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Fukunaga Kohji  福永 浩司

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… Alternative Names

FUKUNAGA Kohji  福永 浩司

福永 浩司

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Researcher Number 90136721
Other IDs
External Links
Affiliation (Current) 2022: 東北大学, 薬学研究科, 名誉教授
Affiliation (based on the past Project Information) *help 2021: 東北大学, 薬学研究科, 名誉教授
2016 – 2020: 東北大学, 薬学研究科, 教授
2017: 東北大学, 大学院薬学研究科, 教授
2014 – 2015: 東北大学, 大学院薬学研究科, 教授
2011 – 2015: 東北大学, 薬学研究科(研究院), 教授 … More
2013: 東北大学, 薬学研究科(研究員), 教授
2007 – 2012: Tohoku University, 大学院・薬学研究科, 教授
2006: 東北大学, 大学院薬学研究科, 教授
2002 – 2005: Graduate School of Pharmaceutical Sciences, Tohoku University Department of Pharmacology, Professor, 大学院・薬学研究科, 教授
2002: 東北大学, 医学部, 教授
2002: 東北大学, 大学院・薬学研究院, 教授
1993 – 2001: Kumamoto University Associate Professor, 医学部, 助教授
1998: 熊本大学, 医学部, 講師
1990 – 1992: 熊本大学, 医学部, 講師
1987: 熊本大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
General pharmacology / Applied pharmacology / Biological Sciences / Biological pharmacy / Science and Engineering / Neurochemistry/Neuropharmacology / 応用薬理学・医療系薬学 / Neurochemistry/Neuropharmacology / Basic Section 48030:Pharmacology-related
Except Principal Investigator
Neurochemistry/Neuropharmacology … More / Science and Engineering / General pharmacology / Biological Sciences / Applied pharmacology / Risk sciences of radiation/Chemicals / Experimental pathology / Fusional basic brain science / Pharmacology in pharmacy / 応用薬理学・医療系薬学 / 環境影響評価(含放射線生物学) Less
Keywords
Principal Investigator
海馬 / シナプス可塑性 / CaMキナーゼII / NMDA受容体 / 長期増強 / グルタミン酸受容体 / カルモデュリン / 蛋白質燐酸化反応 / long-term potentiation / シナプシンI … More / MAPキナーゼ / CREB / アルツハイマー病 / T型カルシウムチャネル / NMDA receptor / Long-term potentiation / カルモデュリンキナーゼII / カルシウムイオン / 血小板活性化因子 / LTP / プロテインホスファターゼ2A / ドパミン / 薬物治療学 / アセチルコリン / パーキンソン病 / CaM kinase II / カルモデュリン依存性プロテインキナーゼII / プロテインホスファターゼ2C / アストロサイト / 逆行性伝達物質 / CAI領域 / CaMキナーゼIV / クラスタリング分子 / SAP102 / PSD-95 / 遅発性神経細胞死 / 脳虚血 / 一酸化窒素 / 統合失調症 / カルシウム / 嗅球摘出マウス / 認知機能 / バナジウム化合物 / 多価不飽和脂肪酸 / アルツハイマー病治療薬 / 血管再生 / CaMKII / 薬理学 / 脂肪酸結合蛋白質 / アラキドン酸 / アミロイドβ / ノビレチン / 筋萎縮性側索硬化症 / ミトコンドリア障害 / 筋萎縮側索硬化症 / Sigma-1受容体 / Ca^<2+> / CA1 / scaffold protein / 神経薬理学 / 脳・神経 / ミトコンドリア / CA^<2+> / 転写調節因子 / プロテインキナーゼC / CamキナーゼII / BDNF / 転写調節 / long-term potemtiation / プロテインホスファターゼ / 学習 / AMPA受容体 / 時計遺伝子 / 視交叉上核 / 概日リズム / マイクロアレイ / フィブリノーゲン / 松果体 / グルタミン酸 / メラトニン / 視交差上核 / アポトーシス / 一酸化窒素合成酵素 / 神経保護薬 / メタンフェタミン / 逆耐性現象 / ドパミン受容体 / NF-κB / 覚醒剤中毒 / D2受容体 / 神経可塑性 / 情動行動 / 脳血管障害 / 内皮型一酸化窒素合成酵素 / 脳血管保護作用 / 神経新生 / 内皮型-酸化窒素合成酵素 / 心臓型脂肪酸結合蛋白質 / ドパミンD2受容体 / 線条体 / カタレプシー / ノックアウトマウス / 帯状回皮質 / 脳由来神経栄養因子 / 恐怖行動 / ST101 / アミロイド前駆タンパク質 / 神経血管ユニット / 神経変性疾患 / 神経再生 / バナジウム有機錯体 / 心肥大 / ジストロフィン / eNOS / ドパミン D2L 受容体 / H-FABP / 扁桃体 / ドパミン神経 / ドパミンD2L受容体 / 情動行動異常 / 高次脳機能 / 錐体外路系障害 / シグマー1受容体 / 小胞体ストレス / メチルピルビン酸 / ALS治療薬 / sigma-1 受容体 / TDP-43 / TCA 回路 / ピルビン酸 / IP3 受容体 / 脳血管性認知症 / 抗うつ薬 / T型カルシウムチャネル / L-シトルリン / 認知機能障害 / プロテインキナ-ゼ / 小脳顆粒細胞 / Longーterm potentiation / 微小管付随蛋白質 / 培養神経細胞 / 脳の可塑性 / 微小管蛋白質 / Calmodulin / Protein kinase / Cerebellar granule cells / Hippocampal neurons / Glutamate / 培養細胞 / Hippocampus / Memory / Learning / Synaptic long-term potentiation / Glutamate receptor / Ca^<2+> mobilization / 自己燐酸化反応 / スパイン / カルシニューリン / autophosphorylation / hippocampus / synaptic plasticity / protein phosphatase 2A / ドーパミン受容体 / 興奮性シナプス / scafold protein / シナプス / PDZドメイン / カリウムチャネル / excitatory synapse / postsynaptic density / NE-dlg / SAPI02 / 心筋虚血 / カルモデュリン阻害剤 / 脳浮腫 / カルパイン / 脳保護薬 / 神経細胞死 / 中大脳動脈閉塞モデル / バナジウム / Akt / 脳梗塞 / 虚血耐性 / プロテインキナーゼ / Fasリガンド / Forkhead transcription factor / ニトロチロシン / brain ischemia / myocardial ischemia / calmodulin antagonist / nitric oxide / brain edema / calpain / vanadium compound / FABPリガンド / αシヌクレイン / FABP3 / α-シヌクレイン / シヌクレイノパチー / 脳神経疾患 / SA4503 / Sigma-1R / 神経化学 / 難治性希少疾患 / 自閉スペクトラム症 / アミノレブリン酸 / オキシトシン / 酸化ストレス / 記憶 / 自閉スペクトラム障害 / 遺伝子発現 / ミトコンドリア異常 / バルプロ酸 / 社会性行動 / バルプロ酸暴露マウス / バルプロ酸暴露ラット / ミトコンドリア機能障害 / 自閉症 / トレースアミン関連受容体 / 5-アミノレブリン酸 / 自閉症モデルマウス … More
Except Principal Investigator
CaMキナーゼII / CaM kinase II / グルタミン酸受容体 / カルモデュリン / 海馬 / カルシウム / 記憶 / シナプス伝達長期増強 / 遺伝子発現 / MAPキナーゼ / NG108-15細胞 / プロテインホスファターゼ / 蛋白質燐酸化反応 / 学習 / PC12細胞 / カルシニューリン / 長期増強 / 培養細胞 / 脳由来神経栄養因子(BDNF) / カルモデュリンキナーゼII / 転写因子 / アストロサイト / Ca^<2+> / アルツハイマー病 / 蛋白質燐酸化酵素 / 核内移行シグナル / 転写調節 / 脳由来神経栄養因子 / ノックアウトマウス / 燐酸化特異抗体 / NMDA受容体 / LTP / 自己燐酸化反応 / Hippocampus / Glutamate receptor / Calcium ion / cDNA / カルシウム動員 / テタヌス刺激 / 海馬切片 / 錐体細胞 / 神経細胞 / 細胞分化 / 分子生物学 / 神経細胞死 / 長期抑圧 / カルシウムイオン / 初代培養神経細胞 / インスリン分泌反応 / シナプシンI / MIN6細胞 / 内分泌撹乱物質 / エステロジェン受容体 / カルモジュリン依存性キナーゼ / 胎仔期 / 脳 / 1-ブロモプロパン / 発達障害 / GABA抑制 / アダマンタンアミン / アダマンタンアミノ酸 / 認知機能 / 小胞体 / CaMKII / 受容体 / whole-cell patch-clamp法 / 細胞内シグナル伝達 / 免疫組織化学 / Ca^<2+>動員 / Ca^<2+> mobilization / Memory / Learning / Synaptic long-term potentiation / Neuron / Glia / Enzyme activation / 後シナプス細胞 / 受容体刺激 / 細胞内応答 / CaMキナーゼ / Receptor / Cultured cell / 核移行シグナル / Nuclear localization signal / 細胞骨格蛋白質 / long-term potentiation / hippocampus / learning / memory / MAP kinase / CaMキナーゼIV / CaM kinase IV / calmodulin-dependent protein kinase II / NG108-15 cells / GM-CSF / 微小管付随蛋白質 / 微小管不随蛋白質2 / 可塑性 / CA1 / 転写調節因子 / サブトラクション / CAKβ / Pyk2 / チロシンキナーゼ / 遺伝子組替え実験 / 遺伝子組換え実験 / 顆粒細胞 / 小脳 / 小脳顆粒細胞 / 長期記憶 / 神経活動依存性 / 阻害薬 / プロモーター解析 / 時計遺伝子 / 体内時計 / サーカディアンリズム / 機能分子 / 睡眠リズム障害 / 睡眠相後退症候群 / 季節性感情障害患者 / リズム変異マウス / 遺伝子改変マウス / 生物時計 / 早期発現遺伝子 / トランスジェニックマウス / 視交叉上核 / 概日リズム / メラトニン / マルチ電極ディッシュ / Cry / リズムの消失 / アンチセンス / in situ hybridization / 作用臨界期 / 学習・記憶 / ジエチルスチルベストロール / 子宮内体位現象 / モーリス水迷路 / プロテオーム解析 / 胎仔期後期 / 受動的回避反応 / 海馬の長期増強 / 脳の性分化 / 臭素イオン / 興奮性 / 海馬スライス標本 / リン酸化酵素活性 / O1ah環化反応 / イオンチャネル / NMDA / 不斉合成 / アダマンタン誘導体 / アマンタジン / カルモジュリンキナーゼII / グルタミン酸 / 光学活性アダマンタン誘導体 / ギラリティー / 中枢神経 / ジャンクトフィリン / シナプス可塑性 / LTD / メタンフェタミン / 行動逆耐性 / 記憶学習機構 / BSRP / CaM Kinase II / 電気生理学的解析 / 血小板由来増殖因子 / 神経 / 虚血 / 行動 / 血管 / グリア細胞 / 神経幹細胞 / 高次脳機能 / PDGF / 修復 / 疾患モデル動物 / 脳発達障害 / エピジェネテイクス / クロマチンリモデリング / スパイン / 神経科学 / 脳神経疾患 / 応用動物 / 精神遅滞 / ATR-X症候群 / コンデショナルノックアウトマウス / ES細胞 / 精神運動発達障害 / クロマチンロモデリング / ATRX症候群 / ES細胞 / ST101 / T-type CGCCs / OBX mice / 記憶学習 / T-type VGCC / 認知機能改善効果 / T型VGCC / 認知機能調節 / 精神疾患 / ドパミン D2 受容体 / シグナル伝達 / PDGF 受容体 / Rabex-5 / 行動制御回路 / ドパミンD2L受容体 / PDGF 受容体-β / スプライスバリアント / 神経細胞特異性 / 大脳基底核 / 線条体遠心性ニューロン / ハンチントン病 / カルモデュリン依存性プロテインキナーゼ / ホスホランバン / 心筋小胞体 / 心筋細胞上清分画 / Ca^<2+>-ATPase / トロポニンI / ブラジキニン受容体 / アイソエンザイム / CaMキナ-ゼII / 細胞内Ca^<2+>ホメオスタシス / 酵素活性化反応 / 基質蛋白質燐酸化反応 / 細胞増殖因子 / Ca^<2+>イオノフォア / 細胞内カルシウム / プロテインホスファタ-ゼ阻害因子 / cultured cell / bradykinin receptor / glutamate receptor / autophosphorylation / isoenzyme / protein phosphorylation / シナプス活動長期増強 / 受容体阻害薬 / NMDA receptor / 副腎髄質細胞 / Calcium mobilization / Long-term potentiation / Culturesd cell / Ca^<2+>mobilization / Protein phospatases / Endogenous substrates / cAMP / Rafl / 細胞増殖 / 初代培養細胞 / 細胞系 / 脳切片 / C / EBPファミリー / Intracellular response / Second messenger / 細胞モデル / 遺伝子強制導入 / 安定クローン細胞 / 強制発現 / サブユニットアイソフォーム / 抗体 / 発現細胞 / MAP2 / 神経突起伸展反応 / ジブチリルcAMP / Cellular model / Gene insertion / Cloned stable cell / Overexpression / 神経細胞分化 / 微小管付随蛋白質2 / Alzheimer's disease / Calmodulin / Neuronal differentiation / Microtubule-associated protein 2 / PC12 cells / Antiphosphopeptide antibody / 蛋白質脱燐酸化反応 / protein phosphatase / protein dephosphorylation / 細胞内Ca^<2+> / 細胞内情報伝達 / 細胞機能 / CaMキナーゼキナーゼ / δサブユニット / 脳由来神経成長因子 / Signal transduction / Calcineurin / Cellular functions / カルモデュリンキナーザII / 神経突起形成 / 側頭葉てんかん / Cキナーゼ / MARCKS / Brain-derived neurotrophic factor (BDNF) / Cytoskeletal proteins / Naurite outgrowth / Temporal lobe epilepsy / インスリン分泌細胞 / 可変領域 / ゴルジ体 / Astrocyte / Gene expression / Insulin secretion / Synapsin I / Brain-derived neurotrophic factor / MIN6 cells / 後シナプス神経細胞 / 蛋白質リン酸化反応 / NE-dlg / gene expression / ETS転写因子 / 気道粘液 / 肺サーファクタント / 肺 / 上皮細胞 / 気道上皮細胞 / 慢性閉塞性呼吸器疾患 / グリチルリチン / prostanlandin E_2 / 11β-hydroxysteroid dehydrogenase / 肺胞上皮細胞 / MEF / ETS-2 / 漢方薬 / ETS transcription factor / airway mucin / pulmonary surfactant / lung / epithelial cells / 中枢神経毒性 / 脳スライス標本 / 神経毒性 / 1-bromopropane / neurotoxitity / brain slice / GABAergic inhibition / immunohistochemistry / signal transduction / メマンチン / KATPチャンネル / KATPチャネル / AD脳糖尿病仮説 / 認知・精神機能 / Memantine / うつ症状 / 新規アダマンタン誘導体 / memantine / Kir6.2チャネル / カルシウムイメージング法 Less
  • Research Projects

    (68 results)
  • Research Products

    (1,359 results)
  • Co-Researchers

    (98 People)
  •  Development of Therapeutics for Mitochondrial Impairment in Autism Spectrum DisordersPrincipal Investigator

    • Principal Investigator
      Fukunaga Kohji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Tohoku University
  •  Drug development by investigation of a-synucelin aggregation mechanism through FABPPrincipal Investigator

    • Principal Investigator
      Fukunaga Kohji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tohoku University
  •  Drug development improving mitochondrial pathology in Amyotrophic lateral sclerosisPrincipal Investigator

    • Principal Investigator
      Fukunaga Kohji
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tohoku University
  •  Drug development of novel Kir6.2 channel inhibitor target for Alzheimer'ddisease

    • Principal Investigator
      Moriguchi Shigeki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tohoku University
  •  階層的生物評価系を用いた脳機能改善薬の創製Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  Functional significance of target molecule of cognitive enhancer ST101 and drug developmentPrincipal Investigator

    • Principal Investigator
      Fukunaga Kohji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tohoku University
  •  Research on mechanisms of intracellular D2LR signaling

    • Principal Investigator
      Shioda Norifumi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pharmacology in pharmacy
    • Research Institution
      Tohoku University
  •  神経血管再生のシーズ探索と階層的生物評価系の確立Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  Drug discovery study of Alzheimer's disease target for T-type calcium channel activation

    • Principal Investigator
      MORIGUCHI Shigeki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tohoku University
  •  Novel function of sigma-1 receptor and therapeutics strategy for neurodegenerative disordersPrincipal Investigator

    • Principal Investigator
      FUKUNAGA KOHJI
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  Molecular pathological mechanisms of the brain development disorder using the chromatin-remodeling molecule ATRX gene knockout mouse

    • Principal Investigator
      KITAJIMA Isao
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Fusional basic brain science
    • Research Institution
      University of Toyama
  •  Drug development targeting for regeneration of neurovascular units in neurodegenerative disordersPrincipal Investigator

    • Principal Investigator
      FUKUNAGA Kohji
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tohoku University
  •  Role of fatty acid-binding protein in the brain vulnerability in schizophreniaPrincipal Investigator

    • Principal Investigator
      FUKUNAGA Kohji
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  Role of PDGF signal in normal and injured brain.

    • Principal Investigator
      SASAHARA Masakiyo
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Toyama
  •  脂肪酸結合蛋白質によるドパミン受容体調節と神経機能における役割Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  Development of novel neuroprotective drugs targeting for neurovascular unit therapy.Principal Investigator

    • Principal Investigator
      FUKUNAGA Kohji
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tohoku University
  •  新規グルタミン酸配座固定化分子の合成に基づく受容体機能探索子の創製

    • Principal Investigator
      渋谷 正俊
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  小胞体機能異常による細胞内カルシウムシグナルと記憶学習の障害

    • Principal Investigator
      森口 茂樹
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  デルタ型CaMキナーゼIIの中枢ドパミン神経可塑性における役割Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  キラルアダマンタンアミン類の合成に基づくグルタミン酸受容体機能解明ツールの創製

    • Principal Investigator
      IWABUCHI Yushiharu
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Tohoku University
  •  フロン代替化合物1-ブロモプロパンの次世代健康への影響

    • Principal Investigator
      FUETA Yukiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  中枢興奮薬の逆耐性現象における神経可塑性を標的とした創薬研究Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tohoku University
  •  内分泌撹乱物質の学習・記憶撹乱作用の作用臨界期とそのメカニズムに関する研究

    • Principal Investigator
      高濱 和夫
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Kumamoto University
  •  Drug development by signal transduction therapy in the ischemic brain injury.Principal Investigator

    • Principal Investigator
      FUKUNAGA Kohji
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Tohoku University
  •  内分泌攪乱物質の学習・記憶攪乱作用の作用臨界期とそのメカニズムに関する研究

    • Principal Investigator
      高濱 和夫
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Science and Engineering
    • Research Institution
      Kumamoto University
  •  カルモデュリン依存性プロテインキナーゼIIの神経細胞内局在とシナプス機能の調節

    • Principal Investigator
      山本 秀幸
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  Development of therapeutic ways on various pathological features in chronic obstructive pulmonary diseases

    • Principal Investigator
      MIYATA Takeshi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto University
  •  Brain slice techniques as neurotoxicity tests for 1-bromopropane

    • Principal Investigator
      FUETA Yukiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      University of Occupational and Environmental Health
  •  カルモデュリン依存性蛋白質燐酸化反応による脳由来神経栄養因子産生の調節機構

    • Principal Investigator
      山本 秀幸
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  海馬シナプス可塑性におけるカルモデュリンキナーゼIIの役割Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  生体時計の分子機構

    • Principal Investigator
      柴田 重信, 岡村 均
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Waseda University
      Kobe University
  •  時計遺伝子産物のリン酸化に関わる分子素過程の解明Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      Kumamoto University
  •  新規カルモデュリン拮抗薬の抗アポトーシス作用の神経薬理学的研究Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  Neuropharmacological studies of clustering molecules expressing in the excitatory synapsesPrincipal Investigator

    • Principal Investigator
      FUKUNAGA Kohji
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  Functional and structural diversity of variable domain of Ca^<2+>/calmodulin-dependent protein kinase II

    • Principal Investigator
      YAMAMOTO Hideyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  Molecular and cytobiological study on regulation of synapse

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  海馬シナプス伝達長期増強・長期抑圧の誘発と維持におけるプロテインキナーゼの役割Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  カルモデュリン依存性蛋白質燐酸化反応による神経栄養因子産生の調節に関する研究

    • Principal Investigator
      山本 秀幸
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  神経活動依存性遺伝子発現活性化機構の研究

    • Principal Investigator
      宮本 英七
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  海馬シナプス伝達長期増強の誘発と維持におけるプロテインキナーゼの役割Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  蛋白質燐酸化反応と障害神経細胞での軸索とシナプス再形成に関する分子生物学的研究

    • Principal Investigator
      山本 秀幸
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  Molecular cytobiological study on hippocampal LTP and LTD

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  Molecular cytobiological study on CaィイD12+ィエD1 signaling in the cells with cultured cells

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  Working mechanism of Ca^<2+>/calmodulin-dependent protein kinase II in synaptic plasticityPrincipal Investigator

    • Principal Investigator
      FUKUNAGA Kohji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  Molecular and cellular biological study about the abnormal neurite outgrowth and protein phosphorylation in temporal lobe epilepsy

    • Principal Investigator
      YAMAMOTO Hideyuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  海馬シナプス伝達長期増強の誘発と維持におけるプロテインキナーゼの役割Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  神経活動を制御する階層性遺伝子支配の解析

    • Principal Investigator
      滝口 正樹
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  神経伝達物質による細胞増殖,分化機構の研究

    • Principal Investigator
      宮本 英七
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  海馬シナプス伝達長期増強の誘発と維持におけるプロテインキナーゼの役割Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  海馬長期増強における逆行性伝達物質の作用機構に関する研究Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  Study on the mechanism of brain plasticity

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kumamoto University
  •  Intracellular responses by stimulation of receptors in neurons and related cells

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  Establishment of stable cells by induction of cDNAs of functional proteins and preparation of models for evaluation of drug efficacy for creation of new drugs

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  The roles in neuronal differentiation of Ca^<2+>/calmodulin-dependent phosphorylation of microtubule proteins

    • Principal Investigator
      YAMAMOTO Hideyuki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  海馬でのグルタミン酸受容体刺激によるシナプス伝達長期増強の分子機構Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  脳海馬シナプス伝達長期増強に関する分子生物学的研究

    • Principal Investigator
      宮本 英七
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  海馬長期増強に伴う遺伝子発現に関する分子薬理学的研究Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  神経細胞死とカルモデュリン依存性細胞骨格蛋白質燐酸化反応の分子細胞生物学的研究

    • Principal Investigator
      山本 秀幸
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  海馬でのグルタミン酸受容体刺激によるシナプス伝達長期増強の分子機構Principal Investigator

    • Principal Investigator
      福永 浩司
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  脳海馬シナプス伝達長期増強に関する分子生物学的研究

    • Principal Investigator
      宮本 英七
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  Ca^<2+>/カルモデュリン依存性微小管付随蛋白質燐酸化反応の分子細胞生物学的研究

    • Principal Investigator
      山本 秀幸
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  Molecular and Cellular Biological Study on the Actions of Intracellular Calcium Ion in Cultured Cells

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  Study on long-term potentiation of brain hippocampus

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kumamoto University
  •  Molecular pharmacological studies on the expression of synaptic plasticityPrincipal Investigator

    • Principal Investigator
      FUKUNAGA Kohji
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  The Cytophamacological Study on the Responses of the Receptors in the Cell System

    • Principal Investigator
      MIYAMOTO Eishichi
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Pharmacological studies of calmodulin-dependent tau factor phosphorylation in cultured cerebellar granule cells.Principal Investigator

    • Principal Investigator
      FUKUNAGA Kohji
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kumamoto Research (C)
  •  カルシニューリンの脳内における特徴的局在-大脳基底核疾患との関係

    • Principal Investigator
      宮本 英七
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  心筋におけるCa^<2+>ホメオスターシスの調節と収縮制御

    • Principal Investigator
      宮本 英七
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent

  • [Book] The Function of CaM Kinase II in Synaptic Plasticity and Spine Formation. Handobook of Neurochemistry and Molecular Neurobiology. Neural Signaling Mechanisms2009

    • Author(s)
      K. Fukunaga, N. Shioda, E. Miyamoto
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Book] Pathophysiological Relevance of Forkhead Transcription Factors in Brain Ischemia Forkhead Transcription Factor : Vital Elements in Biology and Medicine2009

    • Author(s)
      K. Fukunaga, N. Shioda
    • Publisher
      Landes Bioscience
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Book] 最近の話題:心肥大形成とカルシウムシグナル2003

    • Author(s)
      福永浩司
    • Total Pages
      1
    • Publisher
      日薬理誌
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370035
  • [Book] 脳血管障害の新しい創薬ターゲット分子2003

    • Author(s)
      福永浩司
    • Total Pages
      6
    • Publisher
      医学の歩み
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370035
  • [Book] 長期増強とCaMキナーゼ.Clinical Neuroscience2002

    • Author(s)
      福永浩司
    • Total Pages
      2
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370035
  • [Book] Differential role of CaM kinases II and IV activities in neuronal plasticity and memory.2002

    • Author(s)
      K.Fukunaga
    • Total Pages
      16
    • Publisher
      Research Signpost, Kerala, India
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370035
  • [Journal Article] Transcriptome analysis in hippocampus of rats prenatally exposed to valproic acid and effects of intranasal treatment of oxytosin2022

    • Author(s)
      Kazuya Matsuo, Yasuharu Shinoda, Nona Abolhassani, Yusaku Nakabeppu, Kohji Fukunaga
    • Journal Title

      Frontiers in Psychiatry

      Volume: 13

    • DOI

      10.3389/fpsyt.2022.859198

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03406
  • [Journal Article] Characterization of design grammar of peptides for regulating liquid droplets and aggregates of FUS2021

    • Author(s)
      Kamagata Kiyoto、Chiba Rika、Kawahata Ichiro、Iwaki Nanako、Kanbayashi Saori、Maeda Kana、Takahashi Hiroto、Hirano Atsushi、Fukunaga Koji、Ikeda Keisuke、Kameda Tomoshi
    • Journal Title

      Scientific Reports

      Volume: 11 Pages: 6643-6643

    • DOI

      10.1038/s41598-021-86098-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06571, KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
  • [Journal Article] Impaired Acquisition of Nicotine-Induced Conditioned Place Preference in Fatty Acid-Binding Protein 3 Null Mice2021

    • Author(s)
      Jia Wenbin、Wilar Gofarana、Kawahata Ichiro、Cheng An、Fukunaga Kohji
    • Journal Title

      Molecular Neurobiology

      Volume: 58 Pages: 2030-2045

    • DOI

      10.1007/s12035-020-02228-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
  • [Journal Article] An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 32021

    • Author(s)
      Fukui N, Yamamoto H, Miyabe M, Aoyama Y, Hongo K, Mizobata T, Kawahata I, Yabuki Y, Shinoda Y, Fukunaga K, Kawata Y.
    • Journal Title

      Journal of Biological Chemistry

      Volume: Apr 13 Pages: 100663-100663

    • DOI

      10.1016/j.jbc.2021.100663

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K06513, KAKENHI-PROJECT-19K07097
  • [Journal Article] Suppression of α-synuclein propagation after intrastriatal injection in FABP3 null mice.2021

    • Author(s)
      Matsuo Kazuya、Kawahata Ichiro、Melki Ronald、Bousset Luc、Owada Yuji、Fukunaga Kohji
    • Journal Title

      Brain Res

      Volume: 1760 Pages: 147383-147383

    • DOI

      10.1016/j.brainres.2021.147383

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19H04026, KAKENHI-PROJECT-18J20651, KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-20K11609
  • [Journal Article] Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress2021

    • Author(s)
      Cheng An、Wang Yi-fei、Shinoda Yasuharu、Kawahata Ichiro、Yamamoto Tetsunori、Jia Wen-bin、Yamamoto Hanae、Mizobata Tomohiro、Kawata Yasushi、Fukunaga Kohji
    • Journal Title

      Acta Pharmacologica Sinica

      Volume: 43 Pages: 552-562

    • DOI

      10.1038/s41401-021-00675-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06513, KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-19H03406
  • [Journal Article] Dopamine D2 Long Receptors Are Critical for Caveolae-Mediated α-Synuclein Uptake in Cultured Dopaminergic Neurons.2021

    • Author(s)
      Kawahata I, Sekimori T, Wang H, Wang Y, Sasaoka T, Bousset L, Melki R, Mizobata T, Kawata Y, Fukunaga K.
    • Journal Title

      Biomedicines

      Volume: 9 Issue: 1 Pages: 49-49

    • DOI

      10.3390/biomedicines9010049

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K06513, KAKENHI-PROJECT-19K07097
  • [Journal Article] Epidermal Fatty Acid-Binding Protein 5 (FABP5) Involvement in Alpha-Synuclein-Induced Mitochondrial Injury under Oxidative Stress2021

    • Author(s)
      Wang Yifei、Shinoda Yasuharu、Cheng An、Kawahata Ichiro、Fukunaga Kohji
    • Journal Title

      Biomedicines

      Volume: 9 Pages: 110-110

    • DOI

      10.3390/biomedicines9020110

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
  • [Journal Article] T-type Ca2+ channel enhancer SAK3 administration improves the BPSD-like behaviors in AppNL?G-F/NL?G-F knock-in mice2021

    • Author(s)
      Degawa Tomohide、Kawahata Ichiro、Izumi Hisanao、Shinoda Yasuharu、Fukunaga Kohji
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 146 Pages: 1-9

    • DOI

      10.1016/j.jphs.2021.02.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-19H03406
  • [Journal Article] Fatty Acid-Binding Proteins Aggravate Cerebral Ischemia-Reperfusion Injury in Mice2021

    • Author(s)
      Guo Qingyun、Kawahata Ichiro、Degawa Tomohide、Ikeda-Matsuo Yuri、Sun Meiling、Han Feng、Fukunaga Kohji
    • Journal Title

      Biomedicines

      Volume: 9 Pages: 529-529

    • DOI

      10.3390/biomedicines9050529

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07129
  • [Journal Article] Impact of Fatty Acid-Binding Proteins in α-Synuclein-Induced Mitochondrial Injury in Synucleinopathy2021

    • Author(s)
      Cheng An、Jia Wenbin、Kawahata Ichiro、Fukunaga Kohji
    • Journal Title

      Biomedicines

      Volume: 9

    • DOI

      10.3390/biomedicines9050560

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-19H03406
  • [Journal Article] T-Type Ca2+ Enhancer SAK3 Activates CaMKII and Proteasome Activities in Lewy Body Dementia Mice Model2021

    • Author(s)
      Xu Jing、Kawahata Ichiro、Izumi Hisanao、Fukunaga Kohji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22

    • DOI

      10.3390/ijms22126185

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-19H03406
  • [Journal Article] The Role of CaMKII and ERK Signaling in Addiction2021

    • Author(s)
      Jia Wenbin、Kawahata Ichiro、Cheng An、Fukunaga Kohji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Pages: 3189-3189

    • DOI

      10.3390/ijms22063189

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
  • [Journal Article] A novel fatty acid-binding protein 5 and 7 inhibitor ameliorates oligodendrocyte injury in multiple sclerosis mouse models2021

    • Author(s)
      Cheng An、Jia Wenbin、Kawahata Ichiro、Fukunaga Kohji
    • Journal Title

      eBioMedicine

      Volume: 72

    • DOI

      10.1016/j.ebiom.2021.103582

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07097, KAKENHI-PROJECT-19H03406
  • [Journal Article] Single Administration of the T-Type Calcium Channel Enhancer SAK3 Reduces Oxidative Stress and Improves Cognition in Olfactory Bulbectomized Mice2021

    • Author(s)
      Yuan Dian、Cheng An、Kawahata Ichiro、Izumi Hisanao、Xu Jing、Fukunaga Kohji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Pages: 741-741

    • DOI

      10.3390/ijms22020741

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
  • [Journal Article] 5-aminolevulinic acid inhibits oxidative stress and ameliorates autistic-like behaviors in prenatal valproic acid-exposed rats2020

    • Author(s)
      Kazuya Matsuo, Yasushi Yabuki, Kohji Fukunaga
    • Journal Title

      Neuropharmacology

      Volume: 168 Pages: 107975-107975

    • DOI

      10.1016/j.neuropharm.2020.107975

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-18J20651
  • [Journal Article] Intranasal Administration of Conditioned Medium from Cultured Mesenchymal Stem Cells Improves Cognitive Impairment in Olfactory Bulbectomized Mice2020

    • Author(s)
      Kojima Kazuhiro、Kawahata Ichiro、Izumi Hisanao、Yoshihara Sei-ichi、Oki Katsuyuki、Fukunaga Kohji
    • Journal Title

      Advances in Alzheimer's Disease

      Volume: 09 Pages: 47-56

    • DOI

      10.4236/aad.2020.93004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
  • [Journal Article] SAK3 Administration Improves Spine Abnormalities and Cognitive Deficits in AppNL-G-F/NL-G-F Knock-in Mice by Increasing Proteasome Activity through CaMKII/Rpt6 Signaling2020

    • Author(s)
      Izumi Hisanao、Kawahata Ichiro、Shinoda Yasuharu、Helmstetter Fred J.、Fukunaga Kohji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Pages: 3833-3833

    • DOI

      10.3390/ijms21113833

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
  • [Journal Article] Anti-Epileptic Effects of FABP3 Ligand MF1 through the Benzodiazepine Recognition Site of the GABAA Receptor2020

    • Author(s)
      Yabuki Yasushi、Liu Jiaqi、Kawahata Ichiro、Izumi Hisanao、Shinoda Yasuharu、Koga Kohei、Ueno Shinya、Shioda Norifumi、Fukunaga Kohji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Pages: 5525-5525

    • DOI

      10.3390/ijms21155525

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21400, KAKENHI-PUBLICLY-19H05221, KAKENHI-PROJECT-17H04319, KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-20H03393, KAKENHI-PROJECT-18K08846, KAKENHI-PROJECT-19K07097
  • [Journal Article] Fatty Acid Binding Protein 5 Mediates Cell Death by Psychosine Exposure through Mitochondrial Macropores Formation in Oligodendrocytes2020

    • Author(s)
      Cheng An、Kawahata Ichiro、Fukunaga Kohji
    • Journal Title

      Biomedicines

      Volume: 8 Pages: 635-635

    • DOI

      10.3390/biomedicines8120635

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03406, KAKENHI-PROJECT-19K07097
  • [Journal Article] Correction: T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice2019

    • Author(s)
      Wang Shuo、Yabuki Yasushi、Matsuo Kazuya、Xu Jing、Izumi Hisanao、Sakimura Kenji、Saito Takashi、Saido Takaomi C.、Fukunaga Kohji
    • Journal Title

      PLOS ONE

      Volume: 14

    • DOI

      10.1371/journal.pone.0211590

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16J02855, KAKENHI-PROJECT-18J20651
  • [Journal Article] Combined citicoline and docosahexaenoic acid treatment improves cognitive dysfunction following transient brain ischemia2019

    • Author(s)
      Nakazaki Eri、Yabuki Yasushi、Izumi Hisanao、Shinoda Yasuharu、Watanabe Fumiko、Hishida Yukihiro、Kamimura Ayako、Fukunaga Kohji
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: pii: S1347-8613 Pages: 30023-30024

    • DOI

      10.1016/j.jphs.2019.02.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16J02855
  • [Journal Article] KY-226 Protects Blood?brain Barrier Function Through the Akt/FoxO1 Signaling Pathway in Brain Ischemia2019

    • Author(s)
      Sun Meiling、Shinoda Yasuharu、Fukunaga Kohji
    • Journal Title

      Neuroscience

      Volume: 399 Pages: 89-102

    • DOI

      10.1016/j.neuroscience.2018.12.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05219
  • [Journal Article] Development of FABP3 ligands that inhibit arachidonic acid-induced α-synuclein oligomerization2019

    • Author(s)
      Cheng An、Shinoda Yasuharu、Yamamoto Tetsunori、Miyachi Hiroyuki、Fukunaga Kohji
    • Journal Title

      Brain Research

      Volume: 1707 Pages: 190-197

    • DOI

      10.1016/j.brainres.2018.11.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05219
  • [Journal Article] Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA42019

    • Author(s)
      Tan Chao、Lu Nan-Nan、Wang Cheng-Kun、Chen Dan-Yang、Sun Ning-He、Lyu Hang、Korbelin Jakob、Shi Wei-Xing、Fukunaga Kohji、Lu Ying-Mei、Han Feng
    • Journal Title

      Neuron

      Volume: 101

    • DOI

      10.1016/j.neuron.2018.12.036

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219
  • [Journal Article] Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer’s disease therapy.2018

    • Author(s)
      Moriguchi S, Ishizuka T, Yabuki Y, Shioda N, Sasaki Y, Tagashira H, Yawo H, Yeh JZ, Sakagami H, Narahashi T, Fukunaga K.
    • Journal Title

      Molecular Psychiatry.

      Volume: 印刷中 Pages: 211-221

    • DOI

      10.1038/mp.2016.187

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01413, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-15K15025, KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-16K14574, KAKENHI-PROJECT-16K19024, KAKENHI-PROJECT-16K08265, KAKENHI-PROJECT-25250001
  • [Journal Article] The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice2018

    • Author(s)
      Izumi H, Shinoda Y, Saito T, Saido TC, Sato K, Yabuki Y, Matsumoto Y, Kanemitsu Y, Tomioka Y, Abolhassani N, Nakabeppu Y, Fukunaga K.
    • Journal Title

      Neuroscience

      Volume: 377 Pages: 87-97

    • DOI

      10.1016/j.neuroscience.2018.02.031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15456, KAKENHI-PROJECT-17H01391, KAKENHI-PROJECT-16J02855, KAKENHI-PROJECT-16K20909, KAKENHI-PROJECT-16H05219
  • [Journal Article] Inhibition of Nicotine Dependence by Curcuminoid Is Associated with Reduced Acetylcholinesterase Activity in the Mouse Brain2018

    • Author(s)
      Wilar Gofarana、Anggadiredja Kusnandar、Shinoda Yasuharu、Fukunaga Kohji
    • Journal Title

      Pharmacology

      Volume: 102 Pages: 223-232

    • DOI

      10.1159/000492154

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219
  • [Journal Article] Different PDGF Receptor Dimers Drive Distinct Migration Modes of the Mouse Skin Fibroblast.2018

    • Author(s)
      Yamada Kohta、Hamashima Takeru、Ishii Yoko、Yamamoto Seiji、Okuno Noriko、Yoshida Naofumi、Yamada Moe、Huang Ting Ting、Shioda Norifumi、Tomihara Kei、Fujimori Toshihiko、Mori Hisashi、Fukunaga Kohji、Noguchi Makoto、Sasahara Masakiyo
    • Journal Title

      Cell Physiol Biochem.

      Volume: 51 Pages: 1461-1479

    • DOI

      10.1159/000495594

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-16K08265
  • [Journal Article] Neuroprotective effects of protein tyrosine phosphatase 1B inhibitor on cerebral ischemia/reperfusion in mice2018

    • Author(s)
      Sun Meiling、Izumi Hisanao、Shinoda Yasuharu、Fukunaga Kohji
    • Journal Title

      Brain Research

      Volume: 1694 Pages: 1-12

    • DOI

      10.1016/j.brainres.2018.04.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16J02855
  • [Journal Article] FABP3 in the Anterior Cingulate Cortex Modulates the Methylation Status of the Glutamic Acid Decarboxylase67 Promoter Region.2018

    • Author(s)
      Yamamoto Yui、Kida Hiroyuki、Kagawa Yoshiteru、Yasumoto Yuki、Miyazaki Hirofumi、Islam Ariful、Ogata Masaki、Yanagawa Yuchio、Mitsushima Dai、Fukunaga Kohji、Owada Yuji
    • Journal Title

      Journal of Neuroscience

      Volume: 38 Pages: 10411-10423

    • DOI

      10.1523/jneurosci.1285-18.2018

    • NAID

      130007813353

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K00856, KAKENHI-PROJECT-18K19723, KAKENHI-PROJECT-16H05116, KAKENHI-PROJECT-16H05129, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K18366, KAKENHI-PROJECT-17K15539
  • [Journal Article] Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome.2018

    • Author(s)
      Shioda Norifumi、Yabuki Yasushi、Yamaguchi Kouya、Onozato Misaki、Li Yue、Kurosawa Kenji、Tanabe Hideyuki、Okamoto Nobuhiko、Era Takumi、Sugiyama Hiroshi、Wada Takahito、Fukunaga Kohji
    • Journal Title

      Nat Med.

      Volume: 24 Pages: 802-813

    • DOI

      10.1038/s41591-018-0018-6

    • NAID

      120006488578

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K08265, KAKENHI-PROJECT-16H06356
  • [Journal Article] Reduced CaM kinase II and CaM Kinase IV activities underlie cognitive deficits in NCKX2 heterozygous mice2018

    • Author(s)
      Moriguchi S, Kita S, Yabuki Y, Inagaki R, Izumi H, Sasaki Y, Tagashira H, Horie K, Takeda J, Iwamoto T, Fukunaga K.
    • Journal Title

      Mol Neurobiol

      Volume: 55(5) Pages: 3889-3900

    • DOI

      10.1007/s12035-017-0596-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08610, KAKENHI-PROJECT-16K19024, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-16K14574, KAKENHI-PROJECT-16K08565
  • [Journal Article] Myt1l induced direct reprogramming of pericytes into cholinergic neurons2018

    • Author(s)
      Liang Xing-Guang、Tan Chao、Wang Cheng-Kun、Tao Rong-Rong、Huang Yu-Jie、Ma Kui-Fen、Fukunaga Kohji、Huang Ming-Zhu、Han Feng
    • Journal Title

      CNS Neuroscience & Therapeutics

      Volume: 24 Pages: 801-809

    • DOI

      10.1111/cns.12821

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219
  • [Journal Article] T-type calcium channel enhancer SAK3 produces anti-depressant-like effects by promoting adult hippocampal neurogenesis in olfactory bulbectomized mice.2018

    • Author(s)
      Xu Jing、Yabuki Yasushi、Yu Mengze、Fukunaga Kohji
    • Journal Title

      J Pharmacol Sci

      Volume: 137 Pages: 333-341

    • DOI

      10.1016/j.jphs.2018.07.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-17K15456
  • [Journal Article] Aberrant Amygdala-dependent Fear Memory in Corticosterone-treated Mice2018

    • Author(s)
      Ryo Inagaki, Shigeki Moriguchi and Kohji Fukunaga
    • Journal Title

      Neuroscience

      Volume: 388 Pages: 448-459

    • DOI

      10.1016/j.neuroscience.2018.08.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06887, KAKENHI-PROJECT-16H05219
  • [Journal Article] Acute Treatment with T-Type Calcium Channel Enhancer SAK3 Reduces Cognitive Impairments Caused by Methimazole-Induced Hypothyroidism Via Activation of Cholinergic Signaling2018

    • Author(s)
      Husain N, Yabuki Y, Shinoda Y, Fukunaga K.
    • Journal Title

      Pharmacology

      Volume: 101 Pages: 309-321

    • DOI

      10.1159/000488083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15456, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K14574
  • [Journal Article] SA4503, A Potent Sigma-1 Receptor Ligand, Ameliorates Synaptic Abnormalities and Cognitive Dysfunction in a Mouse Model of ATR-X Syndrome.2018

    • Author(s)
      Yamaguchi Kouya、Shioda Norifumi、Yabuki Yasushi、Zhang Chen、Han Feng、Fukunaga Kohji
    • Journal Title

      Int J Mol Sci.

      Volume: 19 Pages: 2811-2811

    • DOI

      10.3390/ijms19092811

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K08265
  • [Journal Article] 14.Reduced expression of Na+/Ca2+ exchangers is associated with cognitive deficits seen in Alzheimer’s disease model mice.2018

    • Author(s)
      Moriguchi S, Kita S, Fukaya M, Osanai M, Inagaki R, Sasaki Y, Izumi H, Horie K, Takeda J, Saito T, Sakagami H, Saido TC, Iwamoto T, Fukunaga K
    • Journal Title

      Neuropharmacology

      Volume: 131 Pages: 291-303

    • DOI

      10.1016/j.neuropharm.2017.12.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08486, KAKENHI-PROJECT-16K08565, KAKENHI-PUBLICLY-17H05543, KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-17K08610
  • [Journal Article] Endocytosis following dopamine D2 recoptor activation is critical for nouronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons.2017

    • Author(s)
      Shioda N, Yabuki Y, Wang Y, Uchigashima M, Hikida T, Sasaoka T, Mori H, Watanabc M, Sasahara M, Fukunaga K
    • Journal Title

      Molecular Psychiatry

      Volume: 印刷中 Issue: 8 Pages: 1205-1222

    • DOI

      10.1038/mp.2016.200

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06568, KAKENHI-PROJECT-15H04275, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-25293093, KAKENHI-PROJECT-26290029, KAKENHI-PROJECT-16K14574, KAKENHI-PROJECT-16K14579, KAKENHI-PROJECT-16K08265, KAKENHI-PUBLICLY-16H01606, KAKENHI-PROJECT-16H06276
  • [Journal Article] Pharmacological properties of SAK3, a novel T-type voltage-gated Ca2+ channel2017

    • Author(s)
      Yabuki Y, Matsuo K, Izumi H, Haga H, Yoshida T, Wakamori M, Kakehi A, Sakimura K, Fukuda T, Fukunaga K.
    • Journal Title

      Neuropharmacology

      Volume: 117 Pages: 1-13

    • DOI

      10.1016/j.neuropharm.2017.01.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H04650, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-15K11036, KAKENHI-PROJECT-15K15681, KAKENHI-PROJECT-16K14574
  • [Journal Article] Novel spiroimidazopyridine derivative SAK3 improves methimazole-induced cognitive deficits in mice2017

    • Author(s)
      Noreen H, Yabuki Y, Fukunaga K.
    • Journal Title

      Neurochem. Int.

      Volume: - Pages: 91-99

    • DOI

      10.1016/j.neuint.2017.03.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-16K14574
  • [Journal Article] Pathophysiological role of sigma-1 receptor in Amyotrophic lateral sclerosis2017

    • Author(s)
      福永 浩司、篠田 康晴
    • Journal Title

      生化学

      Volume: 89 Issue: 1 Pages: 106-110

    • DOI

      10.14952/SEIKAGAKU.2017.890106

    • NAID

      40021119824

    • ISSN
      0037-1017
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-16K14574
  • [Journal Article] Combined Memantine and Donepezil Treatment Improves Behavioral and Psychological Symptoms of Dementia-Like Behaviors in Olfactory Bulbectomized Mice2017

    • Author(s)
      Yabuki Y, Matsuo K, Hirano K, Shinoda Y, Moriguchi S, Fukunaga K.
    • Journal Title

      Pharmacology.

      Volume: 99 Pages: 160-171

    • DOI

      10.1159/000452839

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-16K14574, KAKENHI-PROJECT-16H05219
  • [Journal Article] The T-type calcium channel enhancer SAK3 inhibits neuronal death following transient brain ischemia via nicotinic acetylcholine receptor stimulation2017

    • Author(s)
      Yabuki Y, Jing X, Fukunaga K.
    • Journal Title

      Neurochem. Int.

      Volume: 108 Pages: 272-281

    • DOI

      10.1016/j.neuint.2017.04.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15456, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K14574
  • [Journal Article] Stimulation of the Sigma-1 Receptor and the Effects on Neurogenesis and Depressive Behaviors in Mice2017

    • Author(s)
      Fukunaga K, Moriguchi S.
    • Journal Title

      Adv Exp Med Biol

      Volume: 964 Pages: 201-211

    • DOI

      10.1007/978-3-319-50174-1_14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K14574
  • [Journal Article] Combined l-citrulline and glutathione administration prevents neuronal cell death following transient brain ischemia2017

    • Author(s)
      Matsuo K, Yabuki Y, Fukunaga K.
    • Journal Title

      Brain Res

      Volume: 1663 Pages: 123-131

    • DOI

      10.1016/j.brainres.2017.03.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-16K14574
  • [Journal Article] Trans-fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway.2017

    • Author(s)
      Hirata, Y., Takahashi, M., Kudoh, Y., Kano, K., Kawana, H., Makide, K., Shinoda, Y., Yabuki, Y., Fukunaga, K., Aoki, J., Noguchi, T., Matsuzawa, A.
    • Journal Title

      J Biol Chem.

      Volume: 印刷中 Pages: 8174-8185

    • DOI

      10.1074/jbc.m116.771519

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01168, KAKENHI-PUBLICLY-15H01391, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-26293011, KAKENHI-PROJECT-15K18856, KAKENHI-PROJECT-16K14574, KAKENHI-PUBLICLY-17H05518, KAKENHI-PROJECT-16K15146
  • [Journal Article] Stress-responsive heme oxygenase-1 isoenzyme participates in Toll-like receptor 4-induced inflammation during brain ischemia.2016

    • Author(s)
      Wang R, Wang ST, Wang YD, Wu G, Du Y, Qian MQ, Liang XG, Elbatreek MH, Yang HY, Liu ZR, Fukunaga K, Liu JX, Lu YM.
    • Journal Title

      Neuroreport.

      Volume: 27 Pages: 445-454

    • DOI

      10.1097/wnr.0000000000000561

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K14574
  • [Journal Article] Valproic acid influences MTNR1A intracellular trafficking and signaling in a β-arrestin 2-dependent manner.2016

    • Author(s)
      Hong LL, Jiang Q, Long S, Wang H, Zhang LD, Tian Y, Wang CK, Cao JJ, Tao RR, Huang JY, Liao MH, Lu YM, Fukunaga K, Zhou NM, Han F.
    • Journal Title

      Molecular Neurobiology

      Volume: 53(2) Pages: 1237-1246

    • DOI

      10.1007/s12035-014-9085-y

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-25293124
  • [Journal Article] Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression2016

    • Author(s)
      Shinoda Y, Tagashira H, Bhuiyan MS, Hasegawa H, Kanai H, Zhang C, Han F, Fukunaga K.
    • Journal Title

      PLoS One

      Volume: 11 Pages: 1-19

    • DOI

      10.1371/journal.pone.0163992

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-14J05570, KAKENHI-PROJECT-26282140, KAKENHI-PROJECT-16K14272, KAKENHI-PROJECT-16K14574, KAKENHI-PROJECT-16K19024
  • [Journal Article] Endogenous Polysialic Acid Based Micelles for Calmodulin Antagonist Delivery against Vascular Dementia.2016

    • Author(s)
      Wang XJ, Gao YP, Lu NN, Li WS, Xu JF, Ying XY, Wu G, Liao MH, Tan C, Shao LX, Lu YM, Zhang C, Fukunaga K, Han F, Du YZ.
    • Journal Title

      ACS Appl Mater Interfaces.

      Volume: 8 Pages: 35045-35058

    • DOI

      10.1021/acsami.6b13052

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K14574
  • [Journal Article] Stimulation of sigma-1 receptor ameliorates depressive-like behaviors via mitochondrial ATP production in CaMKIV null mice2016

    • Author(s)
      Shigeki Moriguchi, Hiroyuki Sakagami, Yasushi Yabuki, Yuzuru Sasaki, Hisanao Izumi, Chen Zhang, Feng Han and Kohji Fukunaga
    • Journal Title

      Folia Pharmacol. Jpn.

      Volume: 52 Issue: 4 Pages: 1210-1222

    • DOI

      10.1254/fpj.147.206

    • NAID

      130005143840

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-16K14574
  • [Journal Article] Functional genomic analyses identify pathways dysregulated in animal model of autism.2016

    • Author(s)
      Huang JY, Tian Y, Wang HJ, Shen H, Wang H, Long S, Liao MH, Liu ZR, Wang ZM, Li D, Tao RR, Cui TT, Moriguchi S, Fukunaga K, Han F, Lu YM.
    • Journal Title

      CNS Neurosci. Ther.

      Volume: 22 Pages: 845-853

    • DOI

      10.1111/cns.12582

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-15K08583, KAKENHI-PROJECT-16K14574
  • [Journal Article] Haloperidol aggravates transverse aortic constriction-induced heart failure via mitochondrial dysfunction.2016

    • Author(s)
      Shinoda Y, Tagashira H, Bhuiyan MS, Hasegawa H, Kanai H, Fukunaga K.
    • Journal Title

      J Pharmacol Sci

      Volume: 131 Pages: 172-183

    • DOI

      10.1016/j.jphs.2016.05.012

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05219, KAKENHI-PROJECT-14J05570, KAKENHI-PROJECT-16K14574, KAKENHI-PROJECT-16K19024
  • [Journal Article] Cognitive function and calcium. cognitive improvement through T type calcium channel stimulation2015

    • Author(s)
      Fukunaga K
    • Journal Title

      Clin Calcium

      Volume: 25 Pages: 247-254

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-26102704
  • [Journal Article] The extracellular fragment of GPNMB (Glycoprotein nonmelanosoma protein B, osteoactivin) improves memory and increases hippocampal GluA1 levels in mice.2015

    • Author(s)
      Murata K., Yoshino Y., Tsuruma K., Moriguchi S., Oyagi A., Tanaka H., Ishisaka M., Shimazawa M., Fukunaga K., Hara H.
    • Journal Title

      J. Neurochem.

      Volume: 132 Pages: 583-594

    • DOI

      10.1111/jnc.13010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J09790, KAKENHI-PROJECT-15K08583
  • [Journal Article] Nuclear Translocation of Calcium/Calmodulin-dependent Protein Kinase IIδ3 Promoted by Protein Phosphatase-1 Enhances Brain-derived Neurotrophic Factor Expression in Dopaminergic Neurons.2015

    • Author(s)
      Shioda N, Sawai M, Ishizuka Y, Shirao T., Fukunaga K
    • Journal Title

      J Biol Chem.

      Volume: 290 Pages: 21663-21675

    • DOI

      10.1074/jbc.m115.664920

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14344, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-25460090, KAKENHI-PROJECT-25293124
  • [Journal Article] berrant Behavioral Sensitization by Methamphetamine in Junctophilin-Deficient Mice.2015

    • Author(s)
      Moriguchi S, Nishi M, Sasaki Y, Takeshima H, Fukunaga K
    • Journal Title

      Molecular Neurobiology

      Volume: 51 Pages: 533-542

    • DOI

      10.1007/s12035-014-8737-2

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
  • [Journal Article] The role of SIGMAR1 gene mutation and mitochondrial dysfunction in amyotrophic lateral sclerosis.2015

    • Author(s)
      Fukunaga K, Shinoda Y, Tagashira H
    • Journal Title

      J Pharmacol Sci.

      Volume: 127 Pages: 36-41

    • DOI

      10.1016/j.jphs.2014.12.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-26893317
  • [Journal Article] Stimulation of sigma-1 receptor ameliorates depressive-like behaviors in CaMKIV null mice.2015

    • Author(s)
      Moriguchi, S.;Sakagami, H.;Yabuki, Y.;Sasaki, Y.;Izumi, H.;Zhang, C.;Han, F.;Fukunaga, K.
    • Journal Title

      Molecular neurobiology

      Volume: 52 Pages: 1210-1222

    • DOI

      10.1007/s12035-014-8923-2

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0003, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-15H04672, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-25293124
  • [Journal Article] Cognitive function and calcium. cognitive improvement through T type calcium channel stimulation2015

    • Author(s)
      Fukunaga K
    • Journal Title

      Clin Calcium

      Volume: 25 Pages: 247-254

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124
  • [Journal Article] Molecular mechanisms of synapse pathology in ATR-X syndrome2015

    • Author(s)
      Shioda N, Fukunaga K.
    • Journal Title

      Folia Pharmacol. Jpn.

      Volume: 145(4) Issue: 4 Pages: 174-177

    • DOI

      10.1254/fpj.145.174

    • NAID

      130005061557

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-25460090, KAKENHI-PROJECT-25293124
  • [Journal Article] Dehydroepiandrosterone administration improves memory deficits following transient brain ischemia through sigma-1 receptor stimulation.2015

    • Author(s)
      Yabuki Y, Shinoda Y, Izumi H, Ikuno T, Shioda N, Fukunaga K.
    • Journal Title

      Brain Res.

      Volume: 1622 Pages: 102-113

    • DOI

      10.1016/j.brainres.2015.05.006

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-15H06036, KAKENHI-PROJECT-25460090, KAKENHI-PROJECT-25293124
  • [Journal Article] Rivastigmine improves hippocampal neurogenesis and depression-like behaviors via 5-HT1A receptor stimulation in olfactory bulbectomized mice.2014

    • Author(s)
      Muhammad Rashedul Islam, Shigeki Moriguchi, Hideaki Tagashira and Kohji Fukunaga
    • Journal Title

      Neuroscience

      Volume: 272 Pages: 116-130

    • DOI

      10.1016/j.neuroscience.2014.04.046

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
  • [Journal Article] Atg5 deficit exaggerates the lysosome formation and cathepsin B activation in mice brain after lipid nanoparticles injection2014

    • Author(s)
      Lu NN, Liu J, Tian Y, Liao MH, Wang H, Lu YM, Tao RR, Hong LJ, Liu SS, Fukunaga K, Du YZ, Han F
    • Journal Title

      Nanomedicine

      Volume: 10 Pages: 1843-1852

    • DOI

      10.1016/j.nano.2014.03.019

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
  • [Journal Article] Aberrant CaMKII activity in the medial prefrontal cortex is associated with cognitive dysfunction in ADHD model rats2014

    • Author(s)
      Yabuki Y, Shioda N, Maeda T, Hiraide S, Togashi H, Fukunaga K.
    • Journal Title

      Brain Res

      Volume: 1557 Pages: 90-100

    • DOI

      10.1016/j.brainres.2014.02.025

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J06540, KAKENHI-PROJECT-23300147, KAKENHI-PROJECT-24659024, KAKENHI-PUBLICLY-25110705, KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25460090, KAKENHI-PUBLICLY-26102704
  • [Journal Article] Targeted therapy of brain ischaemia using Fas ligand antibody conjugated PEG-lipid nanoparticles2014

    • Author(s)
      Lu YM, Huang JY, Wang H, Lou XF, Liao MH, Hong LJ, Tao RR, Ahmed MM, Shan CL, Wang XL, Fukunaga K, Du YZ, Han F
    • Journal Title

      Biomaterials

      Volume: 35 Pages: 530-7

    • DOI

      10.1016/j.biomaterials.2013.09.093

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] FABP3 Protein Promotes α-Synuclein Oligomerization Associated with 1-Methyl-1,2,3,6-tetrahydropiridine-induced Neurotoxicity2014

    • Author(s)
      Shioda N, Yabuki Y, Kobayashi Y, Onozato M, Owada Y, Fukunaga K.
    • Journal Title

      J Mol Histol

      Volume: 289(27) Pages: 18957-18965

    • DOI

      10.1074/jbc.m113.527341

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-14J06540, KAKENHI-PROJECT-24390047, KAKENHI-PUBLICLY-25110705, KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25460090, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-26350122
  • [Journal Article] Peroxiredoxin 1 participates in ischemia-triggered endothelial polarization2014

    • Author(s)
      Ye WF, Tao RR, Jiang Q, Huang JY, Lu NN, Lu YM, Fukunaga K, Wang H, Han F
    • Journal Title

      Neurosci Ther

      Volume: 20 Pages: 791-793

    • DOI

      10.1111/cns.12287

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
  • [Journal Article] Nobiletin treatment improves motor and cognitive deficits seen in MPTP-induced Parkinson model mice2014

    • Author(s)
      Yabuki Y, Ohizumi Y, Yokosuka A, Mimaki Y, Fukunaga K
    • Journal Title

      Neuroscience

      Volume: 259 Pages: 126-141

    • DOI

      10.1016/j.neuroscience.2013.11.051

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] Cardioprotective Effect of the Selective Sigma-1 Receptor Agonist, SA45032014

    • Author(s)
      Hirano K, Tagashira H, Fukunaga K
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 134 Issue: 6 Pages: 707-713

    • DOI

      10.1248/yakushi.13-00255-3

    • NAID

      130004427994

    • ISSN
      0031-6903, 1347-5231
    • Language
      Japanese
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
  • [Journal Article] Diverse Regulation of IP3 and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes2014

    • Author(s)
      Hideaki Tagashira
    • Journal Title

      Life Sci.

      Volume: 305(8) Pages: 89-100

    • DOI

      10.1152/ajpheart.00300.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04360, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PUBLICLY-25110705, KAKENHI-PROJECT-25293124
  • [Journal Article] Aberrant CaMKII activity in the medial prefrontal cortex is associated with cognitive dysfunction in ADHD model rats2014

    • Author(s)
      Yabuki Y, Shioda N, Maeda T, Hiraide S, Togashi H, Fukunaga K
    • Journal Title

      Brain Res

      Volume: 1557 Pages: 90-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147
  • [Journal Article] Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism2014

    • Author(s)
      Tian Y, Yabuki Y, Moriguchi S, Fukunaga K, Mao PJ, Hong LJ, Lu YM, Wang R, Ahmed MM, Liao MH, Huang JY, Zhang RT, Zhou TY, Long S, Han F
    • Journal Title

      J Pineal Res

      Volume: 56(1) Pages: 1-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147
  • [Journal Article] In vivo two-photon fluorescence microscopy reveals disturbed cerebral capillary blood flow and increased susceptibility to ischemic insults in diabetic mice2014

    • Author(s)
      Huang JY, Li LT, Wang H, Liu SS, Lu YM, Liao MH, Tao RR, Hong LJ, Fukunaga K, Chen Z, Wilcox CS, Lai EY, Han F
    • Journal Title

      CNS Neurosci Ther

      Volume: 20 Pages: 816-822

    • DOI

      10.1111/cns.12268

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
  • [Journal Article] Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism.2014

    • Author(s)
      Tian Y, Yabuki Y, Moriguchi S, Fukunaga K, Mao PJ, Hong LJ, Lu YM, Wang R, Ahmed MM, Liao MH, Huang JY, Zhang RT, Zhou TY, Long S, Han F
    • Journal Title

      J Pineal Res

      Volume: 56 Pages: 1-11

    • DOI

      10.1111/jpi.12081

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] CaMKII activity is essential for improvement of memory-related behavior by chronic rivastigmine treatment2014

    • Author(s)
      Shigeki Moriguchi
    • Journal Title

      J Neurochem

      Volume: 128(6) Pages: 927-37

    • DOI

      10.1111/jnc.12510

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-12J04360, KAKENHI-PROJECT-22300114, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25640025
  • [Journal Article] Orphan receptor and chaperon functions of sigma-1 receptor2014

    • Author(s)
      Fukunaga K
    • Journal Title

      Folia Pharmacol. Jpn.

      Volume: 143 Issue: 5 Pages: 263-264

    • DOI

      10.1254/fpj.143.263

    • NAID

      130004827701

    • ISSN
      0015-5691, 1347-8397
    • Language
      Japanese
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
  • [Journal Article] Rivastigmine restores 5-HT1A receptor levels in the hippocampus of olfactory bulbectomized mice2014

    • Author(s)
      Muhammad Rashedul Islam, Shigeki Moriguchi, Hideaki Tagashira and Kohji Fukunaga
    • Journal Title

      Adv Alzheimers Dis

      Volume: 3 Pages: 128-136

    • DOI

      10.4236/aad.2014.33012

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704
  • [Journal Article] Methyl pyruvate rescues mitochondrial damage caused by SIGMAR1 mutation related to amyotrophic lateral sclerosis2014

    • Author(s)
      Tagashira, H., Shinoda, Y., Shioda, N., Fukunaga, K.
    • Journal Title

      Biochim Biophys Acta

      Volume: 1840 Pages: 3320-3334

    • DOI

      10.1016/j.bbagen.2014.08.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-25110705, KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25460090, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-26893317
  • [Journal Article] Fluvoxamine rescues mitochondrial Ca2+ transport and ATP production through σ(1)-receptor in hypertrophic cardiomyocytes2014

    • Author(s)
      Hideaki Tagashira
    • Journal Title

      Life Sci

      Volume: 95(2) Pages: 89-100

    • DOI

      10.1016/j.lfs.2013.12.019

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-12J04360, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25460090
  • [Journal Article] Ultrasonic visualization of propagation of myocardial vibration driven by electrical excitation of myocardium of rat in ex vivo experiment2014

    • Author(s)
      Fujita Y, Tagashira H, Hasegawa H, Fukunaga K, Kanai H
    • Journal Title

      Jpn. J. Appl. Phys.

      Volume: 53 Issue: 7S Pages: 07KF25-07KF25

    • DOI

      10.7567/jjap.53.07kf25

    • NAID

      210000144276

    • ISSN
      0021-4922, 1347-4065
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25630165, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-26289123
  • [Journal Article] Nitrosative stress induces peroxiredoxin 1 ubiquitination during ischemic insult via E6AP activation in endothelial cells both in vitro and in vivo.2014

    • Author(s)
      Tao RR, Wang H, Hong LJ, Huang JY, Lu YM, Liao MH, Ye WF, Lu NN, Zhu DY, Huang Q, Fukunaga K, Lou YJ, Shoji I, Wilcox CS, Lai EY, Han F
    • Journal Title

      Antioxid Redox Signal

      Volume: (in press) Pages: 1-16

    • DOI

      10.1089/ars.2013.5381

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-26102704, KAKENHI-PROJECT-26461003
  • [Journal Article] Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells : a potential vasoprotective effect of melatonin2013

    • Author(s)
      Tao RR, Huang JY, Shao XJ, Ye WF, Tian Y, Liao MH, Fukunaga K, Lou YJ, Han F, Lu YM.
    • Journal Title

      J Pineal Res

      Volume: 54(3) Pages: 271-281

    • DOI

      10.1111/jpi.12009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-24102505
  • [Journal Article] Crucial Interactions Between Selective Serotonin Uptake Inhibitors and Sigma-1 Receptor in Heart Failure2013

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 121 Issue: 3 Pages: 177-184

    • DOI

      10.1254/jphs.12r13cp

      10.1254/jphs.12R13CP

    • NAID

      10031165462

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] Novel nootropic drug sunifiram enhances hippocampal synaptic efficact via glycine-binding site of N-methyl-D-aspartate receptor2013

    • Author(s)
      Moriguchi S, Tanaka T, Narahashi T, Fukunaga K
    • Journal Title

      Hippocampus

      Volume: 23 Pages: 942-51

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293124
  • [Journal Article] The effect of lipid nanoparticle PEGylation on neuroinflammatory response in mouse brain2013

    • Author(s)
      Huang JY, Lu YM, Wang H, Liu J, Liao MH, Hong LJ, Tao RR, Ahmed MM, Liu P, Liu SS, Fukunaga K, Du YZ, Han F
    • Journal Title

      Biomaterials

      Volume: 34 Pages: 7960-70

    • DOI

      10.1016/j.biomaterials.2013.07.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation.2013

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K.
    • Journal Title

      J Pharmacol Sci.

      Volume: 121 Pages: 212-226

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505
  • [Journal Article] Stimulation of σ1-receptor restores abnormal mitochondrial Ca(2+) mobilization and ATP production following cardiac hypertrophy.2013

    • Author(s)
      Hideaki Tagashira
    • Journal Title

      Biochim Biophys Acta

      Volume: 1830(4) Pages: 3082-3094

    • DOI

      10.1016/j.bbagen.2012.12.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04360, KAKENHI-PROJECT-22390109, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] Decreased CaMKII and PKC activities in specific brain regions are associated with cognitive impairment in neonatal ventral hippocampus-lesioned rats2013

    • Author(s)
      Yabuki Y, Nakagawasai O, Moriguchi S, Shioda N, Onogi H, Tan-No K, Tadano T, Fukunaga K
    • Journal Title

      Neuroscience

      Volume: 234 Pages: 103-115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147
  • [Journal Article] The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation.2013

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K.
    • Journal Title

      J Pharmacol Sci.

      Volume: 121(3) Pages: 212-226

    • NAID

      10031165466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659024
  • [Journal Article] The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation2013

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 121 Issue: 3 Pages: 212-226

    • DOI

      10.1254/jphs.12233fp

      10.1254/jphs.12233FP

    • NAID

      10031165466

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293124
  • [Journal Article] Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice2013

    • Author(s)
      Shigeki Moriguchi
    • Journal Title

      PLoS One

      Volume: 8(4)

    • DOI

      10.1371/journal.pone.0060863

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04360, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-24890144, KAKENHI-PROJECT-25293124
  • [Journal Article] Crucial interactions between selective serotonin uptake inhibitors and sigma-1 receptor in heart failure.2013

    • Author(s)
      Bhuiyan S, Tagashira H, Fukunaga K.
    • Journal Title

      J Pharmacol Sci.

      Volume: 121(3) Pages: 177-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice2013

    • Author(s)
      Moriguchi S, Tanaka T, Tagashira H, Narahashi T, Fukunaga K.
    • Journal Title

      Behav Brain Res

      Volume: 242 Pages: 150-157

    • DOI

      10.1016/j.bbr.2012.12.054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-24102505
  • [Journal Article] The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation2013

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      J Pharmacol Sci

      Volume: 121(3) Pages: 212-26

    • NAID

      10031165466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659024
  • [Journal Article] Decreased CaMKII and PKC activities in specific brain regions are associated with cognitive impairment in neonatal ventral hippocampus-lesioned rats2013

    • Author(s)
      Yabuki Y, Nakagawasai O, Moriguchi S, Shioda N, Onogi H, Tan-No K, Tadano T, Fukunaga K.
    • Journal Title

      Neuroscience.

      Volume: 234 Pages: 103-115

    • DOI

      10.1016/j.neuroscience.2012.12.048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790072, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PUBLICLY-25110705, KAKENHI-PROJECT-25293124, KAKENHI-PROJECT-25460090, KAKENHI-PUBLICLY-23110501
  • [Journal Article] Vascular Endothelial &sigma;<sub>1</sub>-Receptor Stimulation With SA4503 Rescues Aortic Relaxation via Akt/eNOS Signaling in Ovariectomized Rats With Aortic Banding2013

    • Author(s)
      Tagashira H, Matsumoto T, Taguchi K, Zhang C, Han F, Ishida K, Nemoto S, Kobayashi T, Fukunaga K
    • Journal Title

      Circulation Journal

      Volume: 77 Issue: 11 Pages: 2831-2840

    • DOI

      10.1253/circj.cj-13-0256

      10.1253/circj.CJ-13-0256

    • NAID

      10031196838

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] The Disturbance of Hippocampal CaMKII/PKA/PKC Phosphorylation in Early Experimental Diabetes Mellitus2013

    • Author(s)
      Liao MH, Xiang YC, Huang JY, Tao RR, Tian Y, Ye WF, Zhang GS, Lu YM, Ahmed MM, Liu ZR, Fukunaga K, Han F.
    • Journal Title

      CNS Neurosci Ther

      Volume: - Pages: 329-36

    • DOI

      10.1111/cns.12084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-24102505
  • [Journal Article] A novel cognitive enhancer, ST101, enhances acetylcholine release in mouse dorsal hippocampus through T-type voltage-gated calcium channel stimulation2013

    • Author(s)
      Yui Yamamoto, Norifumi Shioda, Feng Han, Shigeki Moriguchi and Kohji Fukunaga
    • Journal Title

      J. Pharmacol. Sci.

      Volume: 121 Pages: 212-226

    • NAID

      10031165466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590653
  • [Journal Article] Imaging Monitoring Method of CaMKII Activity by Immunohistochemical Analysis in Schizophrenic Model Rats2013

    • Author(s)
      Yabuki Y, Nakagawasai O, Tadano T, Fukunaga K
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 133 Issue: 5 Pages: 501-506

    • DOI

      10.1248/yakushi.12-00278-3

    • NAID

      130003361942

    • ISSN
      0031-6903, 1347-5231
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] Interaction of PICK1 with C-Terminus of Growth Hormone–Releasing Hormone Receptor (GHRHR) Modulates Trafficking and Signal Transduction of Human GHRHR2013

    • Author(s)
      Katsushima Y, Sato T., Yamada C., Ito M., Suzuki Y., Ogawa E., Sukegawa I., Sukegawa J., Fukunaga K., Yanagisawa T.
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 122 Issue: 3 Pages: 193-204

    • DOI

      10.1254/jphs.12287fp

      10.1254/jphs.12287FP

    • NAID

      10031185413

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23618003, KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590311, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] Stimulation of the sigma-1 receptor by DHEA enhances synaptic efficacy and neurogenesis in the hippocampal dentate gyrus of olfactory bulbectomized mice.2013

    • Author(s)
      Shigeki Moriguchi, Yasuharu Shinoda, Yui Yamamoto, Yuzuru Sasaki, Kosuke Miyajima, Hideaki Tagashira and Kohji Fukunaga
    • Journal Title

      PLoS One

      Volume: 8

    • DOI

      10.1371/annotation/9fdc3705-7112-4382-a3a2-dcde33229272

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590653
  • [Journal Article] The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation.2013

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K.
    • Journal Title

      J Pharmacol Sci.

      Volume: 121(3) Pages: 212-226

    • NAID

      10031165466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Theγ-secretase blocker DAPT reduces the permeability of the blood-brain barrier by decreasing the ubiquitination and degradation of occludin during permanent brain ischemia2013

    • Author(s)
      Zhang GS, Tian Y, Huang JY, Tao RR, Liao MH, Lu YM, Ye WF, Wang R, Fukunaga K, Lou YJ, Han F.
    • Journal Title

      CNS Neurosci Ther

      Volume: 19(1) Pages: 53-60

    • DOI

      10.1111/cns.12032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-24102505
  • [Journal Article] Crucial interactions between selective serotonin uptake inhibitors and sigma-1 receptor in heart failure.2013

    • Author(s)
      Bhuiyan S, Tagashira H, Fukunaga K. Crucial interactions between selective serotonin uptake inhibitors and sigma-1 receptor in heart failure.
    • Journal Title

      J Pharmacol Sci.

      Volume: 121 Pages: 177-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505
  • [Journal Article] Oral L-citrulline administration improves memory deficits following transient brain ischemia through cerebrovascular protection.2013

    • Author(s)
      Yabuki Y, Shioda N, Yamamoto Y, Shigano M, Kumagai K, Morita M, Fukunaga K.
    • Journal Title

      Brain Res.

      Volume: 1520 Pages: 157-167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460090
  • [Journal Article] Influence of Maternal Exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Socioemotional Behaviors in Offspring Rats.2013

    • Author(s)
      Nguyen AT, Nishijo M, Hori E, Nguyen NM, Pham TT, Fukunaga K, Nakagawa H, Tran AH, Nishijo H.
    • Journal Title

      Environ Health Insights.

      Volume: 7 Pages: 1-14

    • DOI

      10.4137/ehi.s10346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22240051, KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124, KAKENHI-PUBLICLY-24102505
  • [Journal Article] Crucial interactions between selective serotonin uptake inhibitors and sigma-1 receptor in heart failure.2013

    • Author(s)
      Bhuiyan S, Tagashira H, Fukunaga K.
    • Journal Title

      J Pharmacol Sci.

      Volume: 121(3) Pages: 177-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659024
  • [Journal Article] Oral L-citrulline administration improves memory deficits following transient brain ischemia through cerebrovascular protection.2013

    • Author(s)
      Yabuki Y, Shioda N, Yamamoto Y, Shigano M, Kumagai K, Morita M, Fukunaga K
    • Journal Title

      Brain Research

      Volume: 1520 Pages: 157-167

    • DOI

      10.1016/j.brainres.2013.05.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-24890144, KAKENHI-PROJECT-25293124
  • [Journal Article] Interaction of PICK1 with C-terminus of growth hormone-releasing hormone receptor (GHRHR) modulates trafficking and signal transduction of human GHRHR2013

    • Author(s)
      Katsushima Y, Sato T, Yamada C, Ito M, Suzuki Y, Ogawa E, Sukegawa I, Sukegawa J, Fukunaga K, Yanagisawa T
    • Journal Title

      J Pharmacol Sci

      Volume: 122(3) Pages: 193-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147
  • [Journal Article] Oral administration of glutathione improves memory deficits following transient brain ishemia by reducing brain oxidative stress2013

    • Author(s)
      Yabuki Y, Fukunaga K
    • Journal Title

      Neuroscience

      Volume: 250 Pages: 394-407

    • DOI

      10.1016/j.neuroscience.2013.07.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] Nobiletin induces inhibitions of Ras activity and mitogen-activated protein kinase/extracellular signal-regulated kinase signaling to suppress cell proliferation in C6 rat glioma cells2013

    • Author(s)
      Moriguchi S, Tanaka T, Narahashi T, Fukunaga K
    • Journal Title

      Biol Pharm Bull

      Volume: 23 Pages: 942-51

    • DOI

      10.1002/hipo.22150

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PROJECT-25293124
  • [Journal Article] Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice2012

    • Author(s)
      Moriguchi S, Yabuki Y, Fukunaga K.
    • Journal Title

      J Neurochem

      Volume: 120 Pages: 541-551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Aberrant hippocampalspine morphology and impaired memory formation in neuronal platelet-derived growth factor beta-receptor lacking mice2012

    • Author(s)
      Shioda N, Moriguchi S, Oya T, Ishii T, Shen J, Matsushima T, Nishijo H, Sasahara M, Fukunaga K.
    • Journal Title

      J Neurochem.

      Volume: 22(6) Pages: 1371-1378

    • DOI

      10.1002/hipo.20973

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22240051, KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-22659012, KAKENHI-PUBLICLY-23110501, KAKENHI-PROJECT-23300147, KAKENHI-PROJECT-23590444, KAKENHI-PROJECT-23790072, KAKENHI-PROJECT-24590653
  • [Journal Article] Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites.2012

    • Author(s)
      Shinoda Y, Fujita K, Saito S, Matsui H, Kanto Y, Nagaura Y, Fukunaga K, Tamura S, Kobayashi T.
    • Journal Title

      FEBS Lett.

      Volume: 586 Pages: 3024-3029

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505
  • [Journal Article] Reduced caicium/calmodulin-dependent protein kiaase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice2012

    • Author(s)
      Moriguchi S, Yabuki Y, Fukunaga K
    • Journal Title

      J.Neurochem.

      Volume: 120 Pages: 541-551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist.2012

    • Author(s)
      Tagashira H, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi.

      Volume: 132(2) Pages: 167-172

    • NAID

      130001872003

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505
  • [Journal Article] The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101: enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices2012

    • Author(s)
      Shigeki Moriguchi
    • Journal Title

      J. Neurochem.

      Volume: 121(1) Pages: 44-53

    • DOI

      10.1111/j.1471-4159.2012.07667.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04360, KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-23790072, KAKENHI-PROJECT-24590653, KAKENHI-PROJECT-24659024, KAKENHI-PUBLICLY-23110501, KAKENHI-PUBLICLY-24102505
  • [Journal Article] P2X(7) signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand.2012

    • Author(s)
      Lu YM, Tao RR, Huang JY, Li LT, Liao MH, Li XM, Fukunaga K, Hong ZH, Han F
    • Journal Title

      J Neuroinflammation.

      Volume: 9 Pages: 172-172

    • DOI

      10.1186/1742-2094-9-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24659024, KAKENHI-PUBLICLY-24102505
  • [Journal Article] Benefit of vanadium compound in therapy for cardiovascular diseases.2012

    • Author(s)
      Fukunaga K.
    • Journal Title

      Yakugaku Zasshi.

      Volume: 132 Pages: 279-284

    • NAID

      130001872021

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24102505
  • [Journal Article] Novel dopamine D2 receptor signaling through proteins interacting with the third cytoplasmic loop2012

    • Author(s)
      Fukunaga K, Shioda N
    • Journal Title

      Mol Neurobiol

      Volume: 45(1) Pages: 144-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist.2012

    • Author(s)
      Tagashira H, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi.

      Volume: 132(2) Pages: 167-172

    • NAID

      130001872003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice.2012

    • Author(s)
      Moriguchi S, Yabuki Y, Fukunaga K
    • Journal Title

      J. Neurochem.

      Volume: 120(4) Pages: 541-51

    • DOI

      10.1111/j.1471-4159.2011.07608.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-24590653
  • [Journal Article] Benefit of vanadium compound in therapy for cardiovascular diseases.2012

    • Author(s)
      Fukunaga K.
    • Journal Title

      Yakugaku Zasshi.

      Volume: 132 Pages: 279-284

    • NAID

      130001872021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659024
  • [Journal Article] Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites2012

    • Author(s)
      Shinoda Y, Fujita K, Saito S, Matsui H, Kanto Y, Nagaura Y, Fukunaga K, Tamura S, Kobayashi T
    • Journal Title

      FEBS Lett

      Volume: 586(19) Pages: 3024-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Benefit of vanadium compound in therapy for cardiovascular diseases2012

    • Author(s)
      Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 132 Pages: 279-284

    • NAID

      130001872021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites.2012

    • Author(s)
      Shinoda Y, Fujita K, Saito S, Matsui H, Kanto Y, Nagaura Y, Fukunaga K, Tamura S, Kobayashi T.
    • Journal Title

      FEBS Lett.

      Volume: 586(19) Pages: 3024-3029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Novel dopamine D2 receptor signaling through proteins interacting with the third cytoplasmic loop2012

    • Author(s)
      Fukunaga K, Shioda N.
    • Journal Title

      Mol Neurobiol

      Volume: 45 Pages: 144-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist.2012

    • Author(s)
      Tagashira H, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi.

      Volume: 132 Pages: 167-172

    • NAID

      130001872003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659024
  • [Journal Article] Abnormal dendritic spine morphology and its signal transduction mechanisms in mental retardation2012

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Seikagaku

      Volume: 83(12) Pages: 1113-1117

    • NAID

      10030345941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147
  • [Journal Article] Benefit of vanadium compound in therapy for cardiovascular diseases2012

    • Author(s)
      Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 132(3) Pages: 279-84

    • NAID

      130001872021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Aberrant hippocampal spine morphology and impaired memory formation in neuronal platelet-derived growth factor beta-receptor lacking mice2012

    • Author(s)
      Shioda N, Moriguchi S, Oya T, Ishii Y, Shen J, Matsushima T, Nishijo H, Sasahara M, Fukunaga K.
    • Journal Title

      Hippocampus

      Volume: 22 Pages: 1371-1378

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Targeting nitrosative stress for neurovascular protection : new implications in brain diseases2012

    • Author(s)
      Tao RR, Ji YL, Lu YM, Fukunaga K, Han F.
    • Journal Title

      Curr Drug Targets

      Volume: 13 Pages: 272-284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101 : enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices2012

    • Author(s)
      Moriguchi S, Shioda N, Yamamoto Y, Tagashira H, Fukunaga K
    • Journal Title

      J Neurochem

      Volume: 121 Pages: 44-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Novel dopamine D2 receptor signaling through proteins interacting with the third cytoplasmic loop2012

    • Author(s)
      Fukunaga K, Shioda N
    • Journal Title

      Mol Neurobiol

      Volume: 45(1) Pages: 144-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147
  • [Journal Article] Abnormal dendritic spine morphology and its signal transduction mechanisms in mental retardation2012

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Seikagaku

      Volume: 83(12) Pages: 1113-7

    • NAID

      10030345941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist2012

    • Author(s)
      Tagashira H, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 132 Pages: 167-172

    • NAID

      130001872003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101 : enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices2012

    • Author(s)
      Moriguchi S, Shioda N, Yamamoto Y, Tagashira H, Fukunaga K
    • Journal Title

      J Neurochem.

      Volume: 121 Pages: 44-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Benefit of vanadium compound in therapy for cardiovascular diseases.2012

    • Author(s)
      Fukunaga K.
    • Journal Title

      Yakugaku Zasshi.

      Volume: 132(3) Pages: 279-284

    • NAID

      130001872021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Benefit of vanadium compound in therapy for cardiovascular diseases2012

    • Author(s)
      Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 132 Pages: 279-284

    • NAID

      130001872021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites2012

    • Author(s)
      Shinoda Y, Fujita K, Saito S, Matsui H, Kanto Y, Nagaura Y, Fukunaga K, Tamura S, Kobayashi T
    • Journal Title

      FEBS Lett

      Volume: 586(19) Pages: 3024-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659024
  • [Journal Article] Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist2012

    • Author(s)
      Tagashira H, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 132 Pages: 167-172

    • NAID

      130001872003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Expression of a truncated form of the endoplasmic reticulum chaperone protein, sigma-1 receptor, promotes mitochondrial energy depletion and apoptosis2012

    • Author(s)
      Norifumi Shioda
    • Journal Title

      J Biol Chem

      Volume: 287(28) Pages: 23318-23331

    • DOI

      10.1074/jbc.m112.349142

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04360, KAKENHI-PROJECT-20390108, KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-23790072, KAKENHI-PROJECT-24659024, KAKENHI-PUBLICLY-23110501, KAKENHI-PUBLICLY-24102505
  • [Journal Article] Cardioprotective effect of fluvoxamine, sigma-1 receptor high affinity agonist2012

    • Author(s)
      Tagashira H, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 132(2) Pages: 167-72

    • NAID

      130001872003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice2012

    • Author(s)
      Moriguchi S, Yabuki Y, Fukunaga K
    • Journal Title

      J.Neurochem.

      Volume: 120 Pages: 541-551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Acyl-CoA binding domain containing 3 (ACBD3) recruits the protein phosphatase PPM1L to ER-Golgi membrane contact sites.2012

    • Author(s)
      Shinoda Y, Fujita K, Saito S, Matsui H, Kanto Y, Nagaura Y, Fukunaga K, Tamura S, Kobayashi T.
    • Journal Title

      FEBS Lett.

      Volume: 586(19) Pages: 3024-3029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659024
  • [Journal Article] Novel dopamine D2 receptor signaling through proteins interacting with the third cytoplasmic loop2012

    • Author(s)
      Fukunaga K, Shioda N
    • Journal Title

      Mol Neurobiol.

      Volume: 45 Pages: 144-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Novel dopamine D2 receptor signaling through proteins interacting with the third cytoplasmic loop2012

    • Author(s)
      Fukunaga K, Shioda N
    • Journal Title

      Mol Neurobiol

      Volume: 45 Pages: 144-152

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Aberrant catcium/cahnodu lin-dependent protein kinase II(CaMKII)activity is associated with abnormal dendritic spine morphology in the A TRX mutant mouse brain.2011

    • Author(s)
      Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K
    • Journal Title

      J Neurosci.

      Volume: 31 Pages: 346-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Functional roles of constitutively active calcineurin in delayed neuronal death after brain ischemia2011

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 13-20

    • NAID

      130000451520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardio protection.2011

    • Author(s)
      Moriguchi S, Oomura Y, ShiodaN, Han F, Hori N, Aou S, Fukunaga K
    • Journal Title

      Mol Cell Neurosci.

      Volume: 46 Pages: 101-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding2011

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K.
    • Journal Title

      Eur J. Pharmacol

      Volume: 650 Pages: 621-628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011

    • Author(s)
      Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H
    • Journal Title

      Brain Res.

      Volume: 24 Pages: 97-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Distinct cardioprotective effects of 17beta-estradiol and dehydroepiandrosterone on pressure overload-induced hypertrophy in ovariectomized female rats2011

    • Author(s)
      Tagashira H, Bhuiyan MS, Shioda N, Fukunaga K
    • Journal Title

      Menopause

      Volume: 18(12) Pages: 1317-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice.2011

    • Author(s)
      Nogami T, Beppu H, Tokoro T Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sa Sahara M, Shimada Y, NishijoH, Li E, Kitajima I
    • Journal Title

      Hippocampus.

      Volume: 印刷中(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] CaMKIIδB mediates aberrant NCX1 expression and the imbalance of NCX1/SERCA in transverse aortic constriction-induced failing heart2011

    • Author(s)
      Lu YM, Huang J, Shioda N, Fukunaga K, Shirasaki Y, Li XM, Han F.
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding2011

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K
    • Journal Title

      Eur.J.Pharmacol.

      Volume: 650 Pages: 621-628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice2011

    • Author(s)
      Nogami T, Beppu H, Tokoro T, Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sasahara M, Shimada Y, Nishijo H, Li E, Kitajima I.
    • Journal Title

      Hippocampus

      Volume: 21 Pages: 678-687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Functional roles of constitutively active calcineurin in delayed neuronal death after brain ischemia2011

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 131 Pages: 13-20

    • NAID

      130000451520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Regulation of dopaminergic neuronal activity by heart-type fetty acid binding protein in the brain2011

    • Author(s)
      Yamamoto Y, Shioda N, Owada Y, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 131 Pages: 497-501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Melatonin ameliorates ischemic-like injury-evoked nitrosative stress: Involvement of HtrA2/PED pathways in endothelial cells2011

    • Author(s)
      Han F, Tao RR, Zhang GS, Lu YM, Liu LL, Chen YX, Lou YJ, Fukunaga K, Hong ZH
    • Journal Title

      J Pineal Res

      Volume: 50 Pages: 281-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection2011

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Expert Opin.Ther.Targets.

      Volume: 15 Pages: 145-155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Dehydroepiandrosterone-mediated stimulation of sigma-1 receptor activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding2011

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K.
    • Journal Title

      Cardiovasc Ther

      Volume: 29(4) Pages: 219-30

    • DOI

      10.1111/j.1755-5922.2010.00196.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Distinct cardioprotective effects of 17ss-estradiol and dehydroepiandroster one on pressure overload-induced hyertrophy in ovariectomized female rats2011

    • Author(s)
      Tagashira H, Bhuiyan S, Shioda N, Fukunaga K
    • Journal Title

      Menopause

      Volume: 18 Pages: 1317-1326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Regulation of Dopaminergic Neuronal Activity by Heart-type Fatty Acid Binding Protein in the Brain.2011

    • Author(s)
      Yamamoto Y, Shioda N, Owada Y, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 497-501

    • NAID

      130000678828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection2011

    • Author(s)
      Bhuiyan MS, Fukunaga K.
    • Journal Title

      Expert Opin Ther Targets

      Volume: 15(2) Pages: 145-155

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21204730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Aberrant calcium/calmodulin-dependent protein kinase II(CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain2011

    • Author(s)
      Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K.
    • Journal Title

      J Neurosci Res

      Volume: 31 Pages: 346-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice.2011

    • Author(s)
      Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K.
    • Journal Title

      J Neurochem.

      Volume: 印刷中(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain2011

    • Author(s)
      Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K
    • Journal Title

      J Neurosci

      Volume: 31 Pages: 346-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII)activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain2011

    • Author(s)
      Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K.
    • Journal Title

      J Neurosci

      Volume: 31(1) Pages: 346-58

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21209221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) aciivity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain.2011

    • Author(s)
      Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K
    • Journal Title

      J Neurosci.

      Volume: 31 Pages: 346-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Establishment of "evidence based medicine" for the treatment of cerebral stroke-bridging basic and clinical sciences2011

    • Author(s)
      Tokuyama S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 131 Pages: 503-504

    • NAID

      130000678829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior2011

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi

      Volume: 131(4) Pages: 505-11

    • NAID

      130000678830

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21467789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] CaMKIIδB Mediates Aberrant NCX1 Expression and the Imbalance of NCX1/SERCA in Transverse Aortic Constriction-Induced Failing Heart2011

    • Author(s)
      Lu YM, Huang J, Shioda N, Fukunaga K, Shirasaki Y, Li XM, Han F
    • Journal Title

      PLoS One.

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Establishment of "evidence based medicine" for the treatment of cerebral stroke--bridging basic and clinical sciences2011

    • Author(s)
      Tokuyama S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 503-504

    • NAID

      130000678829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Dopamine D2 receptor as a novel target molecule for heart-type fatty acid binding protein2011

    • Author(s)
      Shioda N, Yamamoto Y, Owada Y, Fukunaga K
    • Journal Title

      Nihon Shinkei Seishin Yakurigaku Zasshi.

      Volume: 31 Pages: 125-130

    • NAID

      10029094334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice.2011

    • Author(s)
      Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K.
    • Journal Title

      J Neurochem.

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding.2011

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K
    • Journal Title

      Eur J Pharmacol.

      Volume: 650 Pages: 621-628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardio protection2011

    • Author(s)
      Bhuiyan MS, Fukunaga K.
    • Journal Title

      Expert Opin Ther Targets.

      Volume: 印刷中(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Distinct cardioprotective effects of 17β-estradiol and dehydroepiandrosterone on pressure overload induced hypertrophy in ovariectomized female rats2011

    • Author(s)
      Tagashira H, Bhuiyan S, Shioda N, Fukunaga K.
    • Journal Title

      Menopause

      Volume: 18(12) Pages: 1317-26

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21844826

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011

    • Author(s)
      Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K
    • Journal Title

      J.Neurochem.

      Volume: 117 Pages: 879-891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Ca2+/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011

    • Author(s)
      Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K.
    • Journal Title

      Mol Cell Neurosci

      Volume: 46(1) Pages: 101-7

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20807573

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Dopamine D2 receptor as a novel target molecule for heart-type fatty acid binding protein2011

    • Author(s)
      Shioda N, Yamamoto Y, Owada Y, Fukunaga K
    • Journal Title

      Nihon Shinkei Seishin Yakurigaku Zasshi

      Volume: 31(3) Pages: 125-30

    • NAID

      10029094334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior2011

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 505-511

    • NAID

      130000678830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Melatonin ameliorates ischemic-like injury-evoked nitrosative stress : Involvement of HtrA2/PED pathways in endothelial cells2011

    • Author(s)
      Han F, Tao RR, Zhang GS, Lu YM, Liu LL, Chen YX, Lou YJ, Fukunaga K, Hong ZH.
    • Journal Title

      J Pineal Res

      Volume: 50 Pages: 281-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] CaMKIIδB mediates aberrant NCX1 expression and the imbalance of NCX1/SERCA in transverse aortic constriction-induced failing heart2011

    • Author(s)
      Lu YM, Huang J, Shioda N, Fukunaga K, Shirasaki Y, Li XM, Han F.
    • Journal Title

      PLoS One

      Volume: 6(9)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21931829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Regulation of Dopaminergic Neuronal Activity by Heart-type Fatty Acid Binding.Protein in the Brain.2011

    • Author(s)
      Yamamoto Y, Shioda N, OwadaY, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 497-501

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Expression profiling of Ca(2+)/calmodulin-dependent signaling molecules in the rat dorsal and ventral hippocampus after acute lead exposure.2011

    • Author(s)
      Zhang GS, Ye WF, Tao RR, LuYM, Shen GF, Fukunaga K, Huang JY, Ji YL, Han F
    • Journal Title

      Exp Toxicol Pathol.

      Volume: 印刷中(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice2011

    • Author(s)
      Nogami T1, Beppu H, Tokoro T, Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sasahara M, Shimada Y, Nishijo H, Li E, Kitajima I
    • Journal Title

      Hippocampus

      Volume: 21(6) Pages: 678-687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147
  • [Journal Article] Targeting nitrosative stress for neurovascular protection : New implications in brain diseases2011

    • Author(s)
      Tao RR, Ji YL, Lu YM, Fukunaga K, Han F
    • Journal Title

      Curr.Drug Targets.

      Volume: 13 Pages: 272-284

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Functional roles of constitutively active calcineurin in delayed neuronal death after brain ischemia2011

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 131 Pages: 13-20

    • NAID

      130000451520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells2011

    • Author(s)
      Han F, Chen YX, Lu YM, Huang JY, Zhang GS, Tao RR, Ji YL, Liao MH, Fukunaga K, Qin ZH
    • Journal Title

      J Pineal Res

      Volume: 51(1) Pages: 124-35

    • DOI

      10.1111/j.1600-079x.2011.00869.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-22659012
  • [Journal Article] Melatonin ameliorates ischemic-like injury-evoked nitrosative stress : Involvement of HtrA2/PED pathways in endothelial cells2011

    • Author(s)
      Han F, Tao RR, Zhang GS, Lu YM, Liu LL, Chen YX, Lou YJ, Fukunaga K, Hong ZH
    • Journal Title

      J Pineal Res

      Volume: 50(3) Pages: 281-91

    • DOI

      10.1111/j.1600-079x.2010.00838.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Regulation of dopaminergic neuronal activity by heart-type fatty acid binding protein in the brain2011

    • Author(s)
      Yamamoto Y, Shioda N, Owada Y, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 497-501

    • NAID

      130000678828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection2011

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Expert Opin Ther Targets

      Volume: 15 Pages: 145-155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] CaMK IIδB mediates aberrant NCX1 expression and the imbalance of NCX1/SERCA in transverse aortic constriction-induced failing heart2011

    • Author(s)
      Lu YM, Huang J, Shioda N, Fukunaga K, Shirasaki Y, Li XM, Han F
    • Journal Title

      PLos One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior.2011

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 505-511

    • NAID

      130000678830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain2011

    • Author(s)
      Shioda N1, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K
    • Journal Title

      J Neurosci

      Volume: 31(1) Pages: 346-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23300147
  • [Journal Article] Ca(2+)/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011

    • Author(s)
      Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K
    • Journal Title

      Mol Cell Neurosci

      Volume: 46 Pages: 101-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Dehydroepiandrosterone-Mediated Stimulation of Sigma-1 Receptor Activates Akt-eNOS Signaling in the Thoracic Aorta of Ovariectomized Rats with Abdominal Aortic Banding.2011

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K
    • Journal Title

      Cardiavasc Ther.

      Volume: 印刷中(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells.2011

    • Author(s)
      Han F, Chen YX, Lu YM, Huang JY, Zhang GS, Tao RR, Ji YL, Liao MH, Fukunaga K, Qin ZH.
    • Journal Title

      J Pineal Res.

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Drug Development Targeting for Tyrosine Phosphatase2011

    • Author(s)
      Fukunaga K
    • Journal Title

      Cell Technology

      Volume: 30 Pages: 631-636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] The establishment of"evidence based medicine"for the treatment of cerebral stroke-bridging basic and clinical sciences2011

    • Author(s)
      Tokuyama S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 503-504

    • NAID

      130000678829

    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011

    • Author(s)
      Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H.
    • Journal Title

      Brain Res

      Volume: 1419 Pages: 97-104

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21945083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011

    • Author(s)
      Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K.
    • Journal Title

      J Neurochem

      Volume: 117 Pages: 879-891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Drug Development Targeting for Tyrosine Phosphatase2011

    • Author(s)
      Fukunaga K
    • Journal Title

      Cell Technology

      Volume: 30 Pages: 631-636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Ca(2+)/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011

    • Author(s)
      Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K
    • Journal Title

      Mol.Cell Neurosci.

      Volume: 46 Pages: 101-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011

    • Author(s)
      Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H
    • Journal Title

      Brain Res

      Volume: 1419 Pages: 97-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice2011

    • Author(s)
      Nogami T.
    • Journal Title

      Hippocampus

      Volume: 21 Pages: 678-687

    • DOI

      10.1002/hipo.20782

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108, KAKENHI-PROJECT-22659012
  • [Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior.2011

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 505-511

    • NAID

      130000678830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding2011

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K.
    • Journal Title

      Eur J Pharmacol

      Volume: 650(2-3) Pages: 621-8

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21044620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011

    • Author(s)
      Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K
    • Journal Title

      J.Neurochem.

      Volume: 117 Pages: 879-891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain2011

    • Author(s)
      Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K
    • Journal Title

      J.Neurosci.

      Volume: 31 Pages: 346-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Regulation of Dopaminergic Neuronal Activity by Heart-type Fatty Acid Binding Protein in the Brain2011

    • Author(s)
      Yamamoto Y, Shioda N, Owada Y, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 131 Pages: 497-501

    • NAID

      130000678828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells2011

    • Author(s)
      Han F, Chen YX, Lu YM, Huang JY, Zhang GS, Tao RR, Ji YL, Liao MH, Fukunaga K, Qin ZH
    • Journal Title

      J.Pineal.Res.

      Volume: 51 Pages: 124-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding.2011

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K
    • Journal Title

      Eur J Pharmacol.

      Volume: 650 Pages: 621-628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardio protection.2011

    • Author(s)
      Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K
    • Journal Title

      Mol Cell Neurosci.

      Volume: 46 Pages: 101-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Distinct cardioprotective effects of 17β-estradiol and dehydroepiandrosterone on pressure overload-induced hypertrophy in ovariectomized female rats2011

    • Author(s)
      Tagashira H, Bhuiyan S, Shioda N, Fukunaga K
    • Journal Title

      Menopause.

      Volume: 18 Pages: 1317-1326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice2011

    • Author(s)
      Nogami T, Beppu H, Tokoro T, Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sasahara M, Shimada Y, Nishijo H, Li E, Kitajima I
    • Journal Title

      Hippocampus

      Volume: 21 Pages: 678-687

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Expression profiling of Ca(2+)/calmodulin-dependent signaling molecues in the rat dorsal and ventral hippocampus after acute lead exposuie.2011

    • Author(s)
      Zhang GS, Ye WF, Tao RR, Lu YM, Shen GF, Fukunaga K, Huang JY, Ji YL, Han F
    • Journal Title

      Exp Toxicol Pathol.

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011

    • Author(s)
      Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H
    • Journal Title

      Brain Res.

      Volume: 24 Pages: 97-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain2011

    • Author(s)
      Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K
    • Journal Title

      J.Neurosci.

      Volume: 31 Pages: 346-358

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Dopamine D2 receptor as a novel target molecule for heart-type fatty acid binding protein. Nihon Shinkei Seishin Yakurigaku Zasshi2011

    • Author(s)
      Shioda N, Yamamoto Y, Owada Y, Fukunaga K.
    • Volume
      31(3)
    • Pages
      125-30
    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21800703

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] The establishment of "evidence based medicine" for the treatment of cerebral stroke-bridgingbasic and clinical sciences-2011

    • Author(s)
      Tokuyama S, Fukunaga K
    • Journal Title

      YakugakuZasshi

      Volume: 131 Pages: 503-504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding2011

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K
    • Journal Title

      Eur.J.Pharmacol.

      Volume: 650 Pages: 621-628

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] CaMKIIδB Mediates Aberrant NCX1 Expression and the Imbalance of NCX1/SERCA in Transverse Aortic Constriction-Induced Failing Heart2011

    • Author(s)
      Lu YM, Huang J, Shioda N, Fukunaga K, Shirasaki Y, Li XM, Han F
    • Journal Title

      PLoS One.

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Dopamine D2 receptor as a novel target molecule for heart-type fatty acid binding protein2011

    • Author(s)
      Shioda N, Yamamoto Y, Owada Y, Fukunaga K
    • Journal Title

      Nihon Shinkei Seishin Yakurigaku Zasshi

      Volume: 31 Pages: 125-130

    • NAID

      10029094334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Abnormal dendritic spine morphology and its signal transduction mechanisms in mental retardation2011

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Seikagaku

      Volume: 83 Pages: 1113-1117

    • NAID

      10030345941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells2011

    • Author(s)
      Han F, Chen YX, Lu YM, Huang JY, Zhang GS, Tao RR, Ji YL, Liao MH, Fukunaga K, Qin ZH
    • Journal Title

      J.Pineal.Res.

      Volume: 51 Pages: 124-135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Melatonin ameliorates ischemic-like injury-evoked nitrosative stress : Involvement of HtrA2/PED pathways in endothelial cells2011

    • Author(s)
      Han F, Tao RR, Zhang GS, Lu YM, Liu LL, Chen YX, Lou YJ, Fukunaga K, Hong ZH
    • Journal Title

      J.Pineal.Res.

      Volume: 50 Pages: 281-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection2011

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Expert Opin.Ther.Targets.

      Volume: 15 Pages: 145-155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice2011

    • Author(s)
      Moriguchi S, Yamamoto Y, Ikuno T, Fukunaga K
    • Journal Title

      J Neurochem

      Volume: 117(5) Pages: 879-91

    • DOI

      10.1111/j.1471-4159.2011.07256.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109, KAKENHI-PROJECT-22659012
  • [Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior2011

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 131 Pages: 505-511

    • NAID

      130000678830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Establishment of"evidence based medicine" for the treatment of cerebral stroke-bridging basic and clinical sciences2011

    • Author(s)
      Tokuyama S, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi

      Volume: 131(4) Pages: 503-4

    • NAID

      130000678829

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21467788

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Drug development targeting for tyrosine phosphatase2011

    • Author(s)
      Fukunaga K
    • Journal Title

      Cell Tecnology

      Volume: 30 Pages: 631-636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] [Functional roles of constitutively active calcineurin in delayed neuron al death after brain ischemia].2011

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 13-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells.2011

    • Author(s)
      Han F, Chen YX, Lu YM, Huang JY, Zhang GS, Tao RR, JiYL, Llao MH, Fukunaga K, Qin ZH.
    • Journal Title

      J Pineal Res.

      Volume: 印刷中(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Melatonin ameliorates ischemic-like injury-evoked nitrosative stress : Involvement of NtrA2/PED pathways in endothelial cells.2011

    • Author(s)
      Han F, Tao RR, Zhang GS, LuYM, Liu LL, Chen YX, Lou YJ, Fukunaga K, Honk ZH.
    • Journal Title

      J Pineal Res.

      Volume: 50 Pages: 281-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation2011

    • Author(s)
      Oyagi A, Moriguchi S, Nitta A, Murata K, Oida Y, Tsuruma K, Shimazawa M, Fukunaga K, Hara H.
    • Journal Title

      Brain Res

      Volume: 1419 Pages: 97-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] Targeting sigma-1 receptor signaling by endogenous ligands for cardio protection.2011

    • Author(s)
      Bhuiyan MS, Fukunaga K.
    • Journal Title

      Expert Opin Ther Targets.

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Abnormal dendritic spine morphology and its signal transduction mechanisms in mental retardation2011

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Seikagaku

      Volume: 83 Pages: 1113-1117

    • NAID

      10030345941

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Melatonin ameliorates ischemic-like injury-evoked nitrosative stress : In volvement of HtrA2/PED pathways in endothelial cells.2011

    • Author(s)
      Han F, Tao RR, Zhang GS, Lu YM, Liu LL, Chen YX, Lou YJ, Fukunaga K, Hong ZH.
    • Journal Title

      J Pineal Res.

      Volume: 50 Pages: 281-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Melatonin ameliorates ischemic-like injury-evoked nitrosative stress : Involvement of HtrA2/PED pathways in endothelial cells2011

    • Author(s)
      Han F, Tao RR, Zhang GS, Lu YM, Liu LL, Chen YX, Lou YJ, Fukunaga K, Hong ZH
    • Journal Title

      J.Pineal.Res.

      Volume: 50 Pages: 281-291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Functional roles of constitutively active calcineurin in delayed neuronal death after brain ischemia2011

    • Author(s)
      Shioda N, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi

      Volume: 131(1) Pages: 13-20

    • NAID

      130000451520

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21212608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Ca(2+)/calinodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy2011

    • Author(s)
      Moriguchi S, Oomura Y, Shioda N, Han F, Hori N, Aou S, Fukunaga K
    • Journal Title

      Mol.Cell Neurosci.

      Volume: 46 Pages: 101-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior2011

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 131 Pages: 505-511

    • NAID

      130000678830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] The establishment of "evidence based medicine" for the treatment of cerebral stroke-bridaine basic and clinical sciences2011

    • Author(s)
      Tokuyama S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 503-504

    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Targeting nitrosative stress for neurovascular protection: new implications in brain diseases2011

    • Author(s)
      Tao RR, Ji YL, Lu YM, Fukunaga K, Han F
    • Journal Title

      Curr Drug Targets

      Volume: 13(2) Pages: 272-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Functional roles of constitutively active calcineurin in delayed neuronal death after brain ischemia2011

    • Author(s)
      Shioda N, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 131 Pages: 13-20

    • NAID

      130000451520

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Prandial increase of leptin in the brain activates spatial learning and memory2010

    • Author(s)
      Oomura Y, Aou S, Fukunaga K
    • Journal Title

      Pathophysiology

      Volume: 17 Pages: 119-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Quantitative measurement of In Vivo phosphorylation states of CdkS activator p35 by Phos-tag SDS-PAGE.2010

    • Author(s)
      Hosokawa T, Saito T, Asada A, Fukunaga K, Hisanaga SI
    • Journal Title

      Mol.Cell Proteomics.

      Volume: 9 Pages: 1133-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Inhibition of dystrophin breakdown and endothelial nitric-oxide synthase uncoupling accounts for cytoprotection by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate(DY-9760e)in left ventricular hypertrophied Mice.2010

    • Author(s)
      F.Han, YM.Lu, H.Hasegawa, H.Kanai, E.Hachimura, Y.Shirasaki, K.Fukunaga
    • Journal Title

      J.Pharmacol.Exp.Ther. 332

      Pages: 421-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypernophy and dysfunctions in mice.2010

    • Author(s)
      Tagashira H, Bhuiyan MS, Shioda N, Hasegawa H, Kana H, Fukunaga K
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Quantitative measurement of In Vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE.2010

    • Author(s)
      T.Hosokawa, T.Saito, A.Asada, K.Fukunaga, SI.Hisanaga
    • Journal Title

      Mol.Cell Proteomics. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Inhibition of dystrophin breakdown and endothelial nitric-oxide synthase uncoupling accounts for cytoprotection by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl] ethyl]-5, 6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3. 5 hydrate (DY-92010

    • Author(s)
      Han F, Lu YM, Hasegawa H, Kanai H, Hachimura E, Shirasaki Y, Fukunaga K.
    • Journal Title

      J Pharmacol Exp The

      Volume: 332(2) Pages: 421-8

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19889795

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions2010

    • Author(s)
      Bhuiyan MS, Tagashira H, Shioda N, Fukunaga K.
    • Journal Title

      Expert Opin Ther Targets

      Volume: 14(10) Pages: 1009-22

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20722474

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders : proteins interacting with the third cytoplasmic loop of dopamine D2 and D3 receptors2010

    • Author(s)
      Shioda N, Takeuchi Y, Fukunaga K.
    • Journal Title

      J Pharmacol Sci

      Volume: 114(1) Pages: 25-31

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20716856

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats.2010

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Exp Biol Med.

      Volume: 235 Pages: 356-364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Transcriptional upregulation of calcineurin Abeta by endothelin-1 is partially mediated by calcium/calmodulin-dependent protein kinase IIdelta3 in rat cardiomyocytes2010

    • Author(s)
      Lu YM, Shioda N, Yamamoto Y, Han F, Fukunaga K
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1799 Pages: 429-441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Characterization of an animal model of postmenopausal cardiac hypertrophy and novel mechanisms responsible for cardiac decompensation using ovariectomized pressure-overloaded rats.2010

    • Author(s)
      MS.Bhuiyan, K.Fukunaga
    • Journal Title

      Menopause 17

      Pages: 213-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice.2010

    • Author(s)
      K.Takao, K.Tanda, K.Nakamura, J.Kasahara, K.Nakao, M.Katsuki, K.Nakanishi, N.Yamasaki, K.Toyama, M.Adachi, M.Umeda, T.Araki, K.Fukunaga, H.Kondo, H.Sakagami, T.Miyakawa.
    • Journal Title

      PLoS One 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Expression profiling of Ca(2+)/calmodulin-dependent signaling molecules in the rat dorsal and ventral hippocampus after acute lead exposure2010

    • Author(s)
      Zhang GS, Ye WF, Tao RR, Lu YM, Shen GF, Fukunaga K, Huang JY, Ji YL, Han F.
    • Journal Title

      Exp Toxicol Pathol

    • DOI

      10.1016/j.etp.2010.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390108
  • [Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST10I, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice.2010

    • Author(s)
      Shioda N, Yamamoto Y, Ban F, Moriguchi S, Yamaguchi Y, Hino M, Fukunaga K
    • Journal Title

      J.Pharmacol.Exp.Ther.

      Volume: 333 Pages: 43-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-over load-induced hynertronhy and dysfunctions.2010

    • Author(s)
      Bhuiyan MS, Tagashira H, Shioda N, Fukunaga K
    • Journal Title

      Expert Opin Ther Targets.

      Volume: 14 Pages: 1009-1022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain2010

    • Author(s)
      N. Shioda, Y. Yamamoto, M. Watanabe, B. Binas, Y. Owada, K. Fukunaga
    • Journal Title

      J Neurosci. 30

      Pages: 3146-3155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice2010

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Yamaguchi Y, Hino M, Fukunaga K
    • Journal Title

      J. Pharmacol. Exp. Ther

      Volume: 333 Pages: 43-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Inhibition of dystrophin breakdown and endothelial nitric-oxide synthase uncoupling accounts for cytoprotection by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e) in left ventricular hypertrophied Mice2010

    • Author(s)
      F. Han, YM. Lu, H. Hasegawa, H. Kanai, E. Hachimura, Y. Shirasaki, K. Fukunaga
    • Journal Title

      J.Pharmacol.Exp.Ther. 332

      Pages: 421-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKbeta in neurite spine formation, contributing to cognitive function2010

    • Author(s)
      Shirai Y, Kouzuki T, Kakefuda K, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, Saito N, Hara H
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] ranscriptional upregulation of calcineurin Abeta by endothelin-1 is partially mediated by calcium/calmodulin-dependent protein kinase IIdelta3 in rat cardiomyocytes.2010

    • Author(s)
      YM.Lu, N.Shioda, Y.Yamamoto, F.Han, K.Fukunaga
    • Journal Title

      Biochim.Biophys.Acta. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Expression profiling of Ca(2+)/calmodulin-dependent signaling molecules in the rat dorsal and ventral hippocampus after acute lead exposure2010

    • Author(s)
      Zhang GS, Ye WF, Tao RR, Lu YM, Shen GF, Fukunaga K, Huang JY, Ji YL, Han F.
    • Journal Title

      Exp Toxicol Pathol

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/21195594

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-over bad-induced hypertrophy and dysfUnctions.2010

    • Author(s)
      Bhuiyan MS, Tagashira H, Shioda N, Fukunaga K
    • Journal Title

      Expert Opin Ther Targets.

      Volume: 14 Pages: 1009-1022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain.2010

    • Author(s)
      N.Shioda, Y.Yamamoto, M.Watanabe, B.Binas, Y.Owada, K.Fukunaga
    • Journal Title

      J.Neurosci. 30

      Pages: 3146-3155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain2010

    • Author(s)
      Shioda N, Yamamoto Y, Watanabe M, Binas B, Owada Y, Fukunaga K
    • Journal Title

      J Neurosci

      Volume: 30 Pages: 3146-3155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Inhibition of dystrophin breakdown and endothelial nitric-oxide synthase uncouplingaccounts for cytoprotection by3-[2-[4-(3-chloro-2-methylphenyl)-1-piperaz inyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylm ethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e) in left ventricular hypertrophied Mice2010

    • Author(s)
      Han F, Lu YM, Hasegawa H, Kanai H, Hachimura E, Shirasaki Y, Fukunaga K
    • Journal Title

      J. Pharmacol. Exp. Ther

      Volume: 332 Pages: 421-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats2010

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Exp BiolMed

      Volume: 235 Pages: 356-364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Characterization of an animal model of postmenopausal cardiac hypertrophy and novel mechanisms responsible for cardiac decompensation using ovariectomized pressure-overloaded rats2010

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Menopause

      Volume: 17 Pages: 213-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olf actory Bulbectomized Mice.2010

    • Author(s)
      N.Shioda, Y.Yamamoto, F.Han, S.Moriguchi, Y.Yamaguchi, M.Hino, K.Fukunaga
    • Journal Title

      J.Pharmacol.Exp.Ther. 333

      Pages: 43-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice.2010

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Yamaguchi Y, Hino M, Fukunaga K
    • Journal Title

      J.Pharmacol.Exp.Ther.

      Volume: 333 Pages: 43-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Donepezil-induced neuroprotection of acetykholinergic neurons in olfactory bulbectomized mice2010

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 130 Pages: 717-721

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions2010

    • Author(s)
      Bhuiyan MS, Tagashira H, Shioda N, Fukunaga K
    • Journal Title

      Expert Opin Ther Targets

      Volume: 14 Pages: 1009-1022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Characterization of an animal model of postmenopausal cardiac hypert rophy and novel mechanisms responsible for cardiac decompensation using ovariectomized pressure-overloaded rats.2010

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Menopause

      Volume: 17 Pages: 213-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice.2010

    • Author(s)
      K.Takao, K.Tanda, K.Nakamura, J.Kasahara, K.Nakao, M.Katsuki, K.Nakanishi, N.Yamasaki, K.Toyama, M.Adachi, M.Umeda, T.Araki, K.Fukunaga, H.Kondo, H.Sakagami, T.Miyakawa
    • Journal Title

      PLoS One 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Quantitative measurement of In Vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE.2010

    • Author(s)
      T.Hosokawa, T.Saito, A.Asada, K.Fukunaga, SI.Hisanaga
    • Journal Title

      Mol.Cell Proteomics. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Sigma1-receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice2010

    • Author(s)
      Tagashira H, Bhuiyan S, Shioda N, Hasegawa H, Kanai H, Fukunaga K.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 299(5)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20802134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Quantitative measurement of In Vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE.2010

    • Author(s)
      Hosokawa T, Saito T, Asada A Fukunaga K, Hisanaga SI
    • Journal Title

      Mol.Cell Proteomics

      Volume: 9 Pages: 1133-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain2010

    • Author(s)
      Shioda N, Yamamoto Y, Watanabe M, Binas B, Owada Y, Fukunaga K.
    • Journal Title

      J Neurosci

      Volume: 30(8) Pages: 3146-55

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20181611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells.2010

    • Author(s)
      Kajihara R, Fukushige S, Shioda N, Tanabe K, Fukunaga K, Inui S
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 401 Pages: 350-355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain.2010

    • Author(s)
      N.Shioda, Y.Yamamoto, M.Watanabe, B.Binas, Y.Owada, K.Fukunaga
    • Journal Title

      J.Neurosci. 30

      Pages: 3146-3155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Expression profiling of Ca(2+)/calmodulin-dependent signaling molecules in the rat dorsal and ventral hippocampus after acute lead exposure2010

    • Author(s)
      Zhang GS, Ye WF, Tao RR, Lu YM, Shen GF, Fukunaga K, Huang JY, Ji YL, Han F
    • Journal Title

      Exp Toxicol Pathol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Transcriptional upregulation of calcineurin Abeta by endothelin-1 is partially mediated by calcium/calmodulin-dependent protein kinase IIdelta3 in rat cardiomyocytes2010

    • Author(s)
      Lu YM, Shioda N, Yamamoto Y, Han F, Fukunaga K.
    • Journal Title

      Biochim Biophys Acta

      Volume: 1799(5-6) Pages: 429-41

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/2021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKbeta in neurite spine formation, contributing to cognitive function2010

    • Author(s)
      Shirai Y, Kouzuki T, Kakefuda K, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, Saito N, Hara H.
    • Journal Title

      PLoS One

      Volume: 5(7)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20657643

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Dehydroepiandrosterone-Mediated Stimulation of Sigma-1 Receptor Activates Akt-eNOS Signaling in the Thoracic Aorta of Ovariectomized Rats with Abdominal Aortic Banding.2010

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K
    • Journal Title

      Cardiovasc Ther.

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hypertension-induced kidney hypertrophy in ovariectomized rats.2010

    • Author(s)
      Bhuiyan S, Fukunaga K.
    • Journal Title

      Exp Biol Med (Maywood)

      Volume: 235(3) Pages: 356-64

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20404054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Characterization of an animal model of postmenopausal cardiac hypertrophy and novel mechanisms responsible for cardiac decompensation using ovariectomized pressure-overloaded rats.2010

    • Author(s)
      MS.Bhuiyan, K.Fukunaga
    • Journal Title

      Menopause 17

      Pages: 213-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice.2010

    • Author(s)
      N.Shioda, Y.Yamamoto, F.Han, S.Moriguchi, Y.Yamaguchi, M.Hino, K.Fukunaga
    • Journal Title

      J.Pharmacol.Exp.Ther. 333

      Pages: 43-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Vezatin, a potential target for ADP-ribosylation factor 6, regulates the dendritic formation of hippocampal neurons.2010

    • Author(s)
      M.Sanda, N.Ohara, A.Kamata, Y.Hara, H.Tamaki, J.Sukegawa, T.Yanagisawa, K.Fukunaga, H.Kondo, H.Sakagami
    • Journal Title

      Neurosci.Res. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells2010

    • Author(s)
      Kajihara R, Fukushige S, Shioda N, Tanabe K, Fukunaga K, Inui S.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 401(3) Pages: 350-5

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20851109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Transcriptional upregulation of calcineurin Abeta by endothelin-1 is partially mediated by calcium/calmodulin-dependent protein kinase IIdeltai in rat cardiomyocytes.2010

    • Author(s)
      Lu YM, Shioda N, Yamamoto Y, Han F, Fukunaga K
    • Journal Title

      Biochim.Biophys.Acta.

      Volume: 1799 Pages: 429-441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] [Donepezil-induced neuroprotection of acetylcholinergic neurons in olfactory bulbectomized mice]2010

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi.

      Volume: 130 Pages: 717-721

    • NAID

      130000259461

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders : Proteins Interacting With the Third Cytoplasmic Loop of Dopamine D(2)and D(3)Receptors.2010

    • Author(s)
      Shioda N, Takeuchi Y, Fukunaga K
    • Journal Title

      J Phannacol Sci.

      Volume: 114 Pages: 25-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunctions in mice2010

    • Author(s)
      Tagashira H, Bhuiyan MS, Shioda N, Hasegawa H, Kanai H, Fukunaga K
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Transcriptional upregulation of calcineurin Abeta by endothelin-1 is partially mediated by calcium/calmodulin-dependent protein kinase IIdelta3 in rat cardiomyocytes.2010

    • Author(s)
      Lu YM, Shioda N, Yamamoto Y, Han F, Fukunaga K
    • Journal Title

      Biochim.Biophys.Acta.

      Volume: 1799 Pages: 429-441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain.2010

    • Author(s)
      Shioda N, Yamamoto Y, Watanabe M, Binas B, Owada Y, Fukunaga K
    • Journal Title

      J Neurosci.

      Volume: 30 Pages: 3146-3155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Vezatin, a potential target for ADP-ribosylation factor 6, regulates the dendritic formation of hippocam pal neurons.2010

    • Author(s)
      Sanda M, Ohara N, Kamata A, Hara Y, Tamaki H, Sukegawa J, Yanagisawa T, Fukunaga K, Kondo H, Sakagami H
    • Journal Title

      Neurosci.Res.

      Volume: 67 Pages: 126-136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Donepezil-induced neuroprotection of acetylcholinergic neurons in olfactory bulbectomized mice2010

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi

      Volume: 130(5) Pages: 717-21

    • NAID

      130000259461

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20460870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Donepezil-induced neuroprotection of acetylcholinergic neurons in olfactory bulbectomized mice2010

    • Author(s)
      Yamamoto Y, Shioda N, Han F, Moriguchi S, Fukunaga K
    • Journal Title

      Yakugaku Zasshi

      Volume: 130 Pages: 717-721

    • NAID

      130000259461

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Platelet-activating factor-induced synaptic facilitation is associated with increased calcium/calrnodulin-dependent protein kinase II, protein kinase C and extracellular signal-regulated kinase activities in the rat hippocampal CAl region.2010

    • Author(s)
      Moriguchi S, Shioda N, Yamamoto Y, Fukunaga K
    • Journal Title

      Neuroscience.

      Volume: 166 Pages: 1158-1166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Dehydroepiandrosterone-Mediated Stimulation of Sigma-1 Receptor Activates Akt-eNOS Signaling in the Thoracic Aorta of Ovariectomized Rats with Abdominal Aortic Banding2010

    • Author(s)
      Bhuiyan MS, Tagashira H, Fukunaga K
    • Journal Title

      Cardiovasc Ther

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice.2010

    • Author(s)
      Takao K, Tanda K, Nakamura K, Kasahara J, Nakao K, Katsuki M, Nakanishi K, Yamasaki N, Toyama K, Adachi M, Umeda M, Araki T, Fukunaga K, Kondo H, Sakagami H, MiyakawaT
    • Journal Title

      PLoS One.

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Essential role of neuron-enriched diacylglycerol kinase(DGK), DGKbeta in neurite spine formation, contributing to cognitive function.2010

    • Author(s)
      Shirai Y, Kouzuki T, KakefudaK, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, SaitoN, Hara H
    • Journal Title

      PLoS One.

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKb eta in neurite spine formation, contributing to cognitive function.2010

    • Author(s)
      Shirai Y, Kouzuki T, Kakefuda K, Moriguchi S, Oyagi A, Horie K, Morita SY, Shimazawa M, Fukunaga K, Takeda J, Saito N, Hara H
    • Journal Title

      PLoS One.

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells.2010

    • Author(s)
      QB.Liu, LL.Liu, YM.Lu, RR.Tao, JY.Huang, N.Shioda, S.Moriguchi, K.Fukunaga.F.Han, YJ.Lou
    • Journal Title

      Toxicol.Appl.Pharmacol. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Reduced expression of the ATRX gene, a chromatin-remodeling factor causes hippocampal dysfunction in mice.2010

    • Author(s)
      Nogami T, Beppu H, Tokoro T, Moriguchi S, Shioda N, Fukunaga K, Ohtsuka T, Ishii Y, Sasahara M, Shimada Y, Nishijo H, Li E, Kitajima I
    • Journal Title

      Hippocampus.

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice2010

    • Author(s)
      Takao K, Tanda K, Nakamura K, Kasahara J, Nakao K, Katsuki M, Nakanishi K, Yamasaki N, Toyama K, Adachi M, Umeda M, Araki T, Fukunaga K, Kondo H, Sakagami H, Miyakawa T.
    • Journal Title

      PLoS One

      Volume: 5(3)

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20209163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Heart-type fatty acid binding protein regulates dopamine D2 receptor function in mouse brain.2010

    • Author(s)
      Shioda N, Yamamoto Y, Watanabe M, Binas B, Owada Y, Fukunaga K
    • Journal Title

      J Neurosci.

      Volume: 30 Pages: 3146-3155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Characterization of an animal+mode of postmenopausal cardiac hypert rophy and novel.mechanisms responsible for cardiac decompensation using ovariectomized pressure-overloaded rats.2010

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Menopause

      Volume: 17 Pages: 213-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] A novel cognitive enhancer, ZSET1446/ST101, promotes hippocampal neurogenesis and ameliorates depressive behavior in olfactory bulbectomized mice2010

    • Author(s)
      Shioda N, Yamamoto Y, Han F, Moriguchi S, Yamaguchi Y, Hino M, Fukunaga K.
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 333(1) Pages: 43-50

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/2006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Quantitative measurement of in vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE2010

    • Author(s)
      Hosokawa T, Saito T, Asada A, Fukunaga K, Hisanaga S.
    • Journal Title

      Mol Cell Proteomics

      Volume: 9(6) Pages: 1133-43

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20097924

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells2010

    • Author(s)
      Kajihara R, Fukushige S, Shioda N, Tanabe K, Fukunaga K, Inui S
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 401 Pages: 350-355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Vezatin, a potential target for ADP-ribosylation factor 6, regulates the dendritic formation of hippocampal neurons.2010

    • Author(s)
      M.Sanda, N.Ohara, A.Kamata, Y.Hara, H.Tamaki, J.Sukegawa, T.Yanagisawa, K.Fukunaga, H.Kondo, H.Sakagami
    • Journal Title

      Neurosci.Res. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Vezatin, a potential target for ADP-ribosylation factor 6, regulates the dendritic formation of hippocampal neurons2010

    • Author(s)
      Sanda M, Ohara N, Kamata A, Hara Y, Tamaki H, Sukegawa J, Yanagisawa T, Fukunaga K, Kondo H, Sakagami H.
    • Journal Title

      Neurosci Res

      Volume: 67(2) Pages: 126-36

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/20188128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Inhibition of dystrophin breakdown and endothelial nitric-oxide synthase uncoupling accounts for cytoprotection by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e) in left ventricular hypertrophied Mice.2010

    • Author(s)
      F.Han, YM.Lu, H.Hasegawa, H.Kanai, E.Hachimura, Y.Shirasaki, K.Fukunaga
    • Journal Title

      J.Pharmacol.Exp.Ther. 332

      Pages: 421-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Quantitative measurement of In Vivo phosphorylation states of Cdk5 activator p35 by Phos-tag SDS-PAGE2010

    • Author(s)
      Hosokawa T, Saito T, Asada A, Fukunaga K, Hisanaga SI
    • Journal Title

      Mol. Cell Proteomics

      Volume: 9 Pages: 1133-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Stimulation of Sigma-1 receptor by dehydroepiandrosterone ameliorates hynertension-induced kidney hynertronhy in ovariectomized rats.2010

    • Author(s)
      Bhuiyan MS, Fukunaga K
    • Journal Title

      Exp Biol Med.

      Volume: 235 Pages: 356-364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Vezatin, a potential target for ADP-ribosylation factor 6, regulates the dendritic formation of hippocampal neurons2010

    • Author(s)
      Sanda M, Ohara N, Kamata A, Hara Y, Tamaki H, Sukegawa J, Yanagisawa T, Fukunaga K, Kondo H, Sakagami H
    • Journal Title

      Neurosci. Res

      Volume: 67 Pages: 126-136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Vezatin, a potential target for ADP-ribosylation factor 6, regulates the dendritic formation of hippocampal neurons.2010

    • Author(s)
      Sanda M, Ohara N, Kamata A, Hara Y, Tamaki H, Sukegawa J, Yanagisawa T, Fukunaga K, Kondo H, Sakagami H
    • Journal Title

      Neurosci.Res.

      Volume: 67 Pages: 126-136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice.2010

    • Author(s)
      Takao K, Tanda K, Nakamura K, Kasahara J, Nakao K, Katsuki M, Nakanishi K, Yamasaki N, Toyama K, Adachi M, Umeda M, Araki T, Fukunaga K, Kondo H, Sakagami H, Miyakawa T
    • Journal Title

      PLoS One.

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice2010

    • Author(s)
      Takao K, Tanda K, Nakamura K, Kasahara J, Nakao K, Katsuki M, Nakanishi K, Yamasaki N, Toyama K, Adachi M, Umeda M, Araki T, Fukunaga K, Kondo H, Sakagami H, Miyakawa T
    • Journal Title

      PLoS One

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] CaMKII phosphorylates serine 10 of p27 and confers apoptosis resista nee to HeLa cells.2010

    • Author(s)
      Kajihara R, Fukushige S, Shioda N, Tanabe K, Fukunaga K, Inui S
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 401 Pages: 350-355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Platelet-activating factor-induced synaptic facilitation is associated with increased calcium/calmodulin-dependent protein kinase II, protein kinase C and extracellular signal-regulated kinase activities in the rat hip pocampal CA1 region.2010

    • Author(s)
      Moriguchi S, Shioda N, Yamamoto Y, Fukunaga K
    • Journal Title

      Neuroscience.

      Volume: 166 Pages: 1158-1166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] A Novel Cognitive Enhancer, ZSET1446/ST101, Promotes Hippocampal Neurogenesis and Ameliorates Depressive Behavior in Olfactory Bulbectomized Mice2010

    • Author(s)
      N. Shioda, Y. Yamamoto, F. Han, S. Moriguchi, Y. Yamaguchi, M. Hino, K. Fukunaga
    • Journal Title

      J.Pharmacol.Exp.Ther. 333

      Pages: 43-50

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Characterization of an animal model of postmenopausal cardiac hypertrophy and novel mechanisms responsible for cardiac decompensation using ovariectomized pressure-overloaded rats2010

    • Author(s)
      Bhuiyan MS, Fukunaga K.
    • Journal Title

      Menopause

      Volume: 17(1) Pages: 213-21

    • URL

      http://www.ncbi.nlm.nih.gov/pubmed/19741553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Transcriptional upregulation of calcineurin Abeta by endothelin-1 is partially mediated by calcium/calmodulin-dependent protein kinase IIdelta3 in rat cardiomyocytes2010

    • Author(s)
      YM. Lu, N. Shioda, Y. Yamamoto, F. Han, K. Fukunaga
    • Journal Title

      Biochim.Biophys.Acta. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders : Proteins Interacting With the Third C ytoplasmic Loop of Dopamine D(2) and D(3) Receptors.2010

    • Author(s)
      Shioda N, Takeuchi Y, Fukunaga K
    • Journal Title

      J Pharmacol Sci.

      Volume: 114 Pages: 25-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders:Proteins Interacting With the Third Cytoplasmic Loop of Dopamine D(2) and D(3) Receptors2010

    • Author(s)
      Shioda N, Takeuchi Y, Fukunaga K
    • Journal Title

      J Pharmacol Sci

      Volume: 114 Pages: 25-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] ranscriptional upregulation of calcineurin Abeta by endothelin-1 is partially mediated by calcium/calmodulin-dependent protein kinase IIdelta3 in rat cardiomyocytes.2010

    • Author(s)
      YM.Lu, N.Shioda, Y.Yamamoto, F.Han, K.Fukunaga
    • Journal Title

      Biochim.Biophys.Acta. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Inhibition of dystrophin breakdown and endothelial nitric-oxide synthase uncoupling accounts for cytoprotection by 3-[2-[4-(3-chloro-2-meth ylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-l-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e) in left ventricular by nertroohied Mice.2010

    • Author(s)
      Han F, Lu YM, Hasegawa H, Kanai H, Hachimura E, Shirasaki Y, Fukunaga K
    • Journal Title

      J.Pharmacol.Exp.Ther.

      Volume: 332 Pages: 421-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Inhibition of dystrophin breakdown and endothelial nitric-oxide synihase uncoupling accounts for cytoprotection by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethy1]-5,6-dimethoxy-1-(4-imidazolylmethyl)-iH-indazole dihydrochloride 3.5 hydrate(DY-9760e)in left ventricular bypertrophied Mice.2010

    • Author(s)
      Han F, Lu YM, Hasegawa H, Kanai H, Hachimura E, Shirasaki Y, Fukunaga K
    • Journal Title

      J.Pharmacol.Exp.Ther

      Volume: 332 Pages: 421-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659012
  • [Journal Article] Sigma-1 receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunctions in mice.2010

    • Author(s)
      Tagashira H, Bhuiyan MS, Shioda N, Hasegawa H, Kanai H, Fukunaga K
    • Journal Title

      Am J Physiol Heart Circ Physiol.

      Volume: 299 Pages: 1535-1545

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390109
  • [Journal Article] Chronic beta-AR activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized female rats.2009

    • Author(s)
      MS.Bhuiyan, N.Shioda, K.Fukunaga
    • Journal Title

      Expert Opin.Ther.Targets 13

      Pages: 275-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] DY-9760e Inhibits Endothelin-1-induced Cardiomyocyte Hypertrophy Through Inhibition of CaMKII and ERK Activities2009

    • Author(s)
      Lu YM, Shioda N, Han F, Kamata A, Shirasaki Y, Qin ZH. Fukunaga K.
    • Journal Title

      Cardiovasc Ther 27

      Pages: 17-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice.2009

    • Author(s)
      S.Moriguchi, F.Han, N.Shioda, Y.Yamamoto, T.Nakajima, O.Nakagawasai, T.Tadano, JZ.Yeh, T.Narahashi, K.Fukunaga
    • Journal Title

      J.Neurochem. 110

      Pages: 170-181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats.2009

    • Author(s)
      MS.Bhuiyan, N.Shioda, M.Shibuya, Y.Iwabuchi, K.Fukunaga
    • Journal Title

      Hypertension 53

      Pages: 57-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Prandial increase of leptin in the brain activates spatial learning and memory.2009

    • Author(s)
      Y.Oomura, S.Aou, K.Fukunaga
    • Journal Title

      Pathophysiology 17

      Pages: 119-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Down-regulation of Bcl-2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum.2009

    • Author(s)
      XD.Zhang, Y.Wang, JC.Wu, X.F.Lin, R.Han, F.Han, K.Fukunaga, ZH.Qin.
    • Journal Title

      J.Neurosci.Res. 87

      Pages: 3600-3610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Chronic beta-AR activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized female rats.2009

    • Author(s)
      MS.Bhuiyan, N.Shioda, K.Fukunaga
    • Journal Title

      Expert Opin.Ther.Targets 13

      Pages: 275-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Role of heart-type fatty acid binding protein in the brain function2009

    • Author(s)
      Motohashi K, Yamamoto Y, Shioda N, Kondo H, Owada Y, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi. 129

      Pages: 191-195

    • NAID

      110007046096

    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] The postsynaptic density protein, IQ-ArfGEF/BRAG1, can interact with IRSp53, through its proline-rich sequence.2009

    • Author(s)
      M.Sanda, A.Kamata, O.Katsumata, K.Fukunaga, M.Watanabe, H.Kondo, H.Sakagami
    • Journal Title

      Brain Res. 1251

      Pages: 7-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum.2009

    • Author(s)
      XD.Zhang, Y.Wang, Y.Wang, X.Zhang, R.Han, JC.Wu, ZQ.Liang, ZL.Gu, F.Han, K.Fukunaga, ZH.Qin
    • Journal Title

      Autophagy 5

      Pages: 339-350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] The postsynaptic density protein, IQ-ArfGEF/BRAG1, can interact with IRSp53 through its proline-rich sequence2009

    • Author(s)
      Sanda M, Kamata A, Katsumata O, Fukunaga K, Watanabe M, Kondo H, Sakagami H.
    • Journal Title

      Brain Res 1251

      Pages: 7-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Chronic beta-AR activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized female rats2009

    • Author(s)
      Bhuiyan MS, Shioda N, Fukunaga K.
    • Journal Title

      Expert Opin Ther Targets. 13

      Pages: 275-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Stimulation of Sigma-1 receptor signaling by dehydroepiandrosterone ameliorates pressure overload-induced hypertrophy and dysfunctions in ovariectomized rats.2009

    • Author(s)
      MS.Bhuiyan, K.Fukunaga
    • Journal Title

      Expert Opin.Ther.Targets 13

      Pages: 1253-1265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Improvement of depressive behaviors by nefiracetam is associated with activation of CaM kinases in olfactory bulbectomized mice.2009

    • Author(s)
      F.Han, T.Nakano, Y.Yamamoto, N.Shioda, YM.Lu, K.Fukunaga
    • Journal Title

      Brain Res. 1265

      Pages: 205-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats2009

    • Author(s)
      Bhuiyan MS, Shioda N, Shibuya M, Iwabuchi Y, Fukunaga K.
    • Journal Title

      Hypertension 53

      Pages: 57-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation.2009

    • Author(s)
      S.Moriguchi, N.Shioda, F.Han, JZ.Yeh, T.Narahashi, K.Fukunaga
    • Journal Title

      Hippocampus 19

      Pages: 844-854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] p53 mediates mitochondria dysfunction-triggered autophagy activation and cell death in rat striatum.2009

    • Author(s)
      XD.Zhang, Y.Wang, Y.Wang, X.Zhang, R.Han, JC.Wu, ZQ.Liang, ZL.Gu, F.Han, K.Fukunaga, ZH.Qin
    • Journal Title

      Autophagy 5

      Pages: 339-350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats2009

    • Author(s)
      Bhuiyan MS, Shioda N, Shibuya M, Iwabuchi Y, Fukunaga K.
    • Journal Title

      Hypertension. 53

      Pages: 57-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Mitochondrial serine protease HtrA2/Omi as a potential therapeutic target.2009

    • Author(s)
      MS.Bhuiyan, K.Fukunaga
    • Journal Title

      Curr.Drug Targets 10

      Pages: 372-383

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] The postsynaptic density protein, IQ-ArfGEF / BRAG1, can interact with IRSp53 through its proline-rich sequence2009

    • Author(s)
      Sanda M, Kamata A, Katsumata O, Fukunaga K, Watanabe M, Kondo. H. Sakagami H.
    • Journal Title

      Brain Res. 1251

      Pages: 7-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Nefiracetam and Galantamine Modulation of Excitatory and Inhibitory Synaptic Transmission via Stimulation of Neuronal Nicotinic Acetylcholine Receptors in Rat Cortical Neurons2009

    • Author(s)
      Moriguchi S, Zhao X, Marszalec W, Yeh JZ, Fukunaga K, Narahashi T.
    • Journal Title

      Neuroscience (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Role of Akt and ERK signaling in the neurogenesis following brain ischemia.2009

    • Author(s)
      N.Shioda, F.Han, K.Fukunaga
    • Journal Title

      Int.Rev.Neurobiol. 85

      Pages: 375-387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Prandial increases of leptin and orexin in the brain modulate spatial learning and memory.2009

    • Author(s)
      Y.Oomura, S.Aou, K.Fukunaga, S.Moriguchi, K.Sasaki
    • Journal Title

      Ross.Fiziol.Zh.Im.I.M.Sechenova 95

      Pages: 1373-1385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Role of Akt and ERK signaling in the neurogenesis following brain ischemia.2009

    • Author(s)
      N.Shioda, F.Han, K.Fukunaga
    • Journal Title

      Int.Rev.Neurobiol. 85

      Pages: 375-387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats2009

    • Author(s)
      MS. Bhuiyan, N. Shioda, M. Shibuya, Y. Iwabuchi, K. Fukunaga
    • Journal Title

      Hypertension 53

      Pages: 57-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Activation of endothelial nitric oxide synthase by a vanadium compound ameliorates pressure overload-induced cardiac injury in ovariectomized rats.2009

    • Author(s)
      MS.Bhuiyan, N.Shioda, M.Shibuya, Y.Iwabuchi, K.Fukunaga
    • Journal Title

      Hypertension 53

      Pages: 57-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Improvement of depressive behaviors by nefiracetam is associated with activation of CaM kinases in olfactory bulbectomized mice2009

    • Author(s)
      Han F, Nakano T, Yamamoto Y, Shioda N, Lu YM, Fukunaga K
    • Journal Title

      Brain Res. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Nefiracetam and galantamine modulation of excitatory and inhibitory synaptic transmission via stimulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons.2009

    • Author(s)
      S.Moriguchi, X.Zhao, W.Marszalec, JZ.Yeh, K.Fukunaga, T.Narahashi
    • Journal Title

      Neuroscience 160

      Pages: 484-491

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Down-regulation of Bcl-2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum.2009

    • Author(s)
      XD.Zhang, Y.Wang, JC.Wu, X.F.Lin, R.Han, F.Han, K.Fukunaga, ZH.Qin.
    • Journal Title

      J.Neurosci.Res. 87

      Pages: 3600-3610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Improvement of depressive behaviors by nefiracetam is associated with activation of CaM kinases in olfactory bulbectomized mice2009

    • Author(s)
      F.Han, T.Nakano, Y.Yamamoto, N.Shioda, YM.Lu, K.Fukunaga
    • Journal Title

      Brain Res. 1265

      Pages: 205-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation2009

    • Author(s)
      Moriguchi S, Shioda N, Han F, Yeh JZ, Narahashi T, Fukunaga K.
    • Journal Title

      Hippocampus (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice.2009

    • Author(s)
      S.Moriguchi, F.Han, N.Shioda, Y.Yamamoto, T.Nakajima, O.Nakagawasai, T.Tadano, JZ.Yeh, T.Narahashi, K.Fukunaga
    • Journal Title

      J.Neurochem. 110

      Pages: 170-181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation.2009

    • Author(s)
      Y.Yamamoto, N.Shioda, F.Han, S.Moriguchi, A.Yokosuka, Y.Mimaki, Y.Sashida, T.Yamakuni, Y.Ohizumi, K.Fukunaga
    • Journal Title

      Brain Res. 1295

      Pages: 218-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Improvement of depressive behaviors by nefiracetam is associated with activation of CaM kinases in olfactory bulbectomized mice2009

    • Author(s)
      Han F, Nakano T, Yamamoto Y, Shioda N, Lu YM, Fukunaga K.
    • Journal Title

      Brain Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] lomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine.2009

    • Author(s)
      XF.Fei, ZH.Qin, B.Xiang, LY.Li, F.Han, K.Fukunaga, ZQ.Liang
    • Journal Title

      Brain Res. 1264

      Pages: 85-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities.2009

    • Author(s)
      YM.Lu, N.Shioda, F.Han, A.Kamata, Y.Shirasaki, ZH.Qin, K.Fukunaga
    • Journal Title

      Cardiovasc.Ther. 27

      Pages: 17-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Role of heart-type fatty acid binding protein in the brain function2009

    • Author(s)
      Motohashi K, Yamamoto Y, Shioda N, Kondo H, Owada Y, Fukunaga K.
    • Journal Title

      Yakugaku Zasshi 129

      Pages: 191-195

    • NAID

      110007046096

    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Generation and Characterization of Conditional Heparin-Binding EGF-Like Growth Factor Knockout Mice.2009

    • Author(s)
      A.Oyagi, Y.Oida, K.Kakefuda, M.Shimazawa, N.Shioda, S.Moriguchi, K.Kitaichi, D.Nanba, K Yamaguchi, Y.Furuta, K.Fukunaga, S.Higashiyama, H.Hara.
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazole(DY-9836), a novel calmodulin antagonist.2009

    • Author(s)
      M.Lu, F.Han, N.Shioda, S.Moriguchi. Y.Shirasaki, ZH.Qin, K.Fukunaga
    • Journal Title

      Mol.Pharmacol. 75

      Pages: 101-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] The postsynaptic density protein, IQ-ArfGEF/BRAG1, can interact with IRSp53 through its proline-rich sequence.2009

    • Author(s)
      M.Sanda, A.Kamata, O.Katsumata, K.Fukunaga, M.Watanabe, H.Kondo, H.Sakagami
    • Journal Title

      Brain Res. 1251

      Pages: 7-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities2009

    • Author(s)
      YM. Lu, N. Shioda, F. Han, A. Kamata, Y. Shirasaki, ZH. Qin, K. Fukunaga
    • Journal Title

      Cardiovasc.Ther. 27

      Pages: 17-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Galantamine enhancement of long-term potentiation is mediated by calcium / calmodulin-dependent protein kinase II and protein kinase C activation2009

    • Author(s)
      Moriguchi S, Shioda N, Han F, Yeh JZ, Narahashi T, Fukunaga K.
    • Journal Title

      Hippocampus. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazol e (DY-9836), a novel calmodulin antagonist2009

    • Author(s)
      YM. Lu, F. Han, N. Shioda, S. Moriguchi. Y. Shirasaki, ZH. Qin, K. Fukunaga
    • Journal Title

      Mol.Pharmacol. 75

      Pages: 101-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation.2009

    • Author(s)
      Y.Yamamoto, N.Shioda, F.Han, S.Moriguchi, A.Yokosuka, Y.Mimaki, Y.Sashida, T.Yamakuni, Y.Ohizumi, K.Fukunaga
    • Journal Title

      Brain Res. 1295

      Pages: 218-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Chronic beta-AR activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized female rats2009

    • Author(s)
      Bhuiyan MS, Shioda N, Fukunaga K.
    • Journal Title

      Expert Opin Ther Targets 13

      Pages: 275-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] DY-9760e inhibits endothelin-1-induced cardiomyocyte hypertrophy through inhibition of CaMKII and ERK activities.2009

    • Author(s)
      YM.Lu, N.Shioda, F.Han, A.Kamata, Y.Shirasaki, ZH.Qin, K.Fukunaga
    • Journal Title

      Cardiovasc.Ther. 27

      Pages: 17-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] The Function of CaM Kinase II in Synaptic Plasticity and Spine Formation.2009

    • Author(s)
      K.Fukunaga, N.Shioda, E.Miyamoto
    • Journal Title

      Handobook of Neurochemistry and Molecular Neurobiology. Neural Signaling Mechanisms(ed.A.Lajtha.Vol.ed.K.)(Mikoshiba, Springer)

      Pages: 163-184

    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Generation and Characterization of Conditional Heparin-Binding EGF-Like Growth Factor Knockout Mice.2009

    • Author(s)
      A.Oyagi, Y.Oida, K.Kakefuda, M.Shimazawa, N.Shioda, S.Moriguchi, K.Kitaichi, D.Nanba, K.Yamaguchi, Y.Furuta, K.Fukunaga, S.Higashiyama, H.Hara
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyllethyl]-5, 6-dimethoxyindazole (DY-9836), a novel calmodulin antagonist2009

    • Author(s)
      Lu Ym, Han F, Shioda N, Moriguchi S, Shirasaki Y, Qin ZH, Fukunaga K.
    • Journal Title

      Mol Pharmacol. 75

      Pages: 101-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Stimulation of Sigma-1 receptor signaling by dehydroepiandroster one ameliorates pressure overload-induced hypertrophy and dysfunctions in ovariectomized rats.2009

    • Author(s)
      MS.Bhuiyan, K.Fukunaga
    • Journal Title

      Expert Opin.Ther.Targets 13

      Pages: 1253-1265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Prandial increases of leptin and orexin in the brain modulate spatial learning and memory.2009

    • Author(s)
      Y.Oomura, S.Aou, K.Fukunaga, S.Moriguchi, K.Sasaki
    • Journal Title

      Ross.Fiziol.Zh.Im.I.M.Sechenova 95

      Pages: 1373-1385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Mitochondrial serine protease HtrA2/Omi as a potential therapeutic target.2009

    • Author(s)
      MS.Bhuiyan, K.Fukunaga
    • Journal Title

      Curr.Drug Targets 10

      Pages: 372-383

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] lomoucine inhibits cathepsin L nuclear translocation, activates autophagy and attenuates toxicity of 6-hydroxydopamine.2009

    • Author(s)
      XF.Fei, ZH.Qin, B.Xiang, LY.Li, F.Han, K.Fukunaga, ZQ.Liang
    • Journal Title

      Brain Res. 1264

      Pages: 85-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Pathophysiological Relevance of Forkhead Transcription Factors in Brain Ischemia2009

    • Author(s)
      K.Fukunaga, N.Shioda
    • Journal Title

      Forkhead Transcription Factor : Vital Elements in Biology and Medicine(ed. K. Maiese)(Landes Bioscience)

      Pages: 130-142

    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation.2009

    • Author(s)
      S.Moriguchi, N.Shioda, F.Han, JZ.Yeh, T.Narahashi, K.Fukunaga
    • Journal Title

      Hippocampus 19

      Pages: 844-854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Role of Akt and ERK signaling in the neurogenesis following brain ischemia2009

    • Author(s)
      N. Shioda, F. Han, K. Fukunaga
    • Journal Title

      Int.Rev.Neurobiol. 85

      Pages: 375-387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Nefiracetain and Galantamine Modulation of Excitatory and Inhibitory Synaptic Transmission via Stimulation of Neuronal Nicotinic Acetylcholine Recentors in Rat Cortical Neurons2009

    • Author(s)
      Moriguchi S, Zhao X, Marszalec W, Yeh JZ, Fukunaga K, Narahashi T.
    • Journal Title

      Neuroscience. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] The Function of CaM Kinase II in Synaptic Plasticity and Spine Formation2009

    • Author(s)
      K.Fukunaga, N.Shioda, E.Miyamoto
    • Journal Title

      Handobook of Neurochemistry and Molecular Neurobiology. Neural Signaling Mechanisms(ed. A. Lajtha. Vol.ed. K. Mikoshiba)(Springer)

      Pages: 163-184

    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Ca2+/Calmodulin-dependent Protein Kinase IV-mediated LIM-kinase Activation Is Critical for Calcium Signal-induced Neurite Outgrowth.2009

    • Author(s)
      M.Takemura, T.Mishima, Y.Wang, J.Kasahara, K.Fukunaga, K.Ohashi, K Mizuno
    • Journal Title

      J.Biol.Chem. 284

      Pages: 28554-28562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by superoxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxyindazole (DY-9836), a novel calmodulin antagonist.2009

    • Author(s)
      M.Lu, F.Han, N.Shioda, S.Moriguchi., Y.Shirasaki, ZH.Qin, K.Fukunaga
    • Journal Title

      Mol.Pharmacol. 75

      Pages: 101-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Improvement of depressive behaviors by nefiracetam is associated with activation of CaM kinases in olfactory bulbectomized mice2009

    • Author(s)
      F. Han, T. Nakano, Y. Yamamoto, N. Shioda, YM. Lu, K. Fukunaga
    • Journal Title

      Brain Res. 1265

      Pages: 205-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Phenylephrine-induced cardiomyocyte injury is triggered by super oxide generation through uncoupled endothelial nitric-oxide synthase and ameliorated by 342[4-(3-chloro-2-methylphenyl)-1-pipera zinyllethy1]-5, 6-dintethoxyindazole (DY-9836), a novel calmodulin antagonist2009

    • Author(s)
      Lu YM, Han F, Shioda N, Moriguchi S, Shirasaki Y, Qin ZH, Fukunaga K.
    • Journal Title

      Mol Pharmacol 75

      Pages: 101-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Pathophysiological Relevance of Forkhead Transcription Factors in Brain Ischemia.2009

    • Author(s)
      K.Fukunaga, N.Shioda
    • Journal Title

      Forkhead Transcription Factor : Vital Elements in Biology and Medicine(ed.K.Maiese)(Landes Bioscience)

      Pages: 130-142

    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Prandial increase of leptin in the brain activates spatial learning and memory.2009

    • Author(s)
      Y.Oomura, S.Aou, K.Fukunaga
    • Journal Title

      Pathophysiology 17

      Pages: 119-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Nefiracetam and galantamine modulation of excitatory and inhibitory synaptic transmission via stimulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons.2009

    • Author(s)
      S.Moriguchi, X.Zhao, W.Marszalec, JZ.Yeh, K.Fukunaga, T.Narahashi
    • Journal Title

      Neuroscience 160

      Pages: 484-491

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Ca2+/Calmodulin-dependent Protein Kinase IV-mediated LIM-kinase Activation Is Critical for Calcium Signal-induced Neurite Outgrowth2009

    • Author(s)
      M.Takemura, T.Mishima, Y.Wang, J.Kasahara, K.Fukunaga, K.Ohashi, K Mizuno
    • Journal Title

      J.Biol.Chem. 284

      Pages: 28554-28562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] IQ-ArfGEF/BRAG1 is a guanine nucleotide exchange factor for Arf6 that interacts with PSD-95 at postsynaptic density of excitatory synapses.2008

    • Author(s)
      H. Sakagami, M. Sanda, M. Fukaya, T. Miyazaki, J. Sukegawa, T. Yanagisawa, T. Suzuki, K. Fukunaga, M. Watanabe, H. Kondo.
    • Journal Title

      Neurosci Res. 60

      Pages: 199-212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways2008

    • Author(s)
      Wen YD, Sheng R, Zhang LS, Han R, Zhang X, Zhang XD, Han F, Fukunaga K, Qin ZH.
    • Journal Title

      Autophagy 4

      Pages: 762-769

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Cytoprotective effect of bis(1-oxy-2-pyridinethiolato)oxovanadiun(IV) on myocardial ischemia/reperfusion injury elicits inhibition of Fas ligand and Bim expression and elevation of FLIP expression2008

    • Author(s)
      MS. Bhuiyan, M. Shibuya, N. Shioda, S. Moriguchi, J. Kasahara, Y. Iwabuchi, K. Fukunaga
    • Journal Title

      Eur.J.Pharmacol. 571

      Pages: 180-188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism2008

    • Author(s)
      F. Han, N. Shioda, S. Moriguchi, ZH. Qin, K. Fukunaga
    • Journal Title

      Neurosci.Lett. 430

      Pages: 275-280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446/ST101) treatment rescues olfactory bulbectomy-induced memory impairment by activating Ca2+/calmodulin kinase II and protein kinase C in mouse hippocampus2008

    • Author(s)
      F. Han, N. Shioda, S. Moriguchi, Y. Yamamoto, AY. Raie, Y. Yamaguchi, M. Hino, K. Fukunaga
    • Journal Title

      J.Pharmacol.Exp.Ther. 326

      Pages: 127-134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Targeting protein kinase B/Akt signaling with vanadium compounds for cardioorotection2008

    • Author(s)
      Bhuiyan MS, Shioda N, Fukunaga, K.
    • Journal Title

      Expert Opin Ther Targets 12

      Pages: 1217-1227

    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders.2008

    • Author(s)
      Yarnasaki N, Maekawa M, Kobayashi K, Kajii Y, Maeda J, Soma M, Takao K, Tanda K, Ohira K, Toyama K, Kanzaki K, Fukunaga K, Sudo Y, Ichinose H, Ikeda M, Iwata N, Ozaki N, Suzuki H, Higuchi M, Suhara T, Yuasa S, Miyakawa T.
    • Journal Title

      Mol Brain. 1

      Pages: 6-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Targeting protein kinase B / Akt signaling with vanadium compounds for cardioprotection2008

    • Author(s)
      Bhuiyan MS, Shioda N, Fukunaga K.
    • Journal Title

      Expert Opin Thar Targets. 12

      Pages: 1217-1227

    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Cardioprotective effect of vanadyl sulfate on ischemia / reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein2008

    • Author(s)
      Bhuiyan MS, Takada Y, Shioda N, Moriguchi S, Kasahara J. Fukunaga K.
    • Journal Title

      Cardidvasc Ther. 26

      Pages: 10-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Nobiletin, a citrus flavonoid with neurotrophic action, augments prote in kinase A-mediated phosphorylation of the AMPA receptor subunit, Glu R1, and the postsynaptic receptor response to glutamate in murine hippocampus.2008

    • Author(s)
      K. Matsuzaki, K. Miyazaki, S. Sakai, H. Yawo, N. Nakata, S. Moriguchi, K. Fukunaga, A. Yokosuka, Y. Sashida, Y. Mimaki, T. Yamakuni, Y. Ohizumi.
    • Journal Title

      Eur J Pharmacol. 578

      Pages: 194-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Cardioprotective effect of vanadyl sulfate on ischemia/reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein2008

    • Author(s)
      MS. Bhuiyan, Y. Takada, N. Shioda, S. Moriguchi, J. Kasahara, K. Fukunaga
    • Journal Title

      Cardiovasc.Ther. 26

      Pages: 10-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Accumulation of beta-amyloid in the brain microvessels accompanies increased hyperphosphorylated tau proteins following microsphere embolism in aged rats2008

    • Author(s)
      F. Han, A. Ali Raie, N. Shioda, ZH. Qin, K. Fukunaga
    • Journal Title

      Neuroscience 153

      Pages: 414-427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Vanadium compounds enhance adult neurogenesis after brain ischemia.2008

    • Author(s)
      N. Shioda, M. Morioka, K. Fukunaga.
    • Journal Title

      Yakugaku Zasshi. 128

      Pages: 413-417

    • NAID

      110006646595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] ZSET1446(ST101)treatment rescues olfactory bulbectomy-induced memory impairment by activating CaM kinase II and protein kinase C in mouse hippocampus.2008

    • Author(s)
      F. Han, N, Shioda, S. Moriguchi, Y .Yamamoto, A.A. Raie, Y. Yamaguchi, M. Hino, K. Fukunaga.
    • Journal Title

      J Pharmacol Exp Ther. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocampal CA1 region2008

    • Author(s)
      Moriguchi S, Shioda N, Han F, Narahashi T, Fukunaga K.
    • Journal Title

      J Neurochem 106

      Pages: 1092-1103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Accumulation of beta-amyloid in the brain microvessels accompanies increased hyperphosphorylated tau proteins following microsphere embolism in aged rats.2008

    • Author(s)
      F. Han, A. A. Raie, N.Shioda, Z. H. Qin, K. Fukunaga
    • Journal Title

      Neuroscience (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Bis(1-oxy-2-pyridinethiolato)oxovanadium(IV) enhances neurogenesis via phosphatidylinositol 3-kinase/Akt and extracellular signal regulated kinase activation in the hippocampal subgranular zone after mouse focal cerebral ischemia2008

    • Author(s)
      N. Shioda, F. Han, M. Morioka, K. Fukunaga
    • Journal Title

      Neuroscience 155

      Pages: 876-887

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] The vanadium (IV) compound rescues septo-hippocampal cholinergic neurons from neurodegeneration in olfactory bulbectomized mice2008

    • Author(s)
      F. Han, N. Shioda, S. Moriguchi, ZH. Qin, K. Fukunaga
    • Journal Title

      Neuroscience 151

      Pages: 671-679

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Ngvel therapeutic strategy for neurogenesis in the neurodegenerative disorders2008

    • Author(s)
      Fukunaga K, Shioda N, Morioka M. Han F.
    • Journal Title

      Nippon Yakurigaku Zasshi. 131

      Pages: 341-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Activation of HtrA2, a mitochondrial serine protease mediates a poptosis : current knowledge on HtrA2 mediated myocardial ischemia/reperfusion injury2008

    • Author(s)
      Bhuiyan MS, Fukunaga K.
    • Journal Title

      Cardiovasc Ther 26

      Pages: 224-232

    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism.2008

    • Author(s)
      F. Han, N. Shioda, S. Moriguchi, Z. H. Qin, K. Fukunaga.
    • Journal Title

      Neurosci Lett. 430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] DY-9760e Inhibits Endothelin-1-induced Cardiomyocyte Hypertrophy Through Inhibition of CaMKII and ERK Activities2008

    • Author(s)
      Lu YM, Shioda N, Han F, Kamata A, Shirasaki Y, Qin ZH, Fukunaga K.
    • Journal Title

      Cardiovasc Ther. 27

      Pages: 17-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocameal CAI region2008

    • Author(s)
      Moriguchi S, Shioda N, Han F, Narahashi T, Fukunaga K.
    • Journal Title

      J Neurochem. 106

      Pages: 1092-1103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders2008

    • Author(s)
      Yamasaki N, Maekawa M, Kobayashi K, Kajii Y, Maeda J., Soma M, Takao K, Tanda K, Ohira K, Toyama K, Kanzaki K, Fukunaga K, Sudo Y, Ichinose H, Ikeda M, Iwata N, Ozaki N, Suzuki H, Higuchi M, Suhara T, Yuasa S, Mivakawa T.
    • Journal Title

      Mol Brain 1

      Pages: 6-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways.2008

    • Author(s)
      Wen YD, Sheng R, Zhang LS, Han R, Zhang X, Zhang XD, Han F, Fukunaga K, Qin ZH.
    • Journal Title

      Autophagy. 4

      Pages: 762-769

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] CLIC4 interacts with histamine H3 receptor and enhances the receptor cell surface expression.2008

    • Author(s)
      K. Maeda, M. Haraguchi, A. Kuramasu, T. Sato, K. Ariake, H. Sakagagai, H. Kondo, K. Yanai, K. Fukunaga, T. Yanagisawa, J. Sukegawa.
    • Journal Title

      Biochem Biophys Res Commun. 369

      Pages: 603-608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Cardioprotective effect of vanadyl sulfate on ischemia/reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein2008

    • Author(s)
      Bhuiyan MS, Takada Y, Shioda N, Moriguchi S, Kasahara J. Fukunaga K.
    • Journal Title

      Cardiovasc Ther 26

      Pages: 10-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Activation of HtrA2, a mitochondrial serine protease mediates a poptosis : current knowledge on HtrA2 mediated myocardial ischemia / reperfusion injury2008

    • Author(s)
      Bhuiyan MS, Fukunaga K.
    • Journal Title

      Cardiovasc Ther. 26

      Pages: 224-232

    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Novel therapeutic strategy for neurogenesis in the neurodegenerative disorders2008

    • Author(s)
      Fukunaga K, Shioda N, Morioka M. Han F
    • Journal Title

      Nippon Yakurigaku Zasshi 131

      Pages: 341-346

    • NAID

      10024382659

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Fatty acid-binding protein regulates LPS-induced TNF-alpha production in mast cells2008

    • Author(s)
      Yamamoto N, Kaneko I, Motohashi K, Sakagami H, Machi Y, Tokuda N, Sawada T, Furukawa H, Ueyama Y, Fukunaga K, Ono M, Kondo H, Owada Y.
    • Journal Title

      Prostaglandins Leukot Essent Fatty Acids 79

      Pages: 21-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659008
  • [Journal Article] Fatty acid-binding protein regulates LPS-induced TNF-alpha production in mast cells2008

    • Author(s)
      Yamamoto N, Kaneko I, Motohashi K, Sakagami H, Adachi Y, Tokuda N, Sawada T, Furukawa H, Ueyama Y, Fukunaga K, Ono M, Kondo H, Owada Y.
    • Journal Title

      Prostaglandins Leukot Essent Fatty Acids. 79

      Pages: 21-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Nefiracetam potentiates NMDA receptor function via PKC activation and reduces magnesium block of NMDA receptor.2007

    • Author(s)
      Shigeki Moriguchi, Norifumi Shioda, Hiroshi Maejima, Xilong Zhao, William Marszalec, Jay Z. Yeh, Kohji Fukunaga and Toshio Narahashi
    • Journal Title

      Molecular Pharmacology 71

      Pages: 580-587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18059003
  • [Journal Article] Brain embolism-induced injury of vascular endothelial cells and a novel vasoprotective drug2007

    • Author(s)
      F. Han and K. Fukunaga
    • Journal Title

      Yakugaku Zasshi. 127

      Pages: 743-748

    • NAID

      110006242881

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Neuroprotective effects of prostaglandin A(1)in rat models of permanent focal cerebral ischemia are associated with unclear factor-kappaB inhibition and peroxisome proliferatonuclear factor-factor-kappaB inhibition and peroxisome proliferator-activated receptor-gamma up-regulation.2007

    • Author(s)
      H. L. Zhang., ZL Gu, SI Savitz, F. Han, K. Fukunaga, Z. H. Qin
    • Journal Title

      J Neurosci Res. 86

      Pages: 1132-1141

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Imbalance between CaM kinase II and calcineurin activities imparis caffeine-induced calcium relase in hypertrophic cardiomyoc2007

    • Author(s)
      Ying-Mei Lu, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Jiro Kasahara, Yasufumi Shirasaki, Zheng-Hong Qin and Kohji Fukunaga
    • Journal Title

      Biochemical Pharmacology 74

      Pages: 1727-1737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18059003
  • [Journal Article] Ovariectomy augments pressure overload-induced hypertrophy associated with changes in Akt and nitric oxide synthase signaling pathways in female rats.2007

    • Author(s)
      M. S. Bhuiyan, N. Shioda and K. Fukunaga.
    • Journal Title

      Am J Physiol Endocrinol Metab. 293

      Pages: 1606-1614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia2007

    • Author(s)
      N. Shioda, T. Ishigami, F. Han, S. Moriguchi, M. Shibuya, Y. Iwabuchi, K. Fukunaga
    • Journal Title

      Neuroscience 148

      Pages: 221-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia.2007

    • Author(s)
      N. Shioda, F. Han, S. Moriguchi and K. Fukunaga
    • Journal Title

      Journal of Neurochemistry 102

      Pages: 1506-1517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390150
  • [Journal Article] Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes.2007

    • Author(s)
      Y-M. Lu, N. Shioda, F. Han, S. Moriguchi, J. Kasahara, Y. Shirasaki, Z. H. Qin, K. Fukunaga.
    • Journal Title

      Biochem Pharmacol. 74

      Pages: 1727-1737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-193