Urano Takeshi 浦野健

… Alternative Names

URANO Takeshi 浦野健

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Researcher Number	70293701
Other IDs
External Links
Affiliation (Current)	2025: 島根大学, 学術研究院医学・看護学系, 特任教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 島根大学, 学術研究院医学・看護学系, 教授 2013 – 2017: 島根大学, 医学部, 教授 2007 – 2011: Shimane University, 医学部, 教授 2006: Nagoya University, Graduate School of Medicine, Associate Professor, 大学院医学系研究科, 助教授 2002 – 2006: Nagoya University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 2001: 名古屋大学, 大学院・医学研究科, 助教授 1998 – 2000: 名古屋大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator General medical chemistry / Pathological medical chemistry / Biological Sciences / Basic Section 54020:Connective tissue disease and allergy-related / Laboratory medicine Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 43020:Structural biochemistry-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / General medical chemistry / Digestive surgery … More / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 49060:Virology-related / Basic Section 55020:Digestive surgery-related / Basic Section 38060:Applied molecular and cellular biology-related / Collagenous pathology/Allergology / General medical chemistry / Structural biochemistry / Surgical dentistry / Biological Sciences Less
Keywords	Principal Investigator Aurora / 細胞周期 / タンパク質分解 / 修飾特異的モノクローナル抗体 / ヒストンH3メチル化 / ヒストンH3リン酸化 / プロテインキナーゼ / イメージング技術 / 脱リン酸化酵素 / がん … More / リン酸化酵素 / 炎症性サイトカイン / バイオ医薬品 / IL-18 / モノクローナル抗体 / 分裂期キナーゼ / 染色体分離 / 染色体リモデリング複合体 / 分子標的 / 細胞分裂 / 染色体 / 中心体 / アンチセンスオリゴDNA / APC / 蛋白質分解 / 造腫瘍能 / Aurora2 / リン酸化 / 難治性炎症疾患 / 抗体治療 / 間質性肺炎 / 抗IL-18活性化断端抗体 / インターロイキン-18 / 活性型 IL-18 測定キット / 潰瘍性大腸炎 / クローン病 / 炎症性腸炎 / 機能阻害抗体 / インターロイキン-18（IL-18） / 臨床検査医学 / 測定キット / IL-1β / 炎症 / calcium / calmodulin / mitotic kinase / Cell cycle / 染色体パッセンジャータンパク質 / オーロラキナーゼ / カルシウム / カルモジュリン / 細胞分裂期キナーゼ / オーロラ / 細胞周期制御 / monoclonal antibodies / image analyzing system / molecular target / cancer / protein degradation / protein phosphatases / protein kinases / cell cycle / アルギニン依存性キナーゼ / ヒストンH3 / オカダ酸 / 動原体 / Aurora-B / non-receptor tyrosine kinase c-src / SH3 domain / EF-hand motif / EGF receptor substrate / Signal Transducer Reps / Small GTPase Ral / Small GTPase Ras / 癌原遺伝子産物c-src / SH3領域 / EF-handモチーフ / EGF受容体基質様領域 / シグナル伝達蛋白Reps / 低分子量G蛋白Ral / 低分子量G蛋白Ras / NCoA-3 / NAC-1 / メチル化 / がん関連転写制御因子 / 核内受容体コアクティベータ / メチル基 / アルギニン残基 / 翻訳後修飾 / ヒストン / WAF1 / p21 / スレオニンキナーゼ / セリン / 基質特異性 / ユビキチン化 / SIAH-1 / EB3 / リン酸化モノクローナル抗体 / p53 / FRET / 中心体局在配列 / GFP融合タンパク質 / タイムラプス観察 / カルモジュリン結合蛋白 / 神経特異的 / 低分子量G蛋白Rin … More Except Principal Investigator RNAスプライシング / 膵がん / neuron / ganglioside / ノックアウト / ニューロン / ガングリオシド / モノクローナル抗体 / IL-18 / 家族性地中海熱 / 立体構造解析 / インフラマソーム / 成人発症スチル病 / 自己炎症 / 補体 / 神経変性 / degeneration / 糖転移酵素 / スフィンゴ糖脂質 / 変性 / 構造解析 / 疾患インタラクトーム / ヒトタンパク質アレイ / タンパク質アレイ / 疾患インララクトーム / 自己炎症疾患 / PTH1型受容体 / 副甲状腺癌 / PTH / Ca / 副甲状腺ホルモン / マクロファージ活性化症候群 / dengue vaccine / 免疫老化 / IL-18 阻害抗体 / 化学療法 / 活性化断端抗体 / インターロイキン-18 / 炎症性サイトカイン / パイロトーシス / 5-フルオロウラシル / 抗IL-18活性化断端抗体 / 炎症性細胞死（パイロトーシス） / ５ーフルオロウラシル（5-FU） / 機能阻害抗体 / インターロイキン-18（IL-18） / エクソンスキップ / エクソンスキップ療法 / 急性骨髄性白血病 / スプライシング / IL-IB / パイソン / 自然免疫 / 単球 / IL-1β / C5a / パイリン / Caspase-1 / 抗体療法 / Interleukin-18 / Pancreatic cancer / 5-フルオロウラシル（5-FU） / 阻害抗体 / 膵臓がん / インターロイキン18（IL-18） / MEFV遺伝子 / 全ゲノム解析 / 血清バイオマーカー / バイオマーカー / X線結晶構造解析 / クロマチン制御 / DNA塩基配列 / ソフトウェア / ヒストン / DNA / エピジェネティクス / ヌクレオソーム / 内科 / IL-1 / カスパーゼ1 / 自己炎症インフラマソーム　カスパーゼ1　IL-1 / インフラソーム / IL-Iβ / バイオ医薬品開発 / がん表面抗原 / 治療法 / 早期診断 / inflammation / raft / nerve / glycolipid / knockout / セロトニン / アセチルコリン / 遺伝子発現 / GD3 / グリア / 炎症 / ラフト / 神経 / 糖脂質 / dorsal root ganglia / purkinje cell / cerebeilum / neuradegeneration / targeting / glysyltransferase / プロキンエ細胞 / 脊髄 / サブトラクション / 後根神経節 / プルキンエ細胞 / 小脳 / ターゲッティング / cloning / knock-out / carbohydrate / トランスフェクション / ジーンノックアウト / リモデリング / スィンゴ糖脂質 / トランスジェニック / クローニング / 糖鎖 / 胆道発癌 / ヘパティクス菌 / ビリス菌 / 胆汁耐性ヘリコバクター属菌 / 胆道発がん / 創薬 / 抗体 / RNAポリメラーゼ / インフルエンザ / Aurora / 分裂期キナーゼ / TRF1 / 卵抽出液 / アフリカツメガエル / M期 / S期 / ヘテロクロマチン / SAHF / がん抑制機構 / HMGA2 / ヒストンH1 / 細胞老化 / ALT / Pot1 / シグナル伝達 / 癌 / テロメレース / クロマチン / テロメア / 染色体 Less

スプライシングにおけるイントロン認識機構と病気発症メカニズムの解明
- Principal Investigator
  
  尾林栄治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Shimane University
Fundamental research on infection prevention using hyaluronic acid nanogel vaccine against dengue virus
- Principal Investigator
  
  ヌグエ・トンミャ・ミャッ
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Shimane University
マクロファージ活性化症候群の新しいマウスモデルの作製と治療応用に向けた研究
- Principal Investigator
  
  杉浦智子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Shimane University
PTH1型受容体に対する阻害抗体を用いた難治性副甲状腺癌の制御
- Principal Investigator
  
  野津雅和
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Shimane University
Comprehensive disease-associated interactome and model mice elucidate diversity and periodicity of the autoinflammatory disease
- Principal Investigator
  
  増本純也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Ehime University
家族性地中海熱の病態における免疫老化の意義を明らかにする研究
- Principal Investigator
  
  古賀智裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
Effects of disease-associated mutations in splicing proteins on RNA splicing
- Principal Investigator
  
  Obayashi Eiji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Shimane University
Fundamental Research Toward Exon Skipping Therapy for Acute Myeloid Leukemia
- Principal Investigator
  
  Sakashita Gyosuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Shimane University
Basic research on antibody therapy against inflammatory cytokine IL-18 for refractory inflammatory diseasesPrincipal Investigator
- Principal Investigator
  
  Urano Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Shimane University
Fundamental study for the treatment of pancreatic cancer by a combination of chemotherapy and IL-18 function-blocking antibody
- Principal Investigator
  
  Tajima Yoshitsugu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Shimane University
Development of novel pancreatic cancer treatment using IL-18 inhibitory antibody
- Principal Investigator
  
  KAMINO Hiroki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Shimane University
パイリンインフラマソーム活性化メカニズムの解明とその制御法の開発
- Principal Investigator
  
  右田清志
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Fukushima Medical University
Development of biomarkers for "early diagnosis" and "realization of precision medicine" of familial Mediterranean fever
- Principal Investigator
  
  Koga Tomohiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nagasaki University
Elucidation of the role of internal DNA sequences in dynamic nucleosome regulation
- Principal Investigator
  
  Kato Hiroaki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Shimane University
Elucidation of the intron recognition mechanism by U2AF1
- Principal Investigator
  
  Obayashi Eiji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Shimane University
Development of refined detection system for mature and active IL-1b family proteinsPrincipal Investigator
- Principal Investigator
  
  Takeshi Urano
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Shimane University
Autoinflammatory biomarker for the new classification of rheumatic disease and identification of therapeutic target
- Principal Investigator
  
  Migita Kiyoshi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Fukushima Medical University
Two types of monoclonal antibodies generated by immunizing mice with MIA-PaCa-2 human pancreatic cancer cell line for diagnostic and therapeutic strategies for pancreatic cancer
- Principal Investigator
  
  Tajima Yoshitsugu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Shimane University
The mechanism analysis of influenza RNA polymerase
- Principal Investigator
  
  Park Sam-Yong
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
Establishment of early diagnosis of enterohepatic Helicobacters infection for prophylaxis and treatment of biliary tract cancers
- Principal Investigator
  
  Tajima Yoshitsugu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Shimane University
Arginine methylation in histone codePrincipal Investigator
- Principal Investigator
  
  URANO Takeshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Shimane University
The elucidation of molecule morbidity of Aurora kinase in oral squamous cell carcinoma, and the application to the medical treatment strategy
- Principal Investigator
  
  KONDO Seiji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Showa University
  Shimane University
The regulatory mechanism of sensor-type transcription factor during mitosisPrincipal Investigator
- Principal Investigator
  
  URANO Takeshi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Shimane University
  Nagoya University
How Chromosomal Aberrations Are Induced by Telomere Dysfunction
- Principal Investigator
  
  ISHIKAWA Fuyuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Mechanisms for the biosignal regulation with glycosphingolipids and their redundancy
- Principal Investigator
  
  FURUKAWA Kouichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Molecular basis of Cancer-specific cell cyclePrincipal Investigator
- Principal Investigator
  
  URANO Takeshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
プロテインキナーゼAuroraによる染色体分配制御の分子基盤Principal Investigator
- Principal Investigator
  
  浦野健
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
プロテインキナーゼAuroraによる染色体均等分離の制御機構とがん治療への応用Principal Investigator
- Principal Investigator
  
  浦野健
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
細胞周期による中心体キナーゼAurora-Aの活性化の時間的・空間的イメージングPrincipal Investigator
- Principal Investigator
  
  浦野健
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
Analysis of in vivo function of glycosphingolipids with glycosylation mutant mice
- Principal Investigator
  
  FURUKAWA Koichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
G2/M期を制御するプロテインキナーゼAuroraの細胞内情報伝達機構Principal Investigator
- Principal Investigator
  
  浦野健
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Molecular mechanism of G2/M Progression by protein kinasesPrincipal Investigator
- Principal Investigator
  
  URANO Takeshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University
神経特異的カルモジュリン結合低分子量G蛋白Rinの新規シグナル伝達系の解析Principal Investigator
- Principal Investigator
  
  浦野健
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nagoya University
The regulation of growth and differentiation signales of nerve cells bar sphingoglycolipids.
- Principal Investigator
  
  FURUKAWA Koichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University
Repsl, which may coordinate a wide variety of the cellular actionsPrincipal Investigator
- Principal Investigator
  
  URANO Takeshi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Nagoya University

[Book] 細胞周期集中マスター北川雅敏編、-レビュー編第1 章細胞周期を制御するリン酸化酵素-2006
- Author(s)
  浦野健
- Publisher
  株式会社羊土社
- Data Source
  KAKENHI-PROJECT-18390083
[Book] 細胞周期集中マスター -第1章細胞周期を制御するリン酸化酵素(レビュー編)-(北川雅敏編)2006
- Author(s)
  浦野健
- Total Pages
  154
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Monoclonal Antibodies Against Mature Interleukin-18 Ameliorate Colitis and Repair Goblet Cell Function2024
- Author(s)
  Mu Jingxi、Maeda Keiko、Ohashi Ayako、Urano Takeshi、Nariai Yuko、Kamino Hiroki、Nakamura Masanao、Yamamura Takeshi、Sawada Tsunaki、Ishikawa Eri、Murate Kentaro、Yamamoto Kenta、Hirose Takashi、Furukawa Kazuhiro、Fujishiro Mitsuhiro、Kawashima Hiroki
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: - Issue: 7 Pages: 2573-2585
- DOI
  10.1007/s10620-024-08453-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08438, KAKENHI-PROJECT-21K08753
[Journal Article] C5a stimulation induces caspase-1 activation and mature IL-1β production in human peripheral blood mononuclear cells2023
- Author(s)
  Fujita Yuya、Matsumoto Haruki、Inada Kenji、Onizawa Michio、Saito Kenji、Sumichika Yuya、Yoshida Shuhei、Temmoku Jumpei、Matsuoka Naoki、Asano Tomoyuki、Sato Shuzo、Machida Takeshi、Migita Kiyoshi
- Journal Title
  
  Immunological Medicine
  
  Volume: 15 Issue: 2 Pages: 1-8
- DOI
  10.1080/25785826.2023.2292665
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08777, KAKENHI-PROJECT-21K07083
[Journal Article] Monoclonal Antibody Against Mature Interleukin-18 Ameliorates Colitis in Mice and Improves Epithelial Barrier Function2023
- Author(s)
  Shuji Ikegami,Keiko Maeda,Takeshi Urano,Jingxi Mu, Masanao Nakamura, Takeshi Yamamura, Tsunaki Sawada, Eri Ishikawa, Kenta Yamamoto, Hisanori Muto,Akina Oishi, Tadashi Iida, Yasuyuki Mizutani, Takuya Ishikawa,;Naomi Kakushima,Kazuhiro Furukawa,Eizaburo Ohno, Takashi Honda, Masatoshi Ishigami,Hiroki Kawashima
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: 12 Issue: 8 Pages: 1353-1366
- DOI
  10.1093/ibd/izad292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15920, KAKENHI-PROJECT-21K08438, KAKENHI-PROJECT-21K08753
[Journal Article] Generation of the novel anti-FXYD5 monoclonal antibody and its application to the diagnosis of pancreatic and lung cancer2023
- Author(s)
  Hotta Takamasa、Nariai Yuko、Kajitani Naoyo、Kadota Kyuichi、Maruyama Riruke、Tajima Yoshitsugu、Isobe Takeshi、Kamino Hiroki、Urano Takeshi
- Journal Title
  
  Biochimie
  
  Volume: - Pages: 160-169
- DOI
  10.1016/j.biochi.2023.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07635, KAKENHI-PROJECT-21K08438, KAKENHI-PROJECT-21K08753
[Journal Article] Generation of antagonistic monoclonal antibodies against the neoepitope of active mouse interleukin (IL)-18 cleaved by inflammatory caspases2022
- Author(s)
  Uchida Yuki、Nariai Yuko、Obayashi Eiji、Tajima Yoshitsugu、Koga Tomohiro、Kawakami Atsushi、Urano Takeshi、Kamino Hiroki
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 727 Pages: 109322-109322
- DOI
  10.1016/j.abb.2022.109322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06049, KAKENHI-PROJECT-21K08438, KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-20K07635, KAKENHI-PROJECT-20K16443
[Journal Article] Extranodal Rosai-Dorfman Disease Involving the Pancreas2022
- Author(s)
  Otaki Satomi、Kawabata Yasunari、Nishi Takeshi、Hayashi Hikota、Iwahashi Teruaki、Maruyama Riruke、Tajima Yoshitsugu
- Journal Title
  
  Pancreas
  
  Volume: 51 Issue: 6 Pages: e89-e91
- DOI
  10.1097/mpa.0000000000002089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08753
[Journal Article] Romidepsin and tamoxifen cooperatively induce senescence of pancreatic cancer cells through downregulation of FOXM1 expression and induction of reactive oxygen species/lipid peroxidation2022
- Author(s)
  Okuni Noriko、Honma Yoshio、Urano Takeshi、Tamura Kenji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: - Issue: 5 Pages: 3519-3529
- DOI
  10.1007/s11033-022-07192-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08438
[Journal Article] Kinetics of Anti-SARS-CoV-2 Antibody Response Following Two Doses of the BNT162b2 mRNA Vaccine: A Japanese Single-Center Primary Care Clinic Report Involving Volunteers and Patients with Autoimmune Disease2022
- Author(s)
  Sugiura Tomoko、Sugiura Hiroaki、Kato Hiroaki、Nariai Yuko、Mizumoto Yuuki、Hanada Kozue、Takahashi Rieko、Hinotubo Yukari、Tanaka Naoko、Sasaki Mutsumi、Eguchi Haruki、Kamino Hiroki、Urano Takeshi
- Journal Title
  
  Infectious Disease Reports
  
  Volume: 15 Issue: 1 Pages: 24-33
- DOI
  10.3390/idr15010003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05505, KAKENHI-PROJECT-20K07635, KAKENHI-PUBLICLY-21H00255
[Journal Article] Pathological eradication of recurrent metastatic renal cell carcinoma with sarcomatoid component by nivolumab plus ipilimumab combination therapy2021
- Author(s)
  Sejima Takehiro、Masago Toshihiko、Yoshida Manabu、Nishi Takeshi、Kawabata Yasunari、Tajima Yoshitsugu、Yumioka Tetsuya、Honda Masashi、Takenaka Atsushi
- Journal Title
  
  International Cancer Conference Journal
  
  Volume: 10 Issue: 4 Pages: 285-289
- DOI
  10.1007/s13691-021-00501-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08753
[Journal Article] New Insights into The Pathogenesis of Intrabile Duct Ectopic Hepatocellular Carcinoma: A Case Report and Review of the Literature2021
- Author(s)
  Nakamura Kosuke、Nishi Takeshi、Hayashi Hikota、Kawabata Yasunari、Araki Asuka、Tajima Yoshitsugu
- Journal Title
  
  Archives of Clinical and Medical Case Reports
  
  Volume: 05 Issue: 03 Pages: 479-482
- DOI
  10.26502/acmcr.96550383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08753
[Journal Article] Phase II feasibility study of adjuvant chemotherapy with docetaxel/cisplatin/S-1 followed by S-1 for stage III gastric cancer2021
- Author(s)
  Hirahara Noriyuki、Matsubara Takeshi、Kaji Shunsuke、Yamamoto Tetsu、Hyakudomi Ryoji、Takai Kiyoe、Ishitobi Kazunari、Uchida Yuki、Tajima Yoshitsugu
- Journal Title
  
  BMC Cancer
  
  Volume: 21 Issue: 1 Pages: 1073-1073
- DOI
  10.1186/s12885-021-08795-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-20K16443
[Journal Article] Chemical map-based prediction of nucleosome positioning using the Bioconductor package nuCpos2021
- Author(s)
  Kato Hiroaki、Shimizu Mitsuhiro、Urano Takeshi
- Journal Title
  
  BMC Bioinformatics
  
  Volume: 22 Issue: 1 Pages: 322-322
- DOI
  10.1186/s12859-021-04240-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-19K05957, KAKENHI-PUBLICLY-19H05264, KAKENHI-PROJECT-21K05505, KAKENHI-PROJECT-21K08438, KAKENHI-PUBLICLY-21H00255
[Journal Article] Sequence-dependent nucleosome formation in trinucleotide repeats evaluated by in vivo chemical mapping2021
- Author(s)
  Koji Katsumata, Yuichi Ichikawa, Tomohiro Fuse, Hitoshi Kurumizaka, Akio Yanagida , Takeshi Urano, Hiroaki Kato, Mitsuhiro Shimizu
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 556 Pages: 179-184
- DOI
  10.1016/j.bbrc.2021.03.155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05957, KAKENHI-PROJECT-18K05556, KAKENHI-PUBLICLY-19H05264, KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-20H00449, KAKENHI-PROJECT-21K05505, KAKENHI-PROJECT-21K08438, KAKENHI-PUBLICLY-21H00255
[Journal Article] A safe and simple technique for nasogastric tube insertion in patients with thoracic esophageal cancer surgery2021
- Author(s)
  Hirahara Noriyuki、Matsubara Takeshi、Kaji Shunsuke、Uchida Yuki、Yamamoto Tetsu、Hyakudomi Ryoji、Takai Kiyoe、Ishitobi Kazunari、Tajima Yoshitsugu
- Journal Title
  
  World Journal of Surgical Oncology
  
  Volume: 19 Issue: 1 Pages: 317-317
- DOI
  10.1186/s12957-021-02428-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-20K16443
[Journal Article] Accurate prediction of severe postoperative complications after pancreatic surgery: POSSUM vs E‐PASS2021
- Author(s)
  Hayashi Hikota、Kawabata Yasunari、Nishi Takeshi、Kishi Takashi、Nakamura Kosuke、Kaji Shunsuke、Fujii Yusuke、Tajima Yoshitsugu
- Journal Title
  
  Journal of Hepato-Biliary-Pancreatic Sciences
  
  Volume: 28 Issue: 2 Pages: 156-164
- DOI
  10.1002/jhbp.839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08753
[Journal Article] Laparoscopic portal branch ligation of the right caudate lobe concomitant with portal vein embolization for planned right hemihepatectomy in advanced hepatobiliary cancers2021
- Author(s)
  Kawabata Yasunari、Hayashi Hikota、Yoshida Rika、Ando Shinji、Nakamura Kosuke、Kishi Takashi、Nishi Takeshi、Nakamura Megumi、Tajima Yoshitsugu
- Journal Title
  
  Langenbeck's Archives of Surgery
  
  Volume: 406 Issue: 3 Pages: 917-926
- DOI
  10.1007/s00423-021-02147-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08753
[Journal Article] A safe, reliable, and efficient robot-assisted port site closure for robot-assisted gastrectomy2021
- Author(s)
  Hirahara Noriyuki、Matsubara Takeshi、Kaji Shunsuke、Uchida Yuki、Yamamoto Tetsu、Hyakudomi Ryoji、Zotani Hitomi、Kawakami Koki、Sasaki Yuhei、Tajima Yoshitsugu
- Journal Title
  
  Annals of Medicine and Surgery
  
  Volume: 71 Pages: 103001-103001
- DOI
  10.1016/j.amsu.2021.103001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08753, KAKENHI-PROJECT-20K16443
[Journal Article] Uric acid-mediated inflammasome activation in IL-6 primed innate immune cells is regulated by baricitinib.2020
- Author(s)
  Temmoku J, Fujita Y, Matsuoka N, Urano T, Furuya MY, Asano T, Sato S, Matsumoto H, Watanabe H, Kozuru H, Yatsuhashi H, Kawakami A, Migita K.
- Journal Title
  
  Mod Rheumatol.
  
  Volume: 30 Issue: 1 Pages: 1-6
- DOI
  10.1080/14397595.2020.1740410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09981, KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-20K08777
[Journal Article] Elucidation of the aberrant 3′ splice site selection by cancer-associated mutations on the U2AF12020
- Author(s)
  Yoshida Hisashi、Park Sam-Yong、Sakashita Gyosuke、Nariai Yuko、Kuwasako Kanako、Muto Yutaka、Urano Takeshi、Obayashi Eiji
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 4744-4752
- DOI
  10.1038/s41467-020-18559-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06086, KAKENHI-PROJECT-20H01007
[Journal Article] Screening of a Panel of Low Molecular Weight Compounds That Inhibit Synovial Fibroblast Invasion in Rheumatoid Arthritis2020
- Author(s)
  Sugiura Tomoko、Kamino Hiroki、Nariai Yuko、Murakawa Yohko、Kondo Masahiro、Kawakami Makoto、Ikeda Noboru、Uchio Yuji、Urano Takeshi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 205 Issue: 12 Pages: 3277-3290
- DOI
  10.4049/jimmunol.1901429
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07635, KAKENHI-PROJECT-20H01007
[Journal Article] Gcn2 eIF2α kinase mediates combinatorial translational regulation through nucleotide motifs and uORFs in target mRNAs2020
- Author(s)
  Chikashige Yuji、Kato Hiroaki、Thornton Mackenzie、Pepper Whitney、Hilgers Madelyn、Cecil Ariana、Asano Izumi、Yamada Haana、Mori Chie、Brunkow Cheyenne、Moravek Carter、Urano Takeshi、Singh Chingakham Ranjit、Asano Katsura
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 48 Issue: 16 Pages: 8977-8992
- DOI
  10.1093/nar/gkaa608
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05556, KAKENHI-PUBLICLY-19H05264
[Journal Article] Nucleus Accumbens-Associated Protein 1 Binds DNA Directly through the BEN Domain in a Sequence-Specific Manner2020
- Author(s)
  Nakayama Naomi、Sakashita Gyosuke、Nagata Takashi、Kobayashi Naohiro、Yoshida Hisashi、Park Sam-Yong、Nariai Yuko、Kato Hiroaki、Obayashi Eiji、Nakayama Kentaro、Kyo Satoru、Urano Takeshi
- Journal Title
  
  Biomedicines
  
  Volume: 8 Issue: 12 Pages: 608-608
- DOI
  10.3390/biomedicines8120608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07307, KAKENHI-PROJECT-18K06086, KAKENHI-PROJECT-18K06152, KAKENHI-PROJECT-20H01007
[Journal Article] How does Hsp90 function in RNAi-dependent heterochromatin assembly?2019
- Author(s)
  Kato H, Okazaki K, Urano T.
- Journal Title
  
  Current Genetics
  
  Volume: 65 Issue: 1 Pages: 87-91
- DOI
  10.1007/s00294-018-0866-0
- NAID
  120006648413
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556
[Journal Article] Chemical map-based prediction of nucleosome positioning using the Bioconductor package nuCpos2019
- Author(s)
  Kato Hiroaki、Shimizu Mitsuhiro、Urano Takeshi
- Journal Title
  
  bioRxiv
  
  Volume: 2019.12.25 Pages: 888305-888305
- DOI
  10.1101/2019.12.25.888305
- Open Access
- Data Source
  KAKENHI-PROJECT-18K05556, KAKENHI-PUBLICLY-19H05264
[Journal Article] Hydroxychloroquine inhibits IL-1β production from amyloid-stimulated human neutrophils.2019
- Author(s)
  Fujita Y, Matsuoka N, Temmoku J, Furuya MY, Asano T, Sato S, Kobayashi H, Watanabe H, Suzuki E, Urano T, Kozuru H, Yatsuhashi H, Koga T, Kawakami A, Migita K.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 21(1) Issue: 1 Pages: 250-250
- DOI
  10.1186/s13075-019-2040-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09981, KAKENHI-PROJECT-17K08983
[Journal Article] Generation and characterization of antagonistic anti-human interleukin (IL)-18 monoclonal antibodies with high affinity: Two types of monoclonal antibodies against full-length IL-18 and the neoepitope of inflammatory caspase-cleaved active IL-18.2019
- Author(s)
  Nariai Y, Kamino H, Obayashi E, Kato H, Sakashita G, Sugiura T, Migita K, Koga T, Kawakami A, Sakamoto K, Kadomatsu K, Nakakido M, Tsumoto K, Urano T.
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 663 Pages: 71-82
- DOI
  10.1016/j.abb.2019.01.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-18K06086, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H05139, KAKENHI-PROJECT-19H00340, KAKENHI-PROJECT-17H06109
[Journal Article] Cancer-related transcription regulator protein NAC1 forms a protein complex with CARM1 for ovarian cancer progression.2018
- Author(s)
  Nakayama N, Sakashita G, Nariai Y, Kato H, Sinmyozu K, Nakayama JI, Kyo S, Urano T, Nakayama K.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 47 Pages: 28408-28420
- DOI
  10.18632/oncotarget.25400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-18K16771, KAKENHI-PROJECT-18H02946
[Journal Article] 2.TH588, an MTH1 inhibitor, enhances phenethyl isothiocyanate-induced growth inhibition in pancreatic cancer cells.2018
- Author(s)
  Ikejiri F, Honma Y, Kasukabe T, Urano T, Suzumiya J.
- Journal Title
  
  Oncol. Lett.
  
  Volume: 15 Pages: 3240-3244
- DOI
  10.3892/ol.2017.7713
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10459, KAKENHI-PROJECT-17K08983
[Journal Article] Expression of aquaporin 3 and 5 as a potential marker for distinguishing dry mouth from Sjögren’s syndrome2018
- Author(s)
  Ichiyama T, Nakatani E, Tatsumi K, Hideshima K, Urano T, Nariai Y, Sekine J.
- Journal Title
  
  Journal of Oral Science
  
  Volume: 60 Issue: 2 Pages: 212-220
- DOI
  10.2334/josnusd.17-0150
- NAID
  130007398371
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983
[Journal Article] Diacylglycerol kinase δ controls down-regulation of cyclin D1 for C2C12 myogenic differentiation2018
- Author(s)
  Sakai Hiromichi、Murakami Chiaki、Matsumoto Ken-ichi、Urano Takeshi、Sakane Fumio
- Journal Title
  
  Biochimie
  
  Volume: 151 Pages: 45-53
- DOI
  10.1016/j.biochi.2018.05.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08271, KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-17H03650, KAKENHI-PROJECT-18J20003
[Journal Article] Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate.2018
- Author(s)
  Ganasen M, Togashi H, Takeda H, Asakura H, Tosha T, Yamashita K, Hirata K, Nariai Y, Urano T, Yuan X, Hamza I, Mauk AG, Shiro Y, Sugimoto H, Sawai H.
- Journal Title
  
  Communications Biology
  
  Volume: 1 Issue: 1 Pages: 120-120
- DOI
  10.1038/s42003-018-0121-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05321, KAKENHI-PROJECT-26220807, KAKENHI-PROJECT-17H03092, KAKENHI-PROJECT-18H02396
[Journal Article] Cotylenin A and tyrosine kinase inhibitors synergistically inhibit the growth of chronic myeloid leukemia cells.2018
- Author(s)
  Ikejiri F, Honma Y, Okada T, Urano T, Suzumiya J.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 52 Pages: 2061-2068
- DOI
  10.3892/ijo.2018.4350
- NAID
  120006645822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08983
[Journal Article] RNAi-dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat-shock molecular chaperones Hsp90 and Mas5.2018
- Author(s)
  Okazaki K, Kato H, Iida T, Shinmyozu K, Nakayama JI, Murakami Y, Urano T.
- Journal Title
  
  Epigenetics & Chromatin
  
  Volume: 11 Issue: 1 Pages: 26-26
- DOI
  10.1186/s13072-018-0199-8
- NAID
  120006651232
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-18K05556, KAKENHI-PROJECT-17H03713
[Journal Article] Analysis of the oligomeric states of nucleophosmin using size exclusion chromatography.2018
- Author(s)
  Sakashita G, Kiyoi H, Naoe T, Urano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 4008-4008
- DOI
  10.1038/s41598-018-22359-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PROJECT-17K09921
[Journal Article] Parallel mapping with site-directed hydroxyl radicals and micrococcal nuclease reveals structural features of positioned nucleosomes in vivo.2017
- Author(s)
  Fuse T, Katsumata K, Morohoshi K, Mukai Y, Ichikawa Y, Kurumizaka H, Yanagida A, Urano T, Kato H, Shimizu M.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 10 Pages: e0186974-e0186974
- DOI
  10.1371/journal.pone.0186974
- NAID
  120006539368
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983, KAKENHI-PLANNED-25116002, KAKENHI-PROJECT-17H01408
[Journal Article] Japanese apricot extract (MK615) potentiates bendamustine-induced apoptosis via impairment of the DNA damage response in lymphoma cells.2017
- Author(s)
  Inoue M, Honma Y, Urano T, Suzumiya J.
- Journal Title
  
  Oncol Lett.
  
  Volume: 14 Issue: 1 Pages: 792-800
- DOI
  10.3892/ol.2017.6219
- NAID
  120006645824
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983
[Journal Article] The 19S proteasome is directly involved in the regulation of heterochromatin spreading in fission yeast.2017
- Author(s)
  Seo HD, Choi Y, Kim M, Kang K, Urano T, Lee D.
- Journal Title
  
  J Biol Chem.
  
  Volume: 292 Issue: 41 Pages: 17144-17155
- DOI
  10.1074/jbc.m117.790824
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08983
[Journal Article] Precise epitope determination of the anti-vimentin monoclonal antibody V9.2017
- Author(s)
  Tomiyama L, Kamino H, Fukamachi H, Urano T.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 16 Issue: 4 Pages: 3917-3921
- DOI
  10.3892/mmr.2017.7102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08983
[Journal Article] A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit.2015
- Author(s)
  Yoshida H, Park S-Y, Oda T, Akiyoshi T, Sato M, Shirouzu M, Tsuda K, Kuwasako K, Unzai S, Muto Y, Urano T, Obayashi E.
- Journal Title
  
  Genes Dev.
  
  Volume: 29 Issue: 15 Pages: 1649-1660
- DOI
  10.1101/gad.267104.115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06980, KAKENHI-PROJECT-15K06982, KAKENHI-PROJECT-15K18499, KAKENHI-PUBLICLY-26116519, KAKENHI-PROJECT-25291016, KAKENHI-PROJECT-25291037
[Journal Article] Rappsilber J and Allshire RC.: Raf1 is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification2012
- Author(s)
  Buscaino A, White S, Houston D, Simmer F, Alves F, Diyora PT, Urano T, Bayne E
- Journal Title
  
  PLoS Genet.
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] DNA : RNA hybrid formation mediates RNAi-directed heterochromatin formation2012
- Author(s)
  Nakama M, Kawakami K, Kajitani T, Urano T and Murakami Y
- Journal Title
  
  Genes Cells
  
  Volume: 17 Pages: 218-233
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Murakami Y and Nakayama J-I.: Heterochromatin protein 1 homologue Swi6 acts in concert with Ers1 to regulate RNAi-directed heterochromatin assembly2012
- Author(s)
  Hayashi A, Ishida M, Kawaguchi R, Urano T
- Journal Title
  
  Proc. Natl Acad. Sci. USA
  
  Volume: 109 Pages: 6159-6164
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells2012
- Author(s)
  Inoko A, Matsuyama M, Goto H, Ohmuro-Matsuyama Y, Hayashi Y, Enomoto M, Ibi M, Urano T, Yonemura S, Kiyono T, Izawa I and Inagaki M.
- Journal Title
  
  J. Cell Biol.
  
  Volume: 197 Pages: 391-405
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] pp-GalNAc-T13 induces high metastatic potential of murine Lewis lung cancer by generating trimeric Tn antigen2012
- Author(s)
  Matsumoto Y, Zhang Q, Akita K, Nakada H, Hamamura K, Tokuda N, Tsuchida A, Matsubara T, Hori T, Okajima T, Furukawa K, Urano T and Furukawa K
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 419 Pages: 7-13
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] The nuclear scaffold protein SAF-A is required for kinetochore-microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles2011
- Author(s)
  Ma N, Matsunaga S, Morimoto A, Sakashita G, Urano T, Uchiyama S and Fukui K
- Journal Title
  
  J. Cell Sci
  
  Volume: 124 Pages: 394-404
- NAID
  120006994997
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis2011
- Author(s)
  Ban R, Nishida T and Urano T
- Journal Title
  
  Genes Cells
  
  Volume: 16 Pages: 652-669
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Preparation, characterization and properties of novel covalently surface-functionalized zinc oxide nanoparticles2010
- Author(s)
  Sato M, Harada H, Morito S, Fujita Y, Shimosaki S, Urano T and Nakamura M
- Journal Title
  
  Appl. Surf. Sci
  
  Volume: 256 Pages: 4497-4501
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast2010
- Author(s)
  Simmer F, Buscaino A, Kos-Braun IC, Kagansky A, Boukaba A, Urano T, Kerr AR and Allshire RC
- Journal Title
  
  EMBO Rep
  
  Volume: 11 Pages: 112-118
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Glycosylphosphatidylinositol-anchored arginine-specific ADP-ribosyltransferase7.1(Art7.1) on chicken B cells: the possible role of Art7 in B cell receptor signalling and proliferation.2009
- Author(s)
  Terashima M, Takahashi M, Shimoyama M,Tanigawa Y, Urano T and Tsuchiya M
- Journal Title
  
  Mol Cell Biochem 320
  
  Pages: 470-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity2009
- Author(s)
  Arimura N, Hattori A, Kimura T, Nakamuta SI, Funahashi Y, Hirotsune S, Furuta K, Urano T, Toyoshima YY, Kaibuchi K
- Journal Title
  
  J Neurochem
  
  Volume: 111 Pages: 380-390
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases2009
- Author(s)
  Ban R, Matsuzaki H, Akashi T, Sakashita G, Taniguchi H, Park S-Y, Tanaka H, Furukawa K and Urano T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 284 Pages: 28367-28381
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Synthetic heterochromatin bypasses RNAi and centromeric repeats to establish functional centromeres2009
- Author(s)
  Kagansky A, Folco HD, Almeida R, Pidoux AL, Boukaba A, Simmer F, Urano T, Hamilton GL and Allshire RC
- Journal Title
  
  Science
  
  Volume: 324 Pages: 1716-1719
- Data Source
  KAKENHI-PROJECT-21390081
[Journal Article] Phosphorylation of Swi6/HP1 regulates transcriptional gene silencing at heterochromatin.2009
- Author(s)
  Shimada A, Dohke K, Sadaie M, Shinmyozu K,Nakayama J, Urano T and Murakami Y
- Journal Title
  
  Genes Dev. 23
  
  Pages: 18-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Cdc2p controls the forkhead transcription factor Fkh2p by phosphorylation during sexual differentiation in fission yeast.2008
- Author(s)
  Shimada M, Yamada-Namikawa C,Murakami-Tonami Y, Yoshida T, Nakanishi M, Urano T, and Murakami H
- Journal Title
  
  EMBO J 27
  
  Pages: 132-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Heterochromatin and RNAi Are Required to Establish CENP-A Chromatin at Centromeres.2008
- Author(s)
  Folco HD, Pidoux AL, Urano T, and Allshire RC
- Journal Title
  
  Science 319
  
  Pages: 94-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Fission yeast chromatin assembly factor 1 assists in the replication-coupled maintenance of heterochromatin.2008
- Author(s)
  Dohke K, Miyazaki S, Tanaka K, Urano T,Grewal SI and Murakami Y
- Journal Title
  
  Genes Cells 13
  
  Pages: 1027-1043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Heterochromatin and RNAi are required to establish CENP-A chromatin at centromeres.2008
- Author(s)
  Folco, H.D., Pidoux, A.L., Urano, T., Allshire, R.C.
- Journal Title
  
  Science 319
  
  Pages: 94-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation.2008
- Author(s)
  Kondo Y, Shen L, Cheng AS, Ahmed S,Boumber Y, Charo C, Yamochi T, Urano T,Furukawa K, Kwabi-Addo B, Gold DL,Sekido Y, Huang TH and Issa JP
- Journal Title
  
  Nature Genet 40
  
  Pages: 741-750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin.2007
- Author(s)
  Trewick SC, Minc E, Antonelli R, Urano T,and Allshire RC
- Journal Title
  
  EMBO J. 26
  
  Pages: 4670-4682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties.2007
- Author(s)
  Nakashima H, Hamamura K, Houjou T,Taguchi R, Yamamoto N, Mitsudo K,Tohnai I, Ueda M, Urano T, Furukawa K,Furukawa K
- Journal Title
  
  Cancer Sci 98
  
  Pages: 512-520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Role of DNA methylation and histone H3 Lysine 27 methylation in tissue-specific imprinting of mouse Grb10.2007
- Author(s)
  Yamasaki-Ishizaki Y, Kayashima T,Mapendano CK, Soejima H, Ohta T,Masuzaki H, Kinoshita A, Urano T,Yoshiura KI, Matsumoto N, Ishimaru T,Mukai T, Niikawa N and Kishino T
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 732-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Analysis of the role of Aurora B on the chromosomal targeting of condensin I.2007
- Author(s)
  Takemoto A, Murayama A, Katano M,Urano T, Furukawa K, Yokoyama S,Yanagisawa J, Hanaoka F and Kimura K
- Journal Title
  
  Nucleic Acids Res 35
  
  Pages: 2403-2412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Gene amplification and overexpression of PRDM14 in breast cancers.2007
- Author(s)
  Nishikawa N, Toyota M, Suzuki H,Honma T, Fujikane T, Ohmura T,Nishidate T, Ohe-Toyota M, Maruyama R,Sonoda T, Sasaki Y, Urano T, Imai K,Hirata K, and Tokino T
- Journal Title
  
  Cancer Res 67
  
  Pages: 9649-9657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Nucleophosmin (NPM): A versatile molecule associated with hematological malignancies.2006
- Author(s)
  Naoe T, Suzuki T, Kiyoi H and Urano T
- Journal Title
  
  Cancer Sci 97
  
  Pages: 963-969
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Complex formation of Plk1 and INCENP required for metaphase-anaphase transition.2006
- Author(s)
  Goto H, Kiyono T, Tomono Y, Kawajiri A, Urano T, Furukawa K, Nigg EA, Inagaki M.
- Journal Title
  
  Nature Cell Biol. 8
  
  Pages: 180-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590222
[Journal Article] Phospho-regulation of human Protein Kinase Aurora-A: Analysis using anti-phospho-Thr288 monoclonal antibodies.2006
- Author(s)
  Ohashi S, Sakashita G, Ban R, Nagasawa M, Matsuzaki H, Murata Y, Taniguchi H,Shima H, Furukawa K and Urano T
- Journal Title
  
  Oncogene 25
  
  Pages: 7691-7702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Expression profile of LIT1/KCNQ1OT1 and epigenetic status at the KvDMR1 in colorectal cancers.2006
- Author(s)
  Nakano S, Murakami K, Meguro M, Soejima H, Higashimoto K, Urano T,Kugoh H, Mukai T, Ikeguchi M and Oshimura M
- Journal Title
  
  Cancer Sci 97
  
  Pages: 1147-1154
- NAID
  10019376824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Metastatic potential of mouse Lewis lung cancer cells is regulated via ganglioside GM1 by modulating the matrix metalloprotease-9 localization in lipid rafts.2006
- Author(s)
  Zhang Q, Furukawa K, Chen HH, Sakakibara T, Urano T and Furukawa K
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 18145-18155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Nucleophosmin: a versatile molecule associated with hematological malignancies.2006
- Author(s)
  Naoe, T., Suzuki, T., Kiyoi, H., Urano, T.
- Journal Title
  
  Cancer Sci 97
  
  Pages: 963-969
- NAID
  10019377506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] Complex formation of Plk1 and INCENP required for metaphase-anaphase transition.2006
- Author(s)
  Goto H, Kiyono T, Tomono Y, Kawajiri A, Urano T, Furukawa K, Nigg EA and Inagaki M
- Journal Title
  
  Cell Biol 8
  
  Pages: 180-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Complex formation of Plk1 and INCENP required for metaphase-anaphase transition.2006
- Author(s)
  Goto, H., Kiyono, T., Tomono, Y., Kawajiri, A., Urano, T., Furukawa, K., Nigg, EA., Inagaki M.
- Journal Title
  
  Nat.Cell Biol. 8
  
  Pages: 180-187
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins.2006
- Author(s)
  Okuda T, Tokuda N, Numata S, Ito M, Ohta M, Kawamura K, Wiels J, Urano T, Tajima O, Furukawa K and Furukawa K
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 10230-10235
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390083
[Journal Article] Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.2005
- Author(s)
  Hamamura K, Furukawa K, Hayashi T, Hattori T, Nakano J, Nakashima H, Okuda T, Mizutani H, Hattori H, Ueda M, Urano T, Lloyd KO, Furukawa K.
- Journal Title
  
  Proc Natl Acad Sci USA 102
  
  Pages: 11041-11046
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590222
[Journal Article] Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes : identification of an aneuploidy-promoting property.2005
- Author(s)
  Nguyen HG, Chinnappan D, Urano T, Ravid K.
- Journal Title
  
  Mol Cell Biol 25
  
  Pages: 4977-4992
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590222
[Journal Article] Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres.2005
- Author(s)
  Kanoh, J., Sadaie, M., Urano, T., Ishikawa, F.
- Journal Title
  
  Curr Biol 15
  
  Pages: 1808-1819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air.2005
- Author(s)
  Yamasaki Y, Kayashima T, Soejima H, Kinoshita A, Yoshiura KI, Matsumoto N, Ohta T, Urano T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Kishino T.
- Journal Title
  
  Hum Mol Genet 14
  
  Pages: 2511-2520
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590222
[Journal Article] Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air.2005
- Author(s)
  Yamasaki, Y., Kakashima, T., Soejima, H., Kinoshi ta, A., Yoshiura, K., Matsumoto, N., Ohta, T., Urano, T., Masuzaki, H., Ishimaru, T., Mukai, T., Niikawa, N., Kishino, T.
- Journal Title
  
  Hum.Mol.Genet. 14
  
  Pages: 2511-2520
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] RNA polymerase II is required for RNAi-dependent heterochromatin assembly.2005
- Author(s)
  Kato, H., Goto, D.B., Martienssen, R.A., Urano, T., Furukawa, K., Murakami, Y.
- Journal Title
  
  Science 309
  
  Pages: 467-469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes : identification of an aneuploidy-promoting property.2005
- Author(s)
  Nguyen, HG., Chinnappan, D., Urano, T., Ravid, K.
- Journal Title
  
  Mol.Cell Biol. 25
  
  Pages: 4977-4992
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] RNA polymerase II is required for RNAi-dependent heterochromatin assembly.2005
- Author(s)
  Kato H, Goto DB, Martienssen RA, Urano T, Furukawa K, Murakami Y.
- Journal Title
  
  Science 309
  
  Pages: 467-469
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590222
[Journal Article] Telomere binding protein Taz1 establishes Swi6 heterochromatin independently of RNAi at telomeres.2005
- Author(s)
  Kanoh J, Sadaie M, Urano T, Ishikawa F.
- Journal Title
  
  Curr.Biol. 15
  
  Pages: 1808-1819
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590222
[Journal Article] Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells.2005
- Author(s)
  Hamamura, K., Furukawa, K., Hayashi, T., Hattori, T., Nakano, J., Nakashima, H., Okuda, T., Mizutani, H., Hattori, H., Ueda, M., Urano, T., Lloyd, KO., Furukawa, K
- Journal Title
  
  Proc.Natl.Acad.Sci. U S A. 102
  
  Pages: 11041-11046
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] RNA polymerase II is required for RNAi-dependent heterochromatin assembly.2005
- Author(s)
  Kato, H., Goto, DB., Martienssen, RA., Urano, T., Furukawa, K., Murakami, Y.
- Journal Title
  
  Science 309
  
  Pages: 467-469
- Data Source
  KAKENHI-PROJECT-17013043
[Journal Article] Telomere-Binding Protein Taz1 Establishes Swi6 Heterochromatin Independently of RNAi at Telomeres.2005
- Author(s)
  Kanoh, J., Sadaie, M., Urano, T., Ishikawa F.
- Journal Title
  
  Curr.Biol. 15
  
  Pages: 1808-1819
- Data Source
  KAKENHI-PROJECT-17013043
[Patent] 間質性肺疾患の治療薬2024
- Inventor(s)
  川上純、古賀智裕、浦野健、成相裕子、他
- Industrial Property Rights Holder
  川上純、古賀智裕、浦野健、成相裕子、他
- Industrial Property Rights Type
  特許
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-21K08438
[Patent] 活性型ＩＬ－１８検出キット、及び検査方法2023
- Inventor(s)
  浦野健、加美野宏樹、成相裕子、川上純、古賀智裕、他
- Industrial Property Rights Holder
  浦野健、加美野宏樹、成相裕子、川上純、古賀智裕、他
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2023-195765
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-21K08438
[Patent] ワクチン組成物2021
- Inventor(s)
  勝又徹、浦野健、成相裕子、加美野宏樹、秋吉一成、他
- Industrial Property Rights Holder
  旭化成（株）、島根大学、京都大学、三重大学、長崎大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-559206
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K08438
[Patent] 活性型インターロイキンー１８タンパク質のネオエピトープを認識する抗体、及びその応用2021
- Inventor(s)
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Holder
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20K07635
[Patent] 活性型インターロイキンー１８タンパク質のネオエピトープを認識する抗体、及びその応用2021
- Inventor(s)
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Holder
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-20K07635
[Patent] 活性型インターロイキンー１８タンパク質のネオエピトープを認識する抗体、及びその応用2021
- Inventor(s)
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Holder
  株式会社 mAbProtein
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-21K08438
[Patent] ワクチン組成物2021
- Inventor(s)
  加美野宏樹、成相裕子、浦野健（他６人）
- Industrial Property Rights Holder
  旭化成（株）、島根大学、京都大学、三重大学、長崎大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-204470
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K07635
[Patent] 活性型インターロイキンー１８タンパク質のネオエピトープを認識する抗体、及びその応用2020
- Inventor(s)
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Holder
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-559206
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K07635
[Patent] 検出感度の高いインターロイキンー１８タンパク質に対する抗体およびその応用2019
- Inventor(s)
  浦野健、成相裕子、尾林栄治、加美野宏樹
- Industrial Property Rights Holder
  株式会社 mAbProtein
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17K08983
[Patent] 活性型インターロイキンー１８タンパク質のネオエピトープを認識する抗体、及びその応用2019
- Inventor(s)
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Holder
  株式会社 mAbProtein
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17K08983
[Patent] 活性型インターロイキンー１８タンパク質のネオエピトープを認識する抗体、及びその応用2018
- Inventor(s)
  浦野健、成相裕子、加美野宏樹、尾林栄治
- Industrial Property Rights Holder
  国立大学法人島根大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-226667
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K08983
[Patent] 検出感度が向上した、炎症性サイトカイン IL-18 タンパク質に対する新規抗体およびその応用2018
- Inventor(s)
  浦野健、成相裕子、尾林栄治、加美野宏樹
- Industrial Property Rights Holder
  国立大学法人島根大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-072006
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K08983
[Patent] インフルエンザウイルスのRNA依存性RNAポリメラーゼのPB2サブユニットに対するモノクローナル抗体2014
- Inventor(s)
  朴三用、浦野健、杉山佳奈子
- Industrial Property Rights Holder
  朴三用、浦野健、杉山佳奈子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-068824
- Filing Date
  2014-03-28
- Acquisition Date
  2015-10-13
- Data Source
  KAKENHI-PROJECT-25291016
[Patent] インフルエンザウイルスのＲＮＡ依存性ＲＮＡポリメラーゼのＰＢ２サブユニットに対するモノクローナル抗体2014
- Inventor(s)
  朴三用、杉山佳奈子、成相裕子、浦野健
- Industrial Property Rights Holder
  朴三用、杉山佳奈子、成相裕子、浦野健
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-068824
- Filing Date
  2014-04-10
- Data Source
  KAKENHI-PROJECT-25291016
[Patent] 新規モノクローナル抗体、及びそのタグ抗体としての利用2012
- Inventor(s)
  浦野健、辰巳香澄、関根浄治
- Industrial Property Rights Holder
  島根大学
- Filing Date
  2012-03-13
- Overseas
- Data Source
  KAKENHI-PROJECT-21390081
[Patent] 新規モノクローナル抗体、及びそのタグ抗体としての利用2012
- Inventor(s)
  浦野健、辰巳香澄、関根浄治
- Industrial Property Rights Holder
  島根大学
- Filing Date
  2012-03-13
- Overseas
- Data Source
  KAKENHI-PROJECT-21390081
[Patent] 物質相互作用をリアルタイムに可視化する技術2011
- Inventor(s)
  岡崎宏亮、成相裕子、加藤太陽、浦野健
- Industrial Property Rights Holder
  島根大学
- Industrial Property Number
  2011-076772
- Filing Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21390081
[Patent] 新規モノクローナル抗体、及びそのタグ抗体としての利用2011
- Inventor(s)
  浦野健、辰巳香澄
- Industrial Property Rights Holder
  島根大学
- Industrial Property Number
  2011-055953
- Filing Date
  2011-03-14
- Data Source
  KAKENHI-PROJECT-21390081
[Patent] オーロラAタンパク質の活性調節剤及びその利用2005
- Inventor(s)
  浦野健, 古川鋼一
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Number
  2005-336775
- Filing Date
  2005-11-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590222
[Patent] オーロラAタンパク質の活性調節剤及びその利用2005
- Inventor(s)
  浦野健, 古川鋼一
- Industrial Property Rights Holder
  名古屋大学
- Industrial Property Number
  2005-336775
- Filing Date
  2005-11-22
- Data Source
  KAKENHI-PROJECT-16590222
[Presentation] ヒト活性型IL-18を高感度に検出する新規ELISAの開発とその応用2023
- Author(s)
  加美野宏樹、成相裕子、前田啓子、川嶋啓揮、浦野健
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K08438
[Presentation] A chimeric chemical model revealed asymmetric DNA pattern in transcribed nucleosomes2022
- Author(s)
  Kato H, Shimizu M and Urano T
- Organizer
  The 30th Hot Spring Harbor International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08438
[Presentation] ヒト膵がん細胞株MIA PaCa-2は栄養飢餓によりインターロイキン-18活性化を伴うパイロトーシスを誘導し、この現象は抗がん剤5-フルオロウラシルによって増強される2022
- Author(s)
  加美野宏樹、田島義証、浦野健
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07635
[Presentation] 活性化型マウスIL-18のネオエピトープに対する機能阻害モノクローナル抗体の作製とその評価方法の開発2022
- Author(s)
  成相裕子, 内田有紀, 尾林栄治, 田島義証, 古賀智裕, 川上純, 浦野健, 加美野宏樹
- Organizer
  第95回日本生化学会
- Data Source
  KAKENHI-PROJECT-21K08753
[Presentation] 活性化型マウスIL-18のネオエピトープに対する機能阻害モノクローナル抗体の作製とその評価方法の開発2022
- Author(s)
  成相裕子、内田有紀、尾林栄治、田島義証、古賀智裕、川上純、浦野健、加美野宏樹
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07635
[Presentation] A chimeric chemical model revealed asymmetric DNA pattern in transcribed nucleosomes2022
- Author(s)
  Kato H, Shimizu M, Urano T
- Organizer
  The 30th Hot Spring Harbor International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05556
[Presentation] 活性化型マウスIL-18のネオエピトープに対する機能阻害モノクローナル抗体の作製とその評価方法の開発2022
- Author(s)
  成相裕子, 内田有紀, 尾林栄治, 田島義証, 古賀智裕, 川上純, 浦野健, 加美野宏樹
- Organizer
  第95回日本生化学会
- Data Source
  KAKENHI-PROJECT-21K08438
[Presentation] ヒト膵がん細胞株MIA PaCa-2は栄養飢餓によりインターロイキン-18活性化を伴うパイロトーシスを誘導し、この現象は抗がん剤5-フルオロウラシルによって増強される2022
- Author(s)
  加美野宏樹、田島義証、浦野健
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K08753
[Presentation] 元外科医の基礎研究者がモノクローナル抗体作製の趣味が高じて、ベンチャーを作ってしまいました2022
- Author(s)
  浦野健
- Organizer
  第95回日本生化学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K08438
[Presentation] Development of Biopharmaceuticals using monoclonal antibodies2022
- Author(s)
  Urano T
- Organizer
  2nd Nagoya University - Chittagong University Joint Biochemistry Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08438
[Presentation] ヒト膵がん細胞株MIA PaCa-2は栄養飢餓によりインターロイキン-18活性化を伴うパイロトーシスを誘導し、この現象は抗がん剤5-フルオロウラシルによって増強される2022
- Author(s)
  加美野宏樹、田島義証、浦野健
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K08438
[Presentation] フルオロウラシル処理は低栄養培養下での膵がん細胞におけるIL-18活性化を増強する2021
- Author(s)
  加美野宏樹、内田有紀、田島義証、浦野健
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08438
[Presentation] フルオロウラシル処理は低栄養培養下での膵がん細胞におけるIL-18活性化を増強する2021
- Author(s)
  加美野宏樹、内田有紀、田島義証、浦野健
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07635
[Presentation] ケミカルハイブリッドモデルによるヌクレオソーム配置予測2021
- Author(s)
  加藤太陽、清水光弘、浦野健
- Organizer
  第93回日本遺伝学会大会
- Data Source
  KAKENHI-PROJECT-18K05556
[Presentation] ケミカルマップに基づくヌクレオソームDNAの相性予測2021
- Author(s)
  加藤太陽、清水光弘、浦野健
- Organizer
  第１４回エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-18K05556
[Presentation] 塩基構成から眺めるクロマチン2019
- Author(s)
  加藤太陽、浦野健
- Organizer
  日本遺伝学会第91回大会
- Data Source
  KAKENHI-PROJECT-18K05556
[Presentation] 成人スチル病患者血清中における活性型炎症性サイトカインIL-18の可視化を可能とした新規モノクローナル抗体の作製2019
- Author(s)
  浦野健、成相裕子、尾林栄治、加美野宏樹、右田清志、川上純
- Organizer
  第40回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-17K08983
[Presentation] （教育講演）モノクローナル抗体を用いた炎症性疾患に対するバイオ医薬品開発2019
- Author(s)
  浦野健
- Organizer
  第40回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-17K08983
[Presentation] 患者血清中における活性型炎症性サイトカインIL-18の可視化を可能とした新規モノクローナル抗体の作製2019
- Author(s)
  浦野健
- Organizer
  第５９回日本リンパ網内系学会総会
- Data Source
  KAKENHI-PROJECT-17K08983
[Presentation] Training a dHMM with a chemical map improved accuracy of nucleosome positioning prediction in yeasts2018
- Author(s)
  Kato H and Urano T
- Organizer
  Cold Spring Harbor Laboratory Meeting: Epigenetics & Chromatin
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05556
[Presentation] Preliminary study on the efficacy of conversion surgery following intensive chemotherapy for initially unresectable pancreatic cancer．2017
- Author(s)
  Kishi Takashi, Kawabata Yasunari, Nishi Takeshi, Hayashi Hikota, Tajima Yoshitsugu
- Organizer
  International association of pancreatology/Latin America pancreatic study group Joint Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10595
[Presentation] Assessment of predictive accuracy of postoperative compolication in pancreatic surgery: POSSUM vs E-PASS．2017
- Author(s)
  Hayashi Hikota, Kawabata Yasunari, Nishi Takeshi, Kishi Takashi, Tajima Yoshitsugu
- Organizer
  International association of pancreatology/Latin America pancreatic study group Joint Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10595
[Presentation] Efficacy of adjuvant chemoratiation therapy on survival in patients with curative resected pancreatic cancer.2017
- Author(s)
  Kawabata Yasunari, Hayashi Hikota, Nishi Takeshi, Kishi Takashi, Tajima Yoshitsugu.
- Organizer
  International association of pancreatology/Latin America pancreatic study group Joint Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10595
[Presentation] Biological and spatial regulation of transcriptional regulatory protein NAC-12012
- Author(s)
  Urano T.
- Organizer
  Tufts University
- Place of Presentation
  Boston, USA(招待講演)
- Year and Date
  2012-03-13
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] Biological and spatial regulation of transcriptional regulatory protein NAC-12012
- Author(s)
  Urano T
- Organizer
  Tufts University
- Place of Presentation
  Boston, USA
- Year and Date
  2012-03-13
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] 転写制御因子NAC1の細胞内動態と機能解析2010
- Author(s)
  浦野健
- Organizer
  第9回核ダイナミクス研究会
- Place of Presentation
  ラフォーレ修善寺(静岡)
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] 転写制御因子NAC1の細胞内動態と機能解析2010
- Author(s)
  浦野健
- Organizer
  第9回核ダイナミクス研究会
- Place of Presentation
  静岡
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] SUMO化による分裂期キナーゼAuroraの制御2010
- Author(s)
  浦野健
- Organizer
  第8回SUMO研究会
- Place of Presentation
  筑波
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] The spatial regulation of a transcriptional regulator NAC-1.2010
- Author(s)
  Urano T
- Organizer
  The 1st International Worksh op on Structural Epigenomics
- Place of Presentation
  Riken Yokohama Institute Koryuto Hall(Y okohama)
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] Biological and domain analysis of transcriptional regulatory prote in NAC-12010
- Author(s)
  Urano T.
- Organizer
  The 6^<th> International Forum on Oxidative Stress and Aging
- Place of Presentation
  Nagoya Congress Center(Nagoya)
- Year and Date
  2010-09-07
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] Biological and domain analysis of transcriptional regulatory protein NAC-1.2010
- Author(s)
  Urano T.
- Organizer
  The 6^<th> International Forum on Oxidative Stress and Aging
- Place of Presentation
  Nagoya(招待講演)
- Year and Date
  2010-09-07
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] The spatial regulation of a transcriptional regulator NAC-1.2010
- Author(s)
  Urano T.
- Organizer
  The 1st International Workshop on Structural Epigenomics
- Place of Presentation
  Yokohama(招待講演)
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] SUMO化による分裂期キナーゼAuroraの制御2010
- Author(s)
  浦野健
- Organizer
  第8回SUMO研究会
- Place of Presentation
  筑波大学(筑波)
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-21390081
[Presentation] Calcium/Calmodulin Binds to and Inhibits Aurora-A Kinase Activity at Anaphase.2008
- Author(s)
  Takeshi Urano
- Organizer
  48^th ASCB
- Place of Presentation
  San Francisco (USA)
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-18390083
[Presentation] 細胞周期を制御する分裂期キナーゼAurora2007
- Author(s)
  浦野健
- Organizer
  第16回日本アポトーシス研究会
- Place of Presentation
  千葉東邦大学
- Year and Date
  2007-08-04
- Data Source
  KAKENHI-PROJECT-17013043
[Presentation] 細胞周期を制御する分裂期キナーゼAurora2007
- Author(s)
  浦野健
- Organizer
  第16回日本アポトーシス研究会
- Place of Presentation
  千葉
- Year and Date
  2007-08-04
- Data Source
  KAKENHI-PROJECT-18390083
[Presentation] 細胞周期を制御する分裂期キナーゼAurora2007
- Author(s)
  浦野健
- Organizer
  第16回日本アポトーシス研究会(招待講演)
- Place of Presentation
  千葉
- Year and Date
  2007-08-04
- Data Source
  KAKENHI-PROJECT-18390083
[Presentation] Calcium/Calmodulin Binds to and Inhibits Aurora-A Kinase Activity at Anaphase2000
- Author(s)
  Reiko Ban and Takeshi Urano
- Organizer
  48^<th> ASCB
- Place of Presentation
  San Francisco (USA)
- Data Source
  KAKENHI-PROJECT-18390083

1. FURUKAWA Koichi (80211530)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. Migita Kiyoshi (60264214)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. Koga Tomohiro (90537284)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 川上純 (90325639)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. Tajima Yoshitsugu (20264228)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
6. FURUKAWA Keiko (50260732)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. Obayashi Eiji (50321740)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. KAMINO Hiroki (00625692)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
9. 杉浦智子 (60647402)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
10. SAKASHITA Gyosuk (00397457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. NISHI Takeshi (80538893)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
12. 吉浦孝一郎 (00304931)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 田中義正 (90280700)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. ISHIKAWA Fuyuki (30184493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. NABETANI Akira (40334495)

# of Collaborated Projects: 1 results

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16. BAN Reiko (40509105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. KONDO Seiji (10432634)

# of Collaborated Projects: 1 results

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18. SEKINE Joji (20236095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Park Sam-Yong (20291932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. Sugiyama Kanako (20623226)

# of Collaborated Projects: 1 results

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21. TAJIMA Orie (10362237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. Kato Hiroaki (40548418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
23. 内田有紀 (60868719)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. ヌグエ・トンミャ・ミャッ (90772583)

# of Collaborated Projects: 1 results

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25. 森田公一 (40182240)

# of Collaborated Projects: 1 results

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26. 野津雅和 (50709144)

# of Collaborated Projects: 1 results

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27. 増本純也 (20334914)

# of Collaborated Projects: 1 results

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28. 小迫英尊 (10291171)

# of Collaborated Projects: 1 results

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29. 竹田浩之 (40609393)

# of Collaborated Projects: 1 results

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30. 岸田大 (50467180)

# of Collaborated Projects: 1 results

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31. 山中聡士 (50853884)

# of Collaborated Projects: 1 results

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32. NAGATA Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 前田啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 粕壁隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 雲財悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 堺弘道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 清水光弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Urano Takeshi 浦野 健

URANO Takeshi 浦野 健

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Basic research on antibody therapy against inflammatory cytokine IL-18 for refractory inflammatory diseasesPrincipal Investigator

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Urano Takeshi 浦野健

URANO Takeshi 浦野健