Ogino Kazuhide 荻野和秀

… Alternative Names

OGINO Kazuhide 荻野和秀

荻野和秀オギノカズヒデ

KAZUHIDE Ogino 荻野和秀

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Researcher Number	70294311
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2019: 鳥取大学, 医学(系)研究科(研究院), 特任教授 2018: 鳥取大学, 医学部, プロジェクト研究員 2013 – 2017: 鳥取大学, 医学部附属病院, 准教授 2008 – 2010: Tottori University, 医学部附属病院, 准教授 2005 – 2006: 鳥取大学, 医学部附属病院, 助教授 1998 – 2002: 鳥取大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Cardiovascular medicine / Circulatory organs internal medicine / Circulatory organs internal medicine / Emergency medicine Except Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator 拡張不全 / cAMP / 心不全 / インスリン抵抗性 / 薬理学 / 循環器・高血圧 / 左室拡張不全 / 酸化ストレス / キサンチンオキシダーゼ / 尿酸 … More / Signal transduction / Protein kinase / Fragment / Pacemaker current / Vasodilatory effect / Positive chronotronpic effect / Parathyroid hormone / ペースメーカー電流(If) / 灌流心 / 陽性変事作用 / 細胞内情報伝達系 / プロテインキナーゼ / フラグメント / ペースメーカー電流 / 血管拡張作用 / 陽性変時作用 / 副甲状腺ホルモン / 高血圧 / アルドステロン / インスリン抗性 / 糖代謝異常 / IMP / 肺障害 / AMP deaminase / 虚血再潅流 / イノシン / AMPデアミナーゼ / 虚血再潅流障害 … More Except Principal Investigator AMP deaminase / Na^+channel blocker / degradation / proteasome / ubiquitin / ion channel / 細胞内輸送 / Kv1.5 / 再生 / イオンチャンネル / ユビキチン化 / Na^+ channel阻害剤 / プロテアソーム / イオンチャネル / human heat / myosin heary chain / Ischemic preconditioning / ミオシン重鎖 / AMP deaminase family / AMP deaminase、 / ヒト心臓 / myosin heavy chain / Ischemic peconditioning Less

Effects of a xanthine oxidase inhibitor on left ventricular diastolic dysfunctionPrincipal Investigator
- Principal Investigator
  
  OGINO Kazuhide
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
New treatment for left ventricular diastolic failurePrincipal Investigator
- Principal Investigator
  
  Ogino Kazuhide
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Tottori University
New therapy for diastolic heart failure from the standpoint of insulin resistancePrincipal Investigator
- Principal Investigator
  
  OGINO Kazuhide
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University
reperfusion injuryによる心臓・肺障害の機序の解明と治療法の開発Principal Investigator
- Principal Investigator
  
  荻野和秀
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Emergency medicine
- Research Institution
  Tottori University
Mechanisms on the degradation of ion channel proteins and their modification by antiarrythmic agents
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Department of Cardiovascular Medicine, Tottori University Faculty of Medicine
Novel mechanism on the ischemic preconditioning : Role of AMP deaminase family for adenosine production
- Principal Investigator
  
  HISATOME Ichiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University
The hamodynamic effects of PTH and PTHrP in cardiovascular systemPrincipal Investigator
- Principal Investigator
  
  KAZUHIDE Ogino
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tottori University

All 2020 2019 2018 2017 2016 2015 2014 2011 2010 2009 2008 Other

All Journal Article Presentation Other

[Journal Article] Pretreatment with an angiotensin II receptor blocker abolished ameliorating actions of adipose-derived stem cell sheets on cardiac dysfunction and remodeling after myocardial infarction2018
- Author(s)
  Yamamoto Kenshiro、Kurata Yasutaka、Inoue Yumiko、Adachi Maya、Tsuneto Motokazu、Miake Junichiro、Ogino Kazuhide、Ninomiya Haruaki、Yoshida Akio、Shirayoshi Yasuaki、Suyama Yoshiko、Yagi Shunjiro、Nishimura Motonobu、Yamamoto Kazuhiro、Hisatome Ichiro
- Journal Title
  
  Regenerative Therapy
  
  Volume: 9 Pages: 79-88
- DOI
  10.1016/j.reth.2018.08.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09436, KAKENHI-PROJECT-17K09580, KAKENHI-PROJECT-17K11539, KAKENHI-PROJECT-16K11367
[Journal Article] Protective Effects of Topiroxostat on an Ischemia-Reperfusion Model of Rat Hearts2018
- Author(s)
  Tanno S. et al.
- Journal Title
  
  Circ J
  
  Volume: 82 Issue: 4 Pages: 1101-1111
- DOI
  10.1253/circj.CJ-17-1049
- NAID
  130006528600
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08277, KAKENHI-PROJECT-16K09436, KAKENHI-PROJECT-17K08761
[Journal Article] Prevalence and complications of hypouricemia in a general population: A large-scale cross-sectional study in Japan2017
- Author(s)
  Kuwabara M, Niwa K, Ohtahara A, Hamada T, Miyazaki S, Mizuta E, Ogino K, Hisatome I.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 4 Pages: e0176055-e0176055
- DOI
  10.1371/journal.pone.0176055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09436
[Journal Article] Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.2016
- Author(s)
  Mishima M, Anzai N, et al.
- Journal Title
  
  Drug Res
  
  Volume: 66 Issue: 05 Pages: 270-274
- DOI
  10.1055/s-0035-1569405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670600, KAKENHI-PROJECT-25461057, KAKENHI-PROJECT-26461258
[Journal Article] Effect of Antihypertensive Drugs on Uric Acid Metabolism in Patients with Hypertension: Cross-Sectional Cohort Study.2016
- Author(s)
  Ueno S, Hamada T, Taniguchi S, Ohtani N, Miyazaki S, Mizuta E, Ohtahara A, Ogino K, Yoshida A, Kuwabara M, Yoshida K, Ninomiya H, Kotake H, Taufiq F, Yamamoto K, Hisatome I
- Journal Title
  
  Drug Res (Stuttg)
  
  Volume: 66 Pages: 628-632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461057
[Journal Article] <b>Adipose stem cell sheets improved cardiac function in the rat myocardial infarction, but did not alter cardiac contractile responses to β-adrenergic stim</b><b>ulation </b>2015
- Author(s)
  Otsuki Y, Nakamura Y, Harada S, Yamamoto Y, Ogino K, Morikawa K, Ninomiya H, Miyagawa S, Sawa Y, Hisatome I, Nishimura M.
- Journal Title
  
  Biomed. Res.
  
  Volume: 36 Issue: 1 Pages: 11-19
- DOI
  10.2220/biomedres.36.11
- NAID
  130004903877
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25893134, KAKENHI-PROJECT-25461057
[Journal Article] Depletion of Uric Acid Due to SLC22A12 (URAT1) Loss-of-Function Mutation Causes Endothelial Dysfunction in Hypouricemia2015
- Author(s)
  Sugihara S, Hisatome I, Kuwabara M, Niwa K, Maharani N, Kato M, Ogino K, Hamada T, Ninomiya H, Higashi Y, Ichida K, Yamamoto K
- Journal Title
  
  Circ J
  
  Volume: 79 Issue: 5 Pages: 1125-1132
- DOI
  10.1253/circj.CJ-14-1267
- NAID
  130005066259
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461057, KAKENHI-PROJECT-25461058, KAKENHI-PROJECT-25670762
[Journal Article] Spironolactone, not furosemide, improved insulin resistance in patients with chronic heart failure2014
- Author(s)
  Ogino K, Kinugasa Y, Kato M, Yamamoto K, Hisatome I, Anker SD, Doehner W
- Journal Title
  
  Int J Cardiol
  
  Volume: 171 Issue: 3 Pages: 398-403
- DOI
  10.1016/j.ijcard.2013.12.039
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461057
[Journal Article] Addition of losartan to angiotensin-converting enzyme inhibitors improves insulin resistance in patients with chronic heart failure treated without ss-blockers.2011
- Author(s)
  荻野和秀
- Journal Title
  
  Circulation Journal
  
  Volume: 74 Pages: 2346-2352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590826
[Journal Article] Uric acid-lowering treatment with benzbromarone in patients with heart failure : a doubleblind placebo-controlled crossover preliminary study.2010
- Author(s)
  Ogino K, Kato M, Furuse Y, Kinugasa Y, Ishida K, Osaki S, Kinugawa T, Igawa O, Hisatome I, Shigemasa C, Anker SD, Doehner W.
- Journal Title
  
  Circ Heart Fail. Jan;3:
  
  Pages: 73-81
- Data Source
  KAKENHI-PROJECT-20590826
[Journal Article] Addition of losartan to angiotensin- converting enzyme inhibitors improves insulin resistance in patients with chronic heart failure treated without β-blockers.2010
- Author(s)
  Ogino K, Kato M, Furuse Y, Kinugasa Y, Kaetsu Y, Mizuta E, Sugihara S, Ishida K, Yanagihara K, Hisatome I, Shigemasa C.
- Journal Title
  
  Circ J. 74
  
  Pages: 2346-2352
- NAID
  10026972758
- Data Source
  KAKENHI-PROJECT-20590826
[Journal Article] Uric acid-lowering treatment with benzbromarone in patients with heart failure : A double blind placebo-controlled crossover preliminary study2010
- Author(s)
  荻野和秀
- Journal Title
  
  Circulation Heart Failure 3
  
  Pages: 73-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] フェブキソスタットは酸化ストレス軽減を介して左室拡張機能障害を改善する2020
- Author(s)
  荻野和秀
- Organizer
  第53回日本痛風・核酸代謝学会
- Data Source
  KAKENHI-PROJECT-16K09436
[Presentation] Uric Acid-Lowering Treatment by a Xanthine Oxidase Inhibitor Improved the Diastolic Function in Patients with Hyperuricemia2019
- Author(s)
  Kazuhide Ogino
- Organizer
  HFSA 2019 Annual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09436
[Presentation] ラット慢性虚血性心不全に対するトピロキソスタットとイルベサルタンの効果2019
- Author(s)
  荻野和秀、丹野翔伍、杉原志伸、浜田紀宏、太田原顕、桑原政成、山本康孝、山本一博、久留一郎
- Organizer
  第52回日本痛風・核酸代謝学会
- Data Source
  KAKENHI-PROJECT-16K09436
[Presentation] Losartan/hydrochlorothiazide combination therapy improved left ventricular diastolic dysfunction in patients with hypertension in comparison with a high-dose therapy of losartan2016
- Author(s)
  Ogino K, Kinugasa Y, Kato M, Hisatome I, Yamamoto K
- Organizer
  American Society of Hypertension 2016
- Place of Presentation
  Hilton Hotel, New York, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461057
[Presentation] Uric AcidLowering Treatment in Patients with Left Ventricular Diastolic2015
- Author(s)
  Ogino K
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪国際会議場（大阪府，北区）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-25461057
[Presentation] The effects of losartan on insulin resistance in patients with chronic heart failure treated with ACE inhibitors.2011
- Author(s)
  荻野和秀、水田栄之助、杉原志伸、柳原清孝、石田勝則、衣笠良治、古瀬祥之、加藤雅彦、浜田紀宏、重政千秋、山本康孝、久留一郎
- Organizer
  プリン・ピリミジン代謝国際シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] ACE阻害薬治療中の心不全におけるロサルタン追加投与のインスリン抵抗性に及ぼす影響2011
- Author(s)
  荻野和秀、水田栄之助、杉原志伸、柳原清孝、石田勝則、衣笠良治、古瀬祥之、加藤雅彦、浜田紀宏、重政千秋、山本康孝、久留一郎
- Organizer
  第44回日本痛風核酸代謝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] ACE阻害薬治療中の心不全におけるロサルタン追加投与のインスリン抵抗性に及ぼす影響2011
- Author(s)
  荻野和秀
- Organizer
  第44回日本痛風・核酸代謝学会学術集会
- Place of Presentation
  東京、京王プラザホテル
- Year and Date
  2011-02-17
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] The effects of losartan on insulin resistance in patients with chronic heart failure treated with ACE inhibitors2011
- Author(s)
  荻野和秀
- Organizer
  14^<th> International Symposium on Purine and Pyrimidine Metabolism in Man (PP11)
- Place of Presentation
  東京、京王プラザホテル
- Year and Date
  2011-02-19
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Matrix metalloproteinase were produced in failing hearts and were decreased with spironolactone in patients with chronic heart failure2009
- Author(s)
  荻野和秀
- Organizer
  ヨーロッパ心不全学会
- Place of Presentation
  フランス・ニース
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Spironolactone, not furosemide, improved insulin resistance in patients with chronic heart failure.2009
- Author(s)
  荻野和秀、加藤雅彦、久留一郎、重政千秋
- Organizer
  日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Spironolactone, not Furosemide, Improved Insulin Resistance in Patients with Chronic Heart Failure2009
- Author(s)
  荻野和秀
- Organizer
  日本循環器学会
- Place of Presentation
  大阪
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Matrix metalloproteinase were produced in failing hearts and were decreased with spironolactone in patients with chronic heart failure.2009
- Author(s)
  荻野和秀、加藤雅彦、久留一郎、重政千秋
- Organizer
  ヨーロッパ心不全学会
- Place of Presentation
  ニース
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Matrix Metalloproteinases Were Produced in Failing Hearts and Were Decreased With Spironolactone in Patients With Chronic Heart Failure2008
- Author(s)
  荻野和秀
- Organizer
  アメリカ心不全学会
- Place of Presentation
  カナダ・トロント
- Year and Date
  2008-09-22
- Data Source
  KAKENHI-PROJECT-20590826
[Presentation] Matrix metalloproteinases were produced in failing hearts and were decreased with spironolactone in patients with chronic heart failure.2008
- Author(s)
  荻野和秀、加藤雅彦、久留一郎、重政千秋
- Organizer
  アメリカ心不全学会
- Place of Presentation
  トロント
- Data Source
  KAKENHI-PROJECT-20590826
[]

1. HISATOME Ichiro (60211504)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
2. MORISAKI Takayuki (30174410)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TANIGUCHI Shin-ichi (30304207)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TANAKA Yasonori (60294310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IGAWA Osamu (80252857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SASAKI Norihito (70346336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 星川淑子 (10181489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OHTAHARA Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 安西尚彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogino Kazuhide 荻野 和秀

OGINO Kazuhide 荻野 和秀

荻野 和秀 オギノ カズヒデ

KAZUHIDE Ogino 荻野 和秀

Research Projects

Research Products

Co-Researchers

Effects of a xanthine oxidase inhibitor on left ventricular diastolic dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New treatment for left ventricular diastolic failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New therapy for diastolic heart failure from the standpoint of insulin resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

reperfusion injuryによる心臓・肺障害の機序の解明と治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms on the degradation of ion channel proteins and their modification by antiarrythmic agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel mechanism on the ischemic preconditioning : Role of AMP deaminase family for adenosine production

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The hamodynamic effects of PTH and PTHrP in cardiovascular systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Pretreatment with an angiotensin II receptor blocker abolished ameliorating actions of adipose-derived stem cell sheets on cardiac dysfunction and remodeling after myocardial infarction2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective Effects of Topiroxostat on an Ischemia-Reperfusion Model of Rat Hearts2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Prevalence and complications of hypouricemia in a general population: A large-scale cross-sectional study in Japan2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Antihypertensive Drugs on Uric Acid Metabolism in Patients with Hypertension: Cross-Sectional Cohort Study.2016

Author(s)

Journal Title

Data Source

[Journal Article] <b>Adipose stem cell sheets improved cardiac function in the rat myocardial infarction, but did not alter cardiac contractile responses to β-adrenergic stim</b><b>ulation </b>2015

Author(s)

Journal Title

DOI

Ogino Kazuhide 荻野和秀

OGINO Kazuhide 荻野和秀

荻野和秀オギノカズヒデ

KAZUHIDE Ogino 荻野和秀