TODOROKI Takeshi 轟健

… Alternative Names

轟健トドロキタケシ

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Researcher Number	70114105
External Links
Affiliation (based on the past Project Information) *help	2005: 筑波大学, 大学院人間総合科学研究科, 助教授 2004 – 2005: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Associate Professor, 大学院・人間総合科学研究科, 助教授 1994 – 2003: 筑波大学, 臨床医学系, 助教授 2002: 筑波大学, 臨床医学系, 助教師 1995: 筑波大学, 臨床医学系・外科, 助教授 1988 – 1990: 筑波大学, 臨床医学系, 講師
Review Section/Research Field	Principal Investigator Digestive surgery / 広領域 Except Principal Investigator Biological Sciences / Pathological medical chemistry / Gastroenterology / Gastroenterology / Pathological medical chemistry
Keywords	Principal Investigator DIVEMA / 肝微小循環 / SOD / SB209670 / 肝阻血再灌流障害 / 肝阻血再潅流障害 / sinusoid perfusion / endothelin receptor antagonist / ischemia-reperfusion injury / 白血球膠着 … More / エンドセリン拮抗剤 / 白血球動態 / Copolymer / gallbladder carcinogenesis / signal transduction / oncogene / mucin glycoprotein / animal model / gallbladder carcinoma / 再発 / ムチン / MUC 1 / MY.IE12 / 粗血再灌流障害 / 類洞内皮 / 肝転移モデル / 悪性度 / 接着分子 / 糖転移酵素 / MUC 1ムチン / 再発形式 / 予後 / E-cadherin / GalNAcT3 / MUC1ムチン / MY.1E.12 / pT2胆嚢癌 / 腫瘍生物学 / 転移・浸潤 / 発現様式 / 免疫染色 / モノクローナル抗体 / MUC1 / 粘液形質 / 胆嚢癌 / liver dysfunction / leukocyte adhesion / central venous flow / liver microcirculation / 肝酵素 / 胆汁排泄 / 中心静脈血行 / エンドセリン拮抗薬 / 肝機能障害 / 類洞血流 / 中心静脈血流 / leukokinetics / liver microcirculatin / 肝類洞灌流 / 肝微小循環動態 / エンドセリン受容体拮抗ペプチド / エンドセリン / SOD-DIVEMA / エンドセリン受容体阻害剤 / 類洞灌流 / 肝虚血再灌流障害 / Hepatic sinusoid / Leukocyte kinetics / Hepatic microcirculation / SOD-DIVEMA conjugate / Hepatic reperfusion injury / 類洞血行 / Superoxide Dismutase (SOD) / 肝類洞 / SOD-DIVEMA結合体 / Microcirculation of the liver / SOD-Polymer hybrid / Reperfusion liver injury / DIVEMA-SOD結合体 / 生体内エピルミネッセンス顕微鏡 / 高分子-SODハイブリット / BRM(Biologocal Response Modifier) / 腹膜播種性転移 / コポリマー / 高分子キャリア / DIVEMA-ADR結合体 / 抗腫瘍効果増強と毒性低下 / アドリアマイシン / Drug Delivery System / 合成ポリアニオン … More Except Principal Investigator 胆道がん / 肝内胆管がん / 肝吸虫感染 / 肝臓がん / CGH / adenovirus / gene therapy / gallbladder cancer / アデノウイルス / 遺伝子治療 / 胆嚢癌 / 胆道癌 / GSTM1 / COX-2 / 胆管癌 / 症例・対照研究 / ミクロサテライト不安定性 / ゲノム不安定性 / biliary tract cancer / XRCC1 / ニトロサミン / GSTT1 / GST / CYP2A6 / インド / 遺伝子多型 / integrin / bile duct cancer / biliary cancer / コクサッキー・アデノウイルス受容体 / インテグリン / Polymorphism / Case control study / liver fluke / Infection / India / Thailand / Biliary tract cancer / 細胞増殖 / 蛍光ディファレンシャルディスプレイ法 / ハムスターモデル / 胆嚢がん細胞株 / プロテインキナーゼA調節サブユニット1 / 肝吸虫 / 感染症 / タイ王国 / ウラシルホスホリボシルトランスフェラーゼ / ウラシルフォスフォリボシルトランスフェラーゼ / 5-フルオロウラシル / microsatellite instability / genomic instability / intrahepatic cholangiocarcinoma / xanthogranulomatous cholecystitis / gall bladder cancer / 黄色肉芽腫瘍胆襄炎 / がん遺伝子 / 薬剤代謝酵素 / マイクロサテライト不安定性 / 黄色肉芽腫様胆嚢炎 / 胆嚢がん / 1q23 amplification / prognosis / array CGH / DNA microarray / gastric cancer / neuroblastoma / ovarian cancer / 卵巣癌 / 遺伝子 / 難治癌 / マイクロアレイ / 転移 / 浸潤 / 難治がん / 1q23 増幅 / 予後 / アレイCGH / DNAマイクロアレイ / 胃がん / 神経芽腫 / 卵巣がん / hOGG1 / CYP2E1 / 遺伝子異常 / 遺伝子発現 / 霞ヶ浦 / タイ / 寄生虫 / 遺伝子欠失 / 遺伝子増幅 / 胆のうがん Less

タイ寄生虫感染関連胆道がんの症例・対照研究による遺伝子多型の解析
- Principal Investigator
  
  三輪正直
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Experimental Efficacy of Fiber-modified Cancer-selectively Replicating Adenovirus for Gene Therapy of Biliary Cancers
- Principal Investigator
  
  ABEI Masato
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
タイ寄生虫感染関連胆道がんの症例・対照研究による遺伝子多型の解析
- Principal Investigator
  
  三輪正直
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Genetic oncological and molecular epidemiological research on development and progression of human bile duct cancer in Asia
- Principal Investigator
  
  MIWA Masanao
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagahama Institute of Bio-Science and Technology
  University of Tsukuba
タイ王国寄生虫感染関連胆道がんの症例・対照研究による薬物代謝酵素遺伝子多型
- Principal Investigator
  
  三輪正直
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Experimental Analysis and Application of Cancer-selectively Replicating Adenovirus for Gene Therapy of Gallbladder Cancer.
- Principal Investigator
  
  TANAKA Naomi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
タイ国寄生虫感染関連胆道がんの症例・対照研究による薬物代謝酵素遺伝子多型
- Principal Investigator
  
  三輪正直
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Experimental Efficacy of Adenovirus-mediated Gene Therapy for Gallbladder Cancer
- Principal Investigator
  
  ABEI Masato
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
Protection of hepatic microcirculatory disturbance due to the ischemia-reperfusion injuryPrincipal Investigator
- Principal Investigator
  
  TODOROKI Takeshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
Mucin glycoproteins in human gallbladder carcinoma and their biological effects on tumor invasion and metastasis capability.Principal Investigator
- Principal Investigator
  
  TODOROKI Takeshi, 川本徹
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
タイ国寄生虫感染関連胆道がんの症例・対照研究による薬物代謝酵素遺伝子多型
- Principal Investigator
  
  三輪正直
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Genetic oncological and molecular epidemiological research on development and progression of the biliary tract cancer in Asia
- Principal Investigator
  
  MIWA Masanao
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Tsukuba
The effect of TAK-O44 combined with SOD-DIVEMA on ischemia reperfusion liver injury.Principal Investigator
- Principal Investigator
  
  TODOROKI Takeshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
南西アジアと日本に於けるヒト胆道癌の発生・進展に関する遺伝子癌生物学的研究
- Principal Investigator
  
  MIWA Masanao
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Tsukuba
Identification of novel oncogenes invloved in onset and progression of cancers with poor prognosis.
- Principal Investigator
  
  UCHIDA Kazuhiko
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Tsukuba
SDUDIES OF HIGH MOLECULAR SUBSTANCE- SOD CONJUGATE ON PREVENSION OF HEPATIC ISCHEMLA-REPERFUSION INJURY AND HEPATIC MICROCIRCULATIONPrincipal Investigator
- Principal Investigator
  
  TODOROKI Takeshi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  UNIVERSITY OF TSUKUBA
Prevention of reperfusion liver injury by SOD-(DIVEMA) conjugatePrincipal Investigator
- Principal Investigator
  
  TODOROKI Takeshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  University of Tsukuba
合成ポリアニオンによる抗がん剤の効果増強に関する研究Principal Investigator
- Principal Investigator
  
  轟健
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba

All 2003 2002 2001 Other

All Journal Article Book

[Book] 消化器外科12 消化器画像をめぐる話題2002
- Author(s)
  轟健
- Total Pages
  6
- Publisher
  へるす出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] The blood circulation rebuilding and gallbladder cancer exsection to be accompanied with2003
- Author(s)
  T.Todoroki
- Journal Title
  
  Operation 57(2)
  
  Pages: 151-156
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Patterns and predictions of failure after curative resections.2003
- Author(s)
  Todoroki T et al.
- Journal Title
  
  Annals of Surgical Oncology 10
  
  Pages: 1176-1183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671279
[Journal Article] 血行再建を伴う胆のう癌切除術2003
- Author(s)
  轟健
- Journal Title
  
  手術 57・2
  
  Pages: 151-156
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Patterns and predictors of failure after curative resections2003
- Author(s)
  Todoroki T et al.
- Journal Title
  
  Annals of Surgical Oncology 10
  
  Pages: 1176-1183
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671279
[Journal Article] Role of platelet-activating factor in hepatectomy with Pringle's maneuver2002
- Author(s)
  T.Todoroki
- Journal Title
  
  Operation 56(9)
  
  Pages: 1291-1296
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Expression of Cyclooxygenase-2 and Prostaglandin E-Receptors in Carcinoma of the Gallbladder : Crucial Role of Arachidonate Metabolism in Tumors with Progress2002
- Author(s)
  T.Todoroki
- Journal Title
  
  Clinical Cancer Research 8
  
  Pages: 1157-1167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Role of platelet-activating factor in hepatectomy with Pringle's maneuver2002
- Author(s)
  轟健
- Journal Title
  
  手術 56・9
  
  Pages: 1291-1296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Synthesis and Properties of Poly[N-(2-hydroxypropyl)methacrylamide] Conjugates of Superoxide Dismutase2002
- Author(s)
  T.Todoroki
- Journal Title
  
  Journal of Bioactive and Compatible Polymers 196・13
  
  Pages: 105-122
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Synthesis and Properties of Poly [N-(2-hydroxyproprl)ethacrylaide] Conjugates of Superoxide Dismutase2002
- Author(s)
  T.Todoroki
- Journal Title
  
  Journal of Bioactive and Compatible Polymers 196(13)
  
  Pages: 105-122
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Expression of Cyclooxygenase-2 in the Subserosal Layer Correlates with Postsurgical Prognosis of Pathological Tumor Stay Carcinoma of the Gallbladder2002
- Author(s)
  T.Todoroki
- Journal Title
  
  Int.J.Cancer 8・4
  
  Pages: 427-434
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Expression of Cyclooxygenase-2 and Prostaglandin E-Receptors in Carcinoma of the Gallbladder : Crucial Role of Arachidonate Metabolism in Tumors with Progres2002
- Author(s)
  T.Todoroki
- Journal Title
  
  Clinical Cancer Research 8
  
  Pages: 1157-1167
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] E-cadherin Expression in the Primary Tumors and Metastatic Lymph Nodes of poorly Differentiated Types of Rectal cancer2002
- Author(s)
  T.Todoroki
- Journal Title
  
  Surgery Today 32(2)
  
  Pages: 123-128
- NAID
  10017517562
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] E-cadherin Expression in the Primary Tamors and Metastatic Lymph Nodes of poorly Differentiated Types of Rectal cancer.2002
- Author(s)
  T.Todoroki
- Journal Title
  
  Surgery Today 32・2
  
  Pages: 123-128
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] DIVEMA(ジビニールエーテル無水マレイン酸共重合体)による癌治療戦略2001
- Author(s)
  轟健, 他
- Journal Title
  
  Drug Delivery System 16(2)
- NAID
  10007335061
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11671208
[Journal Article] Cancer therapentic strategy with DIVEMA2001
- Author(s)
  Takeshi Todoroki, et al.
- Journal Title
  
  Drug Delivery System 16(2)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-11671208
[Journal Article] Endothelin Receptor Antagonist (SB209670) Prevents the Ischemia Reperfusion Liver Injury2001
- Author(s)
  Takeshi Todoroki, et al.
- Journal Title
  
  European Surgical Research
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-11671208
[Journal Article] Expression of Cyclooxygenase-2 in the Subserosal Layer Correlates with Postsurgical Prognosis of Pathological Tumor Stage Carcinoma of the Gallbladder
- Author(s)
  T.Todoroki
- Journal Title
  
  Int.J.Canser 8(4)
  
  Pages: 427-434
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671278
[Journal Article] Fire extinguisher surgery12 A topic around a fire extinguisher image
- Author(s)
  T.Todoroki
- Journal Title
  
  Heath Publication
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671278

1. UCHIDA Kazuhiko (90211078)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. MIWA Masanao (20012750)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. HONJO Satoshi

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. HIRANO Takashi (90357864)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. KAWAMOTO Toru (30282354)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. YOKOYAMA Kazunari (80182707)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. HANAI Shuji (80333483)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. ABEI Masato (20261802)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. OTSUKA Masaaki (80168997)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. TAKADA Yasutsugu (10272197)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. SHODA Junichi (90241827)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. FUKAO Katashi (50091921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAZAKI Hiroshi (30191274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MIYAUCHI Takashi (60222329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. IRIMURA Tatsuro (80092146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TANAKA Naomi (60111530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. HAMADA Hirofumi (00189614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 高橋秀人 (80261808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大野忠夫 (90160580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 渡辺照男 (40037396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 太田力 (10290892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 石川演美 (10026932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 藤田健一 (60281820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 有吉範高 (00243957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 土井幹雄

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KAPOOR V.K.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SRTVATANAKUL ペッチャリン

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TODOROKI Takeshi 轟 健

轟 健 トドロキ タケシ

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Protection of hepatic microcirculatory disturbance due to the ischemia-reperfusion injuryPrincipal Investigator

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Mucin glycoproteins in human gallbladder carcinoma and their biological effects on tumor invasion and metastasis capability.Principal Investigator

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The effect of TAK-O44 combined with SOD-DIVEMA on ischemia reperfusion liver injury.Principal Investigator

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TODOROKI Takeshi 轟健

轟健トドロキタケシ