Takamiya Rina 高宮里奈

… Alternative Names

TAKAMIYA Rina 高宮里奈

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Researcher Number	70365419
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 兵庫医科大学, 医学部, 講師 2018 – 2023: 東京大学, 大学院医学系研究科(医学部), 特任助教 2013 – 2017: 札幌医科大学, 医学部, 助教 2012: 独立行政法人理化学研究所, その他部局等, 研究員 2011 – 2012: 独立行政法人理化学研究所, 糖鎖認識研究チーム, 基幹研究所研究員 2009 – 2010: Keio University, 医学系研究科, 特任研究員(常勤) 2008: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Tumor biology / Respiratory organ internal medicine / Basic Section 50010:Tumor biology-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator リピドミクス解析 / 酸化ストレス / COPD / ミトコンドリア / ホスファチジルコリン / 肺線維症 / がん微小環境 / 糖鎖抗原 / 糖鎖 / マクロファージ … More / 代謝 / メタボローム解析 / 肺がん / II 型肺胞上皮細胞 / リン脂質分解酵素 / コリン / 小胞体 / 肺癌 / Nrf2 / COX-2 / 間質性肺炎 / 線維化 / 脂質代謝 / Phophalipase A2 / ブレオマイシン / 肺線維化 / リピドミクス / 肺サーファクタント / 特発性肺線維症 / 肺胞微石症 / エピゲノム解析 / 細胞周期 / 三次元培養 / メチル化解析 / メタボローム / メチル化 / がん糖鎖 / がん / 低酸素 / SOD-1 / マクロフィージ / SOD1 / 脂質メディエーター / 活性酸素種 / 慢性閉塞性肺疾患 / 抗炎症性脂質メディエーター / 代謝解析 / タバコ / coPD / ペントースリン酸回路 / 活性酸素 / 赤血球 / 白血球 … More Except Principal Investigator 肺胞マクロファージ / ナトリウムリン酸共輸送体 / 動物実験モデル / 治療法開発 / オミクス解析 / 希少肺疾患 / リン酸トランスポーター / 肺胞微石症 Less

Role of Membrane Phospholipid Metabolism in Cancer MalignancyPrincipal Investigator
- Principal Investigator
  
  高宮里奈
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Hyogo Medical University
Elucidation of pathogenesis of interactable lung diseases associated with dysregulated lipid metabolismPrincipal Investigator
- Principal Investigator
  
  高宮里奈
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
Exploring the Molecular Pathogenesis of Pulmonary Alveolar Microlithiasis and Developing Novel Therapeutic Approaches Using Integrated Omics Analysis
- Principal Investigator
  
  SAITO ATSUSHI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Sapporo Medical University
The quality of lipid component of pulmonary surfactant in lung diseasesPrincipal Investigator
- Principal Investigator
  
  Takamiya RIna
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
Elucidating the mechanism of construction of intratumor heterogeneity by tumor-associated glycanPrincipal Investigator
- Principal Investigator
  
  Takamiya Rina
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
  Sapporo Medical University
Regulation of tumor microenvironment by tumor-associated sialyl-Tn antigenPrincipal Investigator
- Principal Investigator
  
  Takamiya RIna
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Sapporo Medical University
Analysis of Nucleotide sugar: Association with pathogenesis of COPD in LeukocytePrincipal Investigator
- Principal Investigator
  
  TAKAMIYA Rina
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The Institute of Physical and Chemical Research
  Osaka University
The Metabolome Analysis: Association with pathogenesis of COPD in LeukocytePrincipal Investigator
- Principal Investigator
  
  TAKAMIYA Rina
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Keio University

[Book] 分子呼吸器病2019
- Author(s)
  高宮里奈、前野敏孝、有木茂、齋藤充史、高橋弘毅、黒木由夫、高橋素子
- Publisher
  先端医学社
- ISBN
  9784865503975
- Data Source
  KAKENHI-PROJECT-16K07123
[Book] The Lung2013
- Author(s)
  大坪和明、高宮里奈、谷口直之
- Total Pages
  4
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25430123
[Journal Article] Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups2023
- Author(s)
  Hirabayashi T, Kawaguchi M, Harada S, Mouri M, Takamiya R, Miki Y, Sato H, Taketomi Y, Yokoyama K, Kobayashi T, Tokuoka SM, Kita Y, Yoda E, Hara S, Mikami K, Nishito Y, Kikuchi N, Nakata R, Kaneko M, Kiyonari H, Kasahara K, Aiba T, Ikeda K, Soga T, Kurano M, Yatomi Y, Murakami M
- Journal Title
  
  Cell Rep
  
  Volume: 42 Issue: 2 Pages: 111940-111940
- DOI
  10.1016/j.celrep.2022.111940
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08315, KAKENHI-PROJECT-22K06577, KAKENHI-PROJECT-19K07042, KAKENHI-PROJECT-22K08229
[Journal Article] Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti‐inflammatory lipid N‐acylethanolamine.2022
- Author(s)
  Liang Luyiyun、Takamiya Rina、Miki Yoshimi、Heike Kanako、Taketomi Yoshitaka、Sugimoto Nao、Yamaguchi Midori、Shitara Hiroshi、Nishito Yasumasa、Kobayashi Tetsuyuki、Hirabayashi Tetsuya、Murakami Makoto
- Journal Title
  
  The FASEB Journal
  
  Volume: 36 Issue: 5
- DOI
  10.1096/fj.202101958r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-21K08315, KAKENHI-PROJECT-22K06577, KAKENHI-PROJECT-22K08229, KAKENHI-PROJECT-19K07042, KAKENHI-PROJECT-19K08597, KAKENHI-PROJECT-20H05691, KAKENHI-PROJECT-18K06978
[Journal Article] Segregated functions of two cytosolic phospholipase A2 isoforms (cPLA2α and cPLA2ε) in lipid mediator generation2022
- Author(s)
  Murakami M, Takamiya R, Miki Y, Sugimoto N, Nagasaki Y, Suzuki-Yamamoto T, Taketomi Y.
- Journal Title
  
  Biochemical Pharmacology
  
  Volume: 203 Pages: 115176-115176
- DOI
  10.1016/j.bcp.2022.115176
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06577, KAKENHI-PROJECT-22K08229, KAKENHI-PROJECT-21K19664, KAKENHI-PROJECT-21J15268, KAKENHI-PROJECT-19K07042, KAKENHI-PROJECT-19K08597, KAKENHI-PROJECT-20H05691, KAKENHI-PROJECT-23K22225
[Journal Article] Acrolein in cigarette smoke attenuates the innate immune responses mediated by surfactant protein D2020
- Author(s)
  Takamiya Rina、Takahashi Motoko、Maeno Toshitaka、Saito Atsushi、Kato Masaki、Shibata Takahiro、Uchida Koji、Ariki Shigeru、Nakano Miyako
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1864 Issue: 11 Pages: 129699-129699
- DOI
  10.1016/j.bbagen.2020.129699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08597, KAKENHI-PROJECT-19H02922, KAKENHI-PROJECT-18K06115, KAKENHI-PROJECT-17H06170
[Journal Article] Disruption of the structural and functional features of surfactant protein A by acrolein in cigarette smoke2017
- Author(s)
  Takamiya Rina、Uchida Koji、Shibata Takahiro、Maeno Toshitaka、Kato Masaki、Yamaguchi Yoshiki、Ariki Shigeru、Hasegawa Yoshihiro、Saito Atsushi、Miwa Soichi、Takahashi Hiroki、Akaike Takaaki、Kuroki Yoshio、Takahashi Motoko
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 8304-8304
- DOI
  10.1038/s41598-017-08588-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07123, KAKENHI-PROJECT-17K07339, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-16K19460, KAKENHI-PROJECT-16K19461, KAKENHI-PROJECT-16H04758
[Journal Article] Surfactant protein A inhibits growth and adherence of uropathogenic Escherichia coli to protect the bladder from infection.2017
- Author(s)
  Hashimoto J., Takahashi M., Satio A., Murata M., Kurimura Y., Nishitani C., Takamiya R., Uehara Y., Hasegawa Y., Hiyama Y., Sawada N., Takahashi S., Masumori N., Kuroki Y., Ariki S.
- Journal Title
  
  J. Immunol.
  
  Volume: 198 Issue: 7 Pages: 2898-2905
- DOI
  10.4049/jimmunol.1502626
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440058, KAKENHI-PROJECT-16K07123, KAKENHI-PROJECT-16K19460, KAKENHI-PROJECT-16K19461, KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-17K07339
[Journal Article] Surfactant protein A down-regulates epidermal growth factor receptor by mechanisms different from those of surfactant protein D2017
- Author(s)
  Yoshihiro Hasegawa, Motoko Takahashi, Shigeru Ariki, Atsushi Saito, Yasuaki Uehara, Rina Takamiya, Koji Kuronuma, Hirofumi Chiba, Yuji Sakuma, Hiroki Takahashi, Yoshio Kuroki
- Journal Title
  
  J Bill Chem
  
  Volume: 292 Issue: 45 Pages: 18565-18576
- DOI
  10.1074/jbc.m117.800771
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07123, KAKENHI-PROJECT-17K07339, KAKENHI-PROJECT-16K19460, KAKENHI-PROJECT-16K19461
[Journal Article] Surfactant Protein A (SP-A) and SP-A-derived Peptide Attenuate Chemotaxis of Mast Cells Induced by Human β-defensin 3.2017
- Author(s)
  Uehara Y., Takahashi M., Murata M., Saito A., Takamiya R., Hasegawa Y., Kuronuma K., Chiba H., Hashimoto J., Sawada N., Takahashi H., Kuroki Y., Ariki S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 485 Issue: 1 Pages: 107-112
- DOI
  10.1016/j.bbrc.2017.02.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440058, KAKENHI-PROJECT-16K07123, KAKENHI-PROJECT-16K19460, KAKENHI-PROJECT-16K19461, KAKENHI-PROJECT-16K08693, KAKENHI-PROJECT-17K07339, KAKENHI-PROJECT-15K09181
[Journal Article] Surfactant protein D inhibits activation of non-small cell lung cancer-associated mutant EGFR and affects clinical outcomes of patients2017
- Author(s)
  Umeda Y、Hasegawa Y、Otsuka M、Ariki S、Takamiya R、Saito A、Uehara Y、Saijo H、Kuronuma K、Chiba H、Ohnishi H、Sakuma Y、Takahashi H、Kuroki Y、Takahashi M
- Journal Title
  
  Oncogene
  
  Volume: 36 Issue: 46 Pages: 6432-6445
- DOI
  10.1038/onc.2017.253
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07123, KAKENHI-PROJECT-17K07339, KAKENHI-PROJECT-16K19460, KAKENHI-PROJECT-16K19461
[Journal Article] Surfactant protein D suppresses lung cancer progression by downregulation of epidermal growth factor signaling.2015
- Author(s)
  Hasegawa Y, Takahashi M, Ariki S, Asakawa D, Tajiri M, Wada Y, Yamaguchi Y, Nishitani C, Takamiya R, Saito A, Uehara Y, Hashimoto J, Kurimura Y, Takahashi H, Kuroki Y.
- Journal Title
  
  Oncogene
  
  Volume: 34 Pages: 838-845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430123
[Journal Article] The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin β1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway2014
- Author(s)
  Takamiya R, Takahashi M, Uehara Y, Ariki S, Hashimoto J, Hasegawa Y, Kuroki Y
- Journal Title
  
  Biochem Biophys Res Comun
  
  Volume: 454 Pages: 364-368
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430123
[Journal Article] The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-β secretion from monocytes/macrophages through the DAP12-Syk pathway2013
- Author(s)
  Takamiya R, Ohtsubo K, Takamatsu S, Taniguchi N, Angata T
- Journal Title
  
  Glycobiology
  
  Volume: 23 Pages: 178-187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790755
[Journal Article] The interaction between Siglec-15 and tumor-associated sialyl-Tn antigen enhances TGF-β secretion from monocytes/macrophages through the DAP12-Syk pathway.2013
- Author(s)
  Rina Takamiya
- Journal Title
  
  Glycobiology
  
  Volume: 23 Issue: 2 Pages: 178-187
- DOI
  10.1093/glycob/cws139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790755, KAKENHI-PROJECT-23790363, KAKENHI-PROJECT-25430123
[Journal Article] Suppression of heregulin beta signaling by single N-glycan deletion mutant of soluble ErbB32013
- Author(s)
  Takahashi M, Hasegawa Y, Ikeda Y, Wada Y, Tajiri M, Ariki S, Takamiya R, Nishitani C, Araki M, Yamaguchi Y, Taniguchi N, Kuroki Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 46 Pages: 32910-32921
- DOI
  10.1074/jbc.m113.491902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390081, KAKENHI-PROJECT-23550099, KAKENHI-PROJECT-24591173, KAKENHI-PROJECT-25430123, KAKENHI-PROJECT-25461194
[Journal Article] Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma2012
- Author(s)
  Miyata J, Fukunaga K, Iwamoto R, Isobe Y, Niimi K, Takamiya R, Takihara T, Tomomatsu K, Suzuki Y, Ogum, Sayama K, Arai H, Betsuyaku T, Arita M, Asano K
- Journal Title
  
  J Allergy Clin Immun
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790755
[Journal Article] Annexin V decreases PS-1 mediated macrophage efferocytosis and deteriorates elastase-induced pulmonary emphysema in mice2012
- Author(s)
  Yoshida S, Minematsu N, Chubachi S, Nakamura H, Miyazaki M, Tsuduki K, Takahashi S, Miyasho T, Iwabuchi T, Takamiya R, Tateno H, Mouded M, Shapiro SD, Asano K, Betsuyaku T
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol
  
  Volume: 303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790755
[Journal Article] Resolvin E1 maintains macrophage function under cigarette smoke-induced oxidative stress2012
- Author(s)
  Takamiya R, Fukunaga K, Arita M, Miyata J, Seki H, Minematsu N, Suematsu M, Asano K
- Journal Title
  
  FEBS Open Bio
  
  Volume: 2 Pages: 328-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790755
[Journal Article] Carbon black nanoparticles enhance bleomycin-induced lung inflammatory and fibrotic changes in mice2011
- Author(s)
  Kamata H, Tasaka S, Inoue K, Miyamoto K, Nakano Y, Shinoda H, Kimizuka Y, Fujiwara H, Ishii M, Hasegawa N, Takamiya R, Fujishima S, Takano H, Ishizaka A,
- Journal Title
  
  Exp Biol Med (Maywood)
  
  Volume: 236 Pages: 315-324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790755
[Journal Article] Levy The Anti-Inflammatory and Proresolving Mediator Resolvin E1 Protects Mice from Bacterial Pneumonia and Acute Lung Injury2010
- Author(s)
  Hiroyuki Seki, Koichi Fukunaga, Arita, Makoto H, iroyuki Arai, Hiroki Nakanish, Ryo Taguchi, Toru Miyasho, Rina Takamiya, Koichiro Asano, Akitochi Ishizaka, Jyunzo Takeda, Bruce D
- Journal Title
  
  The Journal of Immunology 184
  
  Pages: 836-843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Journal Article] The anti-inflammatory and pro-resolving mediator Resolvin E1 protects mice from bacterial pneumonia and acute lung injury2010
- Author(s)
  Seki H, Fukunaga K, Arita M, Arai H, Nakanishi H, Taguchi R, Miyasho T, Takamiya R, Asano K, Ishizaka A, Takeda J, Levy BD
- Journal Title
  
  Journal of Immunology 184(2)
  
  Pages: 836-843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Journal Article] High mobility group box 1 protein in the absence of HO-1 : Role during endotoxemia in mice2009
- Author(s)
  Takamiya R, Hung CC, Hall SR, Fukunaga K, Nagaishi T, Maeno T, Macias AA, Owen CA, Fredenburgh LE, Ishizaka A, Blumberg RS, Baron RM, Perrella MA
- Journal Title
  
  American Journal of Respiratory Cell and Morecular Biology 41
  
  Pages: 129-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Journal Article] High Mobility Group Box 1 Contributes to Lethality of Endotoxemia in Heme Oxygenase-1 Deficient Mice2009
- Author(s)
  Rina Takamiya
- Journal Title
  
  Am J Respir Cell Mol Biol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Journal Article] Perrella High-mobility group box 1 contributes to lethality of endotoxemia in heme oxygenase-1-deficient mice2009
- Author(s)
  Rina Takamiya, Chi-Chih Hung, Sean R. Hall, Koichi Fukunaga, Takashi Nagaishi, Toshitaka Maeno, Caroline Owen, Alvaro A. Macias, Laura E. Fredenburgh, Akitoshi Ishizaka, Richard S. Blumberg, Rebecca M. Baron, Mark A.
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology 41
  
  Pages: 129-135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Journal Article] Rescue of Anemia and Autoimmune Responses in Cu, Zn-Superoxide Dismutase Gene (SOD1)-Deficient Mice by Transgenic Expression of Human SOD1 in Erythrocytes2009
- Author(s)
  Iuchi Y, Okada F, Takamiya R, Kibe N, Tsunoda S, Nakajima S, Toyoda K, Nagae R, Suematsu M, Soga T, Uchida K, Fujii J
- Journal Title
  
  Biochemical Journal 422
  
  Pages: 313-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Journal Article] Rescue of anaemia and autoimmune responses in SOD1-deficient mice by transgenic expression of human SOD1 in erythrocytes2009
- Author(s)
  Yoshito Iuchi, Futoshi Okada, Rina Takamiya, Noriko Kibe, Satoshi Tsunoda, Osamu Nakajima, Kazuyo Toyoda, Ritsuko Nagae, Makoto Suematsu, Tomoyoshi Soga, Koji Uchida, Jyunichi Fujii
- Journal Title
  
  Biochemical Journal 422
  
  Pages: 313-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Journal Article] High mobility group A1 protein mediates human nitric oxide synthase 2 gene expression2008
- Author(s)
  Rina Takamiya, Rebecca M. Baron, Shaw-Fang Yet, Matthew D. Layne, Mark A. Perrella
- Journal Title
  
  FEBS Letters 582
  
  Pages: 810-814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Journal Article] High mobility group Al protein mediates human nitric oxide synthase 2 geneexpression2008
- Author(s)
  Rina Takamiya
- Journal Title
  
  FEBS Lett 582
  
  Pages: 810-814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] リン脂質分解酵素PNPLA6のがん化、細胞老化機構への関与2023
- Author(s)
  高宮里奈、村上誠
- Organizer
  第９６回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K08229
[Presentation] 乾癬時増加する生理活性脂質(NAE)の産生機構と乾癬炎症抑制効果2022
- Author(s)
  高宮里奈、三木寿美、梁陸伊韻、村上誠
- Organizer
  第９５回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08597
[Presentation] 乾癬時増加する生理活性脂質(NAE)の産生機構と乾癬炎症抑制効果2022
- Author(s)
  高宮里奈、三木寿美、梁陸伊韻1、村上誠
- Organizer
  第９５回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K08229
[Presentation] The phosphate binder attenuates microlith formation and cox-2 induction in pulmonary alveolar microlithiasis.2021
- Author(s)
  Saito A, Takamiya R, Fujitani N, Ariki S, Kuronuma K, Chiba H.
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08521
[Presentation] cPLA2eは抗炎症性脂質NAEの産生に関わる2021
- Author(s)
  杉本奈央、高宮里奈、三木寿美、宇山徹、上田夏生、李賢哲、横溝岳彦、村上誠
- Organizer
  第94回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08597
[Presentation] 本邦における肺胞微石症の一症例とモデルマウスを用いた病態解析2020
- Author(s)
  齋藤充史、高宮里奈、有木茂、黒沼幸治、千葉弘文、高橋素子、高橋弘毅
- Organizer
  第60回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K08521
[Presentation] 肺胞微石症IIb型ナトリウムリン酸共輸送体(Npt2b)欠損マウスを用いた臨床応用に向けた肺胞微石症の病態解析2020
- Author(s)
  高宮里奈　三木寿美　村上誠　高橋弘毅　齋藤充史
- Organizer
  第９３回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08597
[Presentation] タバコ煙中のacroleinによる肺サーファクタントタンパク質D (SP- D)の構造、機能への影響2019
- Author(s)
  高宮里奈、有木茂、前野敏孝、齋藤充史、高橋広毅、高橋素子、中の三弥子
- Organizer
  第９２回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08597
[Presentation] The Phosphate Binder Ferric Citrate Attenuates Microlith Formation and COX-2 Induction in a Mouse Model of Pulmonary Alveolar Microlithiasis2019
- Author(s)
  Takamiya R, Miki Y, Murakami M, Takahashi H, Saito A
- Organizer
  ICBL2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08597
[Presentation] タバコ煙中のアクロレインが肺サーファクタントタンパク質D(SP-D)の構造、機能への影響2019
- Author(s)
  高宮里奈、有木茂、前野敏孝、齋藤充史、高橋広毅、高橋素子、中の三弥子
- Organizer
  第18回肺サーファクタント分子病態研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08597
[Presentation] がん糖鎖によるがん細胞内代謝リプログラミング機構の解明2018
- Author(s)
  高宮里奈、曽我朋義、鈴木拓、大坪和明
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07123
[Presentation] がん糖鎖によるがん細胞内代謝調節機構2018
- Author(s)
  高宮里奈、曽我朋義、鈴木拓、大坪和明
- Organizer
  第９１回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K07123
[Presentation] Surfactant protein A leads to monocytes differentiation through activation of cytoskeletal signaling2018
- Author(s)
  Takamiya R., Murata M., Ariki S., Saito A., Sawada N., Takahashi M., Kuroki Y.
- Organizer
  American Thoracic Society 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07123
[Presentation] タバコ煙中のアクロレインが肺サーファクタントタンパク質A(SP-A) に及ぼす影響2017
- Author(s)
  高宮里奈、内田浩二、柴田貴広、前野敏孝、加藤雅樹、山口芳樹、有木茂、長谷川喜弘、齋藤充史、前野敏孝、黒木由夫、高橋素子
- Organizer
  第３６回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-16K07123
[Presentation] がん糖鎖による腫瘍内低酸素環境におけるがん悪性化機構2017
- Author(s)
  高宮里奈、大坪和明
- Organizer
  第７６回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07123
[Presentation] タバコ煙中のアクロレインが肺サーファクタントタンパク質A (SP-A) の機能や構造に及ぼす影響2017
- Author(s)
  高宮里奈、内田浩二、柴田貴広、前野敏孝、有木茂、長谷川喜弘、齋藤充史、黒木由夫、高橋素子
- Organizer
  conbio2017
- Data Source
  KAKENHI-PROJECT-16K07123
[Presentation] タバコ煙やアクロレインが肺サーファクタントタンパク質Aに及ぼす影響2016
- Author(s)
  高宮里奈　内田浩二　柴田貴広　高橋素子　有木茂　長谷川喜弘　齋藤充史　前野敏孝　黒木由夫
- Organizer
  第８９回日本生化学会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K07123
[Presentation] がん関連糖鎖Sialyl-Tn糖鎖抗原によるがん悪性化構築メカニズムの解明2016
- Author(s)
  高宮里奈　前田賢人　田嶋彩香　藤井柊作　大坪和明
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-16K07123
[Presentation] 肺コレクチンSP-Aによる肺胞マクロファージの分化調節機構の解明2015
- Author(s)
  高宮里奈、有木茂、村田雅樹、長谷川喜弘、高橋素子、澤田典均、黒木由夫
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] がん悪性化における酸素応答制御機構の解明2015
- Author(s)
  高宮里奈、高橋素子、佐久間裕司、長谷川喜弘、有木茂、鈴木拓、黒木由夫
- Organizer
  第68回日本酸化ストレス学会学術集会
- Place of Presentation
  鹿児島県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2015-06-11
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] 低酸素誘導がん特異的糖鎖抗原によるがん悪性化機構の解明2013
- Author(s)
  高宮里奈、高松真二、安形高志、谷口直之、大坪和明
- Organizer
  平成２３年度がん若手ワークショップ
- Place of Presentation
  蓼科グランドホテル滝の湯、芽野市、長野県
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] がん関連糖鎖シアリルTn糖鎖抗原発現によるインテグリンを介したがん微小環境制御機構2013
- Author(s)
  高宮里奈、大坪和明、高松真二、安形高志、高橋素子、黒木由夫、谷口直之
- Organizer
  第８６回日本生化学会
- Place of Presentation
  パシフィコ横浜、横浜市、神奈川県
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] Regulation of tumor microenvironment by tumor-associated sialyl- Tn antigen through ROS production by immune cells2013
- Author(s)
  Rina Takamiya, Kazuaki Ohtsubo, Shinji Takamatsu, Naoyuki Taniguchi, Takashi Angata
- Organizer
  RIKEN;Max Planck Joint Research Center for Systems Chemical Biology The Second Symposium
- Place of Presentation
  RIKEN, Wako, Saitama
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] 癌関連糖鎖抗原Sialyl-Tn によるがん微小環境調節機構の解明2012
- Author(s)
  高宮里奈、大坪和明、高松真二、白土健、谷口直之、安形高志
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] 癌関連糖鎖抗原Sialyl-Tnによるがん微小環境調節機構の解明2012
- Author(s)
  高宮里奈
- Organizer
  第８５回日本生化学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Regulation of tumor microenvironment by tumor-associated sialyl-Tn antigen through ROS production by immune cells2012
- Author(s)
  Rina Takamiya
- Organizer
  The 33rd Naito Conference on Oxygen Biology: Hypoxia, oxidative stress and disease
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Regulation of tumor microenvironment by tumor-associated sialyl-Tn antigen through ROS production by immune cells2012
- Author(s)
  Takamiya R, Ohtsubo K, Takamatsu S, Taniguchi N, Angata T
- Organizer
  The 33rd Naito Conference on Oxygen Biology: Hypoxia, oxidative stress and disease
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Regulation of monocyte function by tumor associated sialyl-Tn antigen through ROS production2011
- Author(s)
  Takamiya R, Ohtsubo K, Takamatsu S, Taniguchi N, Angata T
- Organizer
  5th SFRR-ASIA, 8th ASMRM, 11th J-mit 2011
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Sialyl-Tn 抗原の認識による活性酸素種産生を伴う単球細胞株の活性化2011
- Author(s)
  高宮里奈、大坪和明、高松真二、白土健、谷口直之、安形高志
- Organizer
  第64回酸化ストレス学会
- Place of Presentation
  留寿都
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Sialyl-Tn抗原の認識による活性酸素種産生を伴う単球細胞株の活性化2011
- Author(s)
  高宮里奈、大坪和明、高松真二、白土健、谷口直之
- Organizer
  第64回酸化ストレス学会
- Place of Presentation
  留寿都
- Year and Date
  2011-07-03
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] 癌特異的糖鎖抗原Sialyl-Tnによる活性酸素種産生を伴う単球の活性化機構の解明2011
- Author(s)
  高宮里奈、大坪和明、高松真二、白土健、谷口直之、安形高志
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] 癌特異的糖鎖抗原Sialyl-Tn による活性酸素種産生を伴う単球の活性化機構の解明2011
- Author(s)
  高宮里奈、大坪和明、高松真二、白土健、谷口直之、安形高志
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] High mobility group A1 protein mediates human nitric oxide synthase 2 gene expression2010
- Author(s)
  高宮里奈
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  京都
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Cigarette smoke extract induces bisecting GlcNAc modification in RAW264.7 murine macrophage2010
- Author(s)
  高宮里奈
- Organizer
  7th International Symposium on Glycosyltransferases
- Place of Presentation
  東京
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] A deficiency of heme oxygenase-1 leads to increased baseline inflammation and enhanced expression of HMGB1 in macrophages2010
- Author(s)
  高宮里奈
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] High mobility group A1 protein mediates human nitric oxide synthase 2 gene expression2010
- Author(s)
  Takamiya R, Baron RM, Yet S-F, Layne MD, Angata T, Taniguchi N, Perrella MA
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Baron RM, Perrella MA, A deficiency of heme oxygenase-1 leads to increased baseline inflammation and enhanced expression of HMGB1 in macrophages2010
- Author(s)
  高宮里奈、永石宇司、Owen C, Hall SR, Ith B, 安形高志、谷口直之、前野敏孝
- Organizer
  日本生化学会・分子生物学会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Cigarette smoke extract induces bisecting GlcNAc modification in RAW264.7 murine macrophage2010
- Author(s)
  Takamiya R, Ohtsubo K, Takamatsu S, Nakajima K, Shirato K, Taniguchi N, Angata T
- Organizer
  7th International Symposium on Glycosyltransferases
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22790755
[Presentation] Cigarette smoke extract induces bisecting-GlcNAc modification in RAW264. 7 murine macrophage2009
- Author(s)
  Rina Takamiya
- Organizer
  20th Joint Glycobiology Meeting
- Place of Presentation
  ケルン、ドイツ
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] Cigarette smoke extract induces bisecting-G1cNAc modification in RAW26 4.7 murine macrophage2009
- Author(s)
  Takamiya R, Ohtsubo K, Takamatsu S, Taniguchi N, Angata T
- Organizer
  Japanese-Giessen-GlycoWorkshop
- Place of Presentation
  Justus-Liebig-University, Giessen, Germany
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] Cigarette smoke extract induces bisecting-GlcNAc modification in RAW264. 7 murine macrophage2009
- Author(s)
  Rina Takamiya
- Organizer
  Japanese-Giessen GlycoWorkshop
- Place of Presentation
  ギーセン、ドイツ
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] タバコ煙によるマクロファージ機能低下におけるレゾルビンE1の有用性2009
- Author(s)
  高宮里奈
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] タバコ煙によるマクロファージ機能低下におけるレゾルビンE1の有用性の検討2009
- Author(s)
  高宮里奈、福永興壱、有田誠、宮田純、末松誠、浅野浩一郎、石坂彰敏
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際展示場、神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] Cigarette smoke extract induces bisecting-G1cNAc modification in RAW26 4.7 murine macrophage2009
- Author(s)
  Takamiya R, Ohtsubo K, Takamatsu S, Taniguchi N, Angata T
- Organizer
  20th Joint Glycobiology Meeting
- Place of Presentation
  Maternushaus, Cologne, Germany
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] Circulating levels of HMGB1 are exaggerated in HO-1 null mice during endotoxemia2008
- Author(s)
  Rina Takamiya
- Organizer
  American Thoracic Society International Meeting 2008
- Place of Presentation
  トロント、カナダ
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] 網羅的代謝解析を中心としたアクロレインに曝露された赤血球の機能解明2008
- Author(s)
  高宮里奈
- Organizer
  第31回日本生化学会・分子生物学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] Circulating levels of HMGB1 are exaggerated in HO-1 null mice during endotoxemia2008
- Author(s)
  Rina Takamiya
- Organizer
  American Thoracic Society International Meeting 2008
- Place of Presentation
  カナダトロント
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20790575
[Presentation] N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin-induced tumor progression by blockade of hypoxia inducible factor-1 pathway
- Author(s)
  Takamiya R, Takahashi M, Hasegawa Y, Uehara Y, Ariki S, Hashimoto J, Kuroki Y
- Organizer
  Society for Glycobiology & Japanese Society of Carbohydrate Research 2014 Joint Meeting
- Place of Presentation
  ハワイ：アメリカ合衆国
- Year and Date
  2014-11-16 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] 肺コレクチンの単球機能への影響
- Author(s)
  高宮里奈、村田雅樹、上原康昭、有木茂、長谷川喜弘、橋本次朗、高橋素子、澤田典均、黒木由夫
- Organizer
  第８７回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] Regulation of tumor microenviroment by tumor associated sialyl-Tn antigen on integrin
- Author(s)
  Takamiya R, Takamatsu S, Angata T, Takahashi M, Kuroki Y, Taniguchi N, Ohtsubo K
- Organizer
  American Thoracic Society 2014
- Place of Presentation
  サンディエゴ：アメリカ合衆国
- Year and Date
  2014-05-06 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] 低酸素誘導がん特異的糖鎖抗原によるがん悪性化機構の解明
- Author(s)
  高宮里奈、高松真二、安形高志、高橋素子、黒木由夫、谷口直之、大坪和明
- Organizer
  第６７回日本酸化ストレス学会
- Place of Presentation
  京都
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25430123
[Presentation] がん関連糖鎖シアリルTn糖鎖抗原発現によるインテグリンを介したがん微小環境制御機構
- Author(s)
  高宮里奈、大坪和明、高松真二、高橋素子、黒木由夫、谷口直之
- Organizer
  日本生化学会北海道支部支部例会第50回記念大会
- Place of Presentation
  北海道大学、札幌市、北海道
- Data Source
  KAKENHI-PROJECT-25430123

1. SAITO ATSUSHI (00768939)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. Ohtsubo Kazuaki (30525457)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. 鈴木拓 (20381254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 藤谷直樹 (10374191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 長崎祐樹 (70985621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ARIKI Shigeru

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. TAJIRI Michiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. MIKI Yoshimi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高橋素子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 和田芳直

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 平林哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takamiya Rina 高宮 里奈

TAKAMIYA Rina 高宮 里奈

Research Projects

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Role of Membrane Phospholipid Metabolism in Cancer MalignancyPrincipal Investigator

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Elucidation of pathogenesis of interactable lung diseases associated with dysregulated lipid metabolismPrincipal Investigator

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Exploring the Molecular Pathogenesis of Pulmonary Alveolar Microlithiasis and Developing Novel Therapeutic Approaches Using Integrated Omics Analysis

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The quality of lipid component of pulmonary surfactant in lung diseasesPrincipal Investigator

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Elucidating the mechanism of construction of intratumor heterogeneity by tumor-associated glycanPrincipal Investigator

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Regulation of tumor microenvironment by tumor-associated sialyl-Tn antigenPrincipal Investigator

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Analysis of Nucleotide sugar: Association with pathogenesis of COPD in LeukocytePrincipal Investigator

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The Metabolome Analysis: Association with pathogenesis of COPD in LeukocytePrincipal Investigator

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[Book] 分子呼吸器病2019

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[Book] The Lung2013

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[Journal Article] Hepatic phosphatidylcholine catabolism driven by PNPLA7 and PNPLA8 supplies endogenous choline to replenish the methionine cycle with methyl groups2023

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[Journal Article] Group IVE cytosolic phospholipase A2 limits psoriatic inflammation by mobilizing the anti‐inflammatory lipid N‐acylethanolamine.2022

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[Journal Article] Segregated functions of two cytosolic phospholipase A2 isoforms (cPLA2α and cPLA2ε) in lipid mediator generation2022

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[Journal Article] Acrolein in cigarette smoke attenuates the innate immune responses mediated by surfactant protein D2020

Author(s)

Takamiya Rina 高宮里奈

TAKAMIYA Rina 高宮里奈