ISOBE Yoshiaki 磯部芳明

Researcher Number	70094357
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2008 – 2010: Nagoya City University, 大学院・医学研究科, 助教 2002 – 2003: 名古屋市立大学, 大学院・医学研究科, 助手 1994 – 1999: 名古屋市立大学, 医学部, 助手 1989 – 1992: 名古屋市立大学, 医学部, 助手 1988: 名古屋市立大学, 医学部第二生理, 助手 1988: Department of Physiology, Nagoya City University Medical School, 医学部第二生理学, 助手
Review Section/Research Field	Principal Investigator Environmental physiology (including Physical medicine and Nutritional physiology) / 環境生理学(含体力医学･栄養生理学) / Environmental physiology (including Physical medicine and Nutritional physiology) Except Principal Investigator Neurophysiology and muscle physiology
Keywords	Principal Investigator Arg-vasopressin / 視交叉上核 / 概日リズム / mRNA / vasopressin / Suprachiasmatic nuclei / GABA / Vasopressin / Vasoactive intestinal peptide / Circadian rhythm … More / Bmal1 / Melatonin / Per / RT-PCR / AP-1 / c-fos / transcription / VIP / Gastrin releasing peptide / 時計遺伝子 / Pineal gland / suprachiasmatic nucleus / Clock controlled gene / 松果体 / Bmall / saprachiasmatic nucleus / Urcadidn vthythm / CRE(B) / 5'-RACE / messenger RNA / バソプレッシン / nRNA / 転写因子 / IEG / 転写 / Clock / プロモーター / clock / per / AP-1(AP-2) / Glutamate / 体温リズム / 自発行動リズム / glutamete / gdstrin / VAsoactive gntestinal peptide / slice culture / Arg-Vasopressin / glutamate / Culture / Development / Somatostatin / サ-カディアンリズム / 細胞培養 / サ-カジアンリズム / Intracell Ca / Circadian rhtyhm / Suprachiasmatic nucleus / Arginine Vasopressin / Intracellular Ca / Gastrin releacing peptide / Slice culture / Vasoactive Intestinal peptide / Supradriasmatsc nucleus / Argine Vasopressin / チェックポイント / 分化 / ES細胞 / 細胞周期 … More Except Principal Investigator 移植 / 可塑性 / Parkinson's disease / 栄養因子 / ラット / 表現型 / 尾状核 / ドーパミン細胞 / クロマフィン細胞 / レセプタ- / ド-パミン / パ-キンソン病 / Plasticity / Differentiation / Caudate / Chromaffin cell / Dopamine / Transplantation / Ca電流 / ドーパミング / 分化 / パーキンソン病 / substantia nigra / striatum / Phenotypic plasticity / trophic factor / dopamine / neuronal grafting / タンパク / mRNA / カテコラミン / 黒質 / 線条体 / 脳神経移植 / ノルアドレナリン細胞 Less

Relationship of circadian rhythm with cycle controlPrincipal Investigator
- Principal Investigator
  
  ISOBE Yoshiaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nagoya City University
Analysis of ontogeny of circadian rhythm and the transmission of circadian-rhythm-informationPrincipal Investigator
- Principal Investigator
  
  ISOBE Yoshiaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nagoya City University
Mechanisms of circadian rhythm analyzed from transcription factor of mRNA in suprachiasmatic nucleusPrincipal Investigator
- Principal Investigator
  
  ISOBE Yoshiaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nagoya City University
Mechanisms of circadian rhythm analyzed from transcription factor of mRNA in suprachiasmatic nucleusPrincipal Investigator
- Principal Investigator
  
  ISOBE Yoshiaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nagoya City University
Molecular mechanisms of development of circadian rhythm in relation to transcription factor of peptide synthesis.Principal Investigator
- Principal Investigator
  
  ISOBE Yoshiaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nagoya City University
Molecular basis of the circadian rhythm for peptides mRNAPrincipal Investigator
- Principal Investigator
  
  ISOBE Yoshiaki
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  環境生理学(含体力医学･栄養生理学)
- Research Institution
  Nagoya City University
移植カテコラミン細胞の可塑性とその制御環境因子
- Principal Investigator
  
  NISHINO Hitoo
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya City University
Phenotypic Plasticity of Grafted Catecholaminergic Neurons and its Regulatory Mechanisms.
- Principal Investigator
  
  NISHINO Hitoo
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Nagoya City University
クロマフィン細胞の尾状核移植による運動障害の修復とドーパミン神経細胞への分化機構
- Principal Investigator
  
  西野仁雄
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya City University
The mechanism of differentiation of transplanted chromaffin cells into dopaminergic neurons.
- Principal Investigator
  
  NISHINO Hitoo
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Nagoya City University Medical School
  Toyama Medical and Pharmaceutical University

All 2011 2010 2008

All Journal Article Presentation

[Journal Article] Circadian rhythm of enolase in suprachiasmatic nucleus depends on the mitochondrial function.2011
- Author(s)
  Isobe, Y., Hida, H., Nishino, H.
- Journal Title
  
  J.Neurosci.Res. 89
  
  Pages: 936-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Journal Article] Circadian rhythm of enolase in suprachiasmatic nucleus depends on the mitochondrial function.2011
- Author(s)
  Isobe, Y., Hida, H., Nishino, H.
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: 89 Pages: 936-944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Journal Article] Circadian rhythm of metabolic oscillation in suprachiasmatic nucleus depends on the mitochondrial oxidation state, reflected by cytochrome C oxidase and LDH.2011
- Author(s)
  Isobe, Y., Hida, H., Nishino, H.
- Journal Title
  
  J.Neurosci.Res. 89
  
  Pages: 929-935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Journal Article] Circadian rhythm of metabolic oscillation in suprachiasmatic nucleus depends on the mitochondrial oxidation state, reflected by cytochrome C oxidase and LDH2011
- Author(s)
  Isobe, Y., Hida, H., Nishino, H.
- Journal Title
  
  J.Neurosci.Res.
  
  Volume: 89 Pages: 929-935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Journal Article] Enhanced neurogenesis from neural progenitor cells with G1/S-phase cell cycle arrest is mediated by transforming growth factor betal.2008
- Author(s)
  Misuml S, Kim TS, Jung CG, Masuda T, Urakawa S, Isobe Y, Furuyama F, Nishino H, Hida H.
- Journal Title
  
  Eur J Neurosci. 28
  
  Pages: 1049-1059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Journal Article] Enhanced neurogenesis from neural progenitor cells with G1/S-phase cell cycle arrest is mediated by transforming growth factor betal.2008
- Author(s)
  Misumi, S., Kim, TS., Jung, CG., Masuda, T., Urakawa, S., Isobe, Y., Furuyama, F., Nishino, H., Hida, H.
- Journal Title
  
  Eur J Neurosci. 28
  
  Pages: 1049-1059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Journal Article] Increase in dopaminergic neurons from mouse embryonic stem cellderived neural progenitor/stem cells is mediated by hypoxia inducible factor-lalpha.2008
- Author(s)
  Kim TS, Misumi S, Jung CG, Masuda T, Isobe Y. Furuyama F, Nishino H, Hida H
- Journal Title
  
  J Neurosci Res 86
  
  Pages: 2353-2359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Journal Article] Increase in dopaminergic neurons from mouse embryonic stem cell-derived neural progenitor/stem cells is mediated by hypoxia inducible factor-1alpha.2008
- Author(s)
  Kim, TS., Misumi, S., Jung, CG., Masuda, T., Isobe, Y., Furuyama, F., Nishino, H., Hida, H.
- Journal Title
  
  J Neurosci Res. 86
  
  Pages: 2353-2362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Journal Article] Diethylnitrosamine-induced hepatic lesions are greater in rats maintained under a light-dark cycle than under constant light, related to the locomotor activity rhythm.2008
- Author(s)
  Isobe, Y., Fukamachi, K., Hida, H., Tsuda, H., Nishino, H.
- Journal Title
  
  Asian Pac.J.Cancer Prev. 9
  
  Pages: 619-624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590234
[Presentation] Diethylnitrosamineの明暗周期下投与時の肝毒性は24時間に2峰性をしめす2010
- Author(s)
  磯部芳明、津田洋幸
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20590234
[Presentation] ES細胞のサーカディアンリズムと細胞周期との関係2010
- Author(s)
  磯部芳明
- Organizer
  第33日本神経科学大会
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Data Source
  KAKENHI-PROJECT-20590234
[Presentation] ES細胞のサーカディアンリズムと細胞周期との関係2010
- Author(s)
  磯部芳明
- Organizer
  第33日本神経科学大会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20590234
[Presentation] Diethylnitrosamine induced hepatic carcinogenicity was cruel kept under the light-dark cycle than constant dim light and different by an injection-time of day in rats.2008
- Author(s)
  Isobe, Y., Tsuda Y.
- Organizer
  18th International Congress of Biometeorology (ICB2008)
- Place of Presentation
  Tokyo Tower Hall Funabori
- Data Source
  KAKENHI-PROJECT-20590234
[Presentation] Diethylnitrosamine induced hepatic carcinogenicity was cruel kept under the light-dark cycle than constant dim light and different by an injection-time of day in rats2008
- Author(s)
  Isobe Y, TsudaY.
- Organizer
  18th International Congress of Biometeorology (ICB2008)
- Place of Presentation
  東京船堀(タワホール船堀)
- Data Source
  KAKENHI-PROJECT-20590234
[Presentation] Diethylnitrosamineの明暗周期下での投与時刻による、自発活動リズムと肝ガン発生の差異(1P-G-116)2008
- Author(s)
  磯部芳明、津田洋幸
- Organizer
  第85 回日本生理学会大会
- Place of Presentation
  京王プラザホテル東京
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-20590234

1. NISHINO Hitoo (60073730)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. HASHITANI Takeshi (30172852)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. INOUYE Shinichi (10274151)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. FURUYAMA Fujiya (00080101)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. NAKANISHI Makoto (40217774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIDA Hideki (00305525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. FUJIMOTO Ichirou (70264710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NISHIJO Hisao (00189284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKAMURA Kiyomi (20143860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ONO Taketoshi (50019577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 佐藤春彦 (20080004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ISOBE Yoshiaki 磯部 芳明

Research Projects

Research Products

Co-Researchers

Relationship of circadian rhythm with cycle controlPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of ontogeny of circadian rhythm and the transmission of circadian-rhythm-informationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of circadian rhythm analyzed from transcription factor of mRNA in suprachiasmatic nucleusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of circadian rhythm analyzed from transcription factor of mRNA in suprachiasmatic nucleusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of development of circadian rhythm in relation to transcription factor of peptide synthesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis of the circadian rhythm for peptides mRNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

移植カテコラミン細胞の可塑性とその制御環境因子

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Phenotypic Plasticity of Grafted Catecholaminergic Neurons and its Regulatory Mechanisms.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クロマフィン細胞の尾状核移植による運動障害の修復とドーパミン神経細胞への分化機構

Principal Investigator

Project Period (FY)

Research Category

Research Institution

The mechanism of differentiation of transplanted chromaffin cells into dopaminergic neurons.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Circadian rhythm of enolase in suprachiasmatic nucleus depends on the mitochondrial function.2011

Author(s)

Journal Title

Data Source

[Journal Article] Circadian rhythm of enolase in suprachiasmatic nucleus depends on the mitochondrial function.2011

Author(s)

Journal Title

Data Source

[Journal Article] Circadian rhythm of metabolic oscillation in suprachiasmatic nucleus depends on the mitochondrial oxidation state, reflected by cytochrome C oxidase and LDH.2011

Author(s)

Journal Title

Data Source

[Journal Article] Circadian rhythm of metabolic oscillation in suprachiasmatic nucleus depends on the mitochondrial oxidation state, reflected by cytochrome C oxidase and LDH2011

Author(s)

Journal Title

Data Source

[Journal Article] Enhanced neurogenesis from neural progenitor cells with G1/S-phase cell cycle arrest is mediated by transforming growth factor betal.2008

Author(s)

ISOBE Yoshiaki 磯部芳明