YAMAGATA KAZUYA 山縣和也

… Alternative Names

YAMAGATA Kazuya 山縣和也

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Researcher Number	70324770
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 教授
Affiliation (based on the past Project Information) *help	2015 – 2025: 熊本大学, 大学院生命科学研究部(医), 教授 2013 – 2015: 熊本大学, 大学院生命科学研究部, 教授 2013: 熊本大学, 大学院・生命科学研究部, 教授 2013: 熊本大学, 生命科学研究部, 教授 2012 – 2013: 熊本大学, その他の研究科, 教授 … More 2009 – 2011: Kumamoto University, 大学院・生命科学研究部, 教授 2010: 熊本大学, 生命科学研究部, 教授 2007 – 2009: Kumamoto University, 大学院・医学薬学研究部, 教授 2000 – 2006: 大阪大学, 医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Biological Sciences / Metabolomics / Biological Sciences Except Principal Investigator Metabolomics / Laboratory animal science / Basic Section 55020:Digestive surgery-related / Endocrinology / Radiation science / Biological Sciences
Keywords	Principal Investigator 糖尿病 / インスリン / HNF / 転写因子 / MODY / SIRT7 / サーチュイン / 遺伝子 / 褐色脂肪細胞 / 脂肪細胞 … More / insulin / インスリン分泌 / 褐色脂肪組織 / collectrin / gene / SNP / transcription factor / diabetes mellitus / HNF-1 / 肝臓 / β細胞 / hepatocyte nuclear factor / コレクトリン / シングルセル解析 / エピゲノム / 老化 / FGF21 / 寿命 / IMP2 / 糖新生 / 炎症 / アシル化修飾 / アシル化 / アセチル化 / PPARgamma / PPARg / PPARγ / エネルギー代謝 / サーチュン / DDB1 / 褐色脂肪 / ユビキチンリガーゼ複合体 / TR4 / ＳＩＲＴ７ / 脂肪肝 / SNARE complex / Exocytosis / Collectrin / Insulin / Diabetes mellitus / SNARE蛋白質 / 開口放出 / Diabetes Mellitus / ノックアウトマウス / HNF-4α / HNF4α / insulin resistance / impaired insulin secretion / PGC-1 / アディポネクチン / インスリン抵抗性 / インスリン分泌不全 / IGF-1 / development / growth / maturity-onset diabetes of the young (MODY) / 分化 / 発生 / 増殖 / グルコキナーゼ / SIRT / 核内受容体 / sirtuin / 代謝 / 脂質 / 標的遺伝子 / GRP78 / ERストレス / グルコース / HNF-1α / 糖尿病学 … More Except Principal Investigator 糖尿病 / 低酸素 / ヒト化マウス / 膵炎 / 野生マウス / 膵β細胞 / がん化耐性 / 腸内細菌叢 / 消化器癌 / ハダカデバネズミ / 腸内細菌 / Heparin-binding EGF-like growth factor (HB-EGF) / Growth factor / Gene therapy / Betacellulin / Differentioation / Regeneration / Diabetes mellitus / β cell / ベータセルリン / HB-EGF / 増殖因子 / 遺伝子治療 / ベータセルリン(Betacellulin) / 分化 / 再生 / β細胞 / インスリン分泌 / 転写因子 / マクロファージ増殖 / 動脈硬化症 / マクロファージ / 動脈硬化 / 2型糖尿病 / 超高磁場MRI / 脳アミロイド / アルツハイマー病 / 炭素13MRI / 炭素13含有化合物 / 炭素13 / アミロイドβ / MRI / 神経科学 / 認知症 / 脳・神経 / 可変型相同組替え / 行動 / 可変型相同組換え / 行動パターン / 脂肪細胞 / HNF / アディポネクチン / インスリン抵抗性 / インスリン分泌不全 Less

サーチュイン7（SIRT7）による糖代謝制御の統合的理解とその制御法の開発Principal Investigator
- Principal Investigator
  
  山縣和也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Elucidation of molecular mechanism of age-associated impaired insulin secretion by single cell analysisPrincipal Investigator
- Principal Investigator
  
  山縣和也
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kumamoto University
Regulation of glucose metabolism by SIRT7Principal Investigator
- Principal Investigator
  
  山縣和也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
消化器癌の革新的治療法開発を目指したハダカデバネズミ腸内細菌のマルチオミクス解析
- Principal Investigator
  
  馬場秀夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Molecular mechanism of metabolic regulation through protein acylationsPrincipal Investigator
- Principal Investigator
  
  Yamagata Kazuya
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kumamoto University
Identification of the metabolic roles of SIRT7 and the development of its regulation.Principal Investigator
- Principal Investigator
  
  Yamagata Kazuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kumamoto University
Identification of the multifaceted metabolic roles of SIRT7Principal Investigator
- Principal Investigator
  
  Yamagata Kazuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
The pathophysiological role of pancreatic beta-cell hypoxia in the progression of diabetes
- Principal Investigator
  
  SATO Yoshifumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Molecular mechanism of diabetes mellitus based on beta-cell transcription factor networkPrincipal Investigator
- Principal Investigator
  
  Yamagata Kazuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Proteasomal regulation of HNF4 alpha protein by hypoxia in pancreatic beta-cells.
- Principal Investigator
  
  SATO Yoshifumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
核小体因子ＳＩＲＴ７による脂質蓄積制御機構の解明Principal Investigator
- Principal Investigator
  
  山縣和也
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Genetic studies on unique phenotypes in MSM/Ms mouse strain
- Principal Investigator
  
  YAMAMURA Ken-ichi
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kumamoto University
MSM/Msマウスの疾患感受性・抵抗性に関する遺伝学的解析
- Principal Investigator
  
  山村研一
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kumamoto University
Molecular mechanism of type 2 diabetes based on pancreatic-cell enriched transcription factorsPrincipal Investigator
- Principal Investigator
  
  YAMAGATA Kazuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Development of amyloid^<13> C-MR imaging of the brain at 7T
- Principal Investigator
  
  HIRAI Toshinori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Kumamoto University
Common roles of macrophage proliferation and polarization in type 2 diabetes and atherosclerosis.
- Principal Investigator
  
  SENOKUCHI Takafumi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Generation of novel biomarker for pancreatic hormone secretion using shedding form of collectrinPrincipal Investigator
- Principal Investigator
  
  YAMAGATA Kazuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kumamoto University
Molecular mechanism of insulin secretion by a novel target of HNF1 colectrinPrincipal Investigator
- Principal Investigator
  
  YAMAGATA Kazuya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University
Study of glucose metabolism by HNF4α with knockout mousePrincipal Investigator
- Principal Investigator
  
  YAMAGATA Kazuya
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University
A novel classification of type 2 diabetes based on genome informaticsPrincipal Investigator
- Principal Investigator
  
  YAMAGATA Kazuya
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Genome informaticsに基づいた新しい糖尿病の分類体系の確立
- Principal Investigator
  
  松澤佑次
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Identification of molecular mechanism of pancreatic β-cell development and growth by hepatocyte nuclear factors(HNFs)Principal Investigator
- Principal Investigator
  
  YAMAGATA Kazuya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University
Establishment of the method for gene therapy of β cell regeneration by non-invasive gene delivery via pancreatic duct
- Principal Investigator
  
  MIYAGAWA Jun-ichiro
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Osaka University

[Book] Roles of HNF1α and HNF4α in pancreatic β-cells: lessons from a monogenic form of diabetes (MODY). (ed. Gerald Litwack), in The Pancreatic Beta Cell.2014
- Author(s)
  Yamagata, K.
- Publisher
  Elsevier Inc.
- Data Source
  KAKENHI-PROJECT-21220010
[Book] 内分泌・糖尿病・代謝内科352012
- Author(s)
  佐藤叔史, 山縣和也, 井上正宏
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24790932
[Book] 実験医学増刊活性酸素・ガス状分子による恒常性制御と疾患監修 : 山本雅之, 膵β細胞における低酸素応答と糖代謝異常2012
- Author(s)
  佐藤叔史, 山縣和也
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24790932
[Book] 糖尿病ナビゲーター第2版「転写因子によるβ細胞機能の調節」2010
- Author(s)
  山縣和也
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21390281
[Book] 糖尿病ナビゲーター2010
- Author(s)
  山縣和也, 他
- Publisher
  メヂィカルレビュー社
- Data Source
  KAKENHI-PROJECT-21390281
[Book] 糖尿病ナビゲーター第2版2010
- Author(s)
  山縣和也
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-21220010
[Book] 日本臨床新時代の糖尿病学(4)2008
- Author(s)
  山縣和也
- Publisher
  コレクトリン
- Data Source
  KAKENHI-PROJECT-19591049
[Book] 新時代の糖尿病学(4)コレクトリン2008
- Author(s)
  山縣和也
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-19591049
[Book] 単一遺伝子病とゲノム-若年性糖尿病MODY-2007
- Author(s)
  山縣和也
- Publisher
  ゲノム医学
- Data Source
  KAKENHI-PROJECT-19591049
[Book] メタボリックシンドローム時代の糖尿病研究の最前線2007
- Author(s)
  山縣和也
- Publisher
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-19591049
[Book] ジョスリン糖尿病デスクブック(翻訳)2007
- Author(s)
  山縣和也
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-19591049
[Book] 分子糖尿病学の進歩20072007
- Author(s)
  山縣和也
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-19591049
[Book] 現場の疑問に答える糖尿病診療Q&A2007
- Author(s)
  山縣和也
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19591049
[Book] 糖尿病学基礎と臨床2007
- Author(s)
  山縣和也
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-19591049
[Book] 内分泌・糖尿病科2007
- Author(s)
  山縣和也
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-19591049
[Book] 転写因子HNFとコレクトリン2007
- Author(s)
  山縣和也
- Publisher
  診断と治療社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590928
[Book] 糖尿病学 20072007
- Author(s)
  山縣和也
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-19591049
[Book] 糖尿病関連注射薬の新展開(インスリン・GLP-1・グルカゴン)2007
- Author(s)
  山縣和也
- Publisher
  フジメディカル出版
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Roles of β-Cell Hypoxia in the Progression of Type 2 Diabetes2024
- Author(s)
  Yamagata Kazuya、Tsuyama Tomonori、Sato Yoshifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 8 Pages: 4186-4186
- DOI
  10.3390/ijms25084186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K18302, KAKENHI-PROJECT-23K24388
[Journal Article] The Emerging Role of SIRT7 in Glucose and Lipid Metabolism2023
- Author(s)
  Yamagata Kazuya、Mizumoto Tomoya、Yoshizawa Tatsuya
- Journal Title
  
  Cells
  
  Volume: 13 Issue: 1 Pages: 48-48
- DOI
  10.3390/cells13010048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18302, KAKENHI-PROJECT-23K19568, KAKENHI-PROJECT-23K24388
[Journal Article] YAP/BRD4‐controlled ROR1 promotes tumor‐initiating cells and hyperproliferation in pancreatic cancer2023
- Author(s)
  Yamazaki Masaya、Hino Shinjiro、Usuki Shingo、Miyazaki Yoshihiro、Oda Tatsuya、Nakao Mitsuyoshi、Ito Takaaki、Yamagata Kazuya
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 14
- DOI
  10.15252/embj.2022112614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18302, KAKENHI-PROJECT-23K15075, KAKENHI-PROJECT-20K20467, KAKENHI-PROJECT-21K19513, KAKENHI-PROJECT-22K20921, KAKENHI-PROJECT-20KK0185, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03691, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-23K24388, KAKENHI-PROJECT-23K28002
[Journal Article] Hypoxia causes pancreatic β‐cell dysfunction and impairs insulin secretion by activating the transcriptional repressor BHLHE402023
- Author(s)
  Tsuyama Tomonori、Sato Yoshifumi、Yoshizawa Tatsuya、Matsuoka Takaaki、Yamagata Kazuya
- Journal Title
  
  EMBO reports
  
  Volume: 24 Issue: 8
- DOI
  10.15252/embr.202256227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18302, KAKENHI-PROJECT-22K08658, KAKENHI-PROJECT-22K16399, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K24388
[Journal Article] NAD+ salvage governs mitochondrial metabolism invigorating NK cell anti-immunity.2022
- Author(s)
  Guo X, Tan S, Wang T, Sun R, Li S, Tian P, Li M, Wang Y, Zhang Y, Yan Y, Dong Z, Yan L, Yue X, Wu Z, Li C, Yamagata K, Gao L, Ma C, Li T, Liang X
- Journal Title
  
  Hepatology
  
  Volume: - Issue: 2 Pages: 1-18
- DOI
  10.1002/hep.32658
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23K24388, KAKENHI-PROJECT-23K18302
[Journal Article] SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARg2.2021
- Author(s)
  Akter F, Tsuyama T, Yoshizawa T, Sobuz SU, Yamagata K
- Journal Title
  
  J Diabetes Invest
  
  Volume: Unknown
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22639
[Journal Article] Sirt7 Deficiency Attenuates Neointimal Formation Following Vascular Injury by Modulating Vascular Smooth Muscle Cell Proliferation2021
- Author(s)
  木村　優一
- Journal Title
  
  Circ J
  
  Volume: 85 Issue: 12 Pages: 2232-2240
- DOI
  10.1253/circj.CJ-20-0936
- NAID
  130008119968
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2021-11-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15852, KAKENHI-PROJECT-19H03654, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-16H06276
[Journal Article] Development of a DELFIA method to detect oncofetal antigen ROR1-positive exosomes2021
- Author(s)
  Daikuzono Hina、Yamazaki Masaya、Sato Yoshifumi、Takahashi Takashi、Yamagata Kazuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 578 Pages: 170-176
- DOI
  10.1016/j.bbrc.2021.08.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-16H06276
[Journal Article] SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARg2.2021
- Author(s)
  Akter F, Tsuyama T, Yoshizawa T, Sobuz SU, Yamagata K
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 10 Issue: 10 Pages: 1765-1774
- DOI
  10.1111/jdi.13567
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-20H04107, KAKENHI-PROJECT-16H06276
[Journal Article] SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARg2.2021
- Author(s)
  Akter F, Tsuyama T, Yoshizawa T, Sobuz SU, Yamagata K
- Journal Title
  
  J Diabetes Invest
  
  Volume: Unknown
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03711
[Journal Article] HNF1α controls glucagon secretion in pancreatic α-cells through modulation of SGLT12020
- Author(s)
  Sato Yoshifumi、Rahman Md Mostafizur、Haneda Masaki、Tsuyama Tomonori、Mizumoto Tomoya、Yoshizawa Tatsuya、Kitamura Tadahiro、Gonzalez Frank J.、Yamamura Ken-ichi、Yamagata Kazuya
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1866 Issue: 11 Pages: 165898-165898
- DOI
  10.1016/j.bbadis.2020.165898
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-20K17538, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-16H06276
[Journal Article] Cardiomyocyte Sirt (Sirtuin) 7 Ameliorates Stress-Induced Cardiac Hypertrophy by Interacting With and Deacetylating GATA42020
- Author(s)
  Yamamura Satoru、Izumiya Yasuhiro、Araki Satoshi、Nakamura Taishi、et al.
- Journal Title
  
  Hypertension
  
  Volume: 75 Issue: 1 Pages: 98-108
- DOI
  10.1161/hypertensionaha.119.13357
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08110, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-17K08279, KAKENHI-PROJECT-16H06276
[Journal Article] Impact of tissue macrophage proliferation on peripheral and systemic insulin resistance in obese mice with diabetes.2020
- Author(s)
  Morita Y, Senokuchi T, Yamada S, Wada T, Furusho T, Matsumura T, Ishii N, Nishida S, Nishida S, Motoshima H, Komohara Y, Yamagata K, Araki E.
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 8(1) Issue: 1 Pages: e001578-e001578
- DOI
  10.1136/bmjdrc-2020-001578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08889, KAKENHI-PROJECT-19K16982, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-16H06276
[Journal Article] Brown adipocyte-derived exosomal miR-132-3p suppress hepatic Srebf1 expression and thereby attenuate expression of lipogenic genes2020
- Author(s)
  Kariba Yuichi、Yoshizawa Tatsuya、Sato Yoshifumi、Tsuyama Tomonori、Araki Eiichi、Yamagata Kazuya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 530 Issue: 3 Pages: 500-507
- DOI
  10.1016/j.bbrc.2020.05.090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-20K17538, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-16H06276
[Journal Article] SIRT7 regulates the nuclear export of NF-κB p65 by deacetylating Ran2019
- Author(s)
  Sobuz Shihab U.、Sato Yoshifumi、Yoshizawa Tatsuya、Karim Fazlul、Ono Katsuhiko、Sawa Tomohiro、Miyamoto Yoichi、Oka Masahiro、Yamagata Kazuya
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 1866 Issue: 9 Pages: 1355-1367
- DOI
  10.1016/j.bbamcr.2019.05.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-17H03679, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-16H06276
[Journal Article] SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix2018
- Author(s)
  Fukuda Masatoshi、Yoshizawa Tatsuya et al.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 2833-2833
- DOI
  10.1038/s41467-018-05187-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06600, KAKENHI-PUBLICLY-17H05650, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17H04105, KAKENHI-PROJECT-15K11027, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-17K11014, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H05440
[Journal Article] SIRT7 is an important regulator of cartilage homeostasis and osteoarthritis development.2018
- Author(s)
  Korogi W, Yoshizawa T, Karim MF, Tanoue H, Yugami M, Sobuz SU, Hinoi E, Sato Y, Oike Y, Mizuta H, Yamagata K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 印刷中 Issue: 3 Pages: 891-897
- DOI
  10.1016/j.bbrc.2018.01.129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-16K09758
[Journal Article] Inhibition of local macrophage growth ameliorates focal inflammation and suppresses atherosclerosis.2018
- Author(s)
  Yamada S, Senokuchi T, Matsumura T, Morita Y, Ishii N, Fukuda K, Murakami S, Nishida S, Kawasaki S, Motoshima H, Furukawa N, Komohara Y, Fujiwara Y, Koga T, Yamagata K, Takeya M, Araki E
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 印刷中 Issue: 5 Pages: 994-1006
- DOI
  10.1161/atvbaha.117.310320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09835, KAKENHI-PROJECT-17K09863, KAKENHI-PROJECT-15K09394, KAKENHI-PROJECT-15K15348, KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-17H04201, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-16K09759, KAKENHI-PROJECT-16K09787, KAKENHI-PROJECT-17K16151
[Journal Article] Sirtuin 7 is involved in the consolidation of fear memory in mice2018
- Author(s)
  Islam Md Safiqul、Wei Fan-Yan、Ohta Kunimasa、Shigematsu Naoki、Fukuda Takaichi、Tomizawa Kazuhito、Yoshizawa Tatsuya、Yamagata Kazuya
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 495 Issue: 1 Pages: 261-266
- DOI
  10.1016/j.bbrc.2017.10.159
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05650, KAKENHI-PROJECT-16H05328
[Journal Article] Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response2018
- Author(s)
  Miyasato Yoshikazu、Yoshizawa Tatsuya、Sato Yoshifumi、Nakagawa Terumasa、Miyasato Yuko、Kakizoe Yutaka、Kuwabara Takashige、Adachi Masataka、Ianni Alessandro、Braun Thomas、Komohara Yoshihiro、Mukoyama Masashi、Yamagata Kazuya
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 5927-5927
- DOI
  10.1038/s41598-018-24257-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09268, KAKENHI-PROJECT-26461234, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-16H06276
[Journal Article] Angiopoietin-like protein 2 promotes chondrogenic differentiation during bone growth as a cartilage matrix factor.2018
- Author(s)
  Tanoue H, Morinaga J, Yoshizawa T, Yugami M, Itoh H, Nakamura T, Uehara Y, Masuda T, Odagiri H, Sugizaki T, Kadomatsu T, Miyata K, Endo M, Terada K, Ochi H, Takeda S, Yamagata K, Fukuda T, Mizuta H, Oike Y.
- Journal Title
  
  Osteoarthritis Cartilage
  
  Volume: 26 Issue: 1 Pages: 108-117
- DOI
  10.1016/j.joca.2017.10.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-15K06836
[Journal Article] Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice.2018
- Author(s)
  Zhao J, Tian Z, Kadomatsu T, Xie P, Miyata K, Sugizaki T, Endo M, Zhu S, Fan H, Horiguchi H, Morinaga J, Terada K, Yoshizawa T, Yamagata K, Oike Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 293 Issue: 5 Pages: 1596-1609
- DOI
  10.1074/jbc.m117.814996
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17F17121, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445, KAKENHI-PROJECT-18K19519
[Journal Article] Translational repression of a splice variant of cynomolgus macaque CXCL1L by its C-terminal sequence2017
- Author(s)
  Hisayuki Nomiyama, Naoki Osada, Ichiro Takahashi, Keiji Terao, Kazuya Yamagata, Osamu Yoshie
- Journal Title
  
  J. Interferon Cytokine Res.
  
  Volume: 37 Issue: 3 Pages: 129-138
- DOI
  10.1089/jir.2016.0085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26440202, KAKENHI-PROJECT-16H05328
[Journal Article] Hypoxia reduces HNF4alpha/MODY1 protein expression in pancreatic beta-cells by activating AMP-activated protein kinase.2017
- Author(s)
  Sato Y, Karim MF et al.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 印刷中 Issue: 21 Pages: 8716-8728
- DOI
  10.1074/jbc.m116.767574
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21238, KAKENHI-PROJECT-16K09758, KAKENHI-PROJECT-16H05328
[Journal Article] Transcriptional regulation of metabolism by SIRT1 and SIRT72017
- Author(s)
  Yamagata K, Yoshizawa T
- Journal Title
  
  Int. Rev. Cel. Mol. Bio.
  
  Volume: 335 Pages: 143-166
- DOI
  10.1016/bs.ircmb.2017.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05328
[Journal Article] SIRT7-dependent deacetylation of DDB1 regulates the expression of nuclear receptor TR42017
- Author(s)
  Karim MF, Yoshizawa T, Sobuz SU, Sato Y, Yamagata K
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 490 Issue: 2 Pages: 423-428
- DOI
  10.1016/j.bbrc.2017.06.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05328
[Journal Article] Sources of variation of transthyretin in healthy subjects in East and Southeast Asia: Clinical and experimental evidence for the effect of alcohol on transthyretin metabolism.2016
- Author(s)
  Jono H, Su Y, Obayashi K, Tanaka Y, Ishiguro A, Nishimura H, Shinriki S, Ueda M, Ikeda K, Yamagata K, Ichihara K, Ando Y; Scientific Committee for the Asia-Pacific Federation of Clinical Biochemistry.
- Journal Title
  
  Clin Chim Acta
  
  Volume: 458 Pages: 240-5
- DOI
  10.1016/j.cca.2016.04.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09318, KAKENHI-PROJECT-16H02771, KAKENHI-PROJECT-15H04841, KAKENHI-PROJECT-15K15006, KAKENHI-PROJECT-15K15195, KAKENHI-PROJECT-16H05328
[Journal Article] Role of SIRT7 in hepatic lipid metabolism.2015
- Author(s)
  Yamagata K, Karim MF, Sato Y, Yoshizawa T.
- Journal Title
  
  Diabetology International
  
  Volume: 6 Pages: 193-196
- NAID
  40020601082
- Data Source
  KAKENHI-PROJECT-26860697
[Journal Article] Role of SIRT7 in hepatic lipid metabolism2015
- Author(s)
  Yamagata K.
- Journal Title
  
  Diabetology International
  
  Volume: 6 Issue: 3 Pages: 193-196
- DOI
  10.1007/s13340-015-0226-y
- NAID
  40020601082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293212
[Journal Article] Roles of hepatic glucokinase in intertissue metabolic communication: Examination of novel liver-specific glucokinase knockout mice.2015
- Author(s)
  Hayashi H, Sato Y, Li Z, Yamamura KI, Yoshizawa T, Yamagata K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860697
[Journal Article] High resolution imaging of intracellular oxygen concentration by phosphorescence lifetime2015
- Author(s)
  Kurokawa H, Ito H, Inoue M, Tabata K, Sato Y, Yamagata K, Kizaka-Kondoh S, Kadonosono T, Yano S, Kamachi T.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 10657-10657
- DOI
  10.1038/srep10657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-25250012, KAKENHI-PROJECT-15H03003, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-25288028, KAKENHI-PROJECT-25293212
[Journal Article] Moderate hypoxia induces beta-cell dysfunction with HIF-1alpha independent gene expression changes2014
- Author(s)
  Sato Y
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 12 Pages: e114868-e114868
- DOI
  10.1371/journal.pone.0114868
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293212, KAKENHI-ORGANIZER-26111001, KAKENHI-PROJECT-26860697
[Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY32014
- Author(s)
  Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K
- Journal Title
  
  J. Diabetes Invest
  
  Volume: (in press) Pages: 407-423
- DOI
  10.1016/b978-0-12-800174-5.00016-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-25293212
[Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY32014
- Author(s)
  Ohki, T,, Utsu, Y., Morita, S., Karim, M.F., Sato, Y., Yoshizawa, T., Yamamura, K., Yamada, K., Kasayama, S., Yamagata, K.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010
[Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3.2014
- Author(s)
  Ohki T, Utsu Y, Morita S, Karim MF, Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 5 Pages: 513-516
- DOI
  10.1111/jdi.12237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790932, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-221S0001
[Journal Article] SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.2014
- Author(s)
  Yoshizawa T, Karim Md. F, Sato Y, Senokuchi T, Miyata K, Fukuda T, Go C, Tasaki M, Uchimura K, Kadomatsu T, Tian Z, Smolka C, Sawa T, Kakeya M, Tomizawa K, Ando Y, Araki E, Akaike T, Braun T, Oike Y, Bober E, Yamagata K.
- Journal Title
  
  Cell Metab.
  
  Volume: 9 Issue: 4 Pages: 712-721
- DOI
  10.1016/j.cmet.2014.03.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24790557, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25293212, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461361, KAKENHI-PROJECT-25870543, KAKENHI-PLANNED-26111008, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670207, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-26861112
[Journal Article] Inhibition of H3K18 deacetylation of SIRT7 by Myb-binding protein la (Mybbpla)2013
- Author(s)
  Karim Md F, Yoshizawa T, Sato Y, Sawa T, Tomizawa K, A kaike T and Yamagata K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 441 Issue: 1 Pages: 157-163
- DOI
  10.1016/j.bbrc.2013.10.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24790932, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25293212
[Journal Article] Identification of hepatocyte growth factor activator (Hgfac) gene as a target of HNF1α in mouse β-cells2012
- Author(s)
  Ohki T, Sato Y, Yoshizawa T, Yamamura K, Yamada K, Yamagata K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 425 Issue: 3 Pages: 619-624
- DOI
  10.1016/j.bbrc.2012.07.134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24790932, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23126521
[Journal Article] Anks4b, a novel target of HNF4α interacts with GRP78 and regulates endoplasmic reticulum stress-induced apoptosis in pancreatic β-cells2012
- Author(s)
  Sato Y, Hatta M, Karim MF, Sawa T, Wei F-Y, Sato S, Magnuson MA, Gonzalez FJ, Tomizawa K, Akaike T, Yoshizawa T, and Yamagata K
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Issue: 27 Pages: 23236-23245
- DOI
  10.1074/jbc.m112.368779
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24790932, KAKENHI-ORGANIZER-20117001, KAKENHI-PUBLICLY-23126521
[Journal Article] Voltage-gated K+channel KCNQ1 regulates insulin secretion in MIN6 β-cell line2011
- Author(s)
  Yamagata K., et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407 Issue: 3 Pages: 620-625
- DOI
  10.1016/j.bbrc.2011.03.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-23659797, KAKENHI-PROJECT-23791038
[Journal Article] Voltage-gated K^+channel KCNQ1 regulates insulin secretion in MIN6-cell line2011
- Author(s)
  Yamagata K, Senokuchi T, Lu M, Takemoto M, Karim MF, Go C, Sato Y, Hatta M, Yoshizawa T, Araki E, Miyazaki J, Song W-J
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407 Pages: 620-625
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Voltage-gated K^+ channel KCNQ1 regulates insulin secretion in MIN6 β-cell line.2011
- Author(s)
  Yamagata K., et al.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Deficit of Lys-tRNA Modification by Cdkal1 Causes the Development of Type 2 Diabetes in Mice2011
- Author(s)
  Wei F-Y, Suzuki T, Watanabe S, Kimura S, Kaitsuka T, Fujimura A, Matsui H, Atta M, Michiue H, Fontecave M, Yamagata K, Suzuki T, Tomizawa K
- Journal Title
  
  J. Clin. Invest
  
  Volume: 121 Pages: 3598-3608
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Voltage-gated K^+ channel KCNQ1 regulates insulin secretion in MIN6 β-cell line2011
- Author(s)
  Yamagata K., et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407 Pages: 620-625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Voltage-gated K^+channel KCNQ1 regulates insulin secretion in MIN6 b-cell line.2011
- Author(s)
  Yamagata K., et al.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220010
[Journal Article] Mitochondrial dysfunction and increased reactive oxygen species impair insulin secretion in sphingomyelin synthase 1 null mice2011
- Author(s)
  Yano M, Watanabe K, Yamamoto T, Ikeda K, Senokuchi T, Lu M, Kadomatsu T, Tsukano H, Ikawa M, Okabe M, Yamaoka S, Okazaki T, Umehara H, Gotoh T, Song WJ, Node K, Taguchi R, Yamagata K, Oike Y
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Pages: 3992-4002
- NAID
  120006957387
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Clinical features of Japanese type 2 diabetics with insulinogenic index in normal range after treatment of glucotoxicity2011
- Author(s)
  Iwahashi H, Akita E, Tokunaga A, Okita K, Horikawa Y, Imagawa A, Funahashi T, Shimomura I, Yamagata K
- Journal Title
  
  Diabetol Int
  
  Volume: 2 Pages: 208-213
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Voltage-gated K^+ channel KCNQ1 regulates insulin secretion in MIN6 β-cell line2011
- Author(s)
  Yamagata K., et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407 Pages: 620-625
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23126521
[Journal Article] Cellular hypoxia of pancreatic-cells due to high levels of oxygen consumption for insulin secretion in vitro2011
- Author(s)
  Sato Y, Endo H, Okuyama H, Takeda T, Iwahashi H, Imagawa A, Yamagata K, Shimomura I, Inoue M
- Journal Title
  
  J Biol. Chem
  
  Volume: 286 Pages: 12524-12532
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Similar incretin secretion in obese and non-obese Japanese subjects with type 2 diabetes2010
- Author(s)
  Kozawa J, Okita K, Imagawa A, Iwahashi H, Holst JJ, Yamagata K, Shimomura I
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 393 Pages: 410-413
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Synthesized basement membranes direct the differentiation of mouse embryonic stem cells into pancreatic lineages2010
- Author(s)
  Higuchi Y, Shiraki N, Yamane K, Qin Z, Mochitate K, Araki K, Senokuchi T, Yamagata K, Hara M, Kume K, Kume S
- Journal Title
  
  J Cell Sci
  
  Volume: 123 Pages: 2733-2742
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Glucose enhances collectrin protein expression in insulin-producing MIN6 cells2009
- Author(s)
  Saisho K, Fukuhara A, Yasuda T, Sato Y, Fukui K, Iwahashi H, Imagawa A, Hatta M, Shimomura I, Yamagata K
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 389 Pages: 133-137
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article]2009
- Author(s)
  山縣和也
- Journal Title
  
  糖尿病と遺伝子(診断と治療社)
  
  Pages: 73-76
- Data Source
  KAKENHI-PROJECT-21390281
[Journal Article] Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus2008
- Author(s)
  Yasuda K, Yamagata K(47番中11番目), Kasuga M
- Journal Title
  
  Nat Genet 40
  
  Pages: 1092-1097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] The -1535 promoter variant of the visfatin gene is associated with serum triglyceride and HDL-cholesterol levels in Japanese subjects2008
- Author(s)
  Tokunaga A, Miura A, Okauchi Y, Segawa K, Fukuhara A, Okita K, Takahashi M, Funahashi T, Miyagawa JI, Shimomura I, Yamagata K
- Journal Title
  
  Endocr J 55
  
  Pages: 205-212
- NAID
  10021265064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects2008
- Author(s)
  Miyake K, Yamagata K (23番中8番目), Kasuga M
- Journal Title
  
  J Hum Genet 53
  
  Pages: 174-180
- NAID
  10021248002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Mutations in the small heterodimer partner gene increase morbidity risk in Japanese type 2 diabetes patients2008
- Author(s)
  Enya M, Yamagata K(14番中9番目), Takeda J
- Journal Title
  
  Hum Mutat 29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men2008
- Author(s)
  Tamba S, Yamagata K(14番中11番目), Matsuzawa Y
- Journal Title
  
  Intern Med 47
  
  Pages: 1175-1180
- NAID
  130000122045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] A common P2 promoter polymorphism of the hepatocyte nuclear factor-4a gene is associated with insulin secretion in non-obese Japanese with type 2 diabetes2008
- Author(s)
  Tokunaga A, Horikawa Y, Fukuda-Akita E, Okita K, Iwahashi H, Shimomura I, Takeda J, Yamagata K
- Journal Title
  
  Endocr J 55
  
  Pages: 999-1004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Expression of HNF-4α(MODY1), HNF-1β(MODY5), and HNF-1 α(MODY3) proteins in the developing mouse pancreas2008
- Author(s)
  Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I
- Journal Title
  
  Gene Expr Patterns 8
  
  Pages: 96-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] PGC-1α Gly482Ser polymorphism is associated with the plasma adiponectin level in type 2 diabetic men2008
- Author(s)
  Okauchi Y, Iwahashi H, Okita K, Yuan M, Matsuda M, Tanaka T, Miyagawa J, Funahashi T, Horikawa Y, Shimomura I, Yamagata K
- Journal Title
  
  Endocr J 55
  
  Pages: 991-997
- NAID
  10023972934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan2008
- Author(s)
  Horikawa Y, Yamagata K (18番中6番目), Kasuga M
- Journal Title
  
  J Clin Endocrinol Metab 93
  
  Pages: 889-893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Impaired early insulin secretion in Japanese type 2 diabetes with metabolic syndrome2008
- Author(s)
  Fukuda-Akita E, Okita K, Okauchi Y, Ryo M, Nakamura T, Funahashi T, Iwahashi H, Shimomura I, Miyagawa J, Yamagata K
- Journal Title
  
  Diabetes Res Clin Pract 79
  
  Pages: 482-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Immunochemical detection of Nε-carboxyethyl lysine using a specific antibody2008
- Author(s)
  Nagai R, Fujiwara Y, Mera K, Yamagata K, Sakashita N, Takeya M
- Journal Title
  
  J Immunol Methods 332
  
  Pages: 112-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Collectrin is involved in the development of salt-sensitive hypertension by facilitating the membrane trafficking of apical membrane proteins via interaction with soluble N-ethylmaleiamide-sensitive factor attachment protein receptor complex2008
- Author(s)
  Yasuhara A, Yamagata K(12番中10番目), Makino H
- Journal Title
  
  Circulation 118
  
  Pages: 2146-2155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Macrophages and dendritic cells infiltrating islets with or without beta cells produce tumour necrosis factor-alpha in patients with recent-onset type 1 diabetes.2007
- Author(s)
  Uno S, Yamagata K et al.
- Journal Title
  
  Diabetologia (In press)
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] The HNF-1・-SNARE connection2007
- Author(s)
  Yamagata K, Nammo T, Sato Y, Saisho K, Shoda H, Fukui K
- Journal Title
  
  Diabetes Obes Metab Suppl 2
  
  Pages: 40-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Continuous stimulation of human glucagon-like peptide-1(7-36)amide in a mouse model(NOD)delays onset of autoimmune type 1 diabetes2007
- Author(s)
  Zhang J, Tokui Y, Yamagata K (13番中3番目)
- Journal Title
  
  Diabetologia 50
  
  Pages: 1900-1909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] The Role for HNF-1b-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells2007
- Author(s)
  Zhang Y, Wada J, Yamagata K (15番中8番目), Makino H
- Journal Title
  
  PLoS ONE 2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Reduction of visceral fat is associated with decrease in the number of metabolic risk factors in Japanese men2007
- Author(s)
  Okauchi Y, Yamagata K(12番中9番目), Matsuzawa Y
- Journal Title
  
  Diabetes Care 30
  
  Pages: 2392-2394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Macrophages and dendritic cells infiltrating islets with or without beta cells produce tumornecrosis factor-a in patients with recent-onset type 1 diabetes2007
- Author(s)
  Uno S, Yamagata K. et al.
- Journal Title
  
  Diabetologia 50
  
  Pages: 596-601
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] The HNF-1a-SNARE connection2007
- Author(s)
  Yamagata K., et. al.
- Journal Title
  
  Diabetes Obes Metab 2
  
  Pages: 40-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591049
[Journal Article] Neogenesis and proliferation of b-cells induced by human betacellulin gene transduction via retrograde pancreatic duct injection of an adenovirus vector2006
- Author(s)
  Tokui Y, Yamagata K. et al.
- Journal Title
  
  Biochem Biophys Res Commun 350
  
  Pages: 987-993
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] Hepatocyte nuclear factor-4α is essential for glucose-stimulated insulin secretion by pancreatic β-cells.2006
- Author(s)
  Miura A, Yamagata K et al.
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 5246-5257
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] Hepatocyte nuclear factor-4α is essential for glucose-stimulated insulin secretion by pancreatic β-cells.2006
- Author(s)
  Miura A, Yamagata K et al.
- Journal Title
  
  J Biol Chem (In press)
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] Hepatocyte nuclear factor-4α is essential for glucose-stimulated insulin secretion by pancreatic β-cells2006
- Author(s)
  Miura A, Yamagata K. et al.
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 5246-5257
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] Neogenesis and proliferation of beta-cells induced by human betacellulin gene transduction via retrograde pancreatic duct injection of an adenovirus vector.2006
- Author(s)
  Tokui Y, Yamagata K et al.
- Journal Title
  
  Biochem Biophys Res Commun. 350
  
  Pages: 987-993
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] Pancreatic beta and alpha cells are both decreased in patients with fulminant type 1 diabetes : a morphometrical assessment2005
- Author(s)
  Sayama K, Yamagata K et al.
- Journal Title
  
  Diabetologia 48
  
  Pages: 1560-1564
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] Functional characterization of the HNF4α isoform (HNF4α8) expressed in pancreatic β-cells2005
- Author(s)
  Ihara A, Yamagata K et al.
- Journal Title
  
  BBRC (in press)
- Data Source
  KAKENHI-PROJECT-14013038
[Journal Article] Pancreatic beta and alpha cells are both decreased in patients with fulminant type 1 diabetes : a morphometrical assessment2005
- Author(s)
  Sayama K, Yamagata K. et al.
- Journal Title
  
  Diabetologia 48
  
  Pages: 1560-1564
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation2005
- Author(s)
  Fukui K, Yamagata K. et al.
- Journal Title
  
  Cell Metabolism 2
  
  Pages: 373-384
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] Regenerative and therapeutic effects of heparin-binding epidermal growth factor-like growth factor on diabetes by gene transduction via retrograde pancreatic duct infection of adnovirus vector.2005
- Author(s)
  Kozawa J, Yamagata K et al.
- Journal Title
  
  Pancreas 31
  
  Pages: 32-42
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] The ER chaperone 150 kDa Oxygen Regulated Protein (ORP150) improves insulin resistance in type 2 diabetes mellitus2005
- Author(s)
  Ozawa K, Yamagata K et al.
- Journal Title
  
  Diabetes (in press)
- Data Source
  KAKENHI-PROJECT-14013038
[Journal Article] Functional characterization of the HNF4α isoform (HNF4α8) expressed in pancreatic β-cells2005
- Author(s)
  Ihara A, Yamagata K et al.
- Journal Title
  
  BBRC 329
  
  Pages: 984-990
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590938
[Journal Article] Functional characterization of the HNF4α isoform(HNF4α8) expressed in pancreatic β-cells2005
- Author(s)
  Ihara A, Yamagata K et al.
- Journal Title
  
  BBRC (in press)
- Data Source
  KAKENHI-PROJECT-15590938
[Journal Article] Regenerative and therapeutic effects of heparin-binding epidermal growth factor-like growth factor on diabetes by gene transduction via retrograde pancreatic duct injection of adenovirus vector2005
- Author(s)
  Kozawa J, Yamagata K. et al.
- Journal Title
  
  Pancreas 31
  
  Pages: 32-42
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] The ER chaperone 150 kDa Oxygen Regulated Protein(ORP150) improves insulin resistance in type 2 diabetes mellitus2005
- Author(s)
  Ozawa K, Yamagata K et al.
- Journal Title
  
  Diabetes (in press)
- Data Source
  KAKENHI-PROJECT-15590938
[Journal Article] The HNF-1 target Collectrin controls insulin exocytosis by SNARE complex formation.2005
- Author(s)
  Fukui K, Yamagata K et al.
- Journal Title
  
  Cell Metabolism 2
  
  Pages: 373-384
- Data Source
  KAKENHI-PROJECT-17590928
[Journal Article] The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.2005
- Author(s)
  Ozawa K, Yamagata K et al.
- Journal Title
  
  Diabetes 54
  
  Pages: 657-663
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590938
[Journal Article] Inhibitory effect of small heterodimer partner on hepatocyte nuclear factor 4 mediates bile acid-induced repression of human angiotensinogen gene.2004
- Author(s)
  Shimamoto Y, Yamagata K et al.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 7770-7776
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590938
[Journal Article] Overexpression of pituitary adenylate cyclase-activating polypeptide in islets inhibits hyperinsulinemia and islet hyperplasia in agouti yellow mice.2004
- Author(s)
  Tomimoto S, Yamagata K et al.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 309
  
  Pages: 796-803
- Data Source
  KAKENHI-PROJECT-14013038
[Journal Article] Overexpression of pituitary adenylate cyclase-activating polypeptide in islets inhibits hyperinsulinemia and islet hyperplasia in agouti yellow mice.2004
- Author(s)
  Tomimoto S, Yamagata K et al.
- Journal Title
  
  J.Pharmacol.Exp.Ther. 309
  
  Pages: 796-803
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590938
[Journal Article] Inhibitory effect of small heterodimer partner on hepatocyte nuclear factor 4 mediates bile acid-induced repression of human angiotensinogen gene.2004
- Author(s)
  Shimamoto Y, Yamagata K et al.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 7770-7776
- Data Source
  KAKENHI-PROJECT-14013038
[Journal Article] T130I mutation in HNF-4α gene is a loss-of-function mutation In hepatocytes and is associated with late-onset Type 2 diabetes mellitus in Japanese subjects.2003
- Author(s)
  Zhu Q, Yamagata K et al.
- Journal Title
  
  Diabetologia 46
  
  Pages: 567-573
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590938
[Journal Article] Overexpression of dominant-negative mutant HNF-1α in pancreatic β-cells causes abnormal islet architecture with decreased expression of E-cadherin, reduced β-cell proliferation and diabetes.2002
- Author(s)
  Yamagata K. et al.
- Journal Title
  
  Diabetes 51
  
  Pages: 114-123
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013038
[Journal Article] Anks4b, a novel target of HNF4α interacts with GRP78 and regulates endoplasmic reticulum stress-induced apoptosis in pancreaticβ-cells
- Author(s)
  Sato Y, Hatta M, Karim Fazlul, Sawa T, Wei F-W, Sato S, Magnuson MA, Gonzalez FJ, Tomizawa K, Akaike T, Yoshizawa T, Yamagata K
- Journal Title
  
  J Biol. Chem
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21390281
[Patent] 2型糖尿病および動脈硬化のマーカー、およびこれを検出するためのプローブならびにプライマー2003
- Inventor(s)
  山縣和也
- Industrial Property Number
  2003-079426
- Filing Date
  2003-03-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14013038
[Presentation] 脱アセチル化酵素SIRT7による肝糖新生制御機構の解明2023
- Author(s)
  水本智也、佐藤叔史、津山友徳、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 低酸素誘導性インスリン分泌不全の分子機構の解明2023
- Author(s)
  津山友徳、佐藤叔史、松岡孝昭、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K18302
[Presentation] 脱アセチル化酵素SIRT7による肝糖新生制御機構の解明2023
- Author(s)
  水本智也、佐藤叔史、津山友徳、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K18302
[Presentation] 膵β細胞における低酸素誘導因子ATF3の役割2023
- Author(s)
  佐藤叔史、津山友徳、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 会長講演：糖尿病発症機構の解明を目指して2023
- Author(s)
  山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 膵β細胞における低酸素誘導因子ATF3の役割2023
- Author(s)
  佐藤叔史、津山友徳、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K18302
[Presentation] 低酸素誘導性インスリン分泌不全の分子機構の解明2023
- Author(s)
  津山友徳、佐藤叔史、松岡孝昭、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 経管栄養の実施により高血糖高浸透圧症候群を発症した症例2023
- Author(s)
  大村和寛、本島寛之、高木優樹、蓑田理彦、荒木栄一、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 加齢による２型糖尿病発症機序の解明、サルコペニア有病率の検討（合志スタディ）2023
- Author(s)
  羽根田昌樹、前田沙梨恵、福田一起、宮川克俊、清原由紀夫、古賀荒太郎、阪口雅司、瀬ノ口隆文、松村剛、荒木栄一、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 糖尿病発症機構の解明を目指して2023
- Author(s)
  山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18302
[Presentation] 当院で定期健診を受けた糖尿病有病者の新規がん発生に関する研究2023
- Author(s)
  本島寛之、園田実喜子、宮崎春美、高木優樹、大村和寛、蓑田理彦、松本さ月、荒木栄一、山縣和也
- Organizer
  第６１回日本糖尿病学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] 日本人の加齢による２型糖尿病発症機序の解明（合志スタディ）2023
- Author(s)
  羽根田昌樹、福田一起、宮川克俊、清原由紀夫、古賀荒太郎、水流添　覚、古川昇、津山友徳、阪口雅司、瀬ノ口隆文、松村剛、山縣和也、荒木栄一
- Organizer
  第６６回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K24388
[Presentation] Regulation of Metabolism by nuclear factors2021
- Author(s)
  Kazuya Yamagata
- Organizer
  The Quadruple symposium-2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22639
[Presentation] HNF1a controls both insulin and glucagon secretion in pancreatic islets.2021
- Author(s)
  Yamagata K
- Organizer
  The 64th Annual Meeting of the Japan Diabetes Society
- Invited
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] Regulation of Metabolism by nuclear factors2021
- Author(s)
  Kazuya Yamagata
- Organizer
  The Quadruple symposium-2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] NAD依存性酵素の高次生体機能調節機構―エネルギー代謝を超えてー　SIRT7による加齢関連疾患の発症制御2021
- Author(s)
  山縣和也
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] 膵β細胞と低酸素ストレス2020
- Author(s)
  山縣和也
- Organizer
  第58回日本糖尿病学会九州地方会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22639
[Presentation] 老化関連疾患の克服による健康寿命の延伸2020
- Author(s)
  山縣和也
- Organizer
  第70回日本体質医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] HNF-1αによる膵α細胞機能制御メカニズムの解明2020
- Author(s)
  佐藤叔史、Md Mostafizur Rahman、羽根田昌樹、水本智也、津山友徳、吉澤達也、北村忠弘、Frank J Gonzalez、山村研一、山縣和也
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] HNF-1αによる膵α細胞機能制御メカニズムの解明2020
- Author(s)
  佐藤叔史、Md Mostafizur Rahman、羽根田昌樹、水本智也、津山友徳、吉澤達也、北村忠弘、Frank J Gonzalez、山村研一、山縣和也
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K22639
[Presentation] 膵β細胞と低酸素ストレス2020
- Author(s)
  山縣和也
- Organizer
  第58回日本糖尿病学会九州地方会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] 老化関連疾患の克服による健康寿命の延伸2020
- Author(s)
  山縣和也
- Organizer
  第70回日本体質医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22639
[Presentation] 低酸素ストレスはBhlhe40-Mafa経路を介してインスリン分泌不全を誘導する2019
- Author(s)
  津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K22639
[Presentation] Regulation of aging-related diseases by sirtuin 7 (SIRT7)2019
- Author(s)
  Kazuya Yamagata
- Organizer
  France-Japan Symposium. Implications of senescence in age related disorders: Towards healthy aging.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22639
[Presentation] 脱アセチル化酵素SIRT7によるNF-kB p65の核外輸送制御メカニズムの解明2019
- Author(s)
  佐藤叔史、Sobuz Shihab U.、吉澤達也、Fazlul Karim、小野勝彦、澤智裕、宮本洋一、岡正啓、山縣和也
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K22639
[Presentation] 脱アセチル化酵素SIRT7によるNF-kB p65の核外輸送制御メカニズムの解明2019
- Author(s)
  佐藤叔史、Sobuz Shihab U.、吉澤達也、Fazlul Karim、小野勝彦、澤智裕、宮本洋一、岡正啓、山縣和也
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] 低酸素誘導性BHLHE40によるβ細胞機能低下機序の解明2019
- Author(s)
  佐藤叔史、津山友徳、吉澤達也、松岡孝昭、山縣和也
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] 低酸素誘導性BHLHE40によるβ細胞機能低下機序の解明2019
- Author(s)
  佐藤叔史、津山友徳、吉澤達也、松岡孝昭、山縣和也
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K22639
[Presentation] 低酸素ストレスはBhlhe40-Mafa経路を介してインスリン分泌不全を誘導する2019
- Author(s)
  津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19H03711
[Presentation] エクソソームを介した褐色脂肪組織から肝臓への新たな生理作用の解明2018
- Author(s)
  狩場佑一、吉澤達也、山縣和也
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] Bhlhe40-Mafa経路を介した低酸素ストレスによるインスリン分泌抑制2018
- Author(s)
  津山友徳、佐藤叔史、吉澤達也、松岡孝昭、山縣和也
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 低酸素応答因子HIF-1/AMPKによる膵β細胞障害の分子機構2018
- Author(s)
  佐藤叔史、山縣和也
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 急性尿細管障害におけるSIRT7の機能解明2017
- Author(s)
  宮里腎和、吉澤達也、中川輝政、柿添　豊、桒原孝成、安達政隆、向山政志、山縣和也
- Organizer
  第２１回日本心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] SIRT7とアンチエイジング2017
- Author(s)
  山縣和也、吉澤達也
- Organizer
  脳心血管抗加齢研究会2017
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 核内脱アシル化酵素SIRT7は軟骨細胞分化を制御し、変形性膝関節症の発症に関与する2017
- Author(s)
  興梠　航、吉澤達也、山縣和也
- Organizer
  第３５回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 膵β細胞低酸素によるHNF4蛋白低下メカニズムの解明2017
- Author(s)
  佐藤叔史、津山友徳、佐藤ちなみ、Md. Fazlul Karim、吉澤達也、井上正宏、山縣和也
- Organizer
  日本生化学学会九州支部例会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] SIRT7によるエネルギー代謝制御2017
- Author(s)
  山縣和也、吉澤達也
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 脱アシル化酵素SIRT7によるOsterixの転写活性化は骨形成に重要である2017
- Author(s)
  吉澤達也、福田雅俊、竹田秀、山縣和也
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] SIRT7によるエネルギー代謝制御2016
- Author(s)
  吉澤達也、山縣和也
- Organizer
  第３７回日本肥満学会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] Deletion of Sirtuin 7 Ameliorates Cisplatin-Induced Acute Kidney Injury through Regulation of Inflammatory Response.2016
- Author(s)
  Yoshikazu Miyasato, Tatsuya Yoshizawa, Terumasa Nakagawa, Yutaka Kakizoe, Yuichiro Izumi, Takashige Kuwabara, Masataka Adachi, Eva Bober, Masashi Mukoyama, Kazuya Yamagata
- Organizer
  The American Society of Nephrology (ASN) Kidney Week 2016 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] ARNTはARNT/HIF-１αによる血管形成とは独立して直接骨芽細胞の分化を促進する2016
- Author(s)
  福田雅俊、吉澤達也、池亀美華、竹田秀、山縣和也
- Organizer
  第34回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 核内脱アセチル化酵素SIRT7はOsterixを介して骨形成を制御する2016
- Author(s)
  吉澤達也、福田雅俊、興梠航、竹田秀、山縣和也
- Organizer
  第34回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] SIRT7による代謝制御作用2016
- Author(s)
  山縣和也、吉澤達也
- Organizer
  脳心血管抗加齢研究会２０１６
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] 代謝制御におけるSIRT7の多様な役割2016
- Author(s)
  吉澤達也、山縣和也
- Organizer
  第８９回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H05328
[Presentation] Hypoxia reduces HNF4a/MODY1 protein expression of pancreatic b-cells2015
- Author(s)
  Yamagata K.
- Organizer
  Keystone symposia
- Place of Presentation
  Kyoto
- Year and Date
  2015-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] β細胞低酸素による転写因子HNF4α蛋白発現低下機序の検討2015
- Author(s)
  佐藤叔史、佐藤ちなみ、吉澤達也、井上正宏、山縣和也
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26860697
[Presentation] The molecular mechanisms of impaired insulin secretion in diabetes mellitus2013
- Author(s)
  Kazuya Yamagata
- Organizer
  The 2^<nd> Shandong University-Kumamoto University Medical Symposium
- Place of Presentation
  China (Shandong Univ)
- Year and Date
  2013-12-16
- Data Source
  KAKENHI-PROJECT-21220010
[Presentation] Moderate hypoxia impairs glucose stimulated insulin secretion and accelerates apoptosis in pancreatic-cellsModerate hypoxia impairs glucose stimulated insulin secretion and accelerates apoptosis in pancreaticβ-cells2013
- Author(s)
  Yoshifumi Sato, Masahiro Inoue, Kazuya Yamagata
- Organizer
  Beta Cell Workshop 2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  第５６回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本・熊本市現代美術館
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史, 井上正宏, 山縣和也
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] Hypoxic stress and pancreatic β-cell dysfunction2013
- Author(s)
  Kazuya Yamagata、Yoshifumi Sato
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] Moderate hypoxia impairs glucose stimulated insulin secretion and accelerates apoptosis in pancreaticβ-cells.2013
- Author(s)
  Yoshifumi Sato, Masahiro Inoue, Kazuya Yamagata
- Organizer
  Beta Cell Workshop 2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸・神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] Hypoxic stress and pancreatic beta-cell dysfunction2013
- Author(s)
  Kazuya Yamagata
- Organizer
  第５６回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本・メルパルク熊本
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] 軽度低酸素による膵β細胞障害機構の検討2013
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  ：第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 核小体因子SIRT7による肝臓内脂質蓄積制御機構2012
- Author(s)
  山縣和也
- Organizer
  第33回日本肥満学会
- Place of Presentation
  グランビア京都（京都府）
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PUBLICLY-23126521
[Presentation] Analysis of a novel HNF4alpha; target gene Anks4b in pancreatic beta-cells2012
- Author(s)
  Yamagata K et al.
- Organizer
  72nd American Diabetes Association scientific sessions
- Place of Presentation
  Philadelphia/Pennsylvania/USA
- Data Source
  KAKENHI-PROJECT-21220010
[Presentation] Analysis of a novel HNF4a target gene Anks4b in pancreatic b-cells2012
- Author(s)
  Kazuya Yamagata, Yoshifumi Sato, Md. Fazlul Karim, Tatsuya Yoshizawa
- Organizer
  72^<nd> American Diabetes Association scientific sessions L
- Place of Presentation
  Hunter Limbaugh, USA (Philadelphia/Pennsylvania)
- Data Source
  KAKENHI-PROJECT-21220010
[Presentation] 膵島低酸素による転写因子HNF-4αの発現低下機構の解析2012
- Author(s)
  佐藤叔史, 井上正宏, 下村伊一郎, 山縣和也
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] Sirtuinによる肝臓脂肪蓄積制御機構2012
- Author(s)
  山縣和也
- Organizer
  第62回日本体質医学会総会
- Place of Presentation
  大阪国際会議場（大阪府）
- Year and Date
  2012-11-03
- Invited
- Data Source
  KAKENHI-PUBLICLY-23126521
[Presentation] Cellular hypoxia caused dysregulation of HNF4α expression in pancreatic-βcells2012
- Author(s)
  Yoshifumi Sato, Masahiro Inoue, Iichiro Shimomura, Kazuya Yamagata
- Organizer
  The 33rd NAITO CONFERENCE
- Place of Presentation
  CHA^^TERAISE^'Gateaux Kingdom SAPPORO(北海道)
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] 新規HNF4α標的遺伝子Anks4bによるアポトーシス制御機構2012
- Author(s)
  山縣和也
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜（横浜）
- Data Source
  KAKENHI-PROJECT-24790932
[Presentation] HIF-1αによる酸素消費の抑制は膵β細胞の細胞内低酸素を回避する2011
- Author(s)
  佐藤叔史、今川彰久、山縣和也、下村伊一郎、井上正宏
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] 膵β細胞と低酸素ストレス2011
- Author(s)
  山縣和也
- Organizer
  第5回Diabetes Leading-edge Conferenceロイヤルオークホテル
- Place of Presentation
  滋賀
- Year and Date
  2011-08-07
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] シンポジウム1「酸素センサーとシグナル応答」膵β細胞における低酸素ストレス2011
- Author(s)
  山縣和也
- Organizer
  第17回MPO研究会
- Place of Presentation
  アークホテル熊本(熊本)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] NAD依存性脱アセチル化酵素SIRT7の糖代謝への関与の検討2011
- Author(s)
  瀬ノ口隆文、郷知佐、吉澤達也、宮田敬士、Eva Bober、尾池雄一、荒木栄一、山縣和也
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] 核小体因子SIRT7による糖脂質代謝制御2011
- Author(s)
  山縣和也
- Organizer
  第32回日本肥満学会淡路夢舞台国際会議場
- Place of Presentation
  兵庫
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] Analysis of a novel HNF4 target gene Anks4b in pancreaticβ-cells2011
- Author(s)
  Yoshifumi Sato, Mitsutoki Hatta, Md. Fazlul Karim, Tatsuya Yoshizawa, Kazuya Yamagata
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] 2型糖尿病疾患感受性遺伝子KCNQ1によるインスリン分泌2011
- Author(s)
  山縣和也
- Organizer
  第49回日本糖尿病学会九州地方会
- Place of Presentation
  アクロス福岡(博多)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] 核小体因子SIRT7による糖脂質代謝制御2011
- Author(s)
  山縣和也
- Organizer
  第32回日本肥満学会
- Place of Presentation
  淡路夢舞台会議場(兵庫県)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PUBLICLY-23126521
[Presentation] Regulation of insulin secretion by HNF4 transcription factor2010
- Author(s)
  山縣和也
- Organizer
  BMB2010(第33回日本分子生物学会・第83回日本生化学会大会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] 膵β細胞における新規HNF-4標的遺伝子Anks4bの機能解析BMB20102010
- Author(s)
  八田光世、MD. Fazlul Karim、佐藤叔史、瀬ノ口隆文、山縣和也
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会
- Place of Presentation
  神戸ポートピアホテル(兵庫)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] Regulation of insulin secretion by HNF-4 transcription factor BMB20102010
- Author(s)
  Kazuya Yamagata
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会
- Place of Presentation
  神戸ポートピアホテル(兵庫)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] Regulation of insulin secretion by HNF-4 transcription factor2010
- Author(s)
  Kazuya Yamagata
- Organizer
  第33回日本分子生物学会・第83回日本生化学会大会
- Place of Presentation
  神戸ポートピアホテル(兵庫)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21220010
[Presentation] Regulation of insulin secretion by HNF4 transcription factor2010
- Author(s)
  山縣和也
- Organizer
  BMB2010(第33回日本分子生物学会・第83回日本生化学会大会)
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21220010
[Presentation] Regulation of insulin secretion by HNF transcription factors2009
- Author(s)
  Kazuya Yamagata
- Organizer
  The 4^<th> International Workshop on Cell Regulations in Division and Arrest
- Place of Presentation
  Okinawa OIST Seaside House
- Data Source
  KAKENHI-PROJECT-21390281
[Presentation] レクチャー「糖尿病と遺伝子」MODY2009
- Author(s)
  山縣和也
- Organizer
  第43回糖尿病学の進歩
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] HNF転写因子と膵β細胞2008
- Author(s)
  山縣和也
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 転写因子異常によるインスリン合成分泌障害2008
- Author(s)
  山縣和也
- Organizer
  糖尿病学の進歩
- Place of Presentation
  高松
- Year and Date
  2008-02-15
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 核内受容体HNF4αによる膵β細胞制御機構BMB20082008
- Author(s)
  山縣和也
- Organizer
  第31回日本分子生物学会・第81回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 転写因子異常によるインスリン合成分泌障害2008
- Author(s)
  山縣和也
- Organizer
  第42回糖尿病学の進歩
- Place of Presentation
  高松
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] Regulation of insulin secretion from pancreatic β-cells by hepatocyte nuclear factor2008
- Author(s)
  Kazuya Yamagata
- Organizer
  Global COE Liaison Laboratory Seminar
- Place of Presentation
  Kumamoto
- Year and Date
  2008-01-23
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] インスリン分泌不全における転写因子の関与2008
- Author(s)
  山縣和也
- Organizer
  FANTASY
- Place of Presentation
  東京
- Year and Date
  2008-02-02
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 核内受容体HNF4αこよる膵β細胞制御機構2008
- Author(s)
  山縣和也
- Organizer
  第3 1回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] シンポジウム3 : 糖尿病発症機序研究の進展「2型糖尿病の遺伝因子とインスリン分泌不全」2008
- Author(s)
  山縣和也
- Organizer
  第46回日本糖尿病学会九州地方会
- Place of Presentation
  久留米
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] HNF転写因子によるインスリン分泌制御とその破綻2007
- Author(s)
  山縣和也
- Organizer
  Islet Biology研究会
- Place of Presentation
  東京
- Year and Date
  2007-07-27
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 転写因子によるインスリン分泌制御とその破綻2007
- Author(s)
  山縣和也
- Organizer
  宮崎大学医学部シンポジウム
- Place of Presentation
  宮崎
- Year and Date
  2007-12-25
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 転写因子による膵β細胞機能制御2007
- Author(s)
  山縣和也
- Organizer
  東北インスリン研究会
- Place of Presentation
  仙台
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] コレクトリンによる糖代謝制御機構の解明とインスリン分泌の新たなバイオマーカーの開発2007
- Author(s)
  山縣和也
- Organizer
  病態代謝研究会
- Place of Presentation
  東京
- Year and Date
  2007-10-20
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] マウス発生過程におけるHNF-4α、HNF-1α、HNF-1βの発現様式の検討2007
- Author(s)
  山縣和也
- Organizer
  日本内分泌学会
- Place of Presentation
  東京
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] リリー賞受賞講演 : 膵β細胞転写因子によるインスリン分泌制御とその破綻2007
- Author(s)
  山縣和也
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] シンポジウム18「転写因子と糖尿病」2型糖尿病の膵β細胞障害における転写因子の関与2007
- Author(s)
  山縣和也、堅田温子、佐藤叔史、福井健司
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 2型糖尿病におけるインスリン分泌不全の意義2007
- Author(s)
  山縣和也
- Organizer
  TOYAMA Diabetes Updated Seminar
- Place of Presentation
  富山
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 核内レセプターHNF4と糖尿病2007
- Author(s)
  山縣和也
- Organizer
  VD3研究会
- Place of Presentation
  東京
- Year and Date
  2007-06-18
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 12007
- Author(s)
  山縣和也
- Organizer
  日本糖尿病学会
- Place of Presentation
  仙台
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] 12007
- Author(s)
  山縣和也
- Organizer
  東京インスリン分泌研究会
- Place of Presentation
  東京
- Year and Date
  2007-09-26
- Data Source
  KAKENHI-PROJECT-19591049
[Presentation] HIF-1非依存的発現調節を介した軽度低酸素によるβ細胞障害メカニズムの検討
- Author(s)
  佐藤叔史、井上正宏、吉澤達也、山縣和也
- Organizer
  第12回がんとハイポキシア研究会
- Place of Presentation
  佐賀
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26860697
[Presentation] The molecular mechanisms of impaired insulin secretion in diabetes mellitus
- Author(s)
  Kazuya Yamagata
- Organizer
  The 2nd Shandong University-Kumamoto University Medical Symposium
- Place of Presentation
  中国（Shandong Univ）
- Data Source
  KAKENHI-PROJECT-21220010
[Presentation] 核内因子による糖脂質代謝制御
- Author(s)
  山縣和也
- Organizer
  平成２５年度大阪糖尿病アカデミー特別講演
- Place of Presentation
  大阪（グランビア大阪）
- Invited
- Data Source
  KAKENHI-PROJECT-21220010
[Presentation] HIF-1非依存的発現調節を介した軽度低酸素によるβ細胞障害メカニズムの検討
- Author(s)
  佐藤叔史、井上正宏、吉澤達也、山縣和也
- Organizer
  第3７回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26860697
[Presentation] SIRT7による糖脂質代謝制御
- Author(s)
  山縣和也
- Organizer
  第３５回日本肥満学会
- Place of Presentation
  宮崎
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] Hypoxic stress and pancreatic β-cell dysfunction
- Author(s)
  山縣和也
- Organizer
  第５６回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本（メルパルク熊本）
- Data Source
  KAKENHI-PROJECT-21220010
[Presentation] 膵β細胞におけるHNF4α標的遺伝子Anks4bの機能解析
- Author(s)
  作永真由美、佐藤叔史、吉澤達也、山縣和也
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-26860697
[Presentation] Hypoxic stress and pancreatic beta-cell dysfunction
- Author(s)
  Kazuya Yamagata
- Organizer
  第５７回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] 核内因子による糖脂質代謝制御
- Author(s)
  山縣和也
- Organizer
  平成２５年度大阪糖尿病アカデミー特別講演
- Place of Presentation
  大阪・グランビア大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25293212
[Presentation] β細胞低酸素による転写因子発現低下メカニズムの検討
- Author(s)
  佐藤叔史、井上正宏、山縣和也
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-26860697

1. SATO Yoshifumi (90622598)

# of Collaborated Projects: 7 results

# of Collaborated Products: 43 results
2. Yoshizawa Tatsuya (40313530)

# of Collaborated Projects: 5 results

# of Collaborated Products: 29 results
3. MIYAGAWA Jun-ichiro (00127721)

# of Collaborated Projects: 4 results

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# of Collaborated Projects: 4 results

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# of Collaborated Projects: 2 results

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27. OKAMOTO Shiki (40342919)

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28. YAMAMOTO Koji (60304060)

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49. 桑原孝成

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50. 安東由喜雄

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YAMAGATA KAZUYA 山縣 和也

YAMAGATA Kazuya 山縣 和也

Research Projects

Research Products

Co-Researchers

サーチュイン7（SIRT7）による糖代謝制御の統合的理解とその制御法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of molecular mechanism of age-associated impaired insulin secretion by single cell analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of glucose metabolism by SIRT7Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of metabolic regulation through protein acylationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the metabolic roles of SIRT7 and the development of its regulation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the multifaceted metabolic roles of SIRT7Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of diabetes mellitus based on beta-cell transcription factor networkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

核小体因子ＳＩＲＴ７による脂質蓄積制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

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Principal Investigator

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Principal Investigator

Project Period (FY)

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Research Institution

Molecular mechanism of type 2 diabetes based on pancreatic-cell enriched transcription factorsPrincipal Investigator

Principal Investigator

YAMAGATA KAZUYA 山縣和也

YAMAGATA Kazuya 山縣和也