Hotta Harumi 堀田晴美

… Alternative Names

HOTTA Harumi 堀田晴美

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Researcher Number	70199511
Other IDs	https://orcid.org/0000-0002-4590-7162
External Links
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長
Affiliation (based on the past Project Information) *help	2017 – 2024: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 2012 – 2014: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究副部長 2005: Tokyo Metropolitan Institute of Gerontology, Senior Researcher, 東京都老人総合研究所, 主任研究員 2004: 財団法人東京都高齢者研究, 福祉振興財団・東京都老人総合研究所, 主任研究員 2003: TOKYO METROPOLITAN FOUNDATION FOR RESEARCH ON AGING AND PROMOTION OF HUMAN WELFARE, TOKYO METROPOLITAN INSTITUTE OF GERONTOLOGY, MOTOR AND AUTONOMIC NERVOUS SYSTEM INTEGRATION RESEARCH GROUP, SENIOR RESEARCHER, 東京都老人総合研究所・運動・自律機能相関研究グループ, 主任研究員 … More 2002: 東京都老人総合研究所, 運動・自律機能相関研究グループ, 研究員(主任) 2000 – 2001: (財)東京都老人総合研究所, 研究員(主任) 1999: 財団法人東京都老人総合研究所, 自律神経部門, 研究員(主任) 1998: (財)東京都老人総合研究所, 自律神経部門, 研究員 1997: (財)東京都老人総合研究所, 自律神経部門, 研究員(主任) 1996: (財)東京都老人総合研究所, 自律神経部門, 主任研究員 1996: 東京都老人総合研究所, 自律神経部門, 主任研究員 1995: Tokyo Metropoliten Institute of Gerontology Dept.Auton.Nerv.Syst., researcher, 自律神経部門, 研究員 1993 – 1995: (財)東京都老人総合研究所, 自律神経部門, 研究員 Less
Review Section/Research Field	Principal Investigator Environmental physiology (including Physical medicine and Nutritional physiology) / Basic Section 59010:Rehabilitation science-related / Rehabilitation science/Welfare engineering / Environmental physiology (including Physical medicine and Nutritional physiology) / Rehabilitation science/Welfare engineering Except Principal Investigator 神経・脳内生理学
Keywords	Principal Investigator ラット / 大脳皮質 / 老化 / 電気刺激 / 自律神経 / 脳局所血流 / 交感神経 / 嚥下 / 機械的刺激 / 咽頭 … More / ELISA / BDNF / 前脳基底部 / マイネルト核 / 一過性虚血 / 遅発性神経細胞死 / 海馬 / サルコペニア / 筋血流 / 血流 / 腰部交感神経 / サルコぺニア / 筋血管 / 筋収縮 / 張力 / 収縮力 / 反射 / 筋収縮力 / 圧受容器 / 大動脈 / 神経筋接合部 / 筋緊張 / 筋力 / 骨格筋 / フレイル / 甲状腺ホルモン / 求心性神経 / ホルモン分泌 / 嚥下反射 / 副交感神経 / カルシトニン / サイロキシン / 上喉頭神経 / 甲状腺 / rat / electrical stimulation / cerebral cortex / basal forebrain / 細胞外液 / TRANSIENT CEREBRAL ISCHEMIA / DELAYED NEURONAL DEATH / NUCLEUS BASALIS OF MEYNERT / REGIONAL CEREBRAL BLOOD FLOW / RAT / HIPPOCAMPUS / CEREBRAL CORTEX / BASAL FOREBRAIN / 中隔野 / 一過性脳虚血 / 神経活動 / 神経刺激 / 脳機能 / 運動 / 脳活動 / アセチルコリン / 咀嚼 / セントラルコマンド / コリン作動系 / 脳血流 / 咀嚼運動 / ニコチン性受容体 / 無髄線維 / 有髄線維 / 神経伝導速度 / 排尿機能 / 膀胱 / 体性感覚 / 伝導速度 / 骨盤神経 / 排尿 / 眼底血流 … More Except Principal Investigator 脳血流 / conscious animals / nerotransmitter / cerebral blood flow / 意識下動物 / 神経伝達物質 / somatic stimulation / splenic blood flow / splenic sympathetic nerve / natural kiler cell / 体性感覚刺激 / 脾臓血流 / 脾臓交感神経 / NK活性 / 脳血流の神経性調節 / デジタルマイクロスコープ / ラット / 血管径 / 頭窓法 / 脳血管 Less

嚥下にともなう自律神経の活性化が骨格筋におよぼす作用とサルコペニア予防への応用Principal Investigator
- Principal Investigator
  
  堀田晴美
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Studies on mechanism of hormonal secretion from thyroid gland associated with swallowing for possible application to frail preventionPrincipal Investigator
- Principal Investigator
  
  Hotta Harumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Neural mechanisms of the effects of masticatory activity on cerebral functionsPrincipal Investigator
- Principal Investigator
  
  HOTTA Harumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Effect of stimulation of the nucleus basalis of Meynert on BDNF in the cerebral cortex.Principal Investigator
- Principal Investigator
  
  HOTTA Harumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
EFFECTS OF ACTIVATING THE CHOLINERGIC VASODILATIVE SYSTEM ORIGINATING IN THE BASAL FOREBRAIN ON BLOOD FLOW AND DELAYED NEURONAL DEATH FOLLOWING TRANSIENT ISCHEMIAPrincipal Investigator
- Principal Investigator
  
  HOTTA Harumi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
ニコチン性アセチルコリン受容体による虚血性神経細胞死と脳微小血管の制御Principal Investigator
- Principal Investigator
  
  堀田晴美
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
老化ラットにおける排尿機能の神経性調節Principal Investigator
- Principal Investigator
  
  堀田晴美
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
意識下動物における脳の微細血管の直視下連続的観察法の開発Principal Investigator
- Principal Investigator
  
  堀田晴美, SATO Akio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
老化ラットにおける脳局所血流とその自律神経性調節Principal Investigator
- Principal Investigator
  
  堀田晴美
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
老化ラットにおける眼底血流とその自律神経性調節Principal Investigator
- Principal Investigator
  
  堀田晴美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
A development of a new method for continuous measurement of regional cerebral blood flow and analysis of the regulation of cerebral blood flow in a conscious rat.
- Principal Investigator
  
  SATO Akio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Tokyo Metropolitan Institute of Gerontology (TMIG)
Elucidation of the autonomic nervous control of immune organs.
- Principal Investigator
  
  SATO Akio
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Tokyo Metropolitan Institute of Gerontology (TMIG)

[Book] 人体の構造と機能及び疾患．５章加齢と疾患2024
- Author(s)
  堀田晴美、渡辺信博
- Total Pages
  214
- Publisher
  医歯薬出版
- ISBN
  9784263266724
- Data Source
  KAKENHI-PROJECT-23K20363
[Book] 脳循環賦活の基礎.老年医学update 2006-072006
- Author(s)
  堀田晴美
- Publisher
  メジカルビュー社,東京,
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Insulin resistance induces earlier initiation of cognitive dysfunction mediated by cholinergic deregulation in a mouse model of Alzheimer’s disease.2023
- Author(s)
  Izuo, N., Watanabe, N., Noda, Y., Saito, T., Saido, T.C., Yokote, K., Hotta, H., Shimizu, T.
- Journal Title
  
  Aging Cell
  
  Volume: 22 Issue: 11 Pages: 1-13
- DOI
  10.1111/acel.13994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19607, KAKENHI-PROJECT-23K07007, KAKENHI-PROJECT-23K20363
[Journal Article] Effects of gentle mechanical skin stimulation on subjective symptoms and joint range of motions in people with chronic neck and shoulder discomfort2023
- Author(s)
  Watanabe Nobuhiro、Nara Marina、Suzuki Shihoko、Sugie Masamitsu、Yamamoto Takao、Hotta Harumi
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 73 Issue: 1 Pages: 1-11
- DOI
  10.1186/s12576-023-00862-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K20363
[Journal Article] Sympathetic modulation of hindlimb muscle contractility is altered in aged rats2023
- Author(s)
  Hotta Harumi、Iimura Kaori、Watanabe Nobuhiro、Suzuki Harue、Sugie Masamitsu、Shigemoto Kazuhiro
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-023-33821-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K20363
[Journal Article] Mild thermal stimulation of the buttock skin increases urinary voiding efficiency in anesthetized rats2022
- Author(s)
  Iimura Kaori、Watanabe Nobuhiro、Hotta Harumi
- Journal Title
  
  Autonomic Neuroscience
  
  Volume: 242 Pages: 103022-103022
- DOI
  10.1016/j.autneu.2022.103022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K20363
[Journal Article] Attenuation of widespread hypersensitivity to noxious mechanical stimuli by inhibition of GABAergic neurons of the right amygdala in a rat model of chronic back pain2022
- Author(s)
  Tokunaga Ryota、Takahashi Yukari、Touj Sara、Hotta Harumi、Leblond Hugues、Kato Fusao、Piche Mathieu
- Journal Title
  
  European Journal of Pain
  
  Volume: 26 Issue: 4 Pages: 911-928
- DOI
  10.1002/ejp.1921
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K23010, KAKENHI-PROJECT-21H02816, KAKENHI-PROJECT-20K09207, KAKENHI-PROJECT-23K20363
[Journal Article] Maintenance of contractile force of the hind limb muscles by the somato-lumbar sympathetic reflexes.2021
- Author(s)
  Harumi Hotta, Kaori Iimura, Nobuhiro Watanabe, Kazuhiro Shigemoto
- Journal Title
  
  The journal of physiological sciences
  
  Volume: 71 Issue: 1 Pages: 1-13
- DOI
  10.1186/s12576-021-00799-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04064, KAKENHI-PROJECT-23K20363
[Journal Article] Influence of Intragastric Administration of Traditional Japanese Medicine, Ninjin’Yoeito, on Cerebral Blood Flow via Muscarinic Acetylcholine Receptors2021
- Author(s)
  Watanabe Nobuhiro、Iimura Kaori、Hotta Harumi
- Journal Title
  
  Evidence-Based Complementary and Alternative Medicine
  
  Volume: 2021 Pages: 1-10
- DOI
  10.1155/2021/9930023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K20363
[Journal Article] Chronic Electrical Stimulation of the Superior Laryngeal Nerve in the Rat: A Potential Therapeutic Approach for Postmenopausal Osteoporosis2020
- Author(s)
  Iimura Kaori、Watanabe Nobuhiro、Milliken Philip、Hsieh Yee-Hsee、Lewis Stephen J.、Sridhar Arun、Hotta Harumi
- Journal Title
  
  Biomedicines
  
  Volume: 8 Issue: 9 Pages: 369-369
- DOI
  10.3390/biomedicines8090369
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K20363
[Journal Article] Mechanism of vasodilation in the cerebral cortex induced by stimulation of the cortical masticatory area2020
- Author(s)
  堀田晴美、鈴木はる江、井上富雄
- Journal Title
  
  The Autonomic Nervous System
  
  Volume: 57 Issue: 4 Pages: 206-211
- DOI
  10.32272/ans.57.4_206
- NAID
  130007973235
- ISSN
  0288-9250, 2434-7035
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K20363
[Journal Article] 咽頭への刺激によって起こる甲状腺からのホルモン分泌とその神経性メカニズム2020
- Author(s)
  飯村佳織, 渡辺信博, 鈴木はる江,堀田晴美
- Journal Title
  
  脳神経内科
  
  Volume: 93 Pages: 329-335
- Data Source
  KAKENHI-PROJECT-23K20363
[Journal Article] 咽頭への刺激によって起こる甲状腺からのホルモン分泌とその神経性メカニズム2020
- Author(s)
  飯村佳織、渡辺信博、鈴木はる江、堀田晴美
- Journal Title
  
  脳神経内科（神経内科）
  
  Volume: ー
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Cerebral artery dilation during transient ischemia is impaired by mechanical barrier of amyloid β deposition around cerebral artery in Alzheimer’s disease model mice2020
- Author(s)
  Watanabe, N., Noda, Y., Iimura, K., Shimizu, T., Hotta, H.
- Journal Title
  
  J. Physiol. Sci.
  
  Volume: 70 Issue: 1 Pages: 57-57
- DOI
  10.1186/s12576-020-00785-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03583, KAKENHI-PROJECT-23K20363
[Journal Article] Gentle Perineal Skin Stimulation for Control of Nocturia2019
- Author(s)
  Hotta Harumi、Watanabe Nobuhiro
- Journal Title
  
  The Anatomical Record
  
  Volume: 302 Issue: 10 Pages: 1824-1836
- DOI
  10.1002/ar.24135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Involvement of the basal nucleus of Meynert on regional cerebral cortical vasodilation associated with masticatory muscle activity in rats.2019
- Author(s)
  Hotta H, Suzuki H, Inoue T, Stewart M.
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: in press Issue: 12 Pages: 2416-2428
- DOI
  10.1177/0271678x19895244
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22726, KAKENHI-PROJECT-17H04373, KAKENHI-PROJECT-17K01550, KAKENHI-PROJECT-23K20363
[Journal Article] Regulation of thyroid function by autonomic reflex2019
- Author(s)
  堀田晴美、飯村佳織、鈴木はる江
- Journal Title
  
  The Autonomic Nervous System
  
  Volume: 56 Issue: 3 Pages: 132-137
- DOI
  10.32272/ans.56.3_132
- NAID
  130007718940
- ISSN
  0288-9250, 2434-7035
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Central nervous system mechanisms involved in inhibition of micturition reflex by gentle mechanical skin stimulation2019
- Author(s)
  堀田晴美
- Journal Title
  
  The Autonomic Nervous System
  
  Volume: 56 Issue: 1 Pages: 46-53
- DOI
  10.32272/ans.56.1_046
- NAID
  130007634995
- ISSN
  0288-9250, 2434-7035
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Thyroxin and calcitonin secretion into thyroid venous blood is regulated by pharyngeal mechanical stimulation in anesthetized rats2019
- Author(s)
  Iimura Kaori、Suzuki Harue、Hotta Harumi
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 69 Issue: 5 Pages: 749-756
- DOI
  10.1007/s12576-019-00691-8
- NAID
  40022006465
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Age-Related Changes in Neuromodulatory Control of Bladder Micturition Contractions Originating in the Skin2018
- Author(s)
  Hotta Harumi、Suzuki Harue、Iimura Kaori、Watanabe Nobuhiro
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 12 Pages: 1-11
- DOI
  10.3389/fnins.2018.00117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] 高齢者における疼痛コントロール：感覚情報伝達調節と老化.2018
- Author(s)
  堀田晴美
- Journal Title
  
  基礎老化研究
  
  Volume: 42 Pages: 37-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Age-related changes in function and gene expression of the male and female mouse bladder2018
- Author(s)
  Kamei Jun、Ito Hiroki、Aizawa Naoki、Hotta Harumi、Kojima Toshio、Fujita Yasunori、Ito Masafumi、Homma Yukio、Igawa Yasuhiko
- Journal Title
  
  Sci Rep
  
  Volume: 8(1) Issue: 1 Pages: 2089-2089
- DOI
  10.1038/s41598-018-20406-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11039, KAKENHI-PROJECT-17K11174, KAKENHI-PROJECT-17K01550, KAKENHI-PROJECT-17H06638
[Journal Article] 加齢により特定タイプの皮膚神経活動が低下することで，膀胱の収縮が抑制されにくくなる．2018
- Author(s)
  堀田晴美、鈴木はる江、飯村佳織、渡辺信博
- Journal Title
  
  自律神経
  
  Volume: 55 Pages: 237-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Vascular Gap Junctions Contribute to Forepaw Stimulation-Induced Vasodilation Differentially in the Pial and Penetrating Arteries in Isoflurane-Anesthetized Rats2018
- Author(s)
  Watanabe Nobuhiro、Sasaki Satoshi、Masamoto Kazuto、Hotta Harumi
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 11 Pages: 446-446
- DOI
  10.3389/fnmol.2018.00446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Modulation of Calcitonin, Parathyroid Hormone, and Thyroid Hormone Secretion by Electrical Stimulation of Sympathetic and Parasympathetic Nerves in Anesthetized Rats2017
- Author(s)
  Hotta Harumi、Onda Akiko、Suzuki Harue、Milliken Philip、Sridhar Arun
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 11 Pages: 1-9
- DOI
  10.3389/fnins.2017.00375
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01550
[Journal Article] Types of skin afferent fibers and spinal opioid receptors that contribute to touch-induced inhibition of heart rate changes evoked by noxious cutaneous heat stimulation2015
- Author(s)
  Nobuhiro Watanabe, Mathieu Piche, Harumi Hotta
- Journal Title
  
  Mol Pain
  
  Volume: 11 Pages: 4-4
- DOI
  10.1186/s12990-015-0001-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500635
[Journal Article] Regulation of gastric motility and blood flow during acute nociceptive stimulation of the paraspinal muscles in urethane-anesthetised rats.2014
- Author(s)
  Piché M, Watanabe N, Hotta H
- Journal Title
  
  J Physiol Sci
  
  Volume: 64 Issue: 1 Pages: 37-46
- DOI
  10.1007/s12576-013-0288-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02219, KAKENHI-PROJECT-24500635
[Journal Article] Non-noxious skin stimulation activates the nucleus basalis of Meynert and promotes NGF secretion in the parietal cortex via nicotinic ACh receptors.2014
- Author(s)
  Hotta H, Watanabe N, Piché M, Hara S, Yokawa T, Uchida S
- Journal Title
  
  SJ Physiol Sci
  
  Volume: 64 Issue: 4 Pages: 253-260
- DOI
  10.1007/s12576-014-0313-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12F02219, KAKENHI-PROJECT-24500635
[Journal Article] Basal μ-opioid receptor availability in the amygdala predicts the inhibition of pain-related brain activity during heterotopic noxious counter-stimulation.2014
- Author(s)
  Piché M, Watanabe N, Sakata M, Oda K, Toyohara J, Ishii K, Ishiwata K, Hotta H
- Journal Title
  
  Neurosci Res
  
  Volume: 81-82 Pages: 78-84
- DOI
  10.1016/j.neures.2014.02.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02219, KAKENHI-PROJECT-24500635
[Journal Article] The missing link between long-term stimulation of nicotinic receptors and the increases of acetylcholine release and vasodilation in the cerebral cortex of aged rats.2013
- Author(s)
  Uchida S, Hotta H, Misawa H, Kawashima K
- Journal Title
  
  J Physiol Sci
  
  Volume: 63 Issue: 2 Pages: 95-101
- DOI
  10.1007/s12576-012-0239-2
- NAID
  10031169593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500635, KAKENHI-PROJECT-24590308
[Journal Article] Differential human brain activity induced by two perceptually indistinguishable gentle cutaneous stimuli2013
- Author(s)
  Watanabe N, Ishii K, Hotta H, Oda K, Sakata M, Toyohara J, Ishiwata K
- Journal Title
  
  NeuroReport
  
  Volume: 24 Issue: 8 Pages: 425-430
- DOI
  10.1097/wnr.0b013e32836164d4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500635
[Journal Article] Layer-specific dilation of penetrating arteries induced by stimulation of the nucleus basalis of Meynert in the mouse frontal cortex.2013
- Author(s)
  Hotta, H., Masamoto,K., Uchida,S.,Sekiguchi,Y., Takuwa,H., Kawaguchi,H., Shigemoto,K., Sudo,R., Tanishita,K., Ito,H. and Kanno,I.
- Journal Title
  
  J Cereb Blood Flow Metab.
  
  Volume: 9 Issue: 9 Pages: 1440-7
- DOI
  10.1038/jcbfm.2013.92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390228, KAKENHI-PROJECT-24500635, KAKENHI-PROJECT-24659578, KAKENHI-PROJECT-25670437
[Journal Article] A gentle mechanical skin stimulation technique for inhibition of micturition contractions of the urinary bladder.2012
- Author(s)
  Hotta H, Masunaga K, Miyazaki S, Watanabe N, Kasuya Y
- Journal Title
  
  Auton Neurosci
  
  Volume: 167 Issue: 1-2 Pages: 12-20
- DOI
  10.1016/j.autneu.2011.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500635
[Journal Article] Effect of gentle cutaneous stimulation on heat-induced autonomic response and subjective pain intensity in healthy humans.2012
- Author(s)
  Watanabe N, Miyazaki S, Mukaino Y, Hotta H
- Journal Title
  
  J Physiol Sci
  
  Volume: 62 Issue: 4 Pages: 343-350
- DOI
  10.1007/s12576-012-0210-2
- NAID
  10030810001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500635
[Journal Article] Responses of Acetylcholine release and redional blood flow in the hippocampus during walking in aged rats.2006
- Author(s)
  Uchida, S., Suzuki, A., Kagitani, F, Hotta
- Journal Title
  
  Journal of Physiological Sciences 印刷中
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Effects of nicotine on regional blood flow in the olfactory bulb in rats.2006
- Author(s)
  Shiba, K., Machida, T., Uchida, S., Hotta, H.
- Journal Title
  
  European Journal of Pharmacology 印刷中
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Cyclic phosphatidic acid stimulates respiration without producing vasopressor or tachycardiac effects in raats.2006
- Author(s)
  Hotta, H., Kagitani, F., Murakami-Murofushi, K.
- Journal Title
  
  European Journal of Pharmacology 印刷中
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Cerebral regional cortical blood flow response during joint stimulation in cats.2005
- Author(s)
  Hotta, H., Sato, A., Schmidt, R.F, Suzuki, A.
- Journal Title
  
  Neuroreport 16(15)
  
  Pages: 1693-1695
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Manual acupuncture needle stimulation of the rat hindlimb activates groups I,II,III and IV single afferent nerve fibers in the dorsal apinal roots.2005
- Author(s)
  Kagitani F, Uchida S, Hotta H, Aikawa Y.
- Journal Title
  
  Japanese Journal of Physiology 55・3
  
  Pages: 149-155
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] 長期的な自発性運動がラット歩行中の海馬局所血流と細胞外アセチルコリン放出の増加反応に及ぼす影響2005
- Author(s)
  内田さえ, 小島成実, 野本恵美, 野本刺激, 金井千恵子, 堀田晴美
- Journal Title
  
  基礎老化研究 29・3
  
  Pages: 25-30
- NAID
  10027835496
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Effects of long-term voluntary exercise on the responses of regional blood flow and extracellular acetylcholine in the hippocampus during walking in adult rats.2005
- Author(s)
  Uchida, S., Kojima, N., Nomoto, E., Nomoto, S., Hotta, H.
- Journal Title
  
  Biomadical Gerontology 29(3)
  
  Pages: 25-30
- NAID
  10027835496
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Manual acupuncture needle stimulation of the rat hindlimb activates groups I, II, III and IV single afferent nerve fibers in the dorsal spinal roots.2005
- Author(s)
  Kagitani F, Uchida S, Hotta H, Aikawa Y.
- Journal Title
  
  Japanese Journal of Physiology 55・3
  
  Pages: 149-155
- NAID
  10016882377
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Cutaneous mechanical stimulation regulates ovarian blood flow via activation of spinal and supraspinal reflex pathways in anesthetized rats.2005
- Author(s)
  Uchida, S., Kagitani, F., Hotta, H., Hanada, T, Aikawa, Y.
- Journal Title
  
  Japanese Journal of Physiology 55(5)
  
  Pages: 265-277
- NAID
  10018623909
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Cutaneous mechanical stimulation regulates ovarian blood flow via activation of spinal and supraspinal reflex pathways in anesthetized rats.2005
- Author(s)
  Uchida, S., Kagitani, F., Hotta, _H., Hanada, T., Aikawa, Y.
- Journal Title
  
  Japanese Journal of Physiology 55・5
  
  Pages: 265-277
- NAID
  10018623909
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Manual acupuncture needle stimulation of the rat hindlimb activates groups I, II, III and IV single afferent nerve fibers in the dorsal spinal roots.2005
- Author(s)
  Kagitani, F., Hotta, H., Uchida, S, Aikawa, Y.
- Journal Title
  
  Japanese Journal of Physiology. 55(3)
  
  Pages: 149-155
- NAID
  10016882377
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Cutaneous mechanical stimulation regulates ovarian blood flow via activation of spinal and supraspinal reflex pathways in anesthetized rats.2005
- Author(s)
  Uchida, S., Kagitani, F., Hotta, H., Handa, T., Aikawa, Y.
- Journal Title
  
  Japanese Journal of Physiology 55・5
  
  Pages: 265-277
- NAID
  10018623909
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Cerebral regional cortical blood flow response during joint stimulation in cats.2005
- Author(s)
  Hotta H, Sato A, Schmidt RF, Suzuki A.
- Journal Title
  
  Neuroreport 16・5
  
  Pages: 1693-1695
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] The effects of aging on somatocardiac reflexes in anesthetized rats.2004
- Author(s)
  Suzuki A, Uchida S, Hotta H.
- Journal Title
  
  Japanese Journal of Physiology 54・2
  
  Pages: 137-141
- NAID
  80016680303
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Stimulation of the nucleus basalis of Meynert increases diameter of the parenchymal blood vessels in the rat cerebral cortex.2004
- Author(s)
  Hotta H, Kanai S, Uchida S, Kanda K.
- Journal Title
  
  Neuroscience Letters 358・2
  
  Pages: 103-106
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Cyclic phosphatidic acid stimulates respiration without producing vasopressor or tachycardiac effects in rats.
- Author(s)
  Hotta, H., Kagitani, F, Murakami-Murofushi, K.
- Journal Title
  
  European Journal of Pharmacology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Effects of nicotine on regional blood flow in the olfactory bulb in rats.
- Author(s)
  Shiba, K., Machida, T., Uchida, S, Hotta.H.
- Journal Title
  
  European Journal of Pharmacology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Journal Article] Responses of acetylcholine release and regional blood flow in the hippocampus during walking in aged rats.
- Author(s)
  Uchida, S., Suzuki, A., Kagitani, F, Hotta, H.
- Journal Title
  
  Journal of Physiological Sciences (in press)
- NAID
  10020331723
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590187
[Presentation] Dysregulation of the Autonomic Nervous System with Aging - An Approach from the Interaction with the Somatic Nervous System.2024
- Author(s)
  Hotta H.
- Organizer
  第101回日本生理学会大会，北九州, 2024.3.28-30.
- Invited
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] Sympathetic modulation of hindlimb muscle contractility in young and aged rats.2023
- Author(s)
  Hotta H, Watanabe N, Suzuki H.
- Organizer
  The International Association of Geriatrics and Gerontology (IAGG)/Asia-Oceania regional congress 2023, Yokohama, 2023.6.12-14.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] Somato-autonomic reflex possibly related to the skeletal muscle homeostasis.2023
- Author(s)
  Hotta H.
- Organizer
  International Scientific Acupuncture and Medicine Sy6-8.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] Sympathetic modulation of skeletal muscle contractility is altered by age and sex.2023
- Author(s)
  堀田晴美, 飯村佳織, 渡辺信博, 鈴木はる江.
- Organizer
  第100回日本生理学会，京都, 2023.3.14-16.
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] 老齢ラットにおける後肢筋収縮力の交感神経性調節の変化.2023
- Author(s)
  杉江正光, 渡辺信博, 鈴木はる江, 堀田晴美.
- Organizer
  第76回日本自律神経学会総会，さいたま，2023.10.28-29.
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] Sympathetic regulation of skeletal muscle contractile force decreases with muscle atrophy in aged rats2022
- Author(s)
  Hotta H, Iimura K, Watanabe N, Suzuki H, Shigemoto K
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] The somato-lumbar sympathetic nerve reflexes induced by tetanic contractions of the fast-contracting hindlimb muscles help to maintain its contractile force2021
- Author(s)
  Hotta H, Iimura K, Watanabe N, Shigemoto K
- Organizer
  第98回日本生理学会大会（第126回日本解剖学会総会・全国学術集会との合同学会）
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] 自律神経系による骨と筋のホメオスタシス2021
- Author(s)
  堀田晴美
- Organizer
  第8回日本サルコペニア・フレイル学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] Neural regulation of cerebral microvasculature, and its association with mastication2021
- Author(s)
  Hotta H
- Organizer
  第46回日本微小循環学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] 骨格筋の恒常性維持における自律神経の役割と老化2021
- Author(s)
  堀田晴美
- Organizer
  第74回日本自律神経学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] Effects of pharyngeal mechanical stimulation on skeletal muscle blood flow and blood pressure.2020
- Author(s)
  Tanaka Y, Watanabe N, Suzuki H, Fukui K, Hotta H
- Organizer
  第97回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] Activation of the basal nucleus of Meynert and cortical vasodilation associated with cortically-induced mastication in rats2020
- Author(s)
  Hotta H, Suzuki H, Inoue T, Stewart M
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] Involvement of the basal nucleus of Meynert on cerebral cortical vasodilation associated with mastication in rats2020
- Author(s)
  Hotta H, Suzuki H, Inoue T, Stewart M
- Organizer
  日本基礎老化学会第43回大会
- Data Source
  KAKENHI-PROJECT-23K20363
[Presentation] The modulation of thyroid functions by sensory input from pharynx.2020
- Author(s)
  Hotta H, Iimura K, Suzuki H
- Organizer
  第97回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] Pharyngeal stimulation promotes secretion of thy-roxin and calcitonin, via thyroid parasympathetic nerve reflex.2019
- Author(s)
  Iimura K, Hotta H. Suzuki H
- Organizer
  ISAN 2019, Los Angeles, California
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 「食べる」ことの重要性―生理学研究でわかった新知見．2019
- Author(s)
  堀田晴美
- Organizer
  第31回日本老年学会総会合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] ラット咀嚼筋活動に伴う大脳皮質局所血流増加反応に対するマイネルト基底核の関与．2019
- Author(s)
  堀田晴美, 鈴木はる江, 井上富雄, Mark Stewart
- Organizer
  第72回日本自律神経学会総会
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 咽頭への機械的刺激は上喉頭神経を介し代謝調節ホルモンのサイロキシンとカルシトニンの分泌を促進する．2019
- Author(s)
  飯村佳織、鈴木はる江、堀田晴美
- Organizer
  日本基礎老化学会第42回大会
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 咽頭の機械的刺激による甲状腺ホルモンとカルシトニン分泌の促進．2019
- Author(s)
  堀田晴美
- Organizer
  首都大学バイオコンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 歩行・咀嚼・嚥下は、なぜ脳やからだの健康に大切なのか？2019
- Author(s)
  堀田晴美
- Organizer
  第37回都市高齢者の健康長寿医療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 麻酔下ラットにおける咽頭部への機械的刺激は甲状腺からのサイロキシンおよびカルシトニン分泌を促進する.2018
- Author(s)
  飯村佳織, 遠田明子, 鈴木はる江, 堀田晴美
- Organizer
  第71回日本自律神経学会総会, 埼玉, 2018. 10. 25-26
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] Thyroxine secretion from the thyroid gland is promoted by non-noxious mechanical stimulation of the pharyngeal mucosa in anesthetized rats.2018
- Author(s)
  飯村佳織, 遠田明子, 鈴木はる江, 堀田晴美
- Organizer
  第41回日本神経科学大会, 神戸, 2018. 7. 26-29
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 自律神経反射による甲状腺機能の調節自律. シンポジウム「痛みと情動・自律反応」2018
- Author(s)
  堀田晴美
- Organizer
  第71回日本自律神経学会総会, 埼玉, 2018. 10. 25-26
- Invited
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 甲状腺からのサイロキシン（T4）分泌は、麻酔下ラットにおける咽頭への触刺激によって促進される2018
- Author(s)
  飯村佳織, 遠田明子, 鈴木はる江, 堀田晴美
- Organizer
  第67回日本老年医学会関東甲信越地方会, 東京, 2018年3月3日
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 皮膚刺激による膀胱の排尿収縮の抑制性調節の加齢変化2018
- Author(s)
  堀田晴美，鈴木はる江, 飯村佳織, 渡辺信博
- Organizer
  第95回日本生理学会大会, 高松, 2018年3月28-30日
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 麻酔下ラットにおける咽頭への触刺激は甲状腺からのサイロキシン（T4）およびカルシトニン分泌を促進する2018
- Author(s)
  飯村佳織, 遠田明子, 鈴木はる江, 堀田晴美
- Organizer
  第13回環境生理学プレコングレス, 高松, 2018年3月27日
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] Age-related changes in neuromodulatory control of bladder micturition contractions originating in the skin2017
- Author(s)
  Hotta H
- Organizer
  The 70th Japan Society of Neurovegetative Research (JSNR) Congress in 2017，Nagoya, August 31-September 1, 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 麻酔下ラットの咽頭部への触刺激が甲状腺ホルモン(T4)分泌に与える影響2017
- Author(s)
  飯村佳織, 堀田晴美, 鈴木はる江, 遠田明子
- Organizer
  第45回自律神経生理研究会, 東京, 2017年12月2日
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] Stimulation of the superior laryngeal nerve promotes calcitonin and thyroxine secretion, without changes in parathormone secretion, from the thyroid and parathyroid glands.2017
- Author(s)
  Hotta H, Onda A, Suzuki H, Milliken P, Sridhar A
- Organizer
  The 10th Congress of the International Society for Autonomic Neuroscience (ISAN), Nagoya, August 30-September 2, 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] Age-related changes in inhibition of bladder contractions produced by activation of skin afferent Aβ, Aδ, and C- fibers2017
- Author(s)
  堀田晴美, 鈴木はる江, 飯村佳織, 渡辺信博
- Organizer
  第40回日本神経科学大会，幕張，2017年7月20-23日
- Data Source
  KAKENHI-PROJECT-17K01550
[Presentation] 散歩と脳血流の関係についての基礎研究2015
- Author(s)
  堀田晴美
- Organizer
  第38会日本基礎老化学会大会
- Place of Presentation
  横浜
- Year and Date
  2015-06-13
- Invited
- Data Source
  KAKENHI-PROJECT-24500635

1. UCHIDA Sae (90270660)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. SATO Akio (60072980)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KIMURA Atsuko (60214863)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SUZUKI Harue (00124412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 鈴木敦子 (80162923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 永井信夫 (90260281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 柏木仁美 (00260282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 長田理 (10260283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西宗裕史 (40870043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 重本和宏 (40284400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. AIZAWA Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 井川靖彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 本間之夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 井上富雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 徳永亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 渡辺憲史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 清水孝彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hotta Harumi 堀田 晴美

HOTTA Harumi 堀田 晴美

Research Projects

Research Products

Co-Researchers

嚥下にともなう自律神経の活性化が骨格筋におよぼす作用とサルコペニア予防への応用Principal Investigator

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Review Section

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Studies on mechanism of hormonal secretion from thyroid gland associated with swallowing for possible application to frail preventionPrincipal Investigator

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Neural mechanisms of the effects of masticatory activity on cerebral functionsPrincipal Investigator

Principal Investigator

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Effect of stimulation of the nucleus basalis of Meynert on BDNF in the cerebral cortex.Principal Investigator

Principal Investigator

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EFFECTS OF ACTIVATING THE CHOLINERGIC VASODILATIVE SYSTEM ORIGINATING IN THE BASAL FOREBRAIN ON BLOOD FLOW AND DELAYED NEURONAL DEATH FOLLOWING TRANSIENT ISCHEMIAPrincipal Investigator

Principal Investigator

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Research Institution

ニコチン性アセチルコリン受容体による虚血性神経細胞死と脳微小血管の制御Principal Investigator

Principal Investigator

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Research Institution

老化ラットにおける排尿機能の神経性調節Principal Investigator

Principal Investigator

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意識下動物における脳の微細血管の直視下連続的観察法の開発Principal Investigator

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老化ラットにおける脳局所血流とその自律神経性調節Principal Investigator

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老化ラットにおける眼底血流とその自律神経性調節Principal Investigator

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A development of a new method for continuous measurement of regional cerebral blood flow and analysis of the regulation of cerebral blood flow in a conscious rat.

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Elucidation of the autonomic nervous control of immune organs.

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[Book] 人体の構造と機能及び疾患．５章 加齢と疾患2024

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Hotta Harumi 堀田晴美

HOTTA Harumi 堀田晴美

[Book] 人体の構造と機能及び疾患．５章加齢と疾患2024