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SHIRAKATA Masaki  白形 正樹

ORCIDConnect your ORCID iD *help
Researcher Number 70251551
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2007 – 2008: Tokyo Medical and Dental University, 難治疾患研究所, 助教
1994 – 2006: 東京医科歯科大学, 難治疾患研究所, 助手
Review Section/Research Field
Principal Investigator
Molecular biology / Virology / Cell biology / Virology
Except Principal Investigator
Biological Sciences / Functional biochemistry
Keywords
Principal Investigator
EBV / EBウイルス / シグナル伝達 / 複製 / MAPK / BMAL1 / ICP0 / HSV / 潜伏感染 / DNA複製 … More / 転写因子 / transcriptional regulation / replication / 転写制御 / Apoptosis / Cancer / Cell growth / Cell cycle reguration / ゲノム複製 / 細胞周期 / アポトーシス / がん / 細胞増殖 / 細胞周期制御 / Initiation complex / Replication / ORC / 複製開始複合体 / EF-1δ / UL13 / latency / 再活性化 / BMALI / ORFO / ORFP / cell cycle regulation / TRAF / signal transduction / replication licensing / oriP / Epstein-Barr virus / DNA replication / MCM / リン酸化 / 転写調節 / 複製因子 / 筋肉 / DNA結合タンパク質 / 筋細胞 / 分子生物学 / DNA … More
Except Principal Investigator
シグナル伝達 / oriP / preRC / Epstein Barr Virus / cell cycle / EBNA1 protein / ORC complex / MCM complex / in vitro DNA replication / in vitro DNA複製 / in viitro DNA複製 / Epstein Brrr Virus / 細胞周期 / EBNAタンパク質 / ORC複合体 / MCM複合体 / in vitro DNA 複製 / 蛋白質 / EBウイルス / アダプター分子 / Ras-Erk / チロシンキナーゼ / 造血細胞 / 癌 / 免疫学 / 感染症 / ウイルス / チロキシンナーゼ / アダプター / 白血病 Less
  • Research Projects

    (13 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (12 People)
  •  Regulation of Epstein-Barr virus EBNA1 by signal transductionPrincipal Investigator

    • Principal Investigator
      SHIRAKATA Masaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Medical and Dental University
  •  Regulation of Epstein-Barr virus replication by signal transductionPrincipal Investigator

    • Principal Investigator
      SHIRAKATA Masaki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Medical and Dental University
  •  Signal transduction in cell divisionPrincipal Investigator

    • Principal Investigator
      SHIRAKATA Masaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Tokyo Medical and Dental University
  •  蛋白質チロシンリン酸化と癌細胞の増殖応答

    • Principal Investigator
      山梨 裕司
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  Enzymatic analyses of eukaryotic chromosomal DNA replication using the Epstein Barr Virus-derived oriP replicon

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Bcr-Abl下流のrasGAP結合蛋白質Dok及びDok-2と慢性骨髄性白血病

    • Principal Investigator
      YAMANASHI Yuji
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  免疫細胞シグナルによるEpstein-Barrウイルスの抑制機構の研究

    • Principal Investigator
      山梨 裕司
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  In vitro reconstitution of the replication initiation complexPrincipal Investigator

    • Principal Investigator
      SHIRAKATA Masaki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Medical and Dental University
  •  Analysis and the latency of herpes simplex virusPrincipal Investigator

    • Principal Investigator
      SHIRAKATA Masaki, 平井 莞二
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Virology
    • Research Institution
      Tokyo Medical and Dental University
  •  Study on the initiation mechanism of higher eukaryotic DNA replication.Principal Investigator

    • Principal Investigator
      SHIRAKATA Masaki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Medical and Dental University
  •  EBウイルス複製起点における宿主複製開始因子複合体の機能Principal Investigator

    • Principal Investigator
      白形 正樹
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  bHLH型DNA結合転写因子の選択的ダイマー形成の分子機構Principal Investigator

    • Principal Investigator
      白形 正樹
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Medical and Dental University
  •  bHLH型DNA 結合転写因子のダイマー形成特異性を決定するアミノ酸配列規則Principal Investigator

    • Principal Investigator
      白形 正樹
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Molecular biology
    • Research Institution
      Tokyo Medical and Dental University

All 2004 2003

All Journal Article Patent

  • [Journal Article] Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia2004

    • Author(s)
      白形 正樹
    • Journal Title

      Journal of Experimental Medicine 200

      Pages: 1681-1687

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570154
  • [Journal Article] Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia.2004

    • Author(s)
      Tomoharu Yasuda, Masaki Shirakata, Atsushi Iwama, Asuka Ishii, Yasuhiro Ebihara, Mitsujiro Osawa, Kazuho Honda, Hisaaki Shinohara, Katsuko Sudo, Kohichiro Tsuji, Hiromitsu Nakauchi, Yoichiro Iwakura, Hisamaru Hirai, Hideaki Oda, Tadashi Yamamoto, Yuji Yamanashi
    • Journal Title

      Journal of Experimental Medicine 200

      Pages: 1681-1687

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570154
  • [Journal Article] CD40 ligand is a critical effector of Epstein-Barr virus in host cell survival and transformation.2003

    • Author(s)
      Ken-Ichi Imadome, Masaki Shirakata, Norio Shimizu, Shigeaki Nonoyama, Yuji Yamanashi
    • Journal Title

      Proc.Natl.Acad.Sci.USA. 100

      Pages: 7836-7840

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570154
  • [Journal Article] Placental extravillous cytotrophoblasts persistently express class I MHC molecules after human cytomegalovirus infection.2003

    • Author(s)
      Masakazu Terauchi, Hideki Koi, Chikako Hayano, Noriko Toyama-Sorimachi, Hajime Karasuyama, Yuji Yamanashi, Takeshi Aso, Masaki Shirakata
    • Journal Title

      Journal of Virology 77

      Pages: 8187-8195

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570154
  • [Journal Article] CD40 ligand is a critical effector of Epstein-Barr virus in host cell survival and transformation2003

    • Author(s)
      白形 正樹
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 7836-7840

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570154
  • [Journal Article] Placental extravillous cytotrophoblasts persistently express class I MHC molecules after human cytomegalovirus infection.2003

    • Author(s)
      白形 正樹
    • Journal Title

      Journal of Virology 77

      Pages: 8187-8195

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570154
  • [Patent] EBNA1変異体2004

    • Inventor(s)
      白形 正樹
    • Industrial Property Rights Holder
      東京医科歯科大学
    • Industrial Property Number
      2004-316127
    • Filing Date
      2004-10-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570154
  • 1.  YAMANASHI Yuji (40202387)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 2.  KAWAGUCHI Yasushi (60292984)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  MASAI Hisao (40229349)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  SUGATA Naoko (30344071)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  YOU Zhiying (90332270)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MORIYAMA Kenji (00250217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TSURIMOTO Toshiki (30163885)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  樋口 理 (50361720)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  保田 朋波流 (40334429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  平井 莞二 (00100991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TAMAI Katsuyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  ROIZMAN Bernard
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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