TOMINAGA Shinichi 富永眞一

… Alternative Names

富永眞一トミナガシンイチ

TOMINAGA Shin-ichi 富永眞一

富永真一トミナガシンイチ

TOMINAGA S 富永慎一

Less

Researcher Number	70155571
Other IDs
External Links
Affiliation (Current)	2025: 自治医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2007 – 2015: Jichi Medical University, 医学部, 教授 2001 – 2003: 自治医科大学, 医学部, 教授 1995: 自治医科大学, 医学部, 助教授 1990 – 1992: 自治医科大学, 医学部, 助教授 1988 – 1989: 冲中記念成人病研究所, 主任研究員
Review Section/Research Field	Principal Investigator Pathological medical chemistry Except Principal Investigator Digestive surgery / Respiratory organ internal medicine / Neurology / Hematology
Keywords	Principal Investigator 細胞増殖 / シグナル伝達 / ST2遺伝子 / 細胞間相互作用 / ST2 / IL-33 / 免疫学 / タンパク質 / リガンド / 分泌タンパク質 … More / G_1移行期 / G_0 / 細胞周期 / インタ-ロイキン1受容体 / イミュノグロブリンス-パ-ファミリ- / 抗がん作用 / NIH-3T3 / ST2L / 分泌 / NIH-3T3 cells / 線維芽細胞 / アレルギー疾患 / 糖鎖 / アレルギー・ぜんそく / 抗炎症作用 / 糖鎖修飾 / ミエローマ細胞 / ヘルパーT細胞 / インターロイキン1受容体 / サイトカイン … More Except Principal Investigator ST2 / Th2 / 血小板輸血 / 抗血小板抗体 / 血小板型 / スカベンジャー / エチオニン / エンドトキシン / ライソゾーム / 膵酵素逸脱 / cholecysokinin(CCK) / SOD / ライソゾーム酵素 / 膵酵素 / エチオニン膵炎 / セルレイン膵炎 / 活性酸素 / プロスタグランディン / カテプシンD / カテプシンB / ライソゾ-ム酵素 / 急性膵炎 / 新生児血小板減少性紫斑病 / Allegic inflammation / Bronchial asthma / アレルギー性炎症 / 気管支喘息 / degeneration / neuronal hybridoma / cell fusion / cerebellum / 神経細胞株 / 小脳変性症 / 神経ハイブリドーマ細胞株 / 細胞融合 / 小脳 / 母児血小板型不適合 / 新生児血小板減少性性紫斑病 / 輸血後紫斑病 / 混合受身凝集法 / 新生児血小板減少性紫性班病 Less

Study on the mechanism of cell growth regulation by ST2 and its possible anti-cancerous effect.Principal Investigator
- Principal Investigator
  
  Tominaga Shin-ichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Jichi Medical University
The implication of conformational change of ST2 gene product due to polymorphism for various diseases.Principal Investigator
- Principal Investigator
  
  TOMINAGA Shinichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Jichi Medical University
Identification of functional regions the soluble ST2 protein against inflammation, and its possible application for novel drugs.Principal Investigator
- Principal Investigator
  
  TOMINAGA Shinichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Jichi Medical University
Bronchila asthma and new Th2 type gene-ST2
- Principal Investigator
  
  SUGIYAMA Yukihiko
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Jichi Medical School
ヒトがん細胞で発現している受容体型ST2の生物学的機能Principal Investigator
- Principal Investigator
  
  富永真一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
細胞増殖開始過程で特異的に発現されるST2遺伝子産物の生物学的機能Principal Investigator
- Principal Investigator
  
  富永眞一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
Establishment of cerebellar Purkinje cell lines by somatic cell fusion
- Principal Investigator
  
  NISHIZAWA Masatoyo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Jichi Medical School
細胞増殖開始過程で特異的に発現されるST2遺伝子産物の生物学的機能Principal Investigator
- Principal Investigator
  
  富永眞一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Jichi Medical University
新しい血小板型抗原YuK^a,YuK^bに関する臨床的研究
- Principal Investigator
  
  柴田洋一
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Okinaka Memorial Institute for Medical Research
新しい血小板型抗原YuK^a、YuK^bに関する臨床的研究
- Principal Investigator
  
  柴田洋一, 真辺忠夫
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] IL-33の基礎とアレルギー性炎症の誘導炎症と免疫2010
- Author(s)
  早川盛禎、富永眞一
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-22590289
[Journal Article] Soluble form of the ST2 gene product exhibits growth promoting activity in NIH-3T3 cells2016
- Author(s)
  Tominaga S-I, Ohta S, Tago K.
- Journal Title
  
  Biochem Biophys Rep
  
  Volume: 5 Pages: 8-15
- DOI
  10.1016/j.bbrep.2015.11.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-25460393
[Journal Article] Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells2016
- Author(s)
  Hiroko Hayakawa, Morisada Hayakawa, Shin-ichi Tominaga
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 5 Pages: 401-407
- DOI
  10.1016/j.bbrep.2016.02.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670161, KAKENHI-PROJECT-25460393
[Journal Article] IL-33受容体ST2Lと分泌型ST22015
- Author(s)
  富永眞一
- Journal Title
  
  医学のあゆみ
  
  Volume: 252 Pages: 1193-1196
- Data Source
  KAKENHI-PROJECT-25460393
[Journal Article] Dual function of IL-33 on proliferation of NIH 3T3 cells2015
- Author(s)
  Tominaga S., Tago K., Tsuda H., Komine M.
- Journal Title
  
  Cytokine
  
  Volume: 72 Issue: 1 Pages: 105-108
- DOI
  10.1016/j.cyto.2014.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461709, KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-25460393
[Journal Article] Presence of a novel exon 2E encoding a putative transmembrane protein in human IL-33 gene2013
- Author(s)
  Tominaga, S., Hayakawa, M., Tsuda, H., Ohta, S., and Yanagisawa, K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 430 Issue: 3 Pages: 969-974
- DOI
  10.1016/j.bbrc.2012.12.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289
[Journal Article] Soluble ST2 protein inhibits LPS stimulation on monocyte-derived dendritic cells2012
- Author(s)
  Nagata, A., Takezako, N., Tamemoto, H., Ohto-Ozaki, H., Ohta, S., Tominaga, S., and Yanagisawa, K.
- Journal Title
  
  Cell. Mol. Immunol
  
  Volume: 9 Issue: 5 Pages: 399-409
- DOI
  10.1038/cmi.2012.29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289
[Journal Article] Regulation of IL-33 expression by IFN-γ and tumor necrosis factor-α in normal human epidermal keratinocytes.2012
- Author(s)
  Meephansan, J., Tsuda, H., Komine, M., Tominaga, S., and Ohtsuki, M
- Journal Title
  
  J. Invest. Dermatol
  
  Volume: 132 Issue: 11 Pages: 2593-2600
- DOI
  10.1038/jid.2012.185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289, KAKENHI-PROJECT-23591652
[Journal Article] Sustained elevation of interleukin-33 in sera and synovial fluids from patients with rheumatoid arthritis non-responsive to anti-tumor necrosis factor: possible association with persistent IL-1βsignaling and a poor clinical response2012
- Author(s)
  Matsuyama, Y., Okazaki, H., Hoshino, M., Onishi, S., Kamata, Y., Nagatani, K., Nagashima, T., Iwamoto, M., Yoshio, T., Ohto-Ozaki, H., Tamemoto, H., Komine, M.,Sekiya, H., Tominaga, S. and Minota, S.
- Journal Title
  
  Rheumatol. Int
  
  Volume: 32 Issue: 5 Pages: 1397-1401
- DOI
  10.1007/s00296-011-1854-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289
[Journal Article] Ultraviolet B irradiation induces the expression of IL-33 mRNA and protein in normal human epidermal keratinocytes2012
- Author(s)
  Meephansan, J., Komine, M., Tsuda, H., Tominaga, S., and Ohtsuki, M.
- Journal Title
  
  J. Dermatol. Sci
  
  Volume: 65 Issue: 1 Pages: 72-74
- DOI
  10.1016/j.jdermsci.2011.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289
[Journal Article] The levels of soluble ST2 in sera and bullous fluid from patients with bullous pemphigoid.2012
- Author(s)
  Wakatabi, K., Komine, M., Meephansan, J., Matsuyama, Y., Tsuda, H., Tominaga, S., and Ohtsuki, M.
- Journal Title
  
  Eur. J. Dermatol
  
  Volume: 22 Issue: 3 Pages: 333-336
- DOI
  10.1684/ejd.2012.1706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289, KAKENHI-PROJECT-23591652
[Journal Article] YM-175 induces apoptosis of human native monocyte-lineage cells via inhibition of prenylation.2012
- Author(s)
  Miwa, A., Takezako, N., Hayakawa, H., Hayakawa, M., Tominaga, S., and Yanagisawa, K.
- Journal Title
  
  Am. J. Hematol
  
  Volume: 87 Issue: 12 Pages: 1084-1088
- DOI
  10.1002/ajh.23328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289
[Journal Article] Novel splice variants of IL-33: Differential expression in normal and transformed cells2012
- Author(s)
  Tsuda, H., Komine, M., Karakawa, M., Etoh, T., Tominaga, S., and Ohtsuki, M
- Journal Title
  
  J. Invest. Dermatol
  
  Volume: 132 Issue: 11 Pages: 2661-2664
- DOI
  10.1038/jid.2012.180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289, KAKENHI-PROJECT-23591652
[Journal Article] JAK2 is an important signal transducer in IL-33-induced NF-κB activation.2011
- Author(s)
  Funakoshi-Tago, M., Tago, K., Sato, Y., Tominaga, S., and Kasahara, T.
- Journal Title
  
  Cell. Signal
  
  Volume: 23 Issue: 2 Pages: 363-370
- DOI
  10.1016/j.cellsig.2010.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289, KAKENHI-PROJECT-23570166, KAKENHI-PROJECT-23790096
[Journal Article] ST2 gene expression is proliferation-dependent and its ligand, IL-33, induces inflammatory reaction in endothelial cells2010
- Author(s)
  Aoki, S., Hayakawa, M., Ozaki, H., Takezako, N., Obata, H., Ibaraki, N., Tsuru, T., Tominaga, S., Yanagisawa, K.
- Journal Title
  
  Mol. Cell. Biochem. 335
  
  Pages: 75-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590318
[Journal Article] Increased levels of interleukin-33 in sera and synovial fluids from patients with active rheumatoid arthritis2010
- Author(s)
  Matsuyama, Y., Okazaki, H., Tamemoto, H., Kimura, H., Kamata, Y., Nagatani, K., Nagashima, T., Hayakawa, M., Iwamoto, M., Yoshio, T., Tominaga, S., Minota, S.
- Journal Title
  
  J. Rheumatol. 37
  
  Pages: 18-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590318
[Journal Article] IL-33の基礎とアレルギー性炎症の誘導2010
- Author(s)
  富永真一
- Journal Title
  
  炎症と免疫
  
  Volume: VOL.18 Pages: 15-20
- Data Source
  KAKENHI-PROJECT-22590289
[Journal Article] Characterization of ST2 transgenic mice with resistance to IL-33.2010
- Author(s)
  Ohto-Ozaki, H., Kuroiwa, K., Mato, N., Matsuyama, Y., Hayakawa, M., Tamemoto, H., and Tominaga, S.
- Journal Title
  
  Eur. J. Immunol
  
  Volume: 40 Issue: 9 Pages: 2632-2642
- DOI
  10.1002/eji.200940291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590289
[Journal Article] IL-1R-related protein ST2 suppressed the initial stage of bleomycin-induced lung injury2009
- Author(s)
  Mato, N., Fujii, M., Hakamata, Y., Kobayashi, E., Sato, A., Hayakawa, M., Ohto-Ozaki, H., Bando, M., Ohno, S., Tominaga, S., Sugiyama, Y.
- Journal Title
  
  Eur. Respir. J. 33
  
  Pages: 1415-1428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590318
[Journal Article] Mature interleukin-33 is produced by calpain-mediated cleavage in vivo2009
- Author(s)
  Hayakawa, M., Hayakawa, H., Matsuyama, Y., Tamemoto, H., Okazaki, H., Tominaga, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 387
  
  Pages: 218-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590318
[Journal Article] TRAF6 is a critical signal transducer in IL-33 signaling pathway.2008
- Author(s)
  Funakoshi-Tago, M., Tago, K., Hayakawa, M., Tominaga, S., Ohshio, T., Sonoda, Y., Kasahara, T.
- Journal Title
  
  Cell. Signal. 20
  
  Pages: 1679-1686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590318
[Journal Article] ST2 gene induced by type 2 helper T cell (Th2) and proinflammatory cytokine stimuli may modulate lung injury and fibrosis2007
- Author(s)
  Tajima, S., Bando, M., Ohno, S., Sugiyama, Y., Oshikawa, K., Tominaga, S., Itoh, K., Takada, T., Suzuki, E., Gejyo, F.
- Journal Title
  
  Exp. Lung Res. 33
  
  Pages: 81-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590318
[Journal Article] Soluble ST2 blocks IL-33 signaling in allergic airway inflammation2007
- Author(s)
  Hayakawa, H., Hayakawa, M., Kume, A., Tominaga, S.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 26369-26380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] 分泌型ST2はアトピー性皮膚炎における皮膚炎症を軽減する。2015
- Author(s)
  早川盛禎、早川裕子、大森司、富永眞一
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会（BMB2015）
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25460393
[Presentation] ジシストロウイルスPSIV遺伝子間領域のRNA配列と終止コドンリードスルー。2015
- Author(s)
  鴨下信彦、富永眞一、中島信彦
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会（BMB2015）
- Place of Presentation
  神戸
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-25460393
[Presentation] IL-33は表皮角化細胞核内で細胞分裂に関与している。2015
- Author(s)
  津田英利、小宮根真弓、富永眞一、大槻マミ太郎
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会（BMB2015）
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460393
[Presentation] Effect of Soluble ST2 on Activation of Type 2 Innate Lymphoid Cells in a Murine Model of Asthma.2015
- Author(s)
  Hiroko Hayakawa, Morisada Hayakawa, Shin-ichi Tominaga
- Organizer
  30th Congress of the International Society for Advancement of Cytometry (Cyto 2015)
- Place of Presentation
  Glasgow, UK
- Year and Date
  2015-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460393
[Presentation] Interleukin-33はTGF-β/Smadシグナル伝達経路の活性化を抑制する。2014
- Author(s)
  早川盛禎、早川裕子、富永眞一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25460393
[Presentation] ケラチノサイトにおけるIL-33のノックダウンは細胞分裂を抑制する。2014
- Author(s)
  津田英利、小宮根真弓、大塩智之、富永眞一、大槻マミ太郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25460393
[Presentation] Soluble ST2 suppresses the effect of IL-33 on type 2 innate lymphoid cells.2014
- Author(s)
  Hiroko Hayakawa, Morisada Hayakawa, and Shin-ichi Tominaga
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25460393
[Presentation] Regulation of IL-33 expression by interferon-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.2012
- Author(s)
  Meephansan, J., Tsuda, H., Komine, M., Karakawa, M., Tominaga, S., Ohtsuki, M.
- Organizer
  Annual Meeting of the Society for Investigative Dermatology.
- Place of Presentation
  Raleigh, North Carolina, USA
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] ST2遺伝子の選択的スプライシングにおけるトランス因子の解析2012
- Author(s)
  鴨下信彦、為本浩至、早川盛禎、富永眞一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] IL-33は核内でケラチノサイトの細胞増殖に関与している。2012
- Author(s)
  Tsuda, H., Komine, M., Oshio, T., Tominaga, S., Ohtsuki, M.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] IL-33受容体ST2Lの細胞外ドメイン放出。2012
- Author(s)
  Tamemoto, H., Kamoshita, N., Kashiwada, M., Hayakawa, M., Ozaki, H., Tominaga, S.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Regulation of IL-33 expression by interferon-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.2012
- Author(s)
  Meephansan, J., Tsuda, H., Komine, M., Karakawa, M., Tominaga, S., Ohtsuki, M
- Organizer
  Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Raleigh, North Carolina, USA
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Soluble ST2 protein inhibits LPS stimulation on monocyte-derived dendritic cells2012
- Author(s)
  Nagata, A., Ohta, S., Tominaga, S.,Yanagisawa, K
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] IL-17 up regulates IL-33 expression in keratinocytes; negative feedback loop in psoriatic epidermis.2012
- Author(s)
  Meephansan, J., Tsuda, H., Komine, M., Karakawa, M., Tominaga, S., Ohtsuki, M.
- Organizer
  The 42nd Annual ESDR (European Society for Dermatological Research) Meeting.
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Shedding of receptor for IL-33 (ST2L)2012
- Author(s)
  Tamemoto, H., Kamoshita, N., Kashiwada, M., Hayakawa, M., Ozaki, H., Tominaga, S
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Nuclear IL-33 in relation to proliferation and cell cycle of normal human epidermal keratinocytes2012
- Author(s)
  Tsuda, H., Komine, M., Oshio, T., Tominaga, S., Ohtsuki, M
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] ヒト単球由来樹状細胞に対する分泌型ST2タンパク質の作用。2012
- Author(s)
  Nagata, A., Ohta, S., Tominaga, S., Yanagisawa, K.
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] ST2遺伝子の選択的スプライシングにおけるトランス因子の解析。2012
- Author(s)
  鴨下信彦、為本浩至、早川盛禎、富永眞一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] IL-17 up regulates IL-33 expression in keratinocytes; negative feedback loop in psoriatic epidermis2012
- Author(s)
  Meephansan, J., Tsuda, H., Komine, M., Karakawa, M., Tominaga, S., Ohtsuki, M
- Organizer
  The 42ndAnnual ESDR (European Society for Dermatological Research)Meeting
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] IL-33 is produced by normal human keratinocytes with environmental and inflammatory stimuli: A novel "alarmin" in the skin2011
- Author(s)
  Meephansan, J., Komine, M., Tsuda, H., Yano, S., Tominaga, S., Ohtsuki, M
- Organizer
  Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Phoenix, Arizona, USA
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Alternative splicing in ST2 gene.2011
- Author(s)
  Kamoshita, N., Tamemoto, H., Hayakawa, M., Tominaga, S
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Novel splicing variants of IL-33 and its expression variation2011
- Author(s)
  Tsuda, H., Meephansan, J., Karakawa, M., Tominaga, S., Komine, M., and Ohtsuki, M.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Localization of intracellular domain of ST2L.2011
- Author(s)
  Tamemoto, H., Hayakawa, M., Kamoshita, N., Ozaki, H., Tominaga, S.
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Sustained elevation of interleukin-33 in serum and synovial fluid is associated with a poor response of rheumatoid arthritis to anti-tumor necrosis factor therapy2010
- Author(s)
  Matsuyama, Y., Okazaki, H., Hoshino, T., Onishi, S., Ohto-Ozaki, H., Tamemoto, H., Tominaga, S., and Minota, S.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Soluble ST2 attenuated the IL-33-induced M2 polarization of peritoneal macrophages2010
- Author(s)
  Ohto-Ozaki, H., Kuroiwa, K., Matsuyama, Y., Hayakawa, M., Tamemoto, H., and Tominaga, S.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Environmental stimuli up regulate IL-33 in normal human keratinocytes.2010
- Author(s)
  Meephansan, J., Komine, M., Wakatabi, K., Tominaga, S., Ohtsuki, M.
- Organizer
  Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Atlanta, Georgia, USA
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] Ectodomain shedding of ST2L, a member of IL-1 receptor family.2010
- Author(s)
  Tamemoto, H., Ozaki, H., Kamoshita, N., Hayakawa, M., and Tominaga, S.
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22590289
[Presentation] IL-33 induces inflammatory reaction in endothelial cells, and its receptor, ST2L is expressed in growth-dependent manner. (IL-33は内皮細胞に炎症反応を惹起し, その受容体のST2Lは増殖依存性に内皮細胞に発現する. )2009
- Author(s)
  柳澤健, 太田聡, 松儀実広, 富永眞一
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] Increased levels of interleukin-33 in sera and synovial fluids from patients with active rheumatoid arthritis2009
- Author(s)
  松山泰, 岡崎仁昭, 為本浩至, 早川盛禎, 岩本雅弘, 富永眞一, 簑田清次
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] The immunological reactions induced by intraperitoneal administration of IL-33 were attenuated in ST2 transgenic mice. (ST2トランスジェニックマウスを用いた, ST2の抗IL-33効果の検討.)2009
- Author(s)
  尾崎裕美, 黒岩憲二, 早川盛禎, 為本浩至, 富永眞一
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] ST2遺伝子と病気2008
- Author(s)
  富永眞一, 早川裕子, 早川盛禎, 柳澤健
- Organizer
  3学会合同大会2008自然免疫の最前線第73回日本インターフェロン・サイトカイン学会学術集会/第19回日本生体防御学会学術集会/第45回補体シンポジウム3学会合同集会
- Place of Presentation
  札幌
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] ST2遺伝子と病気2008
- Author(s)
  富永眞一, 他
- Organizer
  第73回インターフェロン・サイトカイン学会学術集会, 第19回日本生体防御学会学術集会, 第45回補体シンポジウム3学会合同集会
- Place of Presentation
  札幌
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] ST2 works to suppress bleomycin induced lung injury2007
- Author(s)
  Mato, N., Bando, M., Ohno, S., Tominaga, S., Sugiyama, Y.
- Organizer
  2007 ATS International Conference in San Francisco
- Place of Presentation
  San Francisco, California
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] 分泌型ST2によるIL-33シグナル伝達系の抑制2007
- Author(s)
  早川裕子, 早川盛禎, 久米晃啓, 富永眞一
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] Incadronate can induce apoptosis in monocytic cells2007
- Author(s)
  Miwa, A., Takezako, N., Hayakawa, M., Yanagisawa, K., Tominaga, S.
- Organizer
  XIth International Myeloma Workshop and the IVth International Workshop on Waldenstrom's Macroglobulinemia
- Place of Presentation
  Kos Island, Greece
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] Dynamic subcellular localization of atypical small GTPase kappaB-Ras and its possible contribution to oncogenic signals2007
- Author(s)
  多胡憲治, 多胡めぐみ, 水野憲一, 笠原忠, 富永眞一, 伊東広
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] Soluble ST2 suppresses ST2L-based IL-33 signaling pathway2007
- Author(s)
  Hayakawa, M., Hayakawa, H., Kume, A., Kuroiwa, K., Hakamata, Y., Tominaga, S.
- Organizer
  15th Annual Meeting of the International Cytokine Society, Cytokines in Health and Disease
- Place of Presentation
  San Francisco, California
- Year and Date
  2007-10-27
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] 分泌型ST2タンパク質による単球系細胞の樹状細胞への分化抑制作用について2007
- Author(s)
  竹迫直樹, 早川裕子, 早川盛禎, 松儀実広, 柳澤健, 村尾捷利, 富永眞一
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19590318
[Presentation] IL-33シグナル伝達経路におけるTRAF6の役割の解析2007
- Author(s)
  多胡めぐみ, 多胡憲治, 早川盛禎, 富永眞一, 園田よし子, 笠原忠
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590318

1. YANAGISAWA Ken (50182366)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 柴田洋一 (30010474)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OHTA Satoshi (40528428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TAKEZAKO Naoki (80424026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. TAMEMOTO Hiroyuki (90292630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
6. KOMINE Mayumi (00282632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
7. HAYAKAWA Morisada (30326847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. TAGO KENJI (20306111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. NISHIZAWA Masatoyo (80198457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ARAKI M (00118449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OGAWA M (50194452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NIIJIMA K (80150613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SUGIYAMA Yukihiko (70183415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OSHIKAWA Katsuhisa (30326821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 真辺忠夫 (80127141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 馬場信雄 (10208712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 宮下正 (80182020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 井上一知 (90168435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 津田英利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 早川裕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TOMINAGA Shinichi 富永 眞一

富永 眞一 トミナガ シンイチ

TOMINAGA Shin-ichi 富永 眞一

富永 真一 トミナガ シンイチ

TOMINAGA S 富永 慎一

Research Projects

Research Products

Co-Researchers

Study on the mechanism of cell growth regulation by ST2 and its possible anti-cancerous effect.Principal Investigator

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The implication of conformational change of ST2 gene product due to polymorphism for various diseases.Principal Investigator

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Identification of functional regions the soluble ST2 protein against inflammation, and its possible application for novel drugs.Principal Investigator

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Bronchila asthma and new Th2 type gene-ST2

Principal Investigator

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ヒトがん細胞で発現している受容体型ST2の生物学的機能Principal Investigator

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細胞増殖開始過程で特異的に発現されるST2遺伝子産物の生物学的機能Principal Investigator

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Establishment of cerebellar Purkinje cell lines by somatic cell fusion

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細胞増殖開始過程で特異的に発現されるST2遺伝子産物の生物学的機能Principal Investigator

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新しい血小板型抗原YuK^a,YuK^bに関する臨床的研究

Principal Investigator

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新しい血小板型抗原YuK^a、YuK^bに関する臨床的研究

Principal Investigator

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[Book] IL-33の基礎とアレルギー性炎症の誘導 炎症と免疫2010

Author(s)

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Data Source

[Journal Article] Soluble form of the ST2 gene product exhibits growth promoting activity in NIH-3T3 cells2016

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Data Source

[Journal Article] Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IL-33受容体ST2Lと分泌型ST22015

TOMINAGA Shinichi 富永眞一

富永眞一トミナガシンイチ

TOMINAGA Shin-ichi 富永眞一

富永真一トミナガシンイチ

TOMINAGA S 富永慎一

[Book] IL-33の基礎とアレルギー性炎症の誘導炎症と免疫2010