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MIYAHARA Nobuaki  宮原 信明

ORCIDConnect your ORCID iD *help
… Alternative Names

宮原 信明  ミヤハラ ノブアキ

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Researcher Number 70335610
Other IDs
Affiliation (Current) 2025: 岡山大学, 保健学域, 教授
Affiliation (based on the past Project Information) *help 2021 – 2023: 岡山大学, 保健学域, 教授
2015 – 2021: 岡山大学, 保健学研究科, 教授
2016: 岡山大学, 大学院保健学研究科, 教授
2013 – 2014: 岡山大学, 大学病院, 講師
2011 – 2012: 岡山大学, 大学病院, 助教 … More
2010 – 2011: 岡山大学, 岡山大学病院, 助教
2010: 岡山大学, 病院, 助教
2009: Okayama University, 大学病院, 助教
2008: Okayama University, 医学部・歯学部附属病院, 助教
2007: Okayama University, 医学部歯学部・附属病院, 助教 Less
Review Section/Research Field
Principal Investigator
膠原病・アレルギー・感染症内科学 / Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related
Except Principal Investigator
Respiratory organ internal medicine / Basic Section 54010:Hematology and medical oncology-related / Basic Section 55040:Respiratory surgery-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 58060:Clinical nursing-related / Basic Section 55060:Emergency medicine-related / Basic Section 58050:Fundamental of nursing-related / 膠原病・アレルギー・感染症内科学
Keywords
Principal Investigator
気道過敏性 / 気管支喘息 / 肺気腫 / COPD / 気道炎症 / 慢性閉塞性肺疾患 / 間葉系幹細胞 / CCL2 / p40 / エラスターゼ … More / Th17 / IL-17 / IL-17A / IL-23 / 特になし / bronchial asthma / 終末糖化産物受容体 / RAGE / アレルギー / 免疫寛容 / サイトカイン / T細胞 / リンパ球 / LTB4-BLT1-肥満細胞 / ロイコトリエン … More
Except Principal Investigator
COPD / 精油 / RAGE / アレルギー性気道炎症 / 好中球性気道炎症 / 気管支喘息 / 気道炎症 / 免疫学 / GVHD / NPY / 閉塞性細気管支炎 / gvhd / 肺線維化 / ダメージ関連分子パターン / アロマテラピー / 喘息 / 気道リモデリング / 呼吸リハビリテーション / テオフィリン / 貪食能 / 抗炎症作用 / アロマセラピー / ブレオマイシン処理マウス / 急性呼吸窮迫症候群 / 肺線維症 / 間質性肺炎 / 水素 / 急性呼吸促迫症候群 / 急性肺障害 / ブレオマイシンモデル / 水素ガス / 知覚障害 / カリキュラム / 生命の尊厳 / 実存的苦悩 / 人間の尊重 / カリキュラム開発 / 人間の尊厳 / 医療倫理 / ハンセン病 / RXR選択的アゴニスト / パーシャルアゴニスト / 核内受容体 / レチノイドX受容体パーシャルアゴニスト / レチノイドX受容体 / 好酸球性気道炎症 / 肺気腫 / 気道過敏症 / マウス喘息モデル / 気道過敏性 / 難治性喘息 / IL-17 / ロイコトリエン受容体拮抗薬 / 好中球エラスターゼ阻害薬 / 好中球エラスターゼ / 好中球性炎症 / アレルギー / 重症喘息 Less
  • Research Projects

    (14 results)
  • Research Products

    (115 results)
  • Co-Researchers

    (46 People)
  •  ケモカイン抑制能を強化した新規間葉系幹細胞による慢性閉塞性肺疾患の細胞療法開発Principal Investigator

    • Principal Investigator
      宮原 信明
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Okayama University
  •  Development of treatment for non-infectious respiratory complications following hematopoietic stem cell transplantation using neuropeptide NPY

    • Principal Investigator
      Maeda Yoshinobu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Okayama University
  •  Lung fibrosis suppression effect by hydrogen inhalation at ARDS subacute-chronic phase: Verification by model mouse

    • Principal Investigator
      Toshiyuki Aokage
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Okayama University
  •  COPD治療に最適なアロマセラピーを用いた呼吸リハビリテーションの構築

    • Principal Investigator
      柴倉 美砂子
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58060:Clinical nursing-related
    • Research Institution
      Okayama University
  •  喘息の気道リモデリング抑制に有用なアロマテラピー精油の探索と分子メカニズムの解明

    • Principal Investigator
      飯尾 友愛 (上野友愛)
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Okayama University
  •  Development of the novel therapy focused on damage-associated molecular patterns (DAMPs) for lung fibrosis-related diseases

    • Principal Investigator
      Toyooka Shinichi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55040:Respiratory surgery-related
    • Research Institution
      Okayama University
  •  Construction of Academic Foundations and Development of a Curriculum for the Creation of Medical Ethics of Hansen's disease

    • Principal Investigator
      KONDO Makiko
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 58050:Fundamental of nursing-related
    • Research Institution
      Kagawa Prefectural College of Health Sciences
      Okayama University
  •  Importance of IL-23 to the Development of Elastase-Induced Pulmonary Inflammation and EmphysemaPrincipal Investigator

    • Principal Investigator
      Nobuaki Miyahara
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Okayama University
  •  Effect of a retinoid X receptor partial agonist on airway inflammation, airway hyperresponsiveness, and emphysema.

    • Principal Investigator
      KANEHIRO ARIHIKO
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Okayama University
  •  the role of RAGE in COPD

    • Principal Investigator
      KOICHI WASEDA
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Okayama University
  •  The role of RAGE for allergic airway responsesPrincipal Investigator

    • Principal Investigator
      MIYAHARA NOBUAKI
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Okayama University
  •  Mechanism and therapy of neutrophilic allergic airway inflammation in severe asthma

    • Principal Investigator
      KANEHIRO ARIHIKO
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Okayama University
  •  Effects of oral tolerance in allergen-induced airway responsesPrincipal Investigator

    • Principal Investigator
      MIYAHARA Nobuaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Okayama University
  •  Role of leukotriene B4 and effector T cells in allergen-induced airway responsesPrincipal Investigator

    • Principal Investigator
      MIYAHARA Nobuaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Okayama University

All 2021 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] Allergy frontiers : Classification and Pathomechanisms2009

    • Author(s)
      Miyahara N, Gelfand EW
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Book] CD8+ T cells play a key role in development of allergic lung inflammation. Allergy frontiers : Classification and Pathomechanisms2009

    • Author(s)
      Miyahara N, Gelfand EW
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Book] Allergy frontiers : Classification and Pathomechanisms.2009

    • Author(s)
      Miyahara N. Gelfand EW
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Book] CD8+ T cells play a key role in development of allergic lung inflammation. Allergy frontiers : Classification and Pathomechanisms.2009

    • Author(s)
      Miyahara N, Gelfand EW
    • Total Pages
      12
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury2021

    • Author(s)
      Aokage Toshiyuki、Seya Mizuki、Hirayama Takahiro、Nojima Tsuyoshi、Iketani Masumi、Ishikawa Michiko、Terasaki Yasuhiro、Taniguchi Akihiko、Miyahara Nobuaki、Nakao Atsunori、Ohsawa Ikuroh、Naito Hiromichi
    • Journal Title

      BMC Pulmonary Medicine

      Volume: 21 Issue: 1 Pages: 339-339

    • DOI

      10.1186/s12890-021-01712-2

    • NAID

      120007170516

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09630, KAKENHI-PROJECT-19K09416, KAKENHI-PROJECT-20H04136, KAKENHI-PROJECT-20K08553, KAKENHI-PROJECT-21K08875, KAKENHI-PROJECT-21K11690
  • [Journal Article] The heterodimer S100A8/A9 is a potent therapeutic target for idiopathic pulmonary fibrosis2020

    • Author(s)
      Araki Kota、Kinoshita Rie、Tomonobu Nahoko、Gohara Yuma、Tomida Shuta、Takahashi Yuta、Senoo Satoru、Taniguchi Akihiko、Itano Junko、Yamamoto Ken-ichi、Murata Hitoshi、Suzawa Ken、Shien K、Yamamoto H、Okazaki M、Sugimoto S、Ichimura K、Nishibori M、Miyahara N、Toyooka S、Sakaguchi Masakiyo
    • Journal Title

      Journal of Molecular Medicine

      Volume: 99 Issue: 1 Pages: 131-145

    • DOI

      10.1007/s00109-020-02001-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19H03746, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
  • [Journal Article] Severe asthma concomitant with allergic bronchopulmonary aspergillosis successfully treated with mepolizumab2018

    • Author(s)
      Oda N, Miyahara N, Senoo S, Itano J, Taniguchi A, Morichika D, Fujii U, Maeda Y, Kiura K, Kanehiro A.
    • Journal Title

      Allergol. Int.

      Volume: 67 Issue: 4 Pages: 521-523

    • DOI

      10.1016/j.alit.2018.03.004

    • ISSN
      1323-8930, 1440-1592
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Journal Article] Pneumocystis Pneumonia Concomitant with Ectopic ACTH Syndrome Caused by a Large Cell Neuroendocrine Carcinoma of the Thymus2017

    • Author(s)
      Oda N, Miyahara N, Tabata M, Minami D, Ninomiya K, Kanehiro A, Komatsubara M, Inagaki K, Tanimoto M, Kiura K.
    • Journal Title

      Intern. Med.

      Volume: 56 Issue: 5 Pages: 551-555

    • DOI

      10.2169/internalmedicine.56.7655

    • NAID

      130005399422

    • ISSN
      0918-2918, 1349-7235
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Journal Article] Effect of a retinoid X receptor partial agonist on airway inflammation and hyperresponsiveness in a murine model of asthma.2017

    • Author(s)
      Fujii U, Miyahara N, Taniguchi A, Oda N, Morichika D, Murakami E, Nakayama H, Waseda K, Kataoka M, Kakuta H, Tanimoto M, Kanehiro A.
    • Journal Title

      Respir Res

      Volume: 18:23 Issue: 1 Pages: 1-10

    • DOI

      10.1186/s12931-017-0507-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Journal Article] Long-term effects of beta-blocker use on lung function in Japanese patients with chronic obstructive pulmonary disease.2017

    • Author(s)
      Oda N, Miyahara N, Ichikawa H, Tanimoto Y, Kajimoto K, Sakugawa M, Kawai H, Taniguchi A, Morichika D, Tanimoto M, Kanehiro A, Kiura K.
    • Journal Title

      Int J COPD

      Volume: 12 Pages: 1119-1124

    • DOI

      10.2147/copd.s133071

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Journal Article] Protective Effects of Bisoprolol against Acute Exacerbation in Moderate-to-Severe Chronic Obstructive Pulmonary Disease2017

    • Author(s)
      Taniguchi A, Miyahara N, Oda N, Morichika D, Ichihara E, Oze I, Tanimoto Y, Ichikawa H, Fujii U, Tanimoto M, Kanehiro A, Kiura K.
    • Journal Title

      Acta Medica Okayama

      Volume: 71 Issue: 5 Pages: 453-457

    • DOI

      10.18926/AMO/55446

    • NAID

      120006352368

    • URL

      https://ousar.lib.okayama-u.ac.jp/55446

    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Journal Article] IL-23 is essential for the development of elastase-induced pulmonary inflammation and emphysema.2016

    • Author(s)
      Fujii U, Miyahara N,Taniguchi A, Waseda K, Morichika D, Kurimoto E, Koga H, Kataoka M, Gelfand EW, Cua DJ, Yoshimura A, Tanimoto M, Kanehiro A
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 55 Issue: 5 Pages: 697-707

    • DOI

      10.1165/rcmb.2016-0015oc

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09221, KAKENHI-PROJECT-26461189
  • [Journal Article] Heerfordt's Syndrome Associated with a High Fever and Elevation of TNF-α.2016

    • Author(s)
      Makimoto G, Miyahara N, Yoshikawa M, Taniguchi A, Kanehiro A, Tanimoto M, Kiura K.
    • Journal Title

      Acta Med Okayama

      Volume: 70 Pages: 273-277

    • NAID

      120005828915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Journal Article] Emphysema requires the receptor for advanced glycation end products triggering on structural cells.2015

    • Author(s)
      Waseda K, Miyahara N, Taniguchi A, Kurimoto E, Ikeda G, Koga H, Fujii U, Yamamoto Y, Gelfand EW, Yamamoto H, Tanimoto M, Kanehiro A.
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 52(4) Issue: 4 Pages: 482-491

    • DOI

      10.1165/rcmb.2014-0027oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590375, KAKENHI-PROJECT-25461335, KAKENHI-PROJECT-26461189, KAKENHI-PROJECT-25860644
  • [Journal Article] Contrasting roles for the receptor for advanced glycation end-products on structural cells in allergic airway inflammation vs. airway hyperresponsiveness.2015

    • Author(s)
      Taniguchi A, Miyahara N, Waseda K, Kurimoto E, Fujii U, Tanimoto Y, Kataoka M, Yamamoto Y, Gelfand EW, Yamamoto H, Tanimoto M, Kanehiro A.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol

      Volume: 309 Issue: 8 Pages: L789-L800

    • DOI

      10.1152/ajplung.00087.2015

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461189, KAKENHI-PROJECT-25461335
  • [Journal Article] Effect of a Cysteinyl Leukotriene Receptor Antagonist on Experimental Emphysema and Asthma Combined with Emphysema2014

    • Author(s)
      Ikeda G, Kanehiro A, et al
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 50 Issue: 1 Pages: 18-29

    • DOI

      10.1165/rcmb.2012-0418oc

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22591092, KAKENHI-PROJECT-25860644, KAKENHI-PROJECT-26461189
  • [Journal Article] Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway response2013

    • Author(s)
      Hikari Koga
    • Journal Title

      Respiratory Research

      Volume: 14 Issue: 1 Pages: 8-8

    • DOI

      10.1186/1465-9921-14-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590526, KAKENHI-PROJECT-22591092, KAKENHI-PROJECT-25860644
  • [Journal Article] IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice2013

    • Author(s)
      Etsuko Kurimoto
    • Journal Title

      Respiratory Research

      Volume: 14 Issue: 1 Pages: 5-5

    • DOI

      10.1186/1465-9921-14-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590526, KAKENHI-PROJECT-22591092, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-25860644
  • [Journal Article] A definite case of (L)-carbocisteine-induced pneumonia with CATCH22 syndrome2013

    • Author(s)
      Kudo K, Miyahara N, et al
    • Journal Title

      Intern Med

      Volume: 52 Pages: 97-100

    • NAID

      130003365553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591092
  • [Journal Article] Whole Body Plethysmograph法を用いたマウスアレルギー性鼻炎モデルにおける抗原特異的即時相、遅発相および抗原非特異的鼻過敏性反応の測定2011

    • Author(s)
      宮原聡子、宮原信明、松原茂樹
    • Journal Title

      日本薬理学会雑誌

      Volume: 137 Pages: 141-145

    • NAID

      10029417403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] マウスアレルギー性鼻炎における抗原特異的即時相,遅発相および抗原非特異的過敏性反応の測定と鼻反応におけるIgE,肥満細胞,IL-13の役割2011

    • Author(s)
      宮原聡子、松原茂樹、宮原信明
    • Journal Title

      アレルギーの臨床

      Volume: 31 Pages: 986-993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Measurement of early-phase, late-phase, and nonspecific nasal responses in allergic rhinitis mouse by whole body plethysmography2011

    • Author(s)
      Miyahara S, Miyahara N, et al
    • Journal Title

      Nihon Yakurigaku Zasshi

      Volume: 137 Pages: 141-145

    • NAID

      10029417403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591092
  • [Journal Article] Successful extracorporeal life support for life-threatening hypercapnia with bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation2011

    • Author(s)
      Waseda K, Tanimoto Y, Ichiba S, Miyahara N, Murakami T, Ochi N, Terado M, Nagano O, Maeda Y, Kanehiro A, Ujike Y, Tanimoto M
    • Journal Title

      Acta Med Okayama

      Volume: 65 Pages: 403-406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] WholeBody Plethysmograph法を用いたマウスアレルギー性鼻炎モデルにおける抗原特異的即時相、遅発相および抗原非特異的鼻過敏性反応の測定2011

    • Author(s)
      宮原聡子、宮原信明、松原茂樹
    • Journal Title

      日本薬理学会雑誌

      Volume: 137(3) Pages: 141-145

    • NAID

      10029417403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] マウスアレルギー性鼻炎における抗原特異的即時相,遅発相および抗原非特異的過敏性反応の測定と鼻反応におけるIgE,肥満細胞, IL-13の役割2011

    • Author(s)
      宮原聡子、松原茂樹、宮原信明
    • Journal Title

      アレルギーの臨床

      Volume: 31(11) Pages: 986-993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Requirement for CCR5 in the development of allergen-induced airway hyperresponsiveness and inflammation2011

    • Author(s)
      Fuchimoto Y, Kanehiro A, Miyahara N, Koga H, Ikeda G, Waseda K, Tanimoto Y, Ueha S, Kataoka M, Gelfand EW, Tanimoto M
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 45 Pages: 1248-1255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Blocking the leukotriene B4 receptor 1 inhibits late phase airway responses in established disease2011

    • Author(s)
      Waseda K, Miyahara N, Kanehiro A, Ikeda G, Koga H, Fuchimoto Y, Kurimoto E, Tanimoto Y, Kataoka M, Tanimoto M, Gelfand EW
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 45 Pages: 851-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Requirement for CCR5 in the development of allergen-induced airway hyperresponsiveness and inflammation2011

    • Author(s)
      Fuchimoto Y, Kanehiro A, Miyahara N, Koga H, Ikeda G, Waseda K, Tanimoto Y, Ueha S, Kataoka M, Gelfand EW, Tanimoto M
    • Journal Title

      Am J Respir Cell MolBiol

      Volume: 45(6) Pages: 1248-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Churg-Strauss Syndrome with necrosis of toe tips2011

    • Author(s)
      Waseda K, Tanimoto Y, Hasegawa K, Miyahara N, Nojima D, Ikeda I, Kanehiro A, Okada C, Kimata Y, Tanimoto M
    • Journal Title

      Acta Med Okayama

      Volume: 65 Pages: 215-218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation. Br J Pharmacol. 2010 ; 160 : 1399-4072010

    • Author(s)
      Takeda K, Shiraishi Y, Matsubara S, Miyahara N, Matsuda H, Okamoto M, Joetham A, Gelfand EW.
    • Journal Title

      Br J Pharmacol

      Volume: 160 Pages: 1399-1407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation2010

    • Author(s)
      Takeda K, Miyahara N, et al
    • Journal Title

      Br J Pharmacol

      Volume: 160 Issue: 6 Pages: 1399-407

    • DOI

      10.1111/j.1476-5381.2010.00797.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591092
  • [Journal Article] アレルギー疾患と脂質メディエーター-ロイコトリエンB_42010

    • Author(s)
      宮原信明
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 54 Pages: 51-57

    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Plasticity of Invariant NKT Cell Regulation of Allergic Airway Disease Is Dependent on IFN-g Production2010

    • Author(s)
      Matsuda H, Takeda K, Koya T, Okamoto M, Shiraishi Y, Miyahara N, Dakhama A, Matsuda JL, Gapin L, Gelfand EW
    • Journal Title

      J Immunol

      Volume: 185 Pages: 253-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Plasticity of Invariant NKT Cell Regulation of Allergic Airway Disease Is Dependent on IFN-g Production.2010

    • Author(s)
      Matsuda H, Takeda K, Koya T, Okamoto M, Shiraishi Y, Miyahara N, Dakhama A, Matsuda JL, Gapin L, Gelfand EW.
    • Journal Title

      J Immunol.2010 ; 185 : 253-62

      Volume: 185 Pages: 253-262

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Plasticity of Invariant NKT Cell Regulation of Allergic Airway Disease Is Dependent on IFN-γ Production2010

    • Author(s)
      Matsuda H, Miyahara N
    • Journal Title

      J Immunol

      Volume: 185 Pages: 153-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591092
  • [Journal Article] Plasticity of invariant NKT cell regulation of allergic airway disease is dependent on IFN-gamma production2010

    • Author(s)
      Matsuda H, Miyahara N, et al
    • Journal Title

      J Immunol

      Volume: 185 Issue: 1 Pages: 253-262

    • DOI

      10.4049/jimmunol.0902301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591092
  • [Journal Article] Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation2010

    • Author(s)
      Takeda K, Shiraishi Y, Matsubara S, Miyahara N, Matsuda H, Okamoto M, Joetham A, Gelfand EW
    • Journal Title

      Br J Pharmacol

      Volume: 160 Pages: 1399-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Experimental pulmonary granuloma mimicking sarcoidosis induced by Propionibacterium acnes in mice. Acta Med Okayama. 2010 ; 64 : 75-83.2010

    • Author(s)
      Iio K, Iio TU, Okui Y, Ichikawa H, Tanimoto Y, Miyahara N, Kanehiro A, Tanimoto M, Nakata Y, Kataoka M
    • Journal Title

      Acta Med Okayama

      Volume: 64 Pages: 75-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Effects of combination therapy with montelukast and carbocysteine in allergen-induced airway hyperresponsiveness and airway inflammation2010

    • Author(s)
      Takeda K, Miyahara N
    • Journal Title

      Br J Pharmacol

      Volume: 160 Pages: 1399-1407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591092
  • [Journal Article] アレルギー疾患と脂質メディエーター。ロコイトリエンB42010

    • Author(s)
      宮原信明
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 54(1) Pages: 51-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Leukotriene B4 Release from Mast Cells in IgE-Mediated Airway Hyperresponsiveness and Inflammation2009

    • Author(s)
      Miyahara N
    • Journal Title

      Am J Respir Cell Mol Biol. 40

      Pages: 672-682

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Leukotriene B4 Release from Mast Cells in IgE-Mediated Airway Hyperresponsiveness and Inflammation2009

    • Author(s)
      Miyahara N, Ohnishi H, Miyahara S, Takeda K, Matsubara S, Matsuda H, Okamoto M, Loader JE, Joetham A, Tanimoto M, Dakhama A, Gelfand EW
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 40 Pages: 672-82

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Gelfand EW Mitogen-activated protein kinase/extracellular signal-regulated kinase kinases2009

    • Author(s)
      Ohnishi H, Takeda K, Domenico J, Lucas JJ, Miyahara N, Swasy CH, Dakhama A
    • Journal Title

      1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inflammation. J Allergy Clin Immunol 123

      Pages: 249-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation2009

    • Author(s)
      Takeda K, Dow SW, Miyahara N, Kodama T, Koya T, Taube C, Joetham A, Park JW, Dakhama A, Kedl RM, Gelfand EW
    • Journal Title

      J Immunol

      Volume: 183 Pages: 181-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Mitogen-activated protein kinase/extracellular signal-regulated kinase kinases 1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inflammation2009

    • Author(s)
      Ohnishi H, Takeda K, Domenico J, Lucas JJ, Miyahara N, Swasy CH, Dakhama A, Gelfand EW
    • Journal Title

      J Allergy Clin Immunol.

      Volume: 123 Pages: 249-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Journal Article] Evidence That CD8+ Dendritic Cells Enable the Development of {gamma}{delta} T Cells That Modulate Airway2008

    • Author(s)
      Cook L, Miyahara N, Jin N, Wands JM, Taube C, Roark CL, Potter TA, Gelfand EW, O'Brien RL, Born WK
    • Journal Title

      Hyperresponsiveness. J Immunol 181

      Pages: 309-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] EW. Leukotriene B4 receptor-1 (BLT1) expression on dendritic cells is required for the development of Th2 responses and allergen-induced airway2008

    • Author(s)
      Miyahara N, Ohnishi H, Matsuda H, Miyahara S, Takeda K, Koya T, Matsubara S, Okamoto M, Dakhama A, Haribabu B, Gelfand EW
    • Journal Title

      hyperresponsiveness.J. Jmmunol 181

      Pages: 1170-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Contribution of allergen-specific and nonspecific nasal responses to early-phase and late-phase nasal responses2008

    • Author(s)
      Miyahara s, Miyahara N, 他6名
    • Journal Title

      J Allergy Clin Immunol. 121

      Pages: 718-724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Leukotriene B4 receptor-1 (BLT1) expression on dendritic cells is required for the development of Th2 responses and allergen-induced airway hyperresponsiveness2008

    • Author(s)
      Miyahara N, 他10名
    • Journal Title

      J Immunol. 181

      Pages: 1170-1178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Naturally-Occnrring Lnng CD4+CD25+ T-Cell Regulation of Airway Allergic Responses Depends on IL-10 Induction of TGF-b2007

    • Author(s)
      Joetham A, Takada K, Taube C, Miyahara N, 他5名
    • Journal Title

      J Immunol 178

      Pages: 1433-1442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation.2007

    • Author(s)
      Kitamura K, Takeda K, Koya T, Miyahara N, 他7名
    • Journal Title

      J Immunol 178

      Pages: 480-488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells2007

    • Author(s)
      Matsubara S, Takeda K, Kodama T, Joetham A, Miyahara N, 他5名
    • Journal Title

      Am J Respir Cell Mol Biol. 36

      Pages: 324-332

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] IFN-[gamma] Production During Initial Infection Determines the Outcome of Re-infection with RSV.2007

    • Author(s)
      Lee YM, Miyahara N, 他7名
    • Journal Title

      Am J Respir Crit Care Med. 177

      Pages: 208-218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Airway Hyperresponsiveness through Synergy of {gamma} {delta} T Cells and NKT Cells2007

    • Author(s)
      Jin N, Miyahara N, 他8名
    • Journal Title

      J Immunol 179

      Pages: 2961-2968

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Arhgefl is Required by T cells for the Development of Airway Hyperreactivity and Inflammation.2007

    • Author(s)
      Brown JP, Taube C, Miyahara N, 他3名
    • Journal Title

      Am J Respir Crit Care Med. 176

      Pages: 10-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] IL-10-treated dendritic cells decrease airway hyperresponsiveness and airway inflammation.2007

    • Author(s)
      Koya T, Matsuda H, Takeda K, Matsubara S, Miyahara N, 他3名
    • Journal Title

      J Allergy Clin Immunol. 119

      Pages: 1241-1250

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Activation of naturally occurring lung CD4+CD25+ regulatory T cells requires CD8 and MHC I interaction2007

    • Author(s)
      Joetham A, Takeda K, Miyahara N, 他5名
    • Journal Title

      Proc NatI Acad Sci U S A. 104

      Pages: 15057-15062

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] アレルギー性気道炎症における樹状細胞および脂質メデイエーターの役割の検討2007

    • Author(s)
      宮原信明
    • Journal Title

      アレルギア 36

      Pages: 65-67

    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] CD8+ T Cell-Mediated Airway Hyperresponsiveness and Inflammation Is Dependent on CD4+IL-4+ T Cells2007

    • Author(s)
      Koya T, Miyahara N, 他7名
    • Journal Title

      J Immunol 179

      Pages: 2787-2796

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Leukotriene B4 Release from Mast Cells in IgE-Mediated Airway Hyperresponsiveness and Inflammation.

    • Author(s)
      Miyahara N, 他11名
    • Journal Title

      Am J Respir Cell Mol Biol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Journal Article] Leukotriene B4 Release from Mast Cells in IgE-Mediated Airway

    • Author(s)
      Miyahara N, Ohnishi H, Miyahara S, Takeda K, Matsubara S, Matsuda H, Okamoto M, Loader JE, Joetham A, Tanimoto M, Dakhama A, Gelfand EW
    • Journal Title

      Hyperresponsiveness and Inflammation. Am J Respir Cell Mol Biol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Patent] 炎症性呼吸器疾患の予防又は治療用医薬組成物2016

    • Inventor(s)
      金廣有彦、加来田博貴、宮原信明、藤井詩子、森近大介、小田尚廣
    • Industrial Property Rights Holder
      金廣有彦、加来田博貴、宮原信明、藤井詩子、森近大介、小田尚廣
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016
    • Acquisition Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] Effect of a Retinoid X Receptor partial agonist on the development of emphysema and airway inflammation in a murine model of emphysema.2017

    • Author(s)
      Morichika D, Kanehiro A, Kakuta H, Taniguchi A, Fujii U, Oda N, Miyahara N, Kiura K, Tanimoto M.
    • Organizer
      Annual International Conference of the American Thoracic Society 2017 International Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] The Role of Retinoid X Receptor in allergen-induced Airway Inflammation in Mice.2016

    • Author(s)
      Fujii U, Kanehiro A, Kakuta H, Taniguchi A, Oda N, Morichika M, Ikeda G, Koga H, Waseda K, Kurimoto E, Miyahara N, Kataoka M, Tanimoto M.
    • Organizer
      65th Annual meeting of Japanese Society of Allergology, 2016. (English oral session)
    • Place of Presentation
      東京
    • Year and Date
      2016-06-17
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] Treatment with Retinoid X Receptor partial agonist attenuates eosinophilic inflammation and airway hyperresponsiveness.2016

    • Author(s)
      Fujii U, A. Kanehiro A, Taniguchi A, Oda N, Morichika D, Waseda K, Murakami E, Nakayama M, Kataoka M, Kakuta H, Miyahara N, Kiura K, Tanimoto M.
    • Organizer
      Annual International Conference of the American Thoracic Society International Conference. 2016.
    • Place of Presentation
      サンフランシスコ
    • Year and Date
      2016-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] IL-23 is essential to the development of elastase-induced pulmonary inflammation and emphysema.2016

    • Author(s)
      Fujii U, Miyahara N, Taniguchi A, Morichika D, Oda N, Murakami E, Nakayama M, Kataoka M, Yoshimura A, Gelfand EW, Tanimoto M, Kanehiro A.
    • Organizer
      European Respiratory Society Annual Congress. 2016.
    • Place of Presentation
      ロンドン
    • Year and Date
      2016-09-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] Endobronchial ultrasound-guided transbronchial needle aspiration of hilar and mediastinal lymph nodes detected on 18F-fluoradeoxyglucose positoron emission tomography/computed tomography.2016

    • Author(s)
      Minami D, Takigawa Y, Kato T, Ninomiya T, Kubo K, Ohashi K, Hotta T, Shibayama N, Miyahara N, Tabata A, Kanehiro A, Tanimoto M, Kiura K.
    • Organizer
      Annual International Conference of the American Thoracic Society International Conference. 2016.
    • Place of Presentation
      サンフランシスコ
    • Year and Date
      2016-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] IL-23 is Essential to the Development of Elastase-induced Pulmonary Inflammation and Emphysema.2016

    • Author(s)
      Fujii U, Miyahara N, Taniguchi A, Waseda K, Morichika D, Kurimoto E, Koga H, Kataoka M, Gelfand EW, Cua DJ, Yoshimura A, Tanimoto M, Kanehiro A.
    • Organizer
      56th Annual meeting of Japanese Respiratory Society, 2016. (English oral session)
    • Place of Presentation
      京都
    • Year and Date
      2016-04-08
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] IL-23 is Essential to the Development of Elastase-induced Pulmonary Inflammation and Emphysema2016

    • Author(s)
      Utako Fujii, Nobuaki Miyahara, Akihiko Taniguchi, Koichi Waseda, Daisuke Morichika, Etsuko Kurimoto, Naohiro Oda, Hikari Koga, Mikio Kataoka, Akihiko Yoshimura, Mitsune Tanimoto, Arihiko Kanehiro
    • Organizer
      The 56th Annual Meeting of Japanese Respiratory Society
    • Place of Presentation
      京都
    • Year and Date
      2016-04-09
    • Data Source
      KAKENHI-PROJECT-15K09221
  • [Presentation] Effect of Retinoid X Receptor partial agonist on airway inflammation and hyperresponsiveness.2015

    • Author(s)
      Fujii U, A. Kanehiro A, Taniguchi A, Morichika D, Waseda K, Murakami E, Nakayama M, Kataoka M, Kakuta H, Miyahara N, Tanimoto M
    • Organizer
      European Respiratory Society Annual Congress 2015.
    • Place of Presentation
      Amsterdam NETHERLANDS
    • Year and Date
      2015-09-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] Importance of IL-23 to the development of elastase-induced pulmonary inflammation and emphysema.2015

    • Author(s)
      Fujii U, Miyahara N, Taniguchi A, Kawano K, Waseda K, Morichika D, Koga H, Kataoka M, Tanimoto M, Yoshimura A, Kanehiro A.
    • Organizer
      Annual International Conference of the American Thoracic Society International Conference 2015.
    • Place of Presentation
      Denver CO USA
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] Allergen-induced airway inflammation requires the receptor for advanced glycation end products triggering on airway structural cells2014

    • Author(s)
      A.Taniguchi, N.Miyahara, A.Kanehiro, K.Waseda, E.Kurimoto, U.Fujii, Y.Tanimoto, M.Kataoka, Y. Yamamoto, E.W. Gelfand , H. Yamamoto, M.Tanimoto.
    • Organizer
      Annual meeting of American Thoracic Society 2014
    • Place of Presentation
      サンディエゴ、USA
    • Data Source
      KAKENHI-PROJECT-24591463
  • [Presentation] マウスアレルギー性気道炎症モデルにおける終末糖化産物(RAGE)の役割2014

    • Author(s)
      谷口 暁彦,宮原 信明,金廣 有彦,早稲田 公一,栗本 悦子,能島 大輔,谷本 安,片岡幹男,木浦勝行,山本 靖彦,山本 博,谷本 光音
    • Organizer
      第54回日本呼吸器学会学術講演会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-24591463
  • [Presentation] Essential Role of the Receptor for Advanced Glycation End-Products to the Development of Allergic Airway Inflammation2013

    • Author(s)
      A.Taniguchi, N.Miyahara, A.Kanehiro, K.Waseda, E.Kurimoto, Y.Tanimoto, M.Kataoka, Y. Yamamoto, H. Yamamoto, E.W. Gelfand , K. Kiura, M.Tanimoto.
    • Organizer
      第53回日本呼吸器学会学術講演会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-24591463
  • [Presentation] アレルギー性気道炎症における終末糖化産物受容体(RAGE)の役割2012

    • Author(s)
      谷口 暁彦,宮原 信明,金廣 有彦,早稲田 公一,栗本 悦子,能島 大輔,谷本 安,片岡幹男,木浦 勝行,山本 靖彦,山本 博,谷本 光音
    • Organizer
      第62回日本アレルギー学会秋季学術大会
    • Place of Presentation
      大阪国際会議場
    • Data Source
      KAKENHI-PROJECT-24591463
  • [Presentation] C-jun N-terminal kinase mediates glucocorticoid-induced TNF receptor family-related protein (GTIR)-induced loss of suppression by naturally occurring T regulatory cells2011

    • Author(s)
      Joetham A, Ohnishi H, Takeda K, Matsubara S, Miyahara N, Schedel M, Domenico J, Gelfand EWM
    • Organizer
      ATS International Conference
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] オキサリプラチンアレルギーを獲得した大腸癌患者に対する減感作によるオキサリプラチン再投与の検討2011

    • Author(s)
      谷本安, 谷口暁彦, 能島大輔, 栗本悦子, 早稲田公一, 古賀光, 宮原信明, 木浦勝行, 宗田良, 片岡幹男, 谷本光音
    • Organizer
      第61回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] C-jun N-terminal kinase mediates glucocorticoid-induced TNF receptor family-related protein(GTIR)-induced loss of suppression by naturally occurring T regulatory cells2011

    • Author(s)
      Joetham A, Ohnishi H, Takeda K, Matsubara S, Miyahara N, Schedel M, Domenico J, Gelfand EW
    • Organizer
      ATS International Conference
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] オマリズマブ投与により著明な改善を認めた好酸球性副鼻腔炎合併難治性喘息の1例2011

    • Author(s)
      谷口暁彦, 金廣有彦, 宮原信明, 能島大輔, 栗本悦子, 早稲田公一, 谷本安, 片岡幹男, 木浦勝行, 岡野光博, 谷本光音
    • Organizer
      第61回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Synergistic effects of CD4+ and CD8+ T cells for the full development of allergen-induced airway hyperresponsiveness requires leukotriene B4 receptor-1 expression2011

    • Author(s)
      Ohnishi H, Miyahara N, Takeda K, Joetham A, Yokoyama A, Gelfand EW
    • Organizer
      ATS International Conference
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Importance of receptor for advanced glycation end products(RAGE) to the development of elastase-induced pulmonary inflammation and emphysema in mice2011

    • Author(s)
      Waseda K, Miyahara N, Kanehiro A, Ikeda G, Koga H, Kurimoto E, Fuchimoto E, Taniguchi A, Tanimoto Y, Kataoka M, Gelfand EW, Tanimoto M
    • Organizer
      ATS International Conference
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Synergistic effects of CD4+ and CD8+ T cells for the full development of allergen-induced airway hyperresponsiveness requires leukotriene B4 receptor-12011

    • Author(s)
      Ohnishi H, Miyahara Y, Takeda K, Joetham A, Yokoyama A, Gelfand EW
    • Organizer
      ATS International Conference
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] 吸入ステロイド治療を継続中の喘息患者の吸気流速と背景因子の関連性調査中国、四国地区多施設研究2011

    • Author(s)
      尾長谷靖, 金廣有彦, 谷本安, 宮原信明, 谷本光音, 岡三喜男, 江田良輔, 窪田哲也, 横山彰仁, 若林規良, 竹山博泰, 岡田千春, 木村五郎, 宗田良, 高橋清
    • Organizer
      第23回日本アレルギー学会春季臨床大会
    • Place of Presentation
      千葉
    • Year and Date
      2011-05-14
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Importance of receptor for advanced glycation end products (RAGE) to the development of elastase-induced pulmonary inflammation and emphysema in mice2011

    • Author(s)
      Waseda K, Miyahara N, Kanehiro A, Ikeda G, Koga H, Kurimoto E, Fuchimoto E, Taniguchi A, Tanimoto Y, Kataoka M, (Gelfand EW), Tanimoto M
    • Organizer
      ATS International Conference
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2011-05-18
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] ヒト好塩基球の抗原提示能に関する検討-IL-3で活性化された好塩基球はHLA-DRを発現する2010

    • Author(s)
      能島大輔, 谷本安, 栗本悦子, 早稲田公一, 宮原信明, 金廣有彦, 岸本卓巳, 片岡幹男, 高橋清, 谷本光音
    • Organizer
      第60回日本アレルギー学会秋期学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-25
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] アレルギー誘発性気道過敏性亢進におけるCD4T細胞、CD8T細胞両方のBLT1発現の必要2010

    • Author(s)
      大西広志, 宮原信明, 武田勝行, 横山彰仁, Celfand EW
    • Organizer
      第60回日本アレルギー学会秋期学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-25
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Blockade of the leukotriene B4 receptor 1 suppresses allergen-induced late phase airway development of AHR and inflammation in established asthma2010

    • Author(s)
      Waseda K, Miyahara N, Kanehiro A, Ikeda G, Fuchimoto Y, Koga H, Kurimoto E, Tanimoto Y, Kataoka M, Yanimoto M, Gelfand EW
    • Organizer
      ATS International Conference
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-04-14
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] アレルギー性気道反応における経口免疫寛容の効果2010

    • Author(s)
      宮原信明, 武田勝行, 宮原聡子, 早稲田公一, 栗本悦子, 池田元洋, 古賀光, 谷口暁彦, 能島大輔, 渊本康子, 谷本安, 金廣有彦, 片岡幹男, Gelfand EW, 谷本光音
    • Organizer
      第60回日本アレルギー学会秋期学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-25
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Effect of cysteiny leukotriene receptor antagonist on airway hyperresponsiveness, airway inhlammation, and the development of emphysematous change in a murine model of COPD combined with bronchial asthma2010

    • Author(s)
      Ikeda G, Kanehiro A, Miyahara N, Koga H, Fuchimoto Y, Waseda K, Kurimoto E, Ono K, Hirano A, Tanimoto Y, Kataoka M, Tanimoto M
    • Organizer
      ATS International Conference
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-04-14
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] アレルギー誘発性気道過敏性亢進におけるCD4T細胞、CD8T細胞両方のBLT1発現の必要性2010

    • Author(s)
      大西広志, 宮原信明, 武田勝行, 横山彰仁, Gelfand EW
    • Organizer
      第60回日本アレルギー学会秋期学術大会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-25
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Requirement for Leukotriene B4 in Mast-cell independent and dependent allergic airwayresponses2009

    • Author(s)
      Nobuaki Miyahara
    • Organizer
      第49回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2009-06-14
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] ワークショック:アレルギー性疾患と脂質メディエーター-最近の知見-ロイコトリエンB42009

    • Author(s)
      宮原信明
    • Organizer
      第51回日本アレルギー学会秋季学術大会
    • Place of Presentation
      秋田
    • Year and Date
      2009-10-31
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Requirement for Leukotriene B4 in Mast-cell independent and dependent allergic airway responses2009

    • Author(s)
      Nobuaki Miyahara
    • Organizer
      第49回日本呼吸器学会学術講演会
    • Place of Presentation
      東京
    • Year and Date
      2009-06-12
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] ワークショック : アレルギー性疾患と脂質メディエーター -最近の知見-ロイコトリエンB42009

    • Author(s)
      宮原信明
    • Organizer
      第59回日本アレルギー学会秋季学術大会
    • Place of Presentation
      秋田
    • Data Source
      KAKENHI-PROJECT-21591281
  • [Presentation] Requirement for Leukotriene B4 Release from Mast Cells in the Development of IgE-Mediated Airway Hyperresponsiveness2008

    • Author(s)
      N. Miyahara, 他10名
    • Organizer
      104th Annual Meeting of American Thoracic Society
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2008-05-18
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Confirmation of the Essential Role of Leukotriene B4 in the Development of Airway Hyperresponsiveness Using Leukotriene A4 Hydrolase-Deficient Mice2008

    • Author(s)
      N. Miyahara
    • Organizer
      第58回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-27
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Requirement for Leukotriene B4 Release from Mast Cells in the Development of IgE-Mediated Airway Hyperresponsiveness2008

    • Author(s)
      N. Miyahara
    • Organizer
      Hyperresponsiveness, 104th Annual Meeting of American Thoracic Society
    • Place of Presentation
      Totonto, Canada
    • Year and Date
      2008-05-18
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Additive Effects of Montelukast and Carbocysteine on Airway Hyperresponsive2007

    • Author(s)
      K. Takeda, S. Matsubara, N. Miyahara, 他6名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Memory CD8+ T Cell-Mediated Airway Hyperresponsiveness and Allergic Airway I2007

    • Author(s)
      H. Ohnishi, N. Miyahara, 他8名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] CD8T細胞およびロイコトリエンB4受容体の気道過敏性における役割の検討2007

    • Author(s)
      宮原信明, 他9名
    • Organizer
      日本アレルギー学会春季臨床大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-06-11
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] 樹状細胞およびロイコトリエンB4受容体のアレルギー性気道反応における役割の検討2007

    • Author(s)
      宮原信明, 他13名
    • Organizer
      日本アレルギー学会秋季学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-11-01
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] 樹状細胞およびロイコトリエンB4受容体のアレルギー性気道反応における役割の検討2007

    • Author(s)
      宮原信明, 他13名
    • Organizer
      日本アレルギー学会春季臨床大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-11-01
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Activation of Invariant NKT Cells with Ligand Loaded Bone Marrow Derived Den2007

    • Author(s)
      H. Matsuda, T. Koya, k. Takeda, M. Miyahara, 他4名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Naturally Occurring CD4+CD25+ Regulatory T Cells Suppress CD8+ T Cell-Mediat2007

    • Author(s)
      A.A. Joetham, K. Takeda, S. Matsubara, N. Miyahara, 他4名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] The Role of Notch Signaling in Effector Memory CD8+ T Cell Development of Ai2007

    • Author(s)
      M. Okamoto, K. Takeda, H. Onishi, H. Matsuda, s Matsubara, N. Miyahara, 他2名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Role of FcgammaRIII in the Maintenance Phase of Allergen-Induced Airway Hype2007

    • Author(s)
      K. Takeda, A. Hirano, N. Miyahara, 他10名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Anti-IgE Prevents Respiratory Syncytial Virus (RSV)-Specific IgE-Mediated Mo2007

    • Author(s)
      A. Dakhama, Y. M. Lee, N. Miyahara, 他4名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-22
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Miyahara. Memory CD8+ T Cell-Mediated Airway Hyperresponsiveness and Allergic Airway Inflammation by Upregulating the Leukotriene B4 Receptor, BLT12007

    • Author(s)
      H. Ohnishi, N. Miyahara
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] TRole of IFN-gamma in the Development of Airway Hyperresponsiveness (AHR) Fo2007

    • Author(s)
      Y. M. Lee, N. Miyahara, 他5名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-22
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Timing of Allergen Sensitization with Adoptively Transferred Dendritic Cell2007

    • Author(s)
      T. Koya, K. Takeda, H. Matsuda, S. Matsubara, N Miyahara, 他4名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Requirement for the Leukotriene B4 Receptor-1 (BLT1) on Dendritic Cells in the Development of Allergen-Induced Airway Hyperresponsiveness2007

    • Author(s)
      N. Miyahara
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-22
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] Requirement for the Leukotriene B4 Receptor-1 (BLTI) on Dendritic Cells in t2007

    • Author(s)
      N. Miyahara, 他10名
    • Organizer
      103th Annual Meeting of American Thoracic Society
    • Place of Presentation
      San Francisco
    • Year and Date
      2007-05-22
    • Data Source
      KAKENHI-PROJECT-19599015
  • [Presentation] マウスアレルギー性気道炎症モデルにおける終末糖化産物受容体(RAGE)の役割

    • Author(s)
      谷口 暁彦,宮原 信明,金廣 有彦,早稲田 公一,栗本 悦子,能島 大輔,谷本 安,片岡幹男,木浦勝行,山本 靖彦,山本 博,谷本 光音
    • Organizer
      第54回日本呼吸器学会学術講演会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2014-04-25 – 2014-04-27
    • Data Source
      KAKENHI-PROJECT-24591463
  • [Presentation] Allergen-induced airway inflammation requires the receptor for advanced glycation end-products triggering on airway structural cells

    • Author(s)
      Taniguchi Y, Miyahara N, Kanehiro A, Waseda K, Kurimoro E, Fujii U, Tanimoto Y, Kataoka M, Yamamoto Y, Gelfand EW, Tanimoto M
    • Organizer
      International Conference of the American Thoracic Society
    • Place of Presentation
      サンフランシスコ、米国
    • Year and Date
      2014-05-17 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26461189
  • [Presentation] Allergen-induced airway inflammation requires the receptor for advanced glycation end products triggering on airway structural cells

    • Author(s)
      A.Taniguchi, N.Miyahara, A.Kanehiro, K.Waseda, E.Kurimoto, U.Fujii, Y.Tanimoto, M.Kataoka, Y. Yamamoto, E.W. Gelfand , H. Yamamoto, M.Tanimoto.
    • Organizer
      Annual meeting of American Thoracic Society 2014
    • Place of Presentation
      Sandiego, CA, USA
    • Year and Date
      2014-05-17 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-24591463
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