Yamamoto Takeshi 山本武

… Alternative Names

YAMAMOTO Takeshi 山本武

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Researcher Number	70316181
Other IDs
Affiliation (Current)	2025: 金沢学院大学, 栄養学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 富山大学, 学術研究部薬学・和漢系, 助教 2007 – 2018: University of Toyama, Institute of Natural Medicine, Assistant Professor 2016 – 2017: 富山大学, 和漢薬研究所, 助手 2006: 富山大学, 和漢医薬学総合研究所, 助手 2003: Siebold University of Nagasaki, Dep. Nutrition, instructor, 助手 2002 – 2003: 県立長崎シーボルト大学, 看護栄養学部, 助手
Review Section/Research Field	Principal Investigator General internal medicine(including psychosomatic medicine) / General internal medicine (including Psychosomatic medicine) / Basic Section 52010:General internal medicine-related Except Principal Investigator General internal medicine(including psychosomatic medicine) / Applied pharmacology / Environmental physiology (including Physical medicine and Nutritional physiology) / General internal medicine (including Psychosomatic medicine)
Keywords	Principal Investigator 腸管粘膜免疫 / 葛根湯 / 食物アレルギー / 制御性T細胞 / 腸管粘膜免疫系 / 東洋医学 / 漢方薬 / 経口免疫療法 / レチノイン酸 / プエラリン … More / 樹状細胞 / 制御性細胞 / 粘膜型マスト細胞 / T細胞 / サイトカイン / マイクロアレイ … More Except Principal Investigator CRBPII / 腸管粘膜免疫系 / 東洋医学 / 標的タンパク質 / リポジショニング / 和漢医薬学 / 実験薬理学的検証 / 標的タンパク質探索 / 結合シミュレーション / 機械学習手法 / インシリコ / in silico結合シミュレーション / 機械学習 / 医薬ビッグデータ / 複雑系 / ドラッグ・リポジショニング / 漢方薬 / cytokine / type-2 helper T cell / intestinal mucosal immune system / nicotinic acetylcholine receptor s / oxazolone / ulcerative Colitis / ニコチン受容体 / サイトカイン / Th2 / ニコチン性アセチルコリン受容体 / オキサゾロン / 潰瘍性大腸炎 / thyroid hormone (T3) / rat jejunum / Hydrocorticoid / chick duodenum / β-carotene dioxygenase / coactivator (p300) / PPARS / rat intestine / p300 / CBP / coactivator / PPARδ / PPARα / レチノール吸収 / 発達過程 / CRBP II / 甲状腺ホルモンT3 / ラット空腸 / ハイドロコルチコイド / ニワトリ十二指腸 / βカロテン開裂酵素 / コアクチベータ(p300) / PPARs / CD25 / Foxp3 / 樹状細胞 / 末梢性免疫寛容 / 活性化T細胞 / 制御性T細胞 / 食物アレルギー / 葛根湯 Less

Induction of tolerance by concomitant use of kakkonto with oral immunotherapy and exploration of candidate blood marker that enable evaluation of the effects of treatments for food allergyPrincipal Investigator
- Principal Investigator
  
  Yamamoto Takeshi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  University of Toyama
Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapyPrincipal Investigator
- Principal Investigator
  
  Yamamoto Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama
Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseases
- Principal Investigator
  
  Kadowaki Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama
Anti-allergic effect of kakkonto by regulating intestinal mucosal immunity through the induction of regulatory T cells in the colonPrincipal Investigator
- Principal Investigator
  
  Yamamoto Takeshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama
The effect of kakkonto in allergic immune response mediated by dendritic cells on intestinal mucosal immune systemPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Takeshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
Immunological tolerance induced by Kampo medicine kakkonto through the regulation of helper T cell differentiation in the mucosal immune system of the intestine.
- Principal Investigator
  
  KADOWAKI Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
The therapeutic mechanisms of action of kakkonto in a mouse model of food allergy with gastrointestinal symptoms.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Takeshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  University of Toyama
  Toyama Medical and Pharmaceutical University
Pathophysiological Role of Cholinergic Anti-inflammatory Pathway via Nicotinic Acetylcholine Receptors in Experimental Ulcerative Colitis
- Principal Investigator
  
  KADOWAKI Makoto
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Toyama
Studies of molecular Nutrition on Retinoid absorption and metabolism
- Principal Investigator
  
  TAKASE Sachiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Siebold University of Nagasaki

[Journal Article] Allergic inflammation disrupts epithelial electrogenic electrolyte transport through cholinergic regulation in the mouse colon2023
- Author(s)
  Yamamoto Takeshi, Katsuki Yosuke, Kanauchi Yuya, Hayashi Shusaku, Kadowaki Makoto
- Journal Title
  
  Biomed. Res.
  
  Volume: 44 Issue: 1 Pages: 31-40
- DOI
  10.2220/biomedres.44.31
- ISSN
  0388-6107, 1880-313X
- Year and Date
  2023-01-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-17KK0166, KAKENHI-PROJECT-21K06593
[Journal Article] Neuro-immune crosstalk and food allergy: Focus on enteric neurons and mucosal mast cells2022
- Author(s)
  Kadowaki Makoto, Yamamoto Takeshi, Hayashi Shusaku
- Journal Title
  
  Allergol. Int.
  
  Volume: 71 Issue: 3 Pages: 278-287
- DOI
  10.1016/j.alit.2022.03.004
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Cholinergic anti-inflammatory pathway ameliorates murine experimental Th2-type colitis by suppressing the migration of plasmacytoid dendritic cells2022
- Author(s)
  Kanauchi Yuya、Yamamoto Takeshi、Yoshida Minako、Zhang Yue、Lee Jaemin、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 54-54
- DOI
  10.1038/s41598-021-04154-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098, KAKENHI-PROJECT-21K06593
[Journal Article] Identification of key pathways and gene expression in the activation of mast cells via calcium flux using bioinformatics analysis2021
- Author(s)
  Wang X, Yamamoto T, Kadowaki M, Yang Y
- Journal Title
  
  BIOCELL
  
  Volume: 45 Issue: 2 Pages: 395-415
- DOI
  10.32604/biocell.2021.012280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Pathophysiological Roles of Neuro-Immune Interactions between Enteric Neurons and Mucosal Mast Cells in the Gut of Food Allergy Mice2021
- Author(s)
  Yashiro Tomoe、Ogata Hanako、Zaidi Syed Faisal、Lee Jaemin、Hayashi Shusaku、Yamamoto Takeshi、Kadowaki Makoto
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 7 Pages: 1586-1586
- DOI
  10.3390/cells10071586
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Suppression of plasmacytoid dendritic cell migration to colonic isolated lymphoid follicles abrogates the development of colitis2021
- Author(s)
  Zhang Yue、Yamamoto Takeshi、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 141 Pages: 111881-111881
- DOI
  10.1016/j.biopha.2021.111881
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Isoflavones Suppress Cyp26b1 Expression in the Murine Colonic Lamina Propria2020
- Author(s)
  Yamamoto Takeshi、Nagata Yuka、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 12 Pages: 1945-1949
- DOI
  10.1248/bpb.b20-00355
- NAID
  130007948731
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Ginger Increases ALDH1A1 Expression and Enhances Retinoic Acid Signaling in a Human Colonic Epithelial Cell Line2020
- Author(s)
  Nagata Y, Yamamoto T, Kadowaki M.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 66 Issue: 5 Pages: 462-467
- DOI
  10.3177/jnsv.66.462
- NAID
  130007932347
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2020-10-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] Therapeutic Benefit in Allergic Dermatitis Derived from the Inhibitory Effect of Byakkokaninjinto on the Migration of Plasmacytoid Dendritic Cells2020
- Author(s)
  Yamamoto Takeshi、Zhang Yue、Kigasawa Ai、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Evidence-Based Complementary and Alternative Medicine
  
  Volume: 2020 Issue: 1 Pages: 1-10
- DOI
  10.1155/2020/9532475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06698, KAKENHI-PROJECT-19K07908, KAKENHI-PROJECT-20K07098
[Journal Article] The isoflavone puerarin induces Foxp3+ regulatory T cells by augmenting retinoic acid production, thereby inducing mucosal immune tolerance in a murine food allergy model2019
- Author(s)
  Yamamoto Takeshi、Matsunami Emi、Komori Koji、Hayashi Shusaku、Kadowaki Makoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 516 Issue: 3 Pages: 626-631
- DOI
  10.1016/j.bbrc.2019.06.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07908
[Journal Article] 食物アレルギー病態モデルマウスを用いて新たに見出した葛根湯併用経口免疫療法の根本的治療法としての提案2018
- Author(s)
  山本　武
- Journal Title
  
  LABIO21
  
  Volume: 74 Pages: 17-20
- Data Source
  KAKENHI-PROJECT-16K09234
[Journal Article] Improvement of Therapeutic Efficacy of Oral Immunotherapy in Combination with Regulatory T Cell-Inducer Kakkonto in a Murine Food Allergy Model.2017
- Author(s)
  Nagata Y, Yamamoto T, Hayashi M, Hayashi S, Kadowaki M.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 1 Pages: e0170577-e0170577
- DOI
  10.1371/journal.pone.0170577
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09234, KAKENHI-PROJECT-15K18873, KAKENHI-PROJECT-16H05276
[Journal Article] PI3K p85alpha Subunit-deficient Macrophages Protect Mice from Acute Colitis due to the Enhancement of IL-10 Production.2017
- Author(s)
  Hayashi S., Hamada T., Zinsou D. G. A., Oshiro M., Itoi K., Yamamoto T., Kadowaki M.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 6187-6187
- DOI
  10.1038/s41598-017-06464-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05276, KAKENHI-PROJECT-16K15408, KAKENHI-PROJECT-15K18873
[Journal Article] Induction of regulatory T cells as a novel mechanism underlying the therapeutic action of kakkonto, a traditional Japanese herbal medicine, in a murine food allergy model2016
- Author(s)
  Yamamoto T, Fujiwara K, Tsubota Y, Kageyama-Yahara N, Hayashi S, Kadowaki M
- Journal Title
  
  International Archives of Allergy and Immunology
  
  Volume: 169 Issue: 3 Pages: 146-156
- DOI
  10.1159/000445433
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460891, KAKENHI-PROJECT-16H05276
[Journal Article] Anti-allergic role of cholinergic neuronal pathway via α7 nicotinic ACh receptors on mucosal mast cells in a murine food allergy model2014
- Author(s)
  Yamamoto T., Kodama T., Lee J., Utsunomiya N., Hayashi S., Sakamoto H., Kuramoto H., Kadowaki M.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: 85888-85888
- DOI
  10.1371/journal.pone.0085888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PROJECT-24790657, KAKENHI-PROJECT-25460891
[Journal Article] Shikonin, a constituent of Lithospermum erythrorhizon exhibits anti-allergic effects by suppressing orphan nuclear receptor Nr4a family gene expression as a new prototype of calcineurin inhibitors in mast cells2014
- Author(s)
  Wang X., Hayashi S., Umezaki M., Yamamoto T., Kageyama-Yahara N., Kondo T., Kadowaki M.
- Journal Title
  
  Chemico-Biological Interactions
  
  Volume: 224 Pages: 117-127
- DOI
  10.1016/j.cbi.2014.10.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PROJECT-25460891
[Journal Article] <b>CGRP, a neurotransmitter of enteric sensory neurons, contributes to the development of food allergy due to the augmentation of microtubule reorganization in mucosal mast </b><b>cells </b>2014
- Author(s)
  Kim JH., Yamamoto T., Lee J., Yashiro T., Hamada T., Hayashi S., Kadowaki M.
- Journal Title
  
  Biomed. Res.
  
  Volume: 35 Issue: 4 Pages: 285-293
- DOI
  10.2220/biomedres.35.285
- NAID
  130004678584
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460891
[Journal Article] 食物アレルギーに対する漢方薬治療を目指した病態モデルを用いた基礎的検討2014
- Author(s)
  山本武, 門脇真
- Journal Title
  
  アレルギーの臨床
  
  Volume: 8月号 Pages: 643-646
- Data Source
  KAKENHI-PROJECT-25460891
[Journal Article] TRPM2 contributes to antigen-stimulated Ca2+ influx in mucosal mast cells2013
- Author(s)
  Oda S., Uchida K., Wang X., Lee J., Shimada Y., Tominaga M., Kadowaki M.
- Journal Title
  
  Pflugers Archiv : European journal of physiology
  
  Volume: 465 Issue: 3 Pages: 895-900
- DOI
  10.1016/j.bbrc.2012.12.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PROJECT-24790657, KAKENHI-PROJECT-25460891
[Journal Article] Oral Tolerance Induced by Transfer of Food Antigens via Breast Milk of Allergic Mothers Prevents Offspring from Developing Allergic Symptoms in a Mouse Food Allergy Model2012
- Author(s)
  Yamamoto T, Tsubota Y, Kodama T, Kageyama-Yahara N, Kadowaki M
- Journal Title
  
  Clinical and Developmental Immunology Volume 2012(2012)
  
  Volume: 2012 Pages: 721085-721085
- DOI
  10.1155/2012/721085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760, KAKENHI-PROJECT-22790616
[Journal Article] Sphingosine kinase-1-dependent and -independent inhibitory effects of zanthoxyli fructus to attenuate the activation of mucosal mast cells and ameliorate food allergies in mice2012
- Author(s)
  Wang X, Kageyama-Yahara N, Hayashi S, Yamamoto T, Kadowaki M.
- Journal Title
  
  Evid Based Complement Alternat Med
  
  Volume: 2012 Pages: 862743-862743
- DOI
  10.1155/2012/862743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790616, KAKENHI-PROJECT-24406005, KAKENHI-PROJECT-24590879, KAKENHI-PROJECT-24790657
[Journal Article] Rab5a Regulates Surface Expression of Fc.EPSILON.RI and Functional Activation in Mast Cells2011
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Yamamoto T, Kadowaki M
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 34 Issue: 5 Pages: 760-763
- DOI
  10.1248/bpb.34.760
- NAID
  130000657792
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760, KAKENHI-PROJECT-22790616
[Journal Article] Rab5a regulates surface expression of FcεRI and functional activation in mast cells2011
- Author(s)
  Kageyama-Yahara N., Suehiro Y., Yamamoto T., Kadowaki M
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 34 Pages: 760-763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Suppression of phospholipase Cγ1 phosphorylation by cinnamaldehyde inhibits antigen-induced extracellular calcium influx and degranulation in mucosal mast cells2011
- Author(s)
  Kageyama-Yahara N., Wang X., Katagiri T., Wang P., Yamamoto T., Tominaga M., Kadowaki M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 416 Pages: 283-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Suppression of phospholipase Cγ1 phosphorylation by cinnamaldehyde in hibits antigen-induced extracellular calcium influx and degranulation in mucosal mast cells2011
- Author(s)
  Kageyama-Yahara N, Wang X, Katagiri T, Wang P, Yamamoto T, Tominaga M, Kadowaki M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 416 Issue: 3-4 Pages: 283-8
- DOI
  10.1016/j.bbrc.2011.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760, KAKENHI-PROJECT-22790616
[Journal Article] The inhibitory effect of ergosterol, a bioactive constituent of a traditional Japanese herbal medicine saireito on the activity of mucosal-type mast cells.2010
- Author(s)
  Kageyama-Yahara N., Wang P., Wang X., Yamamoto T., Kadowaki M.
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 33 Pages: 142-145
- NAID
  130000140209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Pentagalloylglucose down-regulates mast cell surface FcepsilonRl expres sion in vitro and in vivo.2010
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Maeda F, Kageyama S, Fukuoka J, Katagiri T, Yamamoto T, Kadowaki M.
- Journal Title
  
  FEBS Lett. 584
  
  Pages: 111-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790472
[Journal Article] Pentagalloy lglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo2010
- Author(s)
  Kageyama-Yahara N., Suehiro Y., Maeda F., Kageyama S., Fukuoka J., Katagiri T., Yamamoto T., Kadowaki M
- Journal Title
  
  FEBS Letter
  
  Volume: 584 Pages: 111-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo.2010
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Maeda F, Kageyama S, Fukuoka J, Katagiri T, Yamamoto T, Kadowaki M.
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 111-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790616
[Journal Article] The inhibitory effect of ergosterol, a bioactive constituent of a traditional Japanese herbal medicine saireito on the activity of mucosal-type mast cells2010
- Author(s)
  Kageyama-Yahara N., Wang P., Wang X., Yamamoto T., Kadowaki M
- Journal Title
  
  Biological & Pharmaceutical Bulletin
  
  Volume: 33 Pages: 142-145
- NAID
  130000140209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] The inhibitory effect of ergosterol, a bioactive constituent of a traditional Japanese herbal medicine Saireito on the activity of mucosal-type mast cells.2010
- Author(s)
  Kageyama-Yahara N, Wang P, Wang X, Yamamoto T, Kadowaki M.
- Journal Title
  
  Biol. Pharm. Bull. 33
  
  Pages: 142-5
- NAID
  130000140209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790472
[Journal Article] The Inhibitory Effect of Ergosterol, a Bioactive Constituent of a Traditional Japanese Herbal Medicine Saireito on the Activity of Mucosal-Type Mast Cells2010
- Author(s)
  Kageyama-Yahara N, Wang P, Wang X, Yamamoto T, Kadowaki M.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 33 Issue: 1 Pages: 142-145
- DOI
  10.1248/bpb.33.142
- NAID
  130000140209
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790616
[Journal Article] Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo.2010
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Maeda F, Kageyama S, Fukuoka J, Katagiri T, Yamamoto T, Kadowaki M.
- Journal Title
  
  FEBS Lett.
  
  Volume: 584 Pages: 111-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo.2010
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Maeda F, Kageyama S, Fukuoka J, Katagiri T, Yamamoto T, Kadowaki M.
- Journal Title
  
  FEBS Lett 584
  
  Pages: 111-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790472
[Journal Article] Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo2010
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Maeda F, Kageyama S, Fukuoka J, Katagiri T, Yamamoto T, Kadowaki M.
- Journal Title
  
  FEBS Lett.
  
  Volume: 4 Issue: 1 Pages: 111-118
- DOI
  10.1016/j.febslet.2009.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790616
[Journal Article] Pentagalloylglucose down-regulates mast cell surface FcepsilonRI expression in vitro and in vivo.2010
- Author(s)
  Kageyama-Yahara N, Suehiro Y, Maeda F, Kageyama S, Fukuoka J, Katagiri T, Yamamoto T, Kadowaki M.
- Journal Title
  
  FEBS Lett. 584
  
  Pages: 111-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590760
[Journal Article] Therapeutic Effect of Kakkonto in a Mouse Model of Food Allergy withGastrointestinal Symptoms2009
- Author(s)
  Takeshi Yamamoto
- Journal Title
  
  International Archives of Allergy and Immunology 148
  
  Pages: 175-185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790472
[Journal Article] The Traditional Herbal Medicine Saireito Exerts Its Inhibitory Effect on Murine Oxazolone-Induced Colitis via the Induction of Th1-Polarized Immune Responses in the Mucosal Immune System of the Colon.2009
- Author(s)
  Watanabe T, Yamamoto T, Yoshida M, Fujiwara K, Kageyama-Yahara N, Kuramoto H, Shimada Y, Kadowaki M.
- Journal Title
  
  Int Arch Allergy Immunol 151
  
  Pages: 98-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790472
[Journal Article] Therapeutic effect of kakkonto in a mouse model of food allergy with gastrointestinal symptoms.2009
- Author(s)
  Yamamoto T, Fujiwara K, Yoshida M, Kageyama-Yahara N, Kuramoto H, Shibahara N, Kadowaki M.
- Journal Title
  
  Int Arch Allergy Immunol 148
  
  Pages: 175-185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790472
[Journal Article] Alteration of cholinergic, purinergic and sensory neurotransmission in the mouse colon of food allergy model.2008
- Author(s)
  Leng Y, Yamamoto T, Kadowaki M.
- Journal Title
  
  Neurosci Lett 445
  
  Pages: 195-198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790472
[Journal Article] Downregulation in aquaporin 4 and aquaporin 8 expression of the colon associated with the induction of allergic diarrhea in a mouse model of food allergy2007
- Author(s)
  Yamamoto, T
- Journal Title
  
  Life Sciences 81
  
  Pages: 115-120
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Journal Article] Downregulation in aquaporin 4 and aquaporin 8 expression of the colon associated with the induction of allergic diarrhea in a mouse model of food allergy.2007
- Author(s)
  Yamamoto T
- Journal Title
  
  Life Sciences 81
  
  Pages: 115-120
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590507
[Journal Article] Downregulation in aquaporin 4 and aquaporin 8 expression of the colonassociated with the induction of allergic diarrhea in a mouse model of food allergy2007
- Author(s)
  Yamamoto T
- Journal Title
  
  Life Sciences 81
  
  Pages: 115-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590507
[Journal Article] Therapeutic effect of kakkonto on food allergy model mice with gastrointestinal symptoms
- Author(s)
  Yamamoto, T
- Journal Title
  
  International Archives of Allergy and Immunology(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Journal Article] Therapeutic effect of kakkonto on food allergy model mice with gastrointestinal symptoms
- Author(s)
  Yamamoto T
- Journal Title
  
  International Archives of Allergy and Immunology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] GPR41-positive enteric sensory neurons are in close proximity to intestinal macrophages in the colonic mucosa of murine colitis model.2022
- Author(s)
  Hayashi Shusaku, Hertati Ai, Yamamoto Takeshi, Kadowaki Makoto.
- Organizer
  Cell Symposia: The Neuro-Immune Axis; Lisbon.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] 芳香族炭化水素受容体活性化の食物アレルギーへの効果と制御性T細胞の誘導の病態マウスを用いた検討．2022
- Author(s)
  山本武，後藤由佳，門脇真
- Organizer
  第71回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] Neurogenesis and neurodegeneration in enteric neurons of DSS colitis mouse colon.2022
- Author(s)
  Miyata Kana, Ogata Hanako, Yamamoto Takeshi, Hayashi Shusaku, Kadowaki Makoto.
- Organizer
  Cell Symposia: The Neuro-Immune Axis; Lisbon.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] 病態モデルマウスを用いたAhRアゴニストによる食物アレルギーの治療効果の検討2022
- Author(s)
  山本武，後藤由佳，門脇真．
- Organizer
  第39回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] 食物アレルギー病態マウスを用いた長期葛根湯併用による経口免疫療法の寛解維持効果向上の検討.2021
- Author(s)
  山本武, 後藤由佳, 門脇真.
- Organizer
  第70回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] 葛根湯併用経口免疫療法による食物アレルギー治療の粘膜型マスト細胞脱顆粒抑制作用とその機序の検討.2021
- Author(s)
  山本武, 後藤由佳, 門脇真.
- Organizer
  第38回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] 葛根湯併用経口免疫療法による食物アレルギー疾患の寛解維持誘導について病態マウスを用いた検討．2020
- Author(s)
  山本武，宋夢テイ，後藤由佳，門脇真．
- Organizer
  第37回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] 食物アレルギー病態マウスを用いた葛根湯と経口免疫療法の併用療法による寛解維持効果の検討．2020
- Author(s)
  山本武，宋夢テイ，後藤由佳，門脇真．
- Organizer
  JSA/WAO Joint Congress 2020 (第69回日本アレルギー学会学術大会)
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] An evaluation of the effects of Kakkonto in combination with dietary advice in children with food allergies through a non-randomized controlled trial.2020
- Author(s)
  Kato T., Ito Y., Yamamoto T., Shimizu M., Itazawa T., Adachi Y., Kadowaki M., Adachi Y.
- Organizer
  JSA/WAO Joint Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] 葛根湯と経口免疫療法の併用療法による粘膜型マスト細胞の活性化抑制を介した脱感作誘導率の向上2019
- Author(s)
  山本武, 林美智慧, 長田夕佳, 門脇真
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] Induction of desensitization by combined therapy with oral immunotherapy and kakkonto in food allergy.2019
- Author(s)
  Song M., Yamamoto T., Nagata Y., Kadowaki M.
- Organizer
  第36回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] AhR agonist combined with oral immunotherapy can alleviate food allergy by induction of CD4+Foxp3+ regulatory T cells in the colon of food allergy model mice.2019
- Author(s)
  Yamamoto T., Gou Q., Kadowaki M.
- Organizer
  19th International Congress of Mucosal Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07908
[Presentation] Therapeutic effects of inhibitors of the migration of plasmacytoid dendritic cells, but not conventional dendritic cells in a murine colitis model.2018
- Author(s)
  Zhang Y., Yamamoto T., Kadowaki M.
- Organizer
  Digestive Disease Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] マウス食物アレルギー病態モデルを用いて新たに見出した葛根湯併用経口免疫療法の根本的治療法としての提案2018
- Author(s)
  山本武
- Organizer
  第65回日本実験動物学会, シンポジウム, 2018, 5, 16-18, 富山
- Invited
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] Therapeutic effect and preventive effect of kakkonto on food allergy.2018
- Author(s)
  Yamamoto T
- Organizer
  2018 CAP Sikchi symposium, The Relationship between Medicinal Food and Nutrition in Health Care, 2018, 9, 6-7, Jeju, Korea.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 葛根湯の制御性T細胞誘導作用を活用した食物アレルギーの新規治療法の開発研究2018
- Author(s)
  山本武
- Organizer
  第35回和漢医薬学会学術大会, 学術貢献賞受賞講演, 2018, 9, 1-2, 岐阜.
- Invited
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 経口免疫療法モデルマウスを用いた葛根湯併用療法の寛解維持効果の検討2018
- Author(s)
  長田夕佳, 山本武, 門脇真
- Organizer
  第67回日本アレルギー学会学術大会, 2018, 6, 22-24, 千葉.
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] Long-Term Effect of Combined Therapy of Oral Immunotherapy and Japanese Traditional Medicine Kakkonto on Food Allergy Mice.2018
- Author(s)
  Nagata Y., Yamamoto T., Kadowaki M.
- Organizer
  American Academy of Allergy Asthma & Immunology (AAAAI) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 葛根湯併用経口免疫療法による食物アレルギー治療の寛解維持効果についてモデルマウスを用いた検討2018
- Author(s)
  山本武, 長田夕佳, 門脇真
- Organizer
  第35回和漢医薬学会学術大会, 2018, 9, 1-2, 岐阜.
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 制御性T細胞誘導薬を経口免疫療法に併用した食物アレルギーの新たな治療法の開発.2018
- Author(s)
  山本武
- Organizer
  日本薬学会北陸支部第130回例会,若手シンポジウム, 2018, 11, 18, 富山.
- Invited
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 『食物アレルギーの治療法の確立への葛根湯の応用』- 葛根湯による腸管粘膜免疫系の制御作用を介した効果-2017
- Author(s)
  山本武
- Organizer
  天然薬物研究方法論アカデミー第20回研究集会.
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] Intestinal Regulatory T Cells Induced by Kakkonto, a Traditional Japanese Herbal Medicine, Improve Therapeutic Efficacy of Oral Immunotherapy in Food Allergy Model Mice.2017
- Author(s)
  Yamamoto T., Nagata Y., Hayashi M., Kadowaki M.
- Organizer
  18th International Congress of Mucosal Immunology (ICMI 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 経口免疫療法と葛根湯の併用療法による食物アレルギーの治療効果増加の機序の検討.2017
- Author(s)
  山本武, 長田夕佳, 林美智慧, 苟巧, 門脇真
- Organizer
  第34回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] Improvement of Therapeutic Efficacy of Oral Immunotherapy in Combination with Regulatory T Cell-inducer Kakkonto in a Murine Food Allergy Model.2017
- Author(s)
  Kadowaki M., Nagata Y., Hayashi M., Hayashi S., Yamamoto T
- Organizer
  East-West Integrative Medicine for Immunology & Wellness
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] 食物アレルギー病態モデルに対する葛根湯と経口免疫療法の併用療法によるレチノイン酸代謝酵素抑制を介した制御性T細胞の誘導.2017
- Author(s)
  長田夕佳, 山本武, 門脇真
- Organizer
  第66回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] Intestinal Regulatory T Cells Induced by Kakkonto, a Traditional Japanese Herbal Medicine, Improve Therapeutic Efficacy of Oral Immunotherapy in Food Allergy Model Mice.2017
- Author(s)
  Yamamoto T., Nagata Y., Hayashi M., Kadowaki M
- Organizer
  International Congress of Mucosal Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05276
[Presentation] 葛根湯と経口免疫療法の併用療法モデルによるレチノイン酸代謝酵素抑制を介した制御性T細胞の誘導.2016
- Author(s)
  長田夕佳, 山本武, 門脇真.
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 腸管制御性T細胞誘導能を持つ葛根湯と経口免疫療法の併用療法は食物アレルギー病態モデルでの治療効果を亢進させる.2016
- Author(s)
  長田夕佳, 山本武, 林美智慧, 門脇真.
- Organizer
  日本薬学会北陸支部第128回例会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 経口免疫療法による食物アレルギーの治療における葛根湯の併用効果のモデルマウスを用いた検討.2016
- Author(s)
  山本武, 長田夕佳, 林美智慧, 門脇真.
- Organizer
  第33回和漢医薬学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 葛根湯の主成分プエラリンのレチノイン酸依存的な制御性T細胞の誘導による食物アレルギーに対する治療効果.2015
- Author(s)
  山本武, 松並恵未, 小森宏次, 門脇真
- Organizer
  第32回和漢医薬学会学術大会
- Place of Presentation
  富山
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] ダイオキシン受容体の活性化は制御性T細胞の誘導を介して食物アレルギーの発症を抑制する.2015
- Author(s)
  小森宏次, 山本武, 門脇真
- Organizer
  日本薬学会北陸支部第127回例会
- Place of Presentation
  富山
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] 葛根湯の主成分プエラリンのレチノイン酸依存的制御性T細胞誘導による食物アレルギーモデルでの治療効果.2015
- Author(s)
  山本武, 松並恵未, 小森宏次, 門脇真
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  東京
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] 食物アレルギーの病態形成における腸管神経の病態生理学的役割.2015
- Author(s)
  門脇真, 李在敏, 八代智江, 緒方華子, 金志ギャン, 山本武
- Organizer
  生体機能と創薬シンポジウム
- Place of Presentation
  船橋
- Year and Date
  2015-08-27
- Invited
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] ダイオキシン受容体は食物アレルギーの創薬標的になりうるのか.2015
- Author(s)
  小森宏次, 山本武, 門脇真
- Organizer
  フォーラム富山「創薬」第41回研究会
- Place of Presentation
  富山
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] 葛根湯の制御性T細胞の誘導による食物アレルギーモデルでの治療効果.2015
- Author(s)
  山本武, 松並恵未, 小森宏次, 門脇真
- Organizer
  第36回富山免疫アレルギー研究会,
- Place of Presentation
  富山
- Year and Date
  2015-06-25
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] Augmentation of retinoic acid production in the colonic epithelial cells ameliorates food allergy via the induction of foxp3+ regulatory T cells in a murine model.2015
- Author(s)
  Yamamoto T., Matsunami E., Komori K., Kadowaki M.
- Organizer
  17th International Congress of Mucosal Immunology (ICMI2015)
- Place of Presentation
  Berlin
- Year and Date
  2015-07-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] 葛根の主成分puerarinは腸管に制御性T細胞を誘導して食物アレルギー病態モデルで有効性を示す.2014
- Author(s)
  松並恵未, 山本武, 小森宏次, 門脇真
- Organizer
  日本薬学会北陸支部第126回例会
- Place of Presentation
  金沢
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] 葛根湯成分プエラリンによる食物アレルギー抑制機序の検討2013
- Author(s)
  山本武，小森宏次，数馬恒平，門脇真
- Organizer
  第30回和漢医薬学会学術大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] CGRP enhances calcium ionophore-induced degranulation of mucosal-type murine bone marrow-derived mast cells.2013
- Author(s)
  金志玄，李在敏，山本武，門脇真
- Organizer
  日本薬学会北陸支部第 125 回例会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] 食物アレルギー病態モデルにおける制御性T細胞の誘導によるプエラリンの治療効果2013
- Author(s)
  小森宏次，山本武，門脇真
- Organizer
  日本薬学会北陸支部第 125 回例会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] Induction of Foxp3+CD4+ Regulatory T Cells as a Novel Mechanism Underlying the Therapeutic Action of Kakkonto, a Traditional Japanese Herbal Medicine, in a Murine Food Allergy Model．2013
- Author(s)
  Yamamoto T., Kadowaki M.
- Organizer
  16th International Congress of Mucosal Immunology,
- Place of Presentation
  Vancouver, Canada.
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] Kadowaki M. Shikonin suppresses the activation of mucosal mast cells through the inhibition of nuclear orphan receptors NR4A expression.2012
- Author(s)
  Hayashi S., Wang X., Umezaki M., Yamamoto T.
- Organizer
  5th International Symposium on Scientific Research of Traditional Medicine
- Place of Presentation
  富山
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 葛根湯の粘膜免疫系での制御性T細胞誘導による食物アレルギー抑制作用.2012
- Author(s)
  門脇真，山本武
- Organizer
  第16回日本統合医療学会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 葛根成分および代謝物による食物アレルギー性消化器症状の治療効果2012
- Author(s)
  山本武, 門脇真
- Organizer
  第29回和漢医薬学会学術大会.
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] Shikonin suppresses the activation of mucosal mast cells through the inhibition of nuclear orphan receptors NR4A expression.2012
- Author(s)
  Hayashi S., Wang X., Umezaki M., Yamamoto T., Kadowaki M.
- Organizer
  5th International Symposium on Scientific Research of Traditional Medicine
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 葛根湯の粘膜免疫系での制御性T細胞誘導による食物アレルギー抑制作用.2012
- Author(s)
  門脇真, 山本武
- Organizer
  第16回日本統合医療学会(招待講演)
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 紫雲膏の主要活性成分シコニンの核内オーファン受容体NR4Aの遺伝子発現抑制を介したマスト細胞に対する作用2012
- Author(s)
  王暁宇, 林周作, 山本武, 門脇真
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 葛根成分および代謝物による食物アレルギー性消化器症状の治療効果.2012
- Author(s)
  山本武，門脇真
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 紫雲膏の主要活性成分シコニンの核内オーファン受容体NR4Aの遺伝子発現抑制を介したマスト細胞に対する作用.2012
- Author(s)
  王暁宇，林周作，山本武，門脇真
- Organizer
  第29回和漢医薬学会学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 樹状細胞を介した葛根湯によるエフェクターT細胞の分化・増殖の抑制2011
- Author(s)
  山本武,原優加,門脇真
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] 樹状細胞を介した葛根湯によるエフェクターT細胞の分化・増殖の抑制2011
- Author(s)
  山本武, 原優加, 門脇真
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 樹状細胞を介した葛根湯によるエフェクターT細胞の分化・増殖の抑制2011
- Author(s)
  山本武
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山県民会館
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] 樹状細胞を介した葛根湯によるエフェクターT細胞の分化・増殖の抑制2011
- Author(s)
  山本武
- Organizer
  第28回和漢医薬学会学術大会
- Place of Presentation
  富山県民会館(富山県)
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 食物アレルギー病態モデルにおける葛根湯の新規制御性T細胞を介した腸管粘膜免疫抑制作用2010
- Author(s)
  山本武
- Organizer
  第27回和漢医薬学会
- Place of Presentation
  京都薬科大学
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] 食物アレルギー病態モデルにおける葛根湯の新規制御性T細胞を介した腸管粘膜免疫抑制作用2010
- Author(s)
  山本武,藤原加苗,坪田悠真,門脇真
- Organizer
  第27回和漢医薬学会学術大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] 食物アレルギー病態モデルにおける葛根湯の新規制御性T細胞を介した腸管粘膜免疫抑制作用2010
- Author(s)
  山本武, 藤原加苗, 坪田悠真, 門脇真
- Organizer
  第27回和漢医薬学会学術大会.
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] 食物アレルギー病態モデルにおける葛根湯の新規制御性T細胞を介した腸管粘膜免疫抑制作用2010
- Author(s)
  山本武
- Organizer
  第27回和漢医薬学会学術大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790616
[Presentation] Effect of kakkonto, a traditional Japanese herbal medicine, on the differentiation of CD4+T cells in the colon of food allergy model mouse2009
- Author(s)
  Yamamoto T., Fujiwara K., Yoshida M., Kadowaki M
- Organizer
  International Congress of Mucosal Immunology
- Place of Presentation
  Boston, U. S. A.
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] Effect of kakkonto, a traditional Japanese herbal medicine, on the differentiation of CD4+ T cells in the colon of food allergy model mouse.2009
- Author(s)
  Yamamoto T., Fujiwara K., Yoshida M., Kadowaki M.
- Organizer
  International Congress of Mucosal Immunology
- Place of Presentation
  Boston, U.S.A.
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] 食物アレルギー性消化器症状誘発病態モデルにおける葛根湯による制御性T細胞への分化亢進を介する腸管粘膜免疫系の制御機構2009
- Author(s)
  山本武
- Organizer
  第26回和漢医薬学会
- Place of Presentation
  幕張メッセ
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] 食物アレルギー性消化器症状誘発病態モデルにおける葛根湯による制御性T細胞への分化亢進を介する腸管粘膜免疫系の制御機構.2009
- Author(s)
  山本武, 藤原加苗, 氣賀澤愛, 吉田益奈子, 門脇真
- Organizer
  第26回和漢医薬学会学術大会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] 食物アレルギー性消化器症状誘発病態モデルにおける葛根湯による制御性T細胞への分化亢進を介する腸管粘膜免疫系の制御機構(プレナリーセッション講演)2009
- Author(s)
  山本武,藤原加苗,氣賀澤愛,吉田益奈子,門脇真
- Organizer
  第26回和漢医薬学会学術大会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] 食物アレルギー性消化器症状誘発病態モデルにおける葛根湯による制御性T細胞への分化亢進を介する腸管粘膜免疫系の制御機構2009
- Author(s)
  山本武
- Organizer
  第26回和漢医薬学会
- Place of Presentation
  幕張メッセ
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-21590760
[Presentation] 食物アレルギーモデルマウスにおける葛根湯の全身免疫系および腸管粘膜免疫系に対する免疫調節作用.2008
- Author(s)
  山本武, 吉田益奈子, 藤原加苗, 柴原直利, 門脇真
- Organizer
  第25回和漢医薬学会学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] 食物アレルギー性消化器症状誘発モデルにおける葛根湯の有効性とその免疫学的作用機序.2008
- Author(s)
  藤原加苗, 山本武, 吉田益奈子, 柴原直利, 門脇真
- Organizer
  日本薬学会北陸支部第119回例会
- Place of Presentation
  金沢
- Year and Date
  2008-11-09
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] 消化器症状を誘発する食物アレルギーモデルマウスにおける葛根湯の治療効果とその有効生薬.2008
- Author(s)
  藤原加苗, 山本武, 柴原直利, 門脇真
- Organizer
  第25回和漢医薬学会学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] 消化器症状を誘発する食物アレルギーモデルマウスにおける葛根湯の治療効果とその有効生薬2008
- Author(s)
  山本武
- Organizer
  第25回和漢医薬学会学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] 食物アレルギー性消化器症状誘発モデルにおける葛根湯の有効性とその免疫学的作用機序2008
- Author(s)
  山本武
- Organizer
  日本薬学会北陸支部第119回例会
- Place of Presentation
  金沢
- Year and Date
  2008-11-09
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] マウス食物アレルギーモデルマウスにおける葛根湯の全身免疫系および腸管粘膜免疫系に対する免疫調節作用2008
- Author(s)
  山本武
- Organizer
  第25回和漢医薬学会学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20790472
[Presentation] Stimulation of Vagus Nerve Attenuates Inflammation by Activating alpha7 Nicotinic Acetylcholine Receptors in the Colon of Oxazolone-Induced Ulcerative Colitis Mouse.2007
- Author(s)
  Yamamoto T.
- Organizer
  International Congress of Mucosal Immunology.
- Place of Presentation
  Tokyo
- Year and Date
  2007-07-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] Stimulation of Vagus Nerve Attenuates Inflammation by Activating alpha7 Nicotinic Acetylcholine Receptors in the Colon of Oxazolone-Induced Ulcerative Colitis Mouse2007
- Author(s)
  Yamamoto T.
- Organizer
  International Congress of Mucosal Immunology.
- Place of Presentation
  京都
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] Stimulation of Vagus Nerve Attenuates Inflammation by Activating alpha7 Nicotinic Acetylcholine Receptors in the Colon of Oxazolone-Induced Ulcerative Colitis Mouse2007
- Author(s)
  Yamamoto, T
- Organizer
  International Congress of Mucosal Immunology
- Place of Presentation
  Tokyo
- Year and Date
  2007-07-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] PATHOPHYSIOLOGICAL ROLE OF THE CHOLINERGIC ANTI-INFLAMMATORY AND IMMUNE PATHWAY IN MOUSE OXAZOLONE-INDUCED ULCERATIVE COLITIS MODEL.2006
- Author(s)
  Yamamoto T
- Organizer
  Digestive Disease Week
- Place of Presentation
  Los Angeles, U. S. A.
- Year and Date
  2006-05-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] PATHOPHYSIOLOGICAL ROLE OF THE CHOLINERGIC ANTI-INFLAMMATORY AND IMMUNE PATHWAY IN MOUSE OXAZOLONE-INDUCED ULCERATIVE COLITIS MODEL2006
- Author(s)
  Yamamoto, T
- Organizer
  Digestive Disease Week
- Place of Presentation
  Los Angeles, U. S. A.
- Year and Date
  2006-05-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590507
[Presentation] ダイオキシン受容体アゴニストは食物アレルギー病態モデルで治療効果を発揮する.
- Author(s)
  山本武, 小森宏次, 松並恵未, 門脇真
- Organizer
  第26回日本アレルギー学会春季臨床大会
- Place of Presentation
  京都
- Year and Date
  2014-05-09 – 2014-05-11
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] CGRP can enhance activation of mucosal mast cells by augmenting microtubule organization.
- Author(s)
  Kim JH., Yamamoto T., Kadowaki M.
- Organizer
  第26回日本アレルギー学会春季臨床大会
- Place of Presentation
  京都
- Year and Date
  2014-05-09 – 2014-05-11
- Data Source
  KAKENHI-PROJECT-25460891
[Presentation] 葛根湯成分プエラリンによる食物アレルギー抑制機序の検討.
- Author(s)
  山本武, 小森宏次, 松並恵未, 門脇真
- Organizer
  第31回和漢医薬学会学術大会
- Place of Presentation
  千葉
- Year and Date
  2014-08-30 – 2014-08-31
- Data Source
  KAKENHI-PROJECT-25460891

1. KADOWAKI Makoto (20305709)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
2. KAGEYAMA Natsuko (90342865)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HAYASHI SHUUSAKU (10548217)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. TAKASE Sachiko (10046196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. GODA Tohinao (70195923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIDOJI Yoshihiro (00111518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KURAMOTO Hirofumi (30153373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUGIYAMA Toshito (00196768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KADOWAKI Takashi (30185889)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Nagata Yuka (80802016)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
11. 柴原直利 (10272907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 東田千尋 (10272931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山西芳裕 (60437267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 梅嵜雅人 (80534370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Ito Yasunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 矢原夏子

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results

Yamamoto Takeshi 山本 武

YAMAMOTO Takeshi 山本 武

Research Projects

Research Products

Co-Researchers

Induction of tolerance by concomitant use of kakkonto with oral immunotherapy and exploration of candidate blood marker that enable evaluation of the effects of treatments for food allergyPrincipal Investigator

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Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapyPrincipal Investigator

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Mode-of-action analysis of Kampo formulae and prediction of their new indications for a wide range of diseases

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Anti-allergic effect of kakkonto by regulating intestinal mucosal immunity through the induction of regulatory T cells in the colonPrincipal Investigator

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The effect of kakkonto in allergic immune response mediated by dendritic cells on intestinal mucosal immune systemPrincipal Investigator

Principal Investigator

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Immunological tolerance induced by Kampo medicine kakkonto through the regulation of helper T cell differentiation in the mucosal immune system of the intestine.

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The therapeutic mechanisms of action of kakkonto in a mouse model of food allergy with gastrointestinal symptoms.Principal Investigator

Principal Investigator

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Pathophysiological Role of Cholinergic Anti-inflammatory Pathway via Nicotinic Acetylcholine Receptors in Experimental Ulcerative Colitis

Principal Investigator

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Studies of molecular Nutrition on Retinoid absorption and metabolism

Principal Investigator

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Research Institution

[Journal Article] Allergic inflammation disrupts epithelial electrogenic electrolyte transport through cholinergic regulation in the mouse colon2023

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[Journal Article] Neuro-immune crosstalk and food allergy: Focus on enteric neurons and mucosal mast cells2022

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[Journal Article] Cholinergic anti-inflammatory pathway ameliorates murine experimental Th2-type colitis by suppressing the migration of plasmacytoid dendritic cells2022

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[Journal Article] Identification of key pathways and gene expression in the activation of mast cells via calcium flux using bioinformatics analysis2021

Yamamoto Takeshi 山本武

YAMAMOTO Takeshi 山本武

[Journal Article] Induction of regulatory T cells as a novel mechanism underlying the therapeutic action of kakkonto, a traditional Japanese herbal medicine, in a murine food allergy model2016