Moriguchi Shigeki 森口茂樹

… Alternative Names

MORIGUCHI Shigeki 森口茂樹

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Researcher Number	70374949
Other IDs
Affiliation (Current)	2025: 東北大学, 薬学研究科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 東北大学, 薬学研究科, 准教授 2016 – 2018: 東北大学, 薬学研究科, 講師 2015: 東北大学, 大学院薬学研究科, 講師 2012 – 2015: 東北大学, 薬学研究科(研究院), 講師 2009 – 2012: 東北大学, 大学院・薬学研究科, 講師 … More 2007 – 2009: Tohoku University, 大学院・薬学研究科, 助教 2006: 東北大学, 大学院薬学研究科, 助手 2005 – 2006: 東北大学, 大学院・薬学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Applied pharmacology / Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / Biological Sciences Except Principal Investigator Applied pharmacology / Biological pharmacy / Drug development chemistry / Biological Sciences
Keywords	Principal Investigator アルツハイマー病 / 認知機能 / CaMキナーゼII / CaMKII / KATPチャネル / 記憶学習 / PKC / NMDA受容体 / LTP / うつ症状 … More / メマンチン / whole-cell patch-clamp法 / CaM kinase II / 認知機能調節 / memantine / OBXマウス / OBX mice / ピロリドン誘導体 / nefiracetam / CaM Kinase II / 記憶学習機構 / 認知症 / 行動障害 / 新規MOA / 周辺症状 / 攻撃性行動 / ATP感受性カリウムチャネル / AD病態発症機序の解明 / アルツハイマー病周辺症状 / AD周辺症状 / ADの中核症状 / 遺伝子欠損マウス / 不安症状 / カルシウムシグナル / 扁桃体 / 不安様症状 / 中核・周辺症状 / 病態解明 / 精神機能障害 / 認知機能障害 / カルシウムイメージング法 / Kir6.2チャネル / 新規アダマンタン誘導体 / Memantine / 認知・精神機能 / AD脳糖尿病仮説 / KATPチャンネル / T型VGCC / 認知機能改善効果 / T-type VGCC / T-type CGCCs / ST101 / グリシン結合部位 / DM232 / 電気生理学 / NMDA受容体グリシン結合部位 / sunifiram / mGluR5 / α4β2型受容体 / galantamine / アルツハイマー / Alzheimer's disease / ニコチン性アセチルコリン受容体 / 電気生理学的解析 / 海馬 / BSRP / 行動逆耐性 / メタンフェタミン / LTD / シナプス可塑性 / 小胞体 / ジャンクトフィリン … More Except Principal Investigator CaMKII / T型カルシウムチャネル / アルツハイマー病 / 嗅球摘出マウス / 薬物治療学 / LTP / アセチルコリン / アミロイドβ / Ｔ型カルシウムチャネル / アラキドン酸 / 高次脳機能 / 情動行動異常 / ドパミンD2L受容体 / ドパミン神経 / 脂肪酸結合蛋白質 / 扁桃体 / CREB / H-FABP / ドパミン D2L 受容体 / 多価不飽和脂肪酸 / 統合失調症 / 薬理学 / カルモデュリン / eNOS / ジストロフィン / 心肥大 / バナジウム有機錯体 / 神経再生 / 血管再生 / 神経変性疾患 / 神経血管ユニット / アミロイド前駆タンパク質 / アルツハイマー病治療薬 / ST101 / 内皮型-酸化窒素合成酵素 / バナジウム化合物 / 認知機能 / 神経新生 / 脳血管保護作用 / 内皮型一酸化窒素合成酵素 / 脳血管障害 / キラルアダマンタン / アンタゴニスト / NMDA / イオンチャネル / グルタミン酸受容体 / アダマンタンアミノ酸 / アザアダマンタン / アダマンタンアミン / カルシウム / 情動行動 / 神経可塑性 / ドパミン / CaMキナーゼII Less

Elucidation of mechanism of dementia target for KATP channelPrincipal Investigator
- Principal Investigator
  
  森口茂樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Tohoku University
Elucidation of the behavioral and psychological symptoms of dementia target for KATP channelsPrincipal Investigator
- Principal Investigator
  
  Moriguchi Shigeki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Tohoku University
Mechanisms of both cognitive deficits and behavioral and psychological symptoms of Alzheimer's disease in KATP channel mutant micePrincipal Investigator
- Principal Investigator
  
  Moriguchi Shigeki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Tohoku University
Drug development of novel Kir6.2 channel inhibitor target for Alzheimer'ddiseasePrincipal Investigator
- Principal Investigator
  
  Moriguchi Shigeki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Functional significance of target molecule of cognitive enhancer ST101 and drug development
- Principal Investigator
  
  Fukunaga Kohji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Drug discovery study of Alzheimer's disease target for T-type calcium channel activationPrincipal Investigator
- Principal Investigator
  
  MORIGUCHI Shigeki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Drug development targeting for regeneration of neurovascular units in neurodegenerative disorders
- Principal Investigator
  
  FUKUNAGA Kohji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Role of fatty acid-binding protein in the brain vulnerability in schizophrenia
- Principal Investigator
  
  FUKUNAGA Kohji
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Development of Alzheimer's disease therapeutics mediate for enhancement of synaptic transmissionPrincipal Investigator
- Principal Investigator
  
  MORIGUCHI Shigeki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Effect of cognitive function mediated by NMDA receptor activation of new nootropic drug.Principal Investigator
- Principal Investigator
  
  MORIGUCHI Shigeki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Development of novel neuroprotective drugs targeting for neurovascular unit therapy.
- Principal Investigator
  
  FUKUNAGA Kohji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
小胞体機能異常による細胞内カルシウムシグナルと記憶学習の障害Principal Investigator
- Principal Investigator
  
  森口茂樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
NMDA受容体グリシン結合部位を標的とした新規アルツハイマー病治療薬の創薬研究Principal Investigator
- Principal Investigator
  
  森口茂樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
デルタ型CaMキナーゼIIの中枢ドパミン神経可塑性における役割
- Principal Investigator
  
  FUKUNAGA Kohji
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
アダマンタンアミン類の精密構造修飾に基づく高特異的イオンチャネルブロック薬の創製
- Principal Investigator
  
  IWABUCHI Yushiharu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Tohoku University

[Journal Article] Preventive effect of propolis on cognitive decline in Alzheimer’s disease model mice.2024
- Author(s)
  Ryo Inagaki, Tohru Yamakuni, Takashi Saito, Takaomi C Saido, Shigeki Moriguchi
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 139 Pages: 20-29
- DOI
  10.1016/j.neurobiolaging.2024.03.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06794, KAKENHI-PROJECT-21K15349, KAKENHI-PROJECT-23K26790
[Journal Article] Propolis promotes memantine-dependent rescue of cognitive deficits in APP-KI mice.2022
- Author(s)
  Shigeki Moriguchi, Ryo Inagaki, Takashi Saito, Takaomi C. Saido, Kohji Fukunaga.
- Journal Title
  
  Mol Neurobiol
  
  Volume: 59 Issue: 7 Pages: 4630-4646
- DOI
  10.1007/s12035-022-02876-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06794, KAKENHI-PROJECT-21K15349
[Journal Article] Memantine improves cognitive deficits via KATP channel inhibition in olfactory bulbectomized mice.2021
- Author(s)
  Shigeki Moriguchi, Ryo Inagaki, Kohji Fukunaga.
- Journal Title
  
  Mol Cell Neurosci
  
  Volume: 117 Pages: 103680-103680
- DOI
  10.1016/j.mcn.2021.103680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06794, KAKENHI-PROJECT-21K15349
[Journal Article] Kir6.1 heterozygous mice exhibit aberrant amygdala-dependent cued fear memory.2020
- Author(s)
  Ryo Inagaki, Shigeki Moriguchi and Kohji Fukunaga
- Journal Title
  
  Mol. Neurobiol.
  
  Volume: 57 Issue: 3 Pages: 1622-1635
- DOI
  10.1007/s12035-019-01840-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06887
[Journal Article] Memantine improves depressive-like behaviors via Kir6.1 channel inhibition in olfactory bulbectomized mice2020
- Author(s)
  Shigeki Moriguchi, Ryo Inagaki, Hirotsugu Shimojo, Yoshihiko Sugimura, Kohji Fukunaga
- Journal Title
  
  Neuroscience
  
  Volume: 442 Pages: 264-273
- DOI
  10.1016/j.neuroscience.2020.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06887
[Journal Article] Scabronine G Methyl Ester Improves Memory-Related Behavior and Enhances Hippocampal Cell Proliferation and Long-Term Potentiation via the BDNF-CREB Pathway in Olfactory Bulbectomized Mice2020
- Author(s)
  Nakagawasai Osamu、Lin Jia-Rong、Odaira Takayo、Takahashi Kohei、Nemoto Wataru、Moriguchi Shigeki、Yabuki Yasushi、Kobayakawa Yu、Fukunaga Kohji、Nakada Masahisa、Tan-No Koichi
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 11 Pages: 583291-583291
- DOI
  10.3389/fphar.2020.583291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06687, KAKENHI-PROJECT-18K06887, KAKENHI-PROJECT-19K23808
[Journal Article] Nicotine rescues depressive-like behaviors via α7-type nicotinic acetylcholine receptor activation in CaMKIV null mice2020
- Author(s)
  Shigeki Moriguchi, Ryo Inagaki, Lusha Yi, Mikako Shibata, Hiroyuki Sakagami, Kohji Fukunaga
- Journal Title
  
  Mol Neurobiol
  
  Volume: 57 Issue: 12 Pages: 4929-4940
- DOI
  10.1007/s12035-020-02077-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06887
[Journal Article] Aberrant Amygdala-Dependent Cued Fear Memory in Na+/Ca2+ Exchanger 1 Heterozygous Mice.2019
- Author(s)
  Moriguchi S, Kita S, Inagaki R, Yabuki Y, Sasaki Y, Ishikawa S, Sakagami H, Iwamoto T, Fukunaga K.
- Journal Title
  
  Mol Neurobiol
  
  Volume: 56 Issue: 6 Pages: 4381-4394
- DOI
  10.1007/s12035-018-1384-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08610, KAKENHI-PROJECT-18K06887, KAKENHI-PROJECT-19K07132
[Journal Article] Dysfunction of Na<sup>+</sup>/Ca<sup>2+</sup> exchangers is associated with cognitive decline in Alzheimer’s disease2018
- Author(s)
  Shigeki Moriguchi, Satomi Kita, Takahiro Iwamoto and Kohji Fukunaga
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 152 Issue: 6 Pages: 299-305
- DOI
  10.1254/fpj.152.299
- NAID
  130007528426
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06887
[Journal Article] Reduced expression of Na+/Ca2+ exchanges is associated with cognitive deficits seen in Alzheimer’s disease model mice.2018
- Author(s)
  Shigeki Moriguchi, Satomi Kita, Masahiro Fukaya, Makoto Osanai, Ryo Inagaki, Yuzuru Sasaki, Hisanao Izumi, Kyoji Horie, Junji Takeda, Takashi Saito, Hiroyuki Sakagami, Takaomi C Saido, Takahiro Iwamoto and Kohji Fukunaga
- Journal Title
  
  Neuropharmacology
  
  Volume: 131 Pages: 291-303
- Data Source
  KAKENHI-PROJECT-18K06887
[Journal Article] Reduced expression of Na+ /Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer's disease model mice2018
- Author(s)
  Moriguchi S, Kita S, Fukaya M, Osanai M, Inagaki R, Sasaki Y, Izumi H, Horie K, Takeda J, Saito T, Sakagami H, Saido TC, Iwamoto T, Fukunaga K
- Journal Title
  
  Neuropharmacology
  
  Volume: 131 Pages: 291-303
- DOI
  10.1016/j.neuropharm.2017.12.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08486, KAKENHI-PROJECT-16K08565, KAKENHI-PUBLICLY-17H05543, KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-17K08610
[Journal Article] Aberrant amygdala-dependent fear memory in corticosterone-treated mice.2018
- Author(s)
  Ryo Inagaki, Shigeki Moriguchi and Kohji Fukunaga
- Journal Title
  
  Neuroscience
  
  Volume: 388 Pages: 448-459
- DOI
  10.1016/j.neuroscience.2018.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06887, KAKENHI-PROJECT-16H05219
[Journal Article] Reduced CaM Kinase II and CaM Kinase IV Activities Underlie Cognitive Deficits in NCKX2 Heterozygous Mice.2018
- Author(s)
  Moriguchi S, Kita S, Yabuki Y, Inagaki R, Izumi H, Sasaki Y, Tagashira H, Horie K, Takeda J, Iwamoto T, Fukunaga K.
- Journal Title
  
  Mol Neurobiol.
  
  Volume: 55(5) Pages: 3889-3900
- DOI
  10.1007/s12035-017-0596-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08610, KAKENHI-PROJECT-16K19024, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-16K14574, KAKENHI-PROJECT-16K08565
[Journal Article] Stimulation of sigma-1 receptor ameliorates depressive-like behaviors via mitochondrial ATP production in CaMKIV null mice2016
- Author(s)
  Shigeki Moriguchi, Hiroyuki Sakagami, Yasushi Yabuki, Yuzuru Sasaki, Hisanao Izumi, Chen Zhang, Feng Han and Kohji Fukunaga
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 147 Issue: 4 Pages: 206-210
- DOI
  10.1254/fpj.147.206
- NAID
  130005143840
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K14574
[Journal Article] Functional Genomic Analyses Identify Pathways Dysregulated in Animal Model of Autism.2016
- Author(s)
  Huang JY, Tian Y, Wang HJ, Shen H, Wang H, Long S, Liao MH, Liu ZR, Wang ZM, Li D, Tao RR, Cui TT, Moriguchi S, Fukunaga K, Han F, Lu YM.
- Journal Title
  
  CNS Neurosci Ther.
  
  Volume: 22 Issue: 10 Pages: 845-853
- DOI
  10.1111/cns.12582
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-16K14574
[Journal Article] Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy.2016
- Author(s)
  Moriguchi S, Ishizuka T, Yabuki Y, Shioda N, Sasaki Y, Tagashira H, Yawo H, Yeh JZ, Sakagami H, Narahashi T, Fukunaga K.
- Journal Title
  
  Mol Psychiatry.
  
  Volume: 印刷中 Issue: 2 Pages: 211-221
- DOI
  10.1038/mp.2016.187
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01413, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-15K15025, KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-16K14574, KAKENHI-PROJECT-16K19024, KAKENHI-PROJECT-16K08265, KAKENHI-PROJECT-25250001
[Journal Article] The extracellular fragment of GPNMB improves memory and increases hippocampal GluA1 levels in mice.2015
- Author(s)
  Murata K., Yoshino Y., Tsuruma K., Moriguchi S., Oyagi A., Tanaka H., Ishisaka M., Shimazawa M., Fukunaga K., Hara H.
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 132 Issue: 5 Pages: 583-594
- DOI
  10.1111/jnc.13010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J09790, KAKENHI-PROJECT-15K08583
[Journal Article] Behavioral Sensitization by Methamphetamine in Junctophilin-Deficient Mice2015
- Author(s)
  Moriguchi S, Nishi M, Sasaki Y, Takeshima H, Fukunaga K
- Journal Title
  
  Mol Neurobiol
  
  Volume: 51 Issue: 2 Pages: 533-542
- DOI
  10.1007/s12035-014-8737-2
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
[Journal Article] Stimulation of Sigma-1 Receptor Ameliorates Depressive-like Behaviors in CaMKIV Null Mice.2015
- Author(s)
  Moriguchi, S.;Sakagami, H.;Yabuki, Y.;Sasaki, Y.;Izumi, H.;Zhang, C.;Han, F.;Fukunaga, K.
- Journal Title
  
  Mol Neurobiol
  
  Volume: 52 Issue: 3 Pages: 1210-1222
- DOI
  10.1007/s12035-014-8923-2
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-25293124
[Journal Article] CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment.2014
- Author(s)
  Shigeki Moriguchi
- Journal Title
  
  J Neurochem.
  
  Volume: 128(6) Issue: 6 Pages: 927-937
- DOI
  10.1111/jnc.12510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J04360, KAKENHI-PROJECT-22300114, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25640025
[Journal Article] Rivastigmine improves hippocampal neurogenesis and depressive-like behaviors via 5-HT1A receptor stimulation in olfactory bulbectomized mice.2014
- Author(s)
  Muhammad Rashedul Islam, Shigeki Moriguchi, Hideaki Tagashira and Kohji Fukunaga
- Journal Title
  
  Neuroscience
  
  Volume: 272 Pages: 116-130
- DOI
  10.1016/j.neuroscience.2014.04.046
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
[Journal Article] Rivastigmine restores 5-HT1A receptor levels in the hippocampus of olfactory bulbectomized mice.2014
- Author(s)
  Muhammad Rashedul Islam, Shigeki Moriguchi, Hideaki Tagashira and Kohji Fukunaga
- Journal Title
  
  Advances in Alzheimer’s disease
  
  Volume: 3 Issue: 03 Pages: 128-136
- DOI
  10.4236/aad.2014.33012
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
[Journal Article] Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism2014
- Author(s)
  Tian Y, Yabuki Y, Moriguchi S, Fukunaga K, Mao PJ, Hong LJ, Lu YM, Wang R, Ahmed MM, Liao MH, Huang JY, Zhang RT, Zhou TY, Long S, Han F
- Journal Title
  
  J Pineal Res.
  
  Volume: 56 Issue: 1 Pages: 1-11
- DOI
  10.1111/jpi.12081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
[Journal Article] A novel cognitive enhancer, ST101, enhances acetylcholine release in mouse dorsal hippocampus through T-type voltage-gated calcium channel stimulation2013
- Author(s)
  Yui Yamamoto, Norifumi Shioda, Feng Han, Shigeki Moriguchi and Kohji Fukunaga
- Journal Title
  
  J. Pharmacol. Sci.
  
  Volume: 121 Pages: 212-226
- NAID
  10031165466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590653
[Journal Article] Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice.2013
- Author(s)
  Shigeki Moriguchi, Yasuharu Shinoda, Yui Yamamoto, Yuzuru Sasaki, Kosuke Miyajima, Hideaki Tagashira and Kohji Fukunaga
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 1
- DOI
  10.1371/annotation/9fdc3705-7112-4382-a3a2-dcde33229272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590653
[Journal Article] Novel nootropic drug sunifiram enhances hippocampal synaptic efficact via glycine-binding site of N-methyl-D-aspartate receptor2013
- Author(s)
  Moriguchi S, Tanaka T, Narahashi T, Fukunaga K
- Journal Title
  
  Hippocampus
  
  Volume: 23 Pages: 942-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293124
[Journal Article] The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation.2013
- Author(s)
  Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 121(3) Pages: 212-226
- NAID
  10031165466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation2013
- Author(s)
  Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 121 Issue: 3 Pages: 212-226
- DOI
  10.1254/jphs.12233FP
- NAID
  10031165466
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293124
[Journal Article] Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-asparatate receptor2013
- Author(s)
  Moriguchi S, Tanaka T, Narahashi T, Fukunaga K
- Journal Title
  
  Hippocampus
  
  Volume: 23 Issue: 10 Pages: 942-51
- DOI
  10.1002/hipo.22150
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
[Journal Article] Stimulation of the Sigma-1 Receptor by DHEA Enhances Synaptic Effic acy and Neurogenesis in the Hippocampal Dentate Gyrus of Olfactory Bulbectomized Mice.2013
- Author(s)
  Shigeki Moriguchi
- Journal Title
  
  PLoS One.
  
  Volume: 8(4) Issue: 4 Pages: e60863-e60863
- DOI
  10.1371/journal.pone.0060863
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04360, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-24890144, KAKENHI-PROJECT-25293124
[Journal Article] Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice.2013
- Author(s)
  Moriguchi S, Tanaka T, Tagashira H, Narahashi T, Fukunaga K.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 242 Pages: 150-157
- DOI
  10.1016/j.bbr.2012.12.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-24102505
[Journal Article] Decreased CaMKII and PKC activities in specific brain regions are associated with cognitive impairment in neonatal ventral hippocampus-lesioned rats.2013
- Author(s)
  Yabuki Y, Nakagawasai O, Moriguchi S, Shioda N, Onogi H, Tan-No K, Tadano T, Fukunaga K.
- Journal Title
  
  Neuroscience
  
  Volume: 234 Pages: 103-115
- DOI
  10.1016/j.neuroscience.2012.12.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790072, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PUBLICLY-25110705, KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25460090, KAKENHI-PUBLICLY-23110501
[Journal Article] The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101 : enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices2012
- Author(s)
  Moriguchi S, Shioda N, Yamamoto Y, Tagashira H, Fukunaga K
- Journal Title
  
  J Neurochem.
  
  Volume: 121 Pages: 44-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Aberrant hippocampal spine morphology and impaired memory formation in neuronal platelet-derived growth factor beta-receptor lacking mice.2012
- Author(s)
  Shioda N, Moriguchi S, Oya T, Ishii T, Shen J, Matsushima T, Nishijo H, Sasahara M, Fukunaga K.
- Journal Title
  
  Hippocampus
  
  Volume: 22(6) Issue: 6 Pages: 1371-1378
- DOI
  10.1002/hipo.20973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240051, KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-22659012, KAKENHI-PUBLICLY-23110501, KAKENHI-PROJECT-23300147, KAKENHI-PROJECT-23590444, KAKENHI-PROJECT-23790072, KAKENHI-PROJECT-24590653
[Journal Article] Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice2012
- Author(s)
  Moriguchi S, Yabuki Y, Fukunaga K
- Journal Title
  
  J Neurochem
  
  Volume: 120(4) Issue: 4 Pages: 541-51
- DOI
  10.1111/j.1471-4159.2011.07608.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24590653
[Journal Article] Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice2012
- Author(s)
  Moriguchi S, Yabuki Y, Fukunaga K
- Journal Title
  
  J.Neurochem.
  
  Volume: 120 Pages: 541-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101 : enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices2012
- Author(s)
  Moriguchi S, Shioda N, Yamamoto Y, Tagashira H, Fukunaga K
- Journal Title
  
  J Neurochem
  
  Volume: 121 Pages: 44-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Reduced caicium/calmodulin-dependent protein kiaase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice2012
- Author(s)
  Moriguchi S, Yabuki Y, Fukunaga K
- Journal Title
  
  J.Neurochem.
  
  Volume: 120 Pages: 541-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101 : Enhancement of long-term potentiation and CaMKll autophosphorylation in rat cortical slices.2012
- Author(s)
  Shigeki Moriguchi
- Journal Title
  
  J Neurochem.
  
  Volume: 121(1) Issue: 1 Pages: 44-53
- DOI
  10.1111/j.1471-4159.2012.07667.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04360, KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-23790072, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PUBLICLY-23110501, KAKENHI-PUBLICLY-24102505
[Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011
- Author(s)
  Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H.
- Journal Title
  
  Brain Res
  
  Volume: 1419 Pages: 97-104
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21945083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardio protection.2011
- Author(s)
  Moriguchi S, Oomura Y, ShiodaN, Han F, Hori N, Aou S, Fukunaga K
- Journal Title
  
  Mol Cell Neurosci.
  
  Volume: 46 Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Ca(2+)/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011
- Author(s)
  Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K
- Journal Title
  
  Mol.Cell Neurosci.
  
  Volume: 46 Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011
- Author(s)
  Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H
- Journal Title
  
  Brain Res
  
  Volume: 1419 Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Roles of PDGF receptor-beta in the structure and function of postnatal kidney glomerulus.Nephrol.2011
- Author(s)
  Nogami T.
- Journal Title
  
  Hippocampus
  
  Volume: 21 Issue: 6 Pages: 678-687
- DOI
  10.1002/hipo.20782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390108, KAKENHI-PROJECT-22659012
[Journal Article] Prandial increases of leptin and orexin in the brain modulate spatial learning and memory2011
- Author(s)
  Yutaka Oomura, Shuji Aou, Kohji Fukunaga, Shigeki Moriguchi and Kazuo Sasaki
- Journal Title
  
  Neurosci. Behav. Physiol
  
  Volume: 41 Pages: 233-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior.2011
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  Yakugaku Zasshi.
  
  Volume: 131 Pages: 505-511
- NAID
  130000678830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011
- Author(s)
  Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K
- Journal Title
  
  J.Neurochem.
  
  Volume: 117 Pages: 879-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Ca2+/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011
- Author(s)
  Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K.
- Journal Title
  
  Mol Cell Neurosci
  
  Volume: 46(1) Pages: 101-7
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20807573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011
- Author(s)
  Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K
- Journal Title
  
  J.Neurochem.
  
  Volume: 117 Pages: 879-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Pharmacological study on Alzheimer's drugs targeting for calcium/calmodulin-dependent protein kinase II2011
- Author(s)
  Moriguchi S
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 117 Pages: 6-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011
- Author(s)
  Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H
- Journal Title
  
  Brain Res.
  
  Volume: 24 Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior2011
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  Yakugaku Zasshi.
  
  Volume: 131 Pages: 505-511
- NAID
  130000678830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice.2011
- Author(s)
  Nogami T, Beppu H, Tokoro T Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sa Sahara M, Shimada Y, NishijoH, Li E, Kitajima I
- Journal Title
  
  Hippocampus.
  
  Volume: 印刷中(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Ca^<2+>/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011
- Author(s)
  Shigeki Moriguchi, Yutaka Oomura, Norifumi Shioda, Feng Han, Nobuaki Hori, Shuji Aou, Kohji Fukunaga
- Journal Title
  
  Mol.Cell.Neurosci.
  
  Volume: 46 Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Pharmacological study on Alzheimer's drugs targeting for calcium/calmodulin-dependent protein kinase II2011
- Author(s)
  Shigeki Moriguchi
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 117 Pages: 6-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011
- Author(s)
  Shigeki Moriguchi, Yui Yamamoto, Tatsuya Ikuno, Kohji Fukunaga
- Journal Title
  
  J.Neurochem.
  
  Volume: 117 Pages: 879-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011
- Author(s)
  Atsushi Oyagi, Shigeki Moriguchi, Atsumi Nitta, Kenta Murata, Yasuhisa Oida, Kazuhiro Tsuruma, Masamitsu Shimazawa, Kohji Fukunaga and Hideaki Hara
- Journal Title
  
  Brain Res
  
  Volume: 1419 Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Ca^<2+>/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011
- Author(s)
  Shigeki Moriguchi, Yutaka Oomura, Norifumi Shioda, Feng Han, Nobuaki Hori, Shuji Aou and Kohji Fukunaga
- Journal Title
  
  Mol. Cell. Neurosci
  
  Volume: 46 Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardio protection.2011
- Author(s)
  Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K
- Journal Title
  
  Mol Cell Neurosci.
  
  Volume: 46 Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice2011
- Author(s)
  Nogami T, Beppu H, Tokoro T, Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sasahara M, Shimada Y, Nishijo H, Li E, Kitajima I
- Journal Title
  
  Hippocampus
  
  Volume: 21 Pages: 678-687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Prandial increases of leptin and orexin in the brain modulate spatial learning and memory2011
- Author(s)
  Yutaka Oomura, Shuji Aou, Kohji Fukunaga, Shigeki Moriguchi, Kazuo Sasaki
- Journal Title
  
  Neurosci.Behav.Physiol.
  
  Volume: 41 Pages: 233-242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011
- Author(s)
  Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H
- Journal Title
  
  Brain Res.
  
  Volume: 24 Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice.2011
- Author(s)
  Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K.
- Journal Title
  
  J Neurochem.
  
  Volume: 印刷中(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Ca(2+)/calinodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011
- Author(s)
  Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K
- Journal Title
  
  Mol.Cell Neurosci.
  
  Volume: 46 Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior.2011
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  Yakugaku Zasshi.
  
  Volume: 131 Pages: 505-511
- NAID
  130000678830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Ca(2+)/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011
- Author(s)
  Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K
- Journal Title
  
  Mol Cell Neurosci
  
  Volume: 46 Pages: 101-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor2011
- Author(s)
  Tatsuya Nogami, Hideyuki Beppu, Takashi Tokoro, Shigeki Moriguchi, Norifumi Shioda, Kohji Fukunaga, Toshihisa Ohtsuka, Yoko Ishii, Masakiyo Sasahara, Yutaka Shimada, Hisao Nishijo, En Li and Isao Kitajima
- Journal Title
  
  causes hippocampal dysfunction in mice
  
  Volume: 21 Pages: 678-687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior2011
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 131 Pages: 505-511
- NAID
  130000678830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior2011
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K.
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 131(4) Pages: 505-11
- NAID
  130000678830
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21467789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice2011
- Author(s)
  Tatsuya Nogami, Hideyuki Beppu, Takashi Tokoro, Shigeki Moriguchi, Norifumi Shioda, Kohji Fukunaga, Toshihisa Ohtsuka, Yoko Ishii, Masakiyo Sasahara, Yutaka Shimada, Hisao Nishijo, En Li, Isao Kitajima
- Journal Title
  
  Hippocampus
  
  Volume: 21 Pages: 678-687
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Pharmacological study on Alzheimer's drugs targeting for calcium/calmodulin-dependent protein kinase II2011
- Author(s)
  Shigeki Moriguchi
- Journal Title
  
  J.Pharmacol.Sci.
  
  Volume: 117 Pages: 6-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011
- Author(s)
  Shigeki Moriguchi, Yui Yamamoto, Tatsuya Ikuno and Kohji Fukunaga
- Journal Title
  
  J. Neurochem
  
  Volume: 117 Pages: 879-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011
- Author(s)
  Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K
- Journal Title
  
  J Neurochem
  
  Volume: 117(5) Issue: 5 Pages: 879-91
- DOI
  10.1111/j.1471-4159.2011.07256.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-22659012
[Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior2011
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 131 Pages: 505-511
- NAID
  130000678830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice.2011
- Author(s)
  Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K.
- Journal Title
  
  J Neurochem.
  
  Volume: (未定)(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] A novel cognitive enhancer, ZSET1446/ST101, promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice2010
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Yamaguchi Y, Hino M, Fukunaga K.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 333(1) Pages: 43-50
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/2006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] A novel cognitive enhancer, spino[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446/ST101), promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice.2010
- Author(s)
  Norifumu Shioda, Yui Yamamoto, Feng Han, Shigeki Moriguchi, Yoshimasa Yamaguchi, Masataka Hino, Kohji Fukunaga
- Journal Title
  
  J.Pharmacol.Exp.Ther.
  
  Volume: 333 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice.2010
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Yamaguchi Y, Hino M, Fukunaga K
- Journal Title
  
  J.Pharmacol.Exp.Ther.
  
  Volume: 333 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] [Donepezil-induced neuroprotection of acetylcholinergic neurons in olfactory bulbectomized mice]2010
- Author(s)
  Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  Yakugaku Zasshi.
  
  Volume: 130 Pages: 717-721
- NAID
  130000259461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Donepezil-induced neuroprotection of acetykholinergic neurons in olfactory bulbectomized mice2010
- Author(s)
  Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  Yakugaku Zasshi.
  
  Volume: 130 Pages: 717-721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Donepezil-induced neuroprotection of acetylcholinergic neurons in olfactory bulbectomized mice2010
- Author(s)
  Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K.
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 130(5) Pages: 717-21
- NAID
  130000259461
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20460870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Donepezil-induced neuroprotection of acetylcholinergic neurons in olfactory bulbectomized mice2010
- Author(s)
  Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 130 Pages: 717-721
- NAID
  130000259461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST10I, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice.2010
- Author(s)
  Shioda N, Yamamoto Y, Ban F, Moriguchi S, Yamaguchi Y, Hino M, Fukunaga K
- Journal Title
  
  J.Pharmacol.Exp.Ther.
  
  Volume: 333 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Platelet-activating factor-induced synaptic facilitation is associated with increased calcium/calrnodulin-dependent protein kinase II, protein kinase C and extracellular signal-regulated kinase activities in the rat hippocampal CAl region.2010
- Author(s)
  Moriguchi S, Shioda N, Yamamoto Y, Fukunaga K
- Journal Title
  
  Neuroscience.
  
  Volume: 166 Pages: 1158-1166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Platelet-activating factor-induced synaptic facilitation is associated with increased calcium/calmodulin-dependent protein kinase II, protein kinase C and extracellular signal-regulated kinase activities in the rat hip pocampal CA1 region.2010
- Author(s)
  Moriguchi S, Shioda N, Yamamoto Y, Fukunaga K
- Journal Title
  
  Neuroscience.
  
  Volume: 166 Pages: 1158-1166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Essential role of meuron-enriched diacylglycerol kinase (DGK), DGKβ in neurite spine formation, contributing to cognitive function.2010
- Author(s)
  Yasuhito Shirai, Takeshi Kouzuki, Kenichi Kakefuda, Shigeki Moriguchi, Atsushi Oyagi, Kyoji Horie, Shin-ya Morita, Masamitsu Shimazawa, Kohji Fukunaga, Junji Kakeda, Naoaki Saito, Hideaki Hara
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790509
[Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice2010
- Author(s)
  Shioda N, Yamamoto Y, Han F, Moriguchi S, Yamaguchi Y, Hino M, Fukunaga K
- Journal Title
  
  J. Pharmacol. Exp. Ther
  
  Volume: 333 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice2010
- Author(s)
  N. Shioda, Y. Yamamoto, F. Han, S. Moriguchi, Y. Yamaguchi, M. Hino, K. Fukunaga
- Journal Title
  
  J.Pharmacol.Exp.Ther. 333
  
  Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKbeta in neurite spine formation, contributing to cognitive function2010
- Author(s)
  Shirai Y, Kouzuki T, Kakefuda K, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, Saito N, Hara H
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKbeta in neurite spine formation, contributing to cognitive function2010
- Author(s)
  Shirai Y, Kouzuki T, Kakefuda K, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, Saito N, Hara H.
- Journal Title
  
  PLoS One
  
  Volume: 5(7)
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20657643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Essential role of neuron-enriched diacylglycerol kinase(DGK), DGKbeta in neurite spine formation, contributing to cognitive function.2010
- Author(s)
  Shirai Y, Kouzuki T, KakefudaK, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, SaitoN, Hara H
- Journal Title
  
  PLoS One.
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659012
[Journal Article] Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKb eta in neurite spine formation, contributing to cognitive function.2010
- Author(s)
  Shirai Y, Kouzuki T, Kakefuda K, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, Saito N, Hara H
- Journal Title
  
  PLoS One.
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor causes hippocampal dysfunction in mice.2010
- Author(s)
  Nogami T, Beppu H, Tokoro T, Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sasahara M, Shimada Y, Nishijo H, Li E, Kitajima I
- Journal Title
  
  Hippocampus.
  
  Volume: (未定)(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390109
[Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice.2010
- Author(s)
  N.Shioda, Y.Yamamoto, F.Han, S.Moriguchi, Y.Yamaguchi, M.Hino, K.Fukunaga
- Journal Title
  
  J.Pharmacol.Exp.Ther. 333
  
  Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyllethyl]-5, 6-dimethoxyindazole (DY-9836), a novel calmodulin antagonist2009
- Author(s)
  Lu Ym, Han F, Shioda N, Moriguchi S, Shirasaki Y, Qin ZH, Fukunaga K.
- Journal Title
  
  Mol Pharmacol. 75
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nefiracetam and galantamine modulation of excitatory and inhibitory synaptic transmission via stimulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons.2009
- Author(s)
  Shigeki Moriguchi, Xilong Zhao, William Marszalec, Jay Z Yeh, Kohji Fukunaga, Toshio Narahashi
- Journal Title
  
  Neuroscience 160
  
  Pages: 484-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Prandial increases of leptin and orexin in the brain modulate spatial learning and memory2009
- Author(s)
  Yutaka Oomura, Shuji Aou, Kohji Fukunaga, Shigeki Moriguchi, Kazuo Sasaki
- Journal Title
  
  Russian Journal of Physiology 95
  
  Pages: 1373-1385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Generation and characterization of conditional heparin-binding EGF-like growth factor knockout mice2009
- Author(s)
  Atsushi Oyagi, Yasuhisa Oida, Kenichi Kakefuda, Masamitsu Shimazawa, Norifumi Shioda, Shigeki Moriguchi, Kiyoyuki Kitaichi, Daisuke Nanba, Kazumasa Yamaguchi, Yasuhide Furuta, Kohji Fukunaga, Shigeki Higashiyama, Hideaki Hara
- Journal Title
  
  PLoS one 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Prandial increases of leptin and orexin in the brain modulate spatial learning and memory.2009
- Author(s)
  Y.Oomura, S.Aou, K.Fukunaga, S.Moriguchi, K.Sasaki
- Journal Title
  
  Ross.Fiziol.Zh.Im.I.M.Sechenova 95
  
  Pages: 1373-1385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazole(DY-9836), a novel calmodulin antagonist.2009
- Author(s)
  M.Lu, F.Han, N.Shioda, S.Moriguchi. Y.Shirasaki, ZH.Qin, K.Fukunaga
- Journal Title
  
  Mol.Pharmacol. 75
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation.2009
- Author(s)
  Yui Yamamoto, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Akira Nakajima, Akihito Yokosuka, Yoshihiro Mimaki, Yutaka Sashida, Tohru Yamakuni, Yasushi Ohizumi, Kohji Fukunaga
- Journal Title
  
  Brain Res. 1295
  
  Pages: 218-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation2009
- Author(s)
  Shigeki Moriguchi, Norifumi Shioda, Feng Han, Jay Z Yeh, Toshio Narahashi, Kohji Fukunaga
- Journal Title
  
  Hippocampus 19
  
  Pages: 844-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation.2009
- Author(s)
  S.Moriguchi, N.Shioda, F.Han, JZ.Yeh, T.Narahashi, K.Fukunaga
- Journal Title
  
  Hippocampus 19
  
  Pages: 844-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nefiracetam and galantamine modulation of excitatory and inhibitory synaptic transmission via stimulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons2009
- Author(s)
  Shigeki Moriguchi, Xilong Zhao, William Marszalec, Jay Z Yeh, Kohji Fukunaga, Toshio Narahashi
- Journal Title
  
  Neuroscience 160
  
  Pages: 484-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Nefiracetain and Galantamine Modulation of Excitatory and Inhibitory Synaptic Transmission via Stimulation of Neuronal Nicotinic Acetylcholine Recentors in Rat Cortical Neurons2009
- Author(s)
  Moriguchi S, Zhao X, Marszalec W, Yeh JZ, Fukunaga K, Narahashi T.
- Journal Title
  
  Neuroscience. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nefiracetam and galantamine modulation of excitatory and inhibitory synaptic transmission via stimulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons.2009
- Author(s)
  S.Moriguchi, X.Zhao, W.Marszalec, JZ.Yeh, K.Fukunaga, T.Narahashi
- Journal Title
  
  Neuroscience 160
  
  Pages: 484-491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice.2009
- Author(s)
  S.Moriguchi, F.Han, N.Shioda, Y.Yamamoto, T.Nakajima, O.Nakagawasai, T.Tadano, JZ.Yeh, T.Narahashi, K.Fukunaga
- Journal Title
  
  J.Neurochem. 110
  
  Pages: 170-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nefiracetam activation of CaM kinase II and Protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice.2009
- Author(s)
  Shigeki Moriguchi, Feng Han, Norifumi Shioda, Yui Yamamoto, Takeharu Nakajima, Osamu Nakagawasai, Takeshi Tadano, Jay Z Yeh, Toshio Narahashi, Kohji Fukunaga
- Journal Title
  
  J. Neurochem. 110
  
  Pages: 170-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Galantamine enhancement of long-term potentiation is mediated by calcium / calmodulin-dependent protein kinase II and protein kinase C activation2009
- Author(s)
  Moriguchi S, Shioda N, Han F, Yeh JZ, Narahashi T, Fukunaga K.
- Journal Title
  
  Hippocampus. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation.2009
- Author(s)
  Y.Yamamoto, N.Shioda, F.Han, S.Moriguchi, A.Yokosuka, Y.Mimaki, Y.Sashida, T.Yamakuni, Y.Ohizumi, K.Fukunaga
- Journal Title
  
  Brain Res. 1295
  
  Pages: 218-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazol e (DY-9836), a novel calmodulin antagonist2009
- Author(s)
  YM. Lu, F. Han, N. Shioda, S. Moriguchi. Y. Shirasaki, ZH. Qin, K. Fukunaga
- Journal Title
  
  Mol.Pharmacol. 75
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nefiracetam activation of CaM kinase II and Protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice2009
- Author(s)
  Shigeki Moriguchi, Feng Han, Norifumi Shioda, Yui Yamamoto, Takeharu Nakajima, Osamu Nakagawasai, Takeshi Tadano, Jay Z Yeh, Toshio Narahashi, Kohji Fukunaga
- Journal Title
  
  Journal of Neurochemistry 110
  
  Pages: 170-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazole (DY9836), a novel calmodulin antagonist2009
- Author(s)
  Ying-Mei Lu, Fang Han, Norifumi Shioda, Shigeki Moriguchi, Yasufumi Shirasaki, Zheng-Hong Qin, Kohji Fukunaga
- Journal Title
  
  Molecular Pharmacology 75
  
  Pages: 101-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation2009
- Author(s)
  Yui Yamamoto, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Akira Nakajima, Akihito Yokosuka, Yoshihiro Mimaki, Yutaka Sashida, Tohru Yamakuni, Yasushi Ohizumi, Kohji Fukunaga
- Journal Title
  
  Brain Research 1295
  
  Pages: 218-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Generation and Characterization of Conditional Heparin-Binding EGF-Like Growth Factor Knockout Mice.2009
- Author(s)
  A.Oyagi, Y.Oida, K.Kakefuda, M.Shimazawa, N.Shioda, S.Moriguchi, K.Kitaichi, D.Nanba, K.Yamaguchi, Y.Furuta, K.Fukunaga, S.Higashiyama, H.Hara
- Journal Title
  
  PLoS ONE 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation.2009
- Author(s)
  Shigeki Moriguchi, Norifumi Shioda, Feng Han, Jay Z Yeh, Toshio Narahashi, Kohji Fukunaga
- Journal Title
  
  Hippocampus 19
  
  Pages: 844-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism.2008
- Author(s)
  F. Han, N. Shioda, S. Moriguchi, Z. H. Qin, K. Fukunaga.
- Journal Title
  
  Neurosci Lett. 430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Cardioprotective effect of vanadyl sulfate on ischemia / reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein2008
- Author(s)
  Bhuiyan MS, Takada Y, Shioda N, Moriguchi S, Kasahara J. Fukunaga K.
- Journal Title
  
  Cardidvasc Ther. 26
  
  Pages: 10-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism.2008
- Author(s)
  Feng Han, Norifumi Shioda, Shigeki Moriguchi, Zheng-Hong Qin, Kohji Fukunaga
- Journal Title
  
  Neurosci. Lett. 430
  
  Pages: 275-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Nobiletin, a citrus flavonoid with neurotrophic action, augments prote in kinase A-mediated phosphorylation of the AMPA receptor subunit, Glu R1, and the postsynaptic receptor response to glutamate in murine hippocampus.2008
- Author(s)
  K. Matsuzaki, K. Miyazaki, S. Sakai, H. Yawo, N. Nakata, S. Moriguchi, K. Fukunaga, A. Yokosuka, Y. Sashida, Y. Mimaki, T. Yamakuni, Y. Ohizumi.
- Journal Title
  
  Eur J Pharmacol. 578
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus.2008
- Author(s)
  Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizumi
- Journal Title
  
  Eur. J. Pharmacol. 578
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Cardioprotective effect of vanadyl sulfate on ischemia/reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein2008
- Author(s)
  MS. Bhuiyan, Y. Takada, N. Shioda, S. Moriguchi, J. Kasahara, K. Fukunaga
- Journal Title
  
  Cardiovasc.Ther. 26
  
  Pages: 10-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Cytoprotective effect of bis(1-oxy-2-pyridinethiolato)oxovanadiun(IV) on myocardial ischemia/reperfusion injury elicits inhibition of Fas ligand and Bim expression and elevation of FLIP expression2008
- Author(s)
  MS. Bhuiyan, M. Shibuya, N. Shioda, S. Moriguchi, J. Kasahara, Y. Iwabuchi, K. Fukunaga
- Journal Title
  
  Eur.J.Pharmacol. 571
  
  Pages: 180-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocameal CAI region2008
- Author(s)
  Moriguchi S, Shioda N, Han F, Narahashi T, Fukunaga K.
- Journal Title
  
  J Neurochem. 106
  
  Pages: 1092-1103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism2008
- Author(s)
  F. Han, N. Shioda, S. Moriguchi, ZH. Qin, K. Fukunaga
- Journal Title
  
  Neurosci.Lett. 430
  
  Pages: 275-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] ZSET1446(ST101)treatment rescues olfactory bulbectomy-induced memory impairment by activating CaM kinase II and protein kinase C in mouse hippocampus.2008
- Author(s)
  F. Han, N, Shioda, S. Moriguchi, Y .Yamamoto, A.A. Raie, Y. Yamaguchi, M. Hino, K. Fukunaga.
- Journal Title
  
  J Pharmacol Exp Ther. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocampal CA1 region.2008
- Author(s)
  Shigeki Moriguchi, Norifumi Shioda, Feng Han, Toshio Narahashi, Kohji Fukunaga
- Journal Title
  
  J. Neurochem. 106
  
  Pages: 1092-1103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446/ST101) treatment rescues olfactory bulbectomy-induced memory impairment by activating Ca2+/calmodulin kinase II and protein kinase C in mouse hippocampus2008
- Author(s)
  F. Han, N. Shioda, S. Moriguchi, Y. Yamamoto, AY. Raie, Y. Yamaguchi, M. Hino, K. Fukunaga
- Journal Title
  
  J.Pharmacol.Exp.Ther. 326
  
  Pages: 127-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Spino[imidazo[1, 2-a]pyridine-3, 2-indan]-2(3H)-one (ZSET1446/ST101) treatment rescues olfactory bulbectomy-induced memory impairment by activating CaM kinase II and protein kinase C in mouse hippocampus.2008
- Author(s)
  Feng Han, Norifumi Shioda, Shigeki Moriguchi, Yui Yamamoto, Alisar Ali Raie, Yoshimasa Yamaguchi, Masataka Hino, Kohji Fukunaga
- Journal Title
  
  J. Pharmacol. Exp. Ther. 326
  
  Pages: 127-134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] The vanadium (IV) compound rescues septo-hippocampal cholinergic neurons from neurodegeneration in olfactory bulbectomized mice2008
- Author(s)
  Feng Han, Norifumi Shioda, Shigeki Moriguchi, Zheng-Hong Qin and Kohji Fukunaga
- Journal Title
  
  Neuroscience 151
  
  Pages: 671-679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] The vanadium (IV) compound rescues septo-hippocampal cholinergic neurons from neurodegeneration in olfactory bulbectomized mice2008
- Author(s)
  F. Han, N. Shioda, S. Moriguchi, ZH. Qin, K. Fukunaga
- Journal Title
  
  Neuroscience 151
  
  Pages: 671-679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] The vanadium (IV) compound rescues septo-hippocampal cholinergic neurons from neurodegeneration in olfactory bulbectomized mice.2008
- Author(s)
  Feng Han, Norifumi Shioda, Shigeki Moriguchi, Zheng-Hong Qin, Kohji Fukunaga
- Journal Title
  
  Neuroscience 151
  
  Pages: 671-679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790398
[Journal Article] Imbalance between CaM kinase II and calcineurin activities imparis caffeine-induced calcium relase in hypertrophic cardiomyoc2007
- Author(s)
  Ying-Mei Lu, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Jiro Kasahara, Yasufumi Shirasaki, Zheng-Hong Qin and Kohji Fukunaga
- Journal Title
  
  Biochemical Pharmacology 74
  
  Pages: 1727-1737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18059003
[Journal Article] Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia2007
- Author(s)
  N. Shioda, F. Han, S. Moriguchi, K. Fukunaga
- Journal Title
  
  J.Neurochem. 102
  
  Pages: 1506-1517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional a ctivities in mouse brain ischemia.2007
- Author(s)
  Norifumi Shioda, Feng Han, Shigeki Moriguchi and Kohji Fukunaga
- Journal Title
  
  Journal of Neurochemistry 102
  
  Pages: 1506-1517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18059003
[Journal Article] Nefiracetam potentiates NMDA receptor function via PKC activation and reduces magnesium block of NMDA receptor.2007
- Author(s)
  S. Moriguchi, N. Shioda, H. Maejima, X. Zhao, W. Marszalec, J. Z. Yeh, K. Fukunaga and T. Narahashi
- Journal Title
  
  Molecular Pharmacology 71
  
  Pages: 580-587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Activation of PI3K/Akt pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia.2007
- Author(s)
  N. Shioda, T. Ishigami, F. Han, S. Moriguchi, M. Shibuya, Y. Iwabuchi and K. Fukunaga
- Journal Title
  
  Neuroscience 148
  
  Pages: 221-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nefiracetam potentiates NMDA receptor function via PKC activation and reduces magnesium block of NMDA receptor.2007
- Author(s)
  Shigeki Moriguchi, Norifumi Shioda, Hiroshi Maejima, Xilong Zhao, William Marszalec, Jay Z. Yeh, Kohji Fukunaga and Toshio Narahashi
- Journal Title
  
  Molecular Pharmacology 71
  
  Pages: 580-587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18059003
[Journal Article] Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia2007
- Author(s)
  N. Shioda, T. Ishigami, F. Han, S. Moriguchi, M. Shibuya, Y. Iwabuchi, K. Fukunaga
- Journal Title
  
  Neuroscience 148
  
  Pages: 221-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Cytoprotective effect of bis(1-oxy-2-pyridinethiolato)oxovanadiun(IV)on myocardial ischemia/reperfusion injury elicits inhibition of Fas li gand end Bim expression and elevation of FLIP expression.2007
- Author(s)
  M. S. Bhuiyan, M. Shibuya, N. Shioda, S. Moriguchi, J. Kasahara, Y. Iwabuchi and K. Fukunaga
- Journal Title
  
  European Journal of Pharmacology 571
  
  Pages: 180-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Cytoprotective effect of bis (1-oxy-2-pyridinethiolato) oxovanadiun (IV) on myocardial ischemia/reperfusion injury elicits inhibition of Fas ligand and Bim expression and elevation of FLIP expression.2007
- Author(s)
  Md. Shenuarin Bhuiyan, Masatoshi Shibuya, Norifumi Shioda, Shigeki Moriguchi, Jiro Kasahara, Yoshiharu Iwabuchi and Kohji Fukunaga
- Journal Title
  
  European Journal of Pharmacology 571
  
  Pages: 180-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790363
[Journal Article] Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia.2007
- Author(s)
  N. Shioda, F. Han, S. Moriguchi and K. Fukunaga
- Journal Title
  
  Journal of Neurochemistry 102
  
  Pages: 1506-1517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional a ctivities in mouse brain ischemia.2007
- Author(s)
  Norifumi Shioda, Feng Han, Shigeki Moriguchi and Kohji Fukunaga
- Journal Title
  
  Journal of Neurochemistry 102
  
  Pages: 1506-1517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790363
[Journal Article] Effects of ethanol on excitatory and inhibitory synaptic transmission in rat cortical neurons.2007
- Author(s)
  Shigeki Moriguchi, Xilong Zhao, William Marszalec, Jay Z Yeh and Toshio Narahashi
- Journal Title
  
  Alcoholism: Clinical and Experimental Research 31
  
  Pages: 89-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790363
[Journal Article] Cytoprotective effect of bis (1-oxy-2-pyridinethiolato) oxovanadiun (IV) on myocardial ischemia/reperfusion injury elicits inhibiton of Fas ligand and Bim expression and elevation of FLIP expression.2007
- Author(s)
  Md. Shenuarin Bhuiyan, Masatos hi Shibuya, Norifumi Shioda, Shigeki Moriguchi, Jiro Kasahara, Yoshiharu Iwabuchi and Kohji Fukunaga
- Journal Title
  
  European Journal of Pharmacology 571
  
  Pages: 180-188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18059003
[Journal Article] Activation of PI3K/Akt pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia.2007
- Author(s)
  Norifumi Shioda, Takao Ishigami, Feng Han, Shigeki Moriguchi, Masatoshi Shibuya, Yoshiharu Iwabuchi and Kohji Fukunaga
- Journal Title
  
  Neuroscience 148
  
  Pages: 221-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18059003
[Journal Article] Im balance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyoctyes.2007
- Author(s)
  Ying-Mei Lu, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Jiro Kasahara, Yasufumi Shirasaki, Zheng-Hong Qin and Kohji Fukunaga
- Journal Title
  
  Biochemical Pharmacology 74
  
  Pages: 1727-1737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790363
[Journal Article] Activation of PI3K/Akt pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia.2007
- Author(s)
  Norifumi Shioda, Takao Ishigami, Feng Han, Shigeki Moriguchi, Masatoshi Shibuya, Yoshiharu Iwabuchi and Kohji Fukunaga
- Journal Title
  
  Neuroscience 148
  
  Pages: 221-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790363
[Journal Article] Effects of ethanol on excitatory and inhibitory synaptic transmission in rat cortical neurons.2007
- Author(s)
  Shigeki Moriguchi, Xilong Zhao, William Marszalec, Jay Z Yeh and Toshio Narahashi
- Journal Title
  
  Alcoholism: Clinical and Experimental Research 31
  
  Pages: 89-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18059003
[Journal Article] Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes.2007
- Author(s)
  Y-M. Lu, N. Shioda, F. Han, S. Moriguchi, J. Kasahara, Y. Shirasaki, Z. H. Qin, K. Fukunaga.
- Journal Title
  
  Biochem Pharmacol. 74
  
  Pages: 1727-1737
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Journal Article] Nefiracetam potentiates NMDA receptor function via PKC activation and reduces magnesium block of NMDA receptor.2007
- Author(s)
  Shigeki Moriguchi, Norifumi Shioda, Hiroshi Maejima, Xilong Zhao, William Marszalec, Jay Z. Yeh, Kohji Fukunaga and Toshio Narahashi
- Journal Title
  
  Molecular Pharmacology 71
  
  Pages: 580-587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790363
[Journal Article] Decreased calcium/calmodulin-dependent protein kinase II and protein kinase C activities mediated impairment of hippocampal long-term potentiation in the olfactory bulbectomizen mice.2006
- Author(s)
  S.Moriguchi et al.
- Journal Title
  
  Journal of Neurochemistry 97
  
  Pages: 22-29
- Data Source
  KAKENHI-PROJECT-18790363
[Journal Article] Decreased of CaMKII and PKC activities mediate impairment of hippocampal long-term potentiation in the olfactory bulbectomized mice.2006
- Author(s)
  S.Moriguchi
- Journal Title
  
  J.Neurochem. in press
- Data Source
  KAKENHI-PROJECT-17024004
[Journal Article] Functional uncouping between Ca^<2+> release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilinsd.2006
- Author(s)
  S.Moriguchi et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. 103
  
  Pages: 10811-10816
- Data Source
  KAKENHI-PROJECT-18790363
[Journal Article] Functional uncoupling between Ca2+ release and afterhyperpolarization in mutant hippocampal neurons lacking junctophilinsd.2006
- Author(s)
  S.Moriguchi et al.
- Journal Title
  
  Proc. Natl. Acad. Sci. U.S.A. 103
  
  Pages: 10811-10816
- Data Source
  KAKENHI-PROJECT-18059003
[Journal Article] Decreased calcium/calmodulin-dependent protein kinase II and protein kinase C activities mediate impairment of hippocampal long-term potentiation in the olfactory bulbectomized mice.2006
- Author(s)
  S.Moriguchi et al.
- Journal Title
  
  Journal of Neurochemistry 97
  
  Pages: 22-29
- Data Source
  KAKENHI-PROJECT-18059003
[Journal Article] The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells.
- Author(s)
  QB.Liu, LL.Liu, YM.Lu, RR.Tao, JY.Huang, N.Shioda, S.Moriguchi, K.Fukunaga, F.Han, YJ. Lou
- Journal Title
  
  Toxicol.Appl.Pharmacol. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390150
[Patent] 認知機能改善剤2021
- Inventor(s)
  森口茂樹、岩渕好治
- Industrial Property Rights Holder
  森口茂樹、岩渕好治
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-042122
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-21K06794
[Patent] ベンゼン縮合環化合物、およびそれを含有する医薬組成物2019
- Inventor(s)
  森口茂樹、福永浩司、有澤美枝子、山口雅彦
- Industrial Property Rights Holder
  森口茂樹、福永浩司、有澤美枝子、山口雅彦
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-186242
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K06887
[Patent] アダマンチルメチルアミン誘導体およびその医薬としての使用2018
- Inventor(s)
  森口茂樹、福永浩司、岩渕好治
- Industrial Property Rights Holder
  森口茂樹、福永浩司、岩渕好治
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-150290
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-15K08583
[Patent] アダマンタン誘導体およびその使用2017
- Inventor(s)
  森口茂樹、福永浩司、岩渕好治
- Industrial Property Rights Holder
  森口茂樹、福永浩司、岩渕好治
- Industrial Property Rights Type
  特許
- Filing Date
  2017-01-26
- Overseas
- Data Source
  KAKENHI-PROJECT-15K08583
[Patent] 新規アダマンタン誘導体によるアルツハイマー病治療薬の開発2017
- Inventor(s)
  森口茂樹、福永浩司、岩渕好治
- Industrial Property Rights Holder
  森口茂樹、福永浩司、岩渕好治
- Industrial Property Rights Type
  特許
- Filing Date
  2017-03-31
- Overseas
- Data Source
  KAKENHI-PROJECT-15K08583
[Patent] 特願2016- 123922016
- Inventor(s)
  森口茂樹、福永浩司、岩渕好治
- Industrial Property Rights Holder
  森口茂樹、福永浩司、岩渕好治
- Industrial Property Rights Type
  特許
- Filing Date
  2016-01-26
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] アルツハイマー病モデル動物の記憶障害に対するプロポリスとメマンチンの併用効果2023
- Author(s)
  稲垣良、森口茂樹
- Organizer
  ミツバチサミット2023
- Invited
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] Na+/Ca2+ 交換輸送体3（NCX3）ヘテロ型欠損マウスにおける認知機能障害及び多動性行動に関する研究2023
- Author(s)
  稲垣良、喜多紗斗美、丹羽望、岩本隆宏、森口茂樹
- Organizer
  第66回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] 老化に伴う認知・精神機能障害とカルシウムシグナル2023
- Author(s)
  森口茂樹
- Organizer
  第97回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] Na+/Ca2+ 交換輸送体3（NCX3）ヘテロ型欠損マウスにおける多動性および社会性障害に関する研究2023
- Author(s)
  稲垣良、喜多紗斗美、丹羽望、岩本隆宏、福永浩司、森口茂樹
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] α7型ニコチン性アセチルコリン受容体賦活化によるSAMP10マウスのうつ様症状改善効果2023
- Author(s)
  稲垣良、森口茂樹
- Organizer
  第74回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] Na+/Ca2+ 交換輸送体3（NCX3）欠損マウスにおける多動性/認知機能障害に関する細胞内機序の解明2023
- Author(s)
  丹羽望、稲垣良、喜多紗斗美、岩本隆宏、福永浩司、森口茂樹
- Organizer
  第74回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] カルシウムシグナル賦活化を介した認知機能改善機序2023
- Author(s)
  森口茂樹
- Organizer
  第66回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] 疾患モデルマウスのシナプス機能回復と認知症治療への応用2022
- Author(s)
  森口茂樹
- Organizer
  第96回日本薬理学会年会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] プロポリスによる認知症既存薬との併用効果2022
- Author(s)
  森口茂樹、稲垣良、福永浩司
- Organizer
  第73回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] プロポリスによる細胞内カルシウムシグナル賦活化を介した認知機能改善効果2022
- Author(s)
  稲垣良、山國徹、森口茂樹
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] 恐怖記憶形成におけるKATPチャネルのメカニズム解明2022
- Author(s)
  稲垣良、福永浩司、森口茂樹
- Organizer
  第73回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] アルツハイマー病治療薬リード化合物の構造活性相関研究2021
- Author(s)
  奈良佑樹, 久我哲也, 笹野裕介, 森口茂樹, 岩渕好治
- Organizer
  第141回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] カルシウム恒常性破綻による認知・精神機能障害と病態機序の解2021
- Author(s)
  森口茂樹
- Organizer
  第93回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] ATP感受性カリウムチャネル Kir6.1の扁桃体依存性恐怖記憶の形成における役割2021
- Author(s)
  稲垣良、福永浩司、森口茂樹
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] カルシウムシグナルを介した認知・精神機能調節2021
- Author(s)
  森口茂樹
- Organizer
  第64回日本神経化学会大会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] 難治性うつ病の病態発症機序の解明2021
- Author(s)
  森口茂樹
- Organizer
  第95回日本薬理学会年会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-21K06794
[Presentation] アルツハイマー病周辺症状を標的とした新たな治療戦略2020
- Author(s)
  森口茂樹
- Organizer
  第63回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] Exploration of novel mechanism target for behavioral and psychological symptoms of Alzheimer’s disease2019
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第62回日本神経化学会大会（Neuro2019）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] 難治性うつ病モデルマウスにおけるニコチン性アセチルコリン受容体賦活化の改善効果2019
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第49回日本精神神経薬理学会（スポンサードシンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] アルツハイマー病創薬へのブレイクスルーを目指して2019
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第92回日本薬理学会年会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] KATP channel is novel target for Alzheimer’s disease therapeutics2018
- Author(s)
  Shigeki Moriguchi
- Organizer
  The 4th Japan-Taiwan Joint Symposium for Pharmaceutical Scineces （招待講演）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] KATPチャネルを標的としたアルツハイマー病創薬研究2018
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第48回日本神経精神薬理学会（シンポジウム）
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] アルツハイマー病中核・周辺症状を改善する新規治療薬の開発2018
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第26回創薬薬理フォーラム（招待講演）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] Development of novel Alzheimer’s disease therapeutics as target for KATP channel2018
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第61回日本神経化学会大会（シンポジウム）
- Data Source
  KAKENHI-PROJECT-18K06887
[Presentation] KATPチャネルを標的としたアルツハイマー病脳糖尿病仮説の実証2017
- Author(s)
  森口茂樹、福永浩司
- Organizer
  医療薬学フォーラム2017（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Abnormal amygdala-dependent fear memory in corticosterone-treated mice2017
- Author(s)
  稲垣良、森口茂樹、福永浩司
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] α7型ニコチン性アセチルコリン受容体の活性化によるCaMKIV欠損マウスのうつ様症状の改善効果2017
- Author(s)
  稲垣良、森口茂樹、阪上洋行、福永浩司
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Demonstration of brain diabetes theory of Alzheimer’s disease2017
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第47回日本神経精神薬理学会年会（シンポジウム）
- Invited
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Memantine improves cognitive deficits in APP23 mice via KATP channel inhibition2017
- Author(s)
  森口茂樹、矢吹悌、福永浩司
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] カルシウム恒常性破綻による難治性うつ症状とその治療法2017
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Invited
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Dysregulation of amygdala-dependent fear memory in corticosterone-treated mice2017
- Author(s)
  稲垣良、森口茂樹、福永浩司
- Organizer
  第47回日本神経精神薬理学会年会
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Reduced CaM kinase II and CaM kinase IV activities mediate cognitive deficits in NCKX2 heterozygous mice2016
- Author(s)
  森口茂樹、喜多紗斗美、矢吹悌、堀江恭二、竹田潤二、岩本隆宏、福永浩司
- Organizer
  第59回日本神経化学会大会
- Place of Presentation
  福岡
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] 難治性うつ病の新たな治療展開2016
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第18回応用薬理シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] CaMキナーゼII賦活化による新しい記憶学習機構2016
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] Sigma-1 receptor stimulation improves depressive-like behaviors and adult hippocampal neurogenesis in CaMKIV null mice.2015
- Author(s)
  Shigeki Moriguchi, Hiroyuki Sakagami and Kohji Fukunaga.
- Organizer
  Neuroscience 2015 (45th. Society for Neuroscience)
- Place of Presentation
  Chicago USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] NCKX2欠損マウスにおける認知機能障害の細胞内機序2015
- Author(s)
  森口茂樹、喜多紗斗美、矢吹悌、泉久尚、堀江恭二、竹田潤二、岩本隆宏、福永浩司
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] カルシウム恒常性破綻による認知・精神機能障害に関する神経精神薬理学的研究2015
- Author(s)
  森口茂樹
- Organizer
  第45回日本神経精神薬理学会年会
- Place of Presentation
  東京
- Year and Date
  2015-09-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Abnormal fear memory via enhancement of CaM kinase II and IV activities in Na+/Ca2+ exchanger type-1 heterozygous mice2015
- Author(s)
  森口茂樹、泉久尚、喜多紗斗美、阪上洋行、岩本隆宏、福永浩司
- Organizer
  第45回日本神経精神薬理学会年会
- Place of Presentation
  東京
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Abnormal fear memory via enhancement of CaM kinase II and IV activities in Na+/Ca2+ exchanger type-1 heterozygous mice2015
- Author(s)
  森口茂樹、泉久尚、喜多紗斗美、阪上洋行、岩本隆宏、福永浩司
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  東京
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] NCKX2欠損マウスにおける認知機能障害の細胞内機序2015
- Author(s)
  森口茂樹、喜多紗斗美、矢吹悌、泉久尚、堀江恭二、竹田潤二、岩本隆宏、福永浩司
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Sigma-1 receptor stimulation improves depressive-like behaviors and adult hippocampal neurogenesis in CaMKIV null mice.2015
- Author(s)
  Shigeki Moriguchi, Hiroyuki Sakagami, Kohji Fukunaga
- Organizer
  Neuroscience 2015.
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] Dysregulation of fear memory and CaM kinase II activity in NCX1 heterozygous mice2015
- Author(s)
  森口茂樹、泉久尚、喜多紗斗美、阪上洋行、岩本隆宏、福永浩司
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] Dysregulation of fear memory and CaM kinase II activity in NCX1 heterozygous mice2015
- Author(s)
  森口茂樹、泉久尚、喜多紗斗美、阪上洋行、岩本隆宏、福永浩司
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K08583
[Presentation] Role of Na+/Ca2+ exchanger in Alzheimer’s disease2014
- Author(s)
  Shigeki Moriguchi, Satomi Kita, Takahiro Iwamoto and Kohji Fukunaga
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] Sigma-1 receptor stimulation improves depressive-like behaviors in CaMKIV null mice2014
- Author(s)
  Yuzuru Sasaki, Shigeki Moriguchi, Hiroyuki Sakagami and Kohji Fukunaga
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] Aberrant behavioral sensitization by methamphetamine in junctophilin deficient mice2013
- Author(s)
  Shigeki Moriguchi, Miyuki Nisi, Hiroshi Takeshima and Kohji Fukunaga
- Organizer
  第56回日本神経化学会大会　Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] Sigma-1受容体の賦活化によるCaMKIV欠損マウスにおけるうつ様行動の改善効果2013
- Author(s)
  森口茂樹、佐々木譲、阪上洋行、福永浩司
- Organizer
  第15回応用薬理シンポジウム
- Place of Presentation
  品川
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] ジャンクトフィリン欠損マウスにおけるメタンフェタミン誘発行動逆耐性の形成異常2013
- Author(s)
  森口茂樹、西美幸、竹島浩、福永浩司
- Organizer
  第56回日本神経化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] Sigma-1受容体活性化によるCaMKIV欠損マウスにおけるうつ様症状の改善効果2013
- Author(s)
  森口茂樹、佐々木譲、阪上洋行、福永浩司
- Organizer
  第43回日本神経精神薬理学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] Sigma-1受容体の賦活化によるCaMKIV欠損マウスにおけるうつ様行動の改善効果2013
- Author(s)
  森口茂樹、佐々木譲、阪上洋行、福永浩司
- Organizer
  第15回応用薬理シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] 海馬歯状回におけるDHEAによるsigma-1受容体の賦活化による神経新生促進作用と抗うつ効果2013
- Author(s)
  森口茂樹、佐々木譲、田頭秀章、福永浩司
- Organizer
  第64回日本薬理学会北部会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] Stimulation of sigma-1 receptor improves depressive-like behaviors in CaMKIV null mice2013
- Author(s)
  Shigeki Moriguchi, Yuzuru Sasaki, Hiroyuki Sakagami and Kohji Fukunaga
- Organizer
  43th Society for Neuroscience; Annual Meeting
- Place of Presentation
  アメリカ・サンディエゴ
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] Stimulation of sigma-1 receptor improves depressive-like behaviors in CaMKIV null mice.2013
- Author(s)
  Shigeki Moriguchi, Yuzuru Sasaki, Hiroyuki Sakagami and Kohji Fukunaga
- Organizer
  43th. Society for Neuroscience ;Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] Sigma-1受容体活性化によるCaMKIV欠損マウスにおけるうつ様症状の改善効果2013
- Author(s)
  森口茂樹、佐々木譲、阪上洋行、福永浩司
- Organizer
  第43回日本神経精神薬理学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] 海馬歯状回におけるDHEAによるsigma-1受容体の賦活化と抗うつ作用2013
- Author(s)
  森口茂樹、山本由似、佐々木譲、宮嶋晃輔、田頭秀章、福永浩司
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Rivastigmineによる嗅球摘出（OBX）マウスの海馬歯状回における神経新生および抗うつ様作用の改善効果2013
- Author(s)
  Islam Md. Rashedul、森口茂樹、田頭秀章、福永浩司
- Organizer
  第43回日本神経精神薬理学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] Abnormal fear-related memory via enhancement of CaM kinase II and IV activities in Na+/Ca2+ exchanger type-1 deficit mice.2012
- Author(s)
  Shigeki Moriguchi, Shun Ishikawa, Satomi Kita, Issei Komuro, Takahiro Iwamoto and Kohji Fukunaga
- Organizer
  包括型脳科学研究推進支援ネットワーク　夏のワークショップ
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] NCX2欠損マウスにおける認知機能障害とCaMキナーゼIIおよびカルシニューリンの活性異常2012
- Author(s)
  森口茂樹、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Novel Alzheimer’s therapeutics, ST101 enhances acetylcholine release through T-type voltage-gated calcium channel.2012
- Author(s)
  Kohji Fukunaga, Yui Yamamoto and Shigeki Moriguchi
- Organizer
  Alzheimer’s Association of International Conference
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] 新生仔期腹側海馬(NVH)損傷ラットにおける認知機能障害のメカニズム2012
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Abnormal fear-related memory via enhancement of CaM kinase II and IV activities in Na+/Ca2+ exchanger type-1 deficit mice.2012
- Author(s)
  Shigeki Moriguchi, Shun Ishikawa, Satomi Kita, Issei Komuro, Takahiro Iwamoto and Kohji Fukunaga
- Organizer
  包括型脳科学研究推進支援ネットワーク夏のワークショップ
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] 新生仔期腹側海馬損傷ラットの統合失調症様認知機能障害モデル動物としての有用性2012
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  第42回日本神経精神薬理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] 新規アルツハイマー病治療薬候補化合物ST101はT型カルシウムチャネルを活性化して大脳皮質LTPを促進する2012
- Author(s)
  森口茂樹、塩田倫史、山本由似、田頭秀章、福永浩司
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] T-type voltage-gated calcium channel activated by ST101 is a novel molecular target as cognitive enhancer.2012
- Author(s)
  Shigeki Moriguchi and Kohji Fukunaga
- Organizer
  Alzheimer’s Association of International Conference
- Place of Presentation
  Vancouver Canada
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] MPTP 誘発性運動機能障害及び認知機能障害に対する nobiletin の改善効果2012
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、大泉康、福永浩司
- Organizer
  生体機能と創薬シンポジウム 2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] 新規アルツハイマー病治療薬候補化合物ST101はT型カルシウムチャネルを活性化して大脳皮質LTPを促進する2012
- Author(s)
  森口茂樹、塩田倫史、山本由似、田頭秀章、福永浩司
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Cognitive deficit via imbalance of CaM kinase II and calcineurin activities in Na+/Ca2+ exchanger type-2 knockout mice.2012
- Author(s)
  Shigeki Moriguchi, Satomi Kita, Issei Komuro. Takahiro Iwamoto and Kohji Fukunaga
- Organizer
  第55回日本神経化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] Novel Alzheimer's therapeutics, ST101 enhances acetylcholine release through T-type voltage-gated calcium channel2012
- Author(s)
  Fukunaga K, Yamamoto Y and Moriguchi S
- Organizer
  Alzheimer's Association of International Conference
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] T型カルシウムチャネル賦活化と認知機能調節2012
- Author(s)
  森口茂樹、塩田倫史、田頭秀章、福永浩司
- Organizer
  第42回日本神経精神薬理学会
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] 新規アルツハイマー病治療薬候補化合物ST101は海馬内アセチルコリン遊離を促進して認知機能を改善する2012
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] T型カルシウムチャネル賦活化と認知機能調節2012
- Author(s)
  森口茂樹、塩田倫史、田頭秀章、福永浩司
- Organizer
  第42回日本神経精神薬理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] 新生仔期腹側海馬(NVH)損傷ラットにおける認知機能障害のメカニズム2012
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 新規アルツハイマー病治療薬候補化合物ST101は海馬内アセチルコリン遊離を促進して認知機能を改善する2012
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] T-type voltage-gated calcium channel activated by ST101 is a novel molecular target as cognitive enhancer.2012
- Author(s)
  Shigeki Moriguchi and Kohji Fukunaga
- Organizer
  Alzheimer’s Association of International Conference
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] NCX2欠損マウスにおける認知機能障害とCaMキナーゼIIおよびカルシニューリンの活性異常2012
- Author(s)
  森口茂樹、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第14回応用薬理シンポジウム
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] Cognitive deficit via imbalance of CaM kinase II and calcineurin activities in Na+/Ca2+ exchanger type-2 knockout mice.2012
- Author(s)
  Shigeki Moriguchi, Satomi Kita, Issei Komuro. Takahiro Iwamoto and Kohji Fukunaga
- Organizer
  Neuroscience 2012 第 35 回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Characterization of novel Alzheimer's therapeutic, ST101 in brain functions2011
- Author(s)
  Yui Yamamoto, Norifumi Shioda, Shigeki Moriguchi, Kohji Fukunaga
- Organizer
  40th. Society for Neuroscience ; Annual Meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新生仔期腹側海馬(NVH)損傷ラットにおける認知機能障害とCaMKII活性低下の関連性2011
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  第50回記念日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Stimulation of sigma-1 receptor improves cognitive functions through CaMKII activation2011
- Author(s)
  Fukunaga K, Moriguchi S, Yamamoto Y, Shioda N
- Organizer
  Society for neuroscience, Neuroscience meeting 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] DHEA処置によるシグマ1受容体の活性化は嗅球摘出マウスにおける認知機能障害をCaMKII、PKC、ERKの活性化を介して改善する2011
- Author(s)
  森口茂樹、山本由似、生野達也、福永浩司、
- Organizer
  日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 新生仔期腹側海馬(NVH)損傷ラットにおけるCaMKII活性低下と認知機能障害2011
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  第13回ブレインサイエンス研究会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] DHEAによるsigma1受容体刺激はCaMKII、PKCおよびERKの活性化を介して嗅球摘出マウスにおける認知機能障害を改善する2011
- Author(s)
  森口茂樹、山本由似、福永浩司
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新生仔期腹側海馬(NVH)損傷ラットにおけるCaMKII 活性低下と認知機能障害2011
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  第13回ブレインサイエンス研究会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] Stimulation of sigma-1 receptor improves cognitive functions through CaMKII activation2011
- Author(s)
  Kohji Fukunaga, Shigeki Moriguchi, Yui Yamamoto, Norifumi Shioda
- Organizer
  40th.Society for Neuroscience ; Annual Meeting
- Place of Presentation
  Washington DC USA
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新規認知機能改善薬sunifiramの作用機序に関する研究2011
- Author(s)
  田中智哉、森口茂樹、福永浩司
- Organizer
  第50回記念日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] 嗅球摘出マウスにおけるシグマ1受容体活性化による認知機能障害の改善2011
- Author(s)
  森口茂樹、山本由似、福永浩司
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新規認知機能改善薬sunifiramの作用機序に関する研究2011
- Author(s)
  田中智哉、森口茂樹、福永浩司
- Organizer
  第50回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新生仔期腹側海馬(NVH)損傷ラットにおける認知機能障害とCaMKII活性低下の関連性2011
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  第50回記念日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Shioda, Stimulation of sigma-1 receptor improves cognitive functions through CaMKII activation2011
- Author(s)
  K. Fukunaga, S. Moriguchi, Y. Yamamoto, N.
- Organizer
  Neuroscience2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 新生仔期腹側海馬(NVH)損傷ラット前脳におけるCaKII機能低下と行動異常2011
- Author(s)
  矢吹悌、森口茂樹、中川西修、小野木弘志、只野武、塩田倫史、福永浩司
- Organizer
  第20回神経行動薬理若手研究者の集い
- Place of Presentation
  東京
- Year and Date
  2011-03-21
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] DHEA処置によるシグマ1受容体の活性化は嗅球摘出マウスにおける認知機能障害をCaMKII、PKC、ERKの活性化を介して改善する2011
- Author(s)
  森口茂樹、山本由似、生野達也、福永浩司
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] MPTP処置パーキンソン病モデルマウスにおける認知機能障害とCaMキナーゼII活性低下の関連性2011
- Author(s)
  森口茂樹、矢吹悌、福永浩司
- Organizer
  第41回日本神経精神薬理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新生仔期腹側海馬(NVH)損傷ラット前脳におけるCaMKII機能低下と行動異常2011
- Author(s)
  矢吹悌、森口茂樹、中川西修、小野木弘志、只野武、塩田倫史、福永浩司
- Organizer
  第20回神経行動薬理若手研究者の集い
- Place of Presentation
  東京
- Year and Date
  2011-03-21
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 嗅球摘出マウスにおけるシグマ1受容体活性化による認知機能障害の改善2011
- Author(s)
  森口茂樹、山本由似、福永浩司
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 新規認知機能改善薬sunifiramの作用機序に関する研究2011
- Author(s)
  田中智哉、森口茂樹、福永浩司
- Organizer
  第50回記念日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Sigma1受容体を介した認知機能調節2011
- Author(s)
  森口茂樹、山本由似、福永浩司
- Organizer
  第13回応用薬理シンポジウム
- Place of Presentation
  船橋
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新生仔期腹側海馬(NVH)損傷ラットにおける認知機能障害とCaMKII活性低下の関連性2011
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  第50回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新規認知機能改善薬sunifiram の作用機序に関する研究2011
- Author(s)
  田中智哉、森口茂樹、福永浩司
- Organizer
  第50回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 神経変性疾患モデルマウスを用いたカルシウム恒常性の制御と認知機能調節2011
- Author(s)
  森口茂樹
- Organizer
  平成23年度日本薬学会東北支部学術講演会
- Place of Presentation
  仙台
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] DHEA処置によるシグマ1受容体の活性化は嗅球摘出マウスにおける認知機能障害をCaMKII、 PKC、 BRKの活性化を介して改善する2011
- Author(s)
  森口茂樹、山本由似、生野達也、福永浩司
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Characterization of novel Alzheimer's therapeutic, ST101 in brain functions2011
- Author(s)
  Y.Yamamoto, N.Shioda, S.Moriguchi, K.Fukunaga
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] MPTP処置パーキンソン病モデルマウスにおける認知機能障害とCaMキナーゼII活性低下の関連性2011
- Author(s)
  森口茂樹、矢吹悌、福永浩司
- Organizer
  第20回日本臨床精神神経薬理学会第40回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Stimulation of sigma-1 receptor improves cognitive functions through CaMKII activation2011
- Author(s)
  Kohji Fukunaga, Shigeki Moriguchi, Yui Yamamoto, Norifumi Shioda
- Organizer
  40th. Society for Neuroscience ; Annual Meeting
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 嗅球摘出マウスにおけるシグマ1受容体活性化による認知機能障害の改善2011
- Author(s)
  森口茂樹、山本由似、福永浩司
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  石川
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Stimulation of sigma-1 receptor improves cognitive functions through Ca MKII activation2011
- Author(s)
  K.Fukunaga, S.Moriguchi, Y.Yamamoto, N.Shioda
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] MPTP処置パーキンソン病モデルマウスにおける認知機能障害とCaMキナーゼII活性低下の関連性2011
- Author(s)
  森口茂樹、矢吹悌、福永浩司
- Organizer
  第20回日本臨床精神神経薬理学会第40回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Characterization of novel Alzheimer's therapeutic, ST101 in brain functions2011
- Author(s)
  Yui Yamamoto, Norifumi Shioda, Shigeki Moriguchi, Kohji Fukunaga
- Organizer
  40th.Society for Neuroscience ; Annual Meeting
- Place of Presentation
  Washington DC USA
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] Characterization of novel Alzheimer's therapeutic, ST101 in brain functions2011
- Author(s)
  Y.Yamamoto, N.Shioda, S.Moriguchi, K.Fukunaga
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Stimulation of sigma-1 receptor improves cognitive functions through CaMKII activation2011
- Author(s)
  K.Fukunaga, S.Moriguchi, Y.Yamamoto, N.Shioda
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] NCX3欠損マウスにおける自発運動量の亢進と細胞内カルシウム恒常性の異常2010
- Author(s)
  森口茂樹、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第40回日本神経精神薬理学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] メタンフヱタミン誘発行動逆耐性の機能不全にはCaMキナーゼII活性異常が関与する2010
- Author(s)
  森口茂樹、竹島浩、福永浩司
- Organizer
  日本神経化学会(Neuro2010)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] CaMキナーゼIIとプロテインキナーゼCの活性化を介したPAFによる海馬シナプス伝達の増強2010
- Author(s)
  森口茂樹, 福永浩司
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] NCX3欠損マウスにおける自発運動量の充進と細胞内カルシウム恒常性の異常2010
- Author(s)
  森口茂樹、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第20回日本臨床精神神経薬理学会第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] メタンフェタミン誘発行動逆耐性の機能不全にはCaMキナーゼII量活性異常が関与する2010
- Author(s)
  森口茂樹、竹島浩、福永浩司
- Organizer
  第53回日本神経化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新生児期腹側海馬損傷ラット前頭前皮質と海馬におけるCaMKIIの機能低下2010
- Author(s)
  矢吹悌、森口茂樹、中川西修、小野木弘志、只野武、福永浩司
- Organizer
  第14回活性アミンに関するワークショップ
- Place of Presentation
  仙台
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] Memantine ameliorates the impairment of hippocampal long-term potentiation in olfactory bulbectomized mice2010
- Author(s)
  Shigeki Moriguchi, Yui Yamamoto, Norifumi Shioda and Kohji Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Impairment of cognitive function via decreased calcium/cakrnodulin-dependent protein kinase II activity in Na^+/Ca^<2+> exchanger type-2 deficit mice.2010
- Author(s)
  Shigeki Moriguchi, Satomi Kita, Takahiro Iwamoto, Kohji Fukunaga
- Organizer
  包括型脳科学研究推進支援ネットワーク夏のワークショップ
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 新規アルツハイマー治療薬の認知機能改善とうつ症状改善作用の神経機序2010
- Author(s)
  福永浩司, 塩田倫史, 山本由似, 森口茂樹
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Impairment of cognitive function via decreased calcium/cakmo dulin-dependent protein kinase II activity in Na^+/Ca^2+ exchanger type-2 deficit mice.2010
- Author(s)
  Shigeki Moriguchi, Satomi Kita, Takahiro Iwamoto, Kohji Fukunaga
- Organizer
  包括型脳科学研究推進支援ネットワーク夏のワークショップ
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Na+/Ca2+交換体(NCX)欠損マウスにおけるカルシウム/カルモデュリン依存性プロテインキナーゼIIの機能低下と認知機能障害2010
- Author(s)
  森口茂樹、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第61回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] NCX3欠損マウスにおける自発運動蟻の充進と細胞内カルシウム恒常性の異常2010
- Author(s)
  森口茂樹、喜多紗斗美、居本隆宏、福永浩司
- Organizer
  第20回日本臨床精神神経薬理学会第401回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] メタンフェタミン誘発行動逆耐性の機能不全にはCaMキナーゼII活性異常が関与する2010
- Author(s)
  森口茂樹、竹島浩、福永浩司
- Organizer
  日本神経化学会 (Neuro2010)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] A novel cogllitive eiihancer, Spino[lmidazo[1,2-A]Pyridine-3,2-Indan]一2(3H)-One (ZSET1446), promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice.2010
- Author(s)
  Kohji Fukunaga, Yui Yamamotn, Shigeki Moriguchi, Norifumi Shiada
- Organizer
  International Conference on Alzheimer' s Dolsease
- Place of Presentation
  ホノルル、USA
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Memantine ameliorates the impairment of hippocampal long-ter mpotentiation in olfactory bulbectomized mice.2010
- Author(s)
  Shigeki Moriguchi, Yui Yamamoto, Norifumi Shioda, Kohji Fukunaga
- Organizer
  International Conference on Alzheimer' s Disease
- Place of Presentation
  ホノルル、USA
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Impairment of cognitive function via decreased calcium/cakmodulin-dependent protein kinase II activity in Na+/Ca2+ exchanger type-2 deficit mice2010
- Author(s)
  Shigeki Moriguchi, Satomi Kita, Takahiro Iwamoto, Kohji Fukunaga
- Organizer
  包括型脳科学研究推進支援ネットワーク夏のワークショップ
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] Memantine ameliorates the impairment of hippocampal long-term potentiation in olfactory bulbectomized mice.2010
- Author(s)
  Shigeki Moriguchi, Yui Yamamote, Norifumi Shioda, Kohji Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  ホノルル、USA
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] A novel cognitive enhancer, Spino[Imidazo[1,2-A]Pyridine-3,2-Indan]-2(3H)-One (ZSET1446), promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice2010
- Author(s)
  Fukunaga K, Yamamoto Y, Moriguchi S and Shioda N
- Organizer
  InternationalConference on Alzheimer's Disease
- Place of Presentation
  Hawaii
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] A novel cognitive enhancer, Spino[Imidazo[1, 2-A] Pyridine-3, 2-Indan]-2(3H)-One (ZSET1446), promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice2010
- Author(s)
  Kohji Fukunaga, Yui Yamamoto, Shigeki Moriguchi and Norifumi Shioda
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 新生児期腹側海馬損傷ラットの前頭前皮質と海馬における興奮性神経伝達機能低下と統合失調症様行動評価2010
- Author(s)
  矢吹悌、森口茂樹、中川西修、小野木弘志、只野武、福永浩司
- Organizer
  第61回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新生仔期腹側海馬損傷ラットの前頭前皮質における興奮性神経伝達機能低下と統合失調症様行動評価2010
- Author(s)
  矢吹悌、森口茂樹、中川西修、小野木弘志、只野武、福永浩司
- Organizer
  第61回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Memantine ameliorates the impairment of hippocampal long-term potentiation in olfactory bulbectomized mice.2010
- Author(s)
  Shigeki Moriguchi, Yui Yamamoto, Norifumi Shioda, Kohji Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  ホノルル、USA
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] Na+/Ca2+交換体(NCX)欠損マウスにおけるカルシウム/カルモデュリン依存性プロテインキナーゼIIの機能低下と認知機能障害2010
- Author(s)
  森口茂樹、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第61回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] A novel cognitive enhancer, Spino[Imidazo[1,2-A]Pyridine-3,2-Indan]-2(3H)-One (ZSET1446), promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbect omized mice.2010
- Author(s)
  Kohji Fukunaga, Yui Yamamoto, Shigeki Moriguchi, Norifumi Shioda
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  ホノルル、USA
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] A novel cognitive enhancer, Spino[Imidazo[1,2-A]Pyridine-3,2-Indan]-2(3H)-One (ZSET1446), promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice.2010
- Author(s)
  Kohji Fukunaga, Yui Yamamoto, Shigeki Moriguchi, Norifumi Shioda
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  ホノルル、USA
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] フルボキサミンはSigma-1受容体を刺激してTACによる心筋障害を抑制する.2010
- Author(s)
  田頭秀章、Md.Shenuarin, Bhuiyan、塩田倫史、森口茂樹、福永浩司
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 新生仔期腹側海馬損傷ラット前頭前皮質と海馬におけるCaMKIIの機能低下2010
- Author(s)
  矢吹悌、森口茂樹、中川西修、小野木弘志、只野武、福永浩司
- Organizer
  第14回活性アミンに関するワークショップ
- Place of Presentation
  仙台
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] CaMキナーゼIIとプロテインキナーゼCの活性化を介したPAFによる海馬シナプス伝達の増強2010
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Na+/Ca2+交換体(NCX)欠損マウスにおけるカルシウム/カルモデュリン依存性プロテインキナーゼIlの機能低下と認知機能障害2010
- Author(s)
  森口茂樹、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第61回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 新生仔期腹側海馬損傷ラットの前頭前皮質における興奮性神経伝達機能低下と統合失調症様行動評価2010
- Author(s)
  矢吹悌、森口茂樹、中川西修、小野木弘志、只野武、福永浩司
- Organizer
  第61回日本薬理学会北部会
- Place of Presentation
  札幌
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] 新規アルツハイマー治療薬の認知機能改善とうつ症状改善作用の神経機序2010
- Author(s)
  福永浩司、塩田倫史、山本由似、森口茂樹
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22659012
[Presentation] Abnormal behaviors of methamphetamine-induced sensitization is associated with impaired CaM kinase II activity in neural junctophilin deficient mice.2010
- Author(s)
  Shigeki Moriguchi, Hiroshi Takeshima, Kohji Fukunaga
- Organizer
  平成22年度シナプス研究会「記憶学習行動の基盤としてのシナプス可塑性」
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22790509
[Presentation] 新生仔期腹側海馬損傷ラット前頭前皮質と海馬における機能低下2010
- Author(s)
  矢吹悌、森口茂樹、中川西修、小野木弘志、只野武、福永浩司
- Organizer
  第14回活性アミンに関するワークショップ
- Place of Presentation
  仙台
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] 認知機能改善薬ZSET1446の脳内アセチルコリン遊離作用2009
- Author(s)
  山本由似、韓峰、塩田倫史、森口茂樹、福永浩司
- Organizer
  第11回応用薬理シンポジウム
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Na+/Ca2+交換体の認知機能調節における役割2009
- Author(s)
  森口茂樹, 塩田倫史, 喜多紗斗美, 小室一成, 岩本隆宏, 福永浩司
- Organizer
  平成21年度生理学研究所研究会シナプス研究会「シナプス機能と病態」
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 嗅球摘出マウスにおける海馬内アセチルコリン遊離に対するZSET1446の促進作用2009
- Author(s)
  山本由似、韓峰、塩田倫史、森口茂樹、福永浩司
- Organizer
  第60回日本薬理学会北部会
- Place of Presentation
  富山
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Nobiletion-induced stimulation of CaMKII and CREB phosphorylation is associated with memory improvement after brain ischemia.2009
- Author(s)
  Y Yamamoto, N Shioda, F Han, S Moriguchi, N akira, YA, Mimaki Y, Sashida Y, Yamakuni T, Ohizumi Y, K Fukunaga
- Organizer
  22nd ISN/APSN joint meeting
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Na+/Ca2+交換体の認知機能調節における役割.2009
- Author(s)
  森口茂樹、塩田倫史、喜多紗斗美、小室一成、岩本隆宏、福永浩司
- Organizer
  平成21年度生理学研究所研究会シナプス研究会「シナプス機能と病態」
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Impairment of cognitive function through downregulation of CaM kinase II activation in Na^+/Ca^<2+> exchanger type-2 knockout mice2009
- Author(s)
  森口茂樹, 韓峰, 塩田倫史, 喜多紗斗美, 小室一成, 岩本隆宏, 福永浩司
- Organizer
  39th.Society for Neuroscience ; Annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 認知機能改善薬ZSET1446は嗅球摘出マウスにおける海馬アセチルコリン遊離を促進する.2009
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、山口芳正、日野正孝、福永浩司
- Organizer
  第39回日本神経精神薬理学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Essential role of diacylglycerol kinase beta(DGKss)in neurite spine formation, cognitive function, and memory.2009
- Author(s)
  Y.SHIRAI, T.KOZUKI, K.KAKEFUDA, S.MORIGUCHI, A.OYAGI, K.HORIE, M.SHIMAZAWA, K.FUKUNAGA, J.TAKEDA, N.SAITO, H.HARA
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] スパイン形成および記憶におけるジアシルグリセロールキナーゼβの重要性2009
- Author(s)
  白井康仁、上月健、掛札堅一、大八木篤、堀江恭二、森口茂樹、嶋澤雅光、福永浩司、竹田潤二、斉藤尚亮、原英彰
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Abberrant fear-related behaviors in BSRP-TKO mice2009
- Author(s)
  Shigeki Moriguchi, Tatsuya Ikuno, Hiroshi Takeshima, Kohji Fukunaga
- Organizer
  第39回日本神経精神薬理学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Nefiracetamによる興奮性および抑制性神経伝達は、ニコチン性アセチルコリン受容体により制御される.2009
- Author(s)
  森口茂樹、楢橋敏夫、福永浩司
- Organizer
  第52回日本神経化学会大会
- Place of Presentation
  群馬
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] ドネペジルによるマウス中隔野アセチルコリン神経保護作用2009
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館(学生シンポジウム)
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] PDGF-β遺伝子欠損マウスにおいて海馬スパインとシナプス可塑性の異常は記憶障害を引き起こす.2009
- Author(s)
  塩田倫史、森口茂樹、山本由似、松島貴子、笹原正清、福永浩司
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 認知機能改善薬ZSET1446は嗅球摘出マウスにおける海馬アセチルコリン遊離を促進する2009
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、山口芳正、日野正孝、福永浩司
- Organizer
  第39回日本神経精神薬理学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Nobiletin-induced stimulation of CaMKII and CREB phosphorylation is associated with memory improvement after brain ischemia2009
- Author(s)
  Yui Yamamoto, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Akira Nakajima, Akihito Yokosuka, Yoshihiro Mimaki, Yutaka Sashida, Tohru Yamakuni, Yasushi Ohizumi, Kohji Fukunaga
- Organizer
  22nd Biennial Meeting of the International Society for Neurochemistry
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] BSRP欠損マウス扁桃体におけるCaMKII活性亢進と恐怖条件付け学習異常との関連性2009
- Author(s)
  生野達也、森口茂樹、竹島浩、福永浩司
- Organizer
  第11回ブレインサイエンス研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 脳特異的受容体様タンパク質欠損マウスの不安様行動と扁桃体神経活動異常.2009
- Author(s)
  生野達也、森口茂樹、竹島浩、福永浩司
- Organizer
  第6回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] BSRP欠損マウス扁桃体におけるCaMKII活性亢進と恐怖条件付け学習障害との関連性.2009
- Author(s)
  生野達也、森口茂樹、竹島浩、福永浩司
- Organizer
  第11回ブレインサイエンス
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] CaMキナーゼII活性化と2型Na^+/Ca^<2+>交換体による認知機能調節の関連性2009
- Author(s)
  森口茂樹、韓峰、塩田倫史、喜多紗斗美、小室一成、岩本隆宏、福永浩司
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Na+/Ca2+交換体欠損マウスにおける認知機能障害にはカルシウム/カルモデュリン依存性プロテインキナーゼIIの活性低下が関与する2009
- Author(s)
  森口茂樹、韓峰、塩田倫史、喜多紗斗美、小室一成、岩本隆宏、福永浩司
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(口演)
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Na+/Ca2+交換体(NCX)type2欠損マウスにおける細胞内カルシウム異常と認知機能障害2009
- Author(s)
  森口茂樹、韓峰、塩田倫吏、喜多紗斗美、小室一成、岩本隆宏、福永浩司
- Organizer
  第18回神経行動薬理若手研究者の集い
- Place of Presentation
  横浜情報文化センター情文ホール
- Year and Date
  2009-03-19
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 恐怖条件付け学習異常とCaM Kinase II活性亢進との関連性2009
- Author(s)
  生野達也、森口茂樹、竹島浩、福永浩司
- Organizer
  第6回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Impairment of cognitive function through downregulation of CaM kinase II activation in Na+/Ca2+. exchanger type-2 knockout mice.2009
- Author(s)
  S.MORIGUCHI, F.HAN, N.SHIODA, S.KITA, I.KOMURO, T.IWAMOTO, K.FUKUNAGA
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] CaMKキナーゼII活性化と2型Na+/Ca2+交換体による認知機能調節の関連性.2009
- Author(s)
  森口茂樹、韓峰、塩田倫史、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Deficient of memory formation mediated by impairment of intracellular calcium homeostasis in neuronal junctophilin deficit mice2009
- Author(s)
  森口茂樹, 竹島浩, 福永浩司
- Organizer
  22nd Biennial Meeting of the International Society for Neurochemistry
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Na^+/Ca^<2+>交換体の認知機能調節における役割2009
- Author(s)
  森口茂樹、塩田倫史、喜多紗斗美、小室一成、岩本隆宏、福永浩司
- Organizer
  平成21年度シナプス研究会『シナプス機能と病態』
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 神経新生を促進する新しいアルツハイマー病治療薬ZSET1446(ST101)の神経作用機序2009
- Author(s)
  塩田倫史、韓峰、森口茂樹、山口芳正、日野正孝、福永浩司
- Organizer
  第6回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 神経新生を促進する新しいアルツハイマー病治療薬ZSET1446(ST101)の神経作用機序.2009
- Author(s)
  塩田倫史、韓峰、森口茂樹、山口芳正、日野正孝、福永浩司
- Organizer
  第6回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 嗅球摘出マウスにおける海馬内アセチルコリン遊離に対するZSET1446の促進作用2009
- Author(s)
  山本由似、韓峰、塩田倫史、森口茂樹、福永浩司
- Organizer
  第60回日本薬理学会北部会
- Place of Presentation
  富山
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 認知機能改善薬ZSET1446の脳内アセチルコリン遊離作用.2009
- Author(s)
  山本由似、韓峰、塩田倫史、森口茂樹、福永浩司
- Organizer
  第11回応用薬理シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] スパイン形成および記憶におけるジアシルグリセロールキナーゼβの重要性.2009
- Author(s)
  白井康仁、上月健、掛札賢一、大八木篤、堀江恭二、森口茂樹、嶋澤雅光、福永浩司、竹田潤二、齊藤尚亮、原英彰
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] PDGFR-β遺伝子欠損マウスにおいて海馬スパインとシナプス可塑性の異常は記憶障害を引き起こす2009
- Author(s)
  塩田倫史、森口茂樹、山本由似、松島貴子、笹原正清、福永浩司
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Nefiracetam による興奮性および抑制性神経伝達は、ニコチン性アセチルコリン受容体により制勧される2009
- Author(s)
  森口茂樹、楢橋敏夫、福永浩司
- Organizer
  第52回日本神経化学会
- Place of Presentation
  群馬
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Deficient of memory formation mediated by impairment of intracelluar calcium homeostasis in neuronal junctophilin deficit mice.2009
- Author(s)
  Shigeki Moriguchi, Takeshima Hiroshi, Kohji Fukunaga
- Organizer
  22nd ISN/APSN joint meeting
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 学習及び情動障害メカニズム解明のための統合的解析手法―行動薬理、電気生理、神経化学による多角的解析手法―2009
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第11回ブレインサイエンス研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Essential role of diacylglycerol kinase beta(DGKβ)in neurite spine formation, cognitive function, and memory2009
- Author(s)
  Yasuhito Shirai, Takeshi Kozuki, Kenichi Kakefuda, Shigeki Moriguchi, Atushi Oyagi, Kyoji Horie, Masamitsu Shimazawa, Kohji Fukunaga, Jun Takeda, Naoaki Saito, Hideaki Hara
- Organizer
  39th.Society for Neuroscience ; Annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] ラット大脳皮質神経細胞の興奮性および抑制性神経伝達におけるガランタミンならびにネフィラセタムの効果2008
- Author(s)
  森口茂樹、楢橋敏夫、福永浩司
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Deficit of methamphetamine-induced behavioral sensitization is associated with impaired CaM kinase II activity in neural junctophilin deficient mice2008
- Author(s)
  Shigeki Moriguchi, Hiroshi Takeshima and Kohji Fukunaga
- Organizer
  第38回日本神経精神薬理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Impairment of cognitive function via down-regulation of calcium / calmodulin-dependent protein kinase II in Na+ / Ca2+ exchanger (NCX2) knock-out mice2008
- Author(s)
  Shigeki Moriguchi, Fong Han, Satomi Kita, Issei Komuro, Takahiro Iwamoto and Kohji Fukunaga
- Organizer
  第51回日本神経化学会
- Place of Presentation
  富山国際会議場
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Potentiation of calcium/calmodulin-dependent protein kinase II benefits for cognitive enhancement in Alzheimer's disease patients2008
- Author(s)
  Shigeki Moriguchi, Feng Han, Norifumi Shioda, Toshio Narahashi and Kohii Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] A novel cognitive enhancer rescues olfactory bulbectomy-induced memory impairment through stimulation of CaMKII and PKC signalings in mouse hippocampus2008
- Author(s)
  Fang Han, Norifumi Shioda, Shigeki Moriguchi, Yoshimasa Yamaguchi, Masataka Hino and Kohji Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Impairment of cognitive function via down-regulation of calcium/calmodulin-dependent protein kinase II in Na+/Ca2+ exchanger (NCX2) knock-out mice2008
- Author(s)
  Shigeki Moriguchi, Feng Han, Satomi Kita, Issei Komuro. Takahiro Iwamoto, Kohji Fukunaga
- Organizer
  第51回日本神経化学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 嗅球摘出マウスにおけるDonepezilによるアセチルコリン神経保護作用2008
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  第47回日本薬学会東北支部大会
- Place of Presentation
  岩手
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] A novel cognitive enhancer rescues olfactory bulbectomy-induced memory impairment through stimulation of CaMKII and PKC signalings in mouse hippocampus2008
- Author(s)
  Fang Han, Norifumi Shioda, Shigeki Moriguchi, Yoshimasa Yamaguchi, Masataka Hino and Kohji Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] ラット大脳皮質神経細胞の興奮性および抑制性神経伝達におけるガランタミンならびにネフィラセタムの効果2008
- Author(s)
  森口茂樹、楢橋敏夫、福永浩司
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] A novel cognitive enhancer rescues olfactory bulbectomy-induced memory impairment through stimulation of CaMKII and PKC signalings in mouse hippocampus.2008
- Author(s)
  Fang Han, Norifumi Shioda, Shigeki Moriguchi, Yoshimasa Yamaguchi, Masataka Hino, Kohji Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 脳虚血に伴うCaMKII活性低下は学習記憶障害に関与している2008
- Author(s)
  山本由似、塩田倫史、森口茂樹、中島昌、山國徹、大泉康、福永浩司
- Organizer
  第10回ブレインサイエンス研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 嗅球摘出マウスにおけるDonepezilによるアセチルコリン神経保護作用2008
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  第47回日本薬学会東北支部大会
- Place of Presentation
  岩手医科大学薬学部(口演)
- Year and Date
  2008-10-26
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] A novel cognitive enhancer, ZSET1446 improves olfactory bulbectomy-induced memory impairment through CaMKII and PKC activation in mouse hippocampus.2008
- Author(s)
  Yui Yamamoto, Feng Han, Norifumi Shioda, Shigeki Moriguchi, Kohji Fukunaga
- Organizer
  XI Workshop on Apoptosis in Biology and Medicine
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 嗅球摘出マウスにおけるドネペジルによるアセチルコリン神経保護作用2008
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  第59回日本薬理学会北部会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 細胞外グルコースのCaMKIIおよびPKCの活性化による記憶学習の改善効果2008
- Author(s)
  森口茂樹、大村裕、福永浩司(口演)
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] The vanadium (IV) compound ameliorates OBX-induced neurodegeneration of the septo-hippocampal cholinergic neurons through Akt and ERK pathways2008
- Author(s)
  Kohji, Fukunaga, Feng Han, Shigeki Moriguchi and Norifumi Shioda
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 嗅球摘出マウスにおけるドネペジルによるナセチルコリン神経保護作用2008
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  第59回日本薬理学会北部会
- Place of Presentation
  仙台市情報・産業プラザ(口演)
- Year and Date
  2008-09-27
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] A novel cognitive enhancer, ZSET1446 improves olfactory bulbectomy-induced memory impairment through CaMKII and PKC activati on in mouse hibppocambus2008
- Author(s)
  Yui yamamoto,Feng Han,Norifumi Shioda,Shigeki Moriguchi, Kohii Fukunaga
- Organizer
  XI Workshop on Apoptosis in Biology and Medicine
- Place of Presentation
  Tohoku Pharmaceutical University(Poster)
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Na+/Ca2+交換体(NCX)による神経細胞内カルシウムと認知機能調節2008
- Author(s)
  森口茂樹、韓峰、塩田倫史、喜多紗斗美、小室一成、岩本隆宏、福永浩司
- Organizer
  トランスポーターワークショップIN福岡
- Place of Presentation
  福岡
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Deficit of methamphetamine-induced behavioral sensitization is associated with impaired CaM kinase II activity in neural junctophilin deficient mice2008
- Author(s)
  Shigeki Moriguchi, Hiroshi Takeshima and Kohji Fukunaga
- Organizer
  第38回日本神経精神薬理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 認知機能改善薬ZSET1466の海馬歯状回における神経新生促進効果とそのメカニズム2008
- Author(s)
  塩田倫史、韓峰、山本由似、森口茂樹、山口芳正、日野正孝、福永浩司(口演)
- Organizer
  第17回神経行動薬理若手研究者の集い
- Place of Presentation
  横浜情報文化センター
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Na^+/Ca^<2+>交換体(NCX)による神経細胞内カルシウムと認知機能調節2008
- Author(s)
  森口茂樹、韓峰、塩田倫史、喜多紗斗美、小室一成、岩本隆宏、福永浩司
- Organizer
  トランスポーターワークショップIN福岡
- Place of Presentation
  福岡
- Year and Date
  2008-02-11
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 新しい作用機序を有する認知機能改善薬の創薬研究2008
- Author(s)
  福永浩司森口茂樹、塩田倫史、山本由似、韓峰
- Organizer
  薬理学サマーセミナー2008
- Place of Presentation
  栃木
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Potentiation of calcium/calmodulin-dependent protein kinase II benefits for cognitive enhancement in Alzheimer's disease patients.2008
- Author(s)
  Shigeki Moriguchi, Feng Han, Norifumi Shioda, Toshio Narahashi, Kohji Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] アルツハイマー治療薬ドネペジルはアセチルコリン神経保護作用を有する2008
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  霧島フォーラム
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Impairment of cognitive function via down-regulation of calcium/calmodulin-dependent protein kinase II in Na^+/Ca^<2+>exchanger (NCX2) knock-out mice2008
- Author(s)
  Shigeki Moriguchi, Feng Han, Satomi Kita, Issei Komuro Takahiro Iwamoto and Kohji Fukunaga
- Organizer
  第51回日本神経化学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] 細胞内カルシウムの認知機能調節に関する研究2008
- Author(s)
  森口茂樹
- Organizer
  第30回東北薬学セミナー
- Place of Presentation
  仙台
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] The Vanadium (IV) compound ameliorates OBX-induced neurodegene ration of the septo-hippocampal cholinergic neurons through Akt and ERK pathways2008
- Author(s)
  Kohji Fukunaga, Feng Han, Shigeki Moriguchi and Norifumi Shioda
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 脳虚血に伴う学習記憶障害とCaMKII機能低下との関連性2008
- Author(s)
  山本由似、塩田倫史、森口茂樹、中島昌、山國徹、大泉康、福永浩司
- Organizer
  東北バイオサイエンス
- Place of Presentation
  仙台
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] The vanadium (IV) compound ameliorates OBX-induced neurodegeneration of the septo-hippocampal cholinergic neurons through Akt and ERK pathways.2008
- Author(s)
  Kohji Fukunaga, Feng Han, Shigeki Moriguchi, Norifumi Shioda
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-20790398
[Presentation] Potentiation of calcium / calmodulin-dependent protein kinase II benefits for cognitive enhancement in Alzheimer's disease patients2008
- Author(s)
  Shigeki Moriguchi, Feng Han, Norifumi Shioda, Toshio Narahashi and Kohji Fukunaga
- Organizer
  International Conference on Alzheimer's Disease
- Place of Presentation
  Chicago USA
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] ZSET1446 はCaMKIIとPKCを活性化して嗅球除去マウスの記憶障害を改善する2008
- Author(s)
  韓峰、塩田倫史、森口茂樹、山口芳正、目野正孝、福永浩司(口演)
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 脳虚血に伴うCaMKII活性低下は学習記憶障害に関与しそいる2008
- Author(s)
  山本由似、塩田倫史、森口茂樹、福永浩司
- Organizer
  第10回ブレインサイエンス
- Place of Presentation
  マリンテラスあしや(口演)
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 認知機能改善薬ZSET1446は嗅球摘出マウスにおける海馬の神経新生を促進してうつ症状を改善する2008
- Author(s)
  塩田倫史、韓峰、森口茂樹、山口芳正、日野正孝、福永浩司(口演)
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] アルツハイマー治療薬ドネペジルはアセチルコリン神経保護作用を有する2008
- Author(s)
  山本由似、塩田倫史、韓峰、森口茂樹、福永浩司
- Organizer
  第19回霧島神経薬理フォーラム
- Place of Presentation
  日本文理大学湯布院研修所(口演)
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] The chromatin-remodeling gene ATRX mutant mice exhibit abnormal behaviors and learning impairment related to ADHD2007
- Author(s)
  T Tokoro, H Beppu, S Moriguchi, N Shioda, K Fukunaga, E Hori, H Nishijo, I Kitajima and E Li
- Organizer
  37th. Society for Neuroscience ; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] Plastic effect of endogeneous satiety substance leptin on the higher brain function2007
- Author(s)
  Yutaka Oomura, Shuji Aou, Kohji Fukunaga and Shigeki Moriguchi
- Organizer
  The 7th Japan-Korea joint symposium of brain sciences, and cardiac and smooth muscles
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] 摂食による脳可塑性の活性化2007
- Author(s)
  大村裕、粟生修司、福永浩司、森口茂樹、佐々木和男
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] NefiracetamによるNMDA受容体賦活作用はprotein kinase Cを介する2007
- Author(s)
  森口茂樹、塩田倫史、楢橋敏夫、福永浩司(口演)
- Organizer
  第30回日本神経科学大会第50回日本神経化学会大会第17回日本神経回路学会大会(Neuro2007)
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 興奮性および抑制性神経伝達におけるNefiracetamならびにGalantamineの作用機序2007
- Author(s)
  森口茂樹、楢橋敏夫、福永浩司(口演)
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  北海道
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 摂食による脳可塑性の活性化2007
- Author(s)
  大村裕、粟生修司、福永浩司、森口茂樹、佐々木和男
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] 興奮性および抑制性神経伝達におけるNefiracetamならびにGalantamineの作用機序2007
- Author(s)
  森口茂樹、楢橋敏夫、福永浩司
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  札幌市
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] Plastic effect of endogeneous satiety substance leptin on the higher brain function2007
- Author(s)
  Yutaka Oomura, Shuji Aou, Kohji Fukunaga and Shigeki Moriguchi
- Organizer
  The 7th Japan-Korea joint symposium of brain sciences, and cardiac and smooth muscles
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] Deficit of memory formation in neural junctophilin deficient mice2007
- Author(s)
  Shigeki Moriguchi, Miyuki Nishi, Hiromu Yawo, Hiroshi Takeshima and Kohji Fukunaga
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] ehaviors in the olfactory bulbectomized mice2007
- Author(s)
  Moriguchi, M Morioka and K Fukunaga
- Organizer
  37th. Society for Neuroscience ; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] Conditional Heparin-binding epidermal growth factor-like growth factor (HB-EGF) knockout mice exhibit abnormal psychomotor behaviors2007
- Author(s)
  A Oyagi, Y Oida, S Moriguchi, K Kitaichi, D Nanba, M Shimazawa, K Yamaguchi, K Fukunaga, Y Furuta, S Higashiyama and H Hara
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] 摂食による脳可塑性の活性化2007
- Author(s)
  大村裕、粟生修司、福永浩司、森口茂樹、佐々木和男(口演)
- Organizer
  第30回日本神経科学大会第50回日本神経化学会大会第17回日本神経回路学会大会(Neuro2007)
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Conditional Heparin-binding epidermal growth factor-like growth factor (HB-EGF) knockout mice exhibit abnormal psychomotor behaviors2007
- Author(s)
  A Oyagi, Y Oida, S Moriguchi, K Kitaichi, D Nanba, M Shimazawa, K Yamaguchi, K Fukunaga, Y Furuta, S Higashiyama and H Hara
- Organizer
  37th. Society for Neuroscience ; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] Deficit of memory formation in neural junctophilin deficient mice2007
- Author(s)
  Shigeki Moriguchi, Miyuki Nishi, Hiromu Yawo, Hiroshi Takeshima and Kohji Fukunaga
- Organizer
  37th. Society for Neuroscience ; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] Effects of a novel cognitive enhancer, ZSET1446 on depressive behavior and neurogenesis in the dentate gyrus of olfactory bulbectomized mice.2007
- Author(s)
  Y Yamaguchi, N Shioda, F Han, S Moriguchi, M Hino and K Fukunaga(poster)
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Impairment of CaM kinase II underlies memory deficits and depressive behaviors in the olfactory bulbectomized mice2007
- Author(s)
  F Han, T Nakano, N Shioda, S Moriguchi, M Morioka and K Fukunaga
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] Plastic effect of endogeneous satiety substance leptin on the higher brain function.2007
- Author(s)
  Yutaka Oomura, Shuji Aou, Kohji Fukunaga and Shigeki Moriguchi(Oral)
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Conditional Heparin-binding epidermal growth factor-like growth factor (HB-EGF) knockout mice exhibit abnormal psychomotor behaviors.2007
- Author(s)
  A Oyagi, Y Oida, S Moriguchi, K Kitaichi, D Nanba, M Shimazawa, K Yamaguchi, K Fukunaga, Y Furuta, S Higashiyama and H Hara(poster)
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Effects of a novel cognitive enhancer, ZSET1446 on depressive behavior and neurogenesis in the dentate gyrus of olfactory bulbectomized mice2007
- Author(s)
  Y Yamaguchi, N Shioda, F Han, S Moriguchi, M Hino and K Fukunaga
- Organizer
  37th. Society for Neuroscience ; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] 興奮性および抑制性神経伝達におけるNefiracetamならびにGalantamineの作用機序2007
- Author(s)
  森口茂樹、楢橋敏夫、福永浩司
- Organizer
  第58回日本薬理学会北部会
- Place of Presentation
  札幌市
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] Effects of a novel cognitive enhancer, ZSET1446 on depressive behavior and neurogenesis in the dentate gyurs of olfactory bulbectomized mice2007
- Author(s)
  Y Yamaguchi, N Shioda, F Han, S Moriguchi, M Hino and K Fukunaga
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] NefiracetamによるNMDA受容体賦活作用はprotein kinase Cを介する2007
- Author(s)
  森口茂樹、塩田倫史、楢橋敏夫、福永浩司
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-18790363
[Presentation] The chromatin-remodeling gene ATRX mutant mice exhibit abnormal behaviors and learning impairment related to ADHD2007
- Author(s)
  T Tokoro, H Beppu, S Moriguchi, N Shioda, K Fukunaga, E Hori, H Nishijo, I Kitajima and ELi
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] NefiracetamによるNMDA受容体賦活作用はprotein kinase Cを介する2007
- Author(s)
  森口茂樹、塩田倫史、楢橋敏夫、福永浩司
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-18059003
[Presentation] 認知機能改善薬ZSET1446は嗅球摘出マウスの海馬歯状回における神経新生を促進し、うつ症状を改善する2007
- Author(s)
  塩田倫史、韓峰、森口芳樹、山口芳正、日野正孝、福永浩司(poster)
- Organizer
  生体機能と創薬シンポジウム2007
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] Impairment of CaM kinase II underlies memory deficits and depressive behaviors in the olfactory bulbectomized mice.2007
- Author(s)
  F Han, T Nakano, N Shioda, S Moriguchi, M Morioka and K Fukunaga(poster)
- Organizer
  37th. Society for Neuroscience; Annual Meeting
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390150
[Presentation] 海馬歯状回におけるDHEAによるsigma-1受容体の賦活化による神経新生促進作用と抗うつ効果
- Author(s)
  森口茂樹、佐々木譲、田頭秀章、福永浩司
- Organizer
  第64回日本薬理学会北部会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] アルツハイマー病モデルマウスにおいて発現低下している2型Na+/Ca2+交換体の機能解明
- Author(s)
  森口茂樹、喜多紗斗美、岩本隆宏、福永浩司
- Organizer
  第44回日本神経精神薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] アルツハイマー病におけるNa+/Ca2+交換体の役割
- Author(s)
  森口茂樹
- Organizer
  第4回福岡薬理・生理系研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] アルツハイマー型認知症治療薬memantineの抗うつ作用のメカニズム
- Author(s)
  杉村好彦、森口茂樹、塩田倫史、田頭秀章、福永浩司
- Organizer
  第51回日本薬学会東北支部大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Sigma-1受容体賦活化による認知機能障害およびうつ様症状の改善効果
- Author(s)
  森口茂樹、福永浩司
- Organizer
  第22回神経行動薬理若手研究者の集い
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] アルツハイマー病におけるNa+/Ca2+交換体の機能障害
- Author(s)
  森口茂樹、喜多紗斗美、深谷昌弘、阪上洋行、岩本隆宏、福永浩司
- Organizer
  第16回応用薬理シンポジウム
- Place of Presentation
  松島
- Year and Date
  2014-12-05 – 2014-12-06
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] CaMKIV欠損マウスのうつ様行動と海馬神経新生異常との関連性
- Author(s)
  佐々木譲、森口茂樹、阪上洋行、福永浩司
- Organizer
  第23回神経行動薬理若手研究者の集い
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] CaMKIV欠損マウスのうつ様行動とsigma-1受容体アゴニストの改善作用
- Author(s)
  佐々木譲、森口茂樹、阪上洋行、福永浩司
- Organizer
  第64回日本薬理学会北部会
- Place of Presentation
  旭川
- Data Source
  KAKENHI-PROJECT-25293124
[Presentation] アルツハイマー病モデルマウスにおけるNa+/Ca2+交換体の機能障害
- Author(s)
  森口茂樹、喜多紗斗美、深谷昌弘、阪上洋行、岩本隆宏、福永浩司
- Organizer
  第65回日本薬理学会北部会
- Place of Presentation
  福島
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] アルツハイマー病におけるNa+/Ca2+交換輸送体の制御機構
- Author(s)
  森口茂樹
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-24590653
[Presentation] 統合失調症モデル、新生仔期腹側海馬損傷ラットの認知機能障害メカニズム
- Author(s)
  矢吹悌、森口茂樹、塩田倫史、中川西修、小野木弘志、丹野孝一、只野武、福永浩司
- Organizer
  次世代を担う創薬・医療薬理シンポジウム 2012
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22390109
[Presentation] Sigma-1 receptor agonist and fluvoxamine rescue depressive behaviors in CaMKIV null mice
- Author(s)
  Fukunaga K, Sakagami H, Moriguchi S
- Organizer
  Experimental Biology 2015
- Place of Presentation
  Boston, USA
- Year and Date
  2015-03-28 – 2015-04-01
- Data Source
  KAKENHI-PROJECT-25293124

1. FUKUNAGA Kohji (90136721)

# of Collaborated Projects: 8 results

# of Collaborated Products: 246 results
2. IWABUCHI Yushiharu (20211766)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. SHIODA Norifumi (00374950)

# of Collaborated Projects: 3 results

# of Collaborated Products: 68 results
4. MORIOKA Motohiro (20295140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KASAHARA Jiro (10295131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. ITO Yoshihisa (50151551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. FUKUDA TAKAICHI (50253414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 澁谷正俊 (40359534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中川西修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 根本亙

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 西条寿夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 八尾寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 小山内実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 岩本隆宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 森寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 青木茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 阪上洋行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 田頭秀章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Moriguchi Shigeki 森口 茂樹

MORIGUCHI Shigeki 森口 茂樹

Research Projects

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Elucidation of mechanism of dementia target for KATP channelPrincipal Investigator

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Elucidation of the behavioral and psychological symptoms of dementia target for KATP channelsPrincipal Investigator

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Mechanisms of both cognitive deficits and behavioral and psychological symptoms of Alzheimer's disease in KATP channel mutant micePrincipal Investigator

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Drug development of novel Kir6.2 channel inhibitor target for Alzheimer'ddiseasePrincipal Investigator

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Functional significance of target molecule of cognitive enhancer ST101 and drug development

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Drug discovery study of Alzheimer's disease target for T-type calcium channel activationPrincipal Investigator

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Drug development targeting for regeneration of neurovascular units in neurodegenerative disorders

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Role of fatty acid-binding protein in the brain vulnerability in schizophrenia

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Development of Alzheimer's disease therapeutics mediate for enhancement of synaptic transmissionPrincipal Investigator

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Effect of cognitive function mediated by NMDA receptor activation of new nootropic drug.Principal Investigator

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Development of novel neuroprotective drugs targeting for neurovascular unit therapy.

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小胞体機能異常による細胞内カルシウムシグナルと記憶学習の障害Principal Investigator

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NMDA受容体グリシン結合部位を標的とした新規アルツハイマー病治療薬の創薬研究Principal Investigator

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Project Period (FY)

Moriguchi Shigeki 森口茂樹

MORIGUCHI Shigeki 森口茂樹