Soh Junichi 宗淳一

… Alternative Names

SOH Junichi 宗淳一

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Researcher Number	90559890
Other IDs	https://orcid.org/0000-0001-8532-7915
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 近畿大学, 医学部, 教授 2019 – 2021: 近畿大学, 医学部, 准教授 2019: 近畿大学, 大学病院, 准教授 2013 – 2019: 岡山大学, 大学病院, 講師 2015: 岡山大学, 病院, 講師 … More 2012 – 2013: 岡山大学, 岡山大学病院, 助教 2011 – 2013: 岡山大学, 大学病院, 助教 2010: 岡山大学, 岡山大学病院, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 55040:Respiratory surgery-related / Respiratory surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Clinical oncology Except Principal Investigator Respiratory surgery / Basic Section 55040:Respiratory surgery-related / Thoracic surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator 薬剤耐性 / 肺がん / ERBB2 / HER2 / 腫瘍微小環境 / マイクロバイオーム / 早期肺腺がん / 標的薬 / 変異 / KRAS … More / HER異常 / 胃がん / 乳がん / HER2異常 / 肺癌 / サイトケラチン19 / マイクロRNA / 癌幹細胞 / 悪性胸膜中皮腫 / HSO90阻害剤 / FAK阻害剤 / 獲得耐性 / EGFR-TK1 / EGFR変異 / EGFR遺伝子変異 / EGFR-TKI阻害剤 … More Except Principal Investigator 肺癌 / EGFR / 非小細胞肺癌 / 外科 / 癌 / 悪性胸膜中皮腫 / マイクロRNA / 次世代シーケンサー / 次世代シークエンサー / 分子バーコード / 薬剤耐性 / 原発性肺癌 / 悪性中皮腫 / miR-34b/c / 胸部悪性腫瘍 / 肺線維化 / RAGE / ダメージ関連分子パターン / 腫瘍幹細胞マーカー / DCLK1 / 抗体療法 / 炎症 / 癌微小環境 / EGFR遺伝子変異 / LRIG1 / 上皮成長因子受容体チロシンキナーゼ阻害剤耐性 / Elacrida / ABCB1阻害剤 / EGFR-TKI耐性 / ゲノム / 生体生命情報学 / ターゲットシークエンス / がんゲノム医療 / compound mutation / VUS / co-mutation / ALK / 遺伝子変異解析 / 抗PD-1抗体 / メトホルミン / 分子標的治療薬 / PDX / EMT / 分子標的薬 / MHC Class1 / MHC Class-I / GRP78 / MHC Class I / NK細胞 / REIC / 遺伝子治療 / REIC遺伝子 / チロシンキナーゼ阻害剤 / 遺伝子変異 / HER2 / 上皮成長因子受容体チロシンキナーゼ阻害薬 / 上皮間葉移行 / 上皮成長因子受容体チロシンキナーゼ阻害剤 / 癌幹細胞 / 早期診断 / 血清DNA / デジタルPCR / DNAメチル化 / 胸膜悪性中皮腫 / 分子腫瘍学 Less

Basic Research for Elucidating and Overcoming the Mechanisms of Progression of Early-Stage Lung AdenocarcinomaPrincipal Investigator
- Principal Investigator
  
  宗淳一
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kindai University
Targeted therapy for the patient with KRAS mutant lung cancerPrincipal Investigator
- Principal Investigator
  
  宗淳一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kindai University
Development of a new treatment strategy for HER2-alterated lung cancerPrincipal Investigator
- Principal Investigator
  
  Soh Junichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kindai University
Novel treatment strategy for malignant pleural mesothelioma targeting the tumor stem cell marker DCLK1
- Principal Investigator
  
  Miyoshi Shinichiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Development of the novel therapy focused on damage-associated molecular patterns (DAMPs) for lung fibrosis-related diseases
- Principal Investigator
  
  Toyooka Shinichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Novel therapeutic strategy focused on EGFR-binding protein LRIG1 for EGFR-mutant lung cancer
- Principal Investigator
  
  Yamamoto Hiromasa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Okayama University
Development of innovative therapeutic antibodies targeting the inflammatory tumor microenvironment in refractory thoracic tumors
- Principal Investigator
  
  Toyooka Shinichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Okayama University
Gene mutation analysis using molecular-barcoding next-generation sequencer
- Principal Investigator
  
  Tomida Shuta
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Development of new therapeutic strategy based on gene expression and mutation profiles in EGFR mutant lung cancer
- Principal Investigator
  
  Toyooka Shinichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Novel therapeutic method for HER2 active cancer focusing on HER2 novel binding molecule cytokeratin 19Principal Investigator
- Principal Investigator
  
  SOH JUNICHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Development of new immunotherapy for lung cancer by combined application of diabetes drug metformin and anti-PD-1 antibody
- Principal Investigator
  
  Miyoshi Shinichiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Development of new therapeutic strategy for EGFR-TKI resistant non-small cell lung cancer.
- Principal Investigator
  
  Asano Hiroaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Identification of novel targets in the treatment of lung cancer
- Principal Investigator
  
  Miyoshi Shinichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
New therapeutic strategy for non-small cell lung cancer by REIC gene therapy
- Principal Investigator
  
  Toyooka Shinichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Understanding and overcoming drug resistance to EGFR-inhibitors for lung cancer
- Principal Investigator
  
  Toyooka Shinichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
New treatment strategy for malignant pleural mesothelioma focusing on microRNAs related to cancer stem cell makersPrincipal Investigator
- Principal Investigator
  
  SOH JUNICHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Okayama University
Detection of aberrant expression of microRNAs and development of new diagnostics and treatment in lung cancer
- Principal Investigator
  
  MIYOSHI Shinichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
Establishment of the high sensitive assay for detecting malignant pleural mesothelioma-specific DNA methylation
- Principal Investigator
  
  ASANO HIROAKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
Development of the new therapeutic approach for malignant pleural mesothelioma by the elucidation of aberrant microRNA expression
- Principal Investigator
  
  TOYOOKA Shinichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Okayama University
A study for the effect of EGFR-tyrosine kinase inhibitor in lung cancer with activating EGFR mutationPrincipal Investigator
- Principal Investigator
  
  SOH Junichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Okayama University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Activity and mechanism of acquired resistance to tarloxotinib in HER2 mutant lung cancer: an in vitro study.2021
- Author(s)
  Koga T, Suda K, Nishino M, Fujino T, Ohara S, Hamada A, Soh J, Tirunagaru V, Vellanki A, Doebele RC, Mitsudomi T.
- Journal Title
  
  Translational Lung Cancer Research
  
  Volume: 10 Issue: 8 Pages: 3659-3670
- DOI
  10.21037/tlcr-21-216
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07336, KAKENHI-PROJECT-19K09285
[Journal Article] In vitro validation study of HER2 and HER4 mutations identified in an ad hoc secondary analysis of the LUX-Lung 8 randomized clinical trial.2021
- Author(s)
  Hamada A, Suda K, Koga T, Fujino T, Nishino M, Ohara S, Chiba M, Shimoji M, Takemoto T, Soh J, Uchida T, Mitsudomi T.
- Journal Title
  
  Lung Cancer
  
  Volume: 162 Pages: 79-85
- DOI
  10.1016/j.lungcan.2021.10.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07336, KAKENHI-PROJECT-19K09285, KAKENHI-PROJECT-20K17763
[Journal Article] YES1 activation induces acquired resistance to neratinib in HER2 ‐amplified breast and lung cancers2020
- Author(s)
  Takeda Tatsuaki、Yamamoto Hiromasa、Suzawa Ken、Tomida Shuta、Miyauchi Shunsaku、Araki Kota、Nakata Kentaro、Miura Akihiro、Namba Kei、Shien Kazuhiko、Soh Junichi、Shien Tadahiko、Kitamura Yoshihisa、Sendo Toshiaki、Toyooka Shinichi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 3 Pages: 849-856
- DOI
  10.1111/cas.14289
- NAID
  120006839439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09070, KAKENHI-PROJECT-19K09285, KAKENHI-PROJECT-17K10784
[Journal Article] Acquired resistance mechanisms to afatinib in HER2-amplified gastric cancer cells2019
- Author(s)
  Yoshioka, T. Shien, K. Takeda, T. Takahashi, Y. Kurihara, E. Ogoshi, Y. Namba, K. Torigoe, H. Sato, H. Tomida, S. Yamamoto, H. Soh, J. Fujiwara, T. Toyooka, S.
- Journal Title
  
  Cancer Sci
  
  Volume: 110 Issue: 8 Pages: 2549-2557
- DOI
  10.1111/cas.14089
- NAID
  120006816640
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09285, KAKENHI-PROJECT-17K10784
[Journal Article] Application of amplicon-based targeted sequencing with the molecular barcoding system to detect uncommon minor EGFR mutations in patients with treatment-naive lung adenocarcinoma2019
- Author(s)
  Namba Kei、Tomida Shuta、Matsubara Takehiro、Takahashi Yuta、Kurihara Eisuke、Ogoshi Yusuke、Yoshioka Takahiro、Takeda Tatsuaki、Torigoe Hidejiro、Sato Hiroki、Shien Kazuhiko、Yamamoto Hiromasa、Soh Junichi、Tsukuda Kazunori、Toyooka Shinichi
- Journal Title
  
  BMC Cancer
  
  Volume: 19 Issue: 1 Pages: 1-9
- DOI
  10.1186/s12885-019-5374-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10784, KAKENHI-PROJECT-16H05431
[Journal Article] Anti-tumor effect of neratinib against lung cancer cells harboring HER2 oncogene alterations.2019
- Author(s)
  Ogoshi Y, Shien K, Yoshioka T, Torigoe H, Sato H, Sakaguchi M, Tomida S, Namba K, Kurihara E, Takahashi Y, Suzawa K, Yamamoto H, Soh J, Toyooka S
- Journal Title
  
  Oncol Lett.
  
  Volume: - Pages: 2729-2736
- DOI
  10.3892/ol.2019.9908
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K10681
[Journal Article] Activation of AXL as a Preclinical Acquired Resistance Mechanism Against Osimertinib Treatment in EGFR-Mutant Non-Small Cell Lung Cancer Cells2019
- Author(s)
  Namba Kei、Shien Kazuhiko、Takahashi Yuta、Torigoe Hidejiro、Sato Hiroki、Yoshioka Takahiro、Takeda Tatsuaki、Kurihara Eisuke、Ogoshi Yusuke、Yamamoto Hiromasa、Soh Junichi、Tomida Shuta、Toyooka Shinichi
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 17 Issue: 2 Pages: 499-507
- DOI
  10.1158/1541-7786.mcr-18-0628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10784, KAKENHI-PROJECT-16H05431, KAKENHI-PROJECT-17K16608
[Journal Article] Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma2018
- Author(s)
  Sato Hiroki、Sakaguchi Masakiyo、Yamamoto Hiromasa、Tomida Shuta、Aoe Keisuke、Shien Kazuhiko、Yoshioka Takahiro、Namba Kei、Torigoe Hidejiro、Soh Junichi、Tsukuda Kazunori、Tao Hiroyuki、Okabe Kazunori、Miyoshi Shinichiro、Pass Harvey I.、Toyooka Shinichi
- Journal Title
  
  Oncogenesis
  
  Volume: 7 Issue: 1 Pages: 11-11
- DOI
  10.1038/s41389-017-0017-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10784, KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-17H03577
[Journal Article] Antitumor activity of pan-HER inhibitors in HER2-positive gastric cancer.2018
- Author(s)
  Yoshioka T, Shien K, Namba K, Torigoe H, Sato H, Tomida S, Yamamoto H, Asano H, Soh J, Tsukuda K, Nagasaka T, Fujiwara T, Toyooka S.
- Journal Title
  
  Cancer Sci.
  
  Volume: 109 Issue: 4 Pages: 1166-1176
- DOI
  10.1111/cas.13546
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10681, KAKENHI-PROJECT-18K18464, KAKENHI-PROJECT-18H03554, KAKENHI-PROJECT-15H03034
[Journal Article] Comparative mutational evaluation of multiple lung cancers by multiplex oncogene mutation analysis2018
- Author(s)
  Takahashi Yuta、Shien Kazuhiko、Tomida Shuta、Oda Shinsuke、Matsubara Takehiro、Sato Hiroki、Suzawa Ken、Kurihara Eisuke、Ogoshi Yusuke、Namba Kei、Yoshioka Takahiro、Torigoe Hidejiro、Yamamoto Hiromasa、Soh Junichi、Toyooka Shinichi
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 11 Pages: 3634-3642
- DOI
  10.1111/cas.13797
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10784
[Journal Article] Tumor-suppressive effect of LRIG1, a negative regulator of ErbB, in non-small cell lung cancer harboring mutant EGFR2018
- Author(s)
  Torigoe H, Yamamoto H, Sakaguchi M, Youyi C, Numba K, Sato H, Shien K, Soh J, Suzawa K, Tomida S, Tsukuda K, Miyoshi S, Toyooka S
- Journal Title
  
  Carcinogenesis
  
  Volume: - Issue: 5 Pages: 719-727
- DOI
  10.1093/carcin/bgy044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-18K08783
[Journal Article] Elacridar, a third-generation ABCB1 inhibitor, overcomes resistance to docetaxel in non-small cell lung cancer.2017
- Author(s)
  Chen H, Shien K, Suzawa K, Tsukuda K, Tomida S, Sato H, Torigoe H, Watanabe M, Namba K, Yamamoto H, Soh J, Asano H, Miyoshi S, Toyooka S
- Journal Title
  
  Oncology Letters
  
  Volume: 14(4) Issue: 4 Pages: 4349-4354
- DOI
  10.3892/ol.2017.6678
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10258
[Journal Article] Distant Bystander Effect of REIC/DKK3 Gene Therapy Through Immune System Stimulation in Thoracic Malignancies.2017
- Author(s)
  Suzawa K, Shien K, Peng H, Sakaguchi M, Watanabe M, Hashida S, Maki Y, Yamamoto H, Tomida S, Soh J, Asano H, Tsukuda K, Nasu Y, Kumon H, Miyoshi S, Toyooka S.
- Journal Title
  
  Anticancer Research
  
  Volume: 37 Pages: 301-307
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670627
[Journal Article] Establishment and molecular characterization of cell lines from Japanese patients with malignant pleural mesothelioma.2016
- Author(s)
  Suzawa K, Yamamoto H, Murakami T, Katayama H, Furukawa M, Shien K, Hashida S, Okabe K, Aoe K, Soh J, Asano H, Tsukuda K, Mimura Y, Toyooka S, Miyoshi S
- Journal Title
  
  Oncol Lett
  
  Volume: 1 Issue: 1 Pages: 705-712
- DOI
  10.3892/ol.2015.3955
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462195
[Journal Article] Interaction of cytokeratin 19 head domain and HER2 in the cytoplasm leads to activation of HER2-Erk pathway.2016
- Author(s)
  Ohtsuka T, Sakaguchi M, Yamamoto H, Tomida S, Takata K, Shien K, Hashida S, Miyata-Takata T, Watanabe M, Suzawa K, Soh J, Youyi C, Sato H, Namba K, Torigoe H, Tsukuda K, Yoshino T, Miyoshi S, Toyooka S.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 39557-39557
- DOI
  10.1038/srep39557
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-26293318, KAKENHI-PROJECT-26293352, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-16K10681
[Journal Article] Antitumor effect of afatinib, as a human epidermal growth factor receptor 2-targeted therapy, in lung cancers harboring HER2 oncogene alterations2016
- Author(s)
  Ken Suzawa, Shinichi Toyooka, Masakiyo Sakaguchi, Mizuki Morita, Hiromasa Yamamoto, Shuta Tomida, Tomoaki Ohtsuka, Mototsugu Watanabe, Shinsuke Hashida, Yuho Maki, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda and Shinichiro Miyoshi
- Journal Title
  
  Cancer Science
  
  Volume: 107 Issue: 1 Pages: 45-52
- DOI
  10.1111/cas.12845
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293318, KAKENHI-PROJECT-26293352
[Journal Article] TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells2015
- Author(s)
  Otani H, Yamamoto H, Takaoka M, Sakaguchi M, Soh J, Jida M, Ueno T, Kubo T, Asano H, Tsukuda K, Kiura K, Hatakeyama S, Kawahara E, Naomoto Y, Miyoshi S, Toyooka S
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0129838-e0129838
- DOI
  10.1371/journal.pone.0129838
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-25293302, KAKENHI-PROJECT-26290039
[Journal Article] Hsp90 inhibitor NVP-AUY922 enhances the radiation sensitivity of lung cancer cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors.2015
- Author(s)
  Hashida S, Yamamoto H, Shien K, Ohtsuka T, Suzawa K, Maki Y, Furukawa M, Soh J, Asano H, Tsukuda K, Miyoshi S, Kanazawa S, Toyooka S
- Journal Title
  
  Oncology Reports
  
  Volume: 33 Issue: 3 Pages: 1499-1504
- DOI
  10.3892/or.2015.3735
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791462, KAKENHI-PROJECT-25293302
[Journal Article] Acquisition of cancer stem cell-like properties in non-small cell lung cancer with acquired resistance to afatinib2015
- Author(s)
  Shinsuke Hashida, Hiromasa Yamamoto, Kazuhiko Shien, Yuichiro Miyoshi, Tomoaki Ohtsuka, Ken Suzawa, Mototsugu Watanabe, Yuho Maki, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Journal Title
  
  Cancer Science
  
  Volume: 10 Issue: 10 Pages: 1377-1384
- DOI
  10.1111/cas.12749
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293302
[Journal Article] Preclinical evaluation of microRNA-34b/c delivery for malignant pleural mesothelioma.2014
- Author(s)
  Ueno T, Toyooka S, Fukazawa T, Kubo T, Soh J, Asano H, Muraoka T, Tanaka N, Maki Y, Shien K, Furukawa M, Sakaguchi M, Yamamoto H, Tsukuda K, Miyoshi S.
- Journal Title
  
  Acta Med Okayama
  
  Volume: 68 Pages: 23-26
- NAID
  120005372648
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592061
[Journal Article] Anti-Cancer Effects of REIC/Dkk-3-encoding Adenoviral Vector for the Treatment of Non-small Cell Lung Cancer2014
- Author(s)
  Shien K, Tanaka N, Watanabe M, Soh J, Sakaguchi M, Matsuo K, Yamamoto H, Furukawa M, Asano H, Tsukuda K, Nasu Y, Huh NH, Miyoshi S, Kumon H, Toyooka S
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 2 Pages: e87900-e87900
- DOI
  10.1371/journal.pone.0087900
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-26670627
[Journal Article] Preclinical evaluation of microRNA-34b/c deliverly for malignant pleural mesothelioma2014
- Author(s)
  Ueno T, Toyooka S, Fukazawa T, Kubo T, Soh J, Asano H, Muraoka T, Tanaka N, Maki Y, Shien K, Furukawa M, Sakaguchi M, Yamamoto H, Tsukuda K, Miyoshi S
- Journal Title
  
  Acta Med Okayama
  
  Volume: 68(1) Pages: 23-26
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24553485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592061
[Journal Article] The degree of microRNA-34b/c methylation in serum-circulating DNA is associated with malignant pleural mesothelioma.2013
- Author(s)
  Muraoka T, Soh J, Toyooka S, Aoe K, Fujimoto N, Hashida S, Maki Y, Tanaka N, Shien K, Furukawa M, Yamamoto H, Asano H, Tsukuda K, Kishimoto T, Otsuki T, Miyoshi S.
- Journal Title
  
  Lung Cancer
  
  Volume: 82 Issue: 3 Pages: 485-490
- DOI
  10.1016/j.lungcan.2013.09.017
- NAID
  120005367626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592061, KAKENHI-PROJECT-23791570
[Journal Article] Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells2013
- Author(s)
  Shien K, Toyooka S, Yamamoto H, Soh J, Jida M, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S
- Journal Title
  
  Cancer Res
  
  Volume: 73(10) Pages: 3051-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592061
[Journal Article] Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells.2013
- Author(s)
  Shien K, Toyooka S, Yamamoto H, Soh J, Jida M, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S.
- Journal Title
  
  Cancer Res.
  
  Volume: 73 Issue: 10 Pages: 3051-3061
- DOI
  10.1158/0008-5472.can-12-4136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-23592061
[Journal Article] Downregulation of microRNA-34 induces cell proliferation and invasion of human mesothelial cells2013
- Author(s)
  Tanaka N, Toyooka S, Soh J, Tsukuda K, Shien K, Furukawa M, Muraoka T, Maki Y, Ueno T, Yamamoto H, Asano H, Otsuki T, Miyoshi S
- Journal Title
  
  Oncol Rep
  
  Volume: 29(6) Issue: 6 Pages: 2169-74
- DOI
  10.3892/or.2013.2351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591566, KAKENHI-PROJECT-23592061
[Journal Article] Frequent methylation and oncogenic role of microRNA-34b/c in small-cell lung cancer2012
- Author(s)
  Tanaka N, Toyooka S, Soh J, Kubo T, Yamamoto H, Maki Y, Muraoka T, Shien K, Furukawa M, Ueno T, Asano H, Tsukuda K, Aoe K, Miyoshi S
- Journal Title
  
  Lung Cancer
  
  Volume: 76(1) Issue: 1 Pages: 32-8
- DOI
  10.1016/j.lungcan.2011.10.002
- NAID
  120005311982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592061
[Journal Article] MicroRNA miR-34b/c enhances cellular radiosensitivity of malignant pleural mesothelioma cells2012
- Author(s)
  Maki Y, Asano H, Toyooka S, Soh J, Kubo T, Katsui K, Ueno T, Shien K, Muraoka T, Tanaka N, Yamamoto H, Tsukuda K, Kishimoto T, Kanazawa S, Miyoshi S
- Journal Title
  
  Anticancer Res
  
  Volume: 32(11) Pages: 4871-5
- URL
  http://ar.iiarjournals.org/content/32/11/4871.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591566
[Journal Article] EGFRチロシンキナーゼ阻害剤に対する耐性機構と克服2012
- Author(s)
  宗淳一, 豊岡伸一, 上野剛, 三好新一郎
- Journal Title
  
  肺癌
  
  Volume: 52巻 Pages: 131-135
- NAID
  130002060224
- Data Source
  KAKENHI-PROJECT-22700916
[Journal Article] EGFR チロシンキナーゼ阻害剤に対する耐性機構と克服2012
- Author(s)
  宗　淳一
- Journal Title
  
  肺癌
  
  Volume: 52 Pages: 131-135
- NAID
  130002060224
- Data Source
  KAKENHI-PROJECT-22700916
[Journal Article] Epigenetic silencing of microRNA-34b/c plays an important role in the pathogenesis of malignant pleural mesothelioma2011
- Author(s)
  Kubo T, Toyooka S, Tsukuda K, Sakaguchi M, Fukazawa T, Soh J, Asano H, Ueno T, Muraoka T, Yamamoto H, Nasu Y, Kishimoto T, Pass HI, Matsui H, Huh NH, Miyoshi S
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17(15) Issue: 15 Pages: 4965-74
- DOI
  10.1158/1078-0432.ccr-10-3040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591566
[Journal Article]2010
- Author(s)
  豊岡伸一, 光冨徹哉, 宗淳一, 山本寛斉, 三好新一郎
- Journal Title
  
  肺癌
  
  Volume: 50巻 Pages: 329-341
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] In Vitro Validation Study for HER2 Mutations in Squamous Cell Carcinoma as a Potential Predictive Factor Identified in Secondary Analysis of the LUX-Lung 8 Trial2020
- Author(s)
  Akira Hamada, Kenichi Suda, Toshio Fujino, Masaya Nishino, Takamasa Koga, Shuta Ohara, Masato Chiba, Toshiki Takemoto, Junichi Soh, Tetsuya Mitsudomi
- Organizer
  2020 World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09285
[Presentation] In Vitro Validation Study for Afatinib Efficacy in Lung Squamous Cell Carcinoma with HER2 Mutations Identified in LUX-Lung 8 Trial2020
- Author(s)
  Akira Hamada, Kenichi Suda, Toshio Fujino Shuta Ohara, Junichi Soh, Tetsuya Mitsudomi
- Organizer
  第79回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-19K09285
[Presentation] Clinicopathological characteristics of lung cancer patients with concomitant idiopathic pulmonary fibrosis2019
- Author(s)
  Kota Araki, Kazuhiko Shien, Shunsaku Miyauchi, Akihiro Miura, Yuta Takahashi, Eisuke Kurihara, Yusuke Ogoshi, Kei Namba, Ken Suzawa, Hiromasa Yamamoto, Shuta Tomida, Junichi Soh, Masakiyo Sakaguchi, Shinichi Toyooka
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19581
[Presentation] Doublecortin-like Kinase 1 (DCLK1) correlates with the cell proliferation in malignant pleural mesothelioma2019
- Author(s)
  Akihiro Miura, Hiromasa Yamamoto, Hiroyuki Tao, Ken Suzawa, Shunsaku Miyauchi, Kota Araki, Yuta Takahashi, Eisuke Kurihara, Yusuke Ogoshi, Kazuhiko Shien, Junichi Soh, Kazunori Okabe, Shuta Tomida, Masakiyo Sakaguchi, Shinichi Toyooka
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09286
[Presentation] Activation of AXL as a preclinical acquired resistance mechanism against osimertinib treatment in EGFR-mutant non-small cell lung cancer cells2019
- Author(s)
  Kei Namba, Kazuhiko Shien, Yuta Takahashi, Hiroki Sato, Takahiro Yoshioka, Ken Suzawa, Hiromasa Yamamoto, Junichi Soh, Shuta Tomida, Shinichi Toyooka
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05431
[Presentation] Antitumor effect of neratinib in lung cancers harboring HER2 oncogene alterations2018
- Author(s)
  Yusuke Ogoshi, shinichi Toyooka, Jyunichi Soh, hiromasa Yamamoto, Kazuhiko Shien, Hidejiro torigoe, Hiroki sato, Takahiro Yoshioka, Kei Namba, Yuta Takahashi, and Eisuke Kurihara
- Organizer
  AACR2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10681
[Presentation] EGFR 変異陽性肺癌における LRIG1 の抗腫瘍効果2018
- Author(s)
  鳥越英次郎、山本寛斉、阪口政清、難波圭、佐藤博紀、枝園和彦、諏澤憲、宗淳一、冨田秀太、佃和憲、三好新一郎、豊岡伸一
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08783
[Presentation] 分子バーコード技術を用いた低頻度多重変異の同定2017
- Author(s)
  難波圭、冨田秀太、枝園和彦、山本寛斉、宗淳一、佃和憲、豊岡伸一
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10784
[Presentation] Metformin improves immune function of exhausted peripheral CD8+ T cells derived from cancer patients2017
- Author(s)
  Mototsugu Watanabe, Shingo Eikawa, Kazuhiko Shien, Hiromasa Yamamoto, Tadahiko Shien, Junichi Soh, Hiroyoshi Doihara, Shinichi Toyooka, Shinichiro Miyoshi, Heiichiro Udono
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15637
[Presentation] Multiple acquired resistance mechanisms against third generation EGFR-TKI osimertinib in non-small cell lung cancer cells2017
- Author(s)
  Kei Namba, Kazuhiko Shien, Hidejiro Torigoe, Hiroki Sato, Hiromasa Yamamoto, Junichi Soh, Kazunori Tsukuda, Shinichi Toyooka
- Organizer
  第58回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05431
[Presentation] Detection of multiple low-frequency mutations by molecular-barcode sequencing2017
- Author(s)
  Kei Namba, Shuta Tomida, Hidejiro Torigoe, Hiroki Sato, Kazuhiko Shien, Hiromasa Yamamoto, Junichi Soh, Kazunori Tsukuda, Shinichi Toyooka
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H05431
[Presentation] Cytokeratin 19 binds to HER2 and activates HER2 and its downstream signaling2016
- Author(s)
  Tomoaki Ohtsuka, Masakiyo Sakaguchi, Shuta Tomida, Hiromasa Yamamoto, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Junichi Soh, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Maui, Hawaii, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] Detection of multiple low-frequency mutations by molecular-barcode sequencing2016
- Author(s)
  Kei Namba, Shuta Tomida, Ken Suzawa, Hidejiro Torigoe, Hiroki Sato, Hiromasa Yamamoto, Junichi Soh, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  IASLC 17TH WORLD CONFERENCE ON LUNG CANCER
- Place of Presentation
  Vienna, Austria
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05431
[Presentation] Detection of multiple low-frequency mutations by molecular-barcode sequencing2016
- Author(s)
  Kei Namba, Shuta Tomida, Kazuhiko Shien, Hidejiro Torigoe, Hiroki Sato, Hiromasa Yamamoto, Junichi Soh, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  第57回日本肺癌学会総会
- Place of Presentation
  福岡市
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-16H05431
[Presentation] Ｔhe proof of concept of REIC/Dkk-3 gene therapy for thoracic malignancies.2016
- Author(s)
  Shinichi Toyooka, Ken Suzawa, Kazuhiko Shien, Masakiyo Sakaguchi, Masami Watanabe, Peng Huang, Kei Namba, Hidejiro Torigoe, Hiroki Sato, Junichi Soh, Hiromasa Yamamoto, Yuho Maki, Kazunori Tsukuda, Shuta Tomida, Yasutomo Nasu, Hiromi Kumon, Shinichiro Miyoshi
- Organizer
  １０ｔｈ AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  米国
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670627
[Presentation] 胸部悪性腫瘍に対するREIC遺伝子治療2016
- Author(s)
  豊岡伸一、諏澤憲、枝園和彦、牧佑歩、山本寛斉、宗淳一、山根正修、大藤剛宏、公文裕巳、三好新一郎
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-26670627
[Presentation] 悪性胸膜中皮腫に対するREIC/Dkk-3遺伝子治療2016
- Author(s)
  山本寛斉、諏澤憲、枝園和彦、宗淳一、三好健太郎、大谷真二、杉本誠一郎、山根正修、大藤剛宏、三好新一郎、豊岡伸一
- Organizer
  第69回日本胸部外科学会定期学術集会
- Place of Presentation
  岡山
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-26670627
[Presentation] Distant bystander effect of REIC/Dkk-3 gene therapy through immune system stimulation in a murine model of thoracic malignancies2015
- Author(s)
  Ken Suzawa, Kazuhiko Shien, Pen Huang, Masakiyo Sakaguchi, Mototsugu Watanabe, Shinsuke Hashida, Junichi Soh, Hiromasa Yamamoto, Yuho Maki, Hiroaki Asano, Kazunori Tsukuda, Yasutomo Nasu, Hiromi Kumon, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  16th World Conference on Lung Cancer
- Place of Presentation
  名古屋
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670627
[Presentation] Adenovirus-mediated REIC/Dkk-3 gene therapy shows indirect antitumor effects on thoracic malignancies through immune system stimulation2015
- Author(s)
  Ken Suzawa, Kazuhiko Shien, Masakiyo Sakaguchi, Masami Watanabe, Shinsuke Hashida, Junichi Soh, Hiromasa Yamamoto, Yuho Maki, Kazunori Tsukuda, Yasutomo Nasu, Hiromi Kumon, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  米国
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670627
[Presentation] Anti-tumor effect of afatinib, an irreversible EGFR/HER2 dual inhibitor, in lung cancers harboring HER2 oncogene2015
- Author(s)
  Ken Suzawa, Shinichi Toyooka, Masakiyo Sakaguchi, Tomoaki Ohtsuka, Mototsugu Watanabe, Shinsuke Hashida, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] TAE226, a bis-anilino pyrimidine compound, shows anti-tumor effect on EGFR-mutant non-small cell lung cancer cells including T790M mutant2015
- Author(s)
  Hiromasa Yamamoto, Hiroki Otani, Munenori Takaoka, Masakiyo Sakaguchi, Junichi Soh, Masaru Jida, Tsuyoshi Ueno, Takafumi Kubo, Hiroaki Asano, Kazunori Tsukuda, Katsuyuki Kiura, Shinji Hatakeyama, Eiji Kawahara, Yoshio Naomoto, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  16th World Conference on Lung Cancer
- Place of Presentation
  米国
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293302
[Presentation] HER2関連肺癌に対するアファチニブの抗腫瘍効果2015
- Author(s)
  諏澤　　憲，豊岡　伸一，大塚　智昭，渡邉　元嗣，橋田　真輔，牧　　佑歩，山本　寛斉，宗　　淳一，岡田　真典，伊賀　徳周，三好健太郎，杉本誠一郎，山根　正修，大藤　剛宏，三好新一郎
- Organizer
  第58回関西胸部外科学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] Docetaxel-resitant non-small cell lung cancer cells that acquired cross-resistance to EGFR-tyrosine kinase inhibitor2015
- Author(s)
  Haiyang Chen, Ken Suzawa, Shinsuke Hashida, Tomoaki Ohtsuka, Mototsugu Watanabe, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293302
[Presentation] Identification of a novel binding protein playing a critical role in HER2 activation in lung cancer cells2015
- Author(s)
  Tomoaki Ohtsuka, Masakiyo Sakaguchi, Katsuyoshi Takata, Shinsuke Hashida, Mototsugu Watanabe, Ken Suzawa, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] Effect of Hsp90 inhibitor NVP-AUY922 with radiation on lung adenocarcinoma cell lines with acquired resistance to EGFR-tyrosine kinase inhibitors2015
- Author(s)
  Yuho Maki, Shinsuke Hashida, Hiromasa Yamamoto, Kazuhiko Shien, Tomoaki Ohtsuka, Ken Suzawa, Masashi Furukawa, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi, Susumu Kanazawa, Shinichi Toyooka
- Organizer
  AACR 106th Annual Meeting
- Place of Presentation
  米国
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293302
[Presentation] 悪性胸膜中皮腫に対するREIC/Dkk-3遺伝子治療2015
- Author(s)
  山本寛斉、枝園和彦、牧佑歩、宗淳一、大谷真二、三好健太郎、杉本誠一郎、山根正修、大藤剛宏、渡部昌実、那須保友、公文裕巳、三好新一郎、豊岡伸一
- Organizer
  第56回日本肺癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-26670627
[Presentation] 悪性胸膜中皮腫に対するREIC/Dkk-3遺伝子治療2015
- Author(s)
  山本寛斉、枝園和彦、牧佑歩、宗淳一、大谷真二、三好健太郎、杉本誠一郎、山根正修、大藤剛宏、渡部昌実、那須保友、公文裕巳、三好新一郎、豊岡伸一
- Organizer
  第56回日本肺癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25462195
[Presentation] Anti-tumor effect of a bis-anilino pyrimidine compound TAE226 on EGFR-mutant non-small cell lung cancer cells with or without T790M mutation2015
- Author(s)
  Hiromasa Yamamoto, Hiroki Otani, Munenori Takaoka, Masakiyo Sakaguchi, Junichi Soh, Masaru Jida, Tsuyoshi Ueno, Takafumi Kubo, Hiroaki Asano, Kazunori Tsukuda, Katsuyuki Kiura, Shinji Hatakeyama, Eiji Kawahara, Yoshio Naomoto, Shinichiro Miyoshi, Shinichi Toyooka
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25293302
[Presentation] The molecular characters of acquired resistant non-small cell lung cancer cells to afatinib2014
- Author(s)
  Shinsuke Hashida, Shinichi Toyooka, Tomoaki Ohtsuka, Ken Suzawa, Kazuhiko Shien, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda,Shinichiro Miyoshi
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego, California, U.S.A
- Data Source
  KAKENHI-PROJECT-25293302
[Presentation] Acquisition of stem cell-like properties during acquired resistance to epidermal growth factor receptor inhibitors2013
- Author(s)
  Shien K, Toyooka S, Yamamoto H, Soh J, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington DC, USA
- Year and Date
  2013-04-09
- Data Source
  KAKENHI-PROJECT-23592061
[Presentation] Knockdown of EGFR to investigate its therapeutic potential for treatment of non-small cell lung cancers2012
- Author(s)
  Junichi Soh
- Organizer
  AACR annual meeting 2012
- Place of Presentation
  Chicag, IL, USA
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] Down-regulation of microRNA34 induces cell proliferation and invasion of human mesothelial cells2012
- Author(s)
  Tanaka N, Toyooka S, Soh J, Tsukuda K, Shien K, Furukawa M, Muraoka T, Maki Y, Ueno T, Asano H, Otsuki T, Miyoshi S
- Organizer
  AACR Annual Meeting 2012
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-22591566
[Presentation] Down-regulation of microRNA-34 induces cell proliferation and invasion of human mesothelial cells2012
- Author(s)
  Tanaka N, Toyooka S, Soh J, Tsukuda K, Shien K, Furukawa M, Muraoka T, Maki Y, Ueno T, Asano H, Otsuki T, Miyoshi S
- Organizer
  103rd AACR Annual Meeting
- Place of Presentation
  Chicago, USA
- Year and Date
  2012-04-01
- Data Source
  KAKENHI-PROJECT-23592061
[Presentation] Knockdown of EGFR to investigate its therapeutic potential for treatment of non-small cell lung cancers2012
- Author(s)
  J Soh, K Shien, T Ueno, K Tsukuda, K Suda, T Kubo, M Furukawa, T Muraoka, Y Maki, N Tanaka, H Yamamoto, K Kiura, T Mitsudomi, S Toyooka, S Miyoshi
- Organizer
  AACR2012
- Place of Presentation
  シカゴ、アメリカ
- Year and Date
  2012-04-01
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] 肺がんの亜分類と標的治療分子標的薬の今後の展望(Beyond EGFR/ALK/HER2)2011
- Author(s)
  豊岡伸一, 宗淳一, 上野剛, 山根正修, 大藤剛宏, 三好新一郎
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] The impact of adenoviral gene transfer of microRNA-34b/c on malignant pleural mesotheliomas2011
- Author(s)
  宗淳一
- Organizer
  第102回米国癌学会
- Place of Presentation
  米国
- Year and Date
  2011-04-06
- Data Source
  KAKENHI-PROJECT-22591566
[Presentation] The impact of adenoviral gene transfer of microRNA-34b/c on malignant pleural mesotheliomas.2011
- Author(s)
  Soh J, Toyooka S, Kubo T, Fukazawa T, Sakaguchi M, Ueno T, Tsukuda K, Asano H, Yamamoto H, Huh, N, Miyoshi S
- Organizer
  AACR Annual Meeting 2011
- Place of Presentation
  Orlando, USA
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-22591566
[Presentation] 小細胞肺癌におけるmicroRNA-34b/cのメチル化とその役割2011
- Author(s)
  田中則光、豊岡伸一、宗淳一、浅野博昭、佃和憲、三好新一郎
- Organizer
  日本癌治療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23592061
[Presentation] MicroRNA-34b/c is significantly down-regulated by aberrant promoter methylation and forced expression of miR-34b/c enhances the radiosensitivity in malignant pleural mesothelioma cells.2011
- Author(s)
  Maki Y, Toyooka S, Asano H, Soh J, Tsukuda K, Muraoka T, Aokage K, Tanaka N, Ueno T, Yamane M, Oto T, Miyoshi S
- Organizer
  AACR Annual Meeting 2011
- Place of Presentation
  Orlando, USA
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-22591566
[Presentation] 小細胞肺癌におけるmicroRNA-34b/cのメチル化とその役割2011
- Author(s)
  田中則光、豊岡伸一、宗淳一、浅野博昭、佃和憲、三好新一郎
- Organizer
  日本癌治療学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23592061
[Presentation] EGFRチロシンキナーゼ阻害剤に対する耐性株の樹立と分子生物学的特徴の検討2010
- Author(s)
  上野剛, 豊岡伸一, 宗淳一, 治田賢, 久保孝文, 浅野博昭, 佃和憲, 山根正修, 大藤剛宏, 三好新一郎
- Organizer
  第27回日本呼吸器外科学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] The anti-tumor effect of TAE226, dual inhibitor of FAK and IGF-IR, on non-small-cell lung cancer with EGFR mutation2010
- Author(s)
  H Otani, S Toyooka, M Takaoka, M Sakaguchi, T Ueno, H Yamamoto, J Soh, T Kubo, H Asano, K Tsukuda, M Yamane, T Oto, K Kiura, N Huh, Y Naomoto, S Miyoshi
- Organizer
  AACR2010
- Place of Presentation
  ワシントンDC、アメリカ
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] 正常中皮細胞におけるmicroRNA34の抑制効果 Tiny RNA drives mesothelial cell mad2010
- Author(s)
  田中則光、豊岡伸一、宗淳一、牧佑歩、村岡孝幸、上野剛、浅野博昭、佃和憲、三好新一郎
- Organizer
  日本癌治療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591566
[Presentation] 肺癌細胞株におけるTAE226の変異型EGFRチロシンキナーゼ特異的な不活化作用とその抗腫瘍効果の検討2010
- Author(s)
  宗淳一
- Organizer
  第83回日本組織培養学会総会
- Place of Presentation
  岡山
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] Epigenetic silencing of microRNA-34b/c plays a pivotal role in the pathogenesis of malignant pleural mesothelioma2010
- Author(s)
  Toyooka S, Kubo T, Tsukuda K, Sakaguchi M, Fukazawa T, Soh J, Asano H, Nasu Y, Kishimoto T, Pass H, Matsui H, Huh NH, Miyoshi S
- Organizer
  The 10th International Conference of the International Mesothelioma Interest Group
- Place of Presentation
  京都
- Year and Date
  2010-09-01
- Data Source
  KAKENHI-PROJECT-22591566
[Presentation] 、肺癌細胞株におけるTAE226 の変異型EGFRチロシンキナーゼ特異的な不活化作用とその抗腫瘍効果の検討2010
- Author(s)
  宗淳一, 豊岡伸一, 大谷弘樹, 高岡宗徳, 阪口正清, 治田賢, 久保孝文, 山本寛斉, 浅野博昭, 佃和憲, 木浦勝行, 許南浩, 猶本良夫, 三好新一郎
- Organizer
  第83回日本組織培養学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] Epigenetic silencing of micro-RNA-34b/c plays a pivotal role in pathogenesis of malignant mesothelioma2010
- Author(s)
  久保孝文、豊岡伸一、佃和憲、阪口政清、深澤拓也、宗淳一、浅野博昭、上野剛、那須康友、松井秀樹、許南浩、三好新一郎
- Organizer
  第69回日本肺癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22591566
[Presentation] Frequent silencing of tumor suppressive miR-34b/c by aberrant methylation in malignant pleural mesothelioma2010
- Author(s)
  Kubo T, Toyooka S, Tsukuda K, Asano H, Sakaguchi M, Soh J, Ueno T, Yamamoto H, Yamane M, Oto T, Nasu Y, Matsui H, Huh NH, Miyoshi S
- Organizer
  AACR Annual Meeting 2010
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-22591566
[Presentation] 肺癌の分子標的治療基礎から臨床へ EGFR-TKIの耐性機構とその克服2010
- Author(s)
  豊岡伸一, 宗淳一, 大谷弘樹, 小林成行, 久保孝文, 上野剛, 青景圭樹, 山根正修, 大藤剛宏, 木浦勝行, 三好新一郎
- Organizer
  第51回日本肺癌学会総会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22700916
[Presentation] The molecular characters of acquired resistant non－small cell lung cancer cells to afatinib
- Author(s)
  Shinsuke Hashida, Shinichi Toyooka, Tomoaki Ohtsuka, Ken Suzawa, Kazuhiko Shien, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyosh
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego, California, U.S.A
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25293302
[Presentation] Down-regulation of microRNA-34 induces cell proliferation and invasion of human mesothelial cells.
- Author(s)
  Tanaka N, Toyooka S, Soh J, Tsukuda K, Shien K, Furukawa M, Muraoka T, Maki Y, Ueno T, Asano H, Otsuki T, Miyoshi S.
- Organizer
  103rd AACR Annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23592061
[Presentation] Anti-tumor effect of afatinib, an irreversible EGFR/HER2 dual inhibitor, in lung cancers harboring HER2 oncogene
- Author(s)
  Ken Suzawa, Shinichi Toyooka, Masakiyo Sakaguchi, Tomoaki Ohtsuka, Mototsugu Watanabe, Shinsuke Hashida, Yuho Maki, Hiromasa Yamamoto, Junichi Soh, Hiroaki Asano, Kazunori Tsukuda, Shinichiro Miyoshi
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2015-04-18 – 2015-04-22
- Data Source
  KAKENHI-PROJECT-26293318
[Presentation] 新規HER2膜貫通部領域遺伝子変異の機能解析
- Author(s)
  諏澤憲、阪口政清、山本寛斉、宗淳一、牧佑歩、橋田真輔、大塚智昭、渡邉元嗣、浅野博昭、佃和憲、三好新一郎、豊岡伸一
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26293318

1. TOYOOKA Shinichi (30397880)

# of Collaborated Projects: 17 results

# of Collaborated Products: 65 results
2. YAMAMOTO Hiromasa (40467733)

# of Collaborated Projects: 13 results

# of Collaborated Products: 38 results
3. MIYOSHI Shinichiro (00190827)

# of Collaborated Projects: 9 results

# of Collaborated Products: 38 results
4. TSUKUDA Kazunori (20346430)

# of Collaborated Projects: 8 results

# of Collaborated Products: 36 results
5. Tomida Shuta (10372111)

# of Collaborated Projects: 8 results

# of Collaborated Products: 19 results
6. ASANO Hiroaki (70534775)

# of Collaborated Projects: 7 results

# of Collaborated Products: 30 results
7. 阪口政清 (70379840)

# of Collaborated Projects: 7 results

# of Collaborated Products: 11 results
8. 諏澤憲 (90839713)

# of Collaborated Projects: 7 results

# of Collaborated Products: 12 results
9. SHIEN Kazuhiko (30708079)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
10. 須田健一 (30631593)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
11. 光冨徹哉 (70209807)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. OHTSUKA Tomoaki

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
13. MATSUDA Fumihiko (50212220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 片山博志 (90713975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 宮原信明 (70335610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 津谷康大 (10534985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小原秀太 (20813926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 濱田顕 (80772954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MURAOKA Takayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. CHEN Haiyang

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. WATANABE Masami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. SHIEN Tadahiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 山本健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 瀧川奈義夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 市原英基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 木浦勝行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Soh Junichi 宗 淳一

SOH Junichi 宗 淳一

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Basic Research for Elucidating and Overcoming the Mechanisms of Progression of Early-Stage Lung AdenocarcinomaPrincipal Investigator

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Targeted therapy for the patient with KRAS mutant lung cancerPrincipal Investigator

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Development of a new treatment strategy for HER2-alterated lung cancerPrincipal Investigator

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Novel therapeutic method for HER2 active cancer focusing on HER2 novel binding molecule cytokeratin 19Principal Investigator

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Soh Junichi 宗淳一

SOH Junichi 宗淳一