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TAKAO Masashi  髙尾 雅

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高尾 雅  タカオ マサシ

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Researcher Number 70216612
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2017: 東北大学, 加齢医学研究所, 講師
2009 – 2010: 東北大学, 加齢医学研究所, 講師
2003 – 2007: Tohoku Univ., 1DAC, Dept.Mol.genetics, Lecturer, 加齢医学研究所, 講師
1998 – 2004: 東北大学, 加齢医学研究所, 助手
1998: 東北大学, 加齢研, 助手
1990: 北里大学, 衛生学部, 助手
Review Section/Research Field
Principal Investigator
Risk sciences of radiation/Chemicals / 環境影響評価(含放射線生物学)
Except Principal Investigator
環境影響評価(含放射線生物学) / Biological Sciences / Risk sciences of radiation/Chemicals / Obstetrics and gynecology / 物質生物化学
Keywords
Principal Investigator
DNA glycosylase / Base excision repair / Cancer / Aging / DNA repair / DNAグリコシラーゼ / 塩基除去修復 / 発がん / 老化 / DNA修復 … More / 活性酸素 / Reactive oxygene species / Knock-out mouse / Mitochondrion / Reactive oxygen species / ノックアウトマウス / ミトコンドリア … More
Except Principal Investigator
DNA修復 / 活性酸素 / 単鎖切断 / DNA repair / DNA損傷 / DNA damage / 老化 / XRCC1 / PARP / DNA切断 / 塩基損傷 / 塩基除去修復 / photo repair / circadian rhythm / ノックアウトマウス / 癌化 / 細胞老化 / APエンドヌクレアーゼ / プロテオミクス / 可視化解析 / DNA単鎖切断 / 除去修復 / 細胞死 / ポリADPリボシル化 / ミトコンドリア / 紫外線 / digital PCR / Digital PCR / 循環腫瘍DNA / 循環腫瘍細胞 / 抗癌剤耐性 / エクソソーム / 婦人科がん / Liquid Biopsy / Aging / cancer / DNA strand breaks / proteomics / visual analysis / reactive oxygen species / リアルタイム解析 / 放射線 / レーザー / 生体分子 / 癌 / 可視化 / 二重鎖切断 / 発癌 / glycosylase / oxidative DNA damage / base excision repair / チミングリコール / UVDE / 発がん / グリコシラーゼ / 活性酸素DNA修復 / excision repair / DNA break / 紫外線損傷 / repair deficient mouse / gene targeting / 青色光受容体 / ジーンターゲーティング / サーカディアンリズム / 光回復酵素 / 光回復 / 日周リズム / 修復欠損マウス / ジーンターゲッティング / Proliferation / Differentiation / Initiction of DNA relication / Embryogenesis / Protein phosphorylation / p98 DNA binding protein / Casein kinase II / D-kinase / 転写調節 / リン酸化ポリペプチドの生理活性 / 特異リン酸化ポリペプチド / 特異活性化因子 / 特異リン酸化タンパク質 / がん抑制遺伝子産物 / DNA合成開始調節 / 初期発生 / DNA結合性蛋白質 / 特異リン酸化蛋白質 / DNA結合性キナ-ゼ / 卵プロテインキナ-ゼ / ポリADPリボース / in situ解析 / PALF / ゲノム不安定性 / 乳がん / 癌治療 / トウスジュニックマウス / 遺伝子破壊 / 遺伝子組換え / ミトユンドリアDNA / 活性酵素 Less
  • Research Projects

    (12 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (16 People)
  •  Integrated analysis of circulating tumor cells and DNA toward clinical application of liquid biopsy.

    • Principal Investigator
      YAEGASHI Nobuo
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Novel DNA damage responses and repair regulated by poly-ADP ribosylation and chromatin remodeling

    • Principal Investigator
      YASUI Akira
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Tohoku University
  •  ゲノム単鎖切断に関わるゲノム不安定性と細胞死

    • Principal Investigator
      安井 明
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Live cell analysis of cellular responses to various types of DNA damage induced by reactive oxygen

    • Principal Investigator
      YASUI Akira
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Tohoku University
  •  Diversity and roles of novel enzymes for repair of oxidative DNA damagePrincipal Investigator

    • Principal Investigator
      TAKAO Masashi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Tohoku University
  •  Repair of oxidative DNA damage in Mammalian cells

    • Principal Investigator
      YASUI Akira
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Tohoku University
  •  Repair mechanism of oxidative DNA damage on the mitochondrial genomePrincipal Investigator

    • Principal Investigator
      MASASHI Takao
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Tohoku University
  •  塩基損傷・単鎖切断の修復ネットワークと細胞死

    • Principal Investigator
      YASUI Akira
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  ヒト細胞での遺伝子破壊系の開発とゲノム機能解析への応用

    • Principal Investigator
      安井 明
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Study of DNA repair deficient mice

    • Principal Investigator
      YASUI Akira
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Tohoku University
  •  Study of cellular responses to single-strand break

    • Principal Investigator
      YASUI Akira
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      Tohoku University
  •  The study on the biochemical mechanisms involved in the development of embyogensis

    • Principal Investigator
      OHTSUKI Kenzo
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Kitasato University School of Hygienic Science

All 2005 2003 2002

All Journal Article

  • [Journal Article] DNA repair initiated by glycosylases in the nucleus and mitochondria of mammalian cells ; how our cells respond to a flood of oxidative DNA damage2005

    • Author(s)
      Takao M., Yasui A.
    • Journal Title

      J Dermatol Sci. (in press)

    • NAID

      10020568049

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510039
  • [Journal Article] DNA repair initiated by glycosylases in the nucleus and mitochondria of mammalian cells ; how our cells respond to a flood of oxidative DNA damage2005

    • Author(s)
      Takao M., Yasui A.
    • Journal Title

      J Dermatol.Sci. (in press)

    • NAID

      10020568049

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15510039
  • [Journal Article] DNA repair initiated by glycosylases in the nucleus and mitochondria of mammalian cells ; how our cells respond to a flood of oxidative DNA damage2005

    • Author(s)
      Takao M, Yasui A.
    • Journal Title

      J Darmat Sci.Suppl. 1

    • NAID

      10020568049

    • Data Source
      KAKENHI-PROJECT-16201010
  • [Journal Article] DNA損傷・修復と老化2003

    • Author(s)
      安井明, 菅野新一郎, 高尾雅
    • Journal Title

      日本老年医学会雑誌 40・6

      Pages: 593-595

    • NAID

      10013681815

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15510039
  • [Journal Article] A Novel nuclear and mitochondrial glycosylases2002

    • Author(s)
      高尾 他
    • Journal Title

      EMRO J 21

      Pages: 3486-3493

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13480162
  • [Journal Article] Identification of 5-formyluracil DNA glycosylase activity of human hNTH1 protein.2002

    • Author(s)
      Miiyabe I., Zhang QM., Kino K., Sugiyama H., Takao M., Yasui A., Yonei S.
    • Journal Title

      Nucleic Acids Res. 30

      Pages: 3454-3463

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13480162
  • [Journal Article] A back-up glycosylase in Nth1-knockout mice2002

    • Author(s)
      高尾 他
    • Journal Title

      J.Biol.Cehm. 277

      Pages: 42205-42213

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13480162
  • [Journal Article] A Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III : homologue for repair of thymine glycol.2002

    • Author(s)
      Takao M, Kanno S, Shiromoto T, Hasegawa R, Ide H, Iikeda S, Sarker AH, Seki S, Xing JZ, Le XC, Weinfeld M, Kobayashi K, Miyazaki J, Muijtjens M, Hoeijmakers JHJ, van der Horst G, Yasui.
    • Journal Title

      EMBO J. 21

      Pages: 3486-3493

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13480162
  • [Journal Article] A back-up glycosylase in Nth1-knockout mice is a functional Nei (endonuclease VIII) homologue.2002

    • Author(s)
      Takao M, Kanno S, Kobayashi K, Zhang Q-M, Yonei S, van der Horst G, Yasui A.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 42205-42213

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13480162
  • 1.  YASUI Akira (60191110)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 4 results
  • 2.  NAKAJIMA Satoshi (00375114)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KANNO Shinichirou (10400417)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TANAKA Kouzo (00304452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  OHTSUKI Kenzo (60124559)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  OH-ISHI Masamichi (40233027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KUBOTA Yoshiko (30260102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YAEGASHI Nobuo (00241597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KITATANI Kazuyuki (40539235)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  岡村 均 (60158813)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  豊島 将文 (70451581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  ISHIBASHI Masumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MINATO Junko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  EKER A
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  VAN der Hors
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  BOOTSMA D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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