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GOTO Yuji  後藤 友二

ORCIDConnect your ORCID iD *help
Researcher Number 70362522
Other IDs
Affiliation (Current) 2025: 東邦大学, 理学部, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 東邦大学, 理学部, 教授
2019 – 2022: 東邦大学, 理学部, 准教授
2014 – 2015: 中部大学, 生命健康科学部, 助手
2012 – 2015: 東邦大学, 理学部, 講師
2007 – 2012: Chubu University, 生命健康科学部, 助手
2005 – 2006: 京都大学, 医学研究科, 科学技術振興助手
2004: 京都大学, 医学研究科, 研究員(科学技術振興)(常勤形態)
Review Section/Research Field
Principal Investigator
Genetics/Genome dynamics / Basic Section 43050:Genome biology-related / Biological Sciences
Except Principal Investigator
Risk sciences of radiation/Chemicals / Basic Section 45010:Genetics-related / Hygiene / Genome biology / Laboratory animal science
Keywords
Principal Investigator
X染色体不活性化 / ヘテロクロマチン / クロマチン構造 / 染色体放出 / 比較ゲノミクス / ゲノム解読 / EIF2S3 / KLHL15 / Matrix attachment region / 不活性X染色体 … More / 転写制御 / ヒストン修飾 / 不活性化 / X染色体 / 発現 / ゲノム機能 / ヒストンメチル化 / ヘテロクロマチン化 / アンチセンスRNA / Xist / escape gene … More
Except Principal Investigator
ヌタウナギ / 次世代シーケンシング / ゲノム再編成 / 染色体放出 / 遺伝子改変マウス / 飲用井戸水 / 井戸水 / 皮膚癌 / RET / バングラデシュ / 国際研究者交流 / ヒ素 / 内部領域欠失 / リシークエンス / リシーケンス / NGSデータ / Hi-C解析 / 染色体レベルゲノム配列構築 / 染色体末端切除 / DNA鎖内部欠失 / メラニン / 内耳性難聴 / ラセン神経節 / 先天性難聴 / 加齢性難聴 / 感音性難聴 / 騒音性難聴 / シグナル伝達 / 感音難聴 / 騒音 / 分子標的療法 / 色素細胞 / 難聴 / 労働衛生学 / 環境ストレス / 比較ゲノミクス / 次世代シーケンサー / 全ゲノム解析 / 体細胞ゲノム / 生殖細胞ゲノム / 比較ゲノム / 全ゲノム / 浄化剤 / 飲用水 / 発癌毒性 / 元素 / Placental Growth Factor / 疫学 / 発癌リスク / 疾患モデル動物 / アメリカ / ドイツ / シンガポール / フランス / 加齢性白髪 / 発症機構 / 加齢 / モデルマウス / 国際情報交換 / メラノサイト / 白髪 / モデル動物 / matrix metalloproteinase / アジア / 抗酸化剤 / ICP-MS / 重金属 / マレーシア / ベトナム / 癌遺伝子 / システイン / 癌遺伝子産物 / 発癌 Less
  • Research Projects

    (11 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (11 People)
  •  Genome assembly of Myxine garmani and Comparative genome Analysis of Three Related Species for the understanding of chromosome elimination in hagfish species.Principal Investigator

    • Principal Investigator
      後藤 友二
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43050:Genome biology-related
    • Research Institution
      Toho University
  •  A chromosome-level assembly of somatic and germline genomes in a Japanese hagfish, Eptatretus burgeri

    • Principal Investigator
      KUBOTA Souichirou
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 45010:Genetics-related
    • Research Institution
      Toho University
  •  Comparative genomics of germline and somatic genomes in Eptatretus burgeri through NGS

    • Principal Investigator
      KUBOTA Souichirou
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Genome biology
    • Research Institution
      Toho University
  •  Cancer prevention based on the review for pollution of well drinking water in Asia

    • Principal Investigator
      Kato Masashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Nagoya University
  •  Development of a model mouse line for hair graying

    • Principal Investigator
      MASASHI Kato
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Nagoya University
      Chubu University
  •  Chromatin structure and nuclear territories of the intergenic region between inactivated and escape genes on human inactive X chromosome.Principal Investigator

    • Principal Investigator
      GOTO Yuji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Genetics/Genome dynamics
    • Research Institution
      Chubu University
  •  Analysis of arsenic-mediated carcinogenesis and development of a preventive therapy targeting modulation for three-dimensional structure of oncogene products.

    • Principal Investigator
      KATO Masashi
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Nagoya University
      Chubu University
  •  Development of preventive therapy of no-se-induced hearing loss through clarifying its mechanism

    • Principal Investigator
      KATO MASASHI (KATO Masashi)
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hygiene
    • Research Institution
      Chubu University
  •  不活性X染色体上で不活性化を免れる領域のクロマチン構造の解析Principal Investigator

    • Principal Investigator
      後藤 友二
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Genetics/Genome dynamics
    • Research Institution
      Chubu University
      Kyoto University
  •  不活性X染色体上で不活性化を免れる領域と近傍領域のクロマチン構造の比較解析Principal Investigator

    • Principal Investigator
      後藤 友二
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  膜透過化細胞を用いたinvitroでのX染色体不活性化の誘導とその作用機構の解析Principal Investigator

    • Principal Investigator
      後藤 友二
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Genetics/Genome dynamics
    • Research Institution
      Kyoto University

All 2015 2013 2012 2011 2010 2008 2005 2004

All Journal Article Presentation Book Patent

  • [Book] バイオマスターシリーズ 転写研究 集中マスター2005

    • Author(s)
      後藤 友二
    • Total Pages
      172
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16770003
  • [Journal Article] RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy.2012

    • Author(s)
      Ya manoshita O Kato M
    • Journal Title

      Dermatol Res Pract.

      Volume: 2012 Pages: 354191-354191

    • DOI

      10.1155/2012/354191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590558, KAKENHI-PROJECT-22700457, KAKENHI-PROJECT-22780128, KAKENHI-PROJECT-22791041, KAKENHI-PROJECT-23650241
  • [Journal Article] RAS/RAF/MEK/ERK and PI3K/PTEN/AKT2012

    • Author(s)
      Yajima I, Kumasaka MY, Thang ND, Goto Y, Takeda K, Yamanoshita O, Iida M, Ohgami N, Tamura H, Kawamoto Y, and Kato M.
    • Journal Title

      Signaling in Malignant Melanoma Progression and Therapy.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] c-Ret-mediated hearing losses.2012

    • Author(s)
      Ohgami N, Tamura H, Ohgami K, Iida M, Yajima I, Kumasaka MY, Goto Y, Sone M, Nakashima T, and Kato M.
    • Journal Title

      International Journal of Clinical and Experimental Pathology.

      Volume: 5 Pages: 23-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.2011

    • Author(s)
      Kato M, Kumasaka MY, Takeda K, Hossain K, Iida M, Goto Y, Ohgami N.
    • Journal Title

      Toxcol In Vitro

      Volume: 25 Pages: 623-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406003
  • [Journal Article] Sunlight exposure-mediated DNA damage in young adults. Cancer Epidemiol Biomarkers Prev2011

    • Author(s)
      Kato M, Iida M, et al
    • Journal Title

      American Association for Cancer Research

      Volume: 20(8) Issue: 8 Pages: 1622-1628

    • DOI

      10.1158/1055-9965.epi-11-0228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22780128, KAKENHI-PROJECT-22791041, KAKENHI-PROJECT-23650241
  • [Journal Article] Antioxidative effects of cherry leaves extract on tert-butyl hydroperoxide-mediated cytotoxicity through regulation of thioredoxin-2 protein expression level.2011

    • Author(s)
      Taguchi N, Uemura N, Goto Y, Sakura M, Hara K, Niwa M, Iida M, Yanagishita T, Watanabe D, Kato M.
    • Journal Title

      J Toxicol Environ Health A in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406003
  • [Journal Article] L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects2011

    • Author(s)
      Kato M, Kumasaka MY, Takeda K, Hossain K, Iida M, et al
    • Journal Title

      Toxicol In Vitro, Elsevier

      Volume: 25(3) Issue: 3 Pages: 623-629

    • DOI

      10.1016/j.tiv.2010.12.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22780128, KAKENHI-PROJECT-22791092, KAKENHI-PROJECT-23650241
  • [Journal Article] L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.2011

    • Author(s)
      Kato M, Kumasaka MY, Takeda K, HossainK, Iida M, Yajima I, Goto Y, and Ohgami N.
    • Journal Title

      Toxicology In Vitro.

      Volume: 25 Pages: 623-629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.2011

    • Author(s)
      Kato M, Kumasaka MY, Takeda K, Hossain K, Iida M, Yajima I, Goto Y, Ohgami N.
    • Journal Title

      Toxcol In Vitro

      Volume: 25 Pages: 623-629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406003
  • [Journal Article] Antioxidative effects of cherry leaves extract on tert-butyl hydroperocide-mediated cytotoxicity through regulation of thioredoxin-2 protein expression levels2011

    • Author(s)
      Taguchi N, Uemura N, Goto Y, Sakura M, Hara K, Niwa M, Iida M, Yanagishita T, Watanabe D, Kato M
    • Journal Title

      J Toxicol Environ Health A

      Volume: 74 Issue: 18 Pages: 1240-7

    • DOI

      10.1080/15287394.2011.570229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008, KAKENHI-PROJECT-22780128, KAKENHI-PROJECT-23650241
  • [Journal Article] Molecular Network Associated with MITF in Skin Melanoma Development and Progression.2011

    • Author(s)
      Ya manoshita O Kato M
    • Journal Title

      J Skin Cancer.

      Volume: 2011 Pages: 730170-730170

    • DOI

      10.1155/2011/730170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590558, KAKENHI-PROJECT-22700457, KAKENHI-PROJECT-22770008, KAKENHI-PROJECT-22780128, KAKENHI-PROJECT-22791041, KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23650241
  • [Journal Article] Antioxidative effects of cherry leaves extract on tert-butyl hydroperoxide-mediated cytotoxicity through regulation of thioredoxin-2 protein expression levels.2011

    • Author(s)
      Taguchi N, Uemura N, Goto Y, Sakura M, Hara K, Niwa M, Iida M, Yanagishita T,Watanabe D, and Kato M.
    • Journal Title

      J Toxicology and Environmental Health PartA.

      Volume: 74 Pages: 1240-1247

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] Antioxidative effects of cherry leaves extract on tert-butyl hydroperoxide-mediated cytotoxicity through regulation of thioredoxin-2protein expression level2011

    • Author(s)
      Taguchi N, Uemura N, Goto Y, Sakura M, Hara K, Niwa M, Iida M, Yanagishita T, Watanabe D, Kato M
    • Journal Title

      Journal of Toxicology and Environmental Health, Part A

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] L-cysteine as a regulator for arsenic-mediated cancer- promoting and anti-cancer effects.2011

    • Author(s)
      Kato M, Kumasaka MY, Takeda K, Hossain K, Iida M, Goto Y, Ohgami N.
    • Journal Title

      Toxcol In Vitro 25

      Pages: 623-629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406003
  • [Journal Article] Sunlight exposure-mediated DNA damage in young adults2011

    • Author(s)
      Kato M, Iida M, Goto Y, Kondo T, Yajima I
    • Journal Title

      Cancer Epidemiol Biomarkers Prev

      Volume: 20 Pages: 1622-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects2011

    • Author(s)
      Kato M, Kumasaka MY, Takeda K, Hossain K, Iida M, Goto Y, Ohgami N
    • Journal Title

      Toxcol In Vitro 25(3)

      Pages: 623-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Journal Article] Molecular network associated with MITF in skin melanoma development and progression.2011

    • Author(s)
      Yajima I, Kumasaka MY, Thang ND, Goto Y,Takeda K, Iida M, Ohgami N, Tamura H, Yamanoshita O, Kawamoto Y, Furukawa K, and Kato M.
    • Journal Title

      Journal of skin cancer.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] Sunlight exposure-mediated DNA damage in young adults.2011

    • Author(s)
      Kato M, Iida M, Goto Y, Kondo T, andYajima I.
    • Journal Title

      Cancer Epidemiology and BiomarkersPreview.

      Volume: 20 Pages: 1622-1688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects.2011

    • Author(s)
      Kato M, Kumasaka MY, Takeda K, Hossain K, Iida M, Goto Y, Ohgami N.
    • Journal Title

      Toxcol In Vitro

      Volume: 25 Pages: 623-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390168
  • [Journal Article] Antioxidative effects of cherry leaves extract on tert-butyl hydroperoxide-mediated cytotoxicity through regulation of thioredoxin-2 protein expression level.2011

    • Author(s)
      TaguchiN, UemuraN, GotoY, SakuraM, HaraK, NiwaM, IidaM, YanagishitaT, WatanabeD, KatoM.
    • Journal Title

      J Toxicol Environ Health A

      Volume: 74(18) Pages: 1240-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406003
  • [Journal Article] L-cysteine as a regulator for arsenic-mediated cancer-promoting and anti-cancer effects2010

    • Author(s)
      Kato M, Kumasaka M, Takeda K, Hossain K, Iida M, Yajima I, Goto Y, Ohgami N
    • Journal Title

      Toxicology in Vitro

      Volume: 25 Pages: 623-629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Journal Article] Arsenic enhances matrix metalloproteinase-14 expression in fibroblasts.2008

    • Author(s)
      Kato M, Hossain K, Iida M, Sato H, Uemura N, Goto Y
    • Journal Title

      J Toxicol Environ Healt A

      Volume: 71(16) Pages: 1053-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20406003
  • [Journal Article] Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of polycomb group complexes.2004

    • Author(s)
      Umlauf, D., Goto, Y., Cao, R., Cerqueira, F., Eagshal, A., Zang, Y., Feil, R.
    • Journal Title

      Nature Genetics 36・12

      Pages: 1296-1300

    • Data Source
      KAKENHI-PROJECT-16011228
  • [Journal Article] Imprinting along the Kcngl domain on mouse chromosome 7 involves repressive histone methylation and recruitment of polycomb group comnlexes.2004

    • Author(s)
      Umlauf, D., Goto, Y., Cao, R., Cerqueira, F., Eagshal, A., Zang.Y., Feil, R.
    • Journal Title

      Nature Genetics 36・12

      Pages: 1296-1300

    • Data Source
      KAKENHI-PROJECT-16770003
  • [Patent] メラノーマ特異的バイオマーカー及びその利用2015

    • Inventor(s)
      加藤昌志、矢嶋伊知朗、武田湖州恵、後藤友二
    • Industrial Property Rights Holder
      名古屋大学と中部大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-058692
    • Filing Date
      2015-03-20
    • Data Source
      KAKENHI-PROJECT-24406002
  • [Presentation] 不活性化を免れる遺伝子と不活性化される遺伝子の境界領域のクロマチン構造2013

    • Author(s)
      後藤 友二
    • Organizer
      哺乳動物X染色体研究会
    • Place of Presentation
      北海道大学 札幌
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] 不活性化を免れる遺伝子と不活性化される遺伝子の境界領域のクロマチン構造2013

    • Author(s)
      後藤友二
    • Organizer
      哺乳動物X染色体研究会
    • Place of Presentation
      北大、札幌
    • Year and Date
      2013-03-23
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] 不活性化を免れる遺伝子と不活性化される遺伝子の境界領域のクロマチン構造と転写制御2012

    • Author(s)
      後藤 友二
    • Organizer
      日本遺伝学会 第84回大会
    • Place of Presentation
      九州大学 福岡
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] 不活性化を免れる遺伝子と不活性化される遺伝子の境界領域のクロマ チン構造と転写制御2012

    • Author(s)
      後藤友二
    • Organizer
      日本遺伝学会第84回大会
    • Place of Presentation
      九大、福岡
    • Year and Date
      2012-09-25
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] 不活性化を免れる遺伝子EIF2S3上流にあるクロマチン構造の解析II2011

    • Author(s)
      後藤友二
    • Organizer
      日本遺伝学会第83回大会
    • Place of Presentation
      京都大学(京都)
    • Year and Date
      2011-09-20
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] 不活性化を免れる遺伝子 EIF2S3 上流にあるクロマチン構造の解析 II2011

    • Author(s)
      後藤友二 、加藤昌志
    • Organizer
      日本遺伝学会第83回大会
    • Place of Presentation
      京大、京都
    • Year and Date
      2011-09-20
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] 不活性化を免れる遺伝子 EIF2S3 上流にあるクロマチン構造の解析2010

    • Author(s)
      後藤友二 、加藤昌志
    • Organizer
      日本遺伝学会第82回大会
    • Place of Presentation
      北大、札幌
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] メラノーマ自然発症モデルマウスを用いた癌抑制遺伝子のスクリーニングと機能解析2010

    • Author(s)
      後藤友二 、加藤昌志
    • Organizer
      日本分子生物学会第33回大会
    • Place of Presentation
      ポートアイランド、神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] 不活性化を免れる遺伝子EIF2S3上流にあるクロマチン構造の解析2010

    • Author(s)
      後藤友二
    • Organizer
      日本遺伝学会 第82回大会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2010-09-20
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] メラノーマ自然発症モデルマウスを用いた癌抑制遺伝子のスクリーニングと機能解析2010

    • Author(s)
      後藤友二
    • Organizer
      第33回日本分子生物学会年会
    • Place of Presentation
      ポートアイランド(神戸)
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22770008
  • [Presentation] ヒト不活性X染色体上における不活性回避遺伝子周辺のクロマチン構造2008

    • Author(s)
      後藤 友二
    • Organizer
      日本衛生学会 第78回総会
    • Place of Presentation
      熊本市民会館
    • Year and Date
      2008-03-31
    • Data Source
      KAKENHI-PROJECT-18770006
  • 1.  KATO Masashi (10281073)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 2.  OHGAMI Nobutaka (80424919)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 3.  YAMANOSHITA Osamu (50424924)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  KUBOTA Souichirou (30277347)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KAWAMOTO Yoshiyuki (10410664)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  TAKEDA Kozue (80345884)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  YAJIMA Ichiro (80469022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KUWATA Yusuke (00772708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  伊田 みちる (80393148)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 10.  浅井 直也 (80273233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  飯田 真智子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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