TANABE Tsutomu 田邊勉

Researcher Number	70183069
Other IDs
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Affiliation (based on the past Project Information) *help	2019 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, 教授 2007 – 2010: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 教授 2008: Tokyo Medical and Dental University, 大学院医歯学総合研究科, 教授 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 教授 2003 – 2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 … More 2000 – 2001: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 1996 – 1999: 東京医科歯科大学, 医学部, 教授 1988 – 1991: 京都大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 51030:Pathophysiologic neuroscience-related / Neurochemistry/Neuropharmacology Except Principal Investigator Biological Sciences / Neurochemistry/Neuropharmacology / General pharmacology
Keywords	Principal Investigator SCA6 / P型Caチャネル / 神経変性疾患 / ノックインマウス / 脊髄小脳失調症6型 / カルシウムチャネル / ES細胞 / 遺伝子ノックアウトマウス / Ca^<2+>チャネル / アルツハイマー病 … More / Cav2.2チャネル / Cav1.2チャネル / 老化 / 神経炎症 / パーキンソン病 / ミクログリア / 電位依存性Caチャネル / knock-in mouse / Cav2 channel / polyglutamine disease / Ca current / Purkinje cell / P-type calcium channel / Spinocerebellar ataxia type 6 / EA2 / FHM / Ca_v2チャネル / ポリグルタミン病 / Ca電流 / プルキンエ細胞 / 分子センター / 細胞感覚 / 痛覚過敏 / アロディニア / 神経因性疼痛 / 触覚 / 分子センサー / 小脳スライス / 神経細胞 / 神経伝達物質 / キメラマウス … More Except Principal Investigator SCA6 / 脊髄小脳変性症 / プルキンエ細胞 / cDNA expression / Site-directed mutagenesis / Nicotinic acetylcholine receptor / 電位感受機構 / cDNA発現 / 部位特異的変異 / Ca^<2+>チャンネル / Na^+チャンネル / ニコチン性アセチルコリン受容体 / Caチャンネル / ノックインマウス / Excitation-contraction coupling / Ca^<2+> channel / Na^+ channel / 興奮収縮連関 / CACNA1A / ES細胞 / CAGリピート / 培養細胞 / 連鎖解析 / nonSCA6 / α1A-Caチャンネル / Muscarinic acetylcholine receptor / Ca^<2+> release channel / ムスカリン性アセチルコリン受容体サブタイプ / E-C coupling / パッチクランプ法 / K^+チャンネル / cGMP-gatedチャンネル / Ca^<2+> releaseチャンネル / グルタミン酸受容体 / 静位特異的変異 / ムスカリン性アセチルコリン受容体 / Ca^<2+>放出チャンネル / G-proteins / transmitter regulation / biogenic amines / CNS synapses / Ca channels / synaptic transmission / Caチャネル / G蛋白質 / 伝達調節 / 生体アミン / 中枢シナプス / Ca チャネル / シナプス伝達 / Voltage sensing mechanism / Ion selectivity / イオン選択性 / Tetrodotoxin / Voltage sensor / Patch-clamp / Calcium channel / Sodium channel / テトロドトキシン / パッチクランプ / ポリグルタミン / 電位依存性不活性化 / Purkinje細胞 / 皮質性小脳萎縮症 / 生命科学 / 機能解析 / 遺伝情報 / 遺伝子 / ゲノム / リバース薬理学 / 薬理学 / 創薬 / トランスジェニックマウス Less

老化に伴う脳内炎症反応遷延化の要因の同定および制御法の開発Principal Investigator
- Principal Investigator
  
  田邊勉
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Tokyo Medical and Dental University
Conversion of touch sensation to pain by the modal shift of sensor functionPrincipal Investigator
- Principal Investigator
  
  TANABE Tsutomu
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
脊髄小脳失調症6型の発症機構の解明および予防、治療法の検討Principal Investigator
- Principal Investigator
  
  田邊勉
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Pathogenic mechanism of calcium channelopathyPrincipal Investigator
- Principal Investigator
  
  TANABE Tsutomu
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical and Dental University
α1A-Caチャンネル遺伝子の変異による脳細胞変性の分子病態
- Principal Investigator
  
  水澤英洋
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
遺伝性皮質性小脳萎縮症SCA6の発症機序の解明
- Principal Investigator
  
  水澤英洋
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Medical and Dental University
α1A-Caチャンネル遺伝子の変異による脳細胞変性の分子病態
- Principal Investigator
  
  水澤英洋
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
遺伝性皮質性小脳萎縮症SCA6の発現機序の解明と非SCA6の原因遺伝子の同定
- Principal Investigator
  
  水澤英洋
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Medical and Dental University
リバース薬理学の展開
- Principal Investigator
  
  三品昌美
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo
遺伝性皮質性小脳萎縮症(SCA6と非SCA6)の発現機序の解明と原因遺伝子の同定
- Principal Investigator
  
  水澤英洋
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Medical and Dental University
カルシウムチャネル遺伝子欠損神経細胞を用いた伝達物質放出制御機構の解析Principal Investigator
- Principal Investigator
  
  田邊勉
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
Control of Ca channels mediating cortical synaptic transmission by transmitter-receptors and G-protein
- Principal Investigator
  
  MURAKOSHI Takayuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical and Dental University
カルシウムチャネル遺伝子欠損神経細胞を用いた伝達物質放出制御機構の解析Principal Investigator
- Principal Investigator
  
  田邊勉
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
Mutagenesis Studies on Ionic Channels
- Principal Investigator
  
  NUMA Shosaku
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University
Studies on the tertiary structure and operational mechanism of ionic channels
- Principal Investigator
  
  IMOTO Keiji, 沼正作
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kyoto University
Studies on the structure and function of neurotransmitter receptors and ionic channels
- Principal Investigator
  
  NUMA Shosaku
- Project Period (FY)
  1988 – 1991
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Kyoto University

All 2020 2019 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book Patent

[Book] Genetic Approaches to the Elucidation of Calcium Channel Functions In Vivo. In "Calcium channel Pharmacology"(S. McDonough ed)2004
- Author(s)
  Saegusa, H., Tanabe, T.
- Publisher
  Kluwer Academic/Plenum Publishers
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300121
[Journal Article] Knockdown of microglial Cav2.2 N‐type voltage‐dependent Ca 2+ channel ameliorates behavioral deficits in a mouse model of Parkinson’s disease2020
- Author(s)
  Saegusa Hironao、Li Xu、Wang Xinshuang、Kayakiri Midori、Tanabe Tsutomu
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Issue: 17 Pages: 2914-2922
- DOI
  10.1002/1873-3468.13853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07840
[Journal Article] Blockade of microglial Cav1.2 Ca2+ channel exacerbates the symptoms in a Parkinson’s disease model2019
- Author(s)
  Wang Xinshuang、Saegusa Hironao、Huntula Soontaraporn、Tanabe Tsutomu
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 9138-9138
- DOI
  10.1038/s41598-019-45681-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07840
[Journal Article] Involvement of N-type Ca2+ channel in microglial activation and its implications to aging-induced exaggerated cytokine response2019
- Author(s)
  Huntula Soontaraporn、Saegusa Hironao、Wang Xinshuang、Zong Shuqin、Tanabe Tsutomu
- Journal Title
  
  Cell Calcium
  
  Volume: 82 Pages: 102059-102059
- DOI
  10.1016/j.ceca.2019.102059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07840
[Journal Article] Upregulation of casein kinase 1 epsilon in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain.2009
- Author(s)
  Sakurai, E., Kurihara, T., Kouchi, K., Saegusa, H., Zong, S., Tanabe, T.
- Journal Title
  
  Molecular Pain 5
  
  Pages: 74-74
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Peripheral-type benzodiazepine receptor antagonist is effective in relieving neuropathic pain in mice2009
- Author(s)
  Kondo, D., Saegusa, H., Yabe, R., Takasaki, I., Kurihara, T., Zong, S., Tanabe, T.
- Journal Title
  
  J Pharmacol.Sci. 110
  
  Pages: 55-63
- NAID
  10025736602
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Upregulation of casein kinase 1 epsilon in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain2009
- Author(s)
  Sakurai, E., Kurihara, T., Kouchi, K., Saegusa, H., Zong, S., Tanabe, T.
- Journal Title
  
  Molecular Pain 5
  
  Pages: 74-74
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Peripheral-type benzodiazepine receptor antagonist is effective in relieving neuropathic pain in mice.2009
- Author(s)
  Kondo, D., Saegusa, H., Yabe, R., Takasaki, I., Kurihara, T., Zong, S., Tanabe, T.
- Journal Title
  
  J.Pharmacol.Sci. 110
  
  Pages: 55-63
- NAID
  10025736602
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Deficit of heat shock transcription factor 1-heat shock 70kDa protein 1A axis determines the cell death vulnerability in a model of spinocerebellar ataxia type 62009
- Author(s)
  Li, L., Saegusa, H., Tanabe, T.
- Journal Title
  
  Genes to Cells 14
  
  Pages: 1253-1269
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Deficit of heat shock transcription factor 1-heat shock 70kDa protein 1A axis determines the cell death vulnerability in a model of spinocerebellar ataxia type 6.2009
- Author(s)
  Li, L., Saegusa, H., Tanabe, T.
- Journal Title
  
  Genes to Cells 14
  
  Pages: 1253-1269
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Properties of human Cav2.1 channel with a spinocerebellar ataxia type 6 mutation expressed in Purkinje cells2007
- Author(s)
  Saegusa, H., Wakamori, M., Matsuda, Y., Wang, J., Mori, Y., Zong, S. and Tanabe, T
- Journal Title
  
  Mol. Cell. Neurosci 34
  
  Pages: 261-270
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Properties of human Cav2.1 channel with a spinocerebellar ataxia type 6 mutation expressed in Purkinje cells.2007
- Author(s)
  Saegusa, H., Wakamori, M., Matsuda, Y., Wang, J., Mori, Y., Zong, S., Tanabe, T.
- Journal Title
  
  Molec.Cell.Neurosci. 34
  
  Pages: 261-270
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Properties of human Ca_v2.1 channel with a spinocerebellar ataxia type 6 mutation expressed in Purkinje cells2007
- Author(s)
  Saegusa, H., Wakamori, M., Matsuda, Y., Wang, J., Mori, Y., Zong, S. and Tanabe, T.
- Journal Title
  
  Mol. Cell. Neurosci 34
  
  Pages: 261-270
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] 創薬ターゲットとしての電位依存性Ca^<2+>チャネル2007
- Author(s)
  田邊勉
- Journal Title
  
  医学のあゆみ 233
  
  Pages: 474-478
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Progesterone receptor antagonist is effective for relieving neuropathic pain2006
- Author(s)
  Kondo, D., Yabe, R., Kurihara, T., Saegusa, H., Zong, S. and Tanabe, T
- Journal Title
  
  Eur. J. Pharm 541
  
  Pages: 44-48
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Caチャネルと痛み伝達2006
- Author(s)
  田邊勉
- Journal Title
  
  日薬理誌 127
  
  Pages: 156-160
- NAID
  10019251744
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Progesterone receptor antagonist is effective for relieving neuropathic pain.2006
- Author(s)
  Kondo, D., Yabe, R., Kurihara, T., Saegusa, H., Zong, S., Tanabe, T.
- Journal Title
  
  Eur.J.Pharm. 541
  
  Pages: 44-48
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Altered cerebellar function in mice lacking Cav2.3 Ca^<2+> channel.2006
- Author(s)
  Osanai, M.., Saegusa, H., Kazuno, A., Nagayama, S., Hu, Q., Zong, S., Murakoshi, T., Tanabe, T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 344
  
  Pages: 920-925
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] カルシウムチャネル2006
- Author(s)
  田邊勉
- Journal Title
  
  Clinical Neuroscience 24
  
  Pages: 730-731
- Data Source
  KAKENHI-PLANNED-18077002
[Journal Article] Effects of glucocorticoid receptor antagonists on allodynia and hyperalgesia in mouse model of neuropathic pain2005
- Author(s)
  Takasaki, I., Kurihara, T., Saegusa, H., Zong, S., Tanabe, T
- Journal Title
  
  Eur.J.Pharm. 524
  
  Pages: 80-83
- Data Source
  KAKENHI-PROJECT-15300121
[Journal Article] The carboxy-terminal tail region of human Ca_v2.1 (P/Q-type) channel is not an essential determinant for its subcellular localization in cultured neurons2005
- Author(s)
  Hu, Q., Saegusa, H., Hayashi, Y., Tanabe, T.
- Journal Title
  
  Genes to Cells 10
  
  Pages: 87-96
- Data Source
  KAKENHI-PROJECT-15300121
[Journal Article] The carboxy-terminal tail region of human Ca_V2.1(P/Q-type) channel is not an essential determinant for its subcellular localization in cultured neurons2005
- Author(s)
  Hu, Q., Saegusa H., Hayashi, Y, Tanabe, T.
- Journal Title
  
  Genes to Cells 10
  
  Pages: 87-96
- Data Source
  KAKENHI-PROJECT-15300121
[Journal Article] Leukemia inhibitory factor activates cardiac L-type Ca^<2+> channels via phosphorylation of serine 1829 in the rabbit Ca_v1.2 subunit2004
- Author(s)
  Takahashi, E., Fukuda, K., Miyoshi, S., Murata, M., Kato, T., Ita, M., Tanabe, T., Ogawa.S.
- Journal Title
  
  Circulation Research 94
  
  Pages: 1242-1248
- Data Source
  KAKENHI-PROJECT-15300121
[Journal Article] Blocking the R-type (Ca_v2.3) Ca^<2+> channel enhanced morphine analgesia and reduced morphine tolerance2004
- Author(s)
  Yokoyama, K., Kurihara, T., Saegusa, H., Zong, S., Makita, K., Tanabe, T.
- Journal Title
  
  Eur.J.Neurosci. 20
  
  Pages: 3516-3519
- Data Source
  KAKENHI-PROJECT-15300121
[Patent] 神経因性疼痛治療剤2010
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Acquisition Date
  2010-09-17
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] Therapeutic agent for neuropathic pain2010
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Acquisition Date
  2010-12-14
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2009
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Acquisition Date
  2009-12-25
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2009
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Acquisition Date
  2009-10-02
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2009
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Acquisition Date
  2009-08-21
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2008
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Acquisition Date
  2008-12-05
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2008
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Acquisition Date
  2008-11-21
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2008
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  科学技術振興機構・東京医科歯科大
- Acquisition Date
  2008-11-28
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2008
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Acquisition Date
  2008-11-28
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2008
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  科学技術振興機構・東京医科歯科大学
- Acquisition Date
  2008-11-28
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2008
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  科学技術振興機構・東京医科歯科大
- Acquisition Date
  2008-12-05
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] 神経因性疼痛治療剤2008
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  科学技術振興機構・東京医科歯科大
- Acquisition Date
  2008-11-21
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] Therapeutic agent for neuropathic pain2007
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  科学技術振興機構・東京医科歯科大学
- Filing Date
  2007-01-15
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] THERAPEUTIC AGENT FOR NEUROPATHIC PAIN2007
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Filing Date
  2007-01-15
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] THERAPEUTIC AGENT FOR NEUROGENIC PAIN2007
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Filing Date
  2007-01-15
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] REMEDY FOR NEUROGENIC PAIN2006
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Filing Date
  2006-02-10
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] AGENT FOR TREATING NEUROPATHIC PAIN2006
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Filing Date
  2006-04-26
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] THERAPEUTIC AGENT FOR NEUROGENIC PAIN2006
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Filing Date
  2006-06-08
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] THERAPEUTIC AGENT FOR NEUROPATHIC PAIN2006
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Filing Date
  2006-08-30
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] THERAPEUTIC AGENT FOR NEUROGENIC PAIN2006
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Filing Date
  2006-09-26
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Patent] PSYCHOGENIC PAIN THERAPEUTIC AGENT2006
- Inventor(s)
  田邊勉
- Industrial Property Rights Holder
  東京医科歯科大学・JST
- Filing Date
  2006-02-10
- Overseas
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Microglial Cav1.2 Ca2+ channel is involved in the pathophysiology of Parkinson's disease2020
- Author(s)
  Xinshuang Wang, Hironao Saegusa, Soontaraporn Huntula, Tsutomu Tanabe
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07840
[Presentation] Roles for microglial N-type Ca2+ channel in aging-related enhanced neuroinflammation2020
- Author(s)
  Hironao Saegusa, Soontaraporn Huntula, Xinshuang Wang, Shuqin Zong, Tsutomu Tanabe
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07840
[Presentation] Upregulation of casein kinase 1ε in dorsal root ganglia and spinal cord contributes to neuropathic pain induced by spinal nerve ligation in mice2011
- Author(s)
  Sakurai, E., Kurihara, T., Miyata, A., Tanabe, T.
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Activation of casein kinase 1δ/ε in dorsal root ganglia and spinal cord contributes to behavioral hypersensitivity induced by peripheral inflammation in mice2011
- Author(s)
  Kurihara, T., Sakurai, E., Asada T., Miyata, A., Tanabe, T.
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Specific blockade of synaptic transmission and behavioral pain responses by casein kinase 1 epsilon inhibitors in neuropathic mice2010
- Author(s)
  Tanabe, T., Sakurai, E., Kurihara, T., Kouchi, K., Saegusa, H., Zong, S.
- Organizer
  The 50th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Searching for downstream molecules of N-type voltage-dependent calcium channels (Cav2.2) contributing to the neuropathic pain2010
- Author(s)
  Tanabe, T., Sakurai, E., Kurihara, T., Kouchi, K., Saegusa, H., Zong, S.
- Organizer
  16th World Congress of Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Inhibitors of casein kinase 1 epsilon are effective in blocking pain in neuropathic mice without showing any appreciable side effect in normal mice2010
- Author(s)
  Tsutomu Tanabe, Eri Sakurai, Takashi Kurihara, Kasumi Kouchi, Hironao Saegusa, Shuqin Zong
- Organizer
  The 40th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Upregulation of casein kinase 1 epsilon after spinal nerve injury contributes to neuropathic pain2010
- Author(s)
  Tanabe, T., Sakurai, E., Kurihara, T., Kouchi, K., Saegusa, H., Zong, S.
- Organizer
  The Third International Congress on Neuropathic Pain
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Upregulation of casein kinase 1 epsilon after spinal nerve injury contributes to neuropathic pain2010
- Author(s)
  Tsutomu Tanabe, Eri Sakurai, Takashi Kurihara, Kasumi Kouchi, Hironao Saegusa, Shuqin Zong
- Organizer
  The Third International Congress on Neuropathic Pain Athens
- Place of Presentation
  Greece
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Identification of the molecules determining cell death vulnerability in a cellular model of spinocerebellar ataxia type 62009
- Author(s)
  T.Tanabe, L.Li, H.Saegusa
- Organizer
  The 39th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2009-10-20
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Heat shock 70kDa protein 1A in a cellular model of spinocerebellar ataxia type 62009
- Author(s)
  T.Tanabe, L.Li, H.Saegusa
- Organizer
  The 49th Annual Meeting of the Americal Society for Cell Biology
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Enhanced stress-induced cell death in HEK293 cells expressing carboxyl-terminal portion of human Cav2.1 with a spinocerebellar ataxia type 6 mutation2009
- Author(s)
  T. Tanabe, L. Li, and H. Saegusa
- Organizer
  Keystone Symposia : Neurodegenerative Diseases : New Molecular Mechanisms
- Place of Presentation
  Keystone CO, USA
- Year and Date
  2009-02-20
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Co-administration of ATP attenuates peripheral type benzodiazepine receptor antagonist-induced antinociception of neuropathic pain.2008
- Author(s)
  T.Tanabe, D.Kondo, R.Yabe, I.Takasaki, T.Kurihara, H.Saegusa, S.Zong
- Organizer
  The 38th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Co-administration of ATP attenuates peripheral type benzodiazepine receptor antagonist-induced antinociception of neuropathic pain2008
- Author(s)
  T. Tanabe, D. Kondo, R. Yabe, I. Takasaki, T. Kurihara, H. Saegusa and S. Zong
- Organizer
  The 38th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Enhanced expression of peripheral-type benzodiazepine receptor induces neuropathic pain through the activation of microglia2008
- Author(s)
  T. Tanabe, D. Kondo, R. Yabe, I. Takasaki, T. Kurihara, H. Saegusa and S. Zong
- Organizer
  The 3rd Asian Pain symposium
- Place of Presentation
  Fukuoka, Japan
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Enhanced expression of peripheral-type benzodiazepine receptor induces neuropathic pain.2007
- Author(s)
  T.Tanabe, D.Kondo, R.Yabe, I.Takasaki, T.Kurihara, H.Saegusa, S.Zong
- Organizer
  The 36th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego CA, USA
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Enhanced expression of peripheral-type benzodiazepine receptor induces neuropathic pain2007
- Author(s)
  T. Tanabe, D. Kondo, R. Yabe, I. Takasaki, T. Kurihara, H. Saegusa and S. Zong
- Organizer
  The 36th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  San Diego CA, USA
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PLANNED-18077002
[Presentation] Involvement of steroid hormone receptors in the maintenance of neuropathic pain.2006
- Author(s)
  T.Tanabe ; D.Kondo, I.Takasaki, R.Yabe, T.Kurihara, H.Saegusa, S.Zong
- Organizer
  The 35rd Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Atlanta, GA, USA
- Data Source
  KAKENHI-PLANNED-18077002

1. 水澤英洋 (30144091)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. IMOTO Keiji (00176512)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. NUMA Shosaku (50025516)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. FUKUDA Kazuhiko (90199224)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. SAKMANN Bert

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAI Junichi (80237198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MURAKOSHI Takayuki (60190906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FUJITA Yoshihiko (80192730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKESHIMA Hiroshi (70212024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 三品昌美 (80144351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 成宮周 (70144350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 三木直正 (40094445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 飯野正光 (50133939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 久保泰 (10178030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 野田昌晴 (60172798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KONNO Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TSIEN Richard W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. BEAM Kurt G.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. STUHMER Walter

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MICHEL Hartmut

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. WALTER Stuhm

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. HARTMUT Mich

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TANABE Tsutomu 田邊 勉

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老化に伴う脳内炎症反応遷延化の要因の同定および制御法の開発Principal Investigator

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Conversion of touch sensation to pain by the modal shift of sensor functionPrincipal Investigator

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脊髄小脳失調症6型の発症機構の解明および予防、治療法の検討Principal Investigator

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Pathogenic mechanism of calcium channelopathyPrincipal Investigator

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カルシウムチャネル遺伝子欠損神経細胞を用いた伝達物質放出制御機構の解析Principal Investigator

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カルシウムチャネル遺伝子欠損神経細胞を用いた伝達物質放出制御機構の解析Principal Investigator

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TANABE Tsutomu 田邊勉