Koshikawa Naohiko 越川直彦

… Alternative Names

KOSIKAWA Naohiko 越川直彦

KOSHIKAWA Naohiko 越川直彦

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Researcher Number	70334282
Other IDs
Affiliation (Current)	2025: 東京科学大学, 生命理工学院, 教授 2025: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所, 部長
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 生命理工学院, 教授 2020 – 2023: 東京工業大学, 生命理工学院, 教授 2016 – 2020: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所, 部長 2016: 神奈川県立がんセンター臨床研究所, がん生物学部, 部長 2015 – 2016: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), 臨床研究所がん生物学部, 部長 … More 2015: 地方独立行政法人神奈川県立病院機構神奈川県立がんセンター(臨床研究所), その他部局等, 部長 2015: 東京大学, 医科学研究所, 准教授 2010 – 2013: 東京大学, 医科学研究所, 准教授 2010: 東京大学, 医科学研究所, 助教 2008 – 2009: 東京大学, 医科学研究所, 講師 2006: 東京大学, 医科学研究所, 助教 2003 – 2006: 東京大学, 医科学研究所, 助手 Less
Review Section/Research Field	Principal Investigator Urology / Basic Section 49030:Experimental pathology-related / Basic Section 57020:Oral pathobiological science-related / Complex systems / Laboratory medicine / Experimental pathology / Biological Sciences / General medical chemistry Except Principal Investigator Complex systems / Dermatology … More / Basic Section 90130:Medical systems-related / Tumor biology / Mathematical Sciences in Search of New Cooperation / Tumor biology / Experimental pathology / Biological Sciences Less
Keywords	Principal Investigator HB-EGF / 細胞外マトリックス / MT1-MMP / 癌 / 診断 / プロセシング / 上皮組織 / Heparin-binding domain / EGF-R / バイオマーカー … More / がん / ラミニン / 膀胱がん / 扁平上皮がん細胞 / トタンスジェニックマウス / がん細胞パネル / 発癌 / 頭頸部癌 / 融合遺伝子 / ラミニン融合遺伝子 / 浸潤・転移 / 口腔癌 / 増殖・分化 / 扁平上皮 / 扁平上皮細胞 / 基底膜 / 生体機能利用 / 発生・分化 / プロテオーム / 細胞・組織 / 生体組織の構築と破綻 / 時系列画像データ / 多次元時系列データ / 逆相蛋白質アレイ（RPPA) / 間葉上皮移行(MET) / 上皮間葉移行（EMT） / 逆走蛋白質アレイ / 数理腫瘍学 / 上皮細胞 / 混合正規分布 / 層別化解析 / 数理モデル、 / 逆相タンパク質アレイ / プロテオミクス / チロシンキナーゼ受容体 / RPPA / シミュレーション / 上皮間葉転換（EMT） / 層化解析 / 数理モデル、シミュレーション / EMT / 受容体チロシンキナーゼ / 悪性化進展シグナル / 肝がん / 上皮間葉転換 / 肝がん幹細胞 / 生物統計 / 悪性化進展 / 数理シミュレーション / 数理モデル / 逆相タンパク質アレイ（RPPA） / 細胞シグナル / 幹細胞性 / 肝細胞がん / 膵臓癌 / がん化促進因子 / ErbB受容体リガンド / プロセシング断片 / 限定分解（プロセシング） / 基質 / 膜型メタロプロテアーゼ / 膜蛋白質 / EphA2 / 膵癌 / MS / プロテオリシス / トランスレーショナルリサーチ / 治療奏効 / 受容体型チロシンキナーゼ / シグナル伝達 / 膜型MMP / EphA / 予後マーカー / 診断マーカー / 尿 / 尿路がん / 腫瘍マーカー / 擬似血管新生 / EGF様ドメイン / EGF受容体 / ラミニン5 / ラミニンγ2鎖 / 細胞外マトリック / MMP … More Except Principal Investigator 遺伝子 / Mint3 / HIF-1 / MT1-MMP / 浸潤 / 再生医療 / 臨床 / 細胞・組織 / 癌 / 色素異常症 / 浸潤・転移 / がん / コラーゲン / 腫瘍形成 / FIH-1 / 大腸がん / RPPA / 逆相タンパク質アレイ / バイオバンク / 悪性化 / 肝臓 / 浸潤転移 / 膜型マトリックスメタロプロテアーゼ / Invasion / HIF / EphA2 / がん微小環境 / ラミニン / 肝細胞がん / CD90 / EpCAM / がんの増殖・浸潤・転移 / がん幹細胞 / 肝臓がん / 病理学 / 分子標的治療 / 数理科学 / ｃ－ＫＩＴ / SH3ドメイン / KIT / 悪性黒色腫 / 電子顕微鏡 / メラノサイト / リン酸化酵素 / 全エクソームシーケンス法 / c-kit / 病因遺伝子同定 / 全エクソームシークエンス / 遺伝性皮膚疾患 / 常染色体優性遺伝形式 / 遺伝性全身性メラニン色素異常症 / 動的平衡 / 細胞内信号伝達 / 薬剤耐性 / 骨代謝 / 細胞膜分子 / ECM分解 / 細胞接着 / 細胞分子動態 / 数理モデリング / 数理腫瘍学 / HIH-1 / p27RF-Rho / ZF21 / 細胞運動 / リン酸化 / 増殖 / がん細胞 / HB-EGF / プロテアーゼ / 転移 / マトリックス・メタロプロテアーゼ / 腫瘍 / CD44 / MMP / 腫瘍抑制 / MMP-2 / コラーゲン分解 / 生モノクローナル抗体 / 腫瘍血管新 / ラミニン332 / マクロファージ / 浸潤突起 / Rho活性化 / p27RE-Rho / 腫瘍微小環境 / 膜型プロテアーゼ Less

スプライシング異常が誘発する上皮発がんの新たな分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  越川直彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Institute of Science Tokyo
Integrated analysis and regulation of cellular diversity
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Japanese Foundation for Cancer Research
Analysis of the molecular mechanism for collective invasion of squamous cell carcinoma by novel laminin fusion genePrincipal Investigator
- Principal Investigator
  
  Koshikawa Naohiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Tokyo Institute of Technology
バイオバンクの効果的な利用に向けた品質予測法の開発
- Principal Investigator
  
  室井敦
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Kanagawa Cancer Center Research Institute
Analysis of cleavage fragments produced by proteolysis on cancer cell membranePrincipal Investigator
- Principal Investigator
  
  KOSHIKAWA NAOHIKO
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kanagawa Cancer Center Research Institute
Integrated analysis and regulation of cellular diversity
- Principal Investigator
  
  FUJITA Naoya
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Japanese Foundation for Cancer Research
Analysis of the molecular mechanism for formation and breakdown of biotissues by mathematical modelingPrincipal Investigator
- Principal Investigator
  
  Koshikawa Naohiko
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Institute of Technology
  Kanagawa Cancer Center Research Institute
Analysis of MT1-MMP-dependent molecular pathways in the diversity and transformation of hepatocellular carcinoma
- Principal Investigator
  
  Seiki Motoharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kanazawa University
細胞膜分子動態数理モデリングによるがん悪性化メカニズムの解明
- Principal Investigator
  
  鈴木貴
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Mathematical Sciences in Search of New Cooperation
- Research Institution
  Osaka University
Identification of novel therapeutic target of melanoma with focus on gain-of-function mutation of SH3 domain of KIT
- Principal Investigator
  
  SUGIURA Kazumitsu
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Fujita Health University
  Nagoya University
Elucidation of pathogenesis of universal inherited melanodyschromatosis
- Principal Investigator
  
  SUGIURA Kazumitsu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Nagoya University
Development of a novel diagnostic method for bladder cancerPrincipal Investigator
- Principal Investigator
  
  Koshikawa Naohiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kanagawa Cancer Center Research Institute
  The University of Tokyo
増殖因子および受容体の蛋白質プロセッシングによる制御システムの解析Principal Investigator
- Principal Investigator
  
  越川直彦
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Study of MT1-MMP in cancer
- Principal Investigator
  
  SEIKI Motoharu
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
Laminin-like molecule is a potent therapeutic and diagnostic target for bladder cancer.Principal Investigator
- Principal Investigator
  
  KOSHIKAWA Naohiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  The University of Tokyo
Analysis of mechanisms involved in multifunction of tumor invasion factor emmprin
- Principal Investigator
  
  NABESHIMA Kazuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Fukuoka University
Tumor-stroma interaction mediated by proteases
- Principal Investigator
  
  SEIKI Motoharu
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis of novel substrate for MT1-MMP and its cellular functionsPrincipal Investigator
- Principal Investigator
  
  KOSHIKAWA Naohiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
膜型メタロプロテアーゼによる細胞外基質分解と細胞機能制御に関する研究Principal Investigator
- Principal Investigator
  
  越川直彦
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo

[Book] 膜タンパク質工学ハンドブック2020
- Author(s)
  室井　敦、星野大輔、清木元治、越川直彦
- Total Pages
  7
- Publisher
  エヌ・ティー・エス
- Data Source
  KAKENHI-PLANNED-17H06329
[Journal Article] EphA2 Proteolytic Fragment as a Sensitive Diagnostic Biomarker for Very Early-stage Pancreatic Ductal Carcinoma2023
- Author(s)
  Sato Shinya、Nakagawa Masatoshi、Terashima Takeshi、Morinaga Soichiro、Miyagi Yohei、Yoshida Eisaku、Yoshimura Toru、Seiki Motoharu、Kaneko Shuichi、Ueno Makoto、Yamashita Taro、Koshikawa Naohiko
- Journal Title
  
  Cancer Research Communications
  
  Volume: 3 Issue: 9 Pages: 1862-1874
- DOI
  10.1158/2767-9764.crc-23-0087
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16984, KAKENHI-PROJECT-23K08708, KAKENHI-PROJECT-21K09840, KAKENHI-PROJECT-22H04923
[Journal Article] A novel diagnostic and predictive biomarker for the development of liver cancer and extrahepatic metastasis using the serum laminin γ2 monomer2023
- Author(s)
  Kaneko Ryo、Funahashi Nobuaki、Yoshimura Toru、Yamashita Taro、Koshikawa Naohiko
- Journal Title
  
  Electrophoresis Letters
  
  Volume: 67 Issue: 2 Pages: 59-64
- DOI
  10.2198/electroph.67.59
- ISSN
  2189-2628, 2189-2636
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10865, KAKENHI-PROJECT-21K09840
[Journal Article] ラミニン γ2 単鎖をバイオマーカーとした肝発がん、遠隔転移の予測を可能とする新たな診断法の構築2023
- Author(s)
  兼子崚、舟橋伸昭、吉村徹、山下太郎、越川直彦
- Journal Title
  
  電気泳動
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09840
[Journal Article] Chronological change in EPHA2 protein expression Is associated with recurrence of bladder cancer.2022
- Author(s)
  Koizumi M, Sato S, Yoshihara M, Nakamura Y, Terao H, Okubo Y, Washimi K, Yoshioka E, Yokose T, Kishida T, Koshikawa N, Miyagi Y.
- Journal Title
  
  Anticancer Research
  
  Volume: 12 Pages: 5783-5794
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06329
[Journal Article] Clinical evaluation of urine laminin‐γ2 monomer as a potent biomarker for non‐muscle invasive bladder cancer2022
- Author(s)
  Karashima Takashi、Umemoto Susumu、Kishida Takeshi、Osaka Kimito、Nakagawa Masatoshi、Yoshida Eisaku、Yoshimura Toru、Sakaguchi Masahiko、Nishimoto Hiroyuki、Tai Mami、Inoue Keiji、Seiki Motoharu、Koshikawa Naohiko、Shuin Taro
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 3 Pages: 2453-2462
- DOI
  10.1002/cam4.5087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09840, KAKENHI-PROJECT-22H04923
[Journal Article] Proteolytic cleavage of membrane proteins by <scp>membrane type‐1 MMP</scp> regulates cancer malignant progression2022
- Author(s)
  Ikeda Kazuki、Kaneko Ryo、Tsukamoto Eiki、Funahashi Nobuaki、Koshikawa Naohiko
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 2 Pages: 348-356
- DOI
  10.1111/cas.15638
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11663, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-22H04923
[Journal Article] Expression of Cancer Stem Cell Markers EpCAM and CD90 Is Correlated with Anti- and Pro-Oncogenic EphA2 Signaling in Hepatocellular Carcinoma2021
- Author(s)
  Asakura Nobuhiko、Nakamura Naotoshi、Muroi Atsushi、Nojima Yosui、Yamashita Taro、Kaneko Shuichi、Ikeda Kazuki、Koshikawa Naohiko、Suzuki Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 16 Pages: 8652-8652
- DOI
  10.3390/ijms22168652
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-19H05422, KAKENHI-PLANNED-16H06576, KAKENHI-PROJECT-20K15422, KAKENHI-INTERNATIONAL-16K21739, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-21K09840
[Journal Article] 肝細胞がんのシグナル伝達と生物統計による層別化2021
- Author(s)
  朝倉暢彦、室井　敦、越川直彦、鈴木　貴
- Journal Title
  
  Precision medicine
  
  Volume: 13 Pages: 1224-1230
- Data Source
  KAKENHI-PLANNED-17H06329
[Journal Article] Novel LAMC2 fusion protein has tumor‐promoting properties in ovarian carcinoma2021
- Author(s)
  Daisuke Hoshino、Kato Hisamori、Fukumura Kazuhiro、Mayeda Akila、Miyagi Yohei、Seiki Motoharu、Koshikawa Naohiko
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 12 Pages: 4957-4967
- DOI
  10.1111/cas.15149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07202, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-21K09840
[Journal Article] Serum laminin γ2 monomer as a novel diagnostic and predictive biomarker for hepatocellular carcinoma.2021
- Author(s)
  T Yamashita, N Koshikawa, T Shimakami, T Terashima, M Nakagawa, K Nio, R Horii, N Iida, K Kawaguchi, K Arai, Y Sakai, T Yamashita, E Mizukoshi, M Honda, A Kitao, S Kobayashi, S Takahara, Y Imai, K Yoshimura, T Murayama, Y Nakamoto, E Yoshida, T Yoshimura, M Seiki, S Kaneko.
- Journal Title
  
  Hepatology
  
  Volume: - Issue: 2 Pages: 760-775
- DOI
  10.1002/hep.31758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-18H02792, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-19H03637, KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-17H01886, KAKENHI-PROJECT-21H02900, KAKENHI-PROJECT-20K16984, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-21K09840
[Journal Article] Membrane type 1 matrix metalloproteinase regulates anaplastic thyroid carcinoma cell growth and invasion into the collagen matrix2020
- Author(s)
  Yoshida Tatsuya、Suganuma Nobuyasu、Sato Shinya、Toda Soji、Nakayama Hirotaka、Masudo Katsuhiko、Okubo Yoichiro、Hayashi Hiroyuki、Yokose Tomoyuki、Koshikawa Naohiko、Rino Yasushi、Iwasaki Hiroyuki、Miyagi Yohei、Masuda Munetaka、Hoshino Daisuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 529 Issue: 4 Pages: 1195-1200
- DOI
  10.1016/j.bbrc.2020.06.043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08713, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329
[Journal Article] Evaluation of the RAS signaling network in response to MEK inhibition using organoids derived from a familial adenomatous polyposis patient2020
- Author(s)
  Osumi Hiroki、Muroi Atsushi、Sakahara Mizuho、Kawachi Hiroshi、Okamoto Takuya、Natsume Yasuko、Yamanaka Hitomi、Takano Hiroshi、Kusama Daisuke、Shinozaki Eiji、Ooki Akira、Yamaguchi Kensei、Ueno Masashi、Takeuchi Kengo、Noda Tetsuo、Nagayama Satoshi、Koshikawa Naohiko、Yao Ryoji
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 17455-17455
- DOI
  10.1038/s41598-020-74530-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-18H02684, KAKENHI-PROJECT-19K22570, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329
[Journal Article] Vasoactive Intestinal Peptide Derived From Liver Mesenchymal Cells Mediates Tight Junction Assembly in Mouse Intrahepatic Bile Ducts2020
- Author(s)
  Sato A, Kakinuma S, Miyoshi M, Kamiya A, Tsunoda T, Kaneko S, Tsuchiya J, Shimizu T, Takeichi E, Nitta S, Kawai-Kitahata F, Murakawa M, Itsui Y, Nakagawa M, Azuma S, Koshikawa N, Seiki S, Nakauchi H, Asahina Y, Watanabe M.
- Journal Title
  
  Hepatology Communications
  
  Volume: 4 Issue: 2 Pages: 235-254
- DOI
  10.1002/hep4.1459
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07964, KAKENHI-PROJECT-19K08415, KAKENHI-PROJECT-19K08461, KAKENHI-PROJECT-19K17392, KAKENHI-PROJECT-19K17453, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-18H02790, KAKENHI-PROJECT-17K09406, KAKENHI-PROJECT-17K09407, KAKENHI-PROJECT-17K19647, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027, KAKENHI-PROJECT-19H03635, KAKENHI-PROJECT-19H03643
[Journal Article] NH2‐terminal fragment of ZF21 protein suppresses tumor invasion via inhibiting the interaction of ZF21 with FAK2020
- Author(s)
  Makoto Nagano, Daisuke Hoshino, Jiro Toshima, Motoharu Seiki, Naohiko Koshikawa
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 12 Pages: 4393-4404
- DOI
  10.1111/cas.14665
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06571, KAKENHI-PROJECT-16H06277, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06329
[Journal Article] Unique Biological Activity and Potential Role of Monomeric Laminin-γ2 as a Novel Biomarker for Hepatocellular Carcinoma: A Review2019
- Author(s)
  Yasuda Hiroshi、Nakagawa Masatoshi、Kiyokawa Hirofumi、Yoshida Eisaku、Yoshimura Toru、Koshikawa Naohiko、Itoh Fumio、Seiki Motoharu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 1 Pages: 226-226
- DOI
  10.3390/ijms20010226
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08655, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-16H04695, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027
[Journal Article] Utility of a reverse phase protein array to evaluate multiple biomarkers in diffuse large B‐cell lymphoma2019
- Author(s)
  Suzuki M、Muroi A、Nojima M、Numata A、Takasaki H、Sakai R、Yokose T、Miyagi Y、Koshikawa N.
- Journal Title
  
  Proteomics Clinical Applications
  
  Volume: 14 Issue: 1 Pages: 1900091-1900091
- DOI
  10.1002/prca.201900091
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027
[Journal Article] Identification of Proteolytic Cleavage Sites of EphA2 by Membrane Type 1 Matrix Metalloproteinase on the Surface of Cancer Cells2018
- Author(s)
  Kikuchi K, Kozuka-Hata H, Oyama M, Seiki M, Koshikawa N
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1731 Pages: 29-37
- DOI
  10.1007/978-1-4939-7595-2_3
- ISBN
  9781493975945, 9781493975952
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06578, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-16H04695
[Journal Article] Activated EphA2 processing by MT1-MMP is involved in malignant transformation of ovarian tumours in vivo2018
- Author(s)
  Takahashi Y, Hamasaki M, Aoki M, Koga K, Koshikawa N, Miyamoto S, Nabeshima K.
- Journal Title
  
  Anticancer Res
  
  Volume: 38 Issue: 7 Pages: 4257-4266
- DOI
  10.21873/anticanres.12722
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-16H04695
[Journal Article] Study on the tumor-induced angiogenesis using mathematical models2017
- Author(s)
  Suzuki Takashi、Minerva Dhisa、Nishiyama Koichi、Koshikawa Naohiko、Chaplain Mark Andrew Joseph
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 1 Pages: 15-23
- DOI
  10.1111/cas.13395
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06576, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-26247013, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09027
[Journal Article] Serum monomeric laminin-γ2 as a novel biomarker for hepatocellular carcinoma.2017
- Author(s)
  Kiyokawa H, Yasuda H, Oikawa R, Okuse C, Matsumoto N, Ikeda H, Watanabe T, Yamamoto H, Itoh F, Otsubo T, Yoshimura T, Yoshida E, Nakagawa M, Koshikawa N, Seiki M.
- Journal Title
  
  Cancer Science
  
  Volume: 108 Issue: 7 Pages: 1432-1439
- DOI
  10.1111/cas.13261
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08655, KAKENHI-PROJECT-17K09027, KAKENHI-PLANNED-17H06329
[Journal Article] Development of a fully automated chemiluminescence immunoassay for urine monomeric laminin-γ2 as a promising diagnostic tool of non-muscle invasive bladder cancer2017
- Author(s)
  Nakagawa Masatoshi、Karashima Takashi、Kamada Masayuki、Yoshida Eisaku、Yoshimura Toru、Nojima Masanori、Inoue Keiji、Shuin Taro、Seiki Motoharu、Koshikawa Naohiko
- Journal Title
  
  Biomark Res.
  
  Volume: 5 Issue: 1 Pages: 1-9
- DOI
  10.1186/s40364-017-0109-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09027, KAKENHI-PLANNED-17H06329
[Journal Article] Specific detection of soluble EphA2 fragments in blood as a new biomarker for pancreatic cancer2017
- Author(s)
  Koshikawa Naohiko、Minegishi Tomoko、Kiyokawa Hirofumi、Seiki Motoharu
- Journal Title
  
  Cell Death Dis
  
  Volume: 8 Issue: 10 Pages: e3134-e3134
- DOI
  10.1038/cddis.2017.545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09027, KAKENHI-PROJECT-16H04695, KAKENHI-PLANNED-17H06329
[Journal Article] A novel biomarker for diagnosis of bladder cancer2015
- Author(s)
  Koshikawa, N
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 146 Issue: 5 Pages: 248-251
- DOI
  10.1254/fpj.146.248
- NAID
  130005108617
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462471
[Journal Article] Urinary laminin-γ2 is a novel biomarker of non-muscle invasive urothelial　carcinoma2015
- Author(s)
  Kamada M, Koshikawa N, Minegishi T, Kawada C, Karashima T, Shuin T, & Seiki M
- Journal Title
  
  Cancer Sci
  
  Volume: 106(12) Pages: 1730-7
- Data Source
  KAKENHI-PROJECT-15KT0016
[Journal Article] Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein2015
- Author(s)
  Koshikawa N, Hoshino D, Taniguchi H, Minegishi T, Tomari T, Nam SO, Aoki M, Sueta T, Nakagawa T, Miyamoto S, Nabeshima K, Weaver AM, Seiki M
- Journal Title
  
  Cancer Res
  
  Volume: 75(16) Pages: 3327-39
- Data Source
  KAKENHI-PROJECT-15KT0016
[Journal Article] Association of SIRT1 and tumor suppressor gene TAp63 expression in head and neck squamous cell carcinoma2015
- Author(s)
  Kikuchi K, Noguchi A, Kasajima R, Miyagi Y, Hoshino D, Koshikawa N, Kubota A, Yokose T, Takano Y
- Journal Title
  
  Tumour Biol
  
  Volume: 36(10) Pages: 7865-72
- Data Source
  KAKENHI-PROJECT-15KT0016
[Journal Article] Tropomodulin 1 expression driven by NF-kB enhances breast cancer growth.2015
- Author(s)
  Ito-Kureha, T., Koshikawa, N., Yamamoto, M., Semba, K., Yamaguchi, N., Yamamoto, T., Seiki, M. and Inoue, J.
- Journal Title
  
  Cancer Res
  
  Volume: 75 Issue: 1 Pages: 62-72
- DOI
  10.1158/0008-5472.can-13-3455
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22117001, KAKENHI-PUBLICLY-25121734, KAKENHI-PROJECT-25460356, KAKENHI-PROJECT-26290036, KAKENHI-PROJECT-25462471
[Journal Article] Urinary laminin-γ2 is a novel biomarker of non-muscle invasive urothelial　carcinoma.2015
- Author(s)
  Kamada M, Koshikawa N, Minegishi T, Kawada C, Karashima T, Shuin T, & Seiki M.
- Journal Title
  
  Cancer Science
  
  Volume: 106 Issue: 12 Pages: 1730-7
- DOI
  10.1111/cas.12832
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462471
[Journal Article] Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein. Cancer Res2015
- Author(s)
  Koshikawa N, Hoshino D, Taniguchi H, Minegishi T, Tomari T, Nam SO, Aoki M, Sueta T, Nakagawa T, Miyamoto S, Nabeshima K, Weaver AM, Seiki M
- Journal Title
  
  Cancer Res
  
  Volume: 75(16) Issue: 16 Pages: 3327-39
- DOI
  10.1158/0008-5472.can-14-2798
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0016, KAKENHI-PROJECT-25462471
[Journal Article] Critical role of transient activity of MT1-MMP for ECM degradation in invadopodia.2013
- Author(s)
  Watanabe A, Hoshino D, Koshikawa N, Seiki M, Suzuki T, Ichikawa K.
- Journal Title
  
  PLoS Comput Biol.
  
  Volume: 9(5) Issue: 5 Pages: e1003086-e1003086
- DOI
  10.1371/journal.pcbi.1003086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05013, KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-25462471
[Journal Article] The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia2013
- Author(s)
  Hoshino, D., Nagano, M., Saitoh, A., Koshikawa, N., Suzuki, T., and Seiki, M
- Journal Title
  
  PLos One
  
  Volume: 8(1)
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Critical role of transient activity of MT1-MMP for ECM degradation in invadopodia2013
- Author(s)
  Watanabe, A., Hoshino, D., Koshikawa, N., Seiki, M., Suzuki, T., and Ichikawa, K
- Journal Title
  
  PLos Comput Biol
  
  Volume: 9(5)
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Control and inhibition analysis of complex formation processes2012
- Author(s)
  Saitou, T., Itano, K., Hoshino, D., Koshikawa, N., Seiki, M., Ichikawa, K., and Suzuki, T
- Journal Title
  
  Theor Biol Med Model
  
  Volume: 9 Pages: 33-33
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Detection of the heterogeneous O-glycosylation profile of MT1-MMPexpressed in cancer cells by a simple MALDI-MS method.2012
- Author(s)
  Shuo T, Koshikawa N, Hoshino D, Minegishi T, Ao-Kondo H, Oyama M, Sekiya S, Iwamoto S, Tanaka K, Seiki M.
- Journal Title
  
  PLoS One.
  
  Volume: 7(8) Issue: 8 Pages: e43751-e43751
- DOI
  10.1371/journal.pone.0043751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591762, KAKENHI-PROJECT-22700375, KAKENHI-PUBLICLY-23117507, KAKENHI-PROJECT-23510254
[Journal Article] Identification of proteins that associate with integrin alpha2 by proteomic analysis in human fibrosarcoma HT-1080 cells2012
- Author(s)
  Uematsu, T., C. Konishi, D. Hoshino, X. Han, Taizotomari, N. Egawa, Y. Takada, T. Isobe, M. Seiki, and N. Koshikawa
- Journal Title
  
  J Cell Physiol
  
  Volume: 8 Pages: 3072-9
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Identification of proteins that associate with integrin α2 by proteomic analysis in human fibrosarcoma HT-1080 cells.2012
- Author(s)
  Uematsu T, Konishi C, Hoshino D, HanX, Tomari T, Egawa N, Takada Y, IsobeT, Seiki M, Koshikawa N.
- Journal Title
  
  J Cell Physiol.
  
  Volume: 227(8) Issue: 8 Pages: 3072-9
- DOI
  10.1002/jcp.23054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23117507, KAKENHI-PROJECT-23790919
[Journal Article] The phosphoinositide-binding protein ZF21 regulates ECM degradation by invadopodia.2012
- Author(s)
  Hoshino D, Nagano M, Saitoh A, Koshikawa N, Suzuki T, Seiki M.
- Journal Title
  
  PLoS One.
  
  Volume: 8(1) Issue: 1 Pages: 1-8
- DOI
  10.1371/journal.pone.0050825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PUBLICLY-23117507, KAKENHI-PROJECT-23790109, KAKENHI-PROJECT-25462471
[Journal Article] Mathematical modeling of invadopodia formation2012
- Author(s)
  T.Saitou, M.Rouzimaimaiti, N.Koshikawa, M.Seiki, K.Ichikawa, T.Suzuki
- Journal Title
  
  J.Theoretical Biology
  
  Volume: 298 Pages: 138-146
- DOI
  10.1016/j.jtbi.2011.12.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20340034, KAKENHI-PLANNED-22117008, KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23117507
[Journal Article] Control and inhibition analysis of complex formation processes.2012
- Author(s)
  Saitou T, Itano K, Hoshino D, Koshikawa N, Seiki M, Ichikawa K, Suzuki T.
- Journal Title
  
  Theor Biol Med Model.
  
  Volume: 3 Issue: 1 Pages: 33-33
- DOI
  10.1186/1742-4682-9-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23117507, KAKENHI-PLANNED-22117008
[Journal Article] Detection of the heterogeneous O-glycosylation profile of MT1-MMP expressed in cancer cells by a simple MALDI-MS method2012
- Author(s)
  Shuo, T., Koshikawa, N., Hoshino, D., Minegishi, T., Ao-Kondo, H., Oyama, M., Sekiya, S., Iwamoto, S., Tanaka, K., and Seiki, M
- Journal Title
  
  PLos One
  
  Volume: 7(8)
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] MT1-MMP plays a critical role in henatopoiesis by regulating HIF-mediated chemo-/cytokine gene transcription within niche cells.2012
- Author(s)
  Chiemi Nishida, Kaori Kusubata, Yoshihiko Tashiro, Ismael Gritli, Aki Sato, Makiko Ohki-Koizumi, Yohei Morita, Makoto Nagano, Takeharu Sakamoto, Naohiko Koshikawa, Takahiro Kuchimaru, Shinae Kizaka-Kondoh, Motoharu Seiki, Hiromitsu Nakauchi, Beate Heissig, and Koichi Hattori.
- Journal Title
  
  Blood
  
  Volume: 119 Issue: 23 Pages: 5404-5416
- DOI
  10.1182/blood-2011-11-390849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J00480, KAKENHI-PROJECT-12J04973, KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23013009, KAKENHI-PROJECT-23591371, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24591313, KAKENHI-PROJECT-24591382, KAKENHI-PLANNED-22112007, KAKENHI-PLANNED-22112009, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23112505
[Journal Article] Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies2012
- Author(s)
  Hoshino, D., N. Koshikawa, T . Suzuki, V . Quaranta, A. Weaver, M. Seiki and K. Ichikawa
- Journal Title
  
  PLos Computational Biology
  
  Volume: 8(4)
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Establishment and validation of computational model for MT1-MMP dependent ECM degradation and intervention strategies2012
- Author(s)
  Hoshino, D., Koshikawa, N., Suzuki, T., Quaranta, V., Weaver, A.M., (Seiki, M.), Ichikawa, K.
- Journal Title
  
  PLoS Comp.Biol.
  
  Volume: 8 Issue: 4 Pages: e1002479-e1002479
- DOI
  10.1371/journal.pcbi.1002479
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22117008, KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23117507
[Journal Article] Turnover of focal adhesions and cancer cell migration.2012
- Author(s)
  Nagano M, Hoshino D, Koshikawa N, Akizawa T, Seiki M.
- Journal Title
  
  Int J Cell Biol.
  
  Volume: 2012 Pages: 310616-310616
- DOI
  10.1155/2012/310616
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23117507, KAKENHI-PROJECT-23790109
[Journal Article] MT1-MMP plays a critical role in hematopoiesis by regulating HIF-mediated chemokine/cytokine gene transcription within niche cells2012
- Author(s)
  Nishida, C., Kusubata, K., Tashiro, Y., Gritli, I., Sato, A., Ohki-Koizumi, M., Morita, Y., Nagano, M., Sakamoto, T., Koshikawa, N., Kuchimaru, T., Kizaka-Kondoh, S., Seiki, M., Nakauchi, H., Heissig, B., and Hattori, K
- Journal Title
  
  Blood
  
  Volume: 119(23) Pages: 5405-16
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Turnover of focal adhesions and cancer cell migration2012
- Author(s)
  Nagano, M., D. Hoshino, N. Koshikawa, T. Akizawa, and M. Seiki
- Journal Title
  
  Int J Cell Biol
  
  Volume: 2012 Pages: 310616-310616
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinase-1 in ovarian carcinoma cells2011
- Author(s)
  越川直彦、清木元治, 9/9番目
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 111-6
- NAID
  10029288679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Cholestatic liver fibrosis and toxin-induced fibrosis are exacerbated in matrix metalloproteinase-2 deficient mice2011
- Author(s)
  Onozuka I, Sakamoto N, Nakagawa M, Watanabe M, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Issue: 1 Pages: 134-140
- DOI
  10.1016/j.bbrc.2011.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390226, KAKENHI-PROJECT-21590831, KAKENHI-PROJECT-21590832, KAKENHI-PROJECT-22591762, KAKENHI-PROJECT-22659145, KAKENHI-PUBLICLY-23117507, KAKENHI-PROJECT-23689040
[Journal Article] ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain2011
- Author(s)
  Nagano M, Hoshino D, Koshiba S, Shuo T Koshikawa N, Tomizawa T, Hayashi F, Tochio N, Harada T, Akizawa T Watanabe S, Handa N, Shirouzu M, Kigawa T, Yokoyama S, Seiki M
- Journal Title
  
  J Biol Chem.
  
  Volume: 286(36) Issue: 36 Pages: 31598-609
- DOI
  10.1074/jbc.m110.199430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22591762, KAKENHI-PROJECT-22700375, KAKENHI-PUBLICLY-23117507, KAKENHI-PROJECT-23790109
[Journal Article] Expression of laminin 5-Y2 chain in cutaneous squamous cell carcinoma and its role in tumour invasion.2011
- Author(s)
  Hamasaki H, Koga K, Aoki M, Hamasaki M, Koshikawa N, Seiki M, Iwasaki H, Nakayama J, Nabeshima K
- Journal Title
  
  Br J Cancer.
  
  Volume: 6;105(6) Issue: 6 Pages: 824-32
- DOI
  10.1038/bjc.2011.283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23117507, KAKENHI-PROJECT-23590419
[Journal Article] Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinase-1 in ovarian carcinoma cells2011
- Author(s)
  Koshikawa, N., H. Mizushima, T. Minegishi, F. Eguchi, F. Yotsumoto, K. Nabeshima, S. Miyamoto, E. Mekada, and M. Seiki
- Journal Title
  
  Cancer Sci
  
  Volume: 102(1) Pages: 111-6
- NAID
  10029288679
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Membrane-type 4 matrix metalloproteinase (MT4-MMP)modulates water homeostasis in mice.2011
- Author(s)
  Srichai MB, Colleta H, Gewin L, Matrisian L, Abel TW, Koshikawa N, Seiki M, Pozzi A, Harris RC, Zent R.
- Journal Title
  
  PLoS One.
  
  Volume: 6(2) Issue: 2 Pages: e17099-e17099
- DOI
  10.1371/journal.pone.0017099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591762, KAKENHI-PUBLICLY-23117507
[Journal Article] ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center.2011
- Author(s)
  14: Nagano M, Hoshino D, Sakamoto T, Akizawa T, Koshikawa N, Seiki M.
- Journal Title
  
  Cell Adh Migr.
  
  Volume: 5(1) Pages: 23-8
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinase-1 in ovarian carcinoma cells.2011
- Author(s)
  13: Koshikawa N, Mizushima H, Minegishi T, Eguchi F, Yotsumoto F, Nabeshima K, Miyamoto S, Mekada E, Seiki M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 102(1) Issue: 1 Pages: 111-6
- DOI
  10.1111/j.1349-7006.2010.01748.x
- NAID
  10029288679
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC2011
- Author(s)
  Hoshino, D., N. Koshikawa, and M. Seiki
- Journal Title
  
  J Biol Chem
  
  Volume: 286(4) Pages: 3139-48
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Proteolytic activation of heparin-binding EGF-like growth factor by membrane-type matrix metalloproteinasel in ovarian carcinoma cells.2011
- Author(s)
  Koshikawa, N., et al.
- Journal Title
  
  Cancer Science
  
  Volume: 102 Pages: 111-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] ZF21 is a new regulator of focal adhesion disassembly and a potential member of the spreading initiation center2011
- Author(s)
  Nagano, M., D. Hoshino, T. Sakamoto, T. Akizawa, N. Koshikawa, and M. Seiki
- Journal Title
  
  Cell Adh Migr
  
  Volume: 5(1) Pages: 23-8
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] A p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.2011
- Author(s)
  12: Hoshino D, Koshikawa N, Seiki M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 286(4) Issue: 4 Pages: 3139-48
- DOI
  10.1074/jbc.m110.159715
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] A p27 (kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.2011
- Author(s)
  Hoshino, D, Koshikawa, N., et al
- Journal Title
  
  J Biol.Chem.
  
  Volume: 286 Pages: 3139-3148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] MT1-MMP-mediated basement membrane remodeling modulates renal development.2010
- Author(s)
  15: Riggins KS, Mernaugh G, Su Y, Quaranta V, Koshikawa N, Seiki M, Pozzi A, Zent R.
- Journal Title
  
  Exp Cell Res.
  
  Volume: 316(17) Issue: 17 Pages: 2993-3005
- DOI
  10.1016/j.yexcr.2010.08.003
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] ZF21 protein regulates cell adhesion and motility2010
- Author(s)
  Nagano, M., D. Hoshino, T. Sakamoto, N. Kawasaki, N. Koshikawa, and M. Seiki
- Journal Title
  
  J Biol Chem
  
  Volume: 285(27) Pages: 21013-22
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor2010
- Author(s)
  Koshikawa, N., H. Mizushima, T. Minegishi, R. Iwamoto, E. Mekada, and M. Seiki
- Journal Title
  
  Cancer Res
  
  Volume: 70(14) Pages: 6093-103
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor2010
- Author(s)
  越川直彦、清木元治, 6/6番目
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 6093-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into aheparin-independent growth factor.2010
- Author(s)
  Koshikawa N, Mizushima H, Minegishi T, Iwamoto R, Mekada E, Seiki M.
- Journal Title
  
  Cancer Res.
  
  Volume: 70(14) Issue: 14 Pages: 6093-103
- DOI
  10.1158/0008-5472.can-10-0346
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] ZF21 protein regulates cell adhesion and motility.2010
- Author(s)
  Nagano M, Hoshino D, Sakamoto T, Kawasaki N, Koshikawa N, Seiki M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 285(27) Issue: 27 Pages: 21013-22
- DOI
  10.1074/jbc.m110.106443
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] ZF21 protein, a regulator of the disassembly of focal adhesions and cancer metastasis, contains a novel noncanonical pleckstrin homology domain2010
- Author(s)
  Nagano, M., D. Hoshino, S. Koshiba, T. Shuo, N. Koshikawa, T. Tomizawa, F. Hayashi, N. Tochio, T. Harada, T. Akizawa, S. Watanabe, N. Handa, M. Shirouzu, T. Kigawa, S. Yokoyama, and M. Seiki
- Journal Title
  
  J Biol Chem
  
  Volume: 286(36) Pages: 31598-609
- Data Source
  KAKENHI-PROJECT-22220014
[Journal Article] Membrane type 1-matrix metalloproteinase cleaves off the NH2-terminal portion of heparin-binding epidermal growth factor and converts it into a heparin-independent growth factor.2010
- Author(s)
  Koshikawa, N, et al
- Journal Title
  
  Cancer Res.
  
  Volume: 70 Pages: 6093-6103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591762
[Journal Article] Identification and characterization of Lutheran blood group glycoprotein as a new substrate of membrane-type 1 matrix metalloproteinase 1 (MT1-MMP) : asystemic whole cell analysis of MT1-MMP-associating proteins in A431 cells.2009
- Author(s)
  Niiya, D., N.Egawa, T.Sakamoto, Y.Kikkawa, T.Shinkawa, T.Isobe, N.Koshikawa, M.Seiki.
- Journal Title
  
  J Biol Chem 284
  
  Pages: 27360-27369
- Data Source
  KAKENHI-PROJECT-17014019
[Journal Article] High throughput analysis of proteins associating with a proinvasive MT1-MMP in human malignant melanoma A375 cells.2009
- Author(s)
  Tomari, T., N.Koshikawa, T.Uematsu, T.Shinkawa, D.Hoshino, N.Egawa, T.Isobe, M.Seiki.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 1284-1290
- NAID
  10027192295
- Data Source
  KAKENHI-PROJECT-17014019
[Journal Article] A novel protein associated with membrane-type 1 matrix metalloproteinase binds p27 (kip1) and regulates RhoA activation, actinremodeling, and matrigel invasion.2009
- Author(s)
  Hoshino, D., T.Tomari, M.Nagano, N.Koshikawa, M.Seiki.
- Journal Title
  
  J BiolChem 284
  
  Pages: 27315-27326
- Data Source
  KAKENHI-PROJECT-17014019
[Journal Article] Development of a new tracking tool for the human monomeric laminin-gamma 2 chain in vitro and in vivo2008
- Author(s)
  Koshikawa, N., Seiki, M., (他2名)
- Journal Title
  
  Cancer Research 68
  
  Pages: 530-536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014019
[Journal Article] Development of a new tracking tool for the human monomeric laminin-gamma 2 chain in vitro and in vivo.2008
- Author(s)
  Koshikawa, N., T.Minegishi, K.Nabeshima, M.Seiki.
- Journal Title
  
  Cancer Res 68
  
  Pages: 530-536
- Data Source
  KAKENHI-PROJECT-17014019
[Journal Article] Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells.2006
- Author(s)
  Egawa, N., N.Koshikawa, T.Tomari, K.Nabeshima, T.Isobe, M.Seiki.
- Journal Title
  
  J Biol Chem 281
  
  Pages: 37576-37585
- Data Source
  KAKENHI-PROJECT-17014019
[Journal Article] Membrane-type-1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-KDA EMMPRIN fragment from tumor cells2006
- Author(s)
  Egawa, N, Koshikawa, N. et al.
- Journal Title
  
  J. Biol. Chem. 284, 49
  
  Pages: 37576-37585
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590336
[Journal Article] Membrane-type-1 matrix metalloproteinase(MT1-MMP/MMP-14) cleaves and releases a 22-KDA EMMPRIN fragment from tumor cells2006
- Author(s)
  Egawa, N, Koshikawa, N.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 37576-37585
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590336
[Journal Article] Membrane-type-1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-KDA EMMPRIN fragment from tumor cells2006
- Author(s)
  Egawa, N, Koshikawa, N. et al.
- Journal Title
  
  J. Biol. Chem. 284,49
  
  Pages: 37576-37585
- Data Source
  KAKENHI-PROJECT-17590336
[Journal Article] Membrane-type matrix metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gamma 2 chain.2005
- Author(s)
  Koshikawa, N., T.Minegishi, A.Sharabi, V.Quaranta, M.Seiki.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 88-93
- Data Source
  KAKENHI-PROJECT-17014019
[Journal Article] Membrane-type metalloproteinase-1 (MT1-MMP) is a processing enzyme for human laminin gammma2 chain2005
- Author(s)
  Koshikawa, N. et al.
- Journal Title
  
  Journal Biological Chemistry 280
  
  Pages: 88-93
- Data Source
  KAKENHI-PROJECT-15790146
[Journal Article] Membrane-type Matrix Metalloproteinase-1 (MT1-MMP) is a Processing Enzyme for Human Laminin gamma2 chain2005
- Author(s)
  Koshikawa, N. et al.
- Journal Title
  
  The Journal of Biological Chemistry 280
  
  Pages: 88-93
- Data Source
  KAKENHI-PROJECT-17590336
[Journal Article] Proteolytic processing of laminin-5 by MT1-MMP in tissues and its effects on epithelial cell morphology2004
- Author(s)
  Koshikawa, N. et al.
- Journal Title
  
  FASEB Journal 18
  
  Pages: 364-366
- Data Source
  KAKENHI-PROJECT-15790146
[Patent] 細胆管増生を伴う肝細胞を検出するためのバイオマーカー2021
- Inventor(s)
  山下太郎、岡田光、金子周一、舟橋伸昭、清木元治、越川直彦
- Industrial Property Rights Holder
  山下太郎、岡田光、金子周一、舟橋伸昭、清木元治、越川直彦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-121616
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-21K09840
[Patent] LAMC2-NR6A1スプライシングバリアント及びその翻訳産物2019
- Inventor(s)
  星野大輔、清木元治、越川直彦
- Industrial Property Rights Holder
  東京大学、神奈川県立病院機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-029791
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-17K09027
[Patent] EphA2 N末端フラグメント抗体2018
- Inventor(s)
  越川直彦、清木元治
- Industrial Property Rights Holder
  国立大学法人東京大学、神奈川県立病院機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-534429
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H04695
[Patent] EphA2 N末端フラグメント抗体2018
- Inventor(s)
  越川直彦、清木元治
- Industrial Property Rights Holder
  東京大学、神奈川県立病院機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-534429
- Filing Date
  2018
- Data Source
  KAKENHI-PLANNED-17H06329
[Patent] EphA2 N末端フラグメント抗体2017
- Inventor(s)
  越川直彦、清木元治
- Industrial Property Rights Holder
  東京大学、神奈川県立病院機構
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-17K09027
[Patent] METHODS OF DIAGNOSING HEPATOCELLULAR CARCINOMA AND PANCREATIC CANCER2015
- Inventor(s)
  越川直彦、清木元治、吉田栄作、吉村徹
- Industrial Property Rights Holder
  東京大学、アボットラボラトリーズ
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-28
- Overseas
- Data Source
  KAKENHI-PROJECT-25462471
[Patent] がんの検査方法及び検査用キット2014
- Inventor(s)
  清木元治、越川直彦
- Industrial Property Rights Holder
  清木元治、越川直彦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-026026
- Filing Date
  2014-02-13
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] がんの検査方法及び検査用キット2014
- Inventor(s)
  清木元治, 越川直彦
- Industrial Property Rights Holder
  清木元治, 越川直彦
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-13
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] がんの検査方法及び検査用キット2014
- Inventor(s)
  越川直彦、清木元治
- Industrial Property Rights Holder
  越川直彦、清木元治
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-026026
- Filing Date
  2014-02-13
- Overseas
- Data Source
  KAKENHI-PUBLICLY-23117507
[Patent] がんの検査方法及び検査用キット2014
- Inventor(s)
  清木元治, 越川直彦
- Industrial Property Rights Holder
  清木元治, 越川直彦
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-13
- Overseas
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] がんの検査方法及び検査用キット2014
- Inventor(s)
  清木元治、越川直彦
- Industrial Property Rights Holder
  清木元治、越川直彦
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-13
- Overseas
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] 同一試料中の2種の物質を検出又は測定する方法2013
- Inventor(s)
  清木元治, 越川直彦
- Industrial Property Rights Holder
  清木元治, 越川直彦
- Industrial Property Rights Type
  特許
- Filing Date
  2013-07-05
- Overseas
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] METHODS OF PROGNOSIS AND DIAGNOSIS FOR CANCER2012
- Inventor(s)
  清木元治,越川直彦,中川将利,吉田栄作,吉村徹
- Industrial Property Rights Holder
  清木元治,越川直彦,中川将利,吉田栄作,吉村徹
- Industrial Property Rights Type
  特許
- Filing Date
  2012-08-13
- Overseas
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] METHODS OF PROGNOSIS AND DIAGNOSIS FOR CANCER2012
- Inventor(s)
  清木元治, 越川直彦, 中川将利, 吉田栄作, 吉村徹
- Industrial Property Rights Holder
  清木元治, 越川直彦, 中川将利, 吉田栄作, 吉村徹
- Industrial Property Rights Type
  特許
- Filing Date
  2012-08-13
- Overseas
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] 同一試料中の２種の物質を検出又は測定する方法2012
- Inventor(s)
  清木元治、越川直彦
- Industrial Property Rights Holder
  清木元治、越川直彦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-151610
- Filing Date
  2012-07-05
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] 泌尿器科がんの検査方法および検査用キット2011
- Inventor(s)
  清木元治, 越川直彦, 執印太朗, 鎌田雅行
- Industrial Property Rights Holder
  清木元治, 越川直彦, 執印太朗, 鎌田雅行
- Industrial Property Rights Type
  特許
- Filing Date
  2011-03-08
- Data Source
  KAKENHI-PROJECT-22220014
[Patent] 泌尿器科がんの検査方法及び検査用キット2010
- Inventor(s)
  清木元治、越川直彦、執印太郎、鎌田雅之
- Industrial Property Rights Holder
  東京大学、高知大学
- Filing Date
  2010-03-09
- Data Source
  KAKENHI-PROJECT-17014019
[Presentation] 肝がんにおいて、ラミニンγ２単鎖はEGFR活性化を介してがん悪性化進展を促進する2023
- Author(s)
  舟橋伸昭、越川直彦
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] 肝細胞癌における新規診断バイオマーカーのエピジェネティクスな発現・制御の研究2023
- Author(s)
  石川大空、越川直彦、舟橋伸昭
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] Chromosomal translocation converts a laminin gene, LAMC2, into an oncogene in ovarian carcinoma2023
- Author(s)
  Koshikawa N, Kaneko R, Funahashi N.
- Organizer
  Tissue, Matrix, and Pathobiology: Joint Meeting of ASMB
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] Lm-γ2 単鎖により誘導される EGFR/AKT 経路を介した肝細胞かがんの発症と悪性化に関する研究2023
- Author(s)
  舟橋伸昭、岡田光、山下太郎、越川直彦
- Organizer
  第82回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] 新規ラミニン融合遺伝子を発現するがん細胞の同定2023
- Author(s)
  兼子崚、舟橋伸昭、宮城洋平、越川直彦
- Organizer
  第82回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] 新規ラミニンγ2融合遺伝子による悪性化進展の分子機序の解明2022
- Author(s)
  越川直彦、宮城洋平
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] Identification of LAMC2-fusion gene as an oncoprotein produced by chromosomal translocation2022
- Author(s)
  Naohiko Koshikawa, Daisuke Hoshino, Yohei Miyagi
- Organizer
  第81回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] 新規ラミニンγ2融合遺伝子による悪性化進展の分子機序の解明2022
- Author(s)
  越川直彦、宮城洋平
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] ラミニンγ2単鎖により誘導される肝発がんの新規分子メカニズム2022
- Author(s)
  舟橋伸昭、岡田光、山下太郎、清木元治、金子周一、越川直彦
- Organizer
  第81回日本癌学会総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] ラミニンγ2単鎖をバイオマーカーとした肝発がん、遠隔転移の予測を可能とする新たな診断法の構築2022
- Author(s)
  越川直彦
- Organizer
  第72回日本電気泳動学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] Identification of LAMC2-fusion gene as an oncoprotein produced by chromosomal translocation2022
- Author(s)
  Naohiko Koshikawa, Daisuke Hoshino, Yohei Miyagi
- Organizer
  第81回日本癌学会総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] EphA2-EGFRシグナルのAKTへの収斂により制御される肝細胞がんの転移能2022
- Author(s)
  中村直俊、朝倉暢彦、池田一貴、野島陽水、鈴木貴、越川直彦
- Organizer
  第81回日本癌学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] ラミニンγ2単鎖をバイオマーカーとした肝発がん、遠隔転移の予測を可能とする新たな診断法の構築2022
- Author(s)
  越川直彦
- Organizer
  第72回日本電気泳動学会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 肝発がんにおける胆管上皮細胞由来ラミニンγ2単鎖が肝細胞の機能に及ぼす影響2022
- Author(s)
  舟橋伸昭、越川直彦
- Organizer
  第31回日本がん転移学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 肝発がんにおけるLn-γ2mの機能解析2021
- Author(s)
  舟橋伸昭、岡田光、山下太郎、金子周一、清木元治、越川直彦
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] がん幹細胞マーカーによる肝細胞がんの分類とEphA2シグナル伝達2021
- Author(s)
  朝倉暢彦、室井敦、中村直俊、野島陽水、越川直彦、鈴木貴
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] EphA2およびEGFRを介した肝細胞がん進展の数理モデリング2021
- Author(s)
  中村直俊、室井敦、朝倉暢彦、野島陽水、榎本将士、鈴木貴、越川直彦
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 新たな肝細胞がんを予測する新たなバイオマーカーとしての血清ラミニンγ2モノマー2021
- Author(s)
  越川直彦、山下太郎、中川将利、吉田栄作、吉村徹、金子周一、清木元治
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] ラミニンγ2単鎖が肝発がんに及ぼす新たな機能の解析2021
- Author(s)
  舟橋伸昭、越川直彦
- Organizer
  第30回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] ラミニンγ2単鎖が肝発がんに及ぼす新たな機能の解析2021
- Author(s)
  舟橋伸昭、越川直彦
- Organizer
  第30回日本がん転移学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 新たな肝細胞がんを予測する新たなバイオマーカーとしての血清ラミニンγ2モノマー2021
- Author(s)
  越川直彦、山下太郎、中川将利、吉田栄作、吉村徹、金子周一、清木元治
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] がん幹細胞マーカーによる肝細胞がんの分類とEphA2シグナル伝達2021
- Author(s)
  朝倉暢彦、室井敦、中村直俊、野島陽水、越川直彦、鈴木貴
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] EphA2およびEGFRを介した肝細胞がん進展の数理モデリング2021
- Author(s)
  中村直俊、室井敦、朝倉暢彦、野島陽水、榎本将士、鈴木貴、越川直彦
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K09840
[Presentation] 肝発がんにおけるLn-γ2mの機能解析2021
- Author(s)
  舟橋伸昭、岡田光、山下太郎、金子周一、清木元治、越川直彦
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 細胞表層でのプロテオリシスよるがん悪性化進展制御の解明とその産物の臨床応用2020
- Author(s)
  越川直彦
- Organizer
  横浜市大院・医学研究科大学院セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] Biostatistical analysis for malignant signaling pathways of hepatocellular carcinoma.2020
- Author(s)
  Koshikawa, N, Muroi A, Asakura N, Enomoto M, Ishiwata M, Suzuki T
- Organizer
  5th Core to Core Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] Mathematical modeling for EphA2 and EGF-receptor and their downstream signal pathways involved in malignant progression of hepatocellular carcinoma2019
- Author(s)
  Koshikawa, N.
- Organizer
  4th Core to Core Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] びまん性大細胞B細胞性リンパ腫における新規診断補助ツールとしての逆相蛋白質アレイの有用性について2019
- Author(s)
  鈴木理樹、室井敦、野島寛、酒井リカ、横瀬智之、宮城洋平、越川直彦
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] Mathematical modeling for EphA2 and EGF-receptor and their downstream signal pathways involved in malignant progression of hepatocellular carcinoma2019
- Author(s)
  Koshikawa, N
- Organizer
  4th Core to Core Meeting at Inria, Bordeaux, France
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 細胞表層でのプロテオリシスよるがん悪性化進展制御の解明とその産物の臨床応用2019
- Author(s)
  越川直彦
- Organizer
  宮崎大学大学院特別セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 数理モデルを用いたがんの悪性化進展制御の解明、第92回日本生化学会大会2019
- Author(s)
  室井敦、榎本将士、森達樹、石渡道徳、星野大輔、鈴木貴、越川直彦
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] Monomeric laminin-γ2 is a promising biomarker for cancer diagnosis2019
- Author(s)
  Koshikawa, N.
- Organizer
  Special Lecture at National Institute of Gastroenterology, S. De Bellis” Research Hospital at Bari
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] 相蛋白質アレイおよび数理モデルを用いた肝細胞がん悪性化制御シグナルの解析2019
- Author(s)
  室井敦、榎本将士、朝倉暢彦、森達樹、星野大輔、石渡道徳、鈴木貴、越川直彦
- Organizer
  第19回日本蛋白質化学学会年会、第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] 数理モデルを用いたがんの悪性化進展制御の解明2019
- Author(s)
  室井敦、榎本将士、森達樹、石渡道徳、星野大輔、鈴木貴、越川直彦
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] 数理モデルと逆相蛋白質アレイデータによる肝細胞がん悪性化シグナル経路の解析2019
- Author(s)
  鈴木貴、榎本将士、朝倉暢彦、室井敦、越川直彦
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] 逆相蛋白質アレイおよび数理モデルを用いた肝細胞がん悪性化制御シグナルの解析2019
- Author(s)
  室井敦、榎本将士、朝倉暢彦、森達樹、星野大輔、石渡道徳、鈴木貴、越川直彦
- Organizer
  第19回日本蛋白質化学学会年会、第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] Membrane type-1 matrix metalloproteinase (MT1-MMP) によるがん悪性化進展制御の解明とがん臨床への応用2019
- Author(s)
  越川直彦
- Organizer
  第854回千葉県がんセンター研究所集演会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 数理モデルと逆相蛋白質アレイデータによる肝細胞がん悪性化シグナル経路の解析2019
- Author(s)
  鈴木貴、榎本将士、朝倉暢彦、室井敦、越川直彦
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] Epha2 cleavage by MT1-MMP acts as a switch converting a tumor suppressor into an oncoprotein and could be a possible target for cancer diagnosis2018
- Author(s)
  Koshikawa N & Seiki M
- Organizer
  ISOBM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] 悪性がんのバイオマーカーとしてのラミニンγ2単鎖2018
- Author(s)
  越川直彦
- Organizer
  第27回日本がん転移学会学術集会（横浜）会長講演
- Invited
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] MT1-MMPによるEphA2の限定分解（プロセシング）を介したがん悪性化進展制御の分子機序の解明2018
- Author(s)
  越川直彦
- Organizer
  第50回日本結合組織学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] 悪性がんのバイオマーカーとしてのラミニンγ2単鎖2018
- Author(s)
  越川直彦
- Organizer
  第27回日本がん転移学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 膜型MMP1(MT1-MMP)とその周辺分子を標的としたがん治療・診断の新戦略2018
- Author(s)
  越川直彦
- Organizer
  藤田保健衛生大学医学セミナー
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] MT1-MMPによるEphA2の限定分解（プロセシング）を介したがん悪性化進展制御の分子機序の解明2018
- Author(s)
  越川直彦
- Organizer
  第50回日本結合組織学会学術大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] がん抑制因子から促進因子に変換するEphA2プロセシングの解明2018
- Author(s)
  1.越川直彦、星野大輔、清木元治
- Organizer
  第77回日本癌学会学術総会（大阪）
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] がん抑制因子から促進因子に変換するEphA2プロセシングの解明2018
- Author(s)
  越川直彦、星野大輔、清木元治
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] 肝がん診断の新規バイオマーカーの開発2017
- Author(s)
  中川将利、吉田栄作、吉村徹、清木元治、越川直彦
- Organizer
  第26回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] 新たな肝細胞がんの早期診断法の開発2017
- Author(s)
  越川直彦
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] EphA2プロテオリシスによるがん悪性化シグナル制御の解明2017
- Author(s)
  越川直彦、清木元治
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] 新たな肝細胞がんの早期診断法の開発2017
- Author(s)
  越川直彦
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] Analysis of MT1-MMP-mediated signaling network in vivo using reverse phase protein assay (RPPA) and mathematical modeling2017
- Author(s)
  Koshikawa N
- Organizer
  2nd Core to Core Meeting at Vanderbilt University
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] エクソソームは細胞膜突起構造を増強し、浸潤活性を惹起する2017
- Author(s)
  星野大輔、清木元治、越川直彦
- Organizer
  第76回日本癌学会学術総会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] EphA2 proteolysis converts it from tumor suppressor to oncoprotein2017
- Author(s)
  Koshikawa N
- Organizer
  Vanderbilt University Quantitative system biology center (QSBC) meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] エクソソームは細胞膜突起構造を増強し、浸潤活性を惹起する2017
- Author(s)
  星野大輔、清木元治、越川直彦
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09027
[Presentation] エクソソームは細胞膜突起構造を増強し、浸潤活性を惹起する2017
- Author(s)
  星野大輔、清木元治、越川直彦
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] EphA2プロテオリシスによるがん悪性化シグナル制御の解明2017
- Author(s)
  越川直彦、清木元治
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06329
[Presentation] 新たな肝細胞がん診断のバイオマーカーの同定2016
- Author(s)
  越川直彦、安田宏、清川寛、伊東文生、中川将利、吉田栄作, 吉村徹, 清木元治
- Organizer
  日本がん学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16H04695
[Presentation] Comprehensive analysis of the pro-oncogenic signaling induced by proteolysis of MT1-MMP substrate in vivo2016
- Author(s)
  Koshikawa, N
- Organizer
  The First JSPS Core-to-Core Seminar: Establishing International Research Network of Mathematical Oncology
- Place of Presentation
  大和高原ボスコヴィラ（奈良県・奈良市）
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-15KT0016
[Presentation] がん悪性化シグナルの伝達装置としてのMT1-MMP2015
- Author(s)
  越川直彦、星野大輔、清木元治
- Organizer
  第24回日本がん転移学会学術集会・総会
- Place of Presentation
  大阪
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-25462471
[Presentation] 新規膀胱がん診断法の開発2015
- Author(s)
  中川将利、越川直彦、鎌田雅行、吉田栄作、吉村徹、執印太郎、清木元治
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25462471
[Presentation] Membrane type-1 matrix metalloproteinase promotes invasive growth signals of cancer cells by cell surface proteolysis2013
- Author(s)
  Koshikawa, N., Seiki, M.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Membrane type-1 matrix metalloproteinase (MT1-MMP) is a potent regulator of cancer malignant progression through the heparin-binding EGF-like growth factor activation2013
- Author(s)
  Naohiko KOSHIKAWA
- Organizer
  AACR special conference "Invasion and Metastasis"
- Place of Presentation
  San Diego, CA USA
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] Membrane type- 1 matrix metalloproteinase promotes invasive growth signals of cancer cells by cell surface proteolysis2013
- Author(s)
  Koshikawa, N., Seiki, M
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Membrane type-1 matrix metalloproteinase is a potent regulator of cancer malignant progression through the heparin-binding EGF-like growth factor activation.2013
- Author(s)
  Koshikawa, N. et al.
- Place of Presentation
  San Diego, USA
- Year and Date
  2013-01-24
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] ヒト癌細胞においてインテグリンα2β1と複合体を形成する蛋白質のプロテオミクスによる同定と解析2012
- Author(s)
  小西知江子、星野大輔、越川直彦、清木元治
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] 卵巣がんにおけるMT1-MMPによるHB-EGFの活性化についての研究2012
- Author(s)
  越川直彦、清木元治
- Organizer
  第21回　日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] 尿中腫瘍分泌蛋白 X 検出による尿路上皮癌診断の可能性2012
- Author(s)
  鎌田雅行、越川直彦他
- Organizer
  日本癌治療学会
- Place of Presentation
  横浜
- Year and Date
  2012-10-25
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] Proteolytic activation of HB-EGF by MT1-MMP in ovarian carcinoma cells2011
- Author(s)
  越川直彦, 他
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PUBLICLY-23117507
[Presentation] がん細胞膜上の微小環境-悪性化制御因子としてのMT1-MMP-2011
- Author(s)
  越川直彦, 他
- Organizer
  第20回日本がん転移学会学術総会
- Place of Presentation
  浜松(招待講演)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] 悪性乳がんにおける、造腫瘍機能促進に関与する新規NF-κB標的遺伝子の解析2011
- Author(s)
  呉羽拓、山口憲孝、越川直彦、渡辺慎哉、清木元治、仙波健太郎、井上純一郎
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] がん細胞膜上の微小環境2011
- Author(s)
  越川直彦他
- Organizer
  第20回日本がん転移学会学術総会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] がん微小環境での悪性化制御因子としてのMT1-MMPの役割2011
- Author(s)
  越川直彦
- Organizer
  日本癌学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] MT1-MMP is a potent regulator of malignant progression in tumor microenvironment.2011
- Author(s)
  Koshikawa, N., Seiki. M.
- Organizer
  Mathematical Methods in Cancer Cell Biology
- Place of Presentation
  Hiroshima
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] Proteolytic activation of HB-EGF by MT1-MMP inovarian carcinoma cells.2011
- Author(s)
  Koshikawa, N. et al.
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] MT1-MMP is a potent regulator of malignant progression in tumor microenvironment2011
- Author(s)
  Koshikawa, N., Seiki, M
- Organizer
  Mathematical Methods in Cancer Cell Biology
- Place of Presentation
  Hiroshima, Japan(招待講演)
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] Proteolytic activation of HB-EGF by MT1-MMP in ovarian carcinoma cells2011
- Author(s)
  越川直彦, 他
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] がん細胞膜上の微小環境-悪性化制御因子としてのMT1-MMP-2011
- Author(s)
  越川直彦, 他
- Organizer
  第20回日本がん転移学会学術総会
- Place of Presentation
  浜松(招待講演)
- Year and Date
  2011-06-30
- Data Source
  KAKENHI-PUBLICLY-23117507
[Presentation] Proteolytic activation of HB-EGF by MT1-MMP in ovarian carcinoma cells2011
- Author(s)
  越川直彦、鍋島一樹、宮本新吾、目加田英輔、清木元治
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] がん細胞膜上の微小環境-悪性化制御因子としてのMT1-MMP-2011
- Author(s)
  越川直彦、清木元治
- Organizer
  第20回日本がん転移学会学術総会
- Place of Presentation
  浜松
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] MT1-MMP is a potent regulator of malignant progression in tumor micro environment2011
- Author(s)
  Koshikawa, N., Seiki, M.
- Organizer
  Mathematical Methods in Cancer Cell Biology
- Place of Presentation
  Hiroshima, Japan(招待講演)
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PUBLICLY-23117507
[Presentation] MT1-MMP is a potent regulator of malignant progression in tumor microenvironment.2011
- Author(s)
  Koshikawa, N. et al.
- Organizer
  国際研究集会「がん細胞の数理科学」
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] がん微小環境での悪性化制御因子としてのMT1-MMPの役割2010
- Author(s)
  越川直彦、清木元治
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪市)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] MT1-MMP is a potent regulator of malignant progression in tumor microenvironment2010
- Author(s)
  越川直彦
- Organizer
  米国マトリックス生物学会総会
- Place of Presentation
  米国・チャールストン
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] MT1-MMPによるLuのプロセシングを介した細胞接着制御についての検討2010
- Author(s)
  越川直彦、清木元治
- Organizer
  第19回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール(金沢市)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22220014
[Presentation] MT1-MMP is a potent regulator of malignant progression in tumor microenvironment.2010
- Author(s)
  Koshikawa, N. et al.
- Organizer
  米国マトリックス生物学会 10 周年記念総会
- Place of Presentation
  Charleston, USA
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] がん微小環境での悪性化制御因子としてのMT1-MMPの役割2010
- Author(s)
  越川直彦他
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22591762
[Presentation] 膜型MMPによる細胞表層のプロテオリシスと癌細胞の悪性形質の制御2007
- Author(s)
  越川直彦、清木元治
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-17014019
[Presentation] ラミニンγ2単鎖に特異的に反応するモノクリナール抗体の作製2007
- Author(s)
  越川直彦、清木元治
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜市
- Data Source
  KAKENHI-PROJECT-17014019
[Presentation] がんの生物像を規定する微小環境:膜型MMPによる細胞表層のプロテオリシスと癌細胞の悪性形質の獲得2006
- Author(s)
  越川直彦、清木元治
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014019
[Presentation] Membrane type-1 matrix metalloproteinase (MT1-MMP) is a potent regulator of cancer malignant progression through the heparin-binding EGF-like growth factor activation
- Author(s)
  Koshikawa, N & Seiki, M
- Organizer
  AACR special meeting, Tumor Invasion and Metastasis
- Place of Presentation
  San Diego, CA USA
- Data Source
  KAKENHI-PUBLICLY-23117507
[Presentation] Membrane type-1 matrix metalloproteinase promotes invasive growth signals of cancer cells by cell surface proteolysis
- Author(s)
  Koshikawa, N., Seiki, M.
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117507
[Presentation] 9. Koshikawa, N., Seiki, M.：Membrane type-1 matrix metalloproteinase promotes invasive growth signals of cancer cells by cell surface proteolysis
- Author(s)
  Koshikawa N. and Seiki M.
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25462471
[Presentation] 卵巣がんにおけるMT1-MMPによるHB-EGFの活性化についての研究
- Author(s)
  越川直彦、清木元治
- Organizer
  第21回　日本がん転移学会学術集会・総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PUBLICLY-23117507

1. SEIKI Motoharu (10154634)

# of Collaborated Projects: 3 results

# of Collaborated Products: 46 results
2. SYUUO Takuya (90399006)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. GOTO Isamu (40323638)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SAKAMOTO Takeharu (70511418)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. HOSHINO Daisuke (30571434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
6. SHUIN Taro (70128601)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. SUGIURA Kazumitsu (70335032)

# of Collaborated Projects: 2 results

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8. FUJITA Naoya (20280951)

# of Collaborated Projects: 2 results

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9. 宮園浩平 (90209908)

# of Collaborated Projects: 2 results

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10. 秋山徹 (70150745)

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11. 室井敦 (60609402)

# of Collaborated Projects: 2 results

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12. NABESHIMA Kazuki (40189189)

# of Collaborated Projects: 1 results

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13. HAMASAKI Makoto (90412600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. AOKI Mikiko (80469379)

# of Collaborated Projects: 1 results

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15. FUKADA Satoshi (80527599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. NAGANO Makoto (50572715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
17. KAMADA Masayuki (90304683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. KARASHIMA Takashi (60304672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 鈴木貴 (40114516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 川崎秀二 (10282922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 村上善則 (30182108)

# of Collaborated Projects: 1 results

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22. 滝野隆久 (40322119)

# of Collaborated Projects: 1 results

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23. 金子周一 (60185923)

# of Collaborated Projects: 1 results

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24. 山下太郎 (90377432)

# of Collaborated Projects: 1 results

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25. 石渡通徳 (30350458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
26. 中村直俊 (30554472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
27. 朝倉暢彦 (70308584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
28. 板野景子 (00608416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 宮城洋平 (00254194)

# of Collaborated Projects: 1 results

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30. OYAMA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. ICHIKAWA Kazuhisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. CHEN Cheng-hsin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. ASAHINA Yasuhiro

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# of Collaborated Products: 1 results
34. ABE Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. TOSHIMA Jiro

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36. 寺島健志

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# of Collaborated Products: 1 results
37. 大久保陽一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 渡辺守

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
39. 坂本直哉

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# of Collaborated Products: 1 results
40. 中川美奈

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 安田宏

# of Collaborated Projects: 0 results

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42. 山本博幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 齊藤宣一

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44. 福村和宏

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45. 本多政夫

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46. 山下竜也

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47. 秦裕子

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48. 井上純一郎

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49. 八尾良司

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50. 柿沼晴

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51. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 舟橋伸昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koshikawa Naohiko 越川 直彦

KOSIKAWA Naohiko 越川 直彦

KOSHIKAWA Naohiko 越川 直彦

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スプライシング異常が誘発する上皮発がんの新たな分子メカニズムの解明Principal Investigator

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Analysis of the molecular mechanism for collective invasion of squamous cell carcinoma by novel laminin fusion genePrincipal Investigator

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Analysis of cleavage fragments produced by proteolysis on cancer cell membranePrincipal Investigator

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Analysis of the molecular mechanism for formation and breakdown of biotissues by mathematical modelingPrincipal Investigator

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Development of a novel diagnostic method for bladder cancerPrincipal Investigator

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増殖因子および受容体の蛋白質プロセッシングによる制御システムの解析Principal Investigator

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Koshikawa Naohiko 越川直彦

KOSIKAWA Naohiko 越川直彦

KOSHIKAWA Naohiko 越川直彦

[Journal Article] ラミニン γ2 単鎖をバイオマーカーとした肝発がん、遠隔転移の予測を可能とする新たな診断法の構築2023