Muramatsu Tomonari 村松知成

… Alternative Names

村松知成ムラマツトモナリ

MURAMATSU Tomonari 村松知成

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Researcher Number	70212256
External Links
Affiliation (Current)	2025: 東京大学, 大学院農学生命科学研究科(農学部), 特任准教授
Affiliation (based on the past Project Information) *help	2018 – 2020: 東京大学, 大学院農学生命科学研究科(農学部), 特任准教授 2008 – 2010: The Institute of Physical and Chemical Research, システム研究チーム, 上級研究員 2004: RIKEN, Protein Structure Team, Senior Research Scientist, タンパク質構造研究チーム, 上級研究員 2001 – 2003: 国立がんセンター, 研究所・生物物理部, 室長 2000: 国立がんセンター, 生物物理部, 室長 … More 1998 – 2000: 国立がんセンター研究所, 生物物理部, 室長 1999: Nat. Cancer Cent. Res. Inst., Biophysics Div., Section Chief, 研究所・生物物理部, 室長 1997: 国立がんセンター, 生物物理部, 室長 1995: 国立がんセンター研究所, 生物物理部, 室長 1995: National Institute for Cancer Research, Department of Biophysical Chemistry, Lab, 生物物理部, 室長 1994: 東京大学, 大学院理学系研究科, 助手 1993 – 1994: 東京大学, 大学院・理学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Biological Sciences / Functional biochemistry / Basic Section 43030:Functional biochemistry-related / Structural biochemistry Except Principal Investigator Structural biochemistry / Biological pharmacy / Biophysics
Keywords	Principal Investigator ATP依存性プロテアーゼ / 結晶化 / 高度好熱菌 / ミトコンドリア / プロテアーゼ / 大腸菌 / eRF1 / 基質認識 / SARS / マウス … More / ピコルナウイルス / ウイルス / メインプロテアーゼ / 3CLプロテアーゼ / ポリタンパク質 / コロナウイルス / human / translation termination / codon recognition / stop codon / protein biosynthesis / eukaryote / ヒト / 翻訳終結 / コドン認識 / 終止コドン / タンパク質生合成系 / 真核生物 / X線結晶構造解析 / 特異性 / 立体構造 / 基質特異性 / プロセシング / 超遠心分析 / ATPアーゼ / ATP依存プロテアーゼ … More Except Principal Investigator NMR / 大腸菌 / Euplotes / X線結晶構造解析 / 超遠心分析 / ATP依存性プロテアーゼ / プロテアーゼ / Tetrahymena / ciliates / termination codon / genetic code / polypeptide release factor / システインtRNA / グルタミンtRNA / テトラヒメナ / tRNA合成酵素 / ポリペプチド鎖終結因子 / 翻訳終止コドン異常使用 / Tetramena / 繊毛虫 / 翻訳終止コドン / 遺伝暗号 / ペプチド鎖解離因子 / Subsite specificity / Chymotrypsin / Endopeptidase / Protease / Systematic specificity analysis / substrate specificity / Resin-bound peptide / Peptide libraty / 化学合成 / サブサイト特異性 / α-キモトリプシン / エンドペプチダーゼ / 系統的特異性検索法 / 基質特異性 / 樹脂固定化ペプチド / ペプチドライブラリー / Structural analysis / Three-dimensional structural analysis / x-ray crystallography / Nuclear magnetic resonance / Non-pepsin-type / Acid proteinase / 3次元構造 / 核磁気共鳴法 / 非ペプシン型酸性プロテアーゼ / クロコウジカビ / 構造解析 / 3次元構造解析 / 核磁気共鳴 / 非ペプシン型 / 酸性プロテアーゼ / X-ray crystallography / active site asparticacid residue / autocatalytic activation / site-directed mutagenesis / carboxyl proteinase / Proctase B / Proctase A / 部位指定突然変異導入法 / アスパラギン酸プロテアーゼ / 部位指定突然異導入法 / 前駆体活性化 / 活性中心カルボキシル基 / カルボキシルプロテアーゼ / 活性中心アスパラギン酸残基 / 自己触媒的活性化 / 部位特異的変異導入法 / カルボキシルプロテアーゼ / プロクターゼB / プロクターゼA / がん / アポトーシス / Myc / 光散乱 / 電子顕微鏡観察 / 多量体構造 / プロテアーゼLa / Lonプロテアーゼ / ATPアーゼ / ATP依存プロテアーゼ Less

Specificity of SARS-CoV 3CL proteasePrincipal Investigator
- Principal Investigator
  
  Muramatsu Tomonari
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokyo
Autoprocessing mechanism of SARS-CoV 3CL proteasePrincipal Investigator
- Principal Investigator
  
  MURAMATSU Tomonari
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  The Institute of Physical and Chemical Research
Molecular mechanism of stop codon recognition by eRF1Principal Investigator
- Principal Investigator
  
  MURAMATSU Tomonari
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  RIKEN
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ATP依存的タンパク質分解機構の解明:高度好熱菌Lonプロテアーゼの構造解析Principal Investigator
- Principal Investigator
  
  村松知成
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ATP依存的タンパク質分解機構の解明:高度好熱菌Lonプロテアーゼの構造解析Principal Investigator
- Principal Investigator
  
  村松知成
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
ミトコンドリアに存在するATP依存性プロテアーゼLonの構造と機能の解析Principal Investigator
- Principal Investigator
  
  村松知成
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
The role of translation releasing factor on codon recognition
- Principal Investigator
  
  KUCHINO Yoshiyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Cancer Center Research Institution
Myc依存型アポトーシスにおける制御分子の解明
- Principal Investigator
  
  野口耕司
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
大腸菌ATP依存性プロテアーゼLonの構造と機能
- Principal Investigator
  
  高橋健治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo University of Pharmacy and Life Science
大腸菌ATP依存性プロテアーゼLonの構造機能相関Principal Investigator
- Principal Investigator
  
  村松知成
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
大腸菌ATP依存性プロテアーゼLonの構造と機能
- Principal Investigator
  
  高橋健治
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Development of a systematic method for analyzing the specificity of proteases and its application
- Principal Investigator
  
  TAKAHASHI Kenji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
  The University of Tokyo
大腸菌ATP依存性プロテアーゼLonの構造と機能
- Principal Investigator
  
  TAKAHASHI Kenji
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
大腸菌ATP依存性プロテアーゼLonの基質特異性とタンパク質分解シグナルの検索Principal Investigator
- Principal Investigator
  
  村松知成
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Studies on Carboxyl Proteinases : Comparative Analysis of Functional Structures and Catalytic Mechanisms of Proctases A and B
- Principal Investigator
  
  TAKAHASHI Kenji
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Three-dimensional structural analysis of non-pepsin-type acid proteinase using NMR and x-ray crystaliography
- Principal Investigator
  
  TANOKURA Masaru
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo

All 2009 2008 2004 2003 2001 1997 1996

All Journal Article Book

[Book] レトロウイルスのがん遺伝子は細胞起源(菊池洋編)(ノーベル賞の生命科学入門 RNAが拓く新世界第4章)2009
- Author(s)
  村松知成
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-20570115
[Journal Article] The effect of Mutations in the Carboxyl-Terminal Region on the Catalytic Activity of Escherichia coli Signal Peptidase I2008
- Author(s)
  Kim, Y.-T., Yoshida, H., Kojima, M., Kurita, R., Nishii, W., Muramatsu, T., Ito, H., Park S.-J., Takahashi, K.
- Journal Title
  
  J.Biochem 143
  
  Pages: 237-242
- NAID
  10024908288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570115
[Journal Article] Analysis of dynamic structure of eukaryotic release factor 1(eRF1)2004
- Author(s)
  Tomonari Muramatsu, et al.
- Journal Title
  
  Bioimages 12
  
  Pages: 37-37
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570104
[Journal Article] Analysis of dynamic structure of eukaryotic release factor 1 (eRF1)2004
- Author(s)
  Tomonari Muramatsu, et al.
- Journal Title
  
  Bioimades 12
  
  Pages: 37-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570104
[Journal Article] Molecular mechanism of stop codon recognition by eukaryotic relase factor 1 (eRF1)2003
- Author(s)
  Tomonari Muramatsu, et al.
- Journal Title
  
  Biomages 11
  
  Pages: 44-44
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15570104
[Journal Article] Molecular mechanism of stop codon recognition by eukaryotic relase factor 1(eRF1)2003
- Author(s)
  Tomonari Muramatsu, et al.
- Journal Title
  
  Bioimages 11
  
  Pages: 44-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15570104
[Journal Article] The ciliate Euplotes octocarinatus expresses two polypeptide release factors of the type eRF1.2001
- Author(s)
  A.Liang, C.Brunen-Nieweler, T.Muramatsu, Y.Kuchino, H.Beier, K.Heckmann
- Journal Title
  
  Gene 262
  
  Pages: 161-168
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10044335
[Journal Article] Molecular mechanism of stop codon recognition by eRF1 : a wobble hypothesis for peptide anticodons.2001
- Author(s)
  T.Muramatsu, et al.
- Journal Title
  
  FEBS Letters 488
  
  Pages: 105-109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10044335
[Journal Article] Molecular mechanism of stop codon recognition by eRF1: a wobble hypothesis for peptide anticodons.2001
- Author(s)
  T.Muramatsu, K.Heckmann, C.Kitanaka, Y.Kuchino
- Journal Title
  
  FEBS Letters 488
  
  Pages: 105-109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10044335
[Journal Article] tRNAの使い分けによる翻訳制御1997
- Author(s)
  村松知成, 口野嘉幸
- Journal Title
  
  生化学 69
  
  Pages: 36-39
- NAID
  10007850057
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10044335
[Journal Article] Nonsense suppression in mammalian cells.1996
- Author(s)
  Y.Kuchino, T.Muramatsu
- Journal Title
  
  Biochimie 78
  
  Pages: 1007-1015
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10044335

1. TAKAHASHI Kenji (70011533)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. TANOKURA Masaru (60136786)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. INOUE Hideshi (20184765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KUCHINO Yoshiyuki (60124418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 野口耕司 (80291136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 北中千史 (70260320)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KLAUS Heckmann

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIKDBERG Beier

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HECKMANN Klaus

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. BEIER Hildberg

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. BEIER Hildbe

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. HECKMANN Kla

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Muramatsu Tomonari 村松 知成

村松 知成 ムラマツ トモナリ

MURAMATSU Tomonari 村松 知成

Research Projects

Research Products

Co-Researchers

Specificity of SARS-CoV 3CL proteasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Autoprocessing mechanism of SARS-CoV 3CL proteasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of stop codon recognition by eRF1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ATP依存的タンパク質分解機構の解明:高度好熱菌Lonプロテアーゼの構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ATP依存的タンパク質分解機構の解明:高度好熱菌Lonプロテアーゼの構造解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ミトコンドリアに存在するATP依存性プロテアーゼLonの構造と機能の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

大腸菌ATP依存性プロテアーゼLonの構造機能相関Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

大腸菌ATP依存性プロテアーゼLonの基質特異性とタンパク質分解シグナルの検索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Muramatsu Tomonari 村松知成

村松知成ムラマツトモナリ

MURAMATSU Tomonari 村松知成

[Book] レトロウイルスのがん遺伝子は細胞起源(菊池洋編)(ノーベル賞の生命科学入門 RNAが拓く新世界第4章)2009