TSUTSUI Ken 筒井研

Researcher Number	70108158
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2013: 岡山大学, 医歯(薬)学総合研究科, 名誉教授 2003 – 2012: Okayama University, Advanced Science Research Center, Professor, 自然生命科学研究支援センター, 教授 2010: 岡山大学, 自然生命科学研究センター, 教授 2004: 岡山大学, 生命科学研究センター, 教授 2001 – 2002: 岡山大学, 大学院・医歯学総合研究科, 助教授 … More 1989 – 2000: 岡山大学, 医学部, 助教授 1992: 岡山大, 医学部, 助教授 1988: 岡山大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Experimental pathology / General medical chemistry / Genome biology / Biological Sciences / Cell biology Except Principal Investigator Urology / Hygiene / Hygiene / Environmental impact assessment/Environmental policy / Ophthalmology / Laboratory medicine / Biological Sciences
Keywords	Principal Investigator 核マトリックス / 核骨格 / MAR / SAR / DNA結合タンパク質 / hnRNP / Nuclear scaffold / クロマチン構造 / トポイソメラーゼII / DNAトポイソメラ-ゼII … More / 染色体 / Nuclear matrix / AT-tracts / DNA binding protein / ATトラクト / RNA processing / nuclear matrix / nuclear scaffold / ribonucleoprotein / RNAプロセシング / リボ核タンパク質 / DNA-binding protein / Transcription / Super coiled DNA / DNA結合蛋白質 / RNA転写 / 超らせんDNA / 分化 / 発生 / 発生・分化 / 発現制御 / 酵素 / ゲノム / 遺伝子 / ゲノム塩基配列 / アイソコア構造 / トピイソメアラーゼII / 初代培養 / 遺伝子発現 / 神経細胞分化 / RNA合成 / hnRNP複合体 … More Except Principal Investigator 核マトリックス / 化学療法 / DNAトポイソメラーゼ / 薬剤耐性 / 過酸化水素 / Antioxidants / 抗酸化物質 / ローソン / ヒドロキノン / トポイソメラーゼII / クロマチン / ヘテロクロマチン / エトポシド / CPT-11 / スーパーコイル化因子 / DNAトポイソメラ-ゼ / 超ラセン / Screening / Oxidative stress / Risk assessment / Chemical compounds / CAT assay / Transformants / Catalase mutant gene / 浸出水と放流水 / クメンハイドロペルオキサイド / ヘンナ製品 / ジチオトレイトール / スクリーニング / 酸化的ストレス / 有害性評価 / 化学物質 / CATアッセイ / 形質転換菌 / カタラーゼ遺伝子 / Inorganic heavy metal compounds / Cytotoxicity / Hydrogen peroxide / Catalase mutant genes / Hypocatalasemic mice / Acatalasemic mice / Catalase mutant E coli strains / DNA酸化損傷 / ニトロベンゼン / カタラーゼ阻害剤 / ヒポカタラセミクマウス / アカタラセラミクスマウス / 無機重金属化合物 / 細胞毒性 / カタラーゼ変異遺伝子 / ヒポカタラセミアマウス / アカタラセミアマウス / カタラーゼ欠損大腸菌 / topoisomerase II / Matrix associated region / Genome imprinting / Mini-satellite sequence / Nucleosome / Chromatin remodeling / GAGA factor / Active chromatin / HMG1 / DNA複製中心 / MCMタンパク質 / 染色体凝縮 / 反復配列 / Dis2ホスファターゼ / 核骨格 / インプリンティング / ISWIタンパク / 核骨格附着領域(MAR) / ゲノムインプリンティング / GGA反復配列 / ヌクレオソーム / クロマチンリモデリング / GAGA因子 / 活性クロマチン / 多剤耐性 / カンプトテシン / 環境影響評価 / 酸化ストレス / 美白クリーム / プロテオーム / カタラーゼ遺伝子変異マウス / 生体影響評価 / 化学物質の生体影響評価 / レスベラトロール / アポトーシス / カタラーゼ / 初代培養肝細胞 / 癌化 / 前立腺 / Bip/GRP78 / 前立腺分化 / GRP78 / BiP / Akt / Ras-GTP / Ras / 不死化関連遺伝子 / 膜小胞輸送 / スプライスバリアント / アンフィファイジン / 色素上皮細胞 / 膜輸送と輸送タンパク質 / エンドソーム / 生体膜 / エンドサイトーシス / 網膜色素上皮細胞 / 網膜 / 眼細胞生物学 / 眼生化学・分子生物学 / ビオチン標識プローブ / 抗ssDNA抗体 / 抗dsDNA抗体 / 高感度化学発光法 / 抗MAR自己抗体 / Matrix Attachment Region DNA(MAR) / MAR自己抗体 / Matrix Attachment Region (MAR) / 蛍光標識核免疫染色 / 抗DNA抗体 / ビオチン標識MARプローブ / 高感度化学発光ELISA法 / RNA helicase A / matrix attachment region(MAR) / 自己免疫疾患 / 遺伝子発現制御 / 染色体分配 / トポイソメラーゼ / タンパク質複合体 / 核構造 / 細胞分化 / 神経細胞 / 転写誘導 / ゲノム機能制御 / 遺伝子発現 / ゲノム機能 / アクチン関連タンパク質 / 細胞核 / 新種微生物 / ナノバクテリア / バイオフィルム / 歯石 / 腎結石 / MST-16 / VP-16 / セントロメア抗原タンパク質 / 核内移行 / 核骨格タンパク質 / DNA超らせん化因子 / 自己複製配列(ARS) / DNA結合タンパク質 / 湾曲DNA / ス-パ-コイル / DNAトポロジ- / トポロジー / DNAトポイソラーゼ Less

Roles of type II DNA topoisomerase in the interaction of distant genomic sitesPrincipal Investigator
- Principal Investigator
  
  TSUTSUI KEN
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genome biology
- Research Institution
  Okayama University
Risk assessment of environmental oxidative chemicals using catalase mutant primary cultured hepatocytes
- Principal Investigator
  
  WANG Da-hong
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental impact assessment/Environmental policy
- Research Institution
  Okayama University
The molecular function of immortalization-related genes in the regulation of Oncogenic Ras and prostatic carcinogenesis.
- Principal Investigator
  
  KUMON Hiromi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Okayama University
Studies on the function of amphiphysin Ir in retinal pigment epithelium
- Principal Investigator
  
  HOSOYA Osamu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Okayama University
DEVELOPMENT AND ITS PRACTICAL USE OF SCREENING METHODS ON HAZARD IDENTIFICATION USING CATALASE MUTANT GENE AS A PREDICTIVE INDEX
- Principal Investigator
  
  WANG Da-hong
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Okayama University
Researches on intra-nuclear architecture and regulation of chromatinfunction
- Principal Investigator
  
  HARATA Masahiko
- Project Period (FY)
  2004 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
高感度化学発光法により検出される抗MAR自己抗体の新たな知見
- Principal Investigator
  
  唐下博子
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University
日本人の腎結石から分離した新種ナノバクテリアに関する多面的解析
- Principal Investigator
  
  KUMON Hiromi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Okayama University
DEVELOPMENT OF RISK ASSESSMENT METHODS ON HAZARD IDENTIFICATION USING CATALASE MUTANT GENE AS A PREDICTIVE INDEX
- Principal Investigator
  
  WANG Da-hong
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  OKAYAMA UNIVERSITY
染色体脱凝縮により活性する遺伝子群のゲノム局在様式と発現のメカニズムPrincipal Investigator
- Principal Investigator
  
  筒井研
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Okayama University
染色体の高次構造変化を伴う遺伝子発現調節機構の解明Principal Investigator
- Principal Investigator
  
  筒井研
- Project Period (FY)
  1999 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
DNA binding mechanism of nuclear matrix proteins that recognize short AT-tractsPrincipal Investigator
- Principal Investigator
  
  TSUTSUKI Ken
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Okayama University
Constitution of the Sites for execution of nuclear functions
- Principal Investigator
  
  HIROSE Susumu
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Institute of Genetics
Survey of autoantibodies against SP120, a multifunctional ribonucleoprotein, and their application to functinal analysisPrincipal Investigator
- Principal Investigator
  
  TSUTSUI Ken
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Okayama University
核骨格の再構成系を用いた核機能の解析Principal Investigator
- Principal Investigator
  
  筒井研
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Okayama University
DNAトポイソメラーゼ機能の分子生物学的研究と癌化学療法への応用
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
DNAトポイソメラーゼ機能の分子生物学的研究と癌化学療法への応用
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
DNAトポイソメラ-ゼ機能の分子生物学的研究とその癌化学療法への応用
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
核骨格と核骨格付着領域DNAの相互作用から見た染色体構造Principal Investigator
- Principal Investigator
  
  筒井研
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
DNAトポイソメラ-ゼを標的とした癌化学療法開発のための基礎的研究
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
核骨格と核骨格付着領域DNAの相互作用から見た染色体構造Principal Investigator
- Principal Investigator
  
  筒井研
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Okayama University
染色体ドメインの機能構造
- Principal Investigator
  
  水野重樹
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
DNAトポイソメラーゼ(トポ)を標的とした癌化学療法開発のための基礎的研究
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
Roles of the Nuclear Scaffold and Higher Order DNA Structure in TranscriptionPrincipal Investigator
- Principal Investigator
  
  TSUTSUI Ken
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Okayama University
DNAトボイソメラーゼを標的とした癌化学療法のための基礎的研究
- Principal Investigator
  
  安藤俊夫
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Meiji Pharmaceutical University

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All Journal Article Presentation Book Patent

[Book] Catalase gene mutant mice; Acatalasemic and hypocatalasemin mice. In “Advances in Medicine and Biology”2013
- Author(s)
  Wang, D.H., Ogino, K., Tsutsui, K., Sano, K., Masuoka, N., Sugiyama, H., Miyazaki, M., Fujita, H., Taketa, K., Ogata, M.
- Publisher
  NOVA Science publishers, Inc., New York
- Data Source
  KAKENHI-PROJECT-23310133
[Journal Article] Behavior tests and immunohistochemical retinal response analyses in RCS rats with subretinal implantation of Okayama-University-type retinal prosthesis2013
- Author(s)
  Alamusi, Matsuo T., Hosoya O., Tsutsui K.M., Uchida T
- Journal Title
  
  Journal of Artificial Organs
  
  Volume: 16 Issue: 3 Pages: 343-351
- DOI
  10.1007/s10047-013-0697-1
- NAID
  120005526620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310133
[Journal Article] Resveratrol Inhibited Hydroquinone- induced Cytotoxicity in Mouse Primary Hepatocytes2012
- Author(s)
  Wang DH, Ootsuki Y, Fujita H, Miyazaki M, Yie Q, Tsutsui K, Sano K, Masuoka N, Ogino K
- Journal Title
  
  Int. J. Environ Res & Public Health
  
  Volume: 9 Pages: 3354-3364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310022
[Journal Article] Resveratrol Inhibited Hydroquinone-induced Cytotoxicity in Mouse Primary Hepatocytes.2012
- Author(s)
  (Wang DH), Otsuki Y, Fujita H, Miyazaki M, Yie Q, Tsutsui K, Sano K, Masuoka N, Ogino K.
- Journal Title
  
  Int J Environ Res & Public Health
  
  Volume: 9 Issue: 9 Pages: 3354-3364
- DOI
  10.3390/ijerph9093354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310022, KAKENHI-PROJECT-23310133, KAKENHI-PROJECT-24592263
[Journal Article] A new risk assessment method for evaluation of oxidative chemicals using catalase mutant mouse primary hepatocytes2011
- Author(s)
  Wang DH, Ishikawa Y, Miyazaki M, Fujita H, Tsutsui K, Sano K, Masuoka N, Ogino K
- Journal Title
  
  Health
  
  Volume: 3 Pages: 288-291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310022
[Journal Article] Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain2011
- Author(s)
  Tsutsui, K.M., Sano, K., Hosoya, O., Miyamoto, T., Tsutsui, K
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39 (12) Pages: 5067-5081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310133
[Journal Article] Nuclear protein LEDGF/p75 recognizes supercoiled DNA by a novel DNA-binding domain2011
- Author(s)
  Tsutsui, K.M.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 39 Pages: 5067-5081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310133
[Journal Article] Evaluation of Pyrogallol-induced Cytotoxicity in Catalase-mutant Escherichia coli and Mutagenicity in Salmonella typhimurium.2010
- Author(s)
  Takemura Y, Wang DH, Sauriasari R, Horita M, Tsutsui K, Sano K, Masuoka N, Takigawa T, Takaki J, Ogino K.
- Journal Title
  
  Bulletin of Environmental Contamination and Toxicology 84
  
  Pages: 347-350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310022
[Journal Article] Evaluation of Pyrogallol-induced Cytotoxicity in Catalase-mutant Escherichia coli and Mutagenicity in Salmonella typhimurium. Bulletin of Environmental Contamination and Toxicology2010
- Author(s)
  Takemura Y, Wang DH, Sauriasari R, Horita M,Tsutsui K, Sano K, Masuoka N, Takigawa T, Takaki J, Ogino K
- Journal Title
  
  Bull. Environ. Contam. Toxicol
  
  Volume: 84 Pages: 347-350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21310022
[Journal Article] 網膜リボンシナプスの情報伝達と網膜特異的Amphiphysin-Irの機能2009
- Author(s)
  筒井公子, 他
- Journal Title
  
  Acta Anatomica Nipponica 84(Supplement)
  
  Pages: 86-86
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] 網膜リボンシナプスの情報伝達と網膜特異的Amphiphysin Irの機能2009
- Author(s)
  筒井公子、細谷修
- Journal Title
  
  Acta Anatomic Nipponica 84
  
  Pages: 86-86
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] 人工網膜からみた網膜神経細胞の機能2009
- Author(s)
  松尾俊彦、内田哲也、財部健一、細谷修、筒井公子
- Journal Title
  
  Acta Anatomic Nipponica 84
  
  Pages: 87-87
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] Development of a new assay for evaluation of L-3, 4-dihydroxyphenylalanine cytotoxicity in catalase mutant Escherichia coli.2008
- Author(s)
  Wang DH, Horita M, Tsutsui K, Sano K, Sauriasari R, Masuoka N, Takemura Y, Takigawa T, Takaki J, Ogino K.
- Journal Title
  
  Environmental Toxicology and Chemistry (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Glial reaction to photoelectric dye-based retinal prostheses implanted in subretinal space of rats2008
- Author(s)
  Takayuki Tamaki, Toshihiko Matsuo, Osamu Hososya, Kimiko M Tsutsui, Tetsuya Uchida, Kazuo Okamoto, Akihiko Uji, Hiroshi Ohtsuki
- Journal Title
  
  Journal of Artificial Organs 11
  
  Pages: 38-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] Development of a new assay for evaluation of L-3, 4-dihydroxyphenylalanine cytotoxicity in catalase mutant Escherichia coli.2008
- Author(s)
  Wang DH, Horita M, Tsutsui K, Sano K. Sauriasari R, Masuoka N, Takemura Y, Takigawa T. Takaki J. Ogino K.
- Journal Title
  
  Environmental Toxicology and Chemistry (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Development of a new assay for evaluation of L-3,4-dihydroxy- phenylalanine cytotoxicity in catalase mutant Escherichia coli2008
- Author(s)
  Wane, DH, Horita, M., Tsutsui, K., Sano, K., Sauriasari, R., Masuoka, N., Takemura, Y., Takigawa, T., Takaki, J., Ogino, K
- Journal Title
  
  Environmental Toxicology and Chemistry (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Topoisomerase IIb activates a subset of neuronal genes that are repressed in AT-rich genomic environment2008
- Author(s)
  Sano, K., Miyaji-Yamaguchi, M., Tsutsui, KM., Tsutsui, K
- Journal Title
  
  PLoS ONE 3(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] Cytotoxicity of lawsone and cytoprotective activity of antioxidants in catalase mutant Escherichia coli.2007
- Author(s)
  Sauriasari R, Wang DH, Takemura Y, Tsutsui K, Masuoka N, Sano K, Horita M, Wan BL, 0gino K.
- Journal Title
  
  Toxicology (In press)
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Cytotoxicity of lawsone and cytoprotective activity of antioxidants in catalase mutant Escherichia coli2007
- Author(s)
  Sauriasari, R., Wang, DH, Takemura, Y., Tsutsui, K., Masuoka, N., Sano, K., Horita, M., Wang, BL, Ogino, K
- Journal Title
  
  Toxicology 235
  
  Pages: 103-111
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Amphiphysin Ir participates in receptor-mediated endocytosis in ARPE-192007
- Author(s)
  Osamu Hosoya, Kimiko M Tsutsui, Ken Tsutsui
- Journal Title
  
  Neuroscience Research 58/S1
- Data Source
  KAKENHI-PROJECT-19791268
[Journal Article] Protective ability of enzymatic and non enzymatic antioxidants against dithiothreitol-induced cytotoxicity on catalase mutant Escherichia coli2007
- Author(s)
  Sauriasari R, Wang DH, Takemura Y, Tsutsui K, Masuoka N, Sano K, Wang BL, Horita M, Ogino K
- Journal Title
  
  Journal of Preventive Medicine 2
  
  Pages: 36-41
- NAID
  40016137834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Cytotoxicity of lawsone and cytoprotective activity of antioxidants in catalase mutant Escherichia coli.2007
- Author(s)
  Sauriasari R, Wang DH, Takemura Y, Tsutsui K, Masuoka N, Sano K, Horita M, Wang BL, Ogino K.
- Journal Title
  
  Toxicology 235
  
  Pages: 103-111
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Cytotoxicity of lawsone and cytoprotective activity of antioxidants in catalase mutant Escherichia coli2007
- Author(s)
  Sauriasari R, Wang DH, Takemura Y, Tsutsui K, Masuoka N, Sano K, Horita M. Wang BL, Ogino K
- Journal Title
  
  Toxicology 235
  
  Pages: 103-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Correlations between scaffold/matrix attachment region (S/MAR) binding activity and DNA duplex destabilization energy2006
- Author(s)
  Bode, J., Winkelmann, S., Gotze, S., Spiker, S., Tsutsui, K., Bi, C., Prashanth, A.K., Benham, C
- Journal Title
  
  J. Mol. Biol 358
  
  Pages: 597-613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] Expression dynamics and functional implications for DNA topoisomerase II β in the brain2006
- Author(s)
  Tsutsui K他
- Journal Title
  
  Anat.Sci.Int. (In press)
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] Expression dynamics and functional implications of DNA topoisomerase IIb in the brain2006
- Author(s)
  Tsutsui, KM., Sano, K., Hosoya, O., Tsutsui, K
- Journal Title
  
  Anat. Sci. Int 81
  
  Pages: 156-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] 核マトリックスとRNAを結ぶもの2006
- Author(s)
  筒井研, 河野真二
- Journal Title
  
  蛋白質核酸酵素 51巻,14号
  
  Pages: 1964-1969
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] Expression dynamics and functional implications of DNA topoisomerase IIβ in the brain. (Review)2006
- Author(s)
  Tsutsui, K. et al.
- Journal Title
  
  Anatomical Science International 81
  
  Pages: 156-163
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] Involvement of oxidative stress in hydroquinone-induced cytotoxicity in catalase-deficient Escherichia coli mutants.2005
- Author(s)
  Horita M, Wang_DH, Tsutsui K, Sano K, Masuoka N, Kira S.
- Journal Title
  
  Free Radical Research 39・10
  
  Pages: 1035-1041
- Data Source
  KAKENHI-PROJECT-17390173
[Journal Article] Dynamic view of the nuclear matrix2005
- Author(s)
  Tsutsui K. et al.
- Journal Title
  
  Acta Med.Okayama (in press)
- NAID
  120002312554
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] Dynamic view of the nuclear matrix2005
- Author(s)
  Tsutsui K 他
- Journal Title
  
  Acta Med.Okayama 59
  
  Pages: 113-120
- NAID
  120002312554
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] Large-scale identification and mapping of nuclear matrix-attachment regions in the distal imprinted domain of mouse chromosome 72004
- Author(s)
  Purbowasito, W., Suda, C., Yokomine, T., Zuair, M., Sado, T., Tsutsui, K., Sasaki, H
- Journal Title
  
  DNA Res 11
  
  Pages: 391-407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16084201
[Journal Article] 核マトリックスのダイナミズム2004
- Author(s)
  箇井研, 佐野訓明, 筒井公子
- Journal Title
  
  細胞核のダイナミクス(シュプリンガー・フェアラーク東京)
  
  Pages: 169-176
- Data Source
  KAKENHI-PROJECT-16084201
[Patent] 負の超らせんDNA 結合ドメイン2013
- Inventor(s)
  筒井研,他3名
- Industrial Property Rights Holder
  国立大学法人, 岡山大学
- Industrial Property Rights Type
  特許
- Acquisition Date
  2013-09-27
- Data Source
  KAKENHI-PROJECT-23310133
[Patent] 負の超らせんDNA結合ドメイン2007
- Inventor(s)
  筒井研,他3名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2007-190612
- Filing Date
  2007-07-23
- Data Source
  KAKENHI-PROJECT-16084201
[Presentation] II 型DNA トポイソメラーゼの核内動態と遺伝子制御 (シンポジウム : 細胞核内構造体の構築原理と高次生命機能)2013
- Author(s)
  筒井研
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] II型DNAトポイソメラーゼによる神経特異的遺伝子の発現制御機構2013
- Author(s)
  宮地まり、佐野訓明、古田良平、細谷　修、筒井公子、筒井　研
- Organizer
  第12回　細胞核ダイナミクス研究会
- Place of Presentation
  ホテルおかだ（神奈川県足柄下郡箱根町）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] DNAトポイソメラーゼIIβによる遺伝子制御と核構造2013
- Author(s)
  古田良平、宮地まり、佐野訓明、細谷　修、筒井公子、筒井　研
- Organizer
  第36回　日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] II型DNAトポイソメラーゼの核内動態と遺伝子制御　(シンポジウム：細胞核内構造体の構築原理と高次生命機能)2013
- Author(s)
  筒井　研
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] SBP75の選択的DNA高次構造認識2013
- Author(s)
  佐野訓明、山崎和彦、筒井公子、筒井　研
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] DNAトポイソメラーゼIIβのC末端領域による酵素反応制御機構の解析2013
- Author(s)
  河野真二、加藤佑梨、小野田彰久、木山和子、池田正五、筒井公子、筒井　研
- Organizer
  第86回　日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] II型トポイソメラーゼによる核内構造変化と遺伝子発現制御2012
- Author(s)
  宮地まり、古田良平、佐野訓明、細谷　修、筒井公子、筒井　研
- Organizer
  第30回　染色体ワークショップ・第11回　細胞核ダイナミクス研究会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] DNA Topoisomerase IIbeta Mediates Distal Genomic Interactions in Terminal differentiation of Neurons.2012
- Author(s)
  Furuta, R., Miyaji, M., Sano, K., Tsutsui, K.M., Tsutsui, K.
- Organizer
  BIT’s 3rd Annual World Congress of NeuroTalk-2012.
- Place of Presentation
  Beijing International Convention Center, Beijing, China
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] SP120/SAF-A/hnRNP UのMAR認識機構とDNA構造変化2012
- Author(s)
  宮地まり、古田良平、筒井公子、筒井研
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] Risk assessment of environmental oxidative chemicals using catalase mutant primary cultured hepatocytes.2012
- Author(s)
  (Dahong Wang), Masahiro Miyazaki, Hirofumi Fujita, Ken Tsutsui, Kuniaki Sano, Noriyoshi Masuoka, Keiki Ogino
- Organizer
  The American Public Health Association's 140th Annual Meeting and Exposition.
- Place of Presentation
  The Moscone Convention Center West, San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] DNA 高次構造と遺伝子発現制御バイオメディカル研究部門セミナー2012
- Author(s)
  筒井研
- Place of Presentation
  産業技術総合研究所(筑波
- Year and Date
  2012-12-26
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] DNAトポイソメラーゼIIβはC末端領域にある新規ドメインを介してRNAにより制御されている2012
- Author(s)
  小野田彰久、木山和子、細谷修、佐野訓明、筒井研、筒井公子
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] RG-domain of hnRNP U/SAF-A/SP120 is Essential for Its MAR-specific DNA-binding Activity.2012
- Author(s)
  Miyaji, M., Furuta, R., Tsutsui, K.M., Tsutsui, K.
- Organizer
  BIT’s 3rd Annual World Congress of NeuroTalk-2012.
- Place of Presentation
  Beijing International Convention Center, Beijing, China
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] 初代培養肝細胞におけるヒドロキノンの影響とレスベラトロールの抑制効果2012
- Author(s)
  叶欽霞、汪達紘、大月芳恵、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、益岡典芳、荻野景規
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都大学吉田キャンパス
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] Induced Expression of Neuroal Genes in Terminal Differentiation: Essential Roles of DNA Topoisomerase IIbeta.2012
- Author(s)
  Tsutsui, K.M., Miyaji, M., Sano, K., Furuta, R., Tsutsui, K.
- Organizer
  BIT’s 3rd Annual World Congress of NeuroTalk-2012.
- Place of Presentation
  Beijing International Convention Center, Beijing, China
- Invited
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] II型トポイソメラーゼによる遠隔ゲノム部位間の相互作用2012
- Author(s)
  古田良平、宮地まり、佐野訓明、筒井公子、筒井　研
- Organizer
  第30回　染色体ワークショップ・第11回　細胞核ダイナミクス研究会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] Induced Expression of Neuroal Genes in Terminal Differentiation : Essential Roles of DNA Topoisomerase Iibeta2012
- Author(s)
  Tsutsui, K.M
- Organizer
  BIT's 3rd Annual World Congress of NeuroTalk-2012
- Place of Presentation
  Beijing International Convention Center, Beijing, China
- Year and Date
  2012-05-20
- Invited
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] DNAトポイソメラーゼIIβによる遠隔ゲノム部位間の相互作用と遺伝子発現制御2012
- Author(s)
  古田良平、宮地まり、佐野訓明、筒井公子、筒井研
- Organizer
  第35回　日本分子生物学会年会
- Place of Presentation
  マリンメッセ福岡(福岡県)
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] Risk assessment of environmental oxidative chemicals using catalase mutant primary cultured hepatocytes2012
- Author(s)
  Wang DH, Miyazaki M, Fujita H, Tsutsui K, Sano K, Masuoka N, Ogino K
- Organizer
  The American Public Health Association's 140th Annual Meeting and Exposition, The Moscone Convention Center West
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2012-10-29
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] 低カタラーゼ活性マウスの初代培養肝細胞を用いた環境化学物質評価法の開発(第2報)2011
- Author(s)
  大月芳恵、汪達紘、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、瀧川智子、荻野景規
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学旗の台キャンパス
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] Transcriptional Induction of Neuronal Genes by Targeted Action of DNA Topoisomerase II・2011
- Author(s)
  Tsutsui, K.M.
- Organizer
  Advances in DNA Topoisomerase and Chromosome Dynamics
- Place of Presentation
  Academia Sinica, Taipei, Taiwan
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] 低カタラーゼ活性マウスの初代培養肝細胞を用いた環境化学物質評価法の開発 (第2報)2011
- Author(s)
  大月芳恵、汪達紘、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、瀧川智子、荻野景規
- Organizer
  第81回日本衛生学会学術総会
- Place of Presentation
  昭和大学旗の台キャンパス
- Year and Date
  2011-03-26
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] Transcriptional Induction of Neuronal Genes by Targeted Action of DNA Topoisomerase Iiβ2011
- Author(s)
  Tsutsui, K.
- Organizer
  Advances in DNA Topoisomerase and Chromosome Dynamics
- Place of Presentation
  Academia Sinica (Taipei)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] Regulatory roles of DNA topoisomerase IIβin the developing cerebellar neurons2011
- Author(s)
  Tsutsui, K.M.
- Organizer
  Fourth International Congress of the Society for Research on the Cerebellum
- Place of Presentation
  東京大学山上会館(東京都)
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PROJECT-23310133
[Presentation] カタラーゼ括性の異なるマウスの初代培養肝細胞に及ぼすヒドロキノンの影響2010
- Author(s)
  大月芳恵、汪達紘、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、瀧川智子、荻野景規
- Organizer
  第8回日本予防医学会学術総会
- Place of Presentation
  石川県立音楽堂交流ホール
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] カタラーゼ活性の異なるマウスの初代培養肝細胞に及ぼすヒドロキノンの影響2010
- Author(s)
  大月芳恵、汪達紘、石川靖夫、藤田洋史、宮崎正博、筒井研、佐野訓明、瀧川智子、荻野景規
- Organizer
  第8回日本予防医学会学術総会
- Place of Presentation
  石川県立音楽堂交流ホール
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] 低カタラーゼ活性マウスの初代培養肝細胞を用いた環境化学物質評価法の開発(第1報)2010
- Author(s)
  汪達紘、石川靖夫、宮崎正博、藤田洋史、筒井研、佐野訓明、益岡典芳、瀧川智子、高木二郎、荻野景規
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台市国際センター
- Data Source
  KAKENHI-PROJECT-21310022
[Presentation] 網膜リボンシナプスの情報伝達と網膜特異的Amphiphysin-Irの機能2009
- Author(s)
  筒井公子, 他
- Organizer
  第114回日本解剖学会総会・全国学術集会
- Place of Presentation
  岡山理科大学
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19791268
[Presentation] 網膜リボンシナプスの情報伝達と網膜特異的Amphiphysin Irの機能2009
- Author(s)
  筒井公子他
- Organizer
  第114回日本解剖学会総会・全国学術集会
- Place of Presentation
  岡山理科大学
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19791268
[Presentation] カタラーゼ変異遺伝子を導入した大腸菌におけるローソンによる細胞毒性と抗酸化物質の抑制作用。2007
- Author(s)
  ラニサウリアサリ、汪達紘、竹村洋子、筒井研、益岡典芳、佐野訓明、筒井公子、堀田昌子、王炳玲、荻野景規
- Organizer
  第18回中国四国生体ラジカル研究会
- Place of Presentation
  岡山理科大学
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-17390173
[Presentation] クロマチン高次構造による遺伝子制御2007
- Author(s)
  筒井研, 他
- Organizer
  第30回日本分子生物学会年会第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-16084201
[Presentation] DNA高次構造と遺伝子発現制御
- Author(s)
  筒井　研
- Organizer
  バイオメディカル研究部門セミナー
- Place of Presentation
  産業技術総合研究所（茨城県）
- Data Source
  KAKENHI-PROJECT-23310133

1. HIROSE Susumu (90022730)

# of Collaborated Projects: 6 results

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2. SANO Kuniaki (00294405)

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# of Collaborated Products: 9 results

TSUTSUI Ken 筒井 研

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染色体脱凝縮により活性する遺伝子群のゲノム局在様式と発現のメカニズムPrincipal Investigator

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染色体の高次構造変化を伴う遺伝子発現調節機構の解明Principal Investigator

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DNA binding mechanism of nuclear matrix proteins that recognize short AT-tractsPrincipal Investigator

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Survey of autoantibodies against SP120, a multifunctional ribonucleoprotein, and their application to functinal analysisPrincipal Investigator

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核骨格の再構成系を用いた核機能の解析Principal Investigator

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TSUTSUI Ken 筒井研