NAGAI Nobuo 永井信夫

… Alternative Names

永井信夫ナガイノブオ

NAGAI Nobuyuki 永井信行

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Researcher Number	90260281
Affiliation (Current)	2025: 長浜バイオ大学, バイオサイエンス学部, 教授
Affiliation (based on the past Project Information) *help	2010 – 2017: 長浜バイオ大学, バイオサイエンス学部, 教授 2014: 長浜バイオ大学, アニマルバイオサイエンス学科, 教授 2012: 長浜バイオ大学, アニマルバイオサイエンス学科, 教授 2010: 長浜バイオ大, バイオサイエンス学部, 教授 2008 – 2009: 近畿大学, 医学部, 講師 … More 1997 – 1999: 浜松医科大学, 医学部, 助手 1995: Hamamatsu Univ.Sch.of Med.Dept.of Physiology research associate, 医学部, 助手 1993: (財)東京都老人総合研究所, 自律神経部門, 助手 Less
Review Section/Research Field	Principal Investigator General physiology Except Principal Investigator Tumor therapeutics / General physiology / General pharmacology / General physiology / 神経・脳内生理学 / Clinical oncology
Keywords	Principal Investigator 脳梗塞 / 線溶因子 / 血液脳関門 / 血管透過性 / uPA / ｔPA / プラスミノゲン / マトリックスメタロプロテイナーゼ / MMP / 組織リモデリング … More / プラスミン / 線溶系 / 虚血 / マウス病態モデル / 酸素グルコース除 / 酸素グルコース除去 / bEnd.3 / 脳定量障害モデル / 血管内皮細胞 / ウロキナーゼ / ウロキナーゼレセプター / 血管新生 / uPAR / 病態生理 … More Except Principal Investigator 分子標的治療 / 組織型プラスミノーゲン活性化因子 / 線溶系 / プラスミノーゲン / 血液レオロジー / 血液凝固 / 抗がん剤耐性 / plasminogen / tumor metastasis & invasion / angiogenesis / angiostatin / 線溶 / 腫瘍増殖・転移 / 血管新生 / アンギオスタチン / cell growth / plasminogen activator inhibitor / plasminogen activator / urokinase receptor / urokinase / プラスミノーゲンアクチベータ- インヒビター / プラスミノーゲンアクチベータ- / プラスミノーゲン・アクチベータ-・インヒビター / プラスミノーゲン・アクチベータ- / 細胞増殖 / プラスミノーゲンアクチベータ-インヒビター / プラスミノーゲン・アクオベータ- / ウロキナーゼ受容体 / ウロキナーゼ / somatic stimulation / splenic blood flow / splenic sympathetic nerve / natural kiler cell / 体性感覚刺激 / 脾臓血流 / 脾臓交感神経 / NK活性 / マトリックスメタロプロテアーゼ / 血液脳関門透過性 / 組織型プラスミノゲン活性化因子 / ES細胞 / t-PAR / 血管平滑筋細胞 / 蛋白分解活性 / 血管 / 組織修復 / 血管内皮細胞 / t-PA / t-PA受容体 / 脳梗塞 / 脳内出血 / 脳虚血 / スタヒロキナーゼ / マウス / 血栓溶解 / プラスミノーゲンアクチベ / ペプチド Less

Roles of fibrinolytic system on vascular permeability after ischemic strokePrincipal Investigator
- Principal Investigator
  
  Nagai Nobuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Nagahama Institute of Bio-Science and Technology
Functional analysis of novel oncogene dynAP and the identification of its inhibitors
- Principal Investigator
  
  Mizukami Tamio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Nagahama Institute of Bio-Science and Technology
Development of drug-resistance-overcoming agents targeting histone demethylase JARID1A
- Principal Investigator
  
  Tamio Mizukami
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Nagahama Institute of Bio-Science and Technology
Oncogenic properties of human dynactin-associated protein (dynAP)
- Principal Investigator
  
  MIZUKAMI Tamio
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Nagahama Institute of Bio-Science and Technology
Quantitative analysis of the roles of fibrinolysis system component on the vascular permeability after ischemic stroke by using new animal modelPrincipal Investigator
- Principal Investigator
  
  NAGAI Nobuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Nagahama Institute of Bio-Science and Technology
Role of tissue-type plasminogen activator and matrix metalloproteinase in dementia
- Principal Investigator
  
  SUZUKI Yasuhiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hamamatsu University School of Medicine
Analysis of vascular remodeling by t-PA/t-PAR system
- Principal Investigator
  
  MATSUO Osamu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kinki University
Roles of urokinase plasminogen activator receptor expressed in endothelial cells on deterioration of ischemic strokePrincipal Investigator
- Principal Investigator
  
  NAGAI Nobuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Nagahama Institute of Bio-Science and Technology
  Kinki University
New synthetic peptide enhances plasminogen activation and thrombolysis
- Principal Investigator
  
  OKADA Kiyotaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kinki University
The resolution of cerebralvascular disorder by tissue-type plasminogen activor and stromelysin-1
- Principal Investigator
  
  SUZUKI Yasuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Hamamatsu University School of Medicine
Analyses of the inhibitory mechanism of agiogenesis by plasminogen fragment
- Principal Investigator
  
  TAKADA Akikazu
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  HAMAMATU UNIVERSITY SCHOOL OF MEDECINE
Analyzes of the role of urokinase receptor cell growth
- Principal Investigator
  
  URANO Tetsumei
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
Elucidation of the autonomic nervous control of immune organs.
- Principal Investigator
  
  SATO Akio
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  神経・脳内生理学
- Research Institution
  Tokyo Metropolitan Institute of Gerontology (TMIG)

All 2018 2017 2016 2015 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Increase in blood-brain barrier permeability does not directly induce neuronal death but may accelerate ischemic neuronal damage2018
- Author(s)
  Chiemi Ohmori, Yusuke Sakai, Yasuki Matano, Yasuhiro Suzuki, Kazuo Umemura and Nobuo Nagai
- Journal Title
  
  Exp. Anim.
  
  Volume: 67 Issue: 4 Pages: 479-486
- DOI
  10.1538/expanim.18-0038
- NAID
  40021698493
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08194, KAKENHI-PROJECT-17K01482
[Journal Article] A Review of the Mechanisms of Blood-Brain Barrier Permeability by Tissue-Type Plasminogen Activator Treatment for Cerebral Ischemia.2016
- Author(s)
  Suzuki Y, Nagai N, Umemura K.
- Journal Title
  
  Front Cell Neurosci.
  
  Volume: -
- DOI
  10.3389/fncel.2016.00002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08194
[Journal Article] Human Dynactin-Associated Protein Transforms NIH3T3 Cells to Generate Highly Vascularized Tumors with Weak Cell-Cell Interaction.2015
- Author(s)
  Kunoh T, Wang W, Kobayashi H, Matsuzaki D, Togo Y, Tokuyama M, Hosoi M, Koseki K, Wada S, Nagai N, Nakamura T, Nomura S, Hasegawa M, Sasaki R, Mizukami T.
- Journal Title
  
  PLoS One.
  
  Volume: 10(8) Issue: 8 Pages: e0135836-e0135836
- DOI
  10.1371/journal.pone.0135836
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112006, KAKENHI-PROJECT-15H04314, KAKENHI-PROJECT-26640063, KAKENHI-PROJECT-25291053
[Journal Article] Urokinase-type plasminogen activator and plasminogen mediate activation of macrophage phagocytosis during liver repair in vivo.2012
- Author(s)
  Kawao N, Nagai N, Tamura Y, Horiuchi Y, Okumoto K, Okada K, Suzuki Y, Umemura K, Yano M, Ueshima S, Kaji H, Matsuo O.
- Journal Title
  
  Thromb Haemost
  
  Volume: 107 Issue: 04 Pages: 749-59
- DOI
  10.1160/th11-08-0567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590219, KAKENHI-PROJECT-23590268, KAKENHI-PROJECT-23590291, KAKENHI-PROJECT-23790260, KAKENHI-PROJECT-23790289, KAKENHI-PROJECT-24790227
[Journal Article] Spatiotemporal differences in vascular permeability after ischaemic brain damage2011
- Author(s)
  Yano M, Kawao N, Tamura Y, Okada K, Ueshima S, Nagai N, Matsuo O.
- Journal Title
  
  Neuroreport
  
  Volume: 22 Issue: 9 Pages: 424-7
- DOI
  10.1097/wnr.0b013e3283462dd9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590244, KAKENHI-PROJECT-23590291, KAKENHI-PROJECT-23790260
[Journal Article] A synthetic peptide derived from staphylokinase enhances plasminogen activator by tissue-type plasminogen activator.2011
- Author(s)
  Okada K, Ueshima S, Matsuno H, Nagai N, Kawao N, Tanaka M, Matsuo O.
- Journal Title
  
  J Thromb Haemost
  
  Volume: 9 Issue: 5 Pages: 997-1006
- DOI
  10.1111/j.1538-7836.2011.04257.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590219, KAKENHI-PROJECT-23590268, KAKENHI-PROJECT-23590291, KAKENHI-PROJECT-23790260
[Journal Article] Localization of plasminogen in mouse hippocampus, cerebral cortex, and hypothalamus.2011
- Author(s)
  Taniguchi Y, Inoue N, Morita S, Nikaido Y, Nakashima T, Nagai N, Okada K, Matsuo O, Miyata S
- Journal Title
  
  Cell Tissue Res 343
  
  Pages: 303-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590222
[Journal Article] A synthetic peptide derived from staphylokinase enhances plasminogen activator by tissue-type plasminogen activator.2011
- Author(s)
  Okada K, Ueshima S, Matsuno H, Nagai N, Kawao N, Tanaka M, Matsuo O
- Journal Title
  
  J Thromb Haemost (Epub ahead of print.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590222
[Journal Article] Urokinase-type plasminogen activator contributes to heterogeneity of macrophages at the border of damaged site during liver repair in mice.2010
- Author(s)
  Kawao N, Nagai N, Tamura Y, Okada K, Yano M, Suzuki Y, Umemura K, Ueshima S, Matsuo O.
- Journal Title
  
  Thromb Haemost
  
  Volume: 105 Issue: 05 Pages: 892-900
- DOI
  10.1160/th10-08-0516
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590219, KAKENHI-PROJECT-23590268, KAKENHI-PROJECT-23790260
[Journal Article] Plasminogen is essential for granulation tissue formation during the recovery process after liver injury in mice.2010
- Author(s)
  Kawao N, Nagai N, Ishida C, Okada K, Okumoto K, Suzuki Y, Umemura K, Ueshima S, Matsuo O
- Journal Title
  
  J Thromb Haemost 8
  
  Pages: 1555-1566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590222
[Journal Article] Systemic transplantation of embryonic stem cells accelerates brain lesion decrease and angiogenesis2010
- Author(s)
  Nagai N, Kawao N, Okada K, Okumoto K, Teramura T, Ueshima S, Umemura K, Matsuo O.
- Journal Title
  
  Neuroreport
  
  Volume: 21 Issue: 8 Pages: 575-9
- DOI
  10.1097/wnr.0b013e32833a7d2c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590244
[Journal Article] Role of plasminogen in macrophage accumulation during liver repair.2010
- Author(s)
  Kawao N, Nagai N, Okada K, Okumoto K, Ueshima S, Matsuo O
- Journal Title
  
  Thromb Res 125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590222
[Journal Article] Systemic transplantation of embryonic stem cells accelerates brain lesion decrease and angiogenesis.2010
- Author(s)
  Nobuo Nagai
- Journal Title
  
  NeuroReport
  
  Volume: 21 Pages: 575-579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590244
[Journal Article] Initial brain lesion size affects the extent of subsequent pathophysiological responses2010
- Author(s)
  Nagai N, Kawao N, Okada K, Ishida C, Okumoto K, Ueshima S, Suzuki Y, Umemura K, Matsuo O.
- Journal Title
  
  Brain Res
  
  Volume: 1322 Pages: 109-117
- DOI
  10.1016/j.brainres.2010.01.077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590244
[Journal Article] Initial brain lesion size affects the extent of subsequent pathophysiological responses2010
- Author(s)
  Nobuo Nagai
- Journal Title
  
  Brain Research 1322
  
  Pages: 109-117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590244
[Journal Article] Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor- related protein2009
- Author(s)
  鈴木康裕、永井信夫、山川花朱美、川上純一、Roger Lijnen、梅村和夫
- Journal Title
  
  Blood 114
  
  Pages: 3252-3358
- NAID
  10026400471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790204
[Journal Article] Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein.2009
- Author(s)
  Yasuhiro Suzuki, Nobuo Nagai, Kasumi Yamakawa, Junichi Kawakami, H.Roger Lijnen, Kazuo Umemura
- Journal Title
  
  Blood 114巻
  
  Pages: 3352-3358
- NAID
  10026400471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790204
[Presentation] Reactive oxygen species generation and neural network rearrangement is associated with the increase in vascular permeability after ischemic stroke.2017
- Author(s)
  34.Yasuki Matano, Kumiko Takayama, Ryosuke Ohi, Nobuo Nagai
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] 脳梗塞の傷害部位周辺での血管透過性亢進の修復におけるプラスミンの寄与2017
- Author(s)
  足立悠太、湯川直人、鈴木康裕、梅村和夫、永井信夫.
- Organizer
  第39回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] Reactive oxygen species generation and neural network rearrangement is associated with the increase in vascular permeability after ischemic stroke.2017
- Author(s)
  Yasuki Matano, Kumiko Takayama, Ryosuke Ohi, Nobuo Nagai
- Organizer
  第94回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] Roles of alpha2-antiplasmin on pathogenesis of non-alcoholic steatohepatitis under high-fat diet feeding.2016
- Author(s)
  Nagai N, Ono M, Utsuno T, Hirata T
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop
- Place of Presentation
  日本平ホテル
- Year and Date
  2016-10-17
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] 組織型プラスミノゲン活性化因子(tPA)およびプラスミノゲンが脳梗塞の機能学的回復および組織学的修復に及ぼす影響の検討2016
- Author(s)
  酒井祐輔、大森智恵美、永井信夫
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] α2-アンチプラスミン遺伝子欠損マウスに対する高脂肪食付与の影響2016
- Author(s)
  小野　雅、永井　信夫
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] プラスミンの生理学的新規基質の探索2016
- Author(s)
  木村　七海　　長谷川　慎　　永井　信夫
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] 血管内皮細胞上のα２アンチラスミンの新規の基質の同定2016
- Author(s)
  永井信夫、木村七海、長谷川慎
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] Roles of t-PA/plasmin system on the functional recovery and histological repair after ischemic stroke in mice.2016
- Author(s)
  Yasuki Matano, Kumiko Takayama, Ryosuke Ohi, Nobuo Nagai
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop.
- Place of Presentation
  日本平ホテル
- Year and Date
  2016-10-17
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] Identification of novel substrates of plasmin on endothelial cell.2016
- Author(s)
  Nanami Kimura, Makoto Hasegawa, Nobuo Nagai.
- Organizer
  The 1st Joint Meeting of ISFP and PA Workshop.
- Place of Presentation
  日本平ホテル
- Year and Date
  2016-10-17
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] プラスミンの生理学的新規基質の探索2015
- Author(s)
  木村　七海　　長谷川　慎　　永井　信夫
- Organizer
  第108回近畿生理学談話会
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] 組織型プラスミノーゲン活性化因子 (tPA)の脳梗塞後の組織的回復への関与の検討2015
- Author(s)
  酒井祐輔、鈴木康裕、梅村和夫、永井信夫
- Organizer
  第37回日本血栓止血学会学術総会
- Place of Presentation
  甲府総合市民会館
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] 血管透過性亢進が脳梗塞に及ぼす影響の検討2015
- Author(s)
  酒井祐輔、大森智恵美、永井信夫
- Organizer
  第108回近畿生理学談話会
- Place of Presentation
  近畿大学東大阪キャンパス
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K08194
[Presentation] The mechanism of enhancement on plasminogen activation and thrombolysis by synthetic nonadecapeptide.2013
- Author(s)
  Okada K, Ueshima S, Matsuno H, Kawao N, Tamura Y, Yano M, Nagai N, Matsuo O
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀 (東京)
- Data Source
  KAKENHI-PROJECT-22590219
[Presentation] Role of alpha2-antiplasmin on repair responses after brain damage2013
- Author(s)
  山田雅香、永井信夫
- Organizer
  日本生理学会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24590288
[Presentation] 脳梗塞後の行動障害における内因性組織型プラスミノゲン活性化因子の役割2012
- Author(s)
  Yasuhiro Suzuki, Malgorzata Zajda, Nobuo Nagai, Kazuo Umemura
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23790289
[Presentation] Spatiotemporal differences in vascular permeability after ischaemic brain damage in mice2012
- Author(s)
  永井信夫
- Organizer
  第89回日本生理学会
- Place of Presentation
  松本
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] 虚血性脳傷害後に伴う血管透性亢進の時間的および空間的な差異に関する検討2012
- Author(s)
  永井信夫、矢野昌人、河尾直之、田村行識、岡田清孝、上嶋繁、鈴木康裕、梅村和夫、松尾理
- Organizer
  第89回日本生理学会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] 肝修復過程におけるu-PAによるマクロファージの機能制御2012
- Author(s)
  河尾直之、永井信夫,田村行識,堀内喜高,奥本勝美,岡田清孝,矢野昌人,鈴木康裕,梅村和夫,梶博史,松尾理
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590219
[Presentation] Roles of urokinase-type plasminogen activator and plasminogen in both accumulation of macrophages and induction of their phenotype heterogeneity during liver repair.2012
- Author(s)
  Kawao N, Nagai N, Tamura Y, Okumoto K, Okada K, Yano M, Suzuki Y, Umemura K, Kaji H, Matsuo O.
- Organizer
  The 89th Annual Meeting of the Physiology Society of Japan.
- Place of Presentation
  Matsumoto
- Data Source
  KAKENHI-PROJECT-22590219
[Presentation] t-PA mediated brain injury : MMP-dependent and. independent mechanisms2011
- Author(s)
  NAGAI N, Suzuki Y, Umemura K, Lijnen HR
- Organizer
  23^<rd> Congress of the International Society of Thrombosis and Haemostasis
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] Impaired accumulation of macrophages and absence of their phenotype heterogeneity during liver repair in urokinase-deficient mice.2011
- Author(s)
  Kawao N, Nagai N, Tamura Y, Okumoto K, Okada K, Yano M, Suzuki Y, Umemura K, Ueshima S, Matsuo O.
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis.
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22590219
[Presentation] 傷害サイズがその後の病態生理学的プロセスに及ぼす影響2011
- Author(s)
  永井信夫、河尾直之、岡田清孝、鈴木康裕、奥本勝美、梅村和夫、松尾理
- Organizer
  第88回日本生理学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] 胚性幹細胞の移植による血管の増加と脳傷害の縮小の促進2011
- Author(s)
  永井信夫、河尾直之、寺村岳士、奥本勝美、福田寛二、鈴木康裕、梅村和夫、松尾理
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] t-PA mediated brain injury : MMP-dependent and-independent mechanisms2011
- Author(s)
  Nagai Nobuo
- Organizer
  23rd Congress of the International Society of Thrombosis and Haemostasis
- Place of Presentation
  Kyoto
- Year and Date
  2011-07-26
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] 傷害サイズがその後の病態生理学的プロセスに及ぼす影響2011
- Author(s)
  永井信夫
- Organizer
  第88回日本生理学会
- Place of Presentation
  パシフィコ横浜・会議センター
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] Roles of urokinase receptor(uPAR) on ischemic stroke2010
- Author(s)
  Nagai N, Okada K, Kawao N, Ishida C, Ueshima S, Matsuo O
- Organizer
  20^<th> International Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  Amsterdam, The Netherland
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] Syntetic nonadecapeptide (SAK22-40) enhances plasminogen activation and thrombolysis.2010
- Author(s)
  Okada K, Ueshima S, Matsuno H, Kawao N, Nagai N, Matsuo O.
- Organizer
  20th International Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  Amsterdam/ Nederland
- Data Source
  KAKENHI-PROJECT-22590219
[Presentation] 肝細胞上での蛋白分解カスケード増幅系による肝再生調節機構の解析2010
- Author(s)
  岡田清孝、上嶋繁、河尾直之、永井信夫、松尾理
- Organizer
  第31回日本炎症・再生学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590219
[Presentation] 脳傷害の大きさが傷害後の病態生理的反応及ぼす影響2010
- Author(s)
  永井信夫
- Organizer
  第10回日本抗加齢学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] 脳傷害の大きさが傷害後の病態生理的反応及ぼす影響2010
- Author(s)
  永井信夫、河尾直之、岡田清孝、上嶋繁、鈴木康裕、梅村和夫、松尾理
- Organizer
  第10回日本抗加齢医学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] 虚血性脳傷害の大きさと傷害後の病態生理的反応の関連2010
- Author(s)
  永井信夫
- Organizer
  第20回日本病態生理学会総会
- Place of Presentation
  奈良県立医科大学
- Year and Date
  2010-01-24
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] 虚血性脳傷害サイズは傷害後の病態生理的反応の程度に影響を及ぼす2010
- Author(s)
  永井信夫
- Organizer
  第33回血栓止血学会
- Place of Presentation
  鹿児島県城山観光ホテル
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] Roles of urokinase receptor (uPAR) on ischemic stroke2010
- Author(s)
  永井信夫
- Organizer
  20^<th> International Congress on Fibrinolysis and Proteolysis
- Place of Presentation
  NH Grand Hotel Krasnapolsky (The Netherland)
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21590244
[Presentation] 血管内皮細胞表面のプラスミンの基質の検討
- Author(s)
  木村七海、長谷川慎、永井信夫
- Organizer
  第36回日本血栓止血学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24590288
[Presentation] プラスミノゲン活性因子は虚血培養内皮細胞において血管内皮細胞増殖因子を誘導した。
- Author(s)
  鈴木康裕、永井信夫、山川花朱美、外村和也、梅村和夫
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-23790289
[Presentation] マウス中大脳動脈閉塞後の血液脳関門の加圧凍結法による電子顕微鏡観察.
- Author(s)
  鈴木康裕、村中祥悟、外村和也、山川花朱美、永井信夫、梅村和夫
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-23790289
[Presentation] 血管内皮細胞でのＴｉｅ-1およびＴｉｅ-2の発現におけるtPAの作用
- Author(s)
  高島里美、岩前拓志、永井信夫
- Organizer
  第36回日本血栓止血学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24590288
[Presentation] 脳梗塞に伴う傷害部位周辺での血管透過性の亢進におけるプラスミンの関与
- Author(s)
  湯川直人、鈴木康裕、梅村和夫、永井信夫
- Organizer
  第36回日本血栓止血学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24590288
[Presentation] 脳梗塞後の神経機能制御におけるプラスミノーゲンの寄与の検討
- Author(s)
  大森智恵美、高島里美、鈴木康裕、梅村和夫、永井信夫
- Organizer
  第36回日本血栓止血学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24590288
[Presentation] 脳梗塞後の修復におけるｔＰＡの関与
- Author(s)
  永井信夫
- Organizer
  第92回日本生理学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-24590288
[Presentation] 脳梗塞における組織型プラスミノーゲン活性化因子（ｔＰＡ）による神経機能障害への回復への関与の検討
- Author(s)
  酒井祐輔、森田真弘、大森智恵美、鈴木康裕、梅村和夫、永井信夫
- Organizer
  第36回日本血栓止血学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-24590288

1. MIZUKAMI Tamio (80367896)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. OKADA Kiyotaka (20185432)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
3. MATSUO Osamu (40030879)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
4. KAWAO Naoyuki (70388510)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
5. HASEGAWA Makoto (10367899)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SASAKI Ryuzo (60077378)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. UESHIMA Shigeru (30193791)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. SUZUKI Yasuhiro (00324343)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
9. YAMAKAWA Kasumi (70563287)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
10. TAKAHASHI Rei (60144565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. NAKAMURA Toshinobu (80403202)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. URANO Tetsumei (50193967)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TAKADA Akikazu (80092980)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. IHARA Hayato (00223298)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. TSURUYAMA Tatsuaki (00303842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SATO Akio (60072980)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KIMURA Atsuko (60214863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HOTTA Harumi (70199511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TAKADA Yumiko (90092981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Wada Shuichi (20378607)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SUZUKI Takayoshi (90372838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. MIYATA Naoki (50114674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Yoshida Minoru (80191617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Itoh Akihiro (40391859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 柏木仁美 (00260282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. MATANO Yasuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
27. ADACHI Yuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. KIMURA Nanami

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
29. COLLEN Desire

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. LIJNEN Roger

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. 佐々木裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGAI Nobuo 永井 信夫

永井 信夫 ナガイ ノブオ

NAGAI Nobuyuki 永井 信行

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Roles of fibrinolytic system on vascular permeability after ischemic strokePrincipal Investigator

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Quantitative analysis of the roles of fibrinolysis system component on the vascular permeability after ischemic stroke by using new animal modelPrincipal Investigator

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Roles of urokinase plasminogen activator receptor expressed in endothelial cells on deterioration of ischemic strokePrincipal Investigator

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[Journal Article] Increase in blood-brain barrier permeability does not directly induce neuronal death but may accelerate ischemic neuronal damage2018

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NAGAI Nobuo 永井信夫

永井信夫ナガイノブオ

NAGAI Nobuyuki 永井信行