INOUE Yoshiharu 井上善晴

… Alternative Names

Inoue Yoshiharu 井上善晴

井上善晴イノウエヨシハル

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Researcher Number	70203263
Other IDs
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Affiliation (Current)	2022: 京都大学, 農学研究科, 教授
Affiliation (based on the past Project Information) *help	2018 – 2022: 京都大学, 農学研究科, 教授 2012 – 2015: 京都大学, (連合)農学研究科(研究院), 准教授 2007 – 2011: Kyoto University, Grd Sch. Of Agile, Associate Professor 2010: Kyoto University, 大学院・農学研究科, 准教授 2005 – 2006: 京都大学, 農学研究科, 助教授 … More 2001 – 2002: 京都大学, 農学研究科, 助教授 1995 – 2000: Kyoto, Univ., Research Institute for Food Science, Associate Professor, 食糧科学研究所, 助教授 1995: 京都大学, 食料科学研究所, 助教授 1991 – 1994: 京都大学, 食糧科学研究所, 助手 1989: 京都大学, 食糧科学研究所, 助手 Less
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / Applied molecular and cellular biology / Applied microbiology / Basic Section 38060:Applied molecular and cellular biology-related / Basic Section 38020:Applied microbiology-related / Medium-sized Section 38:Agricultural chemistry and related fields Except Principal Investigator 応用微生物学・応用生物化学 / 応用微生物学・発酵学 / 発酵・醸造 / 生物資源科学
Keywords	Principal Investigator 酵母 / Saccharomyces cerevisiae / メチルグリオキサール / ストレス / MAPキナーゼ / TORC2 / Pkc1 / シグナル伝達 / 酸化的ストレス / グルタチオン … More / グリオキサラーゼI / 浸透圧 / ホスファチジルイノシトール / 核分裂 / 核形態 / Yap1 / ミトコンドリア / カタラーゼ / チトクローム c ペルオキシダーゼ / 呼吸欠損変異 / 過酸化水素 / 過酸化脂質 / 活性酵素 / 環境 / 分子進化 / ストレス応答 / two-component system / 細胞周期 / カルシウム / Snf1キナーゼ / MAP-キナーゼ / 情報伝達 / 代謝 / 細胞分裂 / 極性成長 / ボスファチジルイノシトール / Akt / インスリンシグナル / Plc1 / 脂肪細胞 / インスリンシグナル伝達 / IRS-1 / ホスファチジルイノシトール3.5-ビスリン酸 / 液胞 / DNA損傷チェックポイント / チェックポイントキナーゼ / セキュリン / セパラーゼ / コヒーシン / ジスルフィド結合 / 転写因子 / チオレドキシン / glyoxalase I / disulfide bond / glutathione / oxdative stress / transcription factor / 代謝ストレス / チロシンホスファターゼ / PI3キナーゼ / メンブレントラフィック / メチルグリキオサール / Metabolic stress / Yeast / Signal transduction / Methylglyoxal / MAP kinase / Tyrosine phosphatase / エデルフォシン / エルゴステロール / ホスファチジルセリン / Cdc42 / 低分子量Gタンパク質 / リン脂質 / 細胞膜脂質ドメイン / CWI経路 … More Except Principal Investigator Hansenula mrakii / Saccharomyces cerevisiae / 活性酸素 / グルタチオンペルオキシダーゼ / 酵母 / グルタチオン / 過酸化脂質 / 活性酸素ストレス / glutathione / OSR / Glutathione / catalase / glutathione peroxidase / Yap1 / 炭素-燐酸結合 / 炭素-燐酸結合開裂酵素 / グルタチオンペルオキシダ-ゼ / 脂質過酸化物 / プリンヌクレオシドホスホリラーゼ / ウリジンホスホリラーゼ / プロモーター / 塩基配列 / ヌクレオシドアナログ / Klebsiella / C-P結合 / C-P結合解裂酵素 / C-P結合加水分解酵素 / C-Pリアーゼ / CーP結合 / CーP結合解裂酵素 / CーP結合加水分解酵素 / CーPリア-ゼ / C-P bond / C-P bond cleavage enzyme / C-P hydrolase / C-P lyase / リン脂質 / コレステロール / 固定化菌体 / 老化 / 細胞膜 / glutahione peroxidase / yeast / phospholipid / cholesterol / lipid hydroperoxide / reactiev oxygen stress / Hansenula mvakii / ジーンターゲッテイング / 酸化的ストレス / グルタチオンペルオキシダーゼ / グルコース-6ーリン酸脱水素酵素 / ストレス耐性 / セHansenula mrakii / PCR / 発現ベクター / Reactive oxygen / Yeast / Glutathione peroxidase / Gene targeting / Hanseiwla mrakii / 清酒 / 酢酸イソアミル / 吟醸酒 / 清酒酵母 / アルコールアセチルトランスフェラーゼ / エステラーゼ / sake / isoamyl acetate / ginjo-sake / sake yeast / Hansenula mra kii / OSR1 / DOG2 / GSH2 / GPX / Catalase / yAP-1 / glutathione reductase / glutathione synthetase / MAP kinase / グルタチオンペルオキダーゼ / チオレドキシン / チオレドキシンペルオキシダーゼ / 熱ショックストレス / Zap1 / Msn2 / Osr1 / thioredoxin / thioredoxin peroxidase / heat shock stress / 澱粉 / セルロースジアセテート / グラフト共重合 / リアクティブプロセシング / 生分解性 / ふすま / ポリウレタンフォーム / 生分解中間体 / 液化 / 4,4-ジフェニルメタンジイソシアネート / 微生物 / 閉鎖系酸素消費量 / バイオマス / アセチル化 / 二軸エクストルーダー / 発ガン性 / 内分泌攪乱作用 / Starch / cellulose deacetat / graft copolymerization / reactive processing / biodegradability / bran / polyurethane foam / biodegraded intermedeate Less

細胞膜と細胞外構造体の協調的相互作用によるTORC2シグナルの活性制御モデルPrincipal Investigator
- Principal Investigator
  
  井上善晴
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Kyoto University
核はなぜ球なのか？：細胞核形態のダイナミズムと生理機能の合目的性の探索Principal Investigator
- Principal Investigator
  
  井上善晴
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 38:Agricultural chemistry and related fields
- Research Institution
  Kyoto University
Elucidation of the activation mechanism of TORC2 by cell membrane lipid component and low molecular weight G proteinPrincipal Investigator
- Principal Investigator
  
  Inoue Yoshiharu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Kyoto University
Nuclear morphology checkpoint: analysis of the nuclear division arrest causedPrincipal Investigator
- Principal Investigator
  
  Yoshiharu Inoue
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied microbiology
- Research Institution
  Kyoto University
Metabolic signaling: molecular mechanism and its physiological significance of TORC2 activation by glycolytic metabolitePrincipal Investigator
- Principal Investigator
  
  INOUE Yoshiharu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
Molecular mechanism of the collapse of cell polarity and arrest of cell growth by metabolic stressPrincipal Investigator
- Principal Investigator
  
  INOUE Yoshiharu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
Metabolic signaling : role and mechanism of a metabolic intermediate in glycolysisPrincipal Investigator
- Principal Investigator
  
  INOUE Yoshiharu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
Molecular mechanism for activation of yeast transcription factor Yap1 by post-translational modificationPrincipal Investigator
- Principal Investigator
  
  INOUE Yoshiharu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  KYOTO UNIVERSITY
Development of biodegradable plastics from various kinds of biomass and elucidation for the safety of biodegraded intermediates from them
- Principal Investigator
  
  YOSHIOKA Mariko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物資源科学
- Research Institution
  KYOTO UNIVERSITY
酵母のHOG-MAPキナーゼカスケードによる細胞周期調節機構の解析Principal Investigator
- Principal Investigator
  
  井上善晴
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto University
Intracellular dynamism of transcription factors and signal cross-talk in the stress response in yeast
- Principal Investigator
  
  KIMURA Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  KYOTO UNIVERSITY
酵母のグリオキサラーゼI遺伝子の分子進化とストレス応答機構の解析Principal Investigator
- Principal Investigator
  
  井上善晴 (井上喜晴)
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto University
Snyder libraryによる酵母の環境ストレス応答性遺伝子の単離と機能解析Principal Investigator
- Principal Investigator
  
  井上善晴
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto University
Molecular evolution of the adaptive mechanisms against reactive oxygen stress in yeast
- Principal Investigator
  
  KIMURA Akira
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  KYOTO UNIVERSITY
酵母と老化と活性酸素によるミトコンドリアDNAの損傷に及ぼすグルタチオンの影響Principal Investigator
- Principal Investigator
  
  井上善晴
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Kyoto University
Construction of energy-independent producing system of sake flavor by Hansenula yeasts
- Principal Investigator
  
  KIMURA Akira
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  KYOTO UNIVERSITY
Analyzes of physiological properties in defensive mechanisms against oxidative stress in yeasts
- Principal Investigator
  
  KIMURA Akira
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  KYOTO UNIVERSITY
Detection of hydroperoxides of phospholipid and cholesterol by a novel glutathione peroxidase
- Principal Investigator
  
  KIMURA Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  KYOTO UNIVERSITY
新規なヌクレオシドホスホリラーゼを用いるヌクレオシドアナログの設計とその作用機構
- Principal Investigator
  
  木村光
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  Kyoto University
脂資過酸化物耐性酵母の活性酵素消去系の解析
- Principal Investigator
  
  KIMURA Akira
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  Kyoto University
Genetic and enzymatic analyses of C-P bond cleavage enzyme in bacteria
- Principal Investigator
  
  MURATA Kousaku
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・発酵学
- Research Institution
  KYOTO UNIVERSITY
細菌のC-P結合開裂酵素の活性発現および反応機構の解析とその応用
- Principal Investigator
  
  MURATA Kousaku
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  発酵・醸造
- Research Institution
  Kyoto University

[Journal Article] Role of RhoGAP Rgd1 in Pkc1 signaling-related actin repolarization under heat shock stress in Saccharomyces cerevisiae.2021
- Author(s)
  Nomura Wataru、Futamata Ryota、Inoue Yoshiharu
- Journal Title
  
  Biochim. Biophys. Acta (General Subjects)
  
  Volume: 1865 Pages: 129853-129853
- DOI
  10.1016/j.bbagen.2021.129853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05949, KAKENHI-PROJECT-18H02168
[Journal Article] Methylglyoxal inhibits nuclear division through alterations in vacuolar morphology and accumulation of Atg18 on the vacuolar membrane in Saccharomyces cerevisiae.2020
- Author(s)
  Nomura Wataru、Aoki Miho、Inoue Yoshiharu
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Pages: 13887-13887
- DOI
  10.1038/s41598-020-70802-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05949, KAKENHI-PROJECT-18H02168
[Journal Article] Contribution of phosphatidylserine to Rho1- and Pkc1-related repolarization of the actin cytoskeleton under stressed conditions in Saccharomyces cerevisiae.2019
- Author(s)
  Nomura, W. and Inoue, Y.
- Journal Title
  
  Small GTPase
  
  Volume: 10 Pages: 449-455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02168
[Journal Article] Contribution of phosphatidylserine to Rho1- and Pkc1-related repolarization of the actin cytoskeleton under stressed conditions in Saccharomyces cerevisiae2019
- Author(s)
  Nomura Wataru、Inoue Yoshiharu
- Journal Title
  
  Small GTPases
  
  Volume: - Pages: 449-455
- DOI
  10.1080/21541248.2017.1339766
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15414, KAKENHI-PROJECT-18H02168
[Journal Article] Methylglyoxal activates the target of rapamycin complex 2-protein kinase C signaling pathway in Saccharomyces cerevisiae.2015
- Author(s)
  Nomura, W., and Inoue, Y.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 35 Pages: 1269-1280
- DOI
  10.1128/mcb.01118-14
- NAID
  120005615637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00522, KAKENHI-PROJECT-25660055
[Journal Article] Methylglyoxal activates target of rapamycin complex 2―protein kinase C signaling pathway in Saccharomyces cerevisiae.2015
- Author(s)
  Nomura, W, and Inoue, Y.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 35 Pages: 1269-1280
- NAID
  120005615637
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25660055
[Journal Article] Temperature dependent N-glycosylation of plasma membrane heat shock protein Hsp30p2012
- Author(s)
  Kamo, K., Takabatake, A., Inoue, Y. and Izawa, S
- Journal Title
  
  Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun
  
  Volume: Vol.420, No.1 Pages: 119-123
- DOI
  10.1016/j.bbrc.2012.02.126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380202
[Journal Article] Reduction of glucose uptake through inhibition of hexose transporters and enhancement of their endocytosis by methylglyoxal in Saccharomyces cerevisiae2012
- Author(s)
  Yoshida, A., Wei, D., Nomura, W., Izawa, S. and Inoue, Y
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: Vol.287, No.1 Pages: 701-711
- DOI
  10.1074/jbc.m111.322222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380202
[Journal Article] Involvement of glutathione peroxidase 1 in growth and peroxisome formation in Saccharomyces cerevisiae in oleic acid medium2012
- Author(s)
  T. Ohdate, Y. Inoue
- Journal Title
  
  Biochim. Biophys. Acta (Molecular and Cell Biology of Lipids)
  
  Volume: 1821 Pages: 1295-1305
- DOI
  10.1016/j.bbalip.2012.05.004
- NAID
  120004874010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J10274, KAKENHI-PROJECT-23380202
[Journal Article] Acetate but not propionate induces oxidative stress in bakers' yeast Saccharomyces cerevisiae.2011
- Author(s)
  Semchyshyn, H.M., Abrat, O.B., Miedzobrodzki, J., Inoue, Y., Lushchak, V.I.
- Journal Title
  
  Redox Report
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380187
[Journal Article] Glyoxalase system in yeasts : Structure, function, and physiology.2011
- Author(s)
  Inoue, Y., Maeta, K., Nomura, W.
- Journal Title
  
  Seminars in Cell & Developmental Biology
  
  Volume: (印刷中)
- NAID
  120003184063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380187
[Journal Article] Glyoxalase system in yeasts : Structure, function, and physiology.2011
- Author(s)
  Inoue, Y., Maeta, K., Nomura, W.
- Journal Title
  
  Seminars in Cell&Developmental Biology . Cell Biology of Glyoxalase in Microbial System and Human Disease (eds.Thornalley, P.J.and Rabbani, N.) vol.22
  
  Pages: 278-284
- NAID
  120003184063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380187
[Journal Article] Methylglyoxal activates Gcn2 to phosphorylate eIF2α independently of the TOR pathway in2010
- Author(s)
  Nomura, W., Maeta, K., Kita, K., Izawa, S., Inoue, Y.
- Journal Title
  
  Saccharomyces cerevisiae. Appl.Microbiol. Biotechnol. 86(6)
  
  Pages: 1887-1894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380187
[Journal Article] Regulatory mechanism for expression of GPX1 in response to glucose starvation and Ca^<2+> in Saccharomyces cerevisiae : Involvement of Snf1 and Ras/cAMP pathway in Ca^<2+> signaling.2010
- Author(s)
  Ohdate, T., Izawa, S., Kita, K., Inoue, Y.
- Journal Title
  
  Genes Cells 15(1)
  
  Pages: 59-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380187
[Journal Article] Calcineurin/Crzl destabilizes Msn2 and Msn4 in the nucleus in response to Ca^<2+> in2010
- Author(s)
  Takatsume, Y., Ohdate, T., Maeta, K., Nomura, W., Izawa, S., Inoue, Y.
- Journal Title
  
  Saccharomyces cerevisiae. Biochemical J. 427(2)
  
  Pages: 275-287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380187
[Journal Article] Role of Gcn4 for adaptation to methylglyoxal in Saccharomyces cerevisiae : methylglyoxal attenuates protein synthesis through phosphorylation of eIF2α.2008
- Author(s)
  Nomura, W., Maeta, K., Kita, K., Izawa, S., Inoue, Y.
- Journal Title
  
  Biochem. Biophys. Res.Commun. 376(4)
  
  Pages: 738-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20380187
[Journal Article] Modulation of Spc1 stress-activated protein kinase activity by methylglyoxal through inhibition of protein phosphatase in the fission yeast Schizosaccharomyces pombe2007
- Author(s)
  Takatsume, Y., Izawa, S., Inoue, Y
- Journal Title
  
  Biochem. Biophys. Res. Commun 363
  
  Pages: 572-580
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Msn2p/Msn4p-activation is essential for the recovery from freezing stress in yeast.2007
- Author(s)
  Izawa, S., Ikeda, K., Ohdate, T., and Inoue, Y.
- Journal Title
  
  Biochem. Biopys. Res. Commun. 352
  
  Pages: 750-755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Modulation of Spc1 stress-activated protein kinase activity by methylglyoxal through inhibition of protein phosphatase in the fission yeast Schizosaccharomyces pombe.2007
- Author(s)
  Takatsume, Y., Izawa, S., and Inoue, Y.
- Journal Title
  
  Biochem. Biophys. Res. Common. 363
  
  Pages: 572-580
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Modulation of Spc1 by methylglyoxal through inhibition of protein phosphatase in the fission yeast S. pombe.2007
- Author(s)
  Takatsume, Y., Izawa, S., and Inoue, Y.
- Journal Title
  
  Biochem. Biophys, Res. Commun. 363
  
  Pages: 942-947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Green tea polyphenols function as prooxidants to activate oxidative stress-responsive transcription factors in yeasts.2007
- Author(s)
  Maeta, K., Nomura, W., Takatsume, Y., Iawa, S., and Inoue, Y.
- Journal Title
  
  Appl. Environ. Microbiol. 73
  
  Pages: 572-580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Methylglyoxal as a signal initiator for activation of the stress-activated protein kinase cascade in the fission yeast Schizosaccharomyces pombe2006
- Author(s)
  Takatsume, Y., Izawa, S., Inoue, Y
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 9086-9092
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Asrl, an alcohol-responsive factor of Saccharomyces cerevisiae, is dispensable for alcoholic fermentation.2006
- Author(s)
  Izawa, S., Ikeda, K., Kita, T., Inoue, Y.
- Journal Title
  
  Appl. Microbiol. Biotechnol. 72(3)
  
  Pages: 560-565
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Methylglyoxal as a signal initiator for activation of the stress-activated protein kinase cascade in the fission yeast Schizosaccharomyces pombe.2006
- Author(s)
  Takatsume, Y., Izawa, S., Inoue, Y.
- Journal Title
  
  J. Biol. Chem. 281(14)
  
  Pages: 9082-9092
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Methylglyoxal as a signal initiator for activation of the stress-activated protein kinase cascade in the fission yeast Schizosaccharomyces pombe.2006
- Author(s)
  Takatsume, Y., Izawa, S., and Inoue, Y.
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 9086-9092
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Methylglyoxal, a metabolite derived from glycolysis, functions as a signal initiator of the high osmolarity glycerol-mitogen-activated protein kinase cascade and calcineurin/Crz1-mediated pathway in Saccharomyces cerevisiae.2005
- Author(s)
  Maeta, K., Izawa, S., and Inoue, Y.
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 253-260
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Cytosolic proteins as principal copper buffer in an early response to copper by yeast cells.2005
- Author(s)
  Bi, W., Inai, Y., Shiraishi, N., Maeta, K., Takatsume, Y., Inoue, Y., Nishikimi, M.
- Journal Title
  
  J.Clin.Biochem.Nutr. 36(1)
  
  Pages: 19-27
- NAID
  130004466422
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe.2005
- Author(s)
  Zuin, A., Vivancos, A.P., Sanso, M., Takatsume, Y., Ayte, J., Inoue, Y., Hidalgo, E.
- Journal Title
  
  J.Biol.Chem. 280(44)
  
  Pages: 36708-36713
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Unique regulation of glyoxalase I activity during osmotic stress response in the fission yeast Schizosaccharomyces pombe2005
- Author(s)
  Takatsume, Y., Izawa, S., Inoue, Y.
- Journal Title
  
  Arch.Microbiol. 183(3)
  
  Pages: 224-227
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Gpx2, encoding a phospholipid hydroperoxide glutathione peroxidase homologue, codes for an atypical 2-Cys peroxiredoxin in Saccharomyces cerevisiae2005
- Author(s)
  Tanaka, T., Izawa, S., Inoue Y.
- Journal Title
  
  J.Biol.Chem. 280(51)
  
  Pages: 42078-42087
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] a metabolite derived from glycolysis, functions as a signal initiator of the high osmolarity glycerol-mitogen-activated protein kinase cascade and calcineudn/Crz1-mediated pathway in Saccharomyces cerevisiae2005
- Author(s)
  Maeta, K., Izawa, S., Inoue, Y., Methylglyoxal
- Journal Title
  
  J. Biol. Chem 280
  
  Pages: 253-260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380201
[Journal Article] Methylglyoxal as a signal initiator for activation of the stress-activated protein kinase cascade in the fission yeast Schizosaccharomyces pombe.
- Author(s)
  Takatsume, Y., Izawa, S., Inoue, Y.
- Journal Title
  
  J.Biol.Chem. (印刷中)
- Data Source
  KAKENHI-PROJECT-17380201
[Presentation] Saccharomyces cerevisiaeにおけるピルビン酸デカルボキシラーゼI欠損は2-デオキシグルコース感受性を高める2022
- Author(s)
  宇田竜成、向山佳歩、野村亘、井上善晴
- Organizer
  日本農芸化学会 2022年度大会
- Data Source
  KAKENHI-PROJECT-21K19079
[Presentation] Saccharomyces cerevisiaeにおけるピルビン酸デカルボキシラーゼI欠損は2-デオキシグルコース感受性を高める2022
- Author(s)
  宇田竜成、向山佳歩、野村　亘、井上善晴
- Organizer
  日本農芸化学会　2022年度大会
- Data Source
  KAKENHI-PROJECT-21H02103
[Presentation] 出芽酵母ピルビン酸デカルボキシラーゼIの機能と細胞内局在性の関連2021
- Author(s)
  宇田竜成、向山佳歩、野村　亘、井上善晴
- Organizer
  酵母遺伝学フォーラム　第54回研究報告会
- Data Source
  KAKENHI-PROJECT-21H02103
[Presentation] 出芽酵母ピルビン酸デカルボキシラーゼIの機能と細胞内局在性の関連2021
- Author(s)
  宇田竜成、向山佳歩、野村亘、井上善晴
- Organizer
  酵母遺伝学フォーラム第54回研究報告会
- Data Source
  KAKENHI-PROJECT-21K19079
[Presentation] CWI経路が関わるTORC2 シグナル制御機構の解析2020
- Author(s)
  野村　亘、後藤　剛、高原照直、前田達哉、河田照雄、井上善晴
- Organizer
  第53回酵母遺伝学フォーラム
- Data Source
  KAKENHI-PROJECT-18H02168
[Presentation] 出芽酵母cell wall integrity経路が関わるTOR複合体2シグナル制御機構2019
- Author(s)
  野村　亘、後藤　剛、高原照直、前田達哉、河田照雄、井上善晴
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02168
[Presentation] メチルグリオキサールの生成を介したジヒドロキシアセトンによる出芽酵母の細胞増殖阻害2019
- Author(s)
  野村　亘、青木美穂、後藤　剛、河田照雄、井上善晴
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-18H02168
[Presentation] Edelfosineを用いたTOR複合体2シグナル制御機構の解析2019
- Author(s)
  野村　亘、後藤　剛、高原照直、前田達哉、井上善晴
- Organizer
  第52回酵母遺伝学フォーラム
- Data Source
  KAKENHI-PROJECT-18H02168
[Presentation] Pkc1安定性とリン酸化状態との関連性2018
- Author(s)
  野村　亘、今井杏理紗、後藤　剛、河田照雄、井上善晴
- Organizer
  第51回酵母遺伝学フォーラム
- Data Source
  KAKENHI-PROJECT-18H02168
[Presentation] 出芽酵母PKCのリン酸化状態が安定化に及ぼす影響2018
- Author(s)
  野村　亘、今井杏理紗、後藤　剛、河田照雄、井上善晴
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02168
[Presentation] 出芽酵母のTORC2-Pkc1シグナルにおけるPog1の機能解析2018
- Author(s)
  名波谷政希、野村　亘、池田佳代、井上善晴
- Organizer
  第51回酵母遺伝学フォーラム
- Data Source
  KAKENHI-PROJECT-18H02168
[Presentation] メチルグリオキサール生成を介したジヒドロキシアセトンによる細胞増速と核分配阻害2018
- Author(s)
  池田佳代、野村　亘、青木美穂、井上善晴
- Organizer
  第51回酵母遺伝学フォーラム
- Data Source
  KAKENHI-PROJECT-18H02168
[Presentation] メチルグリオキサールによる酵母DNA損傷チェックポイントの活性化2016
- Author(s)
  塩尻敦史、野村　亘、井上善晴
- Organizer
  日本農芸化学会関西支部第493回講演会
- Place of Presentation
  楽友会館（京都市左京区）
- Year and Date
  2016-02-06
- Data Source
  KAKENHI-PROJECT-25660055
[Presentation] メチルグリオキサールによる新しいインスリン抵抗性モデル2014
- Author(s)
  井上善晴
- Organizer
  日本農芸化学会（2014年度大会）シンポジウム
- Place of Presentation
  明治大学
- Invited
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] メチルグリオキサールによる新しいインスリン抵抗性モデル2014
- Author(s)
  井上善晴
- Organizer
  日本農芸化学会, 2014年度大会シンポジウム(アルデヒドのバイオサイエンス -生物の多様なアルデヒド代謝系とその戦略的活用)
- Place of Presentation
  明治大学生田キャンパス(川崎市)
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] 解糖系代謝物によるTORC2シグナルの活性化2013
- Author(s)
  野村亘, 河田照雄, 井上善晴
- Organizer
  第36回日本分子生物学会ワークショップ(TOR ROAD-TORへの道, TORからの道)
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] Pkc1のC1領域がTORC2-Pkc1シグナルに及ぼす影響2013
- Author(s)
  野村　亘、河田照雄、井上善晴
- Organizer
  第46回酵母遺伝学フォーラム
- Place of Presentation
  東北学院大学
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] Pkc1のC1領域がTORC2-Pkc1シグナルに及ぼす影響2013
- Author(s)
  野村亘, 河田照雄, 井上善晴
- Organizer
  第46回酵母遺伝学フォーラム
- Place of Presentation
  東北学院大学(仙台市)
- Year and Date
  2013-09-08
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] 解糖系代謝物によるTORC2シグナルの活性化2013
- Author(s)
  野村　亘、河田照雄、井上善晴
- Organizer
  第36回日本分子生物学会ワークショップ： TOR ROAD-TORへの道、TORからの道
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] 酵母を利用した健康科学への挑戦2013
- Author(s)
  井上善晴
- Organizer
  平成24年度置賜マイクロ・ナノバイオフォーラム(微生物反応を利用した産業創出~生命・化学・産業~)
- Place of Presentation
  伝統の杜・置賜文化ホール(米沢市)
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] 解糖系代謝物メチルグリオキサールによるIRS-1のリン酸化を介したインスリン抵抗性の可能性2013
- Author(s)
  野村亘, 河田照雄, 井上善晴
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学(仙台市)
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] TORC2シグナリングの解析 : 糖尿病病態解析モデルとしての酵母2012
- Author(s)
  野村亘, 河田照雄, 井上善晴
- Organizer
  第45回酵母遺伝学フォーラム
- Place of Presentation
  京都大学きはだホール(宇治市)
- Year and Date
  2012-09-04
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] 解糖系代謝物によるTORC2活性化機構～酵母を用いる糖尿病研究の可能性～2012
- Author(s)
  野村亘、井上善晴
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学(シンポジウム)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] 解糖系代謝物メチルグリオキサールはTORC2の活性化因子である2012
- Author(s)
  野村亘, 河田照雄, 井上善晴
- Organizer
  第59回日本生化学会近畿支部例会
- Place of Presentation
  京都大学宇治キャンパス(宇治市)
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] 解糖系代謝物によるTORC2活性化機構~酵母を用いる糖尿病研究の可能性~2012
- Author(s)
  野村亘, 井上善晴
- Organizer
  日本農芸化学会2012年度大会シンポジウム(メタボリックシグナルと健康科学)
- Place of Presentation
  京都女子大学(京都市)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-23380202
[Presentation] ホスホリパーゼCとTORC2を介したPKC制御機構の解析2010
- Author(s)
  野村亘、井上善晴
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会・合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20380187
[Presentation] ホスホリパーゼCとTORC2を介したPKC制御機構の解析2010
- Author(s)
  野村亘、井上善晴
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会・合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20380187
[Presentation] Role of TORC2 in activation of MAPK in yeast2009
- Author(s)
  野村亘、喜多恵子、井沢真吾、井上善晴
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20380187
[Presentation] Plc1を介したPkc1-Mpk1シグナル伝達系の活性化機構2009
- Author(s)
  野村亘、喜多恵子、井沢真吾、井上善晴
- Organizer
  第42回酵母遺伝学フォーラム
- Place of Presentation
  つくば
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20380187
[Presentation] 解糖系代謝物メチルグリオキサールによるjellybeans型の核形態変化2009
- Author(s)
  橋本真希、野村亘、喜多恵子、井沢真吾、井上善晴
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-20380187
[Presentation] 出芽酵母におけるホスホリパーゼCを介したPkc1-Mpk1経路の新奇活性化機構2009
- Author(s)
  野村亘、前田和宏、喜多恵子、井沢真吾、井上善晴
- Organizer
  Involvement of phospholipsae C in methylglyoxal-induced activation of the Pkc1-Mpk1 MAPK pathway in the budding yeast(第61回日本細胞生物学会合同大会)
- Place of Presentation
  名古屋
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20380187
[Presentation] スピンドル極体の配向形成におけるPtdIns(3,5)P_2の役割2008
- Author(s)
  野村亘、喜多恵子、井沢真吾、井上善晴
- Organizer
  Role of PtdIns (3,5) P_2 in determination of the orientation of spindle pole body in yeast(BMB2008-第31回日本分子生物学会年会・第81回日本生化学会大会合同大会)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20380187
[Presentation] メチルグリオキサールによるKar9のSPBへの非対称分布の崩壊2008
- Author(s)
  野村亘、前田和宏、喜多恵子、井沢真吾、井上善晴
- Organizer
  第41回酵母遺伝学フォーラム
- Place of Presentation
  北海道
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-20380187
[Presentation] ル代謝ならびに液胞形態の影響2007
- Author(s)
  野村亘、前田和宏、喜多恵子、井沢真吾、井上善晴
- Organizer
  第40回日本発生生物学会/第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2007-05-30
- Data Source
  KAKENHI-PROJECT-17380201
[Presentation] Methylglyoxal affects the metabolism of phosphatidylinositol and the vacuolar morphology in Saccharomyces cerevisiae2007
- Author(s)
  Nomura, W., Maeta, K., Kita, K., Izawa, S., Inoue, Y
- Organizer
  Joint Meeting of the Japanese Society of Developmental Biologist & the Japan Society for Cell Biology
- Place of Presentation
  Fukuoka
- Year and Date
  2007-05-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380201
[Presentation] 出芽酵母におけるメチルグリオキサールのホスファチジルイノシトール代謝ならびに液胞形態の影響2007
- Author(s)
  野村亘、前田和宏、喜多恵子、井沢真吾、井上善晴
- Organizer
  第40回日本発生生物学会/第59回日本細胞生物学会合同大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2007-05-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380201
[Presentation] TORC2-Pkc1シグナル経路のDNA損傷応答への関与
- Author(s)
  野村　亘、河田照雄、井上善晴
- Organizer
  第47回酵母遺伝学フォーラム
- Place of Presentation
  東京大学
- Year and Date
  2014-09-01 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-25660055

1. KIMURA Akira (80026541)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
2. IZAWA Shingo (10273517)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MURATA Kousaku (90142299)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KAWADA Teruo (10177701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. MANO Jun'ichi (50243100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. YOSHIOKA Mariko (30220594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIRAISHI Nobuo (70026508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAWASHIRNA Nobuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 野村亘

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

INOUE Yoshiharu 井上 善晴

Inoue Yoshiharu 井上 善晴

井上 善晴 イノウエ ヨシハル

Research Projects

Research Products

Co-Researchers

細胞膜と細胞外構造体の協調的相互作用によるTORC2シグナルの活性制御モデルPrincipal Investigator

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Review Section

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核はなぜ球なのか？：細胞核形態のダイナミズムと生理機能の合目的性の探索Principal Investigator

Principal Investigator

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Review Section

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Elucidation of the activation mechanism of TORC2 by cell membrane lipid component and low molecular weight G proteinPrincipal Investigator

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Review Section

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Nuclear morphology checkpoint: analysis of the nuclear division arrest causedPrincipal Investigator

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Metabolic signaling: molecular mechanism and its physiological significance of TORC2 activation by glycolytic metabolitePrincipal Investigator

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Molecular mechanism of the collapse of cell polarity and arrest of cell growth by metabolic stressPrincipal Investigator

Principal Investigator

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Metabolic signaling : role and mechanism of a metabolic intermediate in glycolysisPrincipal Investigator

Principal Investigator

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Molecular mechanism for activation of yeast transcription factor Yap1 by post-translational modificationPrincipal Investigator

Principal Investigator

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Principal Investigator

Project Period (FY)

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酵母のHOG-MAPキナーゼカスケードによる細胞周期調節機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Principal Investigator

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酵母のグリオキサラーゼI遺伝子の分子進化とストレス応答機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Snyder libraryによる酵母の環境ストレス応答性遺伝子の単離と機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

INOUE Yoshiharu 井上善晴

Inoue Yoshiharu 井上善晴

井上善晴イノウエヨシハル