FUKAMACHI Hiroshi 深町博史

… Alternative Names

深町博史フカマチヒロシ

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Researcher Number	70134450
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2018: 東京医科歯科大学, 大学院医歯学総合研究科, 講師 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 講師 2009 – 2011: 東京医科歯科大学, 大学院・医歯学総合研究科, 講師 2007: 東京医科歯科大学, 医歯学総合研究科, 講師 2007: 東京医科歯科大学, 大学院・医歯学総合研究科, 講師 … More 2005: Tokyo Medical and Dental University, Graduate School of Medicine and Dentistry, Lecturer, 大学院・医歯学総合研究科, 講師 2004: 東京大学, 大学院・理学研究科, 助手 2002 – 2004: 東京大学, 大学院・理学系研究科, 助手 1994 – 1997: 東京大学, 大学院・理学系研究科, 助手 1995: 東京大学, 大学院・理学系研究所, 助手 Less
Review Section/Research Field	Principal Investigator Developmental biology / Biological Sciences / Tumor biology / Morphology/Structure / 生物形態・構造 / Tumor biology Except Principal Investigator Biological Sciences / Morphology/Structure / General surgery
Keywords	Principal Investigator Runx3 / 胃がん / 分化 / 上皮・間充織相互作用 / Wnt / Eph / 増殖 / Pepsinogen / Stomach / Hepatocyte Growth Factor … More / Epithelial-Mesenchymal Interaction / 小腸 / ペプシノゲン / 胃 / 初代培養 / RT-PCR / 角化細胞成長因子 / 肝細胞増殖因子 / がん幹細胞 / haploinsufficiency / 間充織 / マトリゲル / コラーゲンゲル / 腸上皮化生 / 上皮細胞 / ヌードマウス / Wnt3a / R-spondin1 / 分子標的薬 / 分子標的治療 / PDX / 免疫チェックポイント阻害剤 / ｍTOR阻害剤 / スキルス胃がん / tissue culture / Matrigel / epithelial cells / proliferation / differentiation / intestinal metaplasia / gastric tumor / 分化調節 / 胃上皮細胞 / 培養 / 上皮 / Extracellular Matric / Epithelial-mesenchymal interaction / Intestine / Foxl1 gene / Fkh5 gene / プロテオグリカン / EphB / 細胞外基質 / Foxl1遺伝子 / Fkh6遺伝子 / Rat / HGF Activator / Growth / Differentiation / Glandular Stomach / 骨細胞形成因子 / 線維芽細胞成長因子 / グルココルチコイド / ラット / HGFアクティベータ- / 腺胃 / Cathepsin E / Primary Culture / Keratinocyte Growth Factor / 基質 / 増殖因子 / 形態形成 / KGF / 表皮成長因子 / HGF / カテプシンE / ヒト / spheroids / Xenograft / 細胞表面抗原 / sphere / 無血清培養 / FACS / 造腫瘍性 / 幹細胞 / がん細胞の特性 / 腫瘍形成 / 胃ガン / 細胞増殖 / アポトーシス / ノックアウトマウス / がん抑制遺伝子 … More Except Principal Investigator マウス / 卵巣 / 成長因子 / ノックアウト / 転写因子 / SOX2 / 生活習慣 / メチル化 / 胃がん / ステロイドホルモン / ステロイホルモン / 排卵 / 高頻度変異 / ゲノム編集 / クロマチンリモデリング / 腫瘍変異負荷 / DNA損傷 / 外科 / ゲノム / 遺伝子 / トランスレーショナルリサーチ / 分子サブタイプ / ヒストン修飾 / クロマチン再構築 / クロマチン動的変動 / ゲノム編集技術 / 幹細胞 / 癌 / 生殖 / 再構築 / 組織破壊 / 発情ホルモン / IGF-1 / プロモーター / 子宮内膜 / 転写制御 / ホルモン / 細胞死 / 遺伝子発現 / 子宮 / 下垂体 / アポトーシス / 細胞増殖 / エストジェン受容体 / 分化 / カルシュウムチャンネル遺伝子 / トランスジェニックマウス / 緑茶 / IQGAP2 / NOTCH / 血球DNA / E-カドヘリン / マウスモデル / マイクロRNA / 実験動物モデル / DNAメチル化 / エピジェネティクス / 遺伝子トラップ / トランスジェニック / 遺伝子改変マスウ / 組織診断 / 病理形態学 / データベース / 遺伝学的モニタリング / 微生物学的モニタリング / 凍結保存 / 相同組換え / 遺伝子改変マウス / hMLH1遺伝子 / 大腸がん / SOX2遺伝子 / 二次原発がん / PDX1遺伝子 / CDX2遺伝子 / 発生リスク / 生活習慣要因 / PDX1 / 転写調節 / ホメオプロテイン / MUC6 / DNAメチルトランスフェラーゼ / カルシウムチャンネル / BMP-2 / エピジェネティック疫学 / CDX2 Less

Develoment of advanced therapy targeting tumor heterogeneity in refractory cancers
- Principal Investigator
  
  TANAKA Shinji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Medical and Dental University
Mechanism how scirrhous-type gastric cancer is formedPrincipal Investigator
- Principal Investigator
  
  Fukamachi Hiroshi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
Roles of transcription factor Runx 3 in ovarian follicle development and ovulation in mice
- Principal Investigator
  
  Takahashi Sumio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphology/Structure
- Research Institution
  Okayama University
Identification and characterization of human gastric cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  FUKAMACHI Hiroshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Tokyo Medical and Dental University
Regulatory mechanism of breakdown and reconstruction of reproductive organs
- Principal Investigator
  
  TAKAHASHI Sumio
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphology/Structure
- Research Institution
  Okayama University
Integrated cancer research using in vivo models
- Principal Investigator
  
  YAMAMURA Kenichi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Relationship between surrogate markers including DNA methylation and lifestyle factors in gastric carcinogenesis
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Runx3欠失胃上皮細胞を用いた胃がんおよび腸上皮化生形成機構の解析Principal Investigator
- Principal Investigator
  
  深町博史
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Role of Runx3 on the regulation of growth and differentiation and intestinal metaplasia of gastric epithelial cellsPrincipal Investigator
- Principal Investigator
  
  FUKAMACHI Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphology/Structure
- Research Institution
  Tokyo Medical and Dental University
  The University of Tokyo
胃がん抑制遺伝子Runx3の作用機構の解析Principal Investigator
- Principal Investigator
  
  深町博史
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
mecanism of Diffrentiation and Evolution of Parietal and Chief Cells in Vertebrate StomachsPrincipal Investigator
- Principal Investigator
  
  FUKAMACHI Hiroshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物形態・構造
- Research Institution
  The University of Tokyo
宿主・環境要因に着目した消化管がんの二次原発がん発生リスクに関する研究
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Molecular Mechanism of Epithelial-Mesenchymal InteractionsPrincipal Investigator
- Principal Investigator
  
  FUKAMACHI Hiroshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  The University of Tokyo
Molecular Mechanism of Epithelial-Mesenchymal InteractionPrincipal Investigator
- Principal Investigator
  
  FUKAMACHI Hiroshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  The University of Tokyo

All 2019 2018 2017 2016 2015 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] Encyclopedia of Cancer, 4th ed.2016
- Author(s)
  Fukamachi, H.
- Total Pages
  5083
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15K06832
[Book] ヒトの分子遺伝学2011
- Author(s)
  深町博史
- Publisher
  細胞と細胞間情報伝達機構、発生の仕組み
- Data Source
  KAKENHI-PROJECT-22501005
[Book] ヒトの分子遺伝学第4版2011
- Author(s)
  深町博史, 他
- Total Pages
  878
- Publisher
  メディカル・サイエンス・インターナショナル
- Data Source
  KAKENHI-PROJECT-22501005
[Book] 生物の事典2010
- Author(s)
  深町博史、阿形清和、浅川満彦、安部由美子、安藤元一、石原勝敏、一石昭彦、伊野良夫、井上弘一、井上裕介、今井一郎、岩崎俊晴、上田均、大串隆之、大島範子、大西純一、加藤泰建、金子康子、河内美樹、熊澤慶伯、桑野博行、小池文人、鯉淵典之、小柴共一、小林哲也、坂井貴文、佐藤利幸、白山義久、末光隆志、菅原敬、須永伊知郎、相馬早苗、平良眞規、竹内隆、武田洋幸、多田正純、舘鄰、舘野正樹、田中修、田中秀逸、田中実、土屋公幸、戸田年総、戸田任重、二階堂昌孝、野本茂樹、乗越浩司、橋口康之、畠山晋、林進、平野弘道、前島正義、町田
- Total Pages
  560
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-22501005
[Book] 生物学辞典2010
- Author(s)
  深町博史
- Total Pages
  1634
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-22501005
[Book] Gastric cancer, intestinal metaplasia and Runx3. In : Recent Advances in Gastrointestinal Carcinogenesis2006
- Author(s)
  Fukamachi, H
- Publisher
  Transworld Research Network, Kerala, India,(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Book] Gastric cancer, intestinal metaplasia and Runx3. In : Recent Advances in Gastrointestinal Carcinogenesis (eds. H.Bamba and S.Ota)2006
- Author(s)
  Fukamachi, H
- Publisher
  Research Singpost, Kerala, India (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Book] Gastric cancer, intestinal metaplasia and Runx3.(eds. H. Bamba and S. Ota, Recent Advances in Gastrointestinal Carcinogenesis)2006
- Author(s)
  Fukamachi H
- Publisher
  Transworld Res.
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors2019
- Author(s)
  Fukamachi H、Kim SK、Koh J、Lee HS、Sasaki Y、Yamashita K、Nishikawaji T、Shimada S、Akiyama Y、Byeon SJ、Bae DH、Okuno K、Nakagawa M、Tanioka T、Inokuchi M、Kawachi H、Tsuchiya K、Kojima K、Tokino Takashi、Eishi Y、Kim YS、Kim WH、Yuasa Y、Tanaka S
- Journal Title
  
  Journal of Experimental & Clinical Cancer Research
  
  Volume: 38 Issue: 1 Pages: 127-127
- DOI
  10.1186/s13046-019-1121-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K19535, KAKENHI-PROJECT-18K19575, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-18H02791, KAKENHI-PROJECT-15K06832, KAKENHI-PROJECT-16H06279
[Journal Article] Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models.2018
- Author(s)
  Shimada S, Akiyama Y, Mogushi K, Ishigami-Yuasa M, Kagechika H, Nagasaki H, Fukamachi H, Yuasa Y, Tanaka S.
- Journal Title
  
  British Journal of Cancer
  
  Volume: - Issue: 7 Pages: 972-984
- DOI
  10.1038/s41416-018-0008-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-18K19575
[Journal Article] CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells.2016
- Author(s)
  Katsuta, E., Tanaka, S., Mogushi, K., Shimada, S., Akiyama, Y., Aihara, A., Matsumura, S., Mitsunori, Y., Ban, D., Ochiai, T., Kudo, A., Fukamachi, H., Tanaka, H., Nakayama, K., Arii, S., Tanabe, M.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 48 Issue: 2 Pages: 657-669
- DOI
  10.3892/ijo.2015.3299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06832, KAKENHI-PROJECT-15K10035, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-25253081, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25462082, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-26870175, KAKENHI-PROJECT-26462025
[Journal Article] Proteasome activity is required for the initiation of precancerous pancreatic lesions.2016
- Author(s)
  Furuyama, T., Tanaka, S., Shimada, S., Akiyama, Y., Matsumura, S., Mitsunori, Y., Aihara, A., Ban, D., Ochiai, T., Kudo, A., Fukamachi, H., Arii, S., Kawaguchi, Y., Tanabe, M.
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 5 Pages: 27044-27044
- DOI
  10.1262/jrd.2016-005
- NAID
  130005431250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06832
[Journal Article] Proteasome activity is required for the initiation of precancerous pancreatic lesions.2016
- Author(s)
  Furuyama T, Tanaka S, Shimada S, Akiyama Y, Matsumura S, Mitsunori Y, Aihara A, Ban D, Ochiai T, Kudo A, Fukamachi H, Arii S, Kawaguchi Y, Tanabe M.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 27044-27044
- DOI
  10.1038/srep27044
- NAID
  120006775931
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19875, KAKENHI-PROJECT-16K10421
[Journal Article] Runx3 Transcription Factor Regulates Ovarian Functions and Ovulation in Female Mice2016
- Author(s)
  Fumiya Ojima, Yuka Saito, Yukiko Tsuchiya, Daichi Kayo, Syusuke Taniuchi, Maho Ogoshi, Hiroshi Fukamachi, Sakae Takeuchi, Sumio Takahashi
- Journal Title
  
  Journal of Reproduction and Development
  
  Volume: 未定
- NAID
  130005431250
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440167
[Journal Article] Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, possible precursor lesion of diffuse gastric cancer2011
- Author(s)
  Mimata. A., Fukamachi, H., Eishi, Y., and Yuasa, Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 942-950
- NAID
  10029293200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501005
[Journal Article] CD133 is a marker of gland-forming cells in gastric tumors and Sox17 is involved in its regulation2011
- Author(s)
  Fukamachi, H., Shimada, S., Ito, K., Ito, Y., and Yuasa Y.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102 Pages: 1313-1321
- NAID
  10029295180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501005
[Journal Article] CD133 is a marker of gland-forming cells in gastric tumors and Sox17 is involved in its regulation.2011
- Author(s)
  Fukamachi.H., et al.
- Journal Title
  
  Cancer Science
  
  Volume: 102 印刷中
- NAID
  10029295180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501005
[Journal Article] Loss of E-cadherin in mouse gastric epithelial cells induces signet ring-like cells, possible precursor lesion of diffuse gastric cancer2011
- Author(s)
  Mimata. A., Fukamachi, H., et al
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 5 Pages: 942-950
- DOI
  10.1111/j.1349-7006.2011.01890.x
- NAID
  10029293200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501005, KAKENHI-PROJECT-23300342
[Journal Article] CD133 is a marker of gland-forming cells in gastric tumors and Sox17 is involved in its regulation2011
- Author(s)
  Fukamachi, H., et al
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 7 Pages: 1313-1321
- DOI
  10.1111/j.1349-7006.2011.01947.x
- NAID
  10029295180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501005, KAKENHI-PROJECT-23300342
[Journal Article] Loss of Runx3 is a key event in inducing precancerous state of the stomach2011
- Author(s)
  Ito, K., Chuang, L. S. H., Ito, T., Chang, T. L., Fukamachi, H., Salto. Tellez, M., and Ito, Y.
- Journal Title
  
  Gastroenterology
  
  Volume: 140 Pages: 1536-1546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501005
[Journal Article] Claudin-1 has tumor suppressive activity and is a direct target of RUNX3 in gastric epithelial cells2010
- Author(s)
  Chang, T. L., Ito, K., Ko, T. K., Liu, Q., Salto-Tellez, M., Yeoh, K. G., Fukamachi, H., and Ito, Y.
- Journal Title
  
  Gastroenterology
  
  Volume: 138 Pages: 255-265
- NAID
  120006984679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501005
[Journal Article] miR-212 is down-regulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer2010
- Author(s)
  Wada, R., Akiyama, Y., Hashimoto, Y., Fukamachi, H., and Yuasa, Y.
- Journal Title
  
  Int. J. Cancer
  
  Volume: 127 Pages: 1106-1114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501005
[Journal Article] Loss of Runx3 affects ovulation and estrogen-induced endometrial cell proliferation in female mice.2008
- Author(s)
  Sakuma, A., Fukamachi, H., Ito, K., Ito, Y., Takeuchi, S., Takahashi, S.
- Journal Title
  
  Molec. Reprod. Dev. 75
  
  Pages: 1653-1661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370025
[Journal Article] Differentiation in vitro of Runx3-/-p53-/- gastric epithelial cells into intestinal type cells.2008
- Author(s)
  Fukamachi H, Mimata A, Tanaka I, Ito K, Ito Y, Yuasa Y
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 671-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Loss of Runx3 affects ovulation and estrogen-induced endometrial cell proliferation in female mice.2008
- Author(s)
  Sakuma A, Fukamachi H, Ito K, Ito Y, Takeuchi S, Takahashi S
- Journal Title
  
  Mol Reprod Develop. 75
  
  Pages: 1653-1661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Differentiation in vitro of Runx3-/-p53-/- gastric epithelial cells into intestinal type cells2008
- Author(s)
  Fukamachi H, et.al.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 671-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells.2008
- Author(s)
  Jin S-H, Akiyama Y, Fukamachi H, Yanagihara K, Akashi T, Yuasa Y
- Journal Title
  
  Int. J. Cancer 122
  
  Pages: 1040-1046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] RUNX3 attenuates β-catenin/T cell factors in intestinal tumorigenesis.2008
- Author(s)
  Ito K, Lim A.C. -B, Salto-Tellez M, Motoda L, Osato M, Chuang L.S. H, Lee C.W. L, Voon D.C. -C, Koo J.K. W, Wang H, Fukamachi H, Ito Y
- Journal Title
  
  Cancer Cell 14
  
  Pages: 226-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Developmentally regulated expression of matrix metalloproteinases during fetal rat colon morphogenesis.2008
- Author(s)
  Kurakata H, Oka M, Matsubara Y, Niwa T, Utsunomiya H, Fujishiro M, Miki K, Fukamachi H, Kubota S, Ichinose M
- Journal Title
  
  Develop Growth Differ. 50
  
  Pages: 41-48
- NAID
  10020274253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Differentiation in vitro of Runx3-/-p53-/- gastric epithelial cells into intestinal type cells.2008
- Author(s)
  Fukamachi, H., et. al.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 671-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012017
[Journal Article] Differentiation in vitro of Runx3-/-p53-/- gastric epithelial cells into intestinal type cells.2008
- Author(s)
  Fukamachi H, et. al.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 671-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Human Gs・mutant causes pseudohypoparathyroidism type Ia/neonatal diarrhea, a potential cell-specific role of the palmitoylation cycle.2007
- Author(s)
  Makita N, Sato J, Rondard P, Fukamachi H, Yuasa Y, Aldred MA, Hashimoto M, Fujita T, Iiri T
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. 104
  
  Pages: 17424-17429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.2007
- Author(s)
  Tani Y, Akiyama Y, Fukamachi H, Yanagihara K, Yuasa Y
- Journal Title
  
  J. Cancer Res. Clin. Oncol. 133
  
  Pages: 263-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Stroma-derived matrix metalloproteinase (MMP)-2 promotes membrane type 1-MMP-dependent tumor growth in mice.2007
- Author(s)
  Taniwaki K, Fukamachi H, Komori K, Ohtake Y, Nonaka T, Sakamoto T, Shiomi T, Okada Y, Itoh T, Itohara S, Seiki M, Yana I
- Journal Title
  
  Cancer Res. 67
  
  Pages: 4311-4319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Foxl1-deficient mice exhibit aberrant epithelial cell positioning due to dysregulated EphB/EphrinB expression in the small intestine.2006
- Author(s)
  Takano-Maruyama M, Hase K, Fukamachi H, Kato Y, Koseki H, Ohno H
- Journal Title
  
  Amer J Physiol Gastrointest Liver Physiol 291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Runx3 controls growth and differentiation of gastric epithelial cells in mammals2006
- Author(s)
  Fukamachi, H
- Journal Title
  
  Develop. Growth Differ. 48
  
  Pages: 1-13
- NAID
  10020141650
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Runx3 controls growth and differentiation of gastric epithelial cells in mammals2006
- Author(s)
  Fukamachi, H.
- Journal Title
  
  Develop.Growth Differ. 48
  
  Pages: 1-13
- NAID
  10020141650
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Runx3 controls growth and differentiation of gastric epithelial cells in mammals.2006
- Author(s)
  Fukamachi, H.
- Journal Title
  
  Develop.Growth Differ. 48
  
  Pages: 1-13
- NAID
  10020141650
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor s-induced apoptosis.2006
- Author(s)
  Yano T, Ito K, Fukamachi H, Chi X-Z, Wee H-J, Inoue K, Ida H, Bouillet P, Strasser A, Bae S-C, Ito Y
- Journal Title
  
  Mol Cell Biol 26
  
  Pages: 4474-4488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Runx3 controls growth and differentiation of gastric epithelial cells in mammals.2006
- Author(s)
  Fukamachi H
- Journal Title
  
  Develop Growth Differ 48
  
  Pages: 1-13
- NAID
  10020141650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Endothelin-3 controls growth of colonic epithelial cells by mediating epithelial-mesenchymal interaction2005
- Author(s)
  Fukamachi, H., et al.
- Journal Title
  
  Develop. Growth Differ. 47
  
  Pages: 572-580
- NAID
  10016891114
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Endothelin-3 controls growth of colonic epithelial cells by mediating epithelial-mesenchymal interaction.2005
- Author(s)
  Fukamachi H, Narita T, Yahagi N, Takeda H, Ichinose M.
- Journal Title
  
  Develop. Growth Differ. 47
  
  Pages: 572-580
- NAID
  10016891114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Endothelin-3 controls growth of colonic epithelial cells by mediating epithelial-mesenchymal interaction2005
- Author(s)
  Fukamachi, H., et al.
- Journal Title
  
  Develop.Growth Differ. 47
  
  Pages: 572-580
- NAID
  10016891114
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Endothelin-3 controls growth of colonic epithelial cells by mediating epithelial-mesenchymal interaction.2005
- Author(s)
  Fukamachi, H., et al.
- Journal Title
  
  Develop.Growth Differ. 47
  
  Pages: 572-580
- NAID
  10016891114
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Transforming growth factor- β-dependent sequential activation of Smads, Bim and caspase-9 mediates physiological apoptosis in gastric epithelial cells.2005
- Author(s)
  Ohsugi M, Kuroki K, Fukamachi H, O'Reilly LA, Kuida K, Strasser A, Yonehara, S.
- Journal Title
  
  Mol. Cell. Biol. 25
  
  Pages: 10017-10028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Runx3-/- gastric epithelial cells differentiate into intestinal type cells2004
- Author(s)
  Fukamachi, H., Ito, K., Ito, Y.
- Journal Title
  
  Biochem, Biophys.Res.Commun. 321
  
  Pages: 58-64
- Data Source
  KAKENHI-PROJECT-16021212
[Journal Article] Reduced expression of SNAP25 and H^+,K^+-ATPase with acid secretion defect in gastric parietal cells of Foxl1^<-/-> mice.2004
- Author(s)
  Kato, Y., Fukamachi, H., et al.
- Journal Title
  
  Biochem, Biophys.Res.Commun. 320
  
  Pages: 766-772
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Runx3-/- gastric epithelial cells differentiate into intestinal type cells2004
- Author(s)
  Fukamachi, H., Ito, K., Ito, Y.
- Journal Title
  
  Biochem, Biophys.Res.Commun. 321
  
  Pages: 58-64
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Growth regulation of gastric epithelial cells by Runx3.2004
- Author(s)
  Fukamachi.H., K.Ito.
- Journal Title
  
  Oncogene 23
  
  Pages: 4330-4335
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Runx3-/- gastric epithelial cells differentiate into intestinal type cells.2004
- Author(s)
  Fukamachi.H., et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 321
  
  Pages: 58-64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Reduced expression of SNAP25 and H^+,K^+-ATPase with acid secretion defect in gastric parietal cells of Foxll^<-/-> mice.2004
- Author(s)
  Kato, Y., Fukamachi, H., et al.
- Journal Title
  
  Biochem, Biophys.Res.Commun. 320
  
  Pages: 766-772
- Data Source
  KAKENHI-PROJECT-16021212
[Journal Article] Growth regulation of gastric epithelial cells by Runx3.2004
- Author(s)
  Fukamachi, H., K.Ito
- Journal Title
  
  Oncogene 23
  
  Pages: 4330-4335
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Runx3-/- gastric epithelial cells differentiate into intestinal type cells2004
- Author(s)
  Fukamachi, H., et al.
- Journal Title
  
  Biochem, Biophys. Res. Commun. 321
  
  Pages: 58-64
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Growth regulation of gastric epithelial cells by Runx3.2004
- Author(s)
  Fukamachi, H., K. Ito
- Journal Title
  
  Oncogene 23
  
  Pages: 4330-4335
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570049
[Journal Article] Growth regulation of gastric epithelial cells by Runx3.2004
- Author(s)
  Fukamachi.H., K.Ito
- Journal Title
  
  Oncogene 23
  
  Pages: 4330-4335
- Data Source
  KAKENHI-PROJECT-16021212
[Journal Article] miR-212 is downregulated and suppresses methyl-CpG-binding protein MeCP2 in human gastric cancer.
- Author(s)
  Wada R, Akiyama Y, Hashimoto Y, Fukamachi H, Yuasa Y
- Journal Title
  
  Int. J. Cancer (in press.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Diffuse-type gastric cancers are classified into two clusters, which may be formed via different carcinogenic pathways.2018
- Author(s)
  Fukamachi, H., Kim, S.-K., Koh, J., Lee, H. S., Nishikawaji T., Shimada, S., Akiyama, Y., Kim, Y. S., Kim, W. H., Yuasa, Y., Tanaka, S.
- Organizer
  INTERNATIONAL SYMPOSIUM Post-A3 Meeting 2018 Epigenetic Regulation of Cellular Stress Response
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] Diffuse-type gastric cancers are classified into two clusters, which may be formed via different carcinogenic pathways.2018
- Author(s)
  Fukamachi, H., Nishikawaji, T., Shimada, S., Akiyama, Y., Yuasa, Y., Tsuchiya, K., Tanaka, S.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] Identification of a signal transduction pathway working in the genesis and progression of diffuse type gastric cancers.2017
- Author(s)
  Fukamachi, H., Nishikawaji, T., Shimada, S., Akiyama, Y., Yuasa, Y., Tsuchiya, Kim, W. H., K., Tanaka, S.
- Organizer
  Post-A3 Meeting 2017 Epigenetic Signature of Carcinogenesis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] Identification of signal transduction pathway in PDX-derived diffuse-type gastric tumor-initiating cells.2017
- Author(s)
  Fukamachi, H., Nishikawaji, T., Shimada, S., Akiyama, Y., Yuasa, Y., Tsuchiya, K., Tanaka, S.
- Organizer
  The 76th Annual Meeting of the Japanese Cancer Association.
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] シンポジウム：臨床検体のゲノム解析に基づいた遺伝子改変およびゲノム編集技術の臨床応用2016
- Author(s)
  田中真二、島田周、古山貴基、大庭篤志、茂櫛薫、秋山好光、水野裕貴、小川康介、深町博史、伊藤浩光、光法雄介、松村聡、藍原有弘、伴大輔、落合高徳、工藤篤、川口義弥、田邉稔
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪（大阪府、大阪市）
- Data Source
  KAKENHI-PROJECT-16H02670
[Presentation] Identification of MTDs that suppress the growth of PDX-derived diffuse-type gastric tumor-initiating cells.2016
- Author(s)
  Fukamachi, H., Nishikawaji, T., Shimada, S., Akiyama, Y., Yuasa, Y., Tsuchiya, K., Tanaka, S.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] Characteristics of diffuse-type gastric cancer stem cells.2016
- Author(s)
  Fukamachi, H., Nishikawaji, T., Shimada, S., Akiyama, Y., Yuasa, Y., Tsuchiya, K., Tanaka, S
- Organizer
  26th Seoul Int. Cancer Symp. - Epigenetic Signature of Carcinogenesis
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-06-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] Identification of selective inhibitors of diffuse-type gastric cancer cells by screening of annotated compounds.2016
- Author(s)
  Shimada S, Akiyama Y, Fukamachi H, Yuasa Y, Tanaka S.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] Identification of selective inhibitors of diffuse-type gastric cancer cells by screening of annotated compounds.2015
- Author(s)
  Shimada S, Akiyama Y, Fukamachi H, Yuasa Y, Tanaka S.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] Features of poorly-differentiated gastric tumor-initiating cells from patient-derived tumor xenograft tissues.2015
- Author(s)
  Fukamachi, H., Shimada, S., Akiyama, Y., Yuasa, Y., Tsuchiya, K., Tanaka, S.
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06832
[Presentation] Synergistic tumor suppressor activity of E-cadherin and p53 in a conditional mouse model for diffuse-type gastric cancer2011
- Author(s)
  Shimada, S., Mimata, A., Mogushi, K., Akiyama, Y., Fukamachi, H., Tanaka, H., Eishi, Y., Yuasa, Y.
- Organizer
  10th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Japanese Foundation for Cancer Research, Tokyo, Japan
- Year and Date
  2011-02-14
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification of tumor-initiating cells in human gastric cancers2011
- Author(s)
  Fukamachi, H., Seol, H. S., Shimada, S., Jang, S. J., Yuasa, Y.
- Organizer
  10th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Japanese Foundation for Cancer Research, Tokyo, Japan
- Year and Date
  2011-02-14
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification and characterization of human gastric tumor-initiating cells2011
- Author(s)
  Fukamachi, H., Shimada, S., Yuasa, Y.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Synergistic tumor suppressor activity of E-cadherin and p53 in a conditional mouse model for diffuse-type gastric cancer2011
- Author(s)
  Shimada, S., Mimata, A., Akiyama, Y., Fukamachi, H., Yuasa Y.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Runx3 protects gastric cepithelial cells against EMT and Lgr5-expressing tumorigenic subpopulation2011
- Author(s)
  Ito, Y., Ito, K., Fukamachi, H.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Runx3 protects gastric cepithelial cells against EMT and Lgr5-expressing tumorigenic subpopulation2011
- Author(s)
  Ito, Y., Ito, K., Fukamachi, H.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Epigenetic changes in gastric cancer stem cells2011
- Author(s)
  Fukamachi, H.
- Organizer
  NSFC A3 Foresight Program 2011 Workshop-Epigenetic Signatures in Gastric Carcinogenesis
- Place of Presentation
  Xi' an, China
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification and characterization of human gastric tumor-initiating cells2011
- Author(s)
  Fukamachi, H., Shimada, S., Yuasa, Y.
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification of tumor-initiating cells in human gastric cancers2011
- Author(s)
  Fukamachi, H., et al
- Organizer
  IGCC 2011-9^<th> Int.Gastric Cancer Congress
- Place of Presentation
  Coex Center, Seoul, Korea
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Epigenetic changes in gastric cancer stem cells2011
- Author(s)
  Fukamachi, H.
- Organizer
  NSFC A3 Foresight Program 2011 Workshop- Epigenetic Signatures in Gastric Carcinogenesis
- Place of Presentation
  Xijing Hospital, Xi'an, China
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Mouse model of diffuse-type gastric cancer by conditional inactivation of E-cadherin and p532011
- Author(s)
  Shimada, S., Mimata, A., Mogushi, K., Akiyama, Y., Fukamachi, H., Jonkers, J., Tanaka, H., Eishi, Y., Yuasa, Y.
- Organizer
  IGCC 2011-9th International Gastric Cancer Congress
- Place of Presentation
  Coex Center, Seoul, Korea
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification of tumor-initiating cells in human gastric cancers2011
- Author(s)
  Fukamachi, H., Seol, H., Shimada, S., Jang, S., Yuasa, Y.
- Organizer
  IGCC 2011-9th International Gastric Cancer Congress
- Place of Presentation
  Coex Center, Seoul, Korea
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification and characterization of human gastric tumor-initiating cells2011
- Author(s)
  Fukamachi, H.
- Organizer
  Seoul Pathology Forum
- Place of Presentation
  Seoul National University Hospital, Seoul, Korea
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification of tumor-initiating cells in human gastric cancers2010
- Author(s)
  Fukamachi, H., Shimada, S., Seol, H. S., Jang, S. J., Yuasa, Y.
- Organizer
  NSFC A3 Foresight Program 2010 Seminar : Epigenetic Signatures in Gastric Carcinogenesis
- Place of Presentation
  Beijing, China
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification of tumor-initiating cells in human gastric cancers2010
- Author(s)
  Fukamachi, H., Shimada, S., Seol, H. S., Funasaka, C., Jang, S. J., Yuasa, Y.
- Organizer
  The 5th Asian Epigenomics Meeting & A3 Symposium 2010
- Place of Presentation
  Jeju、Korea
- Year and Date
  2010-06-21
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Loss of E-cadherin in parietal cells affects gastric epithelial cell polarity, growth and differentiation, resulting in a pre-malignant condition in mice2010
- Author(s)
  Mimata, A., Fukamachi, H., Eishi, Y., Yuasa, Y.
- Organizer
  NSFC A3 Foresight Program 2010 Seminar : Epigenetic Signatures in Gastric Carcinogenesis
- Place of Presentation
  Beijing, China
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification of tumor-initiating cells in human gastric cancers2010
- Author(s)
  Fukamachi, H., Shimada, S., Yuasa, Y.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Invasive diffuse gastric cancers develop in E-cadherin/p53 conditional double knockout mice2010
- Author(s)
  Shimada, S., Mimata, A., Akiyama, Y., Fukamachi, H., Yuasa Y.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Synergistic tumor suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer2010
- Author(s)
  Shimada, S. Mimata, A., Akiyama, Y., Fukamachi, H., Eishi, Y., Yuasa, Y.
- Organizer
  NSFC A3 Foresight Program 2010 Seminar : Epigenetic Signatures in Gastric Carcinogenesis
- Place of Presentation
  Beijing, China
- Year and Date
  2010-10-18
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Precancerous changes are induced in E-cadherin KO mouse stomachs2010
- Author(s)
  Mimata, A., Fukamachi, H., Yuasa, Y.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification of tumor-initiating cells in human gastric cancers.2010
- Author(s)
  Fukamachi.H., et al.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] RUNX3(R122C) does not attenuate oncogenic Wnt in gastric epithelial cells2010
- Author(s)
  Ito, K., Fukamachi, H., Ito, Y.
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22501005
[Presentation] Identification of tumor-initiating cells in the human gastric cancer2009
- Author(s)
  Fukamachi, H, 他
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Identification of cancer stem cells in human gastric cancers2009
- Author(s)
  Fukamachi, H., Yuasa, Y.
- Organizer
  JSPS A3 Foresight Program. 2009 First Meeting Epigenetic Signatures in Gastric Carcinogenesis
- Place of Presentation
  東京
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] 胃がん細胞におけるIQGAP2遺伝子のメチル化によるサイレンシングと浸潤能の亢進2008
- Author(s)
  湯浅保仁、金順花、深町博史、秋山好光
- Organizer
  第9回日本がん分子疫学研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Loss of Runx3 affects ovulation and estrogen-induced endometrial cell proliferation in female mice.2008
- Author(s)
  Takahashi, S., Sakuma, A., Fukamachi, H., Ito, K., Ito, Y., S. Takeuchi, S.
- Organizer
  The Endocrine Society, 90th Annual Meeting, Program & Abstracts
- Place of Presentation
  San Francisco
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-19370025
[Presentation] Runx3-/-p53-/-胃がん細胞株の幹細胞の同定2008
- Author(s)
  深町博史, 他
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Identification of stem-like cells in Runx3-/-p53-/-gastric Cancer cell lines2008
- Author(s)
  Fukamachi, H., & Yuasa, Y.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17012017
[Presentation] Runx3-/- gastric epithelial cells differentiate into intestinal type cells in vitro2007
- Author(s)
  Fukamachi H, Tanaka I, Ito K, Ito Y, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Researc
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Identification of stem-like cells from p53-/- gastro-intestinal epithelial cell lines by FACS2007
- Author(s)
  深町博史、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Expression analysis of microRNA in gastric cancer2007
- Author(s)
  和田りえ、秋山好光、深町博史、湯浅保仁
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Differentiation of Runx3-/-p53-/- gastric epithelial cells into intestinal type cells in vitro2007
- Author(s)
  Fukamachi H, Tanaka I, Ito K, Ito Y, Yuasa Y
- Organizer
  Int. RUNX Meeting
- Place of Presentation
  Singapore
- Year and Date
  2007-08-20
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] p53-/- 消化管上皮細胞株内の幹様細胞の同定とその性質2007
- Author(s)
  深町博史、湯浅保仁
- Organizer
  日本動物学会第78回大会
- Place of Presentation
  弘前
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] IQGAP2 inactivation through aberrant promoter methylation and promotion of invasion in gastric cancer cells2007
- Author(s)
  Jin S-H, Akiyama Y, Fukamachi H, Yanagihara K, Akashi T, Yuasa Y
- Organizer
  The 8th Korea-Japan Joint Symposium on Cancer and Ageing Researc
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-17015013
[Presentation] Differentiation of Runx3-/-p53-/-gastric epithelial cells into intestinal type cells in vitro2007
- Author(s)
  Fukamachi, H., et. al.
- Organizer
  14th RUNX Meeting
- Place of Presentation
  Breakthrough & Discovery Theatrettes, Biopolis, Singapore,
- Year and Date
  2007-08-20
- Data Source
  KAKENHI-PROJECT-17012017

1. TAKIZAWA Touichiro (80323674)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. SUGIHARA Kenichi (10171167)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. AKIYAMA Yosimitsu (80262187)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. IMAI Kazue (80260230)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAKEUCHI Sakae (20226989)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
6. YUASA Yasuhito (80111558)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
7. KAWANO Tatsuyuki (00186115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TAKAHASHI Sumio (90144807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. YAMAMURA Kenichi (90115197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMADA Gen (80174712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ARAKI Kimi (90211705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ITOH Toshio (20106644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KATOH Hideki (30142053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKAGATA Naomi (30159058)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKO Kazuki (20217657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. OBATA Yuichi (30177290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YAMAZAKI Yukiko (00239956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MATSUI Yasuhisa (40241575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. WANIBUCHI Hideki (90220970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MITSUMORI Kunitoshi (10239296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. USHIJIMA Toshikazu (90232818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. OGAWA Katsuhiro (50045514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. TATEMATSU Masae (70117836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. TANAKA Shinji (30253420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
25. 岩井武尚 (90111591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 江石義信 (70151959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 三宅智 (00332346)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 大倉康男 (30312284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 熊谷二朗 (80280973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 矢作直久 (90292937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 森正樹 (70190999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 島田周 (20609705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
33. SAKUMA Atsuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. TSUCHIYA Yukiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
35. SAITO Yuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
36. OGO Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
37. OJIMA Fumiya

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
38. HAYASHI Sayo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. KAYO Daichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
40. MAEKAWA Tetsuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. GU TinTin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 時野隆至

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUKAMACHI Hiroshi 深町 博史

深町 博史 フカマチ ヒロシ

Research Projects

Research Products

Co-Researchers

Develoment of advanced therapy targeting tumor heterogeneity in refractory cancers

Principal Investigator

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Mechanism how scirrhous-type gastric cancer is formedPrincipal Investigator

Principal Investigator

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Roles of transcription factor Runx 3 in ovarian follicle development and ovulation in mice

Principal Investigator

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Identification and characterization of human gastric cancer stem cellsPrincipal Investigator

Principal Investigator

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Regulatory mechanism of breakdown and reconstruction of reproductive organs

Principal Investigator

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Integrated cancer research using in vivo models

Principal Investigator

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Relationship between surrogate markers including DNA methylation and lifestyle factors in gastric carcinogenesis

Principal Investigator

Project Period (FY)

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Research Institution

Runx3欠失胃上皮細胞を用いた胃がんおよび腸上皮化生形成機構の解析Principal Investigator

Principal Investigator

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Role of Runx3 on the regulation of growth and differentiation and intestinal metaplasia of gastric epithelial cellsPrincipal Investigator

Principal Investigator

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胃がん抑制遺伝子Runx3の作用機構の解析Principal Investigator

Principal Investigator

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Review Section

Research Institution

mecanism of Diffrentiation and Evolution of Parietal and Chief Cells in Vertebrate StomachsPrincipal Investigator

Principal Investigator

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宿主・環境要因に着目した消化管がんの二次原発がん発生リスクに関する研究

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Molecular Mechanism of Epithelial-Mesenchymal InteractionsPrincipal Investigator

Principal Investigator

Project Period (FY)

FUKAMACHI Hiroshi 深町博史

深町博史フカマチヒロシ