TAIRA Takahiro 平敬宏

… Alternative Names

TAKRA Takahiro.Y. 平敬宏

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Researcher Number	70197036
External Links
Affiliation (Current)	2025: 東邦大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2013 – 2015: 東邦大学, 医学部, 教授 2009 – 2011: University of Yamanashi, 大学院・医学工学総合研究部, 教授 2006: University of Yamanashi, Interdisciplinary Graduate School of Medicine and Engineering, Professor, 大学院医学工学総合研究部, 教授 2005: 山梨大学, 大学院・医学工学総合研究部, 教授 2005: Yamanashi Univ., Grad.School of Med., Professor, 大学院・医学総合研究部, 教授 … More 1999 – 2004: Hokkaido Univ., Grad. School of Pharm. Sci., Asso. Prof., 大学院・薬学研究科, 助教授 1998: Grad.School of Pharm.Sci.Hokkaido Univ., 大学院・薬学研究科, 助手 1998: 北海道大学, 大学院薬学研究科, 助手 1994 – 1997: 北海道大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Respiratory organ internal medicine Except Principal Investigator Biological Sciences / Biological pharmacy / Neurology / Ophthalmology / Drug development chemistry / Science and Engineering
Keywords	Principal Investigator c-myc / c-fms / MM-1 / c-Myc / 細胞周期 / hsp70 / 酸化ストレス / DJ-1 / 癌遺伝子 / 転写調節 … More / proteasome / tumor suppressor / ubiquitin / リンパ腫 / タンパク質分解 / プロテアソーム / 癌抑制遺伝子 / ユビキチン / CBF / 細胞死 / 神経変性疾患 / パーキンソン病 / 転写制御 / 癌化 / 転写因子 / DNA複製 / reactive oxygen species / Oxidative stress / Parkinson's disease / 病態モデル動物 / 神経変成疾患 / 病態モデル / transcriptional regulation / Wnt signal / コレプレッサー / C-fms / Wntシグナル / protein degradation / tumorgenesis / コリプレッサー / 発ガン / cell cycle / transcription / NN-Y / 転写 / hsp70遺伝子 / 細胞癌化 / MYC / NF-Y / 薬物輸送体 / シグナル伝達 / 炎症 / 慢性閉塞生肺疾患 / 薬物輸送担体 / 慢性閉塞性肺疾患 / DJ-1タンパク質 / アストロサイト / 神経膠細胞 / 神経細胞 / 熱ショックタンパク質 / エンハンサー … More Except Principal Investigator c-Myc / タンパク質分解 / 癌抑制遺伝子 / リン酸化 / c-myc / MM-1 / 癌遺伝子 / 細胞周期 / Pim-1 / プロテアーゼ / DJ-1 / ユビキチン / リンパ腫 / 転写因子 / クロマチン / 転写制御 / co-repressor / BIG2 / AMY-1 / RP9 / PAP-1 / tumor suppressor / 精子形成 / phosphorylation / apoptosis / cell cycle / アポトーシス / MYC / ゲノム / 神経変性疾患 / プロテオーム / 遺伝学 / 神経科学 / がん / 転写調節 / SUMO-1 / ミトコンドリア / 酸化ストレス / パーキンソン病 / c-fms / プロテアソーム / コリプレッサー / 発ガン / genome / neurodegenerative disease / proteome / Genomics / Neuroscience / 神細細胞死 / ubiquitin / Golgi apparatu / protein degradatin / PKA / AKAP / ゴルジ体 / retina / splicing / retinitis pigmentosa / c-MYc / 網膜 / スプライシング / 網膜性色素変性症 / spermatogenesis / embryonic lethal / transcription factor / transformation / oncogene / 胎生致死 / chromatin / transcrition / tumor suppresser / PRC1 / ORC1 / DNA replication / transcroption / cell transformation / cDNAクローニング / DNA複製 / 転写 / 細胞癌化 / 基質特異性 / 酵素 / 感染症 / 抗ウイルス薬 / プロセッシング / 創薬 / ウイルス / 制御蛋白 / STAT3 / シグナル伝達 / サイトカイン / 神経細胞死 / コレプレッサー / パーキンソン氏病 / 活性酸素 / 受精 / 内分泌攪乱物質 / アンドロゲン受容体 / 癌化 / プロテインキナーゼ / 蛋白間相互作用 / 転写活性化 / 細胞因子 / HIV Tat Less

Effect of respiratory disease onset and functionality in the alveolar-bronchial of oxidative stress defense protein DJ-1Principal Investigator
- Principal Investigator
  
  TAIRA Takahiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Toho University
Study on transcriptional activation mechanism of DJ-1 gene(PARK7) and the trial to Parkinson's disease cure developmentPrincipal Investigator
- Principal Investigator
  
  TAIRA Takahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Yamanashi
functional analysis of human herpesvirus encoded kinases
- Principal Investigator
  
  FUJIMURO Masahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto Pharmaceutical University
  University of Yamanashi
パーキンソン病PARK7の原因遺伝子DJ-1の機能解析
- Principal Investigator
  
  有賀寛芳
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Functional analysis of DJ-1, a causative gene product for familial Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  TAIRA Takahiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Yamanashi
パーキンソン病PARK7の原因遺伝子DJ-1の構造と機能
- Principal Investigator
  
  有賀寛芳
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
サイトカインシグナル伝達系におけるSTAT3制御蛋白の役割
- Principal Investigator
  
  松田正
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Function of DJ-1, a causative gene for familial Parkinson's disease PARK7
- Principal Investigator
  
  ARIGA Sanae
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  HOKKAIDO UNIVERSITY
新規c-Myc結合タンパク質MM-1のがん抑制遺伝子産物としての機能
- Principal Investigator
  
  有賀早苗
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Function of MM-1, a novel c-Myc-binding protein, as a tumor suppressorPrincipal Investigator
- Principal Investigator
  
  TAIRA Takahiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
新規c-Myc結合タンパク質MM-1のがん抑制遺伝子産物としての機能
- Principal Investigator
  
  有賀早苗
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
内分泌攪乱物質のターゲットタンパク質DJ-1の機能解析
- Principal Investigator
  
  有賀寛芳
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Hokkaido University
Function of PAP-1,a causative gene for retinitis pigmentosa
- Principal Investigator
  
  ARIGA Sanae
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  HOKKAIDO UNIVERSITY
Functions of Myc and c-Myc-binding proteins
- Principal Investigator
  
  ARIGA Hiroyoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
新規C-Myc結合タンパク質MM-1がん抑制遺伝子産物としての機能
- Principal Investigator
  
  有賀早苗
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Function of MM-1, a novel c-Myc-binding protein, as a tumor suppressorPrincipal Investigator
- Principal Investigator
  
  TAIRA Takahiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
新規c-Myc結合タンパク質MM-1のがん抑制遺伝子産物としての機能
- Principal Investigator
  
  ARIGA Sanae
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Regulation of cell-cycle movement and cell transformation by c-Myc and its binding proteins
- Principal Investigator
  
  ARIGA Hiroyoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
Regulation of cell-cycle movement and cell transformation by nuclear oncogenes.
- Principal Investigator
  
  ARIGA Hiroyoshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
CELL-CYCLE DEPENDENT REGULATION OF HSP70 GENE EXPRESSION BY C-MYCPrincipal Investigator
- Principal Investigator
  
  TAIRA Takahiro
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
c-mycによる熱ショックタンパク質70(hsp70)遺伝子の発現制御と細胞周期Principal Investigator
- Principal Investigator
  
  平敬宏
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Molecular mechanism of cell proliferation and appoptosis by the actions of transcription/replication factors in mammalian cells.
- Principal Investigator
  
  ARIGA Hiroyoshi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
HIV-Tatに相互作用する細胞因子のクローン化と機能解析
- Principal Investigator
  
  加藤宏幸
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
c-mycによる熱ショックタンパク質70(hsp70)遺伝子の発現制御と細胞周期Principal Investigator
- Principal Investigator
  
  平敬宏
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
熱ショックタンパク質70(hsp70)遺伝子の発現制御とmycPrincipal Investigator
- Principal Investigator
  
  平敬宏
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University

All 2014 2012 2011 2010 2009 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] 別冊・医学のあゆみ,「パーキンソン病」-最新動向2005
- Author(s)
  有賀寛芳, 有賀早苗, 平敬宏
- Total Pages
  150
- Publisher
  医歯薬出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390248
[Book] 別冊・医学のあゆみ,「パーキンソン病」-最新動向2005
- Author(s)
  有賀寛芳, 有賀早苗, 平敬宏
- Total Pages
  150
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-17025001
[Book] 別冊・医学のあゆみ,「パーキンソン病」最新動向2005
- Author(s)
  有賀寛芳, 有賀早苗, 平敬宏
- Total Pages
  150
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-16390248
[Journal Article] Sangivamycin induces apoptosis by suppressing Erk signaling in primary effusion lymphoma cells.2014
- Author(s)
  Wakao K, Watanabe T, Takadama T, Ui S, Shigemi Z, Kagawa H, Higashi C, Ohga R, Taira T, Fujimuro M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 444 Pages: 135-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461184
[Journal Article] The ubiquitin system and Kaposi's sarcoma-associated herpesvirus2012
- Author(s)
  Ashizawa A, Higashi C, Masuda K, Ohga R, Taira T and Fujimuro M
- Journal Title
  
  Frontiers in Vrology
  
  Volume: 3 Pages: 66-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590113
[Journal Article] The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells2012
- Author(s)
  Higashi C, Saji C, Yamada K, Kagawa H, Ohga R, Taira T, Fujimuro M
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 35 Pages: 725-730
- NAID
  130001872231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590113
[Journal Article] The Ubiquitin System and Kaposi's Sarcoma-Associated Herpesvirus2012
- Author(s)
  Ashizawa A, Higashi C, Masuda K, Ohga R, Taira T, Fujimuro M.
- Journal Title
  
  Front. Microbiol
  
  Volume: 3 Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] Protection against dopaminergic neurodegeneration in Parkinson's disease-model animals by amodulator of the oxidized form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK72011
- Author(s)
  Inden M, Kitamura Y, Takahashi K, Takata K, Ito N, Niwa R, Funayama R, Nishimura K, Taniguchi T, Honda T, Taira T, Ariga H.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 117(3) Pages: 189-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] The protocadherins, PCDHB1 and PCDH7, are regulated by MeCP2 in neuronal cells and brain tissues : implication for pathogenesis of Rett syndrome2011
- Author(s)
  Miyake K, Hirasawa T, Soutome M, Itoh M, Goto Y, Endoh K, Takahashi K, Kudo S, Nakagawa T, Yokoi S, Taira T, Inazawa J, Kubota T.
- Journal Title
  
  BMC Neurosci
  
  Volume: 8 ; 12 Pages: 81-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] S. M. M.(2010) Human DJ-1-specific transcriptional activation of tyrosine hydroxylase gene2010
- Author(s)
  Ishikawa, S., Taira, T., Takahashi-Niki, K., Niki, T., Ariga, H. and Iguchi-Ariga
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 39718-39721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] Oxidative neurodegeneration is prevented by UCP0045037, an allosteric modulator for the reduced form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK72009
- Author(s)
  Yamane, K., Kitamura, Y., Yanagida, T., Takata, T., Yanagisawa, D., Taniguchi, T., Taira, T. and Ariga, H.
- Journal Title
  
  Int. J. Mol. Sci
  
  Volume: 10(11) Pages: 4789-4804
- NAID
  120001720441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] S. M. M.(2009) Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and4-dihydroxy-1-phenylalanine(1-DOPA) decarboxylase with DJ-12009
- Author(s)
  Ishikawa, S., Taira, T., Niki, T., Takahashi-Niki, K., Maita, C., Maita, H., Ariga, H. and Iguchi-Ariga
- Journal Title
  
  J. Biol. Chem
  
  Volume: 284 Pages: 28832-28844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice2009
- Author(s)
  Inden, M., Kitamura, Y., Tamaki, A., Yanagida, T., Shibaike, T., Yamamoto, A., Takata, K., Yasui, H., Taira, T., Ariga, H. and Taniguchi, T.
- Journal Title
  
  Neurochem. Int
  
  Volume: 55(8) Pages: 760-767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury2009
- Author(s)
  Yanagida, T., Tsushima, J., Kitamura, Y., Yanagisawa, D., Takata, K., Shibaike, T., Yamamoto, A., Taniguchi, T., Yasui, H., Taira, T., Morikawa, S., Inubushi, T., Tooyama, I. and Ariga, H.
- Journal Title
  
  Oxidative Medicine & Cellular Longevity
  
  Volume: 1 Pages: 36-42
- NAID
  120005350101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] S. M. M.(2009) DJ-1 binds to mitochondrial complex I and maintains its activity.2009
- Author(s)
  Hayashi, T., Ishimori, C., Takahashi-Niki, K., Taira, T., Kim, Y-C., Maita, H., Maita, C., Ariga, H. and Iguchi-Ariga
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 390 Pages: 667-672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN2009
- Author(s)
  Kim, Y.-C., Kitaura, H., Taira, T., Iguchi-Ariga, S. M. M. and Ariga, H.
- Journal Title
  
  Int. J. Oncol
  
  Volume: 35 Pages: 1331-1341
- NAID
  120002646831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] Protection against oxida tive stress-induced neurodegeneration by amodulator for DJ-1, a wild-type of familial Parkinson's disease-linked PARK72009
- Author(s)
  Yanagida, T., Kitamura, Y., Yamane, K., Takahashi, K., Takata, K., Yanagisawa, D., Yasui, H., Taniguchi, T., Taira, T., Honda, T. and Ariga, H.
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 109 Pages: 463-468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590091
[Journal Article] Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone.2007
- Author(s)
  Inden, M., Kitamura, Y., Takeuchi, H., Yanagida, T., Takata, K., Kobayashi, Y., Taniguchi, T., Yoshimoto, K., Kaneko, M., Okuma, Y., Taira, T., Ariga, H., Shimohama, S.
- Journal Title
  
  J. Neurochem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] DJ-1 degrades transthyretin and an inactive form of DJ-1 is secreted in familial amyloidotic polyneuropathy.2007
- Author(s)
  Koide-Yoshida, S., Niki, T., Ueda, M., Himeno, S., Taira, T., Iguchi-Ariga, S.M.M., Ando, Y., Ariga, H.
- Journal Title
  
  Int. J. Mol. Med. 19
  
  Pages: 885-893
- NAID
  120005350114
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Distribution of DJ-1, Parkinson's disease-related protein PARK7, and its alteration in 6-hydroxydopamine-treated hemiparkinsonian rat brain.2006
- Author(s)
  Yanagida, T., Takada, K., Inden, M., Kitamura, Y., Taniguchi, T., Yoshimoto, K., Taira, T., Ariga, H.
- Journal Title
  
  J. Pharmacol. Sci. 102
  
  Pages: 243-247
- NAID
  10020345801
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities.2006
- Author(s)
  Shinbo, Y., Niki, T., Taira, T., Ooe, H., Takahashi-Niki, K., Maita, C Seino, C., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Cell Death Diff. 13
  
  Pages: 96-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Distinct Localizations and Repression Activities of MM-1 Isoforms toward c-Myc2006
- Author(s)
  Hagio, Y., Kimura, Y., Taira, T., Fujioka, Y., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  J. Cell. Biochem. 97
  
  Pages: 145-155
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model.2006
- Author(s)
  Inden, M., Taira, T., Kitamura, Y., Yanagida, T., Tsuchiya, D., Takata, K., Yanagisawa, D., Nishimura, K., Taniguchi, T., Kiso, Y., Yoshimoto, Y., Wagatsuma, T., Koide-Yoshida, S., Iguchi-Ariga, S.M.M., Shimohama, S., Ariga, H.
- Journal Title
  
  Neurobiol. Dis. 24
  
  Pages: 144-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] DJ-1 interacts with HIPK1 and affects H202-induced cell death.2006
- Author(s)
  Sekito, A., Koide-Yoshida, S., Niki, T., Taira, T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Free Radic. Res. 40
  
  Pages: 155-165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Protection against nonylphenol-induced cell death by DJ-1 in cultured Japanese medaka (Oryzias latipes) cells2006
- Author(s)
  Li, H.M., Taira, T., Maita, C., Ariga, H., Iguchi-Ariga, S.M.M.
- Journal Title
  
  Toxicology 228
  
  Pages: 229-238
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Stimulation of transforming activity of DJ-1 by Abstrakt, a DJ-1-binding protein.2005
- Author(s)
  Shinbo, Y., Taira, T., Niki, T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Int.J.Oncol. 26
  
  Pages: 685-689
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Structure and characterization of AAT-1 isoforms2005
- Author(s)
  Matsuda, E., Ishizaki, R., Taira, T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Biol. Pharm. Bull. 28
  
  Pages: 898-901
- NAID
  120005350119
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] DJ-1 restores p53 transcription activity inhibited by Topors/p53BP3.2005
- Author(s)
  Shinbo, Y., Taira, T., Niki, T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Int. J. Oncol. 26
  
  Pages: 641-648
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Induction of reactive oxygen species by bisphenol A and abrogation of bisphenol A-induced cell injury by DJ-1.2005
- Author(s)
  Ooe, H., Taira, T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Toxicol. Sci. 88
  
  Pages: 114-126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Induction of reactive oxygen species by bisphenol A and abrogation of bisphenol A-induced cell injury by DJ-1.2005
- Author(s)
  Ooe, H., Taira, T., Iguchi-Ariga, S.M.M., Ariga, H
- Journal Title
  
  Toxicol.Sci. 88
  
  Pages: 114-126
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] DJ-1 restores p53 transcription activity inhibited by Topors/p53BP32005
- Author(s)
  Sekito A., Taira, T., Niki, T., Iguchi-Ariga, S.M.M., Ariga, H
- Journal Title
  
  Int.J.Oncol. 26
  
  Pages: 641-648
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Expression profiles of genes in DJ-1-knockdown and L166P DJ-1 mutant cells.2005
- Author(s)
  Nishinaga, H., Takahashi-Niki, K., Taira, T., Andreadis, A., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Neuroscience Lett. 390
  
  Pages: 54-59
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Stimulation of transforming activity of DJ-1 by Abstrakt, a DJ-1-binding protein.2005
- Author(s)
  Sekito A., Taira, T., Niki, T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Int. J. Oncol. 26
  
  Pages: 685-689
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress2005
- Author(s)
  Li, H.M., Niki, T., Taira T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Free Radic.Res. 39
  
  Pages: 1091-1099
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress.2005
- Author(s)
  Li, H.M., Niki, T., Taira, T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Free Radic. Res. 39
  
  Pages: 1091-1099
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] Structure and characterization of AAT-1 isoforms2005
- Author(s)
  Matsuda, E., Ishizaki, R., Taira, T., Iguchi-Ariga, S.M.M., Ariga, H.
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 898-901
- NAID
  120005350119
- Data Source
  KAKENHI-PROJECT-17590049
[Journal Article] DJ-1 plays a role in anti-oxidative stress to prevent cell death2004
- Author(s)
  Taira, T. et al.
- Journal Title
  
  EMBO Rep. 5
  
  Pages: 213-218
- Data Source
  KAKENHI-PROJECT-16015202
[Journal Article] Co-localization with DJ-1 is essential for the androgen receptor to exert its transcription activity that has been impaired by androgen-antagonists2004
- Author(s)
  Taira, T. et al.
- Journal Title
  
  Biol. Pharm. Bull. 27
  
  Pages: 574-577
- NAID
  110003608809
- Data Source
  KAKENHI-PROJECT-16015202
[Journal Article] DJ-1 plays a role in anti-oxidative stress to prevent cell death.2004
- Author(s)
  Taira, T.et al.
- Journal Title
  
  EMBO Rep. 5
  
  Pages: 213-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390248
[Journal Article] Co-localization with DJ-1 is essential for the androgen receptor to exert its transcription activity that has been impaired by androgen-antagonists2004
- Author(s)
  Taira, T.et al.
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 574-577
- NAID
  110003608809
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590053
[Journal Article] Co-localization with DJ-1 is essential for the androgen receptor to exert its transcription activity that has been impaired by androgen-antagonists2004
- Author(s)
  Taira, T. et al.
- Journal Title
  
  Biol. Pharm. Bull. 27
  
  Pages: 574-577
- NAID
  110003608809
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390248
[Journal Article] DJ-1 plays a role in anti-oxidative stress to prevent cell death2004
- Author(s)
  Taira, T.et al.
- Journal Title
  
  EMBO Rep. 5
  
  Pages: 213-218
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590053
[Journal Article] DJ-1 plays a role in anti-oxidative stress to prevent cell death.2004
- Author(s)
  Taira, T. et al.
- Journal Title
  
  EMBO Rep. 5
  
  Pages: 213-218
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590053
[Journal Article] DJ-1 plays a role in anti-oxidative stress to prevent cell death2004
- Author(s)
  Taira, T.et al.
- Journal Title
  
  EMBO Rep. 5
  
  Pages: 213-218
- Data Source
  KAKENHI-PROJECT-16390248
[Journal Article] DJ-1 plays a role in anti-oxidative stress to prevent cell death2004
- Author(s)
  Taira, T. et al.
- Journal Title
  
  EMBO Rep. 5
  
  Pages: 213-218
- Data Source
  KAKENHI-PROJECT-15590053
[Journal Article] DJ-1 plays a role in anti-oxidative stress to prevent cell death2004
- Author(s)
  Taira, T. et al.
- Journal Title
  
  EMBO Rep. 5
  
  Pages: 213-218
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390248
[Journal Article] Co-localization with DJ-1 is essential for the androgen receptor to exert its transcription activity that has been impaired by androgen-antagonists2004
- Author(s)
  Taira, T.et al.
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 574-577
- NAID
  110003608809
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390248
[Journal Article] Co-localization with DJ-1 is essential for the androgen receptor to exert its transcription activity that has been impaired by androgen-antagonists2004
- Author(s)
  Taira, T. et al.
- Journal Title
  
  Biol.Pharm.Bull. 27
  
  Pages: 574-577
- NAID
  110003608809
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590053
[Presentation] 家族性パーキンソン病(PARK7)原因遺伝子産物DJ-1タンパク質の生物種差2011
- Author(s)
  平敬宏
- Organizer
  第13回応用薬理シンポジウム
- Place of Presentation
  船橋市民創造館きららホール(千葉県船橋市)(招待講演)
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21590091
[Presentation] 家族性パーキンソン病(PARK7)原因遺伝子産物DJ-1タンパク質の生物種差2011
- Author(s)
  平敬宏
- Organizer
  第13回応用薬理シンポジウム
- Place of Presentation
  船橋市
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21590091
[Presentation] Identification of MeCP2-targetsynaptic molecules associated with pathogenesis of Rett syndrome2010
- Author(s)
  Kunio Miyake, Takae Hirasawa, Masaki soutome, Masayuki, Itoh, Yu-ichi Goto, Kazushi Endoh, Shinichi Kudou, Sana Yokoi, Takahiro Taira, Johji Inazawa, Takeo Kubota
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21590091
[Presentation] ヒトDJ-1特異的なチロシン水酸化酵素遺伝子の転写活性化調節2010
- Author(s)
  石川静麻,平敬宏,仁木加寿子,仁木剛史,有賀寛芳,有賀早苗
- Organizer
  第33回日本神経科学大会・第53回日本神経化学会大会第20回日本神経回路学会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21590091
[Presentation] がんウイルスによるアポトーシス制御因子p32/HABP1/gC1qRの機能阻害2010
- Author(s)
  鈴木千恵,手石方康弘,笹島仁,横澤英吉,平敬宏,藤室雅弘
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-21590091
[Presentation] 家族性パーキンソン病(PARK7)原因遺伝子産物DJ-1タンパク質の機能と今後の研究課題2010
- Author(s)
  平敬宏
- Organizer
  第17回順天堂大学神経学セミナー
- Place of Presentation
  東京都文京区
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590091
[Presentation] Inhibition of PTEN phosphatase activity by the direct interaction of DJ-1 with PTEN under the oxidative conditions2009
- Author(s)
  金允哲,北浦廣剛,平敬宏,有賀早苗,有賀寛芳
- Organizer
  第32回日本神経科学会大会
- Place of Presentation
  名古屋市
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-21590091
[Presentation] Human DJ-1-dependent activation of dopamine biosynthesis through interction of tyrosine hydroxylase with DJ-12009
- Author(s)
  石川静麻,平敬宏,有賀寛芳,有賀早苗
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-21590091

1. ARIGA Sanae (90184283)

# of Collaborated Projects: 13 results

# of Collaborated Products: 3 results
2. ARIGA Hiroyoshi (20143505)

# of Collaborated Projects: 13 results

# of Collaborated Products: 3 results
3. KITAURA Hirotake (10281817)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
4. OHGA Rie (00160432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. FUJIMURO Masahiro (20360927)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 加藤宏幸 (60185866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 松本健一 (30202328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松田正 (20212219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 奈良敏文 (30241350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAIRA Takahiro 平 敬宏

TAKRA Takahiro.Y. 平 敬宏

Research Projects

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Co-Researchers

Effect of respiratory disease onset and functionality in the alveolar-bronchial of oxidative stress defense protein DJ-1Principal Investigator

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Study on transcriptional activation mechanism of DJ-1 gene(PARK7) and the trial to Parkinson's disease cure developmentPrincipal Investigator

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Functional analysis of DJ-1, a causative gene product for familial Parkinson's diseasePrincipal Investigator

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Function of MM-1, a novel c-Myc-binding protein, as a tumor suppressorPrincipal Investigator

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TAIRA Takahiro 平敬宏

TAKRA Takahiro.Y. 平敬宏