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YOSHIMURA Tetsuhiko  吉村 哲彦

ORCIDConnect your ORCID iD *help
Researcher Number 70271517
External Links
Affiliation (based on the past Project Information) *help 2005 – 2006: (財)山形県産業技術振興機構, 研究開発部, 部長
2004: Yamagata Promotional Organization for Industrial Technology, Institute for Life Support Technology, Deputy Director General, 生物ラジカル研究所, 副所長
2003 – 2004: (財)山形県企業振興公社, 生物ラジカル研究所, 副所長
2003 – 2004: 財団法人山形県企業振興公社, 生物ラジカル研究所, 副所長
2003 – 2004: 財団法人山形県産業技術振興機構, 生物ラジカル研究所, 副所長 … More
2001: (財)山形県テクノポリス財団生物ラジカル研究所, 部長
2000 – 2001: (財)山形県テクノポリス財団, 生物ラジカル研究所, 部長
2000: ILST, LAB.OF APPLIED BIOMEDICINAL CHEM.CHIEF SENIOR RESEARCHER, 生物ラジカル研究所, 首席研究員
2000: 山形県生物ラジカル研究所, 主任研究員
2000: 財団法人山形県企業振興公社生物ラジカル研究所, 生物ラジカル研究所, 首席研究員
1999: 財団法人 山形県テクノポリス財団(生物ラジカル研究所), 化学第一研究部, 部長
1999: 財団法人 山形県企業振興公社, 生物ラジカル研究所・化学第一研究部, 部長
1999: ILST, DIVISION OF BIOINORGANIC CHEMISTRY, RESEARCH DIRECTOR, 生物ラジカル研究所・化学第一研究部, 部長
1998: (財)山形県テクノポリス財団(生物ラジカル研究所), 化学第一研究部, 部長
1997: (財)山形県テクノポリス財団生物ラジカル研究所, 化学第一研究部, 部長
1997: ILST,DIVISION OF BIOINORG.CHEM,RES,DIRECTOR, 化学第一研究部, 部長
1996: (財)山形県テクノポリス財団, 生物ラジカル研究所・化学第一研究部, 部長 Less
Review Section/Research Field
Principal Investigator
分離・精製・検出法 / Environmental chemistry / Biological pharmacy / Science and Engineering / 医薬分子機能学
Except Principal Investigator
Circulatory organs internal medicine / Zootechnical science/Grassland science
Keywords
Principal Investigator
生体内一酸化窒素 / 一酸化窒素 / 一酸化窒素(NO) / 電子スピン共鳴 / ENDOGENOUSLY PRODUCED NITRIC OXIDE / NITRIC OXIDE / 鉄錯体 / gastric mucosa / Helicobacter pylori / 胃粘膜 … More / ピロリ菌 / ジニトロシルジチオラト鉄錯体 / DITHIOCARBAMATE / ELECTRON SPIN RESONANCE / IRON COMPLEX / ジチオカルボキシサルコシン / ジチオカルバメート / トラップ / estrogen receptor-dependent repressor / lipopolysaccharide / macrophages / endocrine disrupting chemicals (EDCs) / nitrogenmonoxide (NO) / シグナル伝達系 / 8-ニトログアノシン / エストロゲン受容体阻害剤 / リポポリサッカライド / マクロファージ / 内分泌かく乱物質 / inflammatory cytokine / cyclooxygenase / inducible nitric oxide synthase / nitric oxide / endotoxin / シクロオキシゲナーゼ(COX) / 誘導型NO合成酵素(iNOS) / 炎症性サイトカイン / シクロオキシゲナーゼ(cox) / 誘導型NO合成酵素(iNos) / エンドトキシン / gastro-esophageal junction / nitrate / lipopolysaccharide (LPS) / nitric oxide synthase (NOS) / nitric oxide (NO) / ダブルヘルムホルツコイル / VCO / 誘導型NO合成酵素 / 植物用 / ストレス応答 / フリーラジカル / 携帯型 / in vivo ESR / 酸化還元状態 / ストレス / サクラマス魚卵 / in vivo / オキシデイティブバースト / ストレス応答機構 / 植物 / スピンプローブ法 / ESR / 食道・胃接合部 / 硝酸塩 / リポ多糖(LPS) / 一酸化窒素合成酵素(NOS) / DINITROSYL DITHIOLATO IRON COMPLEX / S-NITROSOTHIOL / NITRATE / NITRITE / CHAMBERED STOMACH / NO IN STOMACH / チャンバート・スタマック法 / チャンバード・スタマック法 / ニトロソチオール / 硝酸イオン / 亜硝酸イオン / チャンバードスタマック法 / 胃内のNO / PHENYL BUTYLNITRONE / N-(DITHIOCARBOXY)SARCOSINE / SPIN TRAP / NFkB / NOトラップ試薬 / 電子スピン共鳴法 / フェニルブチルニトロン / フェニブチルニトロン / スピントラップ / N- (DITHIOCARBOXY) SARCOSINE / TRAP / ジニトロシル鉄錯体 / ジチオカルハメート / ニトロシル鉄錯体 / 画像化 / 捕捉 … More
Except Principal Investigator
reuterin / Lactobacillus reuteri / Reactive oxygen species / FLIP / doxorubicin / heart failure / cardiomyocyte / apoptosis / Fas / WHHL / adenosylcobalamin / pdu operon / glycerol metabolism / probiotics / pdu cluster / pdu(propanediol utilization)オペロン / アデノシルコバラミン / pduオペロン / グリセロール代謝 / ロイテリン / プロバイオティクス / Fas Ligand / reactive oxygen species / doxorubinlin / Fas ligand / post-prandial hyperlipidemia / acute myocardial infarction / atherosclerosis / ischemic heart disease / hypertriglyceridemia / hypercholesterolemia / risk factors / 遺伝様式 / インスリン抵抗性 / 冠動脈疾患 / 複合型高脂血症 / 糖尿病 / 遺伝要因 / 高脂血症 / 遺伝形質 / 食後高脂血症 / 急性心筋梗塞 / 動脈硬化 / 虚血性心臓病 / 高トリグリセリド血症 / 高コレステロール血症 / 危険因子 / ポルフィリン / 反応機構 / モデル / チトクロームC酸化酵素 Less
  • Research Projects

    (12 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (24 People)
  •  The environmental pollution material which assumed NO produced by a cultured cell an index and a food compositionPrincipal Investigator

    • Principal Investigator
      YOSHITAKE Jun, 吉村 哲彦
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Environmental chemistry
    • Research Institution
      Yamagata Promotional Organization for Industrial Technology
  •  Biospin mediated signaling mechanisms in response to extmcellular stressesPrincipal Investigator

    • Principal Investigator
      YOSHIMURA Tetsuhiko, 大矢 博昭
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Yamagata Promotional Organization for Industrial Technology
      Yamagata Public Corporation For the Development Of Industry, Institute Life Support Technology
  •  Molecular mechanism of the reuterin-producing pathway in lactobacilli

    • Principal Investigator
      MORITA Hidetoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Zootechnical science/Grassland science
    • Research Institution
      Azabu University
  •  Physiological action of nitric oxide produced by a stimulation of endotoxin from Helicobacter pylori on gastric mucosaPrincipal Investigator

    • Principal Investigator
      YOSHIMURA Tetsuhiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Yamagata Promotional Organization for Industrial Technology
      Yamagata Public Corporation For the Development Of Industry, Institute Life Support Technology
  •  Contibution of cardiomyocyte apoptosis to development of congestive heart failure

    • Principal Investigator
      YAMAGUCHI Seiji
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      First Department of Internal Medicine, Yamagata University School of Medicine
  •  内因性および外因性配位子を持つニトロシル鉄錯体・蛋白質の生体内生成機構Principal Investigator

    • Principal Investigator
      吉村 哲彦
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Yamagata Public Corporation For the Development Of Industry, Institute Life Support Technology
  •  DETERMINATION OF ENDOGENOUSLY PRODUCED NITRIC OXIDE (NO) IN RAT STOMACH : CYTOPROTECTIVE ROLE OF NOPrincipal Investigator

    • Principal Investigator
      YOSHIMURA Tetsuhiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      医薬分子機能学
    • Research Institution
      INSTITUTE FOR LIFE SUPPORT TECHNOLOGY (ILST), YAMAGATA PUBLIC CORPORATION FOR THE DEVELOPMENT OF INDUSTRY
  •  ESR ANALYSIS AND IN VIVO ACTION OF ENDOGENOUS NITRIC OXIDEPrincipal Investigator

    • Principal Investigator
      YOSHIMURA Tetsuhiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      分離・精製・検出法
    • Research Institution
      INSTITUTE FOR LIFE SUPPORT TECHNOLOGY (ILST)
  •  Determinants of the severity of ischemic heart disease with the burden of multiple risk factors.

    • Principal Investigator
      TOMOIKE Hitonobu
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      First Department of Internal Medicine, Yamagata University School of Medicine
  •  チトクロームC酸化酵素の活性中心モデル錯体の構築とその酸素との反応

    • Principal Investigator
      藤井 浩
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Yamagata Public Corporation For the Development Of Industry, Institute Life Support Technology
  •  抗菌因子NOの捕捉体および標的となる鉄錯体・蛋白質のNOアダクトに関する研究Principal Investigator

    • Principal Investigator
      吉村 哲彦
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Yamagata Public Corporation For the Development Of Industry, Institute Life Support Technology
  •  ANALYSIS OF ENDOGENOUSLY PRODUCED NITRIC OXIDE (NO) EMPLOYING IRON COMPLEXES AS AN NO TRAPPING REAGENT AND PHYSIOLOGICAL STUDY ON NOPrincipal Investigator

    • Principal Investigator
      YOSHIMURA Tetsuhiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      分離・精製・検出法
    • Research Institution
      INSTITUTE FOR LIFE SUPPORT TECHNOLOGY (ILST), YAMAGATA TECHNOPOLIS FOUNDATION

All 2007 2006 2005 2004 2003

All Journal Article Book

  • [Book] Dinitrosyl iron complex in anti-microbial and cytotoxic action of nitrite", In Radicals for Life : the various forms of nitric oxide2007

    • Author(s)
      T.Yoshimura
    • Total Pages
      10
    • Publisher
      Elsevier
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15087212
  • [Book] "Dinitrosyl iron complex in anti-microbial and cytotoxic action of nitrite", In Radicals for Life : the various forms of nitric oxide2007

    • Author(s)
      T.Yoshimura
    • Total Pages
      10
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-15087212
  • [Book] 電子スピン共鳴(ESR, EPR)「生命元素の事典」(桜井弘編)2006

    • Author(s)
      吉村哲彦
    • Total Pages
      6
    • Publisher
      オーム社
    • Data Source
      KAKENHI-PROJECT-15087212
  • [Book] 電子スピン共鳴(ESR,EPR)「生命元素の事典」(桜井弘編)2006

    • Author(s)
      吉村哲彦
    • Total Pages
      6
    • Publisher
      オーム社
    • Data Source
      KAKENHI-PROJECT-17550146
  • [Book] 生体内NOのレドックス種および活性酸素窒素種の反応と活性-最近のシンポ、別冊・医学のあゆみ「酸化ストレスーフリーラジカル医学生物学の最前線Ver.2」2006

    • Author(s)
      吉村哲彦
    • Total Pages
      4
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-17550146
  • [Book] 電子スピンサイエンス&スピンテクノロジー入門、6.2 バイオ電子スピンサイエンス2003

    • Author(s)
      吉村哲彦
    • Total Pages
      10
    • Publisher
      電子スピンサイエンス学会監修
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590087
  • [Journal Article] Dinitrosyl iron complex in anti-microbial and cytotoxic action of nitrite", In Radicals for Life : the various forms of nitric oxide2007

    • Author(s)
      T.Yoshimura
    • Journal Title

      Elsevier 10

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15087212
  • [Journal Article] からだの中のラジカルを電子スピン共鳴(ESR)法で見る-ラジカル画像化の方法と最近の進歩2005

    • Author(s)
      吉村哲彦
    • Journal Title

      化学と教育 53

      Pages: 562-565

    • Data Source
      KAKENHI-PROJECT-17550146
  • [Journal Article] からだの中のラジカルを電子スピン共鳴(ESR)法で見る-ラジカル画像化の方法と最近の進歩2005

    • Author(s)
      吉村哲彦
    • Journal Title

      化学と教育 53

      Pages: 562-565

    • Data Source
      KAKENHI-PROJECT-15087212
  • [Journal Article] Spin Trapping of Nitric Oxide with the Iron-Dithiocarbamate Complex: Chemistry and Biology2004

    • Author(s)
      T.Yoshimura
    • Journal Title

      Antioxid.Redox Signal. 6

      Pages: 639-647

    • Data Source
      KAKENHI-PROJECT-15087212
  • [Journal Article] Lactobacillus reuteri JCM 1112^TとLactobacillus fermentum IFO 3956の比較ゲノム2004

    • Author(s)
      森田英利, 鈴木武人, 加藤行男, 村上賢, 吉村哲彦, 他
    • Journal Title

      生物工学会誌 82

      Pages: 426-427

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15580241
  • [Journal Article] Spin Trapping of Nitric Oxide with the Iron-Dithiocarbamate Complex : Chemistry and Biology2004

    • Author(s)
      T.Yoshimura
    • Journal Title

      Antioxid. Redox Signal. 6

      Pages: 639-647

    • Data Source
      KAKENHI-PROJECT-15590087
  • [Journal Article] Spin Trapping of Nitric Oxide with the Iron-Dithiocarbamate Complex : Chemistry and Biology2004

    • Author(s)
      T.Yoshimura
    • Journal Title

      Antioxid Redox Signal. 6

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590087
  • [Journal Article] Spin trapping of nitric oxide with the iron-dithiocarbamate complex : chemistry and biology2004

    • Author(s)
      T.Yoshimura
    • Journal Title

      Antioxid. Redox Signal. 6

      Pages: 639-647

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15087212
  • [Journal Article] Spin Trapping of Nitric Oxide with the Iron-Dithiocarbamate Complex : Chemistry and Biology2004

    • Author(s)
      T.Yoshimura
    • Journal Title

      Antioxid.Redox Signal., 6

      Pages: 639-647

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590087
  • [Journal Article] Comparative genomics of Lactobacillus reuteri JCM 1112^T and Lactobacillus fermentum IFO 39562004

    • Author(s)
      Morita H., Suzuki T., Murakami M., Kato Y., Yoshimura T., Hattori M.et al.
    • Journal Title

      Journal of Bioscience and Bioengineering 82

      Pages: 426-427

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15580241
  • [Journal Article] Gene clustering for reuterin production in the probiotic bacterium Lactobacillus reuteri JCM 1112^T and its functional importance for viability in the mammalian gastrointestinal tract2004

    • Author(s)
      Morita H., Masaoka T., Horikawa H., Oshima K., Suzuki T., Chinone S., Wada T., Arishima K., Kiuchi A., Sakata R., Shino M., Naito H., Saito Y., Nishita T., Kanemaki N., Takizawa T., Kato Y., Murakami M., Fukuyama M., Kishikawa S., Hisamatsu S., Shiba T., Yoshimura T., Hattori M.
    • Journal Title

      New Challenges in Functional Microbiology and Biotechnology 1

      Pages: 127-132

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15580241
  • [Journal Article] Gene clustering for reuterin production in the probiotic bacterium Lactobacillus reuteri JCM 1112^T and its functional importance for viability in the mammalian gastrointestinal tract2004

    • Author(s)
      Morita H., Masaoka T., Horikawa H., Oshima K., Suzuki T., Chinone S., Wada T., Arishima K., Kiuchi A., Sakata R., Shino M., Naito H., Saito Y., Nishita T., Kanemaki N., Takizawa T., Kato Y., Murakami M., Fukuyama M., Kishikawa S., Hisamatsu S., Shiba T., Yoshimura T., Hattori M.
    • Journal Title

      New Challenges in Functional Microbiology and Biotechnology

      Pages: 127-132

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15580241
  • 1.  FUJII Satoshi (80271518)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  YAMAGUCHI Seij (30239892)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  KASAI Shigenobu (70342730)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TAKEISHI Yasuchika (40272067)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  MORITA Hidetoshi (70257294)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 6.  YOSHITAKE Jun (70414349)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TOMOIKE Hitonobu (90112333)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KUBOTA Isao (30161673)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  OKAZAKI Mitsuyo (20013998)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OOWADA Kazuo (60101010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KATO Katsuaki (30292212)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  SATA Makoto (00280892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  OGATA Tateaki (50091830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  YOKOYAMA Hidekatsu (10281619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KATO Yukio (00224551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 16.  TOMOKAZU Matsuei (70173797)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  右田 たい子 (90159161)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  藤井 浩 (80228957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  中村 秀範 (30240675)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  宮脇 洋 (30261704)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  大矢 博昭 (00025389)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  KISO Yoshinobu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  HENSLEY Kenn
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KOTAKE Yashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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