Hoshino Masaru 星野大

… Alternative Names

星野大ホシノマサル

MASARU Hoshino 星野大

HOSHINO Masaru 星野大

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Researcher Number	70304053
Other IDs
External Links
Affiliation (Current)	2025: 京都大学, 薬学研究科, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 京都大学, 薬学研究科, 准教授 2016 – 2020: 京都大学, 薬学研究科, 准教授 2015: 京都大学, 大学院薬学研究科, 准教授 2011 – 2015: 京都大学, 薬学研究科(研究院), 准教授 2013: 京都大学, 大学院薬学研究科, 准教授 … More 2007 – 2009: Kyoto University, 薬学研究科, 准教授 2005: 京都大学, 薬学研究科, 助教授 2004: 阪大, たんぱく質研究所, 助手 2002 – 2003: 大阪大学, たんぱく質研究所, 助手 2001 – 2003: 大阪大学, 蛋白質研究所, 助手 1999 – 2000: 大阪大学, たんぱく質研究所, 助手 Less
Review Section/Research Field	Principal Investigator Biophysics / Basic Section 43020:Structural biochemistry-related / Basic Section 43040:Biophysics-related / Structural biochemistry / Biological Sciences / Biophysics Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields / Biophysics / Physical pharmacy / Pharmaceutical Sciences and related fields / Biological Sciences
Keywords	Principal Investigator NMR / ＮＭＲ / GroE / 分子シャペロン / 分子間相互作用 / グルタミンリッチドメイン / 転写因子 / 天然変性蛋白質 / 可溶性オリゴマー / アミロイドβ … More / アミロイド線維 / 重水素交換 / 核磁気共鳴 / 立体構造変化 / タンパク質間相互作用 / 分子認識 / 天然変性タンパク質 / 高分解能NMR / 逆ミセル封入法 / 逆ミセル / 核磁気共鳴分光法 / TAF4 / Sp1 / 相互作用解析 / 表面プラズモン共鳴 / 相互作用 / タンパク質 / 構造解析 / アミロイド / シャペロニン / フォールディング / CroE / 構造生物学 / 会合・凝集 / ダイナミクス / β2ミクログロブリン / アミロイド病 / 折れたたみ反応 … More Except Principal Investigator 膜タンパク質 / 可溶化剤 / 蛋白質 / 高分解能NMR / β2ミクログロブリン / 膜タンパク質可溶化 / ＮＭＲ / Amyloid β-peptide / β2-microglobulin / D exchange / H / Fluorescence microscopy / Dialysis-related amyloidosis / Stability of proteins / Protein folding / Amyloid fibril / 一分子観察 / NMR / フォールディング / アミロイド病 / アミロイドβペプチド / 重水素交換 / 水素 / 蛍光顕微鏡 / 透析アミロイドーシス / 蛋白質の構造安定性 / 蛋白質のフォールディング / アミロイド線維 / Amyloid Fibril / Single Molecule Analysis / Fluorescence / β2-Microglobulin / β-Lactoglobulin / Heteronuclear NMR / Protein Folding / Protein / 変性 / メタノール資化酵母 / 安定同位体標識蛋白質 / βラクトグロブリン / α-β転移 / 核磁気共鳴 / フォールディング反応 / 無細胞合成 / 脂質ナノディスク / 膜蛋白質 / 線維構造 / 凝集阻害 / ガングリオシド / 脂質ラフト / アミロイドβ蛋白 / アルツハイマー病 Less

新規リン脂質誘導体可溶化剤を用いた革新的膜タンパク質研究プラットホームの構築
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
Mechanism of molecular recognition between intrinsically disordered regions.Principal Investigator
- Principal Investigator
  
  星野大
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kyoto University
High resolution NMR structure determination of membrane proteins using novel phospholipid analogs
- Principal Investigator
  
  Matsuzaki Katsumi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
NMR analysis of amyloid-beta soluble oligomer encapsulated in reverse micellePrincipal Investigator
- Principal Investigator
  
  Hoshino Masaru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
Novel Phospholipid Analogs for NMR Structural Determination of Membrane Proteins
- Principal Investigator
  
  Matsuzaki Katsumi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Kyoto University
Molecular mechanism of interaction between transcriptional factors Sp1 and TAF4.Principal Investigator
- Principal Investigator
  
  Hoshino Masaru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University
Development of phospholipid analogs for stable solubilization of membrane proteins and application for high resolution NMR analysis
- Principal Investigator
  
  Matsuzaki Katsumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
グルタミンリッチ型転写活性化ドメインの相互作用解析Principal Investigator
- Principal Investigator
  
  星野大
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Development of novel nano discs for structural analysis of membrane proteins
- Principal Investigator
  
  MATSUZAKI Katsumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
NMR analysis of amyloid beta-oligomer by using molecular chaperone encapsulation system.Principal Investigator
- Principal Investigator
  
  MASARU Hoshino
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Kyoto University
Novel chaperonin-encapsulation system for aggregation-prone proteins.Principal Investigator
- Principal Investigator
  
  HOSHINO Masaru
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  Kyoto University
GM1結合型アミロイドβ蛋白の構造解析
- Principal Investigator
  
  MATSUZAKI Katsumi
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
高分解能NMRによるアミロイド線維の構造解析Principal Investigator
- Principal Investigator
  
  星野大
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
高分解能NMRによるGroE-基質複合体の直接観測Principal Investigator
- Principal Investigator
  
  星野大
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
Understanding the amyloid fibril formation of β2-microglobulin on the basis of protein conformation
- Principal Investigator
  
  GOTO Yuji
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
Role of α-β transition in the folding of proteins
- Principal Investigator
  
  GOTO Yuji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Biophysics
- Research Institution
  Osaka University

[Journal Article] Insights into the dual nature of alphaB crystallin chaperone activity from the p.P39L mutant at the N-terminal region.2024
- Author(s)
  A. Barati, L.R. Somee, M.B. Shahsavani, A. Ghasemi, M. Hoshino, J. Hong, A.A. Saboury, A.A. Moosavi-Movahedi, G. Agnetti & R. Yousefi
- Journal Title
  
  Sci. Rep.
  
  Volume: 14 Issue: 1 Pages: 7353-7353
- DOI
  10.1038/s41598-024-57651-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06101
[Journal Article] Unraveling the impact of the p.R107L mutation on the structure and function of human aB-Crystallin: Implications for cataract formation.2024
- Author(s)
  F. Nasiri, P. Ebrahimi, M.B. Shahsavani, A. Barati, I. Zarei, J. Hong, M. Hoshino, A.A. Moosavi-Movahedi & R. Yousefi
- Journal Title
  
  Biochimie
  
  Volume: 222 Pages: 151-168
- DOI
  10.1016/j.biochi.2024.03.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06101
[Journal Article] Unveiling the structural and functional consequences of the p.D109G pathogenic mutation in human alphaB-Crystallin responsible for restrictive cardiomyopathy and skeletal myopathy.2024
- Author(s)
  M.H. Jafari, M.B. Shahsavani, M. Hoshino, J. Hong, A.A. Saboury, A.A. Moosavi-Movahedi & R. Yousefi
- Journal Title
  
  Int. J. Biol. Macromol.
  
  Volume: 254 Pages: 127933-127933
- DOI
  10.1016/j.ijbiomac.2023.127933
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06101
[Journal Article] Charge manipulation of the human insulin B chain C-terminal to shed light on the complex mechanism of insulin fibrillation.2024
- Author(s)
  M.B. Shahsavani, M. Hoshino, A. Kumar & R. Yousefi
- Journal Title
  
  10.1016/j.bbagen.2024.130578
  
  Volume: 1868 Issue: 4 Pages: 130578-130578
- DOI
  10.1016/j.bbagen.2024.130578
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06101
[Journal Article] Understanding the structural and functional changes and biochemical pathomechanism of the cardiomyopathy-associated p.R123W mutation in human alphaB-crystallin.2024
- Author(s)
  L.R. Somee, A. Barati, M.B. Shahsavani, M. Hoshino, J. Hong, A. Kumar, A.A. Moosavi-Movahedi, M. Amanlou & R. Yousefi
- Journal Title
  
  BBA General Subjects
  
  Volume: 1868 Issue: 4 Pages: 130579-130579
- DOI
  10.1016/j.bbagen.2024.130579
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06101
[Journal Article] Optimizing expression, purification, structural and functional assessments of a novel dimeric incretin (GLP-1cpGLP-1).2023
- Author(s)
  R.M. Albaghlany, M.B. Shahsavani, M. Hoshino, A.A. Moosavi-Movahedi, Y. Ghasemi & R. Yousefi
- Journal Title
  
  Biochimie
  
  Volume: - Pages: 133-146
- DOI
  10.1016/j.biochi.2023.10.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06101
[Journal Article] A novel mode of interaction between intrinsically disordered proteins2020
- Author(s)
  E. Hibino & M. Hoshino
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 17 Issue: 0 Pages: 86-93
- DOI
  10.2142/biophysico.BSJ-2020012
- NAID
  130007889459
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06151
[Journal Article] Letter to the Editor: A still unresolved mystery in the interaction between intrinsically disordered proteins: How do they recognize multiple target proteins? A commentary on “No folding upon binding of intrinsically disordered proteins: Still interesting but not unique and novel. by Sigalov, A. B., Biophysics and Physicobiology 17, 156–158 (2020). DOI: 10.2142/biophysico.BSJ-2020025”2020
- Author(s)
  M. Hoshino
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 17 Issue: 0 Pages: 159-160
- DOI
  10.2142/biophysico.BSJ-2020028
- NAID
  130007958012
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06151
[Journal Article] Structural characterization of the N-terminal kinase-interacting domain of an Hsp90-cochaperone Cdc37 by CD and solution NMR spectroscopy.2019
- Author(s)
  Ihama, F., Yamamoto, M., Kojima, C., Fujiwara, T., Matsuzaki, K., Miyata, Y., Hoshino, M.
- Journal Title
  
  Biochim. Biophys. Acta-Proteins Proteom.
  
  Volume: 1867 Issue: 9 Pages: 813-820
- DOI
  10.1016/j.bbapap.2019.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06131, KAKENHI-PROJECT-18K06151, KAKENHI-PUBLICLY-19H04856, KAKENHI-PROJECT-17H03641
[Journal Article] Novel Interaction Mechanism between the Intrinsically Disordered Proteins2019
- Author(s)
  日比野絵美, 星野大
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 59 Issue: 4 Pages: 202-204
- DOI
  10.2142/biophys.59.202
- NAID
  130007683547
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06151
[Journal Article] Toxic amyloid tape: A novel mixed antiparallel/parallel beta-sheet structure formed by amyloid beta-protein on GM1 clusters.2019
- Author(s)
  Y. Okada, K. Okubo, K. Ikeda, Y. Yano, M. Hoshino, Y. Hayashi, Y. Kiso, H. Itoh-Watanabe, A. Naito & K. Matsuzaki
- Journal Title
  
  ACS Chem. Neurosci.
  
  Volume: 10 Issue: 1 Pages: 563-572
- DOI
  10.1021/acschemneuro.8b00424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06151
[Journal Article] Not Oligomers but Amyloids are Cytotoxic in the Membrane-Mediated Amyloidogenesis of Amyloid-beta Peptides.2018
- Author(s)
  N. Itoh, E. Takada, K. Okubo, Y. Yano, M. Hoshino, A. Sasaki, M. Kinjo & K. Matsuzaki
- Journal Title
  
  ChemBioChem
  
  Volume: 19 Issue: 5 Pages: 430-433
- DOI
  10.1002/cbic.201700576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06151
[Journal Article] Use of a compact tripodaltris(bipyridine) ligand to stabilize a single metal-centered chirality: stereoselective coordination of iron(II) and ruthenium(II) on a semi-rigid hexapeptide macrocycle.2018
- Author(s)
  Y.Kobayashi, M. Hoshino, T. Kameda, K. Kobayashi, K. Akaji, S. Inuki, H. Ohno & S. Oishi
- Journal Title
  
  Inorg. Chem.
  
  Volume: 57 Issue: 9 Pages: 5475-5485
- DOI
  10.1021/acs.inorgchem.8b00416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06151
[Journal Article] Aromaticity of Phenylalanine Residues is Essential for Amyloid Formation by Alzheimer's Amyloid beta-Peptide2017
- Author(s)
  M. Genji, Y. Yano, M. Hoshino & K. Matsuzaki
- Journal Title
  
  Chem. Pharm. Bull.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26440025
[Journal Article] Fibril formation from the amyloid-beta peptide is governed by a dynamic equilibrium involving association and dissociation of the monomer.2016
- Author(s)
  M. Hoshino
- Journal Title
  
  Biophys. Rev.
  
  Volume: - Issue: 1 Pages: 1-8
- DOI
  10.1007/s12551-016-0217-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26440025
[Journal Article] Interaction between intrinsically disordered regions in transcription factors Sp1 and TAF42016
- Author(s)
  E. Hibino, R. Inoue, M. Sugiyama, J. Kuwahara, K. Matsuzaki, and M. Hoshino
- Journal Title
  
  Protein Science
  
  Volume: ２５ Issue: 11 Pages: 2006-2017
- DOI
  10.1002/pro.3013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H01306, KAKENHI-PROJECT-15H02042, KAKENHI-PROJECT-26440025, KAKENHI-PROJECT-15K18515
[Journal Article] Effects of C-terminal Truncation of Chaperonin GroEL on the Yield of In-cage Folding of the Green Fluorescent Protein.2015
- Author(s)
  S. Ishino, Y. Kawata, H. Taguchi, N. Kajimura, K. Matsuzaki & M. Hoshino
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 24 Pages: 15042-15051
- DOI
  10.1074/jbc.m114.633636
- NAID
  120005690196
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440025, KAKENHI-ORGANIZER-26116001, KAKENHI-PLANNED-26116002
[Journal Article] The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates.2015
- Author(s)
  Morimoto D,Walinda E, Fukada H, Sou YS, Kageyama S, Hoshino M, Fujii T, Tsuchiya H, Saeki Y, Arita K, Ariyoshi M, Tochio H, Iwai K, Namba K, Komatsu M, Tanaka K, Shirakawa M.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Issue: 1 Pages: 6116-6116
- DOI
  10.1038/ncomms7116
- NAID
  120005528125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-21121006, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-25000013, KAKENHI-PLANNED-25111006, KAKENHI-PUBLICLY-25112514, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-26440025, KAKENHI-PROJECT-26860224, KAKENHI-PROJECT-25253019, KAKENHI-PROJECT-26000014
[Journal Article] Evaluation of the stability of an SR398/GroES chaperonin complex2014
- Author(s)
  S. Ishino, Y. Kawata, T. Ikegami, K. Matsuzaki & M. Hoshino.
- Journal Title
  
  J. Biochemistry
  
  Volume: 155 (5) Issue: 5 Pages: 295-300
- DOI
  10.1093/jb/mvu009
- NAID
  40020056292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570192, KAKENHI-PROJECT-26440025
[Journal Article] Evaluation of the stability of an SR398/GroES chaperonin complex.2014
- Author(s)
  S. Ishino, Y. Kawata, T. Ikegami, K. Matsuzaki, M. Hoshino
- Journal Title
  
  J. Biochem.
  
  Volume: unknown
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24113708
[Journal Article] Comparison between the Aggregation of Human and Rodent Amyloid beta-Proteins in GM1 Ganglioside Clusters.2014
- Author(s)
  H. Ueno, T. Yamaguchi, S. Fukunaga, Y. Okada, Y. Yano, M. Hoshino & K. Matsuzaki
- Journal Title
  
  Biochemistry
  
  Volume: 53 (48) Issue: 48 Pages: 7523-7530
- DOI
  10.1021/bi501239q
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26440025
[Journal Article] Evaluation of the stability of an SR398/GroES chaperonin complex.2014
- Author(s)
  S. Ishino, Y. Kawata, T. Ikegami, K. Matsuzaki, M. Hoshino
- Journal Title
  
  J. Biochem.
  
  Volume: unknown
- NAID
  40020056292
- Data Source
  KAKENHI-PROJECT-23570192
[Journal Article] Interaction between soluble Abeta-(1-40) monomer and Abeta-(1-42) fibrils probed by paramagnetic relaxation enhancement.2013
- Author(s)
  T. Yamaguchi, K. Matsuzaki & M. Hoshino
- Journal Title
  
  FEBS Lett.
  
  Volume: 587 Issue: 6 Pages: 620-624
- DOI
  10.1016/j.febslet.2013.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570192, KAKENHI-PUBLICLY-24113708
[Journal Article] Structure-Activity Relationship Study of a CXC Chemokine Receptor Type 4 Antagonist, FC131, Using a Series of Alkene Dipeptide Isosteres2012
- Author(s)
  Kobayashi K., et al
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: (in press) Issue: 6 Pages: 2746-2757
- DOI
  10.1021/jm2016914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J02083, KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23570192, KAKENHI-PROJECT-23689007
[Journal Article] Interaction between isolated transcriptional activation domains of Sp1 revealed by heteronuclear magnetic resonance.2012
- Author(s)
  N. Hiramatsu, E. Hibino, K. Matsuzaki, J. Kuwahara & M. Hoshino
- Journal Title
  
  Protein Sci.
  
  Volume: 21 Issue: 10 Pages: 1481-1488
- DOI
  10.1002/pro.2137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570192, KAKENHI-PUBLICLY-24113708
[Journal Article] GM1 cluster mediates formation of toxic Abeta fibrils by providing hydrophobic environments.2012
- Author(s)
  S. Fukunaga, H. Ueno, T. Yamaguchi, Y. Yano, M. Hoshino & K. Matsuzaki
- Journal Title
  
  Biochemistry
  
  Volume: 51 Issue: 41 Pages: 8125-8131
- DOI
  10.1021/bi300839u
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570192, KAKENHI-PUBLICLY-24113708
[Journal Article] Transient formation of intermediate conformational states of amyloid-beta peptide revealed by heteronuclear magnetic resonance spectroscopy.2011
- Author(s)
  T. Yamaguchi, K. Matsuzaki & M. Hoshino
- Journal Title
  
  FEBS Lett.
  
  Volume: 585 Issue: 7 Pages: 1097-1102
- DOI
  10.1016/j.febslet.2011.03.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570192
[Journal Article] Ganglioside-mediated aggregation of amyloid beta-proteins (Abeta): Comparison between Abeta-(1-40) and Abeta-(1-42).2011
- Author(s)
  M. Ogawa, M. Tsukuda, T. Yamaguchi, K. Ikeda, T. Okada, Y. Yano, M. Hoshino & K. Matsuzaki
- Journal Title
  
  J. Neurochem.
  
  Volume: 116 Issue: 5 Pages: 851-857
- DOI
  10.1111/j.1471-4159.2010.06997.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570192
[Journal Article] Mechanism of amyloid beta-protein aggregation mediated by GM1 ganglioside clusters.2011
- Author(s)
  K. Ikeda, T. Yamaguchi, S. Fukunaga, M. Hoshino & Katsumi Matsuzaki
- Journal Title
  
  Biochemistry
  
  Volume: 50 Issue: 29 Pages: 6433-6440
- DOI
  10.1021/bi200771m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570192
[Journal Article] Chaperonin-encapsulation of proteins for NMR2010
- Author(s)
  S.Tanaka, Y.Kawata, G.Otting, N.E.Dixon, K.Matsuzaki, M.Hoshino
- Journal Title
  
  Biochimica et Biophysica Acta 1804
  
  Pages: 866-871
- NAID
  120001981960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687010
[Journal Article] Chaperonin-encapsulation of proteins for NMR.2010
- Author(s)
  S. Tanaka, Y. Kawata, G. Otting. N.E. Dixon, K. Matsuzaki, M. Hoshino
- Journal Title
  
  Biochim. Biophys. Acta 1804
  
  Pages: 866-871
- NAID
  120001981960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687010
[Presentation] リン脂質誘導体カクテルによる膜タンパク質の小サイズでの安定な可溶化2024
- Author(s)
  松崎勝巳; 高木麻衣; 秦綾美; 長谷綾菜; 横山あずさ; 林田幸一; 星遥華; 山崎大資; 大山侃志; 河野健一; 黒田悠介; 山岡庸介; 星野大; 矢野義明; 高須清誠日本薬学会第144年会
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18184
[Presentation] 血清アミロイドＡの線維形成における主要な構造変化2023
- Author(s)
  奥西　泰之、松崎　勝己、星野　大
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K06101
[Presentation] 血清アミロイドＡの自己凝集機構の解析・アカモクフコイダンのアミロイドβ凝集抑制機構の解析2023
- Author(s)
  星野　大、奥西　泰之、八木　寿梓
- Organizer
  第14回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Data Source
  KAKENHI-PROJECT-22K06101
[Presentation] 血清アミロイドＡのアミロイド線維形成機構の解明2023
- Author(s)
  奥西　泰之、松崎　勝己、星野　大
- Organizer
  第23回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-22K06101
[Presentation] 血清アミロイドＡのアミロイド線維形成機構の解明2023
- Author(s)
  奥西　泰之、松崎　勝己、星野　大
- Organizer
  第20回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Data Source
  KAKENHI-PROJECT-22K06101
[Presentation] 血清アミロイドＡの自己凝集機構の解析・アカモクフコイダンのアミロイドβ凝集抑制機構の解析2023
- Author(s)
  星野大、奥西泰之、八木寿梓
- Organizer
  第14回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Data Source
  KAKENHI-PROJECT-22K06101
[Presentation] Biophysical analysis of the amyloid fibril formation by serum amyloid A2022
- Author(s)
  Taishi Okunishi, Katsumi Matsuzaki and Masaru Hoshino
- Organizer
  The 4th Proteostasis and Disease Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06101
[Presentation] Inhibitory effect of fucoidan on the fibril formation by amyloid-beta peptides2022
- Author(s)
  Masaru Hoshino, Yoshinori Kato and Hisashi Yagi
- Organizer
  The 4th Proteostasis and Disease Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06101
[Presentation] Interaction between Mint3 and FIH-1 analyzed by high-resolution NMR2020
- Author(s)
  Ryo Maeda, Satoru Nagatoishi, Kouhei Tsumoto, Katsumi Matsuzaki & Masaru Hoshino
- Organizer
  第20回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-18K06151
[Presentation] Dynamic equilibrium between amyloid-β molecules required for "mature" fibril formation.2019
- Author(s)
  M. Hoshino
- Organizer
  Pavia Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06151
[Presentation] Dynamic equilibrium between oligomeric states of amyloid-β peptide studied by solution NMR2019
- Author(s)
  Masaru Hoshino
- Organizer
  The 3rd Ulm Meeting - Biophysics of Amyloid Formation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06151
[Presentation] 高分解能溶液NMRによるタンパク質の動的構造解析2019
- Author(s)
  星野　大
- Organizer
  第20回若手NMR研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06151
[Presentation] アミロイドβペプチド凝集初期過程の解析2018
- Author(s)
  星野大、中川大雅、釣　大佑、西井一郎
- Organizer
  第10回タンパク質の異常凝集とその防御・修復機構に関する研究会
- Data Source
  KAKENHI-PROJECT-18K06151
[Presentation] シャペロニンGroEのフットボール型複合体におけるリング交換反応2018
- Author(s)
  石野聡、矢野義明、河田康志、松崎勝巳、星野大
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06151
[Presentation] 高分解能溶液NMRによるアミロイドβ凝集初期過程の解析2018
- Author(s)
  中川大雅、西井一郎、松崎勝巳、星野大
- Organizer
  第18回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-18K06151
[Presentation] 転写因子Sp1とTAF4の相互作用領域のＮＭＲ解析2017
- Author(s)
  日比野　絵美、井上　倫太郎、杉山　正明、桑原　淳、松崎　勝巳、星野　大
- Organizer
  第17回日本蛋白質科学会年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-06-20
- Data Source
  KAKENHI-PROJECT-26440025
[Presentation] Interaction between intrinsically disordered regions in transcription factors Sp1 and TAF42016
- Author(s)
  E. Hibino, R. Inoue, M. Sugiyama, J. Kuwahara, K. Matsuzaki & M. Hoshino
- Organizer
  XXVIIth Internatinal Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2016-08-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440025
[Presentation] 分子シャペロン Cdc37 のリン酸化による構造転移機構2016
- Author(s)
  井濱太、山本麻実、宮田愛彦、松崎勝巳、星野大
- Organizer
  第16回日本蛋白質科学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-06-07
- Data Source
  KAKENHI-PROJECT-26440025
[Presentation] New Insights into the Reaction Mechanism of Molecular Chaperone GroE.2015
- Author(s)
  Masaru Hoshino
- Organizer
  IPR Seminar, Macromolecular Crowding and Protein Association
- Place of Presentation
  Institute for Protein Research, Osaka Univ.
- Year and Date
  2015-02-05
- Invited
- Data Source
  KAKENHI-PROJECT-26440025
[Presentation] The interaction between transcription factors Sp1 and TAF4 via the intrinsically disordered regions.2015
- Author(s)
  Masaru Hoshino
- Organizer
  Protein Structure and Function (IPR x RSC Joint Symposium)
- Place of Presentation
  オーストラリア国立大学
- Year and Date
  2015-11-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440025
[Presentation] Sp1とTAF4の天然変性領域を介した相互作用の解析2015
- Author(s)
  日比野絵美、井上倫太郎、杉山正明、桑原淳、松崎勝巳、星野大
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  徳島・あわぎんホール
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-26440025
[Presentation] Interaction between transcriptional activation domains of Sp1 and TAF4 examined by heteronuclear magnetic resonance2013
- Author(s)
  E. Hibino, J. Kuwahara, K. Matsuzaki & M. Hoshino.
- Organizer
  新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」第2回国際シンポジウム
- Place of Presentation
  理化学研究所横浜研究所交流棟ホール
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] アミロイドβペプチドの線維形成機構の解析2013
- Author(s)
  星野大
- Organizer
  R-GIROプロジェクトセミナー「蛋白質のフォールディングおよびフォールディング病発祥機構の解明のための統合研究」
- Place of Presentation
  立命館大学生命科学部・薬学部
- Year and Date
  2013-03-16
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] Revisiting the stability of an SR398/GroES chaperonin complex.2013
- Author(s)
  S. Ishino, K. Matsuzaki & M. Hoshino
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 溶液NMRによるアミロイドβペプチドの相互作用解析2013
- Author(s)
  星野大
- Organizer
  日本薬学会北陸支部特別講演会
- Place of Presentation
  富山大学杉谷キャンパス
- Year and Date
  2013-12-13
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] アミロイドβペプチドの線維形成機構の解析2013
- Author(s)
  星野　大
- Organizer
  R-GIRO プロジェクトセミナー「蛋白質のフォールディングおよびフォールディング病発祥機構の解明のための統合研究」
- Place of Presentation
  立命館大学　生命科学部・薬学部　びわこくさつキャンパス（滋賀県）
- Invited
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 転写因子 Sp1 と TAF4 の天然変性領域を介した相互作用の解析2013
- Author(s)
  星野　大9月3日～5日，ひだホテルプラザ
- Organizer
  新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」領域会議
- Place of Presentation
  ひだホテルプラザ
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] Interaction between transcriptional activation domains of Sp1 and TAF4 examined by heteronuclear magnetic resonance.2013
- Author(s)
  Emi Hibino, Jun Kuwahara, Katsumi Matsuzaki Masaru Hoshino
- Organizer
  新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」第2回国際シンポジウム
- Place of Presentation
  理化学研究所　横浜研究所交流棟ホール（神奈川県）
- Year and Date
  2013-01-23
- Data Source
  KAKENHI-PUBLICLY-24113708
[Presentation] 転写因子 Sp1 と TAF4 の天然変性領域を介した相互作用の解析2013
- Author(s)
  日比野　絵美、桑原　淳、松崎　勝巳、星野　大
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館
- Data Source
  KAKENHI-PUBLICLY-24113708
[Presentation] 転写因子Sp1とTAF4の天然変性領域を介した相互作用の解析2013
- Author(s)
  星野大
- Organizer
  新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」領域会議
- Place of Presentation
  ひだホテルプラザ
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 転写因子 Sp1 と TAF4 の天然変性領域を介した相互作用の解析2013
- Author(s)
  日比野　絵美、桑原　淳、松崎　勝巳、星野　大
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] Interaction between transcriptional activation domains of Sp1 and TAF4 examined by heteronuclear magnetic resonance.2013
- Author(s)
  Emi Hibino, Jun Kuwahara, Katsumi Matsuzaki & Masaru Hoshino
- Organizer
  新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」第2回国際シンポジウム
- Place of Presentation
  理化学研究所　横浜研究所交流棟ホール（神奈川県）
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] Revisiting the stability of an SR398/GroES chaperonin complex2013
- Author(s)
  S. Ishino, K. Matsuzaki & M. Hoshino.
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 転写因子Sp1とTAF4の天然変性領域を介した相互作用の解析2013
- Author(s)
  日比野絵美,桑原淳,松崎勝巳,星野大
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 転写因子 Sp1 と TAF4 の天然変性領域を介した相互作用の解析2013
- Author(s)
  星野　大
- Organizer
  新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」領域会議
- Place of Presentation
  ひだホテルプラザ
- Data Source
  KAKENHI-PUBLICLY-24113708
[Presentation] アミロイドβペプチドの線維形成機構の解析2013
- Author(s)
  星野　大
- Organizer
  R-GIRO プロジェクトセミナー「蛋白質のフォールディングおよびフォールディング病発祥機構の解明のための統合研究」
- Place of Presentation
  立命館大学　生命科学部・薬学部　びわこくさつキャンパス（滋賀県）
- Invited
- Data Source
  KAKENHI-PUBLICLY-24113708
[Presentation] Revisiting the stability of an SR398/GroES chaperonin complex.2013
- Author(s)
  S. Ishino, K. Matsuzaki & M. Hoshino
- Organizer
  第13回日本蛋白質科学会年会
- Place of Presentation
  とりぎん文化会館
- Data Source
  KAKENHI-PUBLICLY-24113708
[Presentation] 分子シャペロンカプセル化システムの構築2012
- Author(s)
  星野大
- Organizer
  大阪大学蛋白質研究所セミナー「分子シャペロンの機能発現の新展開と細胞制御」
- Place of Presentation
  大阪大学蛋白質研究所
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 分子シャペロンカプセル化システムの構築2012
- Author(s)
  星野　大
- Organizer
  大阪大学蛋白質研究所セミナー「分子シャペロンの機能発現の新展開と細胞制御」
- Place of Presentation
  大阪大学蛋白質研究所（大阪府）
- Invited
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 分子シャペロンカプセル化システムの構築2012
- Author(s)
  星野　大
- Organizer
  大阪大学蛋白質研究所セミナー「分子シャペロンの機能発現の新展開と細胞制御」
- Place of Presentation
  大阪大学蛋白質研究所（大阪府）
- Year and Date
  2012-11-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-24113708
[Presentation] グルタミンリッチ型転写活性化ドメインの相互作用解析2012
- Author(s)
  星野大
- Organizer
  新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」領域会議
- Place of Presentation
  北広島クラッセホテル
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 転写因子Sp1の転写活性化ドメイン間相互作用の解明2011
- Author(s)
  平松直子,日比野絵美,松崎勝巳,桑原淳,星野大
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 転写因子Sp1の転写活性化ドメイン間相互作用の解明2011
- Author(s)
  平松直子,日比野絵美,松崎勝巳,桑原淳,星野大
- Organizer
  第9回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  ホテル箱根アカデミー
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] Interaction between isolated transcriptional activation domains of Sp1 revealed by heteronuclear magnetic resonance.2011
- Author(s)
  Naoko Hiramatsu, Emi Hibino, Katsumi Matsuzaki, Jun Kuwahara and Masaru Hoshino
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府）
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 転写因子 Sp1 の転写活性化ドメイン間相互作用の解明2011
- Author(s)
  平松直子、日比野絵美、松崎勝巳、桑原淳、星野大
- Organizer
  次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  ホテル箱根アカデミー（神奈川県）
- Data Source
  KAKENHI-PROJECT-23570192
[Presentation] 分子シャペロンカプセル化システムの構築2009
- Author(s)
  増原泰英, 河田康志, 松崎勝巳, 星野大
- Organizer
  第48回nmr討論会
- Place of Presentation
  九州大学馬出病院キャンパス
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-19687010
[Presentation] 溶液nmrによる凝集性タンパク質の新規構造解析法2009
- Author(s)
  田中慎治, 河田康志, 松崎勝巳, 星野大
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19687010
[Presentation] 溶液NMRによる凝集性タンパク質の新規構造解析法2009
- Author(s)
  田中慎治, 河田康志, 松崎勝巳, 星野大
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19687010
[Presentation] 分子シャペロンカプセル化システムの構築2009
- Author(s)
  増原泰英, 河田康志, 松崎勝巳, 星野大
- Organizer
  第48回 NMR討論会
- Place of Presentation
  九州大学馬出病院キャンパス
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-19687010
[Presentation] 溶液高分解能nmrによる凝集性タンパク質の新規構造解析法の開発2008
- Author(s)
  田中慎治, 河田康志, 松崎勝巳, 星野大
- Organizer
  日本生物物理学会第46回年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-19687010
[Presentation] 溶液高分解能NMRによる凝集性タンパク質の新規構造解析法の開発2008
- Author(s)
  田中慎治, 河田康志, 松崎勝巳, 星野大
- Organizer
  日本生物物理学会第46回年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-19687010
[Presentation] Aggregation mechanism of amyloid-beta peptide revealed by solution state NMR.
- Author(s)
  Masaru Hoshino
- Organizer
  The IPR seminar: JSPS Japan Hungary Joint Seminar
- Place of Presentation
  Institute for Protein Research, Osaka Univ.
- Year and Date
  2014-11-17 – 2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-26440025
[Presentation] The interaction between transcription factors Sp1 and TAF4 via the intrinsically disordered regions.
- Author(s)
  Emi Hibino, R. Inoue, M. Sugiyama, J. Kuwahara, K. Matsuzaki & Masaru Hoshino
- Organizer
  日本生物物理学会　第52回年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26440025
[Presentation] Effect of C-terminal truncation of chaperonin GroEL on the yield of an in-cage folding of GFP.
- Author(s)
  So Ishino, Y. Kawata, H. Taguchi, K. Matsuzaki & Masaru Hoshino
- Organizer
  日本生物物理学会　第52回年会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26440025

1. MATSUZAKI Katsumi (00201773)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. YANO Yoshiaki (60402799)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. GOTO Yuji (40153770)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. IKEGAMI Takahisa (20283939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. KAWATA Yasushi (40177697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KUWATA Kazuo (00170142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NAIKI Hironobu (10227704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 河野健一 (70732874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. HIBINO Emi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. ARIYOSI Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 宮田愛彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 杉山正明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 松崎勝己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 白川昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 杤尾豪人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hoshino Masaru 星野 大

星野 大 ホシノ マサル

MASARU Hoshino 星野 大

HOSHINO Masaru 星野 大

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Mechanism of molecular recognition between intrinsically disordered regions.Principal Investigator

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NMR analysis of amyloid-beta soluble oligomer encapsulated in reverse micellePrincipal Investigator

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Molecular mechanism of interaction between transcriptional factors Sp1 and TAF4.Principal Investigator

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グルタミンリッチ型転写活性化ドメインの相互作用解析Principal Investigator

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NMR analysis of amyloid beta-oligomer by using molecular chaperone encapsulation system.Principal Investigator

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Novel chaperonin-encapsulation system for aggregation-prone proteins.Principal Investigator

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高分解能NMRによるアミロイド線維の構造解析Principal Investigator

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高分解能NMRによるGroE-基質複合体の直接観測Principal Investigator

Hoshino Masaru 星野大

星野大ホシノマサル

MASARU Hoshino 星野大

HOSHINO Masaru 星野大