INUI Makoto 乾誠

Researcher Number	70223237
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Affiliation (based on the past Project Information) *help	2019 – 2021: 山口大学, その他部局等, 名誉教授 2017 – 2019: 山口大学, 大学院医学系研究科, 教授 2012 – 2016: 山口大学, 医学(系)研究科(研究院), 教授 2014 – 2015: 山口大学, 大学院医学系研究科, 教授 2010 – 2012: 山口大学, 大学院・医学系研究科, 教授 … More 2006 – 2007: 山口大学, 大学院・医学系研究科, 教授 1996 – 2007: Yamaguchi University, School of Medicine, Professor, 医学部, 教授 1994 – 1995: Osaka Univ.Med.Sch.Associate.Prof., 医学部, 助教授 1990 – 1993: Osaka University, School of Medicine, Assistant Professor, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator General pharmacology / General pharmacology / Neurochemistry/Neuropharmacology / 分子細胞生物学 / 応用薬理学・医療系薬学 Except Principal Investigator General medical chemistry / 医学一般 / Circulatory organs internal medicine / General pharmacology / Basic Section 48030:Pharmacology-related … More / Neurochemistry/Neuropharmacology / Neurophysiology and muscle physiology / Anesthesiology/Resuscitation studies / Cell biology / 血管生物学 / Legal medicine Less
Keywords	Principal Investigator ホスホランバン / 心筋小胞体 / 心不全治療薬 / SERCA / Calspectin / シナプシンI / カルスペクチン / アプタマー / 融合蛋白質 / 蛋白質間相互作用 … More / 強心薬 / Protein-protein interaction / PSD-95 / リン脂質 / Phospholipid / 燐脂質 / アネキシンVI / 細胞膜骨格 / ペプチド / カルシウム輸送 / 創薬 / 創傷治癒 / 角膜 / 心不全 / スクリーニング / カルシウム・ポンプ / カルシウム・イオン / Ca^<2+>ポンプ / NMDA受容体 / チロシン燐酸化 / 超微細構造解析 / ナノディスク / 皮膚創傷治癒 / 免疫抑制作用 / 蛍光標識架橋薬 / 血管誘導作用 / 創傷治癒促進作用 / 天然環状ペプチド / Screening / Intracellular Ca^<2+> transport / Cardiac sarcoplasmi reticulum / Phospholamban / A drug for heart failure / 蛋白質相互作用 / 蛋白質結 / 蛋白質精製法 / 細胞内Ca^<2+>輸送 / Zinc inhibition / Protein phosphorylation / NMDA receptor / Dimer formation / Chloride channels / Ion channels / 容積依存性Cl^-チャネル / 2量体 / 酵母two hybrid法 / ClC4 / Cl^-チャネル / NMDA受容体チャネル / チャネル / Zn^<2+>感受性 / 蛋白質燐酸化 / 2量体形成 / C1^-チャネル / イオン・チャネル / Phosphorylation / Calcium ion / Synapsin I / Annexin / リン酸化 / アネキシン / Phospholipids / SynapsinI / Annexins / Calcium regulation / Membrane skeleton / カルシウム / カルシウム制御 / Actin / Annexin VI / Calcium Ion / Membrane Skeleton / シナプス小胞 / Ca^<2+>チャンネル / アクチン / カルシウムイオン / アンギオテンシンI変換酵素 / 皮膚 / アンギオテンシン / インスリン様成長因子 / 細胞遊走 / 結晶構造解析 / 3次元結晶 / 2次元結晶 / 蛋白質精製 / 蛋白質結晶 / カルシウム輸送調節 / 上皮進展促進作用 / 組織培養 / Substance P / Insulin-like growth factor / 上皮 / 上皮伸展促進作用 / 細胞内Ca^<2+> / 燐酸化酵素 / IP_3 / サブスタンスP / IGF-1 / 角膜上皮細胞 / 上皮創傷治癒 / 組み換え蛋白質 / 組換え融合蛋白質 / チャンネル活性 / PSD / シナプス / リン酸化チロシン / テンシン / シナプス後肥厚部 … More Except Principal Investigator カルデスモン / Src / PKC / PSD-95 / アクチン / phospholamban / ホスホランバン / カルスペクチン / GKAP / Xenopus oocyte / MALS-2 / 転写制御 / 平滑筋細胞 / Caldesmon / 細胞骨格 / アネキシンVI / トロポミオシン / NMDA受容体 / heart failure / 心不全 / 形質転換 / 心筋小胞体 / Actin / 心筋細胞 / プロモーター / スプライシング / 細胞接着 / ペプチド / 細胞内導入 / oocyte / PDZ / phospholipids / oligomer / SERCA / sarcoplasmic reticulum / NMDA receptor / PDZ domain / calcium ATPase / カルシウムATPase / Xenopus oocytes / 二電極膜電位固定法 / アフリカツメガエル卵母細胞 / alpha-smooth muscle actin / alpha1 integrin / alpha-tropomyosin / caldesmon / phenotypic modulation / smooth muscle cell / 細胞外マトリクス / 平滑筋型α-アクチン / α1インテグリン / α-トロポミオシン / IGFI / Transcriptional regulation / Promoter / Smooth muscle cells / アクチン-ミオシン相互作用 / Exocytosis / Calpactin I / エクソサイト-シス / カルパクチンI / シナプシンI / 細胞膜骨格 / ゲルゾリン / カルシウムイオン / 神経成長円錐 / src遺伝子産物 / 動的接着部 / ミオシン / 質量分析 / 創傷治癒促進薬 / アンギオテンシン変換酵素 / アンギオテンシンII / 神経栄養因子 / 成長因子 / 表皮細胞 / 創傷治癒 / 環状ペプチド / ペプチド医薬 / 薬物送達 / 核酸アプタマー / Synapsis 1 / Chromaffin granules / Synaptic vesicles / Ca^<2+>制御 / カルモデュリン / Ca^<2+>結合蛋白質 / エクソサイトーシス / 神経シナプス / 副腎髄質 / クロマフィン顆粒 / シナプス小胞 / MAGUKs / SAP102 / SERCA2a / カルシウムATPaSe / G protein-coupled receptor(GPCR) / LPA receptor / vascular smooth muscle cell / atherosclerosis / dopamine receptor / postsvnantic density(PSD) / synapse / structure biology / 膜ターゲッティング / X線構造解析 / G蛋白質共役型受容体 / X線構造解 / 可塑性 / フーリエ変換 / 神経前駆細胞 / PSD-Zip45 / 膜蛋白質クラスター / ミリスチン酸化 / G蛋白質共役型受容体(GPCR) / 膜ターゲティング / LPAレセプター / 膜クラスター / PSD蛋白質 / ドーパミンD1レセプター / GPCR / 膜貫通型受容体 / G蛋白質共役受容体(GPCR) / LPA受容体 / 血管平滑筋細胞 / 動脈硬化症 / ドーパミン受容体 / シナプス後肥厚部(PSD) / シナプス / 構造生物学 / 燐酸化 / src / sarco (endo) plasmic reticulum / vascular smooth muscle / cardiac myocytes / 小胞体 / 血管平滑筋 / 心筋 / insulin / PDZ proteins / NMPA recptor / 亜鉛 / プロテインキナーゼC / チロシンリン酸化酵素 / グルタミン酸受容体 / PDZ protein / インスリン / PDZ蛋白質 / transgenic mice / cardiac sarcoplasmic reticulum / トランスジェニックマウス / トランスへニックマウス / Two electrode voltage clamp / synthetic RNA / Muscle relaxants / Succinylcholine / Acetylcholine / Neuromuscular junction / Nicotinic acetylcholine receptor / アフリカツメガエル / 合成RNA / 筋弛緩薬 / サクシニルコリン / アセチルコリン / 神経筋接合部 / ニコチン性アセチルコリン受容体 / growth factors / extracellular matrix / トロホミオシン / 細胞内シグナル伝達系 / 細胞外マトリックス / 増殖因子 / laminin / 遺伝子発現制御 / ラミニン / Transcription factor / CArG box / Differentiation / 転写調節因子 / CArGボックス / Splicing / Genomic structure / Actomyosin system / Phenotypic modulation / エンハンサー / アクトミオシン系制御 / 平滑筋細胞分化 / 接着因子 / 遺伝子構造 / 平滑筋細胞形質転換 / Calspectin / Cytoskeleton / Annexin VI / Myosin / 細胞内局在 / 間接螢光抗体法 / Alternative splicing / Chromosome / Phenotyptic modulation / Smooth muscle / Tropomyosin / Calumodulin / ゲノムDNA / 平滑筋細胞の分化・脱分化 / cDNA / lーカルデスモン / hーカルデスモン / オルタナティブスプライシング / 染色体 / 形態変化 / 平滑筋 / カルモジュリン / Monoclonal Antibody / Ca^<2+> Pump ATPase / Synthetic Peptide / Intracellular Ca Transient / cardiac SR / Intracelluar Ca^<2+> Content Measuring System / Isolated Cardiomycyte / 単クロ-ン抗体 / CaポンプATPase / 合成ペプチド / 細胞内Ca動態 / 蛍光顕微鏡測光システム / 単離心筋細胞 / Membrane protein / Solubilization / Calcium ion / Active transport / Protein-protein interaction / Low angle laser light scattering / Muscle contraction / Ca^<2+> pump ATPase / 膜蛋白質 / 可溶化 / 能動輸送 / 蛋白質間相互作用 / レ-ザ-光散乱 / 筋収縮 / Ca輸送ATPase / Synapsin 1 / Ultrastructural Analysis / Biochemical Analysis / Cytoskeletal Protein / 免疫電顕法 / 急速凍結ディ-プエッチ法 / 細胞骨格架橋蛋白質 / αーアクチニン / 超微細形態学的解析 / 生化学的解析 / 細胞骨格蛋白質 / Oxygen-Free Radicals / Adhesion / Cell Injury / Myocardial Cell / Endothelial Cell / Neutrophil / 粘着 / リボキシゲナ-ゼ代謝 / 活性酸素ラジカル / 好中球粘着 / 細胞障害 / 血管内皮 / 好中球 / 心筋梗塞 / 心臓突然死 / セロトニン / MDMA / オートファジー / カルパイン / ミトコンドリア / ＭＤＭＡ / 急性心筋梗塞 / STAT5b / 前駆脂肪細胞 / 3T3L1 / STAT5 / PDZRN3 / 脂肪細胞分化 / プロモーター解析 / 収縮蛋白質 / 辺縁接着部 / シナプス小胞蛋白質 / カルシウム制御 / 細胞運動性 / 細胞運動 / ラウス肉腫ウイルス / アクチンフィラメント / PC12 / p60^<c-src> / アネキシンII / 形質変換 / 動的接着構造 Less

Mechanism of promoting wound healing by the coordinated action of growth factors and neurotrophic factors
- Principal Investigator
  
  Sakai Hiroki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Yamaguchi University
Development of Novel Cyclic Peptide Drugs Targeting Phospholamban for the Treatment of Heart Failure
- Principal Investigator
  
  Honda Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Yamaguchi University
Ultrastructural analysis of calcium transport system of cardiac sarcoplasmic reticulum for drug developmentPrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Elucidation of the molecular mechanisms by a cyclic peptide, SEK-1005 promotes skin wound healingPrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Development of cardiomyocyte-specific intracellular drug-delivery system for therapy of cardiac diseases
- Principal Investigator
  
  HONDA Takeshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Development of a new drug for heart failure targeting phospholambanPrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Mitochondrial dysfunction on acute myocardial infarction or MDMA poisoning
- Principal Investigator
  
  Shintnai-Ishida Kaori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  Kyoto Prefectural University of Medicine
  The University of Tokyo
Analysis of IGF-1 receptor-independent signaling from IGF-1 and its application for drug developmentPrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Study on the functions of PDZRN3, a novel regulator of adipogenesis, for the development of therapy for diabetes
- Principal Investigator
  
  HONDA Takeshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Development of a novel inotropic and lucitorpic agent for treatment of heart failurePrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
蛋白質結晶構造解析に基づく新たな心不全治療薬デザインのための基礎研究Principal Investigator
- Principal Investigator
  
  乾誠
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Analyses of the novel signal transduction mechanisms involved in the homeostasis of the intracellular calcium in the cardiovascular system.
- Principal Investigator
  
  KIMURA Yoshihiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Yamaguchi University
Analysis of the NMDA receptor-PDZ containing complexes as the drug targets
- Principal Investigator
  
  YAMADA Yasue
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
上皮創傷治癒におけるIGF-1の新たな機能の解明と創薬への応用Principal Investigator
- Principal Investigator
  
  乾誠
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Establishment of a novel analysis system for three-dimentional structure of transmembrane receptors based on neuronal and vascular cell plasticity
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Osaka University
Development of a new drug for heart failurePrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Molecular mechanisms of regulation of NMDA receptor by protein-protein interactions
- Principal Investigator
  
  YAMADA Yasue
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yamaguchi University
Molecular mechanisms of ion channel regulation by a protein-protein interactionPrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Yamaguchi University
Molecular mechanisums of regulation of NMDA receptor by post-synaptic density proteins
- Principal Investigator
  
  YAMADA Yasue
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yamaguchi University
A novel mechanism of serco (endo) plasmic reticulum calcium regulation in the cardiovascular system
- Principal Investigator
  
  KIMURA Yoshihiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  Yamaguchi University
新たな作用点を持った強心薬スクリーニング法の開発Principal Investigator
- Principal Investigator
  
  乾誠
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Yamaguchi University
Study on chronic heart failure using mutant phospholamban transgenic mice
- Principal Investigator
  
  KIMURA Yoshihiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yamaguchi University
The effects of muscle relaxants on adult-type and fetal-type nictinic acetylcholine receptors
- Principal Investigator
  
  YAMADA Yasue
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
シナプス後肥厚部蛋白質の機能解析による神経シナプス形成の研究Principal Investigator
- Principal Investigator
  
  乾誠
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamaguchi University
細胞骨格機能制御解析による神経可塑性の研究Principal Investigator
- Principal Investigator
  
  乾誠
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Molecular and cell biolobical analysis of the smooth muscle cell differentiation
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Developing a culture system of differentiated smooth muscle cells and phathological application
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University
Regulation of cytoskeleton by annexin VIPrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yamaguchi University
  Osaka University
細胞骨格系による中枢シナプス機能発現の分子機作に関する研究
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
悪性細胞に特有の細胞基質間接着構造の分子構築と機能解析
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Transcriptional regulation of caldesmon gene in smooth muscle cells
- Principal Investigator
  
  HAYASHI Kenichiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  血管生物学
- Research Institution
  Osaka University
がん細胞に特有な細胞接着構造の分子構築の解明
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
細胞骨格系による中枢シナプス機能発現の分子機作に関する研究
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Molecular Mechanism of the differentiation of smooth muscle cells
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Interaction of annexins with membrane skeletal proteins in brainPrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Osaka University
細胞骨格系による中枢シナプス機能発現に分子機作に関する研究
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Analyzes of dynamic molecular organization of the membrane skeleton
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  医学一般
- Research Institution
  Osaka University
癌細胞動的接着部の分子構築の解析
- Principal Investigator
  
  祖父江憲治
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Analysis for the Expressional Change of Caldesmon Isoforms during Phenotyptic Modulation of Smooth Muscle Cells
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University
Interaction between ion channels and membrane skeletonPrincipal Investigator
- Principal Investigator
  
  INUI Makoto
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  分子細胞生物学
- Research Institution
  Osaka University
がん細胞接着部における細胞接着因子と細胞膜裏打ち構造の役割
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Molecularphysiological analysis of calcium-signaling proteins in cardiac sarcoplasmic reticulum
- Principal Investigator
  
  TADA Michihiko
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Free Radical Generation and Cell Injury in Endothelial Cell Co-Incubated with Neutrophil
- Principal Investigator
  
  KUZUYA Tsunehiko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
A New Method for the Analyses of Cytoskeletal and Their Related Proteins
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  医学一般
- Research Institution
  Osaka University
Protein-protein interaction of detergent solubilized Ca^<2+>-ATPase during ATP hydrolysis analyzed by low-angle laser light scattering photometry coupled with high-performance gel chromatography.
- Principal Investigator
  
  TADA Michihiko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  医学一般
- Research Institution
  Osaka University School of Medicine
Role of Cytoskeletal System and its Regulation by Ca^<2+> in Exocytosis
- Principal Investigator
  
  SOBUE Kenji
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University

[Journal Article] Calcium/calmodulin-dependent regulation of Rac GTPases and Akt in histamine-induced chemotaxis of mast cells2021
- Author(s)
  Honda Takeshi、Nishio Yusuke、Sakai Hiroki、Asagiri Masataka、Yoshimura Kiyoshi、Inui Makoto、Kuramasu Atsuo
- Journal Title
  
  Cellular Signalling
  
  Volume: 83 Pages: 109973-109973
- DOI
  10.1016/j.cellsig.2021.109973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07319, KAKENHI-PROJECT-20H03749, KAKENHI-PROJECT-18K06892, KAKENHI-PROJECT-19K07320
[Journal Article] PDZRN3 protects against apoptosis in myoblasts by maintaining cyclin A2 expression2020
- Author(s)
  Honda T, Inui M
- Journal Title
  
  Scientific reports
  
  Volume: 10 Issue: 1 Pages: 1140-1140
- DOI
  10.1038/s41598-020-58116-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06892, KAKENHI-PROJECT-19K07320, KAKENHI-PROJECT-17H04033
[Journal Article] PDZRN3 regulates differentiation of myoblasts into myotubes through transcriptional and posttranslational control of Id22019
- Author(s)
  Takeshi Honda, Makoto Inui
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 234 Issue: 3 Pages: 2963-2963
- DOI
  10.1002/jcp.27113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06892, KAKENHI-PROJECT-16K15203, KAKENHI-PROJECT-17H04033
[Journal Article] Long-term Functioning of Allogeneic Islets in Subcutaneous Tissue Pretreated with a Novel Cyclic Peptide without Immunosuppressive Medication2018
- Author(s)
  Kuwabara Rei、Hamaguchi Masahide、Fukuda Takuya、Sakai Hiroki、Inui Makoto、Sakaguchi Shimon、Iwata Hiroo
- Journal Title
  
  Transplantation
  
  Volume: 102 Issue: 3 Pages: 417-425
- DOI
  10.1097/tp.0000000000001923
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15203, KAKENHI-PROJECT-17H01579, KAKENHI-PROJECT-17H04033, KAKENHI-PROJECT-16J06573, KAKENHI-PROJECT-16H06295
[Journal Article] Co-treatment with a C1B5 peptide of protein kinase Cγ and a low dose of gemcitabine strongly attenuated pancreatic cancer growth in mice through T cell activation2018
- Author(s)
  Ishiguro Susumu、Kawabata Atsushi、Zulbaran-Rojas Alejandro、Monson Kelsey、Uppalapati Deepthi、Ohta Naomi、Inui Makoto、Pappas Charalampos G.、Tzakos Andreas G.、Tamura Masaaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 495 Issue: 1 Pages: 962-968
- DOI
  10.1016/j.bbrc.2017.11.102
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15203, KAKENHI-PROJECT-17H04033
[Journal Article] Distinct Roles of Small GTPases Rac1 and Rac2 in Histamine H4Receptor?Mediated Chemotaxis of Mast Cells2018
- Author(s)
  Kuramasu Atsuo、Wakabayashi Mie、Inui Makoto、Yanai Kazuhiko
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 367 Issue: 1 Pages: 9-19
- DOI
  10.1124/jpet.118.249706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04033, KAKENHI-PROJECT-16K15203, KAKENHI-PLANNED-26117003
[Journal Article] A pyridone derivative activates SERCA2a by attenuating the inhibitory effect of phospholamban2017
- Author(s)
  Kaneko Manami、Yamamoto Hisato、Sakai Hiroki、Kamada Yusuke、Tanaka Toshiki、Fujiwara Shuji、Yamamoto Syunsuke、Takahagi Hiroki、Igawa Hideyuki、Kasai Shizuo、Noda Masakuni、Inui Makoto、Nishimoto Tomoyuki
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 814 Pages: 1-8
- DOI
  10.1016/j.ejphar.2017.07.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15203, KAKENHI-PROJECT-17H04033, KAKENHI-PROJECT-15K08235
[Journal Article] Signaling mechanism underlying the promotion of keratinocyte migration by angiotensin II2015
- Author(s)
  Hiroki Sakai, Kenji Matsuura, Yoshie Tanaka, Takeshi Honda, Teruo Nishida, Makoto Inui
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 87 Issue: 2 Pages: 277-285
- DOI
  10.1124/mol.114.096461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25870470, KAKENHI-PROJECT-25670128, KAKENHI-PROJECT-25293062
[Journal Article] Involvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT2R agonist effectively attenuates growth of PDAC grafts in mice.2015
- Author(s)
  Ishiguro S, Yoshimura K, Tsunedomi R, Oka M, Takao S, Inui M, Kawabata A, Wall T, Magafa V, Cordopatis P, Tzakos AG, Tamura M.
- Journal Title
  
  Cancer Biol Ther.
  
  Volume: 16 Issue: 2 Pages: 307-316
- DOI
  10.1080/15384047.2014.1002357
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390317, KAKENHI-PROJECT-25670128, KAKENHI-PROJECT-25861192, KAKENHI-PROJECT-25293062
[Journal Article] Peptide therapies for ocular surface disturbances based on fibronectin-integrin interactions.2015
- Author(s)
  Nishida, T., Inui, M., and Nomizu, M.
- Journal Title
  
  Progress in Retinal and Eye Research
  
  Volume: 47 Pages: 38-63
- DOI
  10.1016/j.preteyeres.2015.01.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670128, KAKENHI-PROJECT-25293062
[Journal Article] Expression of B7-H3, a Potential Factor of Tumor Immune2014
- Author(s)
  Ｎ．Ｍａｅｄａ，　Ｋ．Ｙｏｓｈｉｍｕｒａ，Ｓ．Ｙａｍａｍｏｔｏ
- Journal Title
  
  Ann Surg Oncol
  
  Volume: Epub ahead of print Issue: S4 Pages: 546-554
- DOI
  10.1245/s10434-014-3564-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591907, KAKENHI-PROJECT-25293062, KAKENHI-PROJECT-25670128
[Journal Article] A cell-penetrating phospholamban-specific RNA aptamer enhances Ca2+ transients and contractile function in cardiomyocytes.2014
- Author(s)
  Sakai, H., Ikeda, Y., Honda, T., Tanaka, Y., Shiraishi, K., and Inui, M.
- Journal Title
  
  J. Mol. Cell. Cardiol.
  
  Volume: 76 Pages: 177-185
- DOI
  10.1016/j.yjmcc.2014.09.006
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293062, KAKENHI-PROJECT-25670128, KAKENHI-PROJECT-25870470
[Journal Article] Regulation of adipocyte differentiation of 3T3-L1 cells by PDZRN32013
- Author(s)
  Honda, T., Ishii, A., and Inui, M
- Journal Title
  
  Am. J. Physiol. Cell Physiol
  
  Volume: 304 Issue: 11 Pages: C1091-C1097
- DOI
  10.1152/ajpcell.00343.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390050, KAKENHI-PROJECT-25293062, KAKENHI-PROJECT-25670128
[Journal Article] Regulation of adipocyte differentiation of 3T3-L1 cells by PDZRN3.2013
- Author(s)
  Honda T, Ishii A, Inui M.
- Journal Title
  
  Am J Physiol Cell Physiol.
  
  Volume: 304 Pages: 1091-1097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590323
[Journal Article] Concise synthesis of 2-benzazepine derivatives and their biological activity2012
- Author(s)
  So, M., Kotake, T., Matsuura, K., Inui, M., and Kamimura, A
- Journal Title
  
  J. Org. Chem
  
  Volume: 77 Issue: 8 Pages: 4017-4028
- DOI
  10.1021/jo300380z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390050
[Journal Article] Heart Failure-inducible gene therapy targeting protein phosphatase 1 prevents progressive left ventricular remodeling2012
- Author(s)
  Yosuke Miyazaki
- Journal Title
  
  PLOS ONE
  
  Volume: 7 Issue: 4 Pages: 35875-35875
- DOI
  10.1371/journal.pone.0035875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241, KAKENHI-PROJECT-21590932, KAKENHI-PROJECT-22390050, KAKENHI-PROJECT-22659232, KAKENHI-PROJECT-24390334, KAKENHI-PROJECT-24659640
[Journal Article] Ischemia-reperfusion induces myocardial infarction through mitochondrial Ca^2+ overload2012
- Author(s)
  Shintani-Ishida, K., Inui, M., and Yoshida, K
- Journal Title
  
  J. Mol. Cell. Cardiol
  
  Volume: 53 Issue: 2 Pages: 233-239
- DOI
  10.1016/j.yjmcc.2012.05.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390050, KAKENHI-PROJECT-24659334
[Journal Article] Isoform-specific roles of protein phosphatase 1 catalytic subunits in sarcoplasmic reticulum-mediated Ca(2+) cycling2011
- Author(s)
  Hidekazu Aoyama
- Journal Title
  
  Cardiovasc Res
  
  Volume: 89 Issue: 1 Pages: 79-88
- DOI
  10.1093/cvr/cvq252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390241, KAKENHI-PROJECT-21590932, KAKENHI-PROJECT-22390050
[Journal Article] PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling.2010
- Author(s)
  Honda, T., Yamamoto, H., Ishii, A., and Inui, M.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 21 Issue: 18 Pages: 3269-3277
- DOI
  10.1091/mbc.e10-02-0117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390050
[Patent] ホスホランバン標的修飾RNAアプタマー2012
- Inventor(s)
  乾誠、田中貴絵、酒井大樹、池田安宏、松崎益徳
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2012-028555
- Filing Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-22390050
[Patent] ホスホランバン標的修飾RNAアプタマー2012
- Inventor(s)
  乾誠
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2012-028555
- Filing Date
  2012-02-13
- Data Source
  KAKENHI-PROJECT-22390050
[Patent] 心不全治療薬2008
- Inventor(s)
  乾誠
- Industrial Property Rights Holder
  山口大学
- Industrial Property Number
  2008-032744
- Filing Date
  2008-02-14
- Data Source
  KAKENHI-PROJECT-18659068
[Patent] Method of screening remedy for heart failure2003
- Inventor(s)
  Makoto Inui
- Industrial Property Rights Holder
  Yamaguchi TLO
- Filing Date
  2003-03-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370032
[Presentation] A novel intracellular drug-delivery system specific for cardiomyocytes using RNA aptamer2021
- Author(s)
  Takeshi Honda, Hiroki Sakai, Makoto Inui
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06892
[Presentation] A novel intracellular drug-delivery system specific for cardiomyocytes using RNA aptamer2021
- Author(s)
  Takeshi Honda, Hiroki Sakai, Inui Makoto
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07319
[Presentation] Anti-apoptotic function of PDZRN3 protein in myoblasts2020
- Author(s)
  Takeshi Honda, Ukyo Shinagawa, Yu Mizuno, Yuki Yokosuka, Makoto Inui
- Organizer
  日本薬理学会本会
- Data Source
  KAKENHI-PROJECT-18K06892
[Presentation] 筋芽細胞におけるPDZRN3蛋白質の抗アポトーシス機能2020
- Author(s)
  本田健、品川右京、水野優、横須賀由季、乾誠
- Organizer
  第９３回日本薬理学会
- Data Source
  KAKENHI-PROJECT-17H04033
[Presentation] マスト細胞におけるヒスタミンによる低分子量G蛋白質Rac1及びRac2の活性化はカルシウム/カルモジュリンに依存する2020
- Author(s)
  西尾侑祐、乾誠、倉増敦朗
- Organizer
  第９３回日本薬理学会
- Data Source
  KAKENHI-PROJECT-17H04033
[Presentation] 筋芽細胞におけるPDZRN3蛋白質のアポトーシス制御2019
- Author(s)
  本田健、品川右京、水野優、横須賀由季、乾誠
- Organizer
  第92回日本薬理学会
- Data Source
  KAKENHI-PROJECT-17H04033
[Presentation] PDZRN3蛋白質はサイクリンA2を介して筋芽細胞のアポトーシスを制御する2019
- Author(s)
  本田健、品川右京、水野優、横須賀由季、乾誠
- Organizer
  日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-18K06892
[Presentation] 筋芽細胞におけるPDZRN3蛋白質のアポトーシス制御2019
- Author(s)
  本田健、品川右京、水野優、横須賀由季、乾誠
- Organizer
  第92回日本薬理学会
- Data Source
  KAKENHI-PROJECT-16K15203
[Presentation] トランスグルタミナーゼとヒスタミントランスポーターによるマスト細胞のヒスタミンH4受容体シグナル調節2019
- Author(s)
  倉増敦朗、乾　誠
- Organizer
  第92回日本薬理学会
- Data Source
  KAKENHI-PROJECT-16K15203
[Presentation] トランスグルタミナーゼとヒスタミントランスポーターによるマスト細胞のヒスタミンH4受容体シグナル調節2019
- Author(s)
  倉増敦朗、乾　誠
- Organizer
  第92回日本薬理学会
- Data Source
  KAKENHI-PROJECT-17H04033
[Presentation] PDZRN3蛋白質はサイクリンA2を介して筋芽細胞のアポトーシスを制御する2019
- Author(s)
  本田健、品川右京、水野優、横須賀由季、乾誠
- Organizer
  第７２回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17H04033
[Presentation] PDZRN3 regulates the differentiation of myoblasts into myotubes through Id2-mediated pathway2018
- Author(s)
  Takeshi Honda, Narumi Nakada, Ryoto Nagai, Yuki Yokosuka, Makoto Inui
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Data Source
  KAKENHI-PROJECT-16K15203
[Presentation] PDZRN3 regulates the differentiation of myoblasts into myotubes through Id2-mediated pathway2018
- Author(s)
  Takeshi Honda, Narumi Nakada, Ryoto Nagai, Yuki Yokosuka, Makoto Inui
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Data Source
  KAKENHI-PROJECT-17H04033
[Presentation] PDZRN3蛋白質による筋芽細胞のアポトーシス制御2018
- Author(s)
  本田健、品川右京、水野優、横須賀由季、乾誠
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-16K15203
[Presentation] PDZRN3蛋白質による筋芽細胞のアポトーシス制御2018
- Author(s)
  本田健、品川右京、水野優、横須賀由季、乾誠
- Organizer
  第71回日本薬理学会西南部会
- Data Source
  KAKENHI-PROJECT-17H04033
[Presentation] 心筋細胞内カルシウム輸送調節の分子機構と心不全治療標的2017
- Author(s)
  乾　誠
- Organizer
  第２７回病態生理学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K15203
[Presentation] 心筋細胞内カルシウム輸送調節の分子機構と心不全治療標的2017
- Author(s)
  乾　誠
- Organizer
  第７０回病態生理学会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04033
[Presentation] PDZRN3 regulates myogenic differentiation of myoblasts through modulation of the Id2-mediated pathway2017
- Author(s)
  Takeshi Honda, Narumi Nakada, Ryoto Nagai, Makoto Inui
- Organizer
  第90回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-15K08235
[Presentation] PDZRN3 regulates myogenic differentiation of myoblasts through modulation of the Id2-mediated pathway2017
- Author(s)
  Takeshi Honda, Narumi Nakada, Ryoto Nagai, Makoto Inui
- Organizer
  第90回日本薬理学会本会
- Place of Presentation
  長崎ブリックホール（長崎県）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K08235
[Presentation] IGF-1 promotes epithelial wound healing independently of the IGF-1 receptor via angiotensin II signaling.2016
- Author(s)
  酒井大樹、松浦健二、本田健、西田輝夫、乾　誠
- Organizer
  第８９回日本薬理学会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25670128
[Presentation] Regulation of myogenic differentiation by PDZRN3 through modification of Id2 expression.2016
- Author(s)
  本田健、仲田成美、永井涼人、乾　誠
- Organizer
  第８９回日本薬理学会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] IGF-1 promotes epithelial wound healing independently of the IGF-1 receptor via angiotensin II signaling.2016
- Author(s)
  酒井大樹、松浦健二、本田健、西田輝夫、乾　誠
- Organizer
  第８９回日本薬理学会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] PDZRN3蛋白質によるId2を介した筋芽細胞分化制御2016
- Author(s)
  本田健、仲田成美、永井涼人、乾誠
- Organizer
  第69回日本薬理学会西南部会
- Place of Presentation
  松山大学（愛媛県）
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15K08235
[Presentation] PDZRN3蛋白質によるId2発現調節を介した筋分化制御2016
- Author(s)
  本田健、仲田成美、永井涼人、乾誠
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜パシフィコ（神奈川県）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08235
[Presentation] Regulation of myogenic differentiation by PDZRN3 through modification of Id2 expression2016
- Author(s)
  本田健、仲田成美、永井涼人、乾　誠
- Organizer
  第８９回日本薬理学会
- Place of Presentation
  横浜市（パシフィコ横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25670128
[Presentation] Enhancement of Ca2+ transient and contractile function of cardiomyocytes by phospholamban specific RNA aptamer2015
- Author(s)
  酒井大樹、池田安宏、本田健、田中貴絵、白石宏造、乾　誠
- Organizer
  日本薬理学会
- Place of Presentation
  名古屋（名古屋国際会議場）
- Year and Date
  2015-03-19
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] マスト細胞の走化性におけるトランスグルタミナーゼの役割2015
- Author(s)
  倉増敦朗、武井光、乾　誠
- Organizer
  第６８回日本薬理学会西南部会
- Place of Presentation
  下関市（海峡メッセ下関）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] 皮膚創傷治癒過程におけるIGH-1と知覚神経由来のサブスタンスPとの協調作用のメカニズム2015
- Author(s)
  酒井大樹、松浦健二、本田健、西田輝夫、乾　誠
- Organizer
  第６８回日本薬理学会西南部会
- Place of Presentation
  下関市（海峡メッセ下関）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] 皮膚創傷治癒過程におけるIGH-1と知覚神経由来のサブスタンスPとの協調作用のメカニズム2015
- Author(s)
  酒井大樹、松浦健二、本田健、西田輝夫、乾　誠
- Organizer
  第６８回日本薬理学会西南部会
- Place of Presentation
  下関市（海峡メッセ下関）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25670128
[Presentation] スト細胞の走化性におけるトランスグルタミナーゼの役割2015
- Author(s)
  倉増敦朗、武井光、乾　誠
- Organizer
  第６８回日本薬理学会西南部会
- Place of Presentation
  下関市（海峡メッセ下関）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25670128
[Presentation] ホスホランバンアプタマーによる心筋収縮能およびCa2+トランジェントの増強作用2014
- Author(s)
  酒井大樹、池田安宏、本田健、田中貴絵、白石宏造、乾　誠
- Organizer
  日本薬理学会西南部会
- Place of Presentation
  北九州（産業医科大学ラマツィーニホール）
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] PDZRN3蛋白質によるWntシグナルを介した筋分化制御2014
- Author(s)
  本田健、仲田成美、永井涼人、乾誠
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-24590323
[Presentation] 筋芽細胞株の分化制御におけるPDZRN3蛋白質の役割2014
- Author(s)
  ◯本田健、仲田成美、永井涼人、乾誠
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学（福岡県・北九州市）
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-24590323
[Presentation] PDZRN3蛋白質によるSTAT5bを介した脂肪細胞分化の制御機構2013
- Author(s)
  本田健、石井愛子、乾誠
- Organizer
  第86回日本薬理学会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-24590323
[Presentation] PSD-95 modulates the sensitivity of NR1/NR2A subtype NMDA receptor channels for a NMDA receptor antagonist2007
- Author(s)
  山田康枝、乾誠
- Organizer
  第80回日本薬理学会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] PSD-95 modulates the sensitivity of NR1/NR2A subtype NMDA receptor channels for a NMDA receptor antagonist,MK8012007
- Author(s)
  山田康枝、乾誠
- Organizer
  第50回日本神経化学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] Modulation of NR1/NR2A-subtype NMDA receptor channels by SAP1022007
- Author(s)
  山田康枝、乾誠
- Organizer
  第79回日本薬理学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] Modulation of NR1/NR2A-subtype NMDA receptor channels by SAP1022006
- Author(s)
  Yamada, Y., Inui, M.
- Organizer
  The 79th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] Modulation of the channel activity of NR1/NR2A- and NR1/Nr2B-subtype NMDA receptors by SAP1022006
- Author(s)
  山田康枝、乾誠
- Organizer
  第49回日本神経化学会
- Place of Presentation
  名古屋
- Year and Date
  2006-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] Modulation of NR1/NR2B subtype NMDA receptor channels by SAP-1022005
- Author(s)
  山田康枝、乾誠
- Organizer
  第77回日本薬理学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] 膜貫通型Semaphorin Sema4Cは骨格筋分化に必須である2005
- Author(s)
  高知愛、権藤俊、乾誠
- Organizer
  第77回日本薬理学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] The transmembrane semaphorin Sema4C is required for myoblast differentiation2005
- Author(s)
  Ko, J.-A.and Inui, M.
- Organizer
  The 49th Annual Meeting of Biophysical Society
- Place of Presentation
  Long Beach CA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] MAGUKsファミリー蛋白質SAP102のNR1/NR2BサブタイプNMDA型グルタミン酸受容体に対する効果2004
- Author(s)
  山田康枝、乾誠
- Organizer
  第57回日本薬理学会西南部会
- Place of Presentation
  博多
- Year and Date
  2004-11-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] 新規PDZドメイン蛋白質は骨格筋分化に必須である2004
- Author(s)
  高知愛、木村佳弘、乾誠
- Organizer
  第57回日本薬理学会西南部会
- Place of Presentation
  博多
- Year and Date
  2004-11-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15GS0312
[Presentation] SEK-1005による血管内皮細胞の遊走及び管腔形成促進効果
- Author(s)
  酒井大樹、中島京、岩田博夫、乾　誠
- Organizer
  日本循環薬理学会
- Place of Presentation
  福岡大学（福岡市）
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] 筋芽細胞の筋分化におけるPDZRN3蛋白質の役割
- Author(s)
  本田健、仲田成美、永井涼人、乾誠
- Organizer
  第66回日本薬理学会西南部会
- Place of Presentation
  福岡大学薬学部（福岡）
- Data Source
  KAKENHI-PROJECT-24590323
[Presentation] Regulation of myogenic differentiation by PDZRN3 protein through Wnt signaling.
- Author(s)
  本田　健、仲田成美、永井涼人、乾　誠
- Organizer
  日本薬理学会
- Place of Presentation
  仙台国際センター（仙台市）
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] Promotion of vascular endothelial cell migration and tube formation by SEK-1005.
- Author(s)
  酒井大樹、中島京、岩田博夫、乾　誠
- Organizer
  日本薬理学会
- Place of Presentation
  仙台国際センター（仙台市）
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] 筋芽細胞の筋分化におけるPDZRN3蛋白質の役割
- Author(s)
  本田健、仲田成美、永井涼人、乾　誠
- Organizer
  日本薬理学会西南部会
- Place of Presentation
  福岡大学（福岡市）
- Data Source
  KAKENHI-PROJECT-25293062
[Presentation] STAT5B を介したPDZRN3 の脂肪細胞分化制御
- Author(s)
  本田健、石井愛子、乾誠
- Organizer
  第65回日本薬理学会西南部会
- Place of Presentation
  熊本大学薬学部（熊本市）
- Data Source
  KAKENHI-PROJECT-24590323
[Presentation] Regulation of myogenic differentiation of myoblast by PDZRN3 protein
- Author(s)
  Takeshi Honda, Narumi Nakada, Ryoto Nagai, Makoto Inui
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24590323
[Presentation] Promotion of vascular endothelial cell migration and tube formation by SEK-1005.
- Author(s)
  酒井大樹、中島京、岩田博夫、乾　誠
- Organizer
  日本薬理学会
- Place of Presentation
  仙台国際センター（仙台市）
- Data Source
  KAKENHI-PROJECT-25670128
[Presentation] SEK-1005による血管内皮細胞の遊走及び管腔形成促進効果
- Author(s)
  酒井大樹、中島京、岩田博夫、乾　誠
- Organizer
  日本循環薬理学会
- Place of Presentation
  福岡大学（福岡市）
- Data Source
  KAKENHI-PROJECT-25670128

1. SOBUE Kenji (20112047)

# of Collaborated Projects: 21 results

# of Collaborated Products: 0 results
2. HAYASHI Ken'ichiro (90238105)

# of Collaborated Projects: 16 results

# of Collaborated Products: 0 results
3. TANAKA Junya (70217040)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
4. KIMURA Yoshihiro (90301308)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
5. YAMADA Yasue (00166737)

# of Collaborated Projects: 10 results

# of Collaborated Products: 0 results
6. KO Jie (70314797)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
7. HONDA Takeshi (30457311)

# of Collaborated Projects: 7 results

# of Collaborated Products: 34 results
8. SAKAI Hiroki (40464367)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
9. KURAMASU Atsuo (90302091)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
10. KUZUYA Tsunehiko (80150340)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. TADA Michihiko (90093434)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. HOSHIDA Shiro (80238732)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. TAKAMIYA Kougo (40283767)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. KAMIMURA Akio (30194971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAMBA Keiichi (30346142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Shintnai-Ishida Kaori (50345047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MORITA Tsuyoshi (80403195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. MAYANAGI Taira (20432544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 今田勝巳 (40346143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 柴田克志 (70296565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 今野大治郎 (00362715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 神田啓子

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YOSHIMURA Kiyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 岡正朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 恒富亮一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

INUI Makoto 乾 誠

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Ultrastructural analysis of calcium transport system of cardiac sarcoplasmic reticulum for drug developmentPrincipal Investigator

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Elucidation of the molecular mechanisms by a cyclic peptide, SEK-1005 promotes skin wound healingPrincipal Investigator

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Development of a new drug for heart failure targeting phospholambanPrincipal Investigator

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Analysis of IGF-1 receptor-independent signaling from IGF-1 and its application for drug developmentPrincipal Investigator

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Development of a novel inotropic and lucitorpic agent for treatment of heart failurePrincipal Investigator

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蛋白質結晶構造解析に基づく新たな心不全治療薬デザインのための基礎研究Principal Investigator

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上皮創傷治癒におけるIGF-1の新たな機能の解明と創薬への応用Principal Investigator

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INUI Makoto 乾誠