• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

NAKAHIGASHI Kenji  中東 憲治

ORCIDConnect your ORCID iD *help
Researcher Number 70322740
Other IDs
Affiliation (based on the past Project Information) *help 2015: 慶應義塾大学, 先端生命研, 准教授
2014: 慶應義塾大学, 政策・メディア研究科, 特任准教授
2013 – 2014: 慶應義塾大学, その他の研究科, 准教授
2013: 慶應義塾大学, 政策・メディア研究科, 特任准教授
2012: 慶應義塾大学, 政策・メディア研究科, 特任准教授 … More
2009 – 2010: Keio University, 政策・メディア研究科, 准教授
2008: Keio University, 大学院・政策・メディア研究科, 准教授
2000: Dept.of Biophys., Gard.Sch.Sci.Kyoto Univ.(Assistant Professor), 大学院・理学研究科, 助手 Less
Review Section/Research Field
Principal Investigator
System genome science / 基礎ゲノム科学
Except Principal Investigator
Molecular biology / System genome science / Bioinformatics/Life informatics
Keywords
Principal Investigator
翻訳 / 抗生物質 / コドン / 翻訳制御 / リボソーム / ゲノム解析技術 / リボソームプロファイリング / マルチオミクス / 分子遺伝学 / タンパク質代謝 … More / 大腸菌 / プロテオミクス / 翻訳郊率 / タンパク質分解 / タンパク質ターンオーバー / ゲノム発現 … More
Except Principal Investigator
大腸菌 / protoporphyrinogen IX oxidase / ferrochelatase / spinach (Spinacia oleracea) / thymidylate synthase / cucumber (Cucumis sativus) / hemF gene of E.coli / soybean (Glycine max) / rice (Oryza sativa) / ダイズ / キューリ / シロイヌナズナ / CPOX / PPOX / ポルフィリン / プロトポルフィリノゲンIXオキシダーゼ / フェロキレテース / ホウレンソウ(Spinacia oleracea) / チミジル酸合成酵素遺伝子 / キューリ(Cucumis sativus) / 大腸菌(E.coli)のhemF遺伝子 / ダイズ(Glycine max) / イネ(Orgza sativa) / 細胞内ネットワーク / 遺伝的ネットワーク / 二重欠失株 / Chemical Genomics / Multiplex解析 / population変動 / 貞コピー可動型発現プラスミド / deep sequence / 一遺伝子欠失株 / 分子バーコード / ケミカルバイオロジー / 長期定常期 / 大腸菌population変動解析 / バーコード解析 / deep sequencing / stationary phase / chemical genomics / population dynamics / deletion collection / bar-code / E. coli / 無細胞タンパク質合成系 / 酵素反応速度論 / 酵素 Less
  • Research Projects

    (5 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (13 People)
  •  Strategy of a cell to survive during a long term stationary phase before cell proliferation.

    • Principal Investigator
      Mori Hirotada
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      System genome science
    • Research Institution
      Nara Institute of Science and Technology
  •  Genome wide analysis of translation efficiency by local structure of mRNA and nascent peptidePrincipal Investigator

    • Principal Investigator
      NAKAHIGASHI Kenji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      System genome science
    • Research Institution
      Keio University
  •  Comprehensive analysis of protein turnoverPrincipal Investigator

    • Principal Investigator
      NAKAHIGASHI Kenji
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      基礎ゲノム科学
    • Research Institution
      Keio University
  •  人工代謝系を用いたキネティクソーム解析技術の開発と大腸菌中心炭素代謝系への応用

    • Principal Investigator
      石井 伸佳
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bioinformatics/Life informatics
    • Research Institution
      Keio University
  •  Analysis of the genes for porphyrin biosynthetic pathway in higher plants utilizing the light-sensitive mutants of Escherichia coli

    • Principal Investigator
      INOKUCHI Hachiro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Molecular biology
    • Research Institution
      KYOTO UNIVERSITY

All 2016 2015 2014 2013 2012 2010 2009 2008 Other

All Journal Article Presentation Book

  • [Book] In Systems biology and biotechnology of Escherichia coli.(Yup LS ed)(Resources for Escherichia coli Systems Biology)2009

    • Author(s)
      Mori H, Yamamoto N, Dose H, Nakahigashi K, Datsenko KA, Wanner BL
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Book] 遺伝子医学MOOK(マルチオミクス(multi-omics)解析で見えてきた大腸菌の遺伝・環境変化に対する応答機構, 16)

    • Author(s)
      中東憲治、冨田勝
    • Publisher
      株式会社メディカルドウ
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Journal Article] Comprehensive identification of translation start sites by Tetracycline-inhibited Ribosome Profiling (TetRP)2016

    • Author(s)
      Kenji Nakahigashi Yuki Takai Michiko Kimura Nozomi Abe Toru Nakayashiki Yuh Shiwa Hirofumi Yoshikawa Barry L. Wanner Yasushi Ishihama Hirotada Mori
    • Journal Title

      DNA Res

      Volume: Mar 23 Issue: 3 Pages: 1-8

    • DOI

      10.1093/dnares/dsw008

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25250028
  • [Journal Article] GenoBase: comprehensive resource database of Escherichia coli K-122015

    • Author(s)
      Otsuka Y, Muto A, Takeuchi R, Okada C, Ishikawa M, Nakamura K, Yamamoto N, Dose H, Nakahigashi K, Tanishima S, Suharnan S, Nomura W, Nakayashiki T, Aref WG, Bochner BR, Conway T, Gribskov M, Kihara D, Rudd KE, Tohsato Y, Wanner BL & Mori H
    • Journal Title

      Nucleic Acids Research

      Volume: 43 Issue: D1 Pages: 606-617

    • DOI

      10.1093/nar/gku1164

    • NAID

      120005830851

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24310148, KAKENHI-PUBLICLY-25108716
  • [Journal Article] Effect of codon adaptation on codon-level and gene-level translation efficiency in vivo2014

    • Author(s)
      Nakahigashi K, Takai Y, Shiwa Y, Wada M, Honma M, Yoshikawa H, Tomita M, Kanai A, and Mori H
    • Journal Title

      BMC Genomics

      Volume: 15 Issue: 1 Pages: 1115-1115

    • DOI

      10.1186/1471-2164-15-1115

    • NAID

      120005830843

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24310148, KAKENHI-PROJECT-25250028
  • [Journal Article] A systematic survey of in vivo obligate chaperonin-dependent substrates.2010

    • Author(s)
      Fujiwara K, Ishihama Y, Nakahigashi K, Soga T, Taguchi H
    • Journal Title

      EMBO J 29(9)

      Pages: 1552-1564

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Journal Article] 13C-metabolic flux analysis for batch culture of Escherichia coli and its Pyk and Pgi gene knockout mutants based on mass isotopomer distribution of intracellular metabolites2010

    • Author(s)
      Toya Y, Ishii N, Nakahigashi K, Hirasawa T, Soga T, Tomita M, Shimizu K
    • Journal Title

      Biotechnol Prog 26(4)

      Pages: 975-992

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Journal Article] Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism2009

    • Author(s)
      中東憲治
    • Journal Title

      Molecular Systems Biology 5

      Pages: 306-306

    • NAID

      120005830850

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Journal Article] Update on the Keio collection of Escherichia coli single-gene deletion mutants2009

    • Author(s)
      Yamamoto N, Nakahigashi K, Nakamichi T, Yoshino M, Takai Y, Touda Y, Furubayashi A, Kinjyo S, Dose H, Hasegawa M, Datsenko KA, Nakayashiki T, Tomita M, Wanner BL, Mori H
    • Journal Title

      Mol Syst Biol 5

      Pages: 335-335

    • NAID

      120005830849

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Journal Article] Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism2009

    • Author(s)
      Nakahigashi K, Toya Y, Ishii N, Soga T, Hasegawa M, Watanabe H, Takai Y, Honma M, Mori H, Tomita M
    • Journal Title

      Mol Syst Biol 5

      Pages: 306-306

    • NAID

      120005830850

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Journal Article] マルチオミクス解析で見えてきた大腸菌の遺伝・環境変化に対する応答機構2009

    • Author(s)
      中東憲治
    • Journal Title

      遺伝子医学MOOK 16

      Pages: 152-158

    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] 遺伝子レベル、コドンレベルでの翻訳効率解析2014

    • Author(s)
      中東憲治、高井幸、志波優、兼崎友、吉川博文、森浩禎、冨田勝
    • Organizer
      第8回ゲノム微生物学会年会
    • Place of Presentation
      東京都世田谷区
    • Data Source
      KAKENHI-PROJECT-24310148
  • [Presentation] Deep Sequence Analysis of the relationship between sRNA- related factors and Dynamic Changes of sRNA Expression in Escherichia coli2013

    • Author(s)
      Motomu Matsui, Yoshiki Ikeda, Gakuto Makino, Masaru Tomita, Akio Kanai, Kenji Nakahigashi
    • Organizer
      JSBi2013
    • Place of Presentation
      東京都江戸川区
    • Data Source
      KAKENHI-PROJECT-24310148
  • [Presentation] Ribosome profilingによる翻訳開始部位の精密マッピング2013

    • Author(s)
      中東憲治
    • Organizer
      第7回日本ゲノム微生物学会年会
    • Place of Presentation
      長浜バイオ大学
    • Year and Date
      2013-03-10
    • Data Source
      KAKENHI-PROJECT-24310148
  • [Presentation] Precise mapping of Translational initiation sites by Ribosome profiling2013

    • Author(s)
      Kenji Nakahigashi
    • Organizer
      UK-Japan Systems Microbiology Workshop
    • Place of Presentation
      京都府京都市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24310148
  • [Presentation] Ribosome profilingと抗生物質の特性を利用した大腸菌翻訳開始部位の再アノテーション2012

    • Author(s)
      中東憲治
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-24310148
  • [Presentation] Comprehensive analysis of protein turnover (and its effect on metabolic simulation).2010

    • Author(s)
      Kenji Nakahigashi
    • Organizer
      UK-Japan Symposium of Systems and Synthetic Biology
    • Place of Presentation
      Guildford UK
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Comprehensive analysis of protein turnover2010

    • Author(s)
      Nakahigashi, K
    • Organizer
      UK-Japan Systems & Synthetic Biology workshop
    • Place of Presentation
      Surrey大学(英国)(招待講演)
    • Year and Date
      2010-09-14
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] 増殖、非増殖状態におけるタンパク質ターンオーバーの環境変化に伴う変化2010

    • Author(s)
      中東憲治
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Degradation and turnover of protein in growing and non-growing E. coli cell after environmental perturbation.2010

    • Author(s)
      Kenji Nakahigashi, Yasushi Ishihama, Toya Yoshihiro, Masaru Tomita
    • Organizer
      BMB2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Comprehensive analysis of protein turnover in aerobic and an aerobic continuous culture of E.coli2009

    • Author(s)
      中東憲治
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Systematic phenome analysis of Escherichia coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism2009

    • Author(s)
      中東憲治
    • Organizer
      UK-Japan Workshop on Systems Biology
    • Place of Presentation
      コスモスクエア国際交流センター大阪
    • Year and Date
      2009-09-23
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Systematic phenome analysis of E. coli multiple-knockout mutants reveals hidden reactions in central carbon metabolism2009

    • Author(s)
      Kenji Nakahigashi
    • Organizer
      UK-Japan Symposium of Systems Biology
    • Place of Presentation
      Osaka
    • Year and Date
      2009-09-23
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Comprehensive analysis of protein turnover in aerobic and anaerobic continuous culture of E. coli2009

    • Author(s)
      中東憲治, 石濱泰, 本間雅之, 高井幸, 冨田勝
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-11
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Protein turnover-omics : Comprehensive analysis of protein turnover in E. coli.2008

    • Author(s)
      Kenji Nakahigashi
    • Organizer
      International E. coli Alliance for Systerns Biology
    • Place of Presentation
      イギリス・ケンブリッジ
    • Year and Date
      2008-09-25
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Robustness of bacterial metabolic network. Views from Multi-Omics analysis.2008

    • Author(s)
      Kenji Nakahigashi
    • Organizer
      Design and Engineering of Microbial Genomes
    • Place of Presentation
      中央研究院, 台北, 台湾
    • Year and Date
      2008-11-26
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Multi-Omics解析からてくるバクテリア代謝の頑強性2008

    • Author(s)
      中東憲治
    • Organizer
      第18回玉川微生物資源ワークショップ
    • Place of Presentation
      三島
    • Year and Date
      2008-10-31
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Robustness of bacterial metabolic network. Views from Multi-Omics analysis.2008

    • Author(s)
      Kenji Nakahigashi
    • Organizer
      Design and Engineering of Microbial Genomes Academia Sinica Workshop
    • Place of Presentation
      Taipei, Taiwan
    • Year and Date
      2008-11-26
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Protein-turnoveromics ; global analyses of protein turnover in E. coli2008

    • Author(s)
      Kenji Nakahigashi, Yasushi Ishihama, Nobuyuki Ishii, Masaru Tomita
    • Organizer
      IECA2008
    • Place of Presentation
      Hixton UK
    • Year and Date
      2008-09-26
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Robustness of bacterial metabolic network. Views from multi-omics analysis2008

    • Author(s)
      Kenji Nakahigashi
    • Organizer
      Seminar at Center for Mathematical Modeling, University of Chile
    • Place of Presentation
      サンチアゴ, チリ国
    • Year and Date
      2008-12-27
    • Data Source
      KAKENHI-PROJECT-20310117
  • [Presentation] Hfqとデグラドソーム変異によるsRNAとmRNA翻訳への影響

    • Author(s)
      松井 求、池田 幸樹、牧野 岳都、志波 優、兼崎 友、吉川 博文、冨田 勝、金井 昭夫、中東 憲治
    • Organizer
      第37回日本分子学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24310148
  • [Presentation] 大腸菌の増殖停止・再開と RNA-seq 解析

    • Author(s)
      牧 泰史、大塚悠太、上田雅美、和田 明、古池 晶、吉田秀司、中東憲治、森 浩禎
    • Organizer
      第九回ゲノム微生物学会
    • Place of Presentation
      神戸大学(神戸)
    • Year and Date
      2015-03-06 – 2015-03-08
    • Data Source
      KAKENHI-PROJECT-24310148
  • 1.  MORI Hirotada (90182203)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 2.  ISHIHAMA YASUSHI (30439244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 3.  KANAI Akio (60260329)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  YAMADA Mamoru (30174741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MATSUNO Hiroshi (10181744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TAMURA Takeyuki (00437261)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TOHSATO Yukari (80346171)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MAKI Yasushi (60401733)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SAITO Natsumi (50287546)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KOSAKA Tomouki (70500453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  INOKUCHI Hachiro (20028195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  石井 伸佳 (80383941)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  片岡 正和 (90332676)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi