Yokoyama Miki 横山三紀

… Alternative Names

YOKOYAMA Miki 横山三紀

横山三紀ヨコヤマミキ

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Researcher Number	70191533
Other IDs
External Links
Affiliation (Current)	2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2024: 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師 2016 – 2023: 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 2011 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 2010 – 2012: 東京医科歯科大学, 大学院・医歯学総合研究科, 准教授 2005 – 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 助教授 … More 2003 – 2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教授 2001 – 2002: Tokyo Medical and Dental University, Graduate School, Lecturer, 大学院・医歯学総合研究科, 講師 2001: 東京医科歯科大学, 歯学部, 講師 1997 – 2000: 日本大学, 松戸歯学部, 講師 1993: 日本大学, 松戸歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 57060:Surgical dentistry-related / Functional basic dentistry / Social dentistry / Structural biochemistry / Surgical dentistry / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Orthodontics/Pediatric dentistry / Periodontal dentistry / Rehabilitation science/Welfare engineering / Structural biochemistry
Keywords	Principal Investigator シャペロン依存性オートファジー / LAMP-2 / リソソーム / 細胞膜 / エクト型酵素 / CD38 / ガングリオシド / 口腔がん / SECRETORY GRANULES / RAT PAROTID … More / 外分泌腺 / 分泌顆粒 / アセンブリ / LAMP-1 / シグナル伝達 / NAD / 糖脂質 / 脂質修飾 / インフラマソーム / NLRP3 / 細胞運動 / 浸潤 / Rac / LAMP2A / Hsc70 / 膜融合 / 生体防御 / 部位特異的光架橋反応 / オートファゴソーム / 複合体形成 / lysosome / クロスリンク / オートファジー / LAMP2 / 非天然アミノ酸 / 光架橋 / 拡張遺伝暗号 / 膜タンパク質アセンブリ / Antibody / Crosslinking / B cell receptor / 抗体 / 架橋刺激 / B細胞受容体 / GLYCOLIPIDS / CHOLESTEROL / MEMRANE DOMAINS / ホスホリパーゼD / マイクロドメイン / ラット / 膜ドメイン / コレステロール / ADP-RIBOSYLATION FACTOR / SALIVERY GLANDS / EXOCRINE GLANDS / ACINAR CELLS / SMALL-MOLECULAR-MASS GTP-BINDING PROTEINS / ADPリボシレーション因子 / ADPリボシル化因子 / 唾液腺 / 腺房細胞 / 低分子量グアニンヌクレオチド結合タンパク質 / ラット耳下腺 / 骨細胞 / 骨芽細胞 / ミトコンドリア / 細胞内輸送 / LAMP / ネクロプトーシス / S1P / スフィンゴシンキナーゼ / スフィンゴ脂質 / 細胞死 / 口腔生化学 / ニコチンアミドアデニンジヌクレオチド … More Except Principal Investigator プロテオグライカン / heparan sulfate / extracellular matrix / ヘパラネース / 分解酵素 / ヘパラン硫酸 / 細胞外マトリックス / complex carbohydrates / degrading enzyme / molecular interactions / membrane domain / proteoglycan / 糖鎖 / 分子間相互作用 / 膜ドメイン / heparanase / degradation enzyme / Proteoglycan / 骨雅細胞 / エクソソーム / IL-1β / Txnip / Trx1 / 歯周ポケット / ROS / 組織の酸化状態 / TRX / ポケット上皮 / Txnip(thioredoxin interacting protein) / TRX1(チオレドキシン 1) / 酸化ストレス / 歯周免疫機能学 / リハビリテーション医学 / 生体応用 / 超機能性糖鎖 / 構造生物学 / 計算科学 / 高次構造認識 / タンパク質との作用 / 糖鎖コドン / 複合糖質 / ホスファターゼ / オカダ酸 / サイクリックAMP / カルシウム / 脱リン酸化 / 耳下腺 Less

シャペロン依存性オートファジーによるNLRP3の分解：炎症とがんのクロストークPrincipal Investigator
- Principal Investigator
  
  横山三紀
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Medical and Dental University
口腔がんの浸潤・転移を抑える創薬の新たな分子標的、シャペロン依存性オートファジーPrincipal Investigator
- Principal Investigator
  
  横山三紀
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Tokyo Medical and Dental University
Improvement of QOL of cancer treatment patients by oral care based on assembly control of LAMP2Principal Investigator
- Principal Investigator
  
  Yokoyama Miki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Tokyo Medical and Dental University
HSPG-dependent internalization of exosomes and alveolar bone regeneration
- Principal Investigator
  
  Inoue Katarzyna Anna
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tokyo Medical and Dental University
Structural basis of LAMP2 aimed to modulate intracellular trafficking of lysosomePrincipal Investigator
- Principal Investigator
  
  Miki Yokoyama
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University
A new molecular-based rehabilitation for neurodegenerative disease by in situ application of proteoglycan
- Principal Investigator
  
  INOUE Katarzyna
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Tokyo Medical and Dental University
Analysis of the role of Trxl and Txnip under the oxidative stress condition in periodontitis.
- Principal Investigator
  
  EBE Noriko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Periodontal dentistry
- Research Institution
  Tokyo Medical and Dental University
Roles of sphingolipid metabolism on cell death by necroptosisPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Miki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Medical and Dental University
Molecular analysis of B cell receptor activation by Fab-bridgePrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Miki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokyo Medical and Dental University
Regulatory mechanisms and interactions of extracellular molecules
- Principal Investigator
  
  YANAGISHITA Masaki
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Medical and Dental University
生体反応の高次構造認識における糖鎖コドンの化学的解明
- Principal Investigator
  
  古川清
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
糖脂質による細胞表層シグナル伝達タンパク質の配向の制御Principal Investigator
- Principal Investigator
  
  横山三紀
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nihon University
Metabolism of Proteoglycans in the Extracellular Matrix
- Principal Investigator
  
  YANAGISHITA Masaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Medical and Dental University
MEMBRANE DOMAINS IN SECRETORY GRANUES OF RAT PAROTID ACINAR CELLSPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Miki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  NIHON UNIVERSITY
糖脂質による細胞表層シグナル伝達タンパク質の配向の制御Principal Investigator
- Principal Investigator
  
  横山三紀
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nihon University
糖脂質による細胞表層シグナル伝達タンパク質の配向の制御Principal Investigator
- Principal Investigator
  
  横山三紀
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nihon University
BIOGENESIS OF SECRETORY GRANULES IN PAROTID ACINAR CELLSPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Miki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  NIHON UNIVERSITY
耳下腺細胞のカルシウム動員受容体刺激に共役した脱リン酸化
- Principal Investigator
  
  古山俊介
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University

[Book] Sphigolipid Biology (Springer-Verlag)2006
- Author(s)
  Miki Yokoyama
- Total Pages
  8
- Publisher
  Roles of Membrane Domains in the Signaling Pathway for B Cell Survival
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570091
[Book] Studies on Gingivitis and Periodontal Disesase
- Author(s)
  Noriko Ebe, Miki Hara-Yokoyama and Yuichi Izumi
- Total Pages
  10
- Publisher
  Springer Science and Business Media Plus
- Data Source
  KAKENHI-PROJECT-23890058
[Journal Article] Site‐specific photo‐crosslinking/cleavage for protein?protein interface identification reveals oligomeric assembly of lysosomal‐associated membrane protein type 2A in mammalian cells2023
- Author(s)
  Terasawa Kazue、Seike Tatsuro、Sakamoto Kensaku、Ohtake Kazumasa、Terada Tohru、Iwata Takanori、Watabe Tetsuro、Yokoyama Shigeyuki、Hara‐Yokoyama Miki
- Journal Title
  
  Protein Science
  
  Volume: 32 Issue: 12
- DOI
  10.1002/pro.4823
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05821, KAKENHI-PROJECT-21K10063
[Journal Article] The two-domain architecture of LAMP2A within the lysosomal lumen regulates its interaction with HSPA8/Hsc702022
- Author(s)
  Ikami Yuta、Terasawa Kazue、Watabe Tetsuro、Yokoyama Shigeyuki、Hara-Yokoyama Miki
- Journal Title
  
  Autophagy Reports
  
  Volume: 1 Issue: 1 Pages: 205-209
- DOI
  10.1080/27694127.2022.2069968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10063
[Journal Article] The two domain architecture of LAMP2A regulates its interaction with Hsc702022
- Author(s)
  Yuta Ikami, Kazue Terasawa, Kensaku Sakamoto, Kazumasa Ohtake, Hiroyuki Harada Tetsuro Watabe, Shigeyuki Yokoyama, Miki Hara-Yokoyam
- Journal Title
  
  Experimental Cell Research
  
  Volume: 411 Issue: 1 Pages: 112986-112986
- DOI
  10.1016/j.yexcr.2021.112986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02416, KAKENHI-PROJECT-19K05821, KAKENHI-PROJECT-21K10063, KAKENHI-PROJECT-22H02591
[Journal Article] Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cells2021
- Author(s)
  Terasawa Kazue、Kato Yuji、Ikami Yuta、Sakamoto Kensaku、Ohtake Kazumasa、Kusano Seisuke、Tomabechi Yuri、Kukimoto-Niino Mutsuko、Shirouzu Mikako、Guan Jun-Lin、Kobayashi Toshihide、Iwata Takanori、Watabe Tetsuro、Yokoyama Shigeyuki、Hara-Yokoyama Miki
- Journal Title
  
  Autophagy
  
  Volume: 17 Issue: 12 Pages: 1-19
- DOI
  10.1080/15548627.2021.1911017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05821, KAKENHI-PROJECT-17K12005, KAKENHI-PROJECT-18H02416
[Journal Article] Intracellular claudin-1 at the Invasive Front of Tongue Squamous Cell Carcinoma Is Associated With Lymph Node Metastasis2020
- Author(s)
  Daisuke Yamamoto , Kou Kayamori, Kei Sakamoto, Maiko Tsuchiya, Tohru Ikeda, Hiroyuki Harada, Tetsuya Yoda, Tetsuro Watabe, Miki Hara-Yokoyama
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 2 Pages: 700-712
- DOI
  10.1111/cas.14249
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K12005
[Journal Article] The Ceramide Analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide Induces Large Lipid Droplet Accumulation and Highlights the Effect of LAMP-2 Deficiency on Lipid Droplet Degradation2020
- Author(s)
  Yuji Kato, Satoko Arakawa, Kazue Terasawa, Jin-Ichi Inokuchi, Takanori Iwata, Shigeomi Shimizu, Tetsuro Watabe, Miki Hara-Yokoyama
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 3 Pages: 126891-126891
- DOI
  10.1016/j.bmcl.2019.126891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K12005, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-20K07353, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-20H03452
[Journal Article] KIF11 as a Potential Marker of Spermatogenesis Within Mouse Seminiferous Tubule Cross-sections2019
- Author(s)
  Miki Hara-Yokoyama, Hidetake Kurihara, Shozo Ichinose, Hironori Matsuda, Shizuko Ichinose, Masaru Kurosawa, Norihiro Tada, Chihiro Iwahara, Kazue Terasawa, Katarzyna A Podyma-Inoue, Koichi Furukawa , Kazuhisa Iwabuchi
- Journal Title
  
  Journal of Histochemistry & Cytochemistry
  
  Volume: 67 Issue: 11 Pages: 813-824
- DOI
  10.1369/0022155419871027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12005, KAKENHI-PROJECT-18K05691, KAKENHI-PROJECT-18K08221, KAKENHI-PROJECT-19H00456, KAKENHI-PROJECT-16K09375, KAKENHI-PROJECT-18H02628
[Journal Article] PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.2017
- Author(s)
  Takashi O, Katarzyna A. Podyma-Inoue, Kazue T, Jin-ichi I, Toshihide K, Tetsuro W, Yuichi I, Miki Hara-Y.
- Journal Title
  
  Experimental Cell Research
  
  Volume: 350 Issue: 1 Pages: 103-114
- DOI
  10.1016/j.yexcr.2016.11.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04767, KAKENHI-PROJECT-16J07413, KAKENHI-PROJECT-25463072, KAKENHI-PROJECT-26463087, KAKENHI-PROJECT-17K19569
[Journal Article] Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modes.2016
- Author(s)
  Terasawa K, Tomabechi Y, Ikeda M, Ehara H, Kukimoto-Niino M, Wakiyama M, Podyma-Inoue KA, Rajapakshe AR, Watabe T, Shirouzu M, Hara-Yokoyama M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 479 Issue: 3 Pages: 489-495
- DOI
  10.1016/j.bbrc.2016.09.093
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25463072, KAKENHI-PROJECT-26463087
[Journal Article] Characterization of heparan sulfate proteoglycan-positive recycling endosomes isolated from ｇlioma ｃells2016
- Author(s)
  Katarzyna A. Podyma-Inoue, Takuya Moriwaki, Anupama R. Rajapakshe, K Terasawa, M Hara-Yokoyama
- Journal Title
  
  Cancer Genomics Proteomics
  
  Volume: 13 Pages: 443-452
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26463087
[Journal Article] Characterization of Heparan Sulfate Proteoglycan-positive Recycling Endosomes Isolated from Glioma Cells.2016
- Author(s)
  Podyma-Inoue KA, Moriwaki T, Rajapakshe AR, Terasawa K, Hara-Yokoyama M.
- Journal Title
  
  Cancer Genomics Proteomics.
  
  Volume: 13 Pages: 443-452
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463072
[Journal Article] Preferential recognition of isocitrate dehydrogenase by a rabbit monoclonal antibody　 (ab124797) against the C-terminal peptide of RANKL2015
- Author(s)
  Kazue Terasawa, Anupama R. Rajapakshe, Katarzyna A. Podyma-Inoue, Chiemi Mishima-Tsumagari, Masaki Yanagishita and Miki Hara-Yokoyama
- Journal Title
  
  Journal of Immunological Methods
  
  Volume: 420 Pages: 1-10
- DOI
  10.1016/j.jim.2015.03.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463072, KAKENHI-PROJECT-26463087
[Journal Article] Lysosome-associated membrane proteins (LAMPs) regulate intracellular positioning of mitochondria in MC3T3-E1 cells2015
- Author(s)
  Anupama R. Rajapakshe, Katarzyna A. Podyma-Inouea, Kazue Terasawa, Katsuya Hasegawa, Toshimitsu Namba, Yasuhiro Kumei, Masaki Yanagishita and Miki Hara-Yokoyama
- Journal Title
  
  EXPERIMENTAL CELL RESEARCH
  
  Volume: 331 Issue: 1 Pages: 211-222
- DOI
  10.1016/j.yexcr.2014.09.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463072, KAKENHI-PROJECT-26463087
[Journal Article] Sphingosine kinase 2 inhibitor SG-12 induces apoptosis via phosphorylation by sphingosine kinase 22013
- Author(s)
  Miki Hara-Yokoyama, Kazue Terasawa, Shizuko Ichinose, Akihiko Watanabe, Katarzyna A. Podyma-Inoue, Kazunari Akiyoshi, Yasuyuki Igarashi, Masaki Yanagishita
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 23 Pages: 2220-2224
- Data Source
  KAKENHI-PROJECT-22592060
[Journal Article] Glycosylation Regulates CD38 Assembly on the Cell Surface2013
- Author(s)
  Hara-Yokoyama, Miki
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 25 Issue: 146 Pages: 215-225
- DOI
  10.4052/tigg.25.215
- NAID
  130004841378
- ISSN
  0915-7352, 1883-2113
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25463072
[Journal Article] Tetrameric interaction of the ectoenzyme CD38 on the cell surface enables its catalytic and raft-association activities2012
- Author(s)
  Hara-Yokoyama M., Kukimoto-Niino M., Terasawa K., Harumiya S., Podyma-Inoue K. A., Hino N., Sakamoto K., Itoh S., Hashii N., Hiruta Y., Kawasaki N., Mishima-Tsumagari C., Kaitsu Y., Matsumoto T., Wakiyama M., Shirouzu M., Kasama T., Ta
- Journal Title
  
  Structure
  
  Volume: 20 Issue: 9 Pages: 1585-1595
- DOI
  10.1016/j.str.2012.06.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570175, KAKENHI-PROJECT-22592060, KAKENHI-PROJECT-23650319, KAKENHI-PROJECT-23659108, KAKENHI-PROJECT-24657081
[Journal Article] Syndecans reside insphingomyelin-enriched low-density fractions of the plasma membrane isolated from a parathyroid cell line2012
- Author(s)
  Podyma-Inoue KA, Hara-Yokoyama M, Shinomura T, Kimura T, Yanagishita M
- Journal Title
  
  PLoS One
  
  Volume: 7(3)
- Data Source
  KAKENHI-PROJECT-22592060
[Journal Article] Structural basis of interleukin-5 dimerrecognition by its α receptor2012
- Author(s)
  Kusano S, Kukimoto-Niino M, Hino N, Ohsawa N, Ikutani M, Takaki S, Sakamoto K, Hara-Yokoyama M, Shirouzu M, Takatsu K, Yokoyama S
- Journal Title
  
  Protein Sci
  
  Volume: 21 Pages: 850-64
- Data Source
  KAKENHI-PROJECT-22592060
[Journal Article] Tetrameric interaction of the ectoenzyme CD38 on the cell surface enables its catalytic and raft-association activities2012
- Author(s)
  Miki Hara-Yokoyama, Mutsuko Kukimoto-Niino, Kazue Terasawa, Satoru Harumiya, Katarzyna A. Podyma-Inoue, Nobumasa Hino, Kensaku Sakamoto, Satsuki Itoh, Noritaka Hashii, Yoko Hiruta, Nana Kawasaki, Chiemi Mishima-Tsumagari, Yoko Kaitsu, Tomoko Matsumoto, Motoaki Wakiyama, Mikako Shirouzu, Takeshi Kasama, Hiroshi Takayanagi, Naoko Utsunomiya-Tate, Kiyoshi Takatsu, Toshiaki Katada, Yoshio Hirabayashi, Shigeyuki Yokoyama and Masaki Yanagishita
- Journal Title
  
  Structure
  
  Volume: 20 Pages: 1-11
- Data Source
  KAKENHI-PROJECT-22592060
[Journal Article] Pocket epithelium in the pathological setting for HMGB1 release2011
- Author(s)
  Ebe N, Hara-Yokoyama M, Iwasaki K, Iseki S, Okuhara S, Podyma-Inoue KA, Terasawa K, Watanabe A, Akizuki T, Watanabe H, Yanagishita M, Izumi Y
- Journal Title
  
  Journal of Dental Reserch
  
  Volume: 90 Pages: 235-40
- Data Source
  KAKENHI-PROJECT-22592060
[Journal Article] Survival signals of hepatic stellate cells in liver regeneration are regulated by glycosylation changes in rat vitronectin, especially decreased sialylation2010
- Author(s)
  Sano K, Miyamoto Y, Kawasaki N, Hashii N, Itoh S, Murase M, Date K, Yokoyama M, Sato C, Kitajima K, Ogawa H
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 17301-17309
- Data Source
  KAKENHI-PROJECT-22592060
[Journal Article] Gangliosides Potentially Inhibit Extracellular Nucleotide Metabolism2006
- Author(s)
  Miki Hara-Yokoyama
- Journal Title
  
  Current Medicinal Chemistry 13(19)
  
  Pages: 2233-2239
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570091
[Journal Article] Roles of Membrane Domains in the Signaling Pathway for B Cell Survival2006
- Author(s)
  Miki Yokoyama, et al.
- Journal Title
  
  Sphigolipid Biology (Springer-Verlag)
  
  Pages: 245-251
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570091
[Journal Article] Effects of p-nitrophenyl-xyloside on the biosynthesis of proteoglycans in rat ovarian granulosa cells - analysis of carbohydrate biosynthesis in the Golgi apparatus2006
- Author(s)
  Yanagishita, M., Tsuchida, S., Yokoyama, M., Inoue, K.-A.
- Journal Title
  
  J.Stomatological Society 73
  
  Pages: 20-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Journal Article] Gangliosides Potentially Inhibit Extracellular Nucleotide Metabolism2006
- Author(s)
  Miki Yokoyama
- Journal Title
  
  Current Medicinal Chemistry 13
  
  Pages: 2223-2239
- Data Source
  KAKENHI-PROJECT-17570091
[Journal Article] Charge-based separation of detergent-resistant membranes of mouse splenic B cells.2004
- Author(s)
  Katsumata, O., Kimura, T., Nagatsuka, Y., Hirabayashi, Y., Sugiya, H., Furuyama, S., Yanagishita, M., Hara-Yokoyama, M.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 319
  
  Pages: 826-831
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Journal Article] Carbohydrate-dependent signaling from the phosphatidylglucoside-based microdomain induces granulocytic differentiation of HL60 cells,2003
- Author(s)
  Yasuko Nagatsuka, Miki Hara-Yokoyama, Takeshi Kasama, Masataka Takekoshi, Fumiko Maeda, Seiji Ihara, Shigeyoshi Fujiwara, Eriko Ohshima, Kumiko Ishii, Toshihide Kobayashi, Kazufumi Shimizu, Yoshio Hirabayashi
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 100
  
  Pages: 7454-7459
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Journal Article] Novel sulfated gangliosides, high-affinity ligands for neural siglecs, inhibit NADase activity of leukocyte cell surface antigen CD38,2003
- Author(s)
  Hara-Yokoyama, M., Ito, H., Ueno-Noto, K., Takano, K., Ishida H., Kiso, M.
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letter 13
  
  Pages: 3441-3445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Journal Article] Novel sulfated gangliosides, high-affinity ligands for neural siglecs, inhibit NADase activity of leukocyte cell surface antigen CD382003
- Author(s)
  Hara-Yokoyama, M.ら
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letter 13
  
  Pages: 3441-3445
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Journal Article] Role of membrane domain in IgG-Fc receptor cross-linking : Importance of tyrosine phosphorylation and generation of active oxygen species2002
- Author(s)
  Katsumata, O., Yokoyama, M.
- Journal Title
  
  P.N.E. 47
  
  Pages: 379-384
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Journal Article] High-level recognition system of carbohydrate-codon2002
- Author(s)
  Yokoyama, M.
- Journal Title
  
  P.N.E. 47
  
  Pages: 187-188
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Journal Article] Involvement of phospholipase D in the cAMP-regulated exocytosis of rat parotid acinar cells.2002
- Author(s)
  Dohke, Y., Fujita-Yoshigaki, J., Sugiya, H., Furuyama, S., Hara-Yokoyama, M.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 299
  
  Pages: 663-668
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Journal Article] 糖鎖コドンの高次構造認識機構の解明2002
- Author(s)
  横山三紀
- Journal Title
  
  タンパク質核酸酵素 47
  
  Pages: 187-188
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207076
[Patent] タンパク質における別のタンパク質と相互作用する部位の特定方法2023
- Inventor(s)
  横山　三紀
- Industrial Property Rights Holder
  横山　三紀
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-098438
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21K10063
[Presentation] シャペロン依存性オートファジーの必須因子であるLAMP2A分子がリソソーム膜で形成する複合体の構造2023
- Author(s)
  寺澤　和恵、清家　達朗、坂本　健作、大竹　和正、寺田　透、渡部　徹郎、横山　茂之、横山　三紀
- Organizer
  第96回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10063
[Presentation] シャペロン依存性オートファジーの必須因子であるLAMP2A分子の多量体形成2023
- Author(s)
  清家達朗、寺澤和恵、坂本健作、大竹和正、寺田透、渡部徹郎、横山茂之、横山三紀
- Organizer
  第96回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K10063
[Presentation] リソソーム内腔側に存在するLAMP2Aのbプリズムドメイン同士の相互作用はシャペロン依存性オートファジーに重要である2022
- Author(s)
  寺澤　和恵、井神　優太、清家　達朗、坂本　健作、渡部　徹郎、横山　茂之、横山　三紀
- Organizer
  第95回日本生化学会　シンポジウム『細胞内シグナルの開始・継続・終焉に働く多様なタンパク質分解機構」
- Data Source
  KAKENHI-PROJECT-21K10063
[Presentation] 二つのbeta-プリズムドメインをもつLAMP-1, LAMP-2は異なるアセンブリ様式を示す2018
- Author(s)
  寺澤和恵、草野清輔、横山茂之、渡部徹郎、横山三紀
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K12005
[Presentation] Characterization of extracellular vesicles isolated from osteoblastic cells lines2016
- Author(s)
  Katarzyna A. Podyma-Inoue, Miki Yokoyama and Tetsuro Watabe
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター (宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-26463087
[Presentation] Lysosome-associated membrane protein 1/2によるミトコンドリア細胞内輸送の制御2015
- Author(s)
  横山　三紀
- Organizer
  第57回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県、新潟市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25463072
[Presentation] Heparan sulfate proteoglycan and intracellular transport; clues from proteomic analysis of transport vesicles2015
- Author(s)
  Katarzyna A. Podyma-Inoue, Anupama R. Rajapakshe, Takuya Moriwaki, Tetsuro Watabe and Miki Yokoyama
- Organizer
  BMB2015（第 38回日本分子生物学会年会、第 88回日本生化学会大会）
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26463087
[Presentation] Heparan sulfate proteoglycan and intracellular transport; clues from proteomic analysis of transport vesicles2015
- Author(s)
  Podyma-Inoue KA, Rajapakshe AR, Takuya Moriwaki, Teturo Watabe, and Miki Yokoyama
- Organizer
  BMB2015 第38回日本分子生物学会大会、第88回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25463072
[Presentation] LAMP2 is invovled in the intracellular transport of RANKL2013
- Author(s)
  Rajapakse Anupama, 井上　カタジナアンナ、柳下　正樹、横山　三紀
- Organizer
  第５５回　歯科基礎医学会学術大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25463072
[Presentation] Cell surface heparan sulfate proteoglycans expressed by glioma cells : biochemical characterization2013
- Author(s)
  Katarzyna A. Inoue, Miki Y okoyama, and Masaki Yanagishita
- Organizer
  The 8th International Conference on Proteoglycans
- Place of Presentation
  Frankfurkt aim Main, Germany
- Data Source
  KAKENHI-PROJECT-23650319
[Presentation] Cell surface heparan sulfate proteoglycans expressed by glioma cells: biochemical characterization.2013
- Author(s)
  Katarzyna A. Podyma-Inoue, Miki Yokoyama and Masaki Yanagishita
- Organizer
  The 8th International Conference on Proteoglycans
- Place of Presentation
  Frankfurt/Main, Germany
- Data Source
  KAKENHI-PROJECT-23650319
[Presentation] Association of heparan sulfate proteoglycans with trypsin-accessible membrane domains2012
- Author(s)
  Katarzyna A. Inoue, Miki Y okoyama, and Masaki Y anagishita
- Organizer
  The Gordon Research Conference on Proteoglycans
- Place of Presentation
  Proctor Academy , Andover , USA
- Data Source
  KAKENHI-PROJECT-23650319
[Presentation] Association of heparan sulfate proteoglycans with trypsin-accessible membrane domains2012
- Author(s)
  Katarzyna A. Podyma-Inoue, Miki Yokoyama and Masaki Yanagishita
- Organizer
  Gordon Research Conference Proteoglycans
- Place of Presentation
  Proctor Academy, Andover - U.S.A.
- Data Source
  KAKENHI-PROJECT-23650319
[Presentation] Characterization of membrane rafts enriched in cell surface heparan sulfate proteoglycans isolated from a rat parathyroid cell line2011
- Author(s)
  Katarzyna A. Inoue, Miki Yokoyama and Masaki Yanagishita
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23650319
[Presentation] Plasma membrane permeabilization-associated cell death induced by intracellular generation of sphingosine-1-phosphate2011
- Author(s)
  横山三紀
- Organizer
  第30回内糖コンファレンス
- Place of Presentation
  シャトレーゼガトーキングダム(札幌)
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] リンパ球表面抗原CD38の四量体化を反映したN型糖鎖プロセシング2011
- Author(s)
  横山三紀
- Organizer
  第30回日本糖質学会
- Place of Presentation
  長岡リリックホール
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] 酪酸による酸化ストレス誘導時に放出されるHMGB1の解析2011
- Author(s)
  江部典子,横山三紀,寺澤和恵,柳下正樹,和泉雄一
- Organizer
  第135回日本歯科保存学会2011年度秋季学術大会
- Place of Presentation
  大阪,大阪国際交流センター
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23890058
[Presentation] 酪酸による酸化ストレス誘導時に放出されるHMGB1の役割2011
- Author(s)
  江部典子、横山三紀、寺澤和恵、柳下正樹、和泉雄一
- Organizer
  第135回日本歯科保存学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] CD38 の触媒活性と膜ドメイン局在化を両立させている細胞表面アセンブリの構造基盤2011
- Author(s)
  YOKOYAMA Miki, YOKOYAMA Shigeyuki, YANAGISHITA MASAKI
- Organizer
  第40回日本免疫学会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] Characterization of membrane rafts enriched in cell surface heparan sulfate proteoglycans isolated from a rat parathyroid cell line2011
- Author(s)
  Katarzyna A. Inoue, Miki Y okoyama, and Masaki Y anagishita
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都市, 国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23650319
[Presentation] CD38の触媒活性と膜ドメイン局在化を両立させている細胞表面でのアセンブリの構造基盤2011
- Author(s)
  横山三紀
- Organizer
  日本免疫学会総会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] セラミド産生にともなうリソソーム関連膜構造物2011
- Author(s)
  横山三紀
- Organizer
  第53回日本脂質生化学会
- Place of Presentation
  ホテル東京ガーデンパレス
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] Yanagishita, Characterization of Membrane Rafts Enriched in Cell Surface Heparan Sulfate Proteoglycans Isolated from a Rat Parathyroid Cell Line2011
- Author(s)
  Katarzyna A. Podyma-Inoue, Miki Yokoyama, and Masaki
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] セラミド産生にともなうリソソーム関連膜構造物2011
- Author(s)
  横山三紀、寺澤和恵、市野瀬志津子、柳下正樹
- Organizer
  第53回日本脂質生化学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] リンパ球表面抗原CD38の四量体化を反映したN型糖鎖プロセシング2011
- Author(s)
  横山三紀、新野睦子、寺澤和恵、橋井則貴、蛭田葉子、川崎ナナ、脇山素明、白水美香子、横山茂之、柳下正樹
- Organizer
  第30回日本糖質学会
- Place of Presentation
  長岡
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] GM2/GD2合成酵素欠損マウスにおける血液-精巣関門の異常2011
- Author(s)
  横山三紀
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] GM2/GD2 合成酵素欠損マウスにおける血液ー精巣関門の異常2011
- Author(s)
  横山三紀、市野瀬志津子、市野瀬省三、多田昇弘、寺澤和恵、吉垣純子、只野ー有冨桂子、古川鋼一、柳下正樹、岩渕和久
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] Plasma membrane permeabilization-associated cell death induced by intracellular generation of sphingosine-1-phosphate2011
- Author(s)
  Miki Yokoyama, Kazue Terasawa, ShizukoIchinose, Yoshiko Banno, YoshioHirabayashi, Yasuyuki Igarashi, Masaki Yanagishita
- Organizer
  The 30^<th> NAITO CONFERENCE ON Membrane Dynamics and Lipid Biology [II]
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] スフィンゴシンキナーゼ2に依存した細胞膜透過性の亢進2010
- Author(s)
  横山三紀
- Organizer
  第5回スフィンゴテラピー会議
- Place of Presentation
  米子
- Year and Date
  2010-07-17
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] Increase in the plasma membrane permeability by intracellular generation of sphingosine-1-phosphate2010
- Author(s)
  Miki Yokoyama, Kazue Terasawa, ShizukoIchinose, Yoshiko Banno, YoshioHirabayashi, Yasuyuki Igarashi, Masaki Yanagishita
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] スフィンゴシンキナーゼ2の酵素活性に依存したスフィンゴ脂質誘導体化合物による細胞死誘導2010
- Author(s)
  横山三紀、寺澤和恵、五十嵐靖之、平林義雄、柳下正樹
- Organizer
  第52回日本脂質生化学会
- Place of Presentation
  伊香保
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] Increase in the plasma membrane permeability by intracellular gelleration of sphingosine-1-phosphate2010
- Author(s)
  横山三紀
- Organizer
  BMB2010(第83回日本生化学会大会・第33回日本分子生物学会年会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] スフィンゴシンキナーゼ2の酵素活性に依存したスフィンゴ脂質誘導体化合物による細胞死誘導2010
- Author(s)
  横山三紀
- Organizer
  第52回日本脂質生化学会
- Place of Presentation
  伊香保
- Year and Date
  2010-06-15
- Data Source
  KAKENHI-PROJECT-22592060
[Presentation] Heparan sulfate proteoglycan and its putative role in trafficking of transglutaminase 2
- Author(s)
  Katarzyna Anna Podyma-Inoue, Miki Yokoyama and Masaki Yanagishita
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26463087

1. INOUE Katarzyna (90302877)

# of Collaborated Projects: 5 results

# of Collaborated Products: 21 results
2. YANAGISHITA Masaki (70132793)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. 横山茂之 (00159229)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KUMEI Yasuhiro (30161714)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHINOMURA Tamayuki (70206118)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. ZEREDO Jorge (10363459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HASEGAWA Katsuya (30425780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. EBE Noriko (20611099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. ISEKI Sachiko (80251544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IZUMI Yuichi (60159803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. SAKAMOTO Kensaku (50240685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. SHIROUZU Mikako (70280732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. KIMURA Tomoko (90376731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 古山俊介 (50050034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 横山紀子 (40112958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 古川清 (10190133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 加藤晃一 (20211849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 鷹野景子 (00143701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 小川温子 (90143700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 畑中保丸 (30111181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 渡一平 (10431941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TERASAWA Kazue

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
23. RAJAPAKSHE R.M.A.R

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. HINO Nobumasa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 大竹和正

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yokoyama Miki 横山 三紀

YOKOYAMA Miki 横山 三紀

横山 三紀 ヨコヤマ ミキ

Research Projects

Research Products

Co-Researchers

シャペロン依存性オートファジーによるNLRP3の分解：炎症とがんのクロストークPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

口腔がんの浸潤・転移を抑える創薬の新たな分子標的、シャペロン依存性オートファジーPrincipal Investigator

Principal Investigator

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Improvement of QOL of cancer treatment patients by oral care based on assembly control of LAMP2Principal Investigator

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HSPG-dependent internalization of exosomes and alveolar bone regeneration

Principal Investigator

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Structural basis of LAMP2 aimed to modulate intracellular trafficking of lysosomePrincipal Investigator

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A new molecular-based rehabilitation for neurodegenerative disease by in situ application of proteoglycan

Principal Investigator

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Analysis of the role of Trxl and Txnip under the oxidative stress condition in periodontitis.

Principal Investigator

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Roles of sphingolipid metabolism on cell death by necroptosisPrincipal Investigator

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Molecular analysis of B cell receptor activation by Fab-bridgePrincipal Investigator

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Regulatory mechanisms and interactions of extracellular molecules

Principal Investigator

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生体反応の高次構造認識における糖鎖コドンの化学的解明

Principal Investigator

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Research Institution

糖脂質による細胞表層シグナル伝達タンパク質の配向の制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Metabolism of Proteoglycans in the Extracellular Matrix

Principal Investigator

Project Period (FY)

Yokoyama Miki 横山三紀

YOKOYAMA Miki 横山三紀

横山三紀ヨコヤマミキ