ISHIGAMI Ken 石神健

… Alternative Names

石神健イシガミケン

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Researcher Number	70292787
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京農業大学, 生命科学部, 教授 2017 – 2018: 東京農業大学, 生命科学部, 教授 2016: 東京大学, 大学院農学生命科学研究科(農学部), 准教授 2012 – 2015: 東京大学, 農学生命科学研究科, 准教授 2010 – 2012: 東京大学, 大学院・農学生命科学研究科, 准教授 … More 2005 – 2007: 東京大学, 大学院・農学生命科学研究科, 講師 2004: 東京大学, 大学院・農学生命科学研究科, 助手 1998 – 2001: 東京大学, 大学院・農学生命科学研究科, 助手 2000: 東大, 農学生命科学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Bioorganic chemistry / Bioproduction chemistry/Bioorganic chemistry / Bioproduction chemistry/Bioorganic chemistry / Basic Section 38040:Bioorganic chemistry-related Except Principal Investigator Basic Section 38050:Food sciences-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Medium-sized Section 37:Biomolecular chemistry and related fields / Bioproduction chemistry/Bioorganic chemistry / Science and Engineering
Keywords	Principal Investigator 天然物化学 / 有機化学 / 有機合成 / 有機合成化学 / セスキテルペン / 立体化学 / 絶対立体配置 / 抗菌物質 / Glabramycin / glabramycin … More / 抗菌活性 / ラジカル環化 / 抗ピロリ菌 / 疎水タグ法 / 生物活性物質 / 環状ポリペプチド / Fusahexin / Surfactin / 疎水性タグ / 環状ペプチド / 天然物有機化学 / 構造改訂 / 構造訂正 / 抗ピロリセスキテルペン / 光学分割 / 抗ピロリ菌活性 / 構造決定 / 天然有機化合物 / Majusculoic acid / 薬剤耐性 / Ma jusculoic acid / 抗腫瘍活性 / Topsentolide / ラジカル環化反応 / 天然生理活性物 / Laurenditerpenol / Tyroscherin / 抗腫瘍物質 / 結合蛋白質 / 光学活性体合成 / 細胞周期阻害剤 / radicicol … More Except Principal Investigator 標的因子 / 食品成分 / プロテアソーム / 健康寿命 / 老化 / 腸管 / 脂質代謝 / 食品成分受容体 / SREBP / スルファラファン / パルミトイル化 / スルフォラファン / 抗肥満 / アルツハイマー病 / ユビキチン / Antitumor Substances / Biotinylated Derivatives / Plant Growth Regulators / Insect Antifeedants / Inhibitors of Cell-Cycle Progression / Structure-Activity Relationship / Synthesis of Optically Active Substances / Irone-Chelator / ムギネ酸 / バイオプローブ / グルコシダーゼ阻害剤 / ファイトシデロフォア / 幼弱ホルモン生合成阻害 / 昆虫摂食阻害物質 / 抗腫瘍物質 / ビオチン誘導体 / 植物成長調節剤 / 昆虫摂食阻害剤 / 細胞周期阻害剤 / 構造活性相関 / 光学活性体合成 / 鉄キレーター / アンダゴニスト / グルタミン酸レセプター / 立体選択的合成 / アンタゴニスト / カイトセファリン / 神経細胞毒性 / グルタミンレセプター / 神経細胞保護 Less

Research on molecular mechanisms of biological regulatory functions by direct and indirect actions of functional food ingredients
- Principal Investigator
  
  井上順
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Tokyo University of Agriculture
プロテアソームによる異常タンパク質分解を活性化して健康寿命を伸ばす
- Principal Investigator
  
  甲斐田大輔
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  University of Toyama
Synthetic study of cyclic polypeptides involved in microbial growth employing hydrophobic tagPrincipal Investigator
- Principal Investigator
  
  石神健
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38040:Bioorganic chemistry-related
- Research Institution
  Tokyo University of Agriculture
Identification of target molecules of functional food ingredients in the intestinal tract and analysis of their effects on the intestinal microflora
- Principal Investigator
  
  Inoue Jun
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Tokyo University of Agriculture
Development of anti-Alzheimer's disease based on a ubiquitin-proteasome activator
- Principal Investigator
  
  KAIDA Daisuke
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  University of Toyama
Synthetic study of natural antibacterial agents for the purpose of determination of their stereochemistryPrincipal Investigator
- Principal Investigator
  
  ISHIGAMI Ken
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Tokyo University of Agriculture
  The University of Tokyo
Synthetic and structural studies of natural antibiotics which have potent activities against drug resistance strainsPrincipal Investigator
- Principal Investigator
  
  ISHIGAMI Ken
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The University of Tokyo
Synthetic and Structural Studies on Bioactive Natural ProductsPrincipal Investigator
- Principal Investigator
  
  ISHIGAMI Ken
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  The University of Tokyo
癌細胞特異的な分子生物学的差異を標的とした抗癌剤の合成研究Principal Investigator
- Principal Investigator
  
  石神健
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  The University of Tokyo
グルタミン酸毒性の発現・抑制機講解明を指向したカイトセファリンの合成と応用研究
- Principal Investigator
  
  WATANABE Hidenori
- Project Period (FY)
  2002 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
魚類成長阻害活性を有するジベレリン応答性加水分解酵素の組織化学的解析Principal Investigator
- Principal Investigator
  
  石神健
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  The University of Tokyo
Synthetic Studies on Optically Active Substances Directed towards the Creation of Novel Functional Materials
- Principal Investigator
  
  KITAHARA Takeshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  The University of Tokyo
細胞周期阻害剤であるRadicicolの合成研究Principal Investigator
- Principal Investigator
  
  石神健
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  The University of Tokyo

[Journal Article] Synthesis, growth inhibitory activity against tumor cells and structure-activity relationship of CGK733 and its analogs2024
- Author(s)
  Inagaki Yuta、Hashimoto Kohki、Wakamori Shinnosuke、Katsuta Ryo、Yajima Arata、Kaida Daisuke、Ishigami Ken
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 88 Issue: 7 Pages: 747-758
- DOI
  10.1093/bbb/zbae047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05063
[Journal Article] Chrysin 7‐<i>O</i>‐β‐<scp>d</scp>‐glucopyranoside increases hepatic low‐density lipoprotein receptor expression through <scp>AMP</scp>‐activated protein kinase activation2023
- Author(s)
  Kaname Naoki、Fujimaki Takahiro、Horikoshi Shotaro、Fujimura Kaito、Kodaka Manami、Wakamori Shinnosuke、Katsuta Ryo、Ishigami Ken、Suzuki Tsukasa、Yamamoto Yuji、Inoue Jun
- Journal Title
  
  FEBS Open Bio
  
  Volume: 13 Issue: 8 Pages: 1447-1458
- DOI
  10.1002/2211-5463.13665
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05063, KAKENHI-PROJECT-21H02145
[Journal Article] Divergent synthesis of ten-membered lactones: Aspinolides C, F, G, H, and I2023
- Author(s)
  Shimizu Ryo、Katsuta Ryo、Takeda Keita、Wakamori Shinnosuke、Kuwahara Shigefumi、Nukada Tomoo、Ishigami Ken
- Journal Title
  
  Tetrahedron
  
  Volume: 139 Pages: 133449-133449
- DOI
  10.1016/j.tet.2023.133449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05063
[Journal Article] Divergent Synthesis of Stachyurin and Casuarinin Focusing on <i>C</i>‐Glycosidic Bond Reactivity2023
- Author(s)
  Kusuki Reina、Murakami Kei、Katsuta Ryo、Ishigami Ken、Wakamori Shinnosuke
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 29 Issue: 41
- DOI
  10.1002/chem.202301096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K05456, KAKENHI-PROJECT-23K05063
[Journal Article] Sulforaphane suppresses the activity of sterol regulatory element-binding proteins (SREBPs) by promoting SREBP precursor degradation2022
- Author(s)
  Miyata Shingo、Kodaka Manami、Kikuchi Akito、Matsunaga Yuki、Shoji Kenta、Kuan Yen-Chou、Iwase Masamori、Takeda Keita、Katsuta Ryo、Ishigami Ken、Matsumoto Yu、Suzuki Tsukasa、Yamamoto Yuji、Sato Ryuichiro、Inoue Jun
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 8715-8715
- DOI
  10.1038/s41598-022-12347-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18342, KAKENHI-PROJECT-20H00408, KAKENHI-PROJECT-21H02145, KAKENHI-PROJECT-20K05845, KAKENHI-PROJECT-20K15473
[Journal Article] First total synthesis of glabramycin B and revision of its relative configuration.2017
- Author(s)
  M. Yamamoto, K. Ishigami, H. Watanabe
- Journal Title
  
  Tetrahedron
  
  Volume: 73 Issue: 23 Pages: 3271-3280
- DOI
  10.1016/j.tet.2017.04.061
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07713
[Journal Article] Synthesis and revision of the relative configuration of glabramycin B2015
- Author(s)
  Ken Ishigami, Masaoki Yamamoto, Hidenori Watanabe
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 56 Issue: 45 Pages: 6290-6293
- DOI
  10.1016/j.tetlet.2015.09.149
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102010, KAKENHI-PROJECT-25450147
[Journal Article] Synthesis of (±)-(Z)-2β-hydroxy-14-hydro-β-santalol employing tandem radical cyclization2015
- Author(s)
  Ken Ishigami, Shinya Yamada, Hidenori Watanabe
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 56 Issue: 42 Pages: 5816-5819
- DOI
  10.1016/j.tetlet.2015.09.011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102010, KAKENHI-PROJECT-25450147
[Journal Article] Synthesis of marine oxylipin topsentolide A1 and its stereoisomers, and determination of the absolute configuration of the natural product2015
- Author(s)
  Ken Ishigami, Munetaka Kobayashi, Motoki Takagi, Kazuo Shin-ya, Hidenori Watanabe
- Journal Title
  
  Tetrahedron
  
  Volume: 71 Issue: 44 Pages: 8436-8443
- DOI
  10.1016/j.tet.2015.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102010, KAKENHI-PROJECT-25450147
[Journal Article] キラリティーを有する天然生理活性物質の合成研究.2015
- Author(s)
  K. Ishigami,T. Kato, S. Wakamori, H. Kageji, H. Watanabe
- Journal Title
  
  Annual Report 2014 (Cryogenic Research Center, The University of Tokyo)
  
  Volume: 6 Pages: 39-44
- NAID
  40020694086
- Data Source
  KAKENHI-PROJECT-25450147
[Journal Article] 最新のトピックス「フローケミストリーでマラリアを克服!?」2012
- Author(s)
  K. Ishigami
- Journal Title
  
  化学
  
  Volume: 67 Pages: 68-69
- Data Source
  KAKENHI-PROJECT-22580115
[Journal Article] Total synthesis of (±)-lysidicin A.2012
- Author(s)
  Y. Ogura, K. Ishigami, H. Watanabe
- Journal Title
  
  Tetrahedron
  
  Volume: 68 Pages: 1723-1728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580115
[Journal Article] 天然物化学における有機合成.2011
- Author(s)
  K. Ishigami
- Journal Title
  
  Annual Report 2010 (Cryogenic Research Center, The University of Tokyo)
  
  Volume: 2 Pages: 32-38
- Data Source
  KAKENHI-PROJECT-22580115
[Journal Article] Determination of the absolute configuration of nodulisporacid A by the concise synthesis of four stereoisomers via three-component reaction and one-pot construction of the framework.2010
- Author(s)
  T. Sumiya, K. Ishigami, H. Watanabe
- Journal Title
  
  Tetrahedron Lett
  
  Volume: 51 Pages: 2765-2767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580115
[Journal Article] Stereoselective Total Synthsis of (±)-Urechitol A2010
- Author(s)
  T. Sumiya, K. Ishigami, H. Watanabe
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 49 Pages: 5527-5528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580115
[Journal Article] Determination of the absolute configuration of marine oxylipin topsentolide A by the synthesis of theenantiomer of the natural product.2010
- Author(s)
  M. Kobayashi, K. Ishigami, H. Watanabe;
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 51(1) Pages: 2762-2764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580115
[Journal Article] Synthesis of (2RS,8R,10R)-YM-193221 and an improved approach to tyroscherin, bioactive natural compounds from Pseudallescheria sp2010
- Author(s)
  R. Katsuta, A. Yajima, K. Ishigami, T. Nukada, H. Watanabe;
- Journal Title
  
  Biosci. Biotechnol. Biochem
  
  Volume: 74 Pages: 2056-2059
- NAID
  10027560555
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22580115
[Journal Article] Stereoselectlve Synthesis of Sch 642305, an Inhibitor of Bacterial DNA Primase.2006
- Author(s)
  K.Ishigami
- Journal Title
  
  Tetrahedron 62巻
  
  Pages: 2224-2230
- Data Source
  KAKENHI-PROJECT-18780085
[Presentation] スルフォラファンによる脂肪滴局在タンパク質PLIN2への作用の解析2024
- Author(s)
  藤枝駿介、小高愛未、正路健太、石神健、鈴木司、山本祐司、井上順
- Organizer
  日本農芸化学会2024年度大会（東京）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] Herbarumin IVの合成研究2024
- Author(s)
  橋本拓郎、勝田亮、若森晋之介、石神健
- Organizer
  日本農芸化学会2024年度大会（東京）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] 11β-HSD1を阻害するメロテルペノイドの合成研究2024
- Author(s)
  加藤光輝、高橋晴太郎、勝田亮、石神健、若森晋之介
- Organizer
  日本農芸化学会2024年度大会（東京）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] スルフォラファンによる脂肪滴局在タンパク質PLIN2への作用の解析2024
- Author(s)
  藤枝駿介、小高愛未、正路健太、石神健、鈴木司、山本祐司、井上順
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-21H02145
[Presentation] Vitroprocine類の合成研究2024
- Author(s)
  丹直輝、中井成美、若森晋之介、勝田亮、石神健
- Organizer
  日本農芸化学会2024年度大会（東京）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] スルフォラファンの新規結合分子の探索とその機能解析2024
- Author(s)
  小高愛未、川平浩太朗、菊地瑛登、正路健太、石神健、鈴木司、山本祐司、井上順
- Organizer
  日本農芸化学会2024年度大会（東京）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] WNT-5A誘導阻害を有する(±)-pochonin Iの合成2024
- Author(s)
  柴田夏帆、鈴木悠生、勝田亮、若森晋之介、矢島新、額田恭郎、石神健
- Organizer
  日本農芸化学会2024年度大会（東京）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] (－)-Decarestrictine Kの合成研究2023
- Author(s)
  上羽隼平, 鈴木隆之介, 勝田亮, 若森晋之介, 石神健
- Organizer
  日本農芸化学会関東支部2023年度大会（川崎）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] 農産物廃棄部位からの機能性成分の同定―サクランボ軸に含まれるChrysin-7-glucosideはLDL受容体発現を上昇させる2023
- Author(s)
  金目尚輝、藤巻貴宏、藤村海人、石神健、鈴木司、山本祐司、井上順
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21H02145
[Presentation] Divergent Synthesis of Aspinolides B-I and Revision of Cremenolide Structure.2023
- Author(s)
  Ryo Katsuta, Ryo Shimizu, Keita Takeda, Shinnosuke Wakamori, Arata Yajima, Shigefumi Kuwahara, Tomoo Nukada, Ken Ishigami
- Organizer
  15th International Kyoto Conference of New Aspects of Organic Chemistry (Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] Development of Unified Synthesis Method of C-Glycosidic Ellagitannins2023
- Author(s)
  Reina Kusuki, Kei Murakami, Ryo Katsuta, Ken Ishigami, Shinnosuke Wakamori
- Organizer
  31st International Conference on Polyphenols (Nantes)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] CGK733類縁体の合成および細胞増殖阻害活性における構造活性相関研究2023
- Author(s)
  稲垣勇汰, 橋本航希, 甲斐田大輔, 若森晋之介, 勝田亮, 石神健
- Organizer
  日本農芸化学会関東支部2023年度大会（川崎）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] SFaNによる前駆体SREBP分解促進作用の解析2023
- Author(s)
  川平浩太朗、小高愛未、石神健、松井伸祐、岩槻健、鈴木司、山本祐司、井上順
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PROJECT-21H02145
[Presentation] フランの開環、再環化を活用した(±)-Gomadalactone 類の合成2023
- Author(s)
  芦崎涼介、勝田亮、若森晋之介、額田恭郎、石神健
- Organizer
  第85回有機合成化学協会関東支部シンポジウム（新潟）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] Synthetic Studies of Gomadalactones.2023
- Author(s)
  Ryosuke Ashizaki, Ryo Katsuta, Shinnosuke Wakamori, Tomoo Nukada, Ken Ishigami
- Organizer
  15th International Kyoto Conference of New Aspects of Organic Chemistry (Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] 架橋基を有する1,4-無水糖の合成研究2023
- Author(s)
  中村康太, 筒井蒼, 勝田亮, 石神健 , 若森晋之介
- Organizer
  第42回日本糖質学会年会（鳥取）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] 計算化学支援によるAspinolide類の網羅的合成と構造に関する研究2023
- Author(s)
  勝田亮, 志水亮, 武田圭太, 若森晋之介, 矢島新, 桑原重文, 額田恭郎, 石神健
- Organizer
  第65回天然有機化合物討論会（東京）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] 抗血小板薬として期待されるsinuxylamide類の合成研究2023
- Author(s)
  中村真夢, 若森晋之介, 勝田亮, 石神健
- Organizer
  日本農芸化学会関東支部2023年度大会（川崎）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] 架橋基導入による立体配座制御を利用した1,4-無水糖の合成研究2023
- Author(s)
  中村康太, 筒井蒼, 勝田亮, 石神健, 若森晋之介
- Organizer
  2023年度東京糖鎖研究会シンポジウム
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] Synthesis, Cell Growth Inhibition and Structure-Activity Relationship of CGK733 analogs.2023
- Author(s)
  Yuta Inagaki, Kouki Hashimoto, Daisuke Kaida, Shinnosuke Wakamori, Ryo Katsuta, Ken Ishigami
- Organizer
  15th International Kyoto Conference of New Aspects of Organic Chemistry (Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] C-グリコシドエラジタンニンであるstachyurinおよびcasuarininの全合成2023
- Author(s)
  楠木怜奈, 村上慧, 勝田亮, 石神健, 若森晋之介
- Organizer
  日本ポリフェノール学会第16回学術集会（つくば）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] Synthesis, Cell Growth Inhibition and Structure-Activity Relationship of CGK733 analogs2023
- Author(s)
  Yuta Inagaki, Kouki Hashimoto, Daisuke Kaida, Shinnosuke Wakamori, Ryo Katsuta, Ken Ishigami
- Organizer
  The 15th International Kyoto Conference on New Aspects of Organic Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18418
[Presentation] Chemical Verification of Axial Chirality Generation in Ellagitannins2023
- Author(s)
  Shinnosuke Wakamori, Rumi Osada, Shintaro Matsumoto, Reina Kusuki, Kei Murakami, Ryo Katsuta, Ken Ishigami
- Organizer
  31st International Conference on Polyphenols (Nantes)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] CGK733類縁体の合成および細胞増殖阻害活性における構造活性相関研究2023
- Author(s)
  稲垣勇汰、橋本航希、甲斐田大輔、若森晋之介、勝田亮、石神健
- Organizer
  日本農芸化学会関東支部2023年度大会
- Data Source
  KAKENHI-PROJECT-23K18418
[Presentation] オキシムを利用したC-グリコシル化反応による天然ポリフェノールの全合成2023
- Author(s)
  楠木怜奈, 村上慧, 勝田亮, 石神健, 若森晋之介
- Organizer
  2023年度東京糖鎖研究会シンポジウム
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] (±)-Pochonin Iの合成2023
- Author(s)
  柴田夏帆、鈴木悠生、勝田亮、若森晋之介、矢島新、額田恭郎、石神健
- Organizer
  第85回有機合成化学協会関東支部シンポジウム（新潟）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] Miyakamide Aの合成2023
- Author(s)
  平本駿, 勝田亮, 若森晋之介, 石神健
- Organizer
  日本農芸化学会関東支部2023年度大会（川崎）
- Data Source
  KAKENHI-PROJECT-23K05063
[Presentation] Sulforaphane promotes Sterol Regulatory Element-binding Proteins (SREBPs) precursor degradation and suppresses the activity of SREBP2022
- Author(s)
  Manami Kodaka, Shingo Miyata, Yuki Matsunaga, Keita Takeda, Ryo Katsuta, Ken Ishigami, Tsukasa Suzuki, Yuji Yamamoto, Ryuichiro Sato, Jun Inoue
- Organizer
  22nd IUCS-ICN
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02145
[Presentation] CGK733がユビキチン-プロテアソーム系によるタンパク質分解を促進する機構の解析2021
- Author(s)
  桒田桜子、伊野部智由、東田千尋、石神健、甲斐田大輔
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K21247
[Presentation] (Z)-2β-Hydroxy-14-hydro-β-santalolの両鏡像体の合成と絶対立体配置の決定2019
- Author(s)
  門脇和生, 山田慎也, 會場翔平, 川崎常臣, 勝田亮, 矢島新, 額田恭郎, 滝川浩郷, 渡邉秀典, 石神健
- Organizer
  日本農芸化学会2019年度大会（東京）
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] Synthesis of (Z)-2β-hydroxy-14-hydro-β-santalol and determination its absolute configuration2018
- Author(s)
  Kazuki Kadowaki, Shinya Yamada, Ryo Katsuta, Arata Yajima, Tomoo Nukada, Hirosato Takikawa, Hidenori Watanabe, Ken Ishigami
- Organizer
  14th International Kyoto Conference on New Aspects of Organic Chemistry (Kyoto)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] JBIR-81及びoryzamide Aの合成2018
- Author(s)
  豊田麻実、勝田　亮、矢島　新、石神　健、額田恭郎
- Organizer
  日本農芸化学会2018年度大会（京都）
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] ウコンより単離された芳香族ビサボラン型セスキテルペンの合成とその香気特性の解明2018
- Author(s)
  白川和泉、矢島　新、勝田　亮、石神　健、額田恭郎
- Organizer
  日本農芸化学会2018年度大会（京都）
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] 腎線維化抑制活性を有するCochlearol Aの合成研究2018
- Author(s)
  鳴瀬和美、勝田　亮、矢島　新、額田恭郎、渡邉秀典、石神　健
- Organizer
  日本農芸化学会2018年度大会（京都）
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] 絶対立体配置決定を目的とした抗ピロリ菌活性セスキテルペンの合成研究2018
- Author(s)
  門脇和生，山田慎也，勝田亮，矢島新，額田恭郎，滝川浩郷，渡邉秀典，石神　健
- Organizer
  第62回香料・テルペンおよび精油化学に関する討論会（長崎）
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] JBIR-81の合成による立体化学の決定2017
- Author(s)
  勝田　亮、豊田麻実、矢島　新、石神　健、額田恭郎
- Organizer
  2017日本農芸化学会関東支部大会（つくば）
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] 天然活性物質の構造改訂と機能解析を目的とした合成研究2017
- Author(s)
  石神　健
- Organizer
  農薬部会第107回セミナー（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] 抗マラリア活性を有する天然化合物Salinipostin Aの合成研究2017
- Author(s)
  藤岡孝亘、石神　健、渡邉秀典
- Organizer
  2017有機合成化学協会関東支部シンポジウム（東京）
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] Trichoderma属糸状菌由来テルペン合成酵素の探索と機能解析2017
- Author(s)
  寺本和矢、石神健、野中健一、塩見和朗、西山真、葛山智久
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学（京都府京都市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K07713
[Presentation] Glabramycin Bの合成と構造訂正2016
- Author(s)
  山本将起、石神健、渡邉秀典
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] クラビゲリン類の両鏡像体の合成2016
- Author(s)
  柿本望、石神健、渡邉秀典
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] Enantioselective syntheses Sch642305 and Glabramycin B, antibacterial 10-membered lactones fused with 4-oxygenated cyclohexanone.2015
- Author(s)
  K. Ishigami, M. Yamamoto, R. Katsuta, H. Watanabe
- Organizer
  PACIFICHEM 2015
- Place of Presentation
  Honolulu（米国）
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] Enantioselective syntheses of Sch642305 and Glabramycin B, antibacterial 10-membered lactones fused with 4-oxygenated cyclohexanone.2015
- Author(s)
  K. Ishigami, M. Yamamoto, R. Katsuta, H. Watanabe
- Organizer
  The 10th International Conference on Cutting-Edge Organic Chemistry in Asia
- Place of Presentation
  Kaohsiung（台湾）
- Year and Date
  2015-11-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] Total Synthesis of Glabramycin B.2015
- Author(s)
  M. Yamamoto, K. Ishigami, H. Watanabe
- Organizer
  The 13th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-13)
- Place of Presentation
  リーガロイヤルホテル京都（京都府・京都市）
- Year and Date
  2015-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] Total Synthesis of (+)-Clavigerin B.2015
- Author(s)
  N. Kakimoto, K. Ishigami, H. Watanabe
- Organizer
  The 13th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-13)
- Place of Presentation
  リーガロイヤルホテル京都（京都府・京都市）
- Year and Date
  2015-11-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] Litseaone Aの合成と構造改訂2014
- Author(s)
  影治秀晃、石神健、渡邉秀典
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス（神奈川県）
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] 三員環を有する生物活性物質の合成研究2014
- Author(s)
  土井悠之介、坂口和彦、石神健、渡邉秀典
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス（神奈川県）
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] 立体化学の決定を目的としたGlabramycinBの合成研究2014
- Author(s)
  山本将起、石神健、渡邉秀典
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス（神奈川県）
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] Plumisclerin Aの四員環架橋構造の構築2013
- Author(s)
  服部弘、石田恭次、石神健、渡邉秀典
- Organizer
  第57回香料・テルペンおよび精油化学に関する討論会
- Place of Presentation
  埼玉大学（埼玉県）
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] 抗菌活性を有するMajusculoic acidの合成研究2013
- Author(s)
  土井悠之介、坂口和彦、石神健、渡邉秀典
- Organizer
  第57回香料・テルペンおよび精油化学に関する討論会
- Place of Presentation
  埼玉大学（埼玉県）
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] GlabramycinBの立体化学決定に向けた合成研究2013
- Author(s)
  山本将起、石神健、渡邉秀典
- Organizer
  日本農芸化学会関東支部2013年度大会
- Place of Presentation
  慶応大学日吉キャンパス（神奈川県）
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] GlabramycinCの立体化学の決定を目的とした合成研究.2013
- Author(s)
  山本将起、石神健、渡邉秀典;
- Organizer
  日本農芸化学会 2013 年度大会
- Place of Presentation
  仙台
- Year and Date
  2013-03-26
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Syntheses of Natural Anti-cancer and Anti-infective Agents, Topsentolide A and (Z)-2 β -Hydroxy-14-hydro- β-santalol.2012
- Author(s)
  K. Ishigami;
- Organizer
  The 13th International Symposium on Natural Product Chemistry
- Place of Presentation
  Karachi, Pakistan
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Efficient synthesis of (±)-(Z)-2 β- hydroxy-14-hydro-β-santalol employing tandem radical cyclization.2012
- Author(s)
  K. Ishigami;
- Organizer
  The 12th International Kyoto Conference on New Aspects of Organic Chemistry (
- Place of Presentation
  Kyoto
- Year and Date
  2012-11-13
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] ラジカル環化反応を用いたサンタロール誘導体の合成研究.2012
- Author(s)
  山田慎也、石神健、渡邉秀典;
- Organizer
  日本農芸化学会 2012 年度大会
- Place of Presentation
  京都
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Synthesis and structure revision of tyroscherin, a growth inhibitor of IGF-1-dependent tumor cells.2010
- Author(s)
  K.Ishigami
- Organizer
  The 5th International Conference on Cutting-Edge Organic Chemistry in Asia
- Place of Presentation
  Hsinchu(台湾)
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] 抗ピロリ菌活性セスキテルペンの合成研究.2010
- Author(s)
  山田慎也、石神健、渡邉秀典
- Organizer
  第54回香料・テルペンおよび精油化学に関する討論会
- Place of Presentation
  甲府
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] ラジカル環化反応を用いた抗ピロリ菌活性セスキテルペンの合成研究2010
- Author(s)
  山田慎也、石神健、渡邉秀典
- Organizer
  日本農芸化学会関東支部2010年度大会
- Place of Presentation
  千葉
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Enantioselective synthesis and determination of the absolute configurations of marine oxylipin topsentolide A_1.2010
- Author(s)
  K.Ishigami
- Organizer
  PACIFICHEM 2010
- Place of Presentation
  Honolulu(米国)
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Synthesis and structure revision of tyroscherin, a growth inhibitor of IGF-1-dependent tumor cells2010
- Author(s)
  K. Ishigami, R. Katsuta, H. Watanabe, T. Kitahara
- Organizer
  The 5th International Conference on Cutting-Edge Organic Chemistry in Asia
- Place of Presentation
  Hsinchu, Taiwan
- Year and Date
  2010-11-09
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Enantioselective synthesis and determination of the absolute configurations of marine oxylipin topsentolide A.2010
- Author(s)
  K. Ishigami, M.
- Organizer
  Kobayashi, H. Watanabe; PACIFICHEM 2010
- Place of Presentation
  Honolulu, USA
- Year and Date
  2010-12-18
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Enantioselective syntheses and determination of the absolute configurations of anti-cancer agents, tyroscherin and topsentolide A.2010
- Author(s)
  K. Ishigami;
- Organizer
  Bangladesh Chemical Congress 2010
- Place of Presentation
  Dhaka, Bangladesh.
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Enantioselective syntheses and determination of the absolute configurations of anti-cancer agents, tyroscherin and topsentolide A_1.2010
- Author(s)
  K.Ishigami
- Organizer
  Bangladesh Chemical Congress 2010
- Place of Presentation
  Dhaka(バングラディシュ)
- Year and Date
  2010-12-12
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] Efficient synthesis of (±)-(Z)-2β-hydroxy-14-hydro-β-santalol employing tandem radical cyclization.
- Author(s)
  K. Ishigami
- Organizer
  The 12th International Kyoto Conference on New Aspects of Organic Chemistry (IKCOC-12)
- Place of Presentation
  リーガロイヤルホテル京都（京都府）
- Data Source
  KAKENHI-PROJECT-22580115
[Presentation] ピペリジンアルカロイドMicrogrewiapine A の合成研究
- Author(s)
  野上恭平、石神健、渡邉秀典
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25450147
[Presentation] Syntheses of Natural Anti-cancer and Anti-infective Agents, Topsentolide A1 and (Z)-2β-Hydroxy-14-hydro-β-santalol.
- Author(s)
  K. Ishigami
- Organizer
  The 13th International Symposium on Natural Product Chemistry
- Place of Presentation
  カラチ（パキスタン）
- Invited
- Data Source
  KAKENHI-PROJECT-22580115

1. WATANABE Hidenori (00202416)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. KAIDA Daisuke (60415122)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. Inoue Jun (70323962)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 東田千尋 (10272931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 伊野部智由 (50568855)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 鎌田春彦 (00324509)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 國澤純 (80376615)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. KITAHARA Takeshi (40087573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 新家一男 (20251481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 飯島香奈絵 (40632500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 渡邊秀典

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 佐藤隆一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 若森晋之介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIGAMI Ken 石神 健

石神 健 イシガミ ケン

Research Projects

Research Products

Co-Researchers

Research on molecular mechanisms of biological regulatory functions by direct and indirect actions of functional food ingredients

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プロテアソームによる異常タンパク質分解を活性化して健康寿命を伸ばす

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Synthetic study of cyclic polypeptides involved in microbial growth employing hydrophobic tagPrincipal Investigator

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Identification of target molecules of functional food ingredients in the intestinal tract and analysis of their effects on the intestinal microflora

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Development of anti-Alzheimer's disease based on a ubiquitin-proteasome activator

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Synthetic study of natural antibacterial agents for the purpose of determination of their stereochemistryPrincipal Investigator

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Synthetic and structural studies of natural antibiotics which have potent activities against drug resistance strainsPrincipal Investigator

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Synthetic and Structural Studies on Bioactive Natural ProductsPrincipal Investigator

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癌細胞特異的な分子生物学的差異を標的とした抗癌剤の合成研究Principal Investigator

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グルタミン酸毒性の発現・抑制機講解明を指向したカイトセファリンの合成と応用研究

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魚類成長阻害活性を有するジベレリン応答性加水分解酵素の組織化学的解析Principal Investigator

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Synthetic Studies on Optically Active Substances Directed towards the Creation of Novel Functional Materials

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細胞周期阻害剤であるRadicicolの合成研究Principal Investigator

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ISHIGAMI Ken 石神健

石神健イシガミケン

[Journal Article] 最新のトピックス「フローケミストリーでマラリアを克服!?」2012