診 / 発癌の危険因子 / 紫外線発癌 / 老化 / VDAC / Caspase / Bcl-2 / Bax / apoptosis / アポトーシス / 色素性乾皮症 / 皮膚癌罹患率 / 紫外線 / 神経 / 遺伝病 / アミロイド / 脳 / Cytochrome C / DNase γ / CAD / DNase / X線 / Cytocrome C / DNaseγ / Calcium ions / U937 / MOLT-4 / APOPTOSIS / RADIATION / 細胞内Ca^<2+>濃度 / カルパイン / DNAラダー / 核の形態変化 / ヒト白血病細胞 / Molt-4 / BAPTA-AM / カルシウムイオン / 放射線 / 環境因子 / 早老症 / 骨粗鬆症 / アルツハイアー病 / 生理的老化 / promoter element / Tumor suppression / UV / stress response / transcription / ras / トランスジェニックマウス / 老年痴呆 / 生形態形成 / DNA損傷と修復 / 太陽光 / 光生物学 / 遺伝子 / 痴呆 / アルツハイマ-病 / polymerase chain reaction / アミロイド前駆体タンパク / メッセンジャーRNA / cDNAライブラリー / アルツハイマー病 Less
  • Research Projects

    (26 results)
  • Co-Researchers

    (39 People)
  •  ヒトp53遺伝子の転写開始決定機構と新しい転写開始因子の機能解析

    • Principal Investigator
      野田 朝男
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  放射線アポトーシスにおけるチトクロームC遊離のチャネル機構Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  放射線アポートシスのミトコンドリア及びDNaseγによる制御Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kobe University
  •  Molecular analysis of the role of DNases in radiation-induced apoptosis.

    • Principal Investigator
      NODA Asao
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Kobe University
  •  Molecular pathways and mechanism of radiation-induced apoptosis.Principal Investigator

    • Principal Investigator
      FUJIWARA Yoshisada
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Kobe University
  •  D群色素性乾皮症(XPD)タンパクの機能Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  太陽紫外線誘発皮膚癌の臨床疫学的研究-本邦人における危険因子とその対策-

    • Principal Investigator
      市橋 正光
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  MOLECULAR MECHANISM OF RADIATION-INDUCED-APOPTOSIS

    • Principal Investigator
      KONDO Takashi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      KOBE UNIVERSITY
  •  色素性乾皮症D群の変異とタンパク機能Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  太陽紫外線誘発皮膚癌の臨床疫学的研究 -本邦人における危険因子とその対策-

    • Principal Investigator
      市橋 正光
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  色素性乾皮症の修復欠損に関する遺伝子とタンパクの異常Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  太陽紫外線誘発皮膚癌の臨床疫学的研究-本邦人における危険因子とその対策-

    • Principal Investigator
      市橋 正光
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  色素性乾皮症の修復欠損に関する遺伝子とタンパク質の異常Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  色素性乾皮症の修復欠損に関わる遺伝子とタンパクの異常Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  アルツハイマ-病に関連した遺伝子異常の解析

    • Principal Investigator
      榊 佳之
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Expression cloning of the gene for complementing xeroderma pigmentosum group D.Principal Investigator

    • Principal Investigator
      FUJIWARA Yoshisada
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      放射線5生物学
    • Research Institution
      Kobe University
  •  アルツハイマ-病に関連した遺伝子異常の解析

    • Principal Investigator
      榊 佳之
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  「第11回国際光生物学会議」開催準備のための統合研究

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      放射線5生物学
    • Research Institution
      Kyoto University
  •  高発癌性遺伝病の修復欠損要因と修復遺伝子の解析Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  アルツハイマー病に関連した遺伝子異常の解析

    • Principal Investigator
      宮武 正
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Niigata University
  •  高発癌性遺伝病の修復欠損要因と修復遺伝子の解析Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  高発癌性遺伝病の修復欠損要因と修復遺伝子の解析Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  老化研究のストラテジー

    • Principal Investigator
      朝長 正徳
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  高発癌性遺伝病色素性乾皮症A群に欠損する遺伝子と形質転換Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  細胞不死化とがん遺伝子導入による形質転換Principal Investigator

    • Principal Investigator
      藤原 美定
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  DNA-MEDIATED GENE TRANSFER TO FANCONI'S ANEMIA CELLS AND MOLECULAR CLONING OF THE HUMAN REPAIR GENE CONFERRING MITOMYCIN C RESISTANCEPrincipal Investigator

    • Principal Investigator
      FUJIWARA Yoshisada
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      放射線5生物学
    • Research Institution
      KOBE UNIVERSITY
  • 1.  二階堂 修 (60019669)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  八木 孝司 (80182301)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  MATSUMOTO Akira (80181759)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  NODA Asao (40294227)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  武部 啓 (10028318)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  市橋 正光 (00030867)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  佐藤 吉昭 (70013894)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  山泉 克 (70107093)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  田中 亀代次 (80144450)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  宮武 正 (50048998)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  竹田 俊男 (00027088)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  榊 佳之 (10112327)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  榎本 武美 (80107383)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  渡辺 昌 (60051637)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  佐藤 茂秋 (00076994)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  井上 勝平 (60040549)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  KONDO Takashi (40143937)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  小野寺 一清 (90012773)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  吉川 和明 (30094452)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  嶋 昭紘 (60011590)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  石崎 寛治 (70111987)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  関 周司 (50032884)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  田村 奈緒子 (50311783)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  内海 博司 (20025646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  今村 貞夫 (30026869)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  池永 溝生 (70025378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  三浦 直行 (40165965)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  三木 哲郎 (00174003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  大木 操 (00158792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  清水 信義 (50162706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  金田 安史 (10177537)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  三木 吉治 (30028336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  堀越 貴志 (40145587)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  新盛 英世 (50226354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  林部 一人 (40198875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  朝長 正徳 (10072977)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  後藤 佐多良 (10012650)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  松尾 光芳 (20072986)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  YAMAMOTO Yoko (50166831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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