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Sowa Yoshihiro  曽和 義広

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SOWA Yoshihiro  曽和 義広

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Researcher Number 70315935
Other IDs
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 特任教授
2012 – 2020: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
2014: 京都府立医科大学, 医学研究科, 准教授
2008 – 2012: Kyoto Prefectural University of Medicine, 医学研究科, 准教授
2003 – 2008: 京都府立医科大学, 医学研究科, 講師
2002: Kyoto Prefectural University of Medicine, Department of Preventive Medicine, Lecturer, 医学部, 講師
2000 – 2002: 京都府立医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Hygiene / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Hygiene and public health / Hygiene / Biological Sciences
Except Principal Investigator
Hygiene / Hygiene / Hygiene and public health / Digestive surgery / Biological Sciences / Science and Engineering / Digestive surgery
Keywords
Principal Investigator
p21 / sulforaphane / WAF1 / がん / ドラッグ・リパーパシング / artepillin C / fucoxantin / apigenin / genistein / スクリーニング … More / 食品成分 / CCAAT / M期 / NF-Y / アポトーシス / G2 / 酪酸 / ヒストン脱アセチル化酵素阻害剤 / 化学予防 / タンパク質合成阻害 / 免疫調整 / 抗炎症 / マクロライド / RB / 予防 / p130 / p107 / RB非依存 / cell-basedスクリーニング / RBファミリー / molecular-targeting cancer prevention / food factor / cancer prevention / Gadd45 / p53 / アピゲニン / ゲニステイン / TRAIL / DR5 / がん予防 / 分子標的癌予防 / 発がん予防 / EZH2 / ヒストンメチル化 / エピジェネティクス / MAPK経路 / PI3K/Akt経路 / PI3K阻害剤 / fenofibrate / thymidylate synthase / グルタチオン / Reactive oxygen species(ROS) / ミトコンドリア / Reactive oxygen species (ROS) / HDAC阻害剤 / DNAメチル化 / HDAC 阻害剤 / microRNA / DNA メチル化 / 悪性中皮腫 / dially trisulfide / CDK / 併用 / reactive oxygen species / diallyl trisulfide / 予防医学 / telomerase / Oct-1 / M期停止 / gadd45 / ヒストン脱アセチル化酵素 / 食物繊維 / 転写活性化 / 転写抑制 / 抗癌剤 / 細胞周期 / Sp3 / プロモーター … More
Except Principal Investigator
p53 / gadd45 / TRAIL / 癌 / ケルセチン / NF-Y / WAF1 / p21 / p27 / p15 / DR5 / プロモーター / p18 / TPA / 酪酸 / RB / Oct-1 / promoter / フラボノイド / HDAC阻害剤 / ルテオリン / p16 / 癌抑制遺伝子 / ゲニステイン / アポトーシス / p19 / Sp3 / 分子予防 / がん予防 / mac25 / luciferase / TSA / Vitamin D_3 / 予防 / フラボン / エピジェネティクス / 食品成分 / 癌予防 / DNAメチル化 / アピゲニン / リ・フラウメニ症候群 / 細胞周期 / CCAAT / ヒストン脱アセチル化酵素阻害剤 / 子宮頸がん / E7 / HPV / 抗酸化能 / 飲料 / 抗炎症 / 抗酸化 / 天然物 / RB再活性化 / 分子標的予防法 / I3C / butyrate / インドール-3-カービノール / quercetin / flavonoids / Sodium Butyrate / ビタミンD_3受容体 / mac25遺伝子 / ビタミンD_3 / uv / Vitamin D3 / Oct1 / 遺伝子修復 / UV / 転写因子 / HeLa / UVpromoter / histone deacetylase inhibitor / prevention / cancer / 紫外線 / gadd45遺伝子 / Δ^<12>-プロスタグランディンJ_2 / リ-フラウメニ症侯群 / Sp1 / SAHA / セストン脱アセチル化酵素阻害剤 / WAP1 / 分子標的予防 / 科学予防 / HDAC阻害 / 放射線 / 5-FU / 食道癌 / エピジェネテクス / GADD45 / miR-16 / miR-15 / Bcl-2 / miR-222 / miR-221 / miR-34b/c / メチル化 / flavone / G1期停止 / E2F / G1 期停止 / miR-34a / 併用 / INK4B / INK4A / ヒストンアセチル化 / Crytolepin / MEK阻害剤 / スルフォラファン / ビタミンD3 / スプライシング / 食品 / 発現制御 / 遺伝子 / MEK / MAPK / 家族性メラノーマ / p53-RB経路 / がん / テーラーメイド予防 / ヘリコバクター・ピロリ / CDK2活性 / 細胞周期プロファイリング / 発癌促進物質 / 発癌抑制物質 / クルクミン / PKC / CDK / Siah-1 / 環境発癌要因 / 発癌プロモーター / 環境発癌因子 / 転写活性化 / 転写抑制 / 抗癌剤 / telomerase / M期 / G2 Less
  • Research Projects

    (27 results)
  • Research Products

    (103 results)
  • Co-Researchers

    (25 People)
  •  Development of chemoprevention of cancer by drug repurposing with the macrolidesPrincipal Investigator

    • Principal Investigator
      曽和 義広
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of novel cancer prevention strategy by the enhancement of RB family proteinsPrincipal Investigator

    • Principal Investigator
      Sowa Yoshihiro
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58020:Hygiene and public health-related: including laboratory approach
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Molecular-targeting prevention against human papilloma virus-positive cervical cancer

    • Principal Investigator
      Sakai Toshiyuki
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene and public health
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Application of molecular-targeting cancer prevention to human intervention study.

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene and public health
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of novel molecular-targeting cancer prevention with histone methylation inhibitory dietary compoundPrincipal Investigator

    • Principal Investigator
      Sowa Yoshihiro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene and public health
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Tailor-made molecular targeted chemoradiotherapy for esophageal cancer

    • Principal Investigator
      FUJIWARA Hitoshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Screening for the suppressor of the expression of thymidylate synthasePrincipal Investigator

    • Principal Investigator
      SOWA Yoshihiro
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of micrRNA-targeting cancer prevention

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of cancer prevention based on the molecular mechanism against malignant mesothelioma.Principal Investigator

    • Principal Investigator
      SOWA Yoshihiro
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  GADD45を標的とした新規癌予防エピジェネティクス

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  TRAILとDR5を標的とした癌の「分子標的併用療法」の開発

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Investigation of combined effects of food factors for cancer preventionPrincipal Investigator

    • Principal Investigator
      SOWA Yoshihiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  エピジェネティックに失活した癌抑制遺伝子を標的とした新規癌予防法の開発

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  癌抑制遺伝子群の発現を調節する癌治療薬シーズの探索

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  ヒト環境発癌分子を標的とした新規発癌抑制物質スクリーニング系の構築

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Research on a selection reference of chemopreventive agents for cancer and a development of tailor-made medicine for cancer prevention

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  癌抑制遺伝子のRNAスプライシングによる調節機構を応用した癌予防法の開発

    • Principal Investigator
      中西 涼子
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  新規細胞周期プロファイリング装置を用いた胃前癌病変のリスク診断と癌予防への応用

    • Principal Investigator
      KAMIYAMA Jun
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Meiji College of Oriental Medicine
  •  Study of the mechanisms of cancer prevention by food factors for personalized preventionPrincipal Investigator

    • Principal Investigator
      SOWA Yoshihiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  種々の環境発癌因子の標的分子の同定―「分子標的予防法」に向けての基礎的研究

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Basic research for ‘gene-regulating chemoprevention' by using food factors

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  食物繊維由来の酪酸による大腸癌に対する予防効果の作用機構の検討Principal Investigator

    • Principal Investigator
      曽和 義広
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  ヒストン脱アセチル化酵素阻害剤によるP21/WAF1遺伝子誘導機構の解析Principal Investigator

    • Principal Investigator
      曽和 義広
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  大腸癌に対するヒストン脱アセチル化酵素阻害剤の抗腫瘍効果の作用機構の解析

    • Principal Investigator
      酒井 敏行
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of the new cancer preventing method with the ingredient of the food of Kyoto

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for University and Society Collaboration
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of specific prevention against DNA damage caused by environment

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of specific prevention against people with high susceptibility for cancer and general carcinogenesis

    • Principal Investigator
      SAKAI Toshiyuki
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2019 2018 2017 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book

  • [Book] バイオ医薬の開発技術とシース2009

    • Author(s)
      曽和義広
    • Publisher
      シーェムシー出版
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Book] バイオ医薬の開発技術とシーズ2009

    • Author(s)
      曽和義広
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Book] アンチエイジング・ヘルスフード2008

    • Author(s)
      曽和義広
    • Total Pages
      7
    • Publisher
      サイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Book] アンチエイジング・ヘルスフード2008

    • Author(s)
      曽和義広, 他
    • Publisher
      サイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-19659151
  • [Book] アンチエイジング・ヘルスフード2008

    • Author(s)
      曽和義広, 他
    • Publisher
      サイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Book] アンチエイジング・ヘルスフード2008

    • Author(s)
      曽和義広, 他
    • Total Pages
      7
    • Publisher
      サイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Book] アンチエイジング・ヘルスフード2008

    • Author(s)
      曽和義広, 他
    • Total Pages
      7
    • Publisher
      サイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-20015040
  • [Journal Article] Cycloartenyl ferulate and β-sitosteryl ferulate, steryl ferulates of γ-oryzanol, suppressed intracellular reactive oxygen species in the cell-based system.2019

    • Author(s)
      Yasuda S, Sowa Y, Hashimoto H, Nakagami T, Tsuno T, Sakai T.
    • Journal Title

      Journal of Oleo Science

      Volume: 印刷中

    • NAID

      130007686318

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02529
  • [Journal Article] The novel HDAC inhibitor OBP-801/YM753 enhances the effects of 5-fluorouracil with radiation on esophageal squamous carcinoma cells2014

    • Author(s)
      Furutani A1, Sowa Y, Fujiwara H, Otsuji E, Sakai T
    • Journal Title

      Oncol Res.

      Volume: 21 Issue: 5 Pages: 281-286

    • DOI

      10.3727/096504014x13890370410249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591958
  • [Journal Article] Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation.2013

    • Author(s)
      Todo M, Horinaka M, Tomosugi M, Tanaka R, Ikawa H, Sowa Y, Ishikawa H, Fujiwara H, Otsuji E, Sakai T
    • Journal Title

      Oncol Rep.

      Volume: 30 Issue: 5 Pages: 2379-2384

    • DOI

      10.3892/or.2013.2713

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591958, KAKENHI-PROJECT-24659304, KAKENHI-PROJECT-24689031
  • [Journal Article] Novel MEK inhibitor trametinib and other retinoblastoma gene (RB)-reactivating agents enhance efficacy of 5-fluorouracil on human colon cancer cells2013

    • Author(s)
      Watanabe M, Sowa Y, Yogosawa M, Sakai T.
    • Journal Title

      Cancer Sci.

      Volume: Epub ahead of print Issue: 6 Pages: 687-693

    • DOI

      10.1111/cas.12139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591958, KAKENHI-PROJECT-24659305
  • [Journal Article] Perillyl alcohol causes G1 arrest through p15INK4band p21WAF1/Cip1induction2013

    • Author(s)
      Koyama M, Sowa Y, Hitomi T, Iizumi Y, Watanabe M, Taniguchi T, Ichikawa M, Sakai T
    • Journal Title

      Oncol Rep

      Volume: Vol. 29、 No. 2 Issue: 2 Pages: 779-784

    • DOI

      10.3892/or.2012.2167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23590741, KAKENHI-PROJECT-23689036
  • [Journal Article] Retinoblastoma gene-independent G1 phase arrest by flavone, phosphatidylinositol 3-kinase inhibitor, and histone deacetylase inhibitor2012

    • Author(s)
      Tomosugi M, Sowa Y, Yasuda S, Tanaka R, te Riele H, Ikawa H, Koyama M, Sakai T
    • Journal Title

      Cancer Sci.

      Volume: Vol. 103、 No. 12 Issue: 12 Pages: 2139-2143

    • DOI

      10.1111/cas.12012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23790670, KAKENHI-PROJECT-24591958
  • [Journal Article] Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells2012

    • Author(s)
      Izutani Y, Yogosawa S, Sowa Y, Sakai T
    • Journal Title

      Int J Oncol

      Volume: Vol. 40、 No. 3 Pages: 816-824

    • DOI

      10.3892/ijo.2011.1246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249042, KAKENHI-PROJECT-23790669
  • [Journal Article] The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells.2012

    • Author(s)
      Jun Fujiwara, Yoshihiro Sowa, Mano Horinaka, Makoto Koyama, Miki Wakada, Tsuneharu Miki, Toshiyuki Sakai
    • Journal Title

      International Journal of Oncology

      Volume: 40 Pages: 1483-1491

    • DOI

      10.3892/ijo.2012.1353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659336, KAKENHI-PROJECT-24591958
  • [Journal Article] HDAC阻害剤の開発状況2010

    • Author(s)
      曽和義広
    • Journal Title

      癌と化学療法

      Volume: 37(9) Pages: 1665-1668

    • Data Source
      KAKENHI-PROJECT-21390192
  • [Journal Article] Cyclin-dependent kinase inhibitor SU9516 enhances sensitivity to methotrexate in human T-cell leukemia Jurkat cells.2010

    • Author(s)
      Uchiyama H, Sowa Y, Wakada M, Yogosawa M, Nakanishi R, Horinaka M, Shimazaki C, Taniwaki M, Sakai T.
    • Journal Title

      Cancer Sci.

      Volume: 101 Pages: 728-734

    • NAID

      10026589738

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Journal Article] Histone deacetylase inhibitors and 15-deoxy-△^<12,14>-prostaglandin J_2 synergistically induce apoptosis.2010

    • Author(s)
      Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
    • Journal Title

      Clin Cancer Res. 16

      Pages: 2320-2332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Journal Article] A novel MEK1/2 inhibitor induces G1/S cell cycle arrest in human fibrosarcoma cells.2010

    • Author(s)
      Matsui TA, Murata H, Sowa Y, Sakabe T, Koto K, Horie N, Tsuji Y, Sakai T, Kubo T.
    • Journal Title

      Oncol Rep.

      Volume: 24 Pages: 329-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Journal Article] Histone deacetylase inhibitors and 15-deoxy-Δ^<12,14>-Prostaglandin J_2 synergistically induce apoptosis.2010

    • Author(s)
      Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
    • Journal Title

      Clin Cancer Res.

      Volume: 16 Pages: 2320-2332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Journal Article] Histone deacetylase inhibitors and 15-deoxy-・12,14-prostaglandin J2 synergistically induce apoptosis2010

    • Author(s)
      Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T
    • Journal Title

      Clin Cancer Res.

      Volume: Vol. 16、No. 8 Issue: 8 Pages: 2320-2332

    • DOI

      10.1158/1078-0432.ccr-09-2301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249042
  • [Journal Article] Insight into estrogenicity of phytoestrogens using in silico simulation2009

    • Author(s)
      Sugiyama H, Kumamoto T, Suganami A, Nakanishi W, Sowa Y, Takiguchi M, Ishikawa T, Tamura Y
    • Journal Title

      Biochemical and Biophysical Research Communications 379(1)

      Pages: 139-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Journal Article] Insight into estrogenicity of phytoestrogens using in silico simulation2009

    • Author(s)
      Sugiyama H, Sowa Y(他6名)
    • Journal Title

      Biochem Biophys Res Commun 379

      Pages: 139-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] 発癌の分子機構に基づいた癌の“分子標的予防"研究2008

    • Author(s)
      曽和義広, 他
    • Journal Title

      医学のあゆみ 227(2)

      Pages: 147-148

    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] 発癌の分子機構に基づいた癌の“分子標的予防"研究2008

    • Author(s)
      曽和義広, 他
    • Journal Title

      医学のあゆみ 227(2)

      Pages: 147-148

    • Data Source
      KAKENHI-PROJECT-19590593
  • [Journal Article] 発癌の分子機構に基づいた癌の“分子標的予防"研究2008

    • Author(s)
      曽和義広, 他
    • Journal Title

      医学のあゆみ 227(2)

      Pages: 147-148

    • Data Source
      KAKENHI-PROJECT-19659151
  • [Journal Article] CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells.2008

    • Author(s)
      Takagi K, Sowa Y, Cevik OM, Nakanishi R, Sakai T
    • Journal Title

      International Journal of Oncology 32(3)

      Pages: 1105-1111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Journal Article] a novel histone deacetylase inhibitor, exhibits antitumor activity with selective, sustained accumulation of acetylated histones in tumors in the WiDr xenograft model2008

    • Author(s)
      Shindoh N, Sowa Y(他13名), Sakai T(他13名)YM753
    • Journal Title

      Int J Oncol. 32

      Pages: 545-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] 発癌の分子機構に基づいた癌の"分子標的予防"研究2008

    • Author(s)
      曽和義広、酒井敏行
    • Journal Title

      医学のあゆみ 227(2)

      Pages: 147-148

    • Data Source
      KAKENHI-PROJECT-19590593
  • [Journal Article] CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells2008

    • Author(s)
      Takagi K, Sowa Y, Cevik OM, Nakanishi R, Sakai T
    • Journal Title

      Int J Oncol. 32

      Pages: 1105-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Smenospongine, a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leulemia cells2008

    • Author(s)
      Kong D, Aoki S, Sowa Y, Sakai T, Kobayashi M
    • Journal Title

      Marine Drugs 6(3)

      Pages: 480-488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Journal Article] a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leukemia cells2008

    • Author(s)
      Kong D, Aoki S, Sowa Y, Sakai T, Kobayashi M. Smenospongine
    • Journal Title

      Mar Drugs 6

      Pages: 480-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] 発癌の分子機構に基づいた癌の"分子標的予防"研究2008

    • Author(s)
      曽和義広, 他
    • Journal Title

      医学のあゆみ 227(2)

      Pages: 147-148

    • Data Source
      KAKENHI-PROJECT-20015040
  • [Journal Article] Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo2007

    • Author(s)
      Matsui TA, Murata H, Sakabe T, Sowa Y, Horie N, Nakanishi R, Sakai T, Kubo T
    • Journal Title

      Oncol Rep. 18

      Pages: 1263-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Identification of JTP-70902, a p15^<INK4b>-inductive compound, as a novel MEK1/2 inhibitor2007

    • Author(s)
      Yamaguchi T, Yoshida T, Kurachi R, Kakegawa J, Hori Y, Nanayama T, Hayakawa K, Abe H, Takagi K, Matsuzaki Y, Koyama M, Yogosawa S, Sowa Y, Yamori T, Tajima N, Sakai T
    • Journal Title

      Cancer Sci. 98

      Pages: 1809-16

    • NAID

      10020119466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo.2007

    • Author(s)
      Matsui TA, Murata H, Sakabe T, Sowa Y, Horie N, Nakanishi R, Sakai T, Kubo T
    • Journal Title

      Oncology Reports 18(5)

      Pages: 1263-1268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Journal Article] The plant alkaloid cryptolepine induces p21^<WAF1/CIP1> and cell cycle arrest in a human osteosarcoma cell line2007

    • Author(s)
      Matsui TA, Sowa Y(他8名), Sakai T(他8名)
    • Journal Title

      Int J Oncol. 31

      Pages: 915-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] The plant alkaloid cryptolepine induces p21^<WAF1/CIP1> and cell cycle arrest in a human osteosarcoma cell line.2007

    • Author(s)
      Matsui TA, Sowa Y, Murata H, Takagi K, Nakanishi R, Aoki S, Yoshikawa M, Kobayashi M, Sakabe T, Kubo T, Sakai T
    • Journal Title

      International Journal of Oncology 31(4)

      Pages: 915-922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Journal Article] A novel synthetic drug, LB-18, closely related to lembehyne-A derived from a marine sponge, induces caspase-independent cell death to human neuroblastoma cells2006

    • Author(s)
      Izumi M, Yogosawa S, Aoki S, Watanabe H, Kamiyama J, Takahara Y, Sowa Y, Kobayashi M, Hosoi H, Sugimoto T, Sakai T
    • Journal Title

      Int J Oncol. 29

      Pages: 169-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Aaptamine, a spongean alkaloid, activates p21 promoter in a p53-independent manner2006

    • Author(s)
      Aoki S, Kong D, Suna H, Sowa Y, Sakai T, Setiawan A, Kobayashi M
    • Journal Title

      Biochem Biophys Res Commun. 342

      Pages: 101-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Sulforaphane enhances TRAIL-induced apoptosis through the induction of DR5 expression in human osteosarcoma cells2006

    • Author(s)
      Matsui TA, Sowa Y, Yoshida T, Murata H, Horinaka M, Wakada M, Nakanishi R, Sakabe T, Kubo T, Sakai T
    • Journal Title

      Carcinogenesis. 27

      Pages: 1768-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Artepillin C in Brazilian propolis induces G_0/G_1 arrest via stimulation of Cip1/p21 expression in human colon cancer cells2005

    • Author(s)
      Shimizu K, Das SK, Hashimoto T, Sowa Y, Yoshida T, Sakai T, Matsuura Y, Kanazawa K
    • Journal Title

      Mol Carcinog. 44

      Pages: 293-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Inhibitory effects of cancer cell proliferation by novel histone deacetylase inhibitors involve p21/WAF1 induction and G2/M arrest2005

    • Author(s)
      Maeda T, Nagaoka Y, Kawai Y, Takagaki N, Yasuda C, Yogosawa S, Sowa Y, Sakai T, Uesato S
    • Journal Title

      Biol Pharm Bull. 28

      Pages: 849-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Fucoxanthin induces cell cycle arrest at G_0/G_1 phase in human colon carcinoma cells through up-regulation of p21^<WAF1/Cip1>2005

    • Author(s)
      Das SK, Hashimoto T, Shimizu K, Yoshida T, Sakai T, Sowa Y, Komoto A, Kanazawa K
    • Journal Title

      Biochim Biophys Acta. 1726

      Pages: 328-35

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] A new cancer diagnostic system based on a CDK profiling technology2005

    • Author(s)
      Ishihara H, Sowa Y(他16名), Sakai T(他16名)
    • Journal Title

      Biochem Biophys Acta. 1741

      Pages: 226-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway.2005

    • Author(s)
      Takagaki, N., Sowa, Y., Oki, T., Nakanishi, R., Yogosawa, S., Sakai, T.
    • Journal Title

      International Journal of Oncology 26

      Pages: 185-189

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] Apigenin induces cell cycle arrest and p21/WAF1 expression in a p53-independent pathway2005

    • Author(s)
      Takagaki N, Sowa Y, Oki T, Nakanishi R, Yogosawa S, Sakai T
    • Journal Title

      Int J Oncol. 26

      Pages: 185-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Journal Article] Genistein induces gadd45 gene and G2/M cell cycle arrest in the DU145 human prostate cancer cell line.2004

    • Author(s)
      Oki, T., Sowa, Y., Hirose, T., Takagaki, N., Horinaka, M., Nakanishi, R., Yasuda, C., Yoshida, T., Kanazawa, M., Satomi, Y., Nishino, H., Miki, T., Sakai, T.
    • Journal Title

      FEBS Letters 577

      Pages: 55-59

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Journal Article] p53-independent induction of Gadd45 by histone deacetylase inhibitor : coordinate regulation by transcription factors Oct-1 and NF-Y.2003

    • Author(s)
      Hirose, T., Sowa, Y., Takahashi, S., Saito, S., Yasuda, C., Shindo, N., Furuichi, K., Sakai, T.
    • Journal Title

      Oncogene 22

      Pages: 7762-7773

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370126
  • [Presentation] 新規エピゲノム併用療法の開発2018

    • Author(s)
      曽和義広、酒井敏行
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H02529
  • [Presentation] 新規セサミノール結合蛋白質ANT2によるcyclin D1の多面的制御機構の解明2018

    • Author(s)
      渡邉元樹、飯泉陽介、曽和義広、酒井敏行
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-15H02529
  • [Presentation] セサミノール結合タンパク質ANT2の発見がもたらすcyclin D1の多面的制御機構の解明2018

    • Author(s)
      渡邉元樹、飯泉陽介、助野真由美、曽和義広、酒井敏行
    • Organizer
      第17回分子予防環境医学研究会
    • Data Source
      KAKENHI-PROJECT-15H02529
  • [Presentation] セサミノール結合タンパク質ANT2の発見がもたらす新たな細胞周期調節機構の解明2018

    • Author(s)
      渡邉元樹、飯泉陽介、助野真由美、曽和義広、酒井敏行
    • Organizer
      第88回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H02529
  • [Presentation] がんの分子標的予防の実現に向けて2018

    • Author(s)
      曽和義広
    • Organizer
      第88回日本衛生学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H02529
  • [Presentation] The strategy of molecular-targeting cancer prevention (がんの分子標的予防戦略)2017

    • Author(s)
      堀中真野, 飯泉陽介, 渡邉元樹, 増田光治, 曽和義広, 酒井敏行
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H02529
  • [Presentation] 新規MEK阻害剤trametinibなどによるRB再活性化により大腸癌細胞に対する5-FU感受性が増強される2013

    • Author(s)
      渡邉元樹、曽和義広、酒井敏行
    • Organizer
      日本がん分子標的治療学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2013-06-14
    • Data Source
      KAKENHI-PROJECT-24659305
  • [Presentation] フラボンや分子標的薬による RB 非依存的なG1 期停止の誘導2013

    • Author(s)
      友杉充宏、曽和義広、酒井敏行
    • Organizer
      日本衛生学会学術総会
    • Place of Presentation
      金沢大学鶴間キャンパス(金沢)
    • Year and Date
      2013-03-25
    • Data Source
      KAKENHI-PROJECT-21249042
  • [Presentation] Novel MEK inhibitor trametinib and other RB-reactivating agents enhance efficacy of 5-fluorouracil on human colon cancer cells2013

    • Author(s)
      Motoki Watanabe, Yoshihiro Sowa, Toshiyuki Sakai
    • Organizer
      日本癌学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2013-10-03
    • Data Source
      KAKENHI-PROJECT-24659305
  • [Presentation] フラボンや分子標的薬による RB 非依存的なG1 期停止の誘導2012

    • Author(s)
      友杉充宏、曽和義広、安田周祐、小山真、酒井敏行
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-21249042
  • [Presentation] フラボンによる RB 非依存的な G1 期における細胞周期停止の誘導2011

    • Author(s)
      友杉充宏、曽和義広、酒井敏行
    • Organizer
      第81回日本衛生学会学術総会
    • Place of Presentation
      昭和大学(誌上開催)
    • Year and Date
      2011-03-27
    • Data Source
      KAKENHI-PROJECT-21249042
  • [Presentation] フラボンによるRB非依存的なG1期における細胞周期停止の誘導2011

    • Author(s)
      友杉充宏、曽和義広、酒井敏行
    • Organizer
      第81回日本衛生学会学術総会
    • Place of Presentation
      昭和大学(誌上開催)
    • Year and Date
      2011-03-27
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] 大腸癌細胞株に対するインドール-3-カルビノールとガランギンの併用による細胞死増強2011

    • Author(s)
      与五沢真吾、渡部公綱、瀧澤香織、曽和義広、酒井敏行
    • Organizer
      第10回分子予防環境医学研究会大会
    • Place of Presentation
      京都府立医科大学
    • Year and Date
      2011-01-21
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] クルクミンの半量体デヒドロジンゲロンによる細胞増殖抑制効果2011

    • Author(s)
      与五沢真吾、安田周祐、山田恭正、曽和義広、酒井敏行
    • Organizer
      第81回日本衛生学会学術総会
    • Place of Presentation
      昭和大学(誌上開催)
    • Year and Date
      2011-03-27
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] 大腸癌細胞株に対するブラシニンの細胞周期停止効果とその分子メカニズム2011

    • Author(s)
      泉谷泰行、与五沢真吾、曽和義広、酒井敏行
    • Organizer
      第10回分子予防環境医学研究会大会
    • Place of Presentation
      京都府立医科大学
    • Year and Date
      2011-01-22
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] フラボンによる RB 非依存的 G1 期停止の誘導2011

    • Author(s)
      友杉充宏、曽和義広、酒井敏行
    • Organizer
      がん予防大会 2011 京都
    • Place of Presentation
      京都府立医科大学図書館ホール(京都)
    • Year and Date
      2011-06-11
    • Data Source
      KAKENHI-PROJECT-21249042
  • [Presentation] ヒト白血病におけるCDK阻害薬によるMTX感受性増強についての検討2010

    • Author(s)
      内山人二、曽和義広、堀中真野、島崎千尋、谷脇雅史、酒井敏行
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際コンベンションセンター
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] HDAC阻害剤と15-deoxy-Δ^<12,14>-prostaglandin J_2の併用療法は相乗的にアポトーシスを引き起こす2010

    • Author(s)
      小山真、ゴーダアハメッド、堀中真野、与五沢真吾、曽和義広、酒井敏行
    • Organizer
      第14回日本がん分子標的治療学会学術集会
    • Place of Presentation
      タワーホール船堀
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] Histone deacetylase inhibitors and 15-deoxy-Δ^<12,14>-prostaglandin J_2 synergistically induce apoptosis.2010

    • Author(s)
      Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
    • Organizer
      AACR 101^<st> Annual Meeting 2010
    • Place of Presentation
      Walter E.Washington Convention Center
    • Year and Date
      2010-04-21
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] インドールー3-カルビノールとガランギンの併用による細胞死増強効果2010

    • Author(s)
      与五沢真吾、渡部公綱、瀧澤香織、曽和義広、酒井敏行
    • Organizer
      第80回日本衛生学会学術総会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2010-05-10
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] HDAC阻害剤と15-deoxy-Δ^<12,14>-prostaglandin J_2は相乗的にアポトーシスを引き起こす2010

    • Author(s)
      小山真、泉谷泰行、ゴーダアハメッド、堀中真野、友杉充宏、中村吉隆、与五沢真吾、曽和義広、酒井敏行
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際コンベンションセンター
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] Histone deacetylase inhibitors and 15-deoxy-△^<12,14)-prostaglandin J_2 synergistically induce apoptosis.2010

    • Author(s)
      Koyama M, Izutani Y, Goda AE, Matsui TA, Horinaka M, Tomosugi M, Fujiwara J, Nakamura Y, Wakada M, Yogosawa S, Sowa Y, Sakai T.
    • Organizer
      AACR 101^<st> annual meeting 2010
    • Place of Presentation
      Walter E.Washington convention center
    • Year and Date
      2010-04-21
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] CDK阻害剤によるDHFR発現抑制を介したMTX感受性増強についての検討2010

    • Author(s)
      内山人二、曽和義広、堀中真野、酒井敏行
    • Organizer
      第14回日本がん分子標的治療学会学術集会
    • Place of Presentation
      タワーホール船堀
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] 大腸癌細胞株に対するブラシニンの細胞周期停止効果とその分子メカニズム2010

    • Author(s)
      泉谷泰行、与五沢真吾、渡部公綱、曽和義広、酒井敏行
    • Organizer
      第80回日本衛生学会学術総会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2010-05-10
    • Data Source
      KAKENHI-PROJECT-21659159
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2009

    • Author(s)
      曽和義広, 他
    • Organizer
      分子予防環境医学研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-01-23
    • Data Source
      KAKENHI-PROJECT-19659151
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2009

    • Author(s)
      曽和義広, 他
    • Organizer
      分子予防環境医学研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-01-23
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2009

    • Author(s)
      曽和義広, 他
    • Organizer
      分子予防環境医学研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-01-23
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Presentation] ニンニク成分diallyl trisulfide によるROSを介したヒト大腸癌細胞増殖抑制機構の解析2009

    • Author(s)
      曽和義広, 他
    • Organizer
      分子予防環境医学研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-01-23
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] CDK阻害因子p15^<INK4b> 誘導化合物の探索と新規MEK阻害剤としての同定2008

    • Author(s)
      曽和義広, 他
    • Organizer
      がん分子標的治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] CDK阻害因子p15^<INK4b>誘導化合物の探索と新規MEK阻害剤としての同定2008

    • Author(s)
      曽和義広, 他
    • Organizer
      がん分子標的治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Presentation] Identification of p15^<INK4b> -inductive compound, as a novel MEK 1/2 inhibitor2008

    • Author(s)
      Sowa Y., et al.
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] CDK阻害因子p15^<INK4b>誘導化合物の探索と新規MEK阻害剤としての同定2008

    • Author(s)
      曽和義広, 他
    • Organizer
      がん分子標的治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介した癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      がん予防大会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Presentation] ニンニク成分diallyl trisulfide によるROSを介しか癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      がん予防大会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介した癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      日本衛生学会
    • Place of Presentation
      熊本
    • Year and Date
      2008-03-30
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] ニンニク成分diallyl trisulfide によるROSを介したヒト大腸癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      日本フードファクター学会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      日本フードファクター学会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] Identification of p15^<INK4b>-inductive compound, as a novel MEK 1/2 inhibitor2008

    • Author(s)
      Sowa Y., et.al.
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] CDK阻害因子p15INK4b誘導化合物の探索と新規MEK阻害剤としての同定2008

    • Author(s)
      曽和義広, 他
    • Organizer
      がん分子標的治療研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-19659151
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      日本フードファクター学会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介したヒト大腸癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      日本フードファクター学会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-17
    • Data Source
      KAKENHI-PROJECT-19659151
  • [Presentation] Identification of p15^<INK4b> -inductive compound, as a novel MEK 1/2 inhibitor2008

    • Author(s)
      Sowa Y., et al.
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介した癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      がん予防大会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19590593
  • [Presentation] Identification of p15INK4b-inductive compound, as a novel MEK 1/2 inhibitor2008

    • Author(s)
      Sowa Y., et al.
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-28
    • Data Source
      KAKENHI-PROJECT-19659151
  • [Presentation] ニンニク成分diallyl trisulfideによるROSを介した癌細胞増殖抑制機構の解析2008

    • Author(s)
      曽和義広, 他
    • Organizer
      がん予防大会
    • Place of Presentation
      福岡
    • Year and Date
      2008-05-23
    • Data Source
      KAKENHI-PROJECT-19659151
  • [Presentation] Molecular-targeting cancer chemoprevention using p53-RB pathway2007

    • Author(s)
      Sowa Y., et. al.
    • Organizer
      International Symposium on Translational Research
    • Place of Presentation
      Lonavala, Mumbai, India
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-17209022
  • [Presentation] Molecular-targeting cancer chemoprevention using p53-RB pathway2007

    • Author(s)
      SowaY., et. al.
    • Organizer
      International Symposium on Translational Research
    • Place of Presentation
      Lonavala,Mumbai,India
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-18032062
  • [Presentation] Molecular-targeting cancer chemoprevention using p53-RB pathway2007

    • Author(s)
      Sowa Y., et. al.
    • Organizer
      International Symposium on Translational Research
    • Place of Presentation
      Lonavala, Mumbai, India
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-19659151
  • [Presentation] フラボンや分子標的薬によるRB非依存的なG1期停止の誘導

    • Author(s)
      友杉充宏、曽和義広、酒井敏行
    • Organizer
      日本衛生学会学術総会
    • Place of Presentation
      金沢大学鶴間キャンパス
    • Data Source
      KAKENHI-PROJECT-21249042
  • [Presentation] HDAC阻害剤YM753(OBP-801)による食道がん細胞株における放射線と5FUの併用効果の増強

    • Author(s)
      古谷 晃伸, 曽和 義広, 藤原 斉, 小西 博貴, 村山 康利, 小松 周平, 塩崎 敦, 栗生 宜明, 生駒 久視, 窪田 健, 中西 正芳, 市川 大輔, 岡本 和真, 浦田 泰生, 酒井 敏行, 大辻 英吾
    • Organizer
      日本外科学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24591958
  • [Presentation] 新規MEK阻害剤trametinibなどによるRB再活性化により大腸癌細胞株に対する5-FU感受性が増強される

    • Author(s)
      渡邉元樹、曽和義広、酒井敏行
    • Organizer
      日本がん分子標的治療学会学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659305
  • [Presentation] フラボンや分子標的薬によるRB非依存的なG1期停止の誘導

    • Author(s)
      友杉充宏、曽和義広、安田周祐、小山真、酒井敏行
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Data Source
      KAKENHI-PROJECT-21249042
  • [Presentation] 食道がん細胞株に対するHDAC阻害剤OBP-801/YM753と放射線と5-FUの三者併用効果の検討

    • Author(s)
      古谷 晃伸, 曽和 義広, 藤原 斉, 塩崎 敦, 窪田 健, 市川 大輔, 岡本 和真, 浦田 泰生, 酒井 敏行, 大辻 英吾
    • Organizer
      日本食道学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24591958
  • [Presentation] Novel MEK inhibitor trametinib and RB-reactivating agents enhance efficiency of 5-Fluorouracil on human colon cancer cells

    • Author(s)
      Motoki Watanabe, Yoshihiro Sowa, Toshiyuki Sakai
    • Organizer
      日本癌学会学術総会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24659305
  • 1.  SAKAI Toshiyuki (20186993)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 50 results
  • 2.  YOGOSAWA Shingo (70381936)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 18 results
  • 3.  MATSUZAKI Yoichiro (70282522)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 4.  YOSHIDA Tatsushi (80315936)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 5 results
  • 5.  HORINAKA Mano (80512037)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 11 results
  • 6.  KAMIYAMA Jun (20257538)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  高橋 千絵 (90305574)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  加藤 満雄 (70260221)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  NOMURA Hitoshi
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  FUJIWARA Hitoshi (20332950)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 11.  OTSUJI Eigo (20244600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 12.  山岸 久一 (40128723)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  糸井 啓純 (80203123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  窪田 健 (70388180)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  中西 涼子 (60398378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  友杉 充宏 (60533429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 17.  増田 光治 (10305568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  渡邉 元樹 (40723581)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 19.  飯泉 陽介 (20533178)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 20.  石川 秀樹 (30351795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  武藤 倫弘 (30392335)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  FUJII Hideji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  MIZUNO Takakazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  石原 英幹
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  増田 悦子
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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