• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

TAKAHASHI Masaharu  高橋 雅春

ORCIDConnect your ORCID iD *help
… Alternative Names

高橋 雅春  タカハシ マサハル

Less
Researcher Number 70326841
Other IDs
External Links
Affiliation (Current) 2025: 自治医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help 2014: 自治医科大学, 医学部, 講師
2010 – 2012: 自治医科大学, 医学部, 講師
2008: 自治医科大学, 医学部・感染免疫学講座ウイルス学部門, 講師
2003 – 2008: JICHI MEDICAL SCHOOL, SCHOOL OF MEDICINE, ASSOCIATE PROFESSOR, 医学部, 講師
2000 – 2002: 自治医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Virology
Except Principal Investigator
Virology / Virology
Keywords
Principal Investigator
HEV RNA / reservoir / E型肝炎ウイルス / wild boar / swine / antibodies to HEV / zoonosis / hepatitis E virus / hepatitis E / イノシシ … More / ブタ / HEV抗体 / 人獣共通感染症 / E型肝炎 / 培養細胞 / 中和抗体 / ワクチン … More
Except Principal Investigator
E型肝炎ウイルス / TTV / 劇症肝炎 / transfection / tandem dimer / mRNA / 複製中間体 / TTウイルス(TTV) / PCR / 遺伝子型 / 放出 / Tsg101 / 放出機構 / 感染性cDNAクローン / Genotype / Food-borne transmission / Infectious source / IgA class anti-HEV / ELISA / Zoonosis / Hepatitis E virus / Hepatitis E / 輸血感染 / IgAクラスHEV抗体 / 核酸診断法 / 感染経路 / 食感染 / 感染源 / IgAクラス抗HEV抗体 / ELISA法 / 人畜共通感染症 / E型肝炎 / liver / replicative intermediate / circular single-stranded DNA virus / 好中球 / Transfection / 転写調節機構 / 培養細胞 / RFLP / 骨髄 / 肝臓 / 肺 / 1本鎖環状DNAウイルス / extrahepatic disease / liver disease / phylogenetic group / genotype / circular single-stranded DNA / TT virus / 遺伝子変異 / TTウイルス抗体 / 塩基配列 / 血清肝炎 / 超可変領域 / DNAウイルス / TTV抗体 / チンパンジー感染実験 / 電子顕微鏡像 / 特発性肺線維症 / TTV DNA量 / 肝外疾患 / 肝疾患 / 分子系統樹 / 環状1本鎖DNA / TTウイルス / エンベロープ / エクソソーム分泌経路 / 出芽 / 多胞体 / エクソソーム / ESCRT機構 / MVB経路 / エンドソーム輸送 / Vps4 / MVB 経路 / 粒子形成 / E 型肝炎ウイルス / MVB sorting / PSAPモチーフ / ORF3蛋白質 / ゲノム変異 / 細胞レセプター候補分子 / 吸着 / 感受性細胞 / 感染性 cDNA クローン / 感染培養系 / ORF2抗原 / 中和抗体 / ORF3抗原 / ORF3欠損変異ウイルス / 蛍光抗体法 / モノクローナル抗体 / 細胞培養 / 分子 Less
  • Research Projects

    (9 results)
  • Research Products

    (69 results)
  • Co-Researchers

    (9 People)
  •  Research on mechanism of hepatitis E virus egress utilizing membrane traffic

    • Principal Investigator
      NAGASHIMA Shigeo
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Jichi Medical University
  •  Studies on the identification and acquisition mechanism ofcell-derived membrane on the surface of hepatitis E virus particles

    • Principal Investigator
      NAGASHIMA Shigeo
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Virology
    • Research Institution
      Jichi Medical University
  •  Research on release mechanism, genome mutations and cellular receptor of hepatitis E virus (HEV) using cell culture systems for HEV

    • Principal Investigator
      OKAMOTO Hiroaki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Jichi Medical University
  •  Characterization of cell culture-generated hepatitis E virus particles:evaluation of neutralizing antibodies-inducing ability as the material of inactivated vaccineproductionPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Masaharu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Jichi Medical University
  •  Characterization of hepatitis E virus (HEV) particles and analysis of replication mechanism by using a cell culture system for HEV

    • Principal Investigator
      OKAMOTO Hiroaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Jichi Medical University
  •  Investigation of zoonotic infection of hepatitis E virus among mammalians and birdsPrincipal Investigator

    • Principal Investigator
      TAKAHASHI Masaharu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Jichi Medical University
  •  Molecular epidemiological analysis of hepatitis E as a zoonosis and investigation toward its prevention

    • Principal Investigator
      OKAMOTO Hiroaki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      JICHI MEDICAL SCHOOL
  •  Analysis of replication and transcription mechanisms in a newly discovered circular, single-stranded DNA virus (TTV)

    • Principal Investigator
      OKAMOTO Hiroaki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Jichi Medical University
  •  Research on genomic characteristics and disease associations of a newly discovered human serum hepatitis virus (TT virus)

    • Principal Investigator
      MAYUMI Makoto
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Virology
    • Research Institution
      JICHI MEDICAL SCHOOL

All 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book

  • [Book] 肝・胆道系症候群(第2版)その他の肝・胆道系疾患を含めてI肝臓編(上)2010

    • Author(s)
      高橋雅春(共著)
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Book] 肝・胆道系症候群(第2版)その他の肝・胆道系疾患を含めてI肝臓編(上)2010

    • Author(s)
      高橋雅春(共著)
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Book] 肝・胆道系症候群(第2版)I 肝臓編(上) E型肝炎2010

    • Author(s)
      高橋雅春, 岡本宏明
    • Total Pages
      600
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Journal Article] Rat hepatitis E virus derived from wild rats (Rattus rattus) propagates efficiently in human hepatoma cell lines2014

    • Author(s)
      Jirintai S, Tanggis, Mulyanto, Suparyatmo JB, Takahashi M, Kobayashi T, Nagashima S, Nishizawa T, Okamoto H
    • Journal Title

      Virus Research

      Volume: 185 Pages: 92-102

    • DOI

      10.1016/j.virusres.2014.03.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860343, KAKENHI-PROJECT-25860344
  • [Journal Article] Hepatitis E virus egress depends on the exosomal pathway, with secretory exosomes derived from multivesicular bodies2014

    • Author(s)
      Nagashima S, Jirintai S, Takahashi M, Kobayashi T, Tanggis, Nishizawa T, Kouki T, Yashiro T, Okamoto H
    • Journal Title

      Journal of General Virology

      Volume: 95 Issue: 10 Pages: 2166-2175

    • DOI

      10.1099/vir.0.066910-0

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25860343, KAKENHI-PROJECT-25860344
  • [Journal Article] Molecular characterization of a novel hepatitis E virus (HEV) strain obtained from a wild boar in Japan that is highly divergent from the previously recognized HEV strains2014

    • Author(s)
      Takahashi M, Nishizawa T, Nagashima S, Jirintai S, Kawakami M, Sonoda Y, Suzuki T, Yamamoto S, Shigemoto K, Ashida K, Sato Y, Okamoto H
    • Journal Title

      Virus Research

      Volume: 180 Pages: 59-69

    • DOI

      10.1016/j.virusres.2013.12.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860343
  • [Journal Article] Marked genomic heterogeneity of rat hepatitis E virus strains in Indonesia demonstrated on a full-length genome analysis2014

    • Author(s)
      Mulyanto, Suparyatmo JB, Andayani IG, Khalid, Takahashi M, Ohnishi H, Jirintai S, Nagashima S, Nishizawa T, Okamoto H
    • Journal Title

      Virus Research

      Volume: 179 Pages: 102-112

    • DOI

      10.1016/j.virusres.2013.10.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860343
  • [Journal Article] The membrane on the surface of hepatitis E virus particles is derived from the intracellular membrane and contains trans-Golgi network protein 22014

    • Author(s)
      Nagashima S, Takahashi M, Jirintai S, Tanggis, Kobayashi T, Nishizawa T, Okamoto H
    • Journal Title

      Archives of Virology

      Volume: 159 Issue: 5 Pages: 979-991

    • DOI

      10.1007/s00705-013-1912-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860343, KAKENHI-PROJECT-25860344
  • [Journal Article] Characterization of sporadic acute hepatitis E and comparison of hepatitis E virus genomes in acute hepatitis patients and pig liver sold as food in Mie, Japan2014

    • Author(s)
      Okano H, Takahashi M, Isono Y, Tanaka H, Nakano T, Oya Y, Sugimoto K, Ito K, Ohmori S, Maegawa T, Kobayashi M, Nagashima S, Nishizawa T, Okamoto H
    • Journal Title

      Hepatology Research

      Volume: 印刷中 Issue: 10

    • DOI

      10.1111/hepr.12216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860343
  • [Journal Article] Frequent detection and characterization of hepatitis E virus variants in wild rats (Rattus rattus) in Indonesia2013

    • Author(s)
      Mulyanto
    • Journal Title

      Archives of Virology

      Volume: 158 Issue: 1 Pages: 87-96

    • DOI

      10.1007/s00705-012-1462-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-22590419, KAKENHI-PROJECT-23790508
  • [Journal Article] Features of hepatitis E virus infection in humans and animals in Japan2013

    • Author(s)
      Takahashi M, Okamoto H
    • Journal Title

      Hepatol Res

      Volume: 44 Issue: 1 Pages: 43-58

    • DOI

      10.1111/hepr.12175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Frequent detection and characterization of hepatitis E virus variants in wild rats (Rattus rattus) in Indonesia2013

    • Author(s)
      Mulyanto, Depamede SN, Sriasih M, Takahashi M, Nagashima S, Jirintai S, Nishizawa T, Okamoto H
    • Journal Title

      Arch Virol

      Volume: 158(1) Pages: 87-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] strains isolated from an acute hepatitis patient and a wild boar in Mie, Japan2013

    • Journal Title

      Hepatol Res

      Volume: 印刷中 Issue: 6 Pages: 694-699

    • DOI

      10.1111/hepr.12155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-25860343
  • [Journal Article] A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus (HEV) strains : demonstration of HEV infectivity of porcine liver sold as food2012

    • Author(s)
      Takahashi H
    • Journal Title

      Archives of Virology

      Volume: 157 Issue: 2 Pages: 235-246

    • DOI

      10.1007/s00705-011-1153-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-22590419, KAKENHI-PROJECT-23790508
  • [Journal Article] A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus (HEV) strains: demonstration of HEV infectivity of porcine liver sold as food2012

    • Author(s)
      Takahashi H, Tanaka T, Jirintai S, Nagashima S, Takahashi M, Nishizawa T, Mizuo H, Yazaki Y, Okamoto H
    • Journal Title

      Arch Virol

      Volume: 157(2) Pages: 235-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] New findings regarding the epidemic history and population dynamics of Japan-indigenous genotype 3 hepatitis E virus inferred by molecular evolution2012

    • Author(s)
      Nakano T, Takahashi K, Pybus OG, Hashimoto N, Kato H, Okano H, Kobayashi M, Fujita N, Shiraki K, Takei Y, Ayada M, Arai M, Okamoto H, Mishiro S.
    • Journal Title

      Liver Int

      Volume: 32(4) Pages: 675-88

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Molecular analysis of hepatitis E virus from farm rabbits in Inner Mongolia, China and its successful propagation in A549 and PLC/PRF/5 cells2012

    • Author(s)
      D, Mulyanto, Takahashi M, Nagashima S, Kobayashi T, Nishizawa T, Okamoto H
    • Journal Title

      Virus Res

      Volume: 170(1-2) Pages: 126-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Icteric acute hepatitis E with no response of immunoglobulin M class anti-hepatitis E virus antibody2012

    • Author(s)
      Takikawa Y
    • Journal Title

      Hepatology Research

      Volume: 42 Issue: 11 Pages: 1146-1149

    • DOI

      10.1111/j.1872-034x.2012.01023.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-22590419
  • [Journal Article] Molecular epidemiology and genetic history of European-type genotype 3 hepatitis E virus indigenized in the central region of Japan2012

    • Author(s)
      Nakano T, Okano H, Kobayashi M, Ito K, Ohmori S, Nomura T, Kato H, Ayada M, Nakano Y, Akachi S, Sugimoto K, Fujita N, Shiraki K, Takei Y, Takahashi M, Okamoto H
    • Journal Title

      Infect Genet Evol

      Volume: 12(7) Pages: 1524-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Molecular analysis of hepatitis E virus from farm rabbits in Inner Mongolia, China and its successful propagation in A549 and PLC/PRF/5 cells2012

    • Author(s)
      Jirintai S
    • Journal Title

      Virus Research

      Volume: 170 Issue: 1-2 Pages: 126-137

    • DOI

      10.1016/j.virusres.2012.09.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-22590419, KAKENHI-PROJECT-23790508
  • [Journal Article] Molecular epidemiology and genetic history of European-type genotype 3 hepatitis E virus indigenized in the central region of Japan2012

    • Author(s)
      Nakano T
    • Journal Title

      Infection, Genetics and Evolution

      Volume: 12 Issue: 7 Pages: 1524-1534

    • DOI

      10.1016/j.meegid.2012.06.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-22590419
  • [Journal Article] Icteric acute hepatitis E with no response of immunoglobulin M class anti-hepatitis E virus antibody2012

    • Author(s)
      Takikawa Y, Miyamoto Y, Onodera M, Kuroda H, Kasai K, Miyasaka A, Takahashi M, Okamoto H, Suzuki K
    • Journal Title

      Hepatol Res

      Volume: 42(11) Pages: 1146-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype2011

    • Author(s)
      Takahashi M
    • Journal Title

      Journal of General Virology

      Volume: 92 Issue: 4 Pages: 902-908

    • DOI

      10.1099/vir.0.029470-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-22590419
  • [Journal Article] Tumour susceptibility gene 101 and the vacuolar protein sorting pathway are required for the release of hepatitis E virions2011

    • Author(s)
      Nagashima S
    • Journal Title

      Journal of General Virology

      Volume: 92 Issue: 12 Pages: 2838-2848

    • DOI

      10.1099/vir.0.035378-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-22590419, KAKENHI-PROJECT-23790508
  • [Journal Article] A nationwide survey of hepatitis E virus (HEV) infection in wild boars in Japan: identification of boar HEV strains of genotypes 3 and 4 and unrecognized genotypes2011

    • Author(s)
      Sato Y, Sato H, Naka K, Furuya S, Tsukiji H, Kitagawa K, Sonoda Y, Usui T, Sakamoto H, Yoshino S, Shimizu Y, Takahashi M, Nagashima S, Jirintai, Nishizawa T, Okamoto H.
    • Journal Title

      Arch Virol

      Volume: 156(8) Pages: 1345-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype2011

    • Author(s)
      Takahashi M, Nishizawa T, Sato H, Sato Y, Jirintai, Nagashima S, Okamoto H
    • Journal Title

      J Gen Virol

      Volume: 92(Pt 4) Pages: 902-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] 北海道東部の釧路市および根室市におけるE型肝炎ウイルス感染の疫学調査:感染の地域差と食文化の相違について2011

    • Author(s)
      田辺利男, 水尾仁志, 矢崎康幸, 高橋雅春, 岡本宏明
    • Journal Title

      肝臓

      Volume: 52 Pages: 567-574

    • NAID

      10029688070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Journal Article] Tumour susceptibility gene 101 and the vacuolar protein sorting pathway are required for the release of hepatitis E virions.2011

    • Author(s)
      Nagashima S, Takahashi M, Jirintai S, Tanaka T, Nishizawa T, Yasuda J, Okamoto H.
    • Journal Title

      J Gen Virol

      Volume: 92(Pt 12) Pages: 2838-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] A PSAPmotif in the ORF3 protein of hepatitis E virusis necessary for virion release from infectedcells2011

    • Author(s)
      Nagashima S, Takahashi M, Jirintai, Tanaka T,Yamada K, Nishizawa T, Okamoto H
    • Journal Title

      J Gen Virol

      Volume: 92 Issue: 2 Pages: 269-278

    • DOI

      10.1099/vir.0.025791-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Journal Article] Analysis of the full-length genome of a hepatitis E virus isolate obtained from a wild boar in Japan that is classifiable into a novel genotype.2011

    • Author(s)
      Takahashi M
    • Journal Title

      Journal of General Virology

      Volume: 92 Pages: 902-908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Journal Article] A PSAP motif in the ORF3 protein of hepatitis E virus is necessary for virion release from infected cells2011

    • Author(s)
      Nagashima S, Takahashi M, Jirintai, Tanaka T, Yamada K, Nishizawa T, Okamoto H
    • Journal Title

      J Gen Virol

      Volume: 92(Pt 2) Pages: 269-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] A nationwide survey of hepatitis E virus (HEV) infection in wild boars in Japan : identification of boar HEV strains of genotypes 3 and 4 and unrecognized genotypes2011

    • Author(s)
      Sato Y
    • Journal Title

      Archives of Virology

      Volume: 156 Issue: 8 Pages: 1345-1358

    • DOI

      10.1007/s00705-011-0988-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090, KAKENHI-PROJECT-22590419
  • [Journal Article] Hepatitis E Virus(REV)strains in serum samples can replicate efficiently incultured cells despite the coexistence of HEV antibodies : characterization of HEV virions in blood circulation.2010

    • Author(s)
      Takahashi M
    • Journal Title

      Journal of Clinical Microbiology

      Volume: 48 Pages: 1112-1125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] A nationwide survey of hepatitis E virus infection in the general population of Japan2010

    • Author(s)
      Takahashi M, Tamura K, Hoshino Y, Nagashima S, Yazaki Y, Mizuo H, Iwamoto S, Okayama M, Nakamura Y, Kajii E, Okamoto H.
    • Journal Title

      J Med Virol

      Volume: 82(2) Pages: 271-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Hepatitis E Virus (HEV) strains in serum samples can replicate efficiently in cultured cells despite the coexistence of HEV antibodies: characterization of HEV virions in blood circulation2010

    • Author(s)
      Takahashi M, Tanaka T, Takahashi H, Hoshino Y, Nagashima S, Jirintai, Mizuo H, Yazaki Y, Takagi T, Azuma M, Kusano E, Isoda N, Sugano K, Okamoto H.
    • Journal Title

      J Clin Microbiol

      Volume: 48(4) Pages: 1112-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Hepatitis E virus (HEV) strains in serum samples can replicate efficiently in cultured cell despite the coexistence of HEV antibodies : characterization of HEV virions in blood circulation.2010

    • Author(s)
      Takahashi M
    • Journal Title

      Journal of Clinical Microbiology

      Volume: 48 Pages: 1112-1125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Journal Article] Hepatitis Evirus (HEV) strains in serum samples canreplicate efficiently in cultured cells despitethe coexistence of HEV antibodies:characterization of HEV virions in bloodcirculation.2010

    • Author(s)
      Takahashi M, Tanaka T, Takahashi H,Hoshino Y, Nagashima S, Jirintai, Mizuo H,Yazaki Y, Takagi T, Azuma M, Kusano E,Isoda N, Sugano K, Okamoto H
    • Journal Title

      J Clin Microbiol

      Volume: 48 Issue: 4 Pages: 1112-1125

    • DOI

      10.1128/jcm.02002-09

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Journal Article] 札幌圏内小流行4 型HEV株が検出された茨城県内E型肝炎の1例2010

    • Author(s)
      相川達也, 池澤和人, 間宮孝, 上野ちさと, 和田由美子, 島田沙香, 津田文男, 高橋雅春, 岡本宏明
    • Journal Title

      肝臓

      Volume: 51 Pages: 579-581

    • NAID

      10027469901

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Journal Article] Molecular and serological survey of hepatitis E virus infection among domestic pigs in Inner Mongolia2010

    • Author(s)
      Jinshan, Jirintai, Manglai D, Takahashi M, Nagashima S, Okamoto H
    • Journal Title

      China. Arch Virol

      Volume: 155(8) Pages: 1217-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Journal Article] Molecular andserological survey of hepatitis E virusinfection among domestic pigs in InnerMongolia2010

    • Author(s)
      Jinshan, Jirintai, Manglai D, Takahashi M,Nagashima S, Okamoto H
    • Journal Title

      China. Arch Virol

      Volume: 155 Issue: 8 Pages: 1217-1226

    • DOI

      10.1007/s00705-010-0706-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590419
  • [Journal Article] ORF3 protein of hepatitis E virus is essential for virion release from infected cells.2009

    • Author(s)
      Yamada K, Takahashi M, Hoshino Y, Takahashi H, Ichiyama K, Tanaka T, Okamoto H
    • Journal Title

      J Gen Virol doi:10.1099/Vir.0.010561-0(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Sporadic acute hepatitis E occurred constantly during the last decade in northeast Japan.2009

    • Author(s)
      Inoue J, Ueno Y, Nagasaki F, Akahane T, Fukushima K, Kogure T, Kondo Y, Kakazu E, Tamai K, Kido O, Nakagome Y, Ninomiya M, Obara N, Wakui Y, Takahashi M, Okamoto H, Shimosegawa T
    • Journal Title

      J Gastroenterol 44

      Pages: 329-337

    • NAID

      10025174367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Development and characterization of a genotype 4 hepatitis E virus cell culture system using the HE-JF5/15F strain recovered from a fulminant hepatitis patient.2009

    • Author(s)
      Tanaka T, Takahashi M, Takahashi H, Ichiyama K, Hoshino Y, Nagashima S, Mizuo H, Okamoto H
    • Journal Title

      J Clin Microbiol 47

      Pages: 1906-1910

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Construction of an infectious cDNA clone of hepatitis E virus strain JE03-1760F that can propagate efficiently in cultured cells.2009

    • Author(s)
      Yamada K, Takahashi M, Hoshino Y, Takahashi H, Ichiyama K, Tanaka T, Okamoto H
    • Journal Title

      J Gen Virol 90(2)

      Pages: 457-462

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Production of monoclonal antibodies against hepatitis E virus capsid protein and evaluation of their neutralizing activity in a cell culture system.2008

    • Author(s)
      Takahashi M, Hoshino Y, Tanaka T, Takahashi H, Nishizawa T, Okamoto H
    • Journal Title

      Arch Virol 153

      Pages: 657-666

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Monoclonal antibodies raised against the ORF3 protein of hepatitis E virus (HEV) can capture HEV particles in culture supernatant and serum but not those in feces.2008

    • Author(s)
      Takahashi M, Yamada K, Hoshino Y, Takahashi H, Ichiyama K, Tanaka T, Okamoto H
    • Journal Title

      Arch Virol 153

      Pages: 1703-1713

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Monoclonal antibodies raised against the 0RF3 protein of hepatitis E virus (HEV) can capture HEV particles in culture supernatant and serum but not those in feces.2008

    • Author(s)
      Takahashi M
    • Journal Title

      Archives of Virology 153

      Pages: 1703-1713

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Mutational events during the primary propagation and consecutive passages of hepatitis E virus strain JE03-1760F in cell culture.2008

    • Author(s)
      Lorenzo FR, Tanaka T, Takahashi H, Ichiyama K, Hoshino Y, Yamada K, Inoue J, Takahashi M, Okamoto H
    • Journal Title

      Virus Res 137

      Pages: 86-96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Development and evaluation of an efficient cell-culture system for Hepatitis E virus.2007

    • Author(s)
      Tanaka T, Takahashi M, Kusano E, Okamoto H.
    • Journal Title

      J Gen Virol 88

      Pages: 903-911

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Prolonged fecal shedding of hepatitis E virus (HEV) during sporadic acute hepatitis E: evaluation of infectivity of HEV in fecal specimens in a cell culture system.2007

    • Author(s)
      Takahashi M, Tanaka T, Azuma M, Kusano E, Aikawa T, Shibayama T, Yazaki Y, Mizuo H, Inoue J, Okamoto H
    • Journal Title

      J Clin Microbiol 45(11)

      Pages: 3671-3679

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Analysis of the full-length genome of hepatitis E virus isolates obtained from farm pigs in Mongolia.2007

    • Author(s)
      Lorenzo FR, Tsatsralt-Od B, Ganbat S, Takahashi M, Okamoto H
    • Journal Title

      J Med Virol 79

      Pages: 1128-1137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Identification of genotype 4 hepatitis E virus strains from a patient with acute hepatitis E and farm pigs in Bali, Indonesia.2007

    • Author(s)
      Wibawa IDN, Suryadarma IGA, Mulyanto, Tsuda F, Matsumoto Y, Ninomiya M, Takahashi M, Okamoto H
    • Journal Title

      J Med Virol 79

      Pages: 1138-1146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Prolonged fecal shedding of hepatitis E virus(HEV)druing sporadic acute hepatitis E:evaluation of infectivity of HEV in fecal specimens in a cell culture system.2007

    • Author(s)
      Takahashi M
    • Journal Title

      Journal of Clinical Microbiology 45

      Pages: 3671-3679

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Ongoing subclinical infection of hepatitis E virus among blood donors with an elevated alanine aminotransferase level in Japan.2007

    • Author(s)
      Gotanda Y, Iwata A, Ohnuma H, Yoshikawa A, Mizoguchi H, Endo K, Takahashi M, Okamoto H
    • Journal Title

      J Med Virol 79

      Pages: 734-742

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Unchanged high prevalence of antibodies to hepatitis E virus (HEV) and HEV RNA among blood donors with an elevated alanine aminotransferase level in Japan during 1991-2006.2007

    • Author(s)
      Fukuda S, Ishikawa M, Ochiai N, Suzuki Y, Sunaga J, Shinohara N, Nozawa K, Tsuda F, Takahashi M, Okamoto H
    • Journal Title

      Arch Virol 152

      Pages: 1623-1635

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390134
  • [Journal Article] Simultaneous detection of immunoglobulin A (IgA) and IgM antibodies against hepatitis E virus (HEV) is highly specific diagnosis of acute HEV infection2005

    • Author(s)
      Takahashi M.
    • Journal Title

      Journal of Clinical Microbiology 43

      Pages: 49-56

    • Data Source
      KAKENHI-PROJECT-16390137
  • [Journal Article] Correlation between positivity for immunoglobulin A antibodies and viraemia of swine hepatitis E virus observed among farm pigs in Japan2005

    • Author(s)
      Takahashi M.
    • Journal Title

      Journal of General Virology 86-6

      Pages: 1807-1813

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590421
  • [Journal Article] Simultaneous detection of immunoglobulin A (IgA) and IgM antibodes against hepatitis E virus (HEV) is highly specific for diagnosis of acute HEV infection2005

    • Author(s)
      Takahashi M
    • Journal Title

      Journal of Clinical Microbiology 43

      Pages: 49-56

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390137
  • [Journal Article] Simultaneous detection of immunoglobulin A (IgA) and IgM antibodies against hepatitis E virus (HEV) is highly specific for diagnosis of acute HEV infection.2005

    • Author(s)
      Takahashi M, et al.
    • Journal Title

      J Clin Microbiol 43

      Pages: 49-56

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390137
  • [Journal Article] Correlation between positivity for immunoglobulin A antibodies and viraemia of swine hepatitis E virus observed among farm pigs in Japan.2005

    • Author(s)
      Takahashi M.
    • Journal Title

      Journal of General Virology 86・6

      Pages: 1807-1813

    • Data Source
      KAKENHI-PROJECT-16390137
  • [Journal Article] Correlation between positivity for immunoglobulin A antibodies and viraemia of swine hepatitis E virus observed among farm pigs in Japan2005

    • Author(s)
      Takahashi M.
    • Journal Title

      Journal of General Virology 86・6

      Pages: 1807-1813

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590421
  • [Journal Article] Simultaneous detection of immunoglobulin A (IgA) and IgM antibodies against hepatitis E virus (HEV) is highly specific for diagnosis of acute HEV infection2005

    • Author(s)
      Takahashi M.
    • Journal Title

      Journal of Clinical Microbiology 43・1

      Pages: 49-56

    • Data Source
      KAKENHI-PROJECT-17590421
  • [Journal Article] A high genomic similarity between European type hepatitis E virus subgenotype 3e Jirintai S, Jinshan, Tanggis, Manglai 18. strains isolated from an acute hepatitis patient and a wild boar in Mie, Japan

    • Author(s)
      Okano H, Nakano T, Sugimoto K, Takahashi K, Nagashima S, Takahashi M, Arai M, Okamoto H
    • Journal Title

      Jinshan, Tanggis, Manglai

    • Data Source
      KAKENHI-PROJECT-22390090
  • [Presentation] 細胞内膜輸送系を利用したE型肝炎ウイルスの放出機構の解析2013

    • Author(s)
      長嶋 茂雄、高橋 雅春、吉林台、小林 富成、西澤 勉、岡本 宏明
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-25860343
  • [Presentation] 培養細胞から放出された E 型肝炎ウイルスの粒子表面に存在する膜成分の抗原性の解析2012

    • Author(s)
      長嶋茂雄、高橋雅春、吉林台、西澤勉、小林富成、岡本宏明
    • Organizer
      第60回日本ウイルス学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2012-11-14
    • Data Source
      KAKENHI-PROJECT-23790508
  • [Presentation] Tsg101 and the vacuolar protein sorting pathway are required for virion release of hepatitis E virus2011

    • Author(s)
      Nagashima S, Takahashi M, Jirintai, Tanaka T, Nishizawa T, Yasuda J, Okamoto H
    • Organizer
      15thInternational Congress of Virology (第59回日本ウイルス学会学術集会)
    • Place of Presentation
      札幌
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-23790508
  • [Presentation] Tsg101 and the vacuolar protein sorting pathway are required for virion release of hepatitis E virus.2011

    • Author(s)
      Nagashima S, Takahashi M, Jirintai, Tanaka T, Nishizawa T, Yasuda J, Okamoto H.
    • Organizer
      15th International Congress of Virology (第59回日本ウイルス学会学術集会)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23790508
  • [Presentation] Tsg101 and vacuolar protein sorting pathway are required for virion release of hepatitis E virus2011

    • Author(s)
      Nagashima, S., Takahashi, M., Jirintai, Tanaka, T., Nishizawa, T., Yasuda J, Okamoto, H
    • Organizer
      XV International Congress of Virology
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-22390090
  • [Presentation] E型肝炎ウイルスの細胞侵入機構の解析

    • Author(s)
      長嶋茂雄、吉林台、小林富成、唐吉思、高橋雅春、西澤勉、岡本宏明
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜 (パシフィコ横浜)
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-25860343
  • 1.  OKAMOTO Hiroaki (30177092)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 40 results
  • 2.  NISHIZAWA Tsutomu (30306112)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 3.  NAGASHIMA Shigeo (60433116)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 24 results
  • 4.  KOBAYASHI Tominari (00634164)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 10 results
  • 5.  TANAKA Toshinori (30146154)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 6.  YASUDA Jiro (10282518)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  YASHIRO Takashi (80119859)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  KOUKI Tom (70350436)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  MAYUMI Makoto (00049016)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi